Ensembl ID | Symbol | Entrez ID | RBD | RBPome | PRI | Expresion | Pathway | Phenotype | Paralog | Ortholog | GO |
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The XS (rice gene X and SGS3) domain is found in a family of plant proteins including gene X Q9SBW2 and SGS3 Q9LDX1. SGS3 is thought to be involved in post-transcriptional gene silencing (PTGS). This domain contains a conserved aspartate residue that may be functionally important. The XS domain has recently been predicted to possess an RRM-like RNA-binding domain [1] by fold recognition.
This XS (named after rice gene X and SGS3) domain is a single-stranded RNA-binding domain (RBD) and possesses a unique version of a RNA recognition motif (RRM) fold [PUBMED:18635957]. It is conserved in a family of plant proteins including gene X and SGS3. Although its function is still unknown, the plant SGS3 proteins are thought to be involved in post-transcriptional gene silencing (PTGS) pathways [PUBMED:22592791]. In addition, they contain a conserved aspartate residue that may be functionally important.
Zhang D, Trudeau VL; , Cell Cycle. 2008;7:2268-2270.: The XS domain of a plant specific SGS3 protein adopts a unique RNA recognition motif (RRM) fold. PUBMED:18635957 EPMC:18635957.