EuRBPDB

Mus_musculus_c3hhejFamily: THRAP3_BCLAF1 Number of Genes: 3

Ensembl ID	Symbol	Entrez ID
MGP_C3HHeJ_G0016815	Bclaf1	-
MGP_C3HHeJ_G0028470	Thrap3	-
MGP_C3HHeJ_G0035895	A830080D01Rik	-

Introduction

Pfam

This family includes thyroid hormone receptor-associated protein 3 (THRAP3), which is a spliceosome component and a subunit of the TRAP complex which plays a role in pre-mRNA splicing and in mRNA decay [1]. It also includes the transcriptional repressor Bcl-2-associated transcription factor 1 (BCLAF1) [2].

InterPro

This family includes thyroid hormone receptor-associated protein 3 (THRAP3), which is a spliceosome component and a subunit of the TRAP complex which plays a role in pre-mRNA splicing and mRNA decay [PUBMED:20123736]. It also includes the transcriptional repressor Bcl-2-associated transcription factor 1 (BCLAF1) [PUBMED:10330179].

Reference

Lee KM, Hsu IaW, Tarn WY;, Nucleic Acids Res. 2010;38:3340-3350.: TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation. PUBMED:20123736 EPMC:20123736 .
Kasof GM, Goyal L, White E;, Mol Cell Biol. 1999;19:4390-4404.: Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. PUBMED:10330179 EPMC:10330179.