EuRBPDB

Mus_caroliFamily: THRAP3_BCLAF1 Number of Genes: 3
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Bclaf1
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Bclaf3

Introduction

Pfam

This family includes thyroid hormone receptor-associated protein 3 (THRAP3), which is a spliceosome component and a subunit of the TRAP complex which plays a role in pre-mRNA splicing and in mRNA decay [1]. It also includes the transcriptional repressor Bcl-2-associated transcription factor 1 (BCLAF1) [2].

InterPro

This family includes thyroid hormone receptor-associated protein 3 (THRAP3), which is a spliceosome component and a subunit of the TRAP complex which plays a role in pre-mRNA splicing and mRNA decay [PUBMED:20123736]. It also includes the transcriptional repressor Bcl-2-associated transcription factor 1 (BCLAF1) [PUBMED:10330179].

Reference

  1. Lee KM, Hsu IaW, Tarn WY;, Nucleic Acids Res. 2010;38:3340-3350.: TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation. PUBMED:20123736 EPMC:20123736 .

  2. Kasof GM, Goyal L, White E;, Mol Cell Biol. 1999;19:4390-4404.: Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. PUBMED:10330179 EPMC:10330179.