EuRBPDB

Mus_musculus_pwkphjFamily: tRNA_m1G_MT Number of Genes: 3
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Trmt10c
-
Trmt10a
-
Trmt10b
-

Introduction

Pfam

This is a family of tRNA (Guanine-1)-methyltransferases EC:2.1.1.31. In E.coli K12 this enzyme catalyses the conversion of a guanosine residue to N1-methylguanine in position 37, next to the anticodon, in tRNA [1].

InterPro

This domain is found in tRNA methyltransferases including tRNA (guanine-N(1)-)-methyltransferases (TRMD) and mitochondrial ribonuclease P protein 1. Proteins containing this domain also include tRNA (guanine(9)-N1)-methyltransferase (Trm10) from yeasts.

Reference

  1. Hjalmarsson KJ, Bystrom AS, Bjork GR; , J Biol Chem 1983;258:1343-1351.: Purification and characterization of transfer RNA (guanine- 1)methyltransferase from Escherichia coli. PUBMED:6337136 EPMC:6337136.