EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24306026	Ehd3, a regulator of vesicular trafficking, is silenced in gliomas and functions as a tumor suppressor by controlling cell cycle arrest and apoptosis.	Carcinogenesis	2014 Apr	Chukkapalli S	doi: 10.1093/carcin/bgt399
27811356	Spatio-temporal regulation of EGFR signaling by the Eps15 homology domain-containing protein 3 (EHD3).	Oncotarget	2016 Nov 29	Amessou M	doi: 10.18632/oncotarget.13008.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr2	31266476	Silent	novel	G460G	0.42
BLCA	chr2	31234696	Silent	novel	L25L	0.16
BLCA	chr2	31234538	5'UTR	novel		0.6
BLCA	chr2	31234791	Missense_Mutation	novel	N57S	0.33
BLCA	chr2	31266657	Silent	novel	L521L	0.11
BLCA	chr2	31260684	Missense_Mutation	rs201814896	T226M	0.49
BLCA	chr2	31261699	Silent	novel	L356L	0.11
BRCA	chr2	31266675	Frame_Shift_Del	novel	*P528Rfs20**	0.5
BRCA	chr2	31261652	Frame_Shift_Del	novel	*R341Gfs13**	0.13
BRCA	chr2	31234699	Missense_Mutation	NA	K26N	0.27
BRCA	chr2	31260739	Silent	NA	V244V	0.52
BRCA	chr2	31266567	Missense_Mutation	NA	D491N	0.54
BRCA	chr2	31266724	3'UTR	novel		0.6
CESC	chr2	31266744	3'UTR	rs749601475		0.56
CESC	chr2	31260810	Frame_Shift_Del	novel	*K269Nfs40**	0.06
CESC	chr2	31268192	3'UTR	novel		0.33
CESC	chr2	31260817	Silent	novel	L270L	0.3
CESC	chr2	31266359	Silent	novel	P421P	0.11
CESC	chr2	31266697	Missense_Mutation	novel	A534D	0.31
CESC	chr2	31267616	3'UTR	novel		0.34
CESC	chr2	31260671	Missense_Mutation	NA	D222N	0.5
CESC	chr2	31244382	Silent	rs146965464	N112N	0.15
CESC	chr2	31234664	Missense_Mutation	novel	P15A	0.34
CESC	chr2	31266390	Missense_Mutation	NA	E432K	0.19
COAD	chr2	31260810	Missense_Mutation	rs775181095	R268Q	0.25
COAD	chr2	31266200	Silent	NA	F368F	0.36
COAD	chr2	31260770	Missense_Mutation	rs138007410	G255S	0.34
COAD	chr2	31266399	Missense_Mutation	rs765964312	D435N	0.36
COAD	chr2	31261654	Missense_Mutation	rs370790409	R341W	0.37
COAD	chr2	31261671	Silent	NA	H346H	0.09
COAD	chr2	31260784	Silent	NA	S259S	0.33
COAD	chr2	31266631	Missense_Mutation	novel	L512P	0.33
COAD	chr2	31234751	Missense_Mutation	novel	E44K	0.41
COAD	chr2	31244424	Silent	rs761082442	N126N	0.3
COAD	chr2	31266306	Missense_Mutation	rs183394828	R404W	0.38
COAD	chr2	31234751	Missense_Mutation	novel	E44K	0.36
COAD	chr2	31244383	Missense_Mutation	rs780938047	A113T	0.55	MMR_HSR1
COAD	chr2	31244344	Missense_Mutation	novel	V100M	0.07	MMR_HSR1
COAD	chr2	31260769	Silent	NA	I254I	0.44
COAD	chr2	31260595	Silent	NA	I196I	0.1
COAD	chr2	31234780	Silent	NA	A53A	0.3
COAD	chr2	31260568	Silent	novel	L187L	0.17
COAD	chr2	31260607	Missense_Mutation	NA	F200L	0.35	MMR_HSR1
COAD	chr2	31266338	Silent	rs771037253	F414F	0.42
COAD	chr2	31260862	Silent	NA	L285L	0.12
COAD	chr2	31261642	Missense_Mutation	rs138474287	E337K	0.22
COAD	chr2	31260614	Frame_Shift_Del	novel	*V203Sfs16**	0.28	MMR_HSR1
ESCA	chr2	31260557	Missense_Mutation	rs778088572	R184C	0.25	MMR_HSR1
ESCA	chr2	31244355	Silent	novel	G103G	0.29
ESCA	chr2	31261703	Missense_Mutation	NA	K357R	0.11
ESCA	chr2	31266623	Silent	novel	K509K	0.26
ESCA	chr2	31234760	Missense_Mutation	novel	S47P	0.25
GBM	chr2	31260890	Missense_Mutation	NA	N295D	0.25
GBM	chr2	31244446	Missense_Mutation	NA	N134Y	0.35	MMR_HSR1
GBM	chr2	31244412	Missense_Mutation	novel	F122L	0.07	MMR_HSR1
GBM	chr2	31260867	Missense_Mutation	rs763181531	R287Q	0.47
GBM	chr2	31260736	Silent	rs758911736	I243I	0.06
GBM	chr2	31234721	Missense_Mutation	novel	L34M	0.36
GBM	chr2	31266289	Missense_Mutation	rs370044897	R398H	0.37
GBM	chr2	31261609	Missense_Mutation	NA	N326Y	0.07
GBM	chr2	31261689	Missense_Mutation	NA	D352E	0.1
HNSC	chr2	31266334	Missense_Mutation	rs778192677	A413V	0.24
HNSC	chr2	31260661	Silent	novel	L218L	0.25
HNSC	chr2	31260611	Nonsense_Mutation	novel	E202*	0.32	MMR_HSR1
HNSC	chr2	31261677	Silent	rs772559220	I348I	0.14
HNSC	chr2	31266527	Silent	novel	P477P	0.34
KICH	chr2	31261654	Missense_Mutation	rs370790409	R341W	0.69
KIRC	chr2	31261572	Silent	novel	S313S	0.4
KIRC	chr2	31261623	Silent	NA	E330E	0.33
LGG	chr2	31244427	Silent	novel	A127A	0.13
LGG	chr2	31266587	Silent	rs541802949	D497D	0.4
LIHC	chr2	31234588	5'UTR	novel		0.4
LIHC	chr2	31249449	Silent	novel	E161E	0.55
LIHC	chr2	31234555	5'UTR	novel		0.61
LIHC	chr2	31266489	Missense_Mutation	novel	A465T	0.26
LUAD	chr2	31261600	Frame_Shift_Del	novel	*K324Rfs33**	0.24
LUAD	chr2	31266389	Silent	NA	G431G	0.4
LUAD	chr2	31260684	Missense_Mutation	novel	T226K	0.15
LUAD	chr2	31260699	Missense_Mutation	novel	R231L	0.18
LUAD	chr2	31234533	5'UTR	novel		0.14
LUAD	chr2	31261665	Silent	novel	R344R	0.05
LUAD	chr2	31266679	Missense_Mutation	novel	P528Q	0.2
LUAD	chr2	31244362	Nonsense_Mutation	novel	E106*	0.08	MMR_HSR1
LUAD	chr2	31244425	Missense_Mutation	rs372292180	A127T	0.25	MMR_HSR1
LUAD	chr2	31266544	Missense_Mutation	NA	K483M	0.32
LUAD	chr2	31266440	Silent	rs779019701	Y448Y	0.11
LUAD	chr2	31260780	Missense_Mutation	NA	W258L	0.39
LUAD	chr2	31249467	Splice_Region	NA	R167R	0.41
LUAD	chr2	31261680	Silent	NA	S349S	0.22
LUAD	chr2	31260792	Missense_Mutation	novel	L262H	0.19
LUAD	chr2	31266504	Nonsense_Mutation	NA	E470*	0.33
LUAD	chr2	31244427	Frame_Shift_Ins	novel	*G129Wfs15**	0.4	MMR_HSR1
LUAD	chr2	31260675	Missense_Mutation	novel	Q223R	0.17
LUAD	chr2	31266268	Frame_Shift_Del	novel	*Q392Sfs5**	0.17
LUAD	chr2	31266306	Missense_Mutation	rs183394828	R404W	0.2
LUSC	chr2	31260549	Missense_Mutation	novel	R181L	0.56	MMR_HSR1
LUSC	chr2	31234681	Silent	rs374598778	T20T	0.33
LUSC	chr2	31260783	Missense_Mutation	NA	S259Y	0.17
LUSC	chr2	31249434	Silent	rs138864640	G156G	0.2
LUSC	chr2	31260856	Silent	novel	Q283Q	0.3
LUSC	chr2	31244328	Silent	novel	T94T	0.27
LUSC	chr2	31266408	Missense_Mutation	novel	E438K	0.38
LUSC	chr2	31260809	Missense_Mutation	rs771567803	R268W	0.28
LUSC	chr2	31244395	Missense_Mutation	rs769119216	D117N	0.62	MMR_HSR1
LUSC	chr2	31244319	Silent	novel	E91E	0.11
LUSC	chr2	31244288	Missense_Mutation	novel	Q81L	0.35	MMR_HSR1
LUSC	chr2	31244320	Missense_Mutation	novel	P92S	0.13	MMR_HSR1
OV	chr2	31260709	Silent	novel	G234G	0.13
OV	chr2	31234803	Missense_Mutation	novel	V61A	0.14	MMR_HSR1
OV	chr2	31266489	Missense_Mutation	NA	A465P	0.18
OV	chr2	31260825	Missense_Mutation	novel	A273D	0.06
OV	chr2	31260634	Missense_Mutation	NA	N209K	0.28	MMR_HSR1
OV	chr2	31261645	Missense_Mutation	NA	I338V	0.19
OV	chr2	31266697	Missense_Mutation	novel	A534V	0.11
OV	chr2	31266703	Nonstop_Mutation	novel	536Lext40	0.19
PAAD	chr2	31234743	Missense_Mutation	rs763234044	R41H	0.26
PAAD	chr2	31244437	Missense_Mutation	rs765230348	A131T	0.28	MMR_HSR1
PAAD	chr2	31260629	Missense_Mutation	novel	K208Q	0.27	MMR_HSR1
PAAD	chr2	31260822	Missense_Mutation	novel	E272A	0.07
PAAD	chr2	31261639	Missense_Mutation	novel	A336T	0.24
PAAD	chr2	31266385	Missense_Mutation	novel	A430V	0.09
PRAD	chr2	31249466	Frame_Shift_Del	novel		0.07
PRAD	chr2	31261668	Silent	novel	E345E	0.41
READ	chr2	31260881	Missense_Mutation	NA	R292C	0.44
READ	chr2	31234662	Frame_Shift_Ins	novel	*E16Rfs8**	0.23
READ	chr2	31266594	Missense_Mutation	NA	E500K	0.48
READ	chr2	31260847	Silent	novel	R280R	0.28
READ	chr2	31260893	Missense_Mutation	NA	D296N	0.46
SARC	chr2	31261599	Missense_Mutation	novel	F322L	0.19
SKCM	chr2	31266377	Silent	novel	G427G	0.37
SKCM	chr2	31234830	Missense_Mutation	NA	G70E	0.59	MMR_HSR1
SKCM	chr2	31260586	Missense_Mutation	NA	K193N	0.21	MMR_HSR1
SKCM	chr2	31260736	Silent	rs758911736	I243I	0.27
SKCM	chr2	31234646	Missense_Mutation	NA	D9N	0.29
SKCM	chr2	31260818	Missense_Mutation	NA	F271I	0.21
SKCM	chr2	31266706	3'UTR	novel		0.21
SKCM	chr2	31261659	Silent	novel	I342I	0.31
SKCM	chr2	31266689	Silent	rs267599346	R531R	0.5
SKCM	chr2	31266690	Missense_Mutation	novel	K532Q	0.5
SKCM	chr2	31260679	Silent	rs757561609	I224I	0.32
SKCM	chr2	31260841	Silent	novel	L278L	0.53
SKCM	chr2	31260908	Missense_Mutation	NA	A301T	0.61
SKCM	chr2	31261671	Silent	NA	H346H	0.28
SKCM	chr2	31260680	Missense_Mutation	rs765669139	E225K	0.28
SKCM	chr2	31260783	Missense_Mutation	NA	S259F	0.42
SKCM	chr2	31249402	Silent	NA	L146L	0.26
SKCM	chr2	31260799	Silent	NA	I264I	0.43
SKCM	chr2	31266658	Missense_Mutation	NA	L521R	0.28
SKCM	chr2	31260736	Silent	rs758911736	I243I	0.28
SKCM	chr2	31266399	Missense_Mutation	rs765964312	D435N	0.66
SKCM	chr2	31260736	Silent	rs758911736	I243I	0.47
SKCM	chr2	31244408	Missense_Mutation	NA	P121L	0.16	MMR_HSR1
SKCM	chr2	31266257	Silent	NA	A387A	0.11
SKCM	chr2	31260829	Silent	novel	E274E	0.25
SKCM	chr2	31261582	Missense_Mutation	novel	E317K	0.31
SKCM	chr2	31266715	3'UTR	novel		0.42
SKCM	chr2	31234682	Missense_Mutation	NA	V21M	0.38
SKCM	chr2	31249440	Silent	novel	L158L	0.36
SKCM	chr2	31234590	5'UTR	novel		0.28
SKCM	chr2	31234591	5'UTR	novel		0.28
SKCM	chr2	31260724	Silent	NA	S239S	0.22
SKCM	chr2	31266665	Silent	novel	A523A	0.34
SKCM	chr2	31266666	Missense_Mutation	novel	H524Y	0.32
SKCM	chr2	31244367	Silent	novel	G107G	0.45
SKCM	chr2	31266213	Missense_Mutation	novel	P373S	0.2
STAD	chr2	31260706	Silent	rs147844646	Y233Y	0.59
STAD	chr2	31260726	Frame_Shift_Ins	novel	*K242Efs25**	0.22
STAD	chr2	31266233	Silent	NA	L379L	0.16
STAD	chr2	31266375	Missense_Mutation	novel	G427W	0.11
STAD	chr2	31266711	3'UTR	novel		0.17
STAD	chr2	31266685	Missense_Mutation	novel	K530T	0.11
STAD	chr2	31266295	Missense_Mutation	NA	E400G	0.09
STAD	chr2	31260695	Missense_Mutation	NA	M230L	0.16
STAD	chr2	31260706	Silent	rs147844646	Y233Y	0.37
STAD	chr2	31234687	Silent	NA	S22S	0.08
STAD	chr2	31244383	Missense_Mutation	rs780938047	A113T	0.33	MMR_HSR1
STAD	chr2	31260534	Missense_Mutation	NA	E176G	0.09	MMR_HSR1
THYM	chr2	31266711	3'UTR	novel		0.29
UCEC	chr2	31266245	Silent	rs777858365	D383D	0.23
UCEC	chr2	31234721	Silent	NA	L34L	0.32
UCEC	chr2	31266335	Silent	rs535804497	A413A	0.24
UCEC	chr2	31261554	Silent	rs201209745	H307H	0.23
UCEC	chr2	31266399	Missense_Mutation	rs765964312	D435N	0.25
UCEC	chr2	31249374	Silent	novel	F136F	0.41
UCEC	chr2	31266560	Silent	rs770412826	A488A	0.33
UCEC	chr2	31234801	Missense_Mutation	novel	M60I	0.42
UCEC	chr2	31267612	3'UTR	novel		0.27
UCEC	chr2	31268314	3'UTR	novel		0.16
UCEC	chr2	31268319	3'UTR	novel		0.44
UCEC	chr2	31261711	Nonsense_Mutation	novel	Q360*	0.3
UCEC	chr2	31260710	Missense_Mutation	NA	A235T	0.15
UCEC	chr2	31267639	3'UTR	novel		0.48
UCEC	chr2	31244301	Silent	NA	G85G	0.29
UCEC	chr2	31260650	Nonsense_Mutation	rs751219079	R215*	0.43	MMR_HSR1
UCEC	chr2	31266214	Missense_Mutation	rs200750745	P373L	0.22
UCEC	chr2	31249374	Silent	novel	F136F	0.23
UCEC	chr2	31260607	Missense_Mutation	NA	F200L	0.46	MMR_HSR1
UCEC	chr2	31267429	3'UTR	novel		0.14
UCEC	chr2	31260629	Missense_Mutation	novel	K208E	0.29	MMR_HSR1
UCEC	chr2	31260825	Missense_Mutation	novel	A273V	0.33
UCEC	chr2	31266225	Missense_Mutation	novel	K377E	0.34
UCEC	chr2	31268142	3'UTR	novel		0.07
UCEC	chr2	31244382	Silent	rs146965464	N112N	0.55
UCEC	chr2	31266888	3'UTR	novel		0.28
UCEC	chr2	31260736	Silent	rs758911736	I243I	0.26
UCEC	chr2	31266593	Silent	rs201490817	D499D	0.4
UCEC	chr2	31266442	Missense_Mutation	novel	D449A	0.32
UCEC	chr2	31266664	Missense_Mutation	novel	A523D	0.51
UCEC	chr2	31268353	3'UTR	novel		0.53
UCEC	chr2	31266228	Missense_Mutation	NA	L378M	0.35
UCEC	chr2	31266449	Silent	NA	I451I	0.39
UCEC	chr2	31249374	Silent	novel	F136F	0.34
UCEC	chr2	31266338	Silent	rs771037253	F414F	0.33
UCEC	chr2	31267626	3'UTR	novel		0.44
UCEC	chr2	31267995	3'UTR	novel		0.21
UCEC	chr2	31261641	Silent	rs367940907	A336A	0.17
UCEC	chr2	31267470	3'UTR	novel		0.22
UCEC	chr2	31268282	3'UTR	rs567732274		0.19
UCEC	chr2	31260867	Missense_Mutation	rs763181531	R287Q	0.46
UCEC	chr2	31267739	3'UTR	novel		0.36
UCEC	chr2	31234774	Missense_Mutation	novel	E51D	0.41
UCEC	chr2	31260881	Missense_Mutation	NA	R292C	0.37
UCEC	chr2	31267975	3'UTR	novel		0.35
UCEC	chr2	31268063	3'UTR	novel		0.32
UCEC	chr2	31234815	Missense_Mutation	NA	G65D	0.42	MMR_HSR1
UCEC	chr2	31260607	Missense_Mutation	NA	F200L	0.53	MMR_HSR1
UCEC	chr2	31249417	Missense_Mutation	rs116417209	V151I	0.31	MMR_HSR1
UCEC	chr2	31244382	Silent	rs146965464	N112N	0.55
UCEC	chr2	31260785	Missense_Mutation	novel	H260Y	0.23
UCEC	chr2	31266848	3'UTR	novel		0.5
UCEC	chr2	31266355	Missense_Mutation	NA	G420D	0.4
UCEC	chr2	31244395	Missense_Mutation	rs769119216	D117N	0.36	MMR_HSR1
UCEC	chr2	31261641	Silent	rs367940907	A336A	0.33
UCEC	chr2	31234786	Silent	NA	F55F	0.4
UCEC	chr2	31266268	Missense_Mutation	novel	A391V	0.24
UCEC	chr2	31249422	Silent	rs61749077	I152I	0.42
UCEC	chr2	31234690	Missense_Mutation	novel	E23D	0.4
UCEC	chr2	31244362	Missense_Mutation	novel	E106K	0.33	MMR_HSR1
UCEC	chr2	31260637	Silent	rs557753544	H210H	0.19
UCEC	chr2	31260791	Missense_Mutation	novel	L262I	0.15
UCEC	chr2	31261568	Missense_Mutation	novel	S312I	0.12
UCEC	chr2	31260574	Silent	rs537831838	F189F	0.43
UCEC	chr2	31266256	Missense_Mutation	novel	A387V	0.37
UCEC	chr2	31268387	3'UTR	novel		0.48
UCEC	chr2	31260759	Missense_Mutation	rs755907641	R251Q	0.16
UCEC	chr2	31249374	Silent	novel	F136F	0.4
UCEC	chr2	31261555	Missense_Mutation	novel	A308T	0.44
UCEC	chr2	31260679	Silent	rs757561609	I224I	0.32
UCEC	chr2	31260882	Missense_Mutation	rs766994253	R292H	0.24
UCEC	chr2	31261655	Missense_Mutation	rs375110725	R341Q	0.42
UCEC	chr2	31268339	3'UTR	novel		0.09
UVM	chr2	31261636	Missense_Mutation	novel	L335V	0.56

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	AMP	0.2271	0.099937
KIRP	DEL	0.0278	0.08832
PAAD	DEL	0.0924	0.2014
TGCT	AMP	0.26	0.0050216
THCA	DEL	0.022	0.1806

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00021	Kaplan-Meier Survival Analysis
STAD	0.00036	Kaplan-Meier Survival Analysis
MESO	0.024	Kaplan-Meier Survival Analysis
LUSC	0.03	Kaplan-Meier Survival Analysis
KIRP	0.028	Kaplan-Meier Survival Analysis
PAAD	0.013	Kaplan-Meier Survival Analysis
BLCA	0.014	Kaplan-Meier Survival Analysis
UCEC	0.045	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
UVM	0.0014	Kaplan-Meier Survival Analysis
OV	0.045	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000013016 (Gene tree)
Gene ID: 30845
Gene Symbol: EHD3
Alias: PAST3
Full Name: EH domain containing 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 35,438 bases
Position: chr2:31,234,014-31,269,451
Accession: 3244
RBP type: canonical RBP
Summary: EHD3 (EH Domain Containing 3) is a Protein Coding gene. Among its related pathways are Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) and Factors involved in megakaryocyte development and platelet production. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and GTP binding. An important paralog of this gene is EHD1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000327116	MMR_HSR1	PF01926.23	2.2e-08	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000322054	EHD3-201	4636	-	ENSP00000327116	535 (aa)	-	Q9NZN3

Gene Model

Click here to download ENSG00000013016's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04144	Endocytosis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000013016	Mean Platelet Volume	1E-12	22139419
ENSG00000013016	Mean Platelet Volume	3E-11	19820697
ENSG00000013016	Estradiol	5E-7	22675492
ENSG00000013016	Mean Platelet Volume	4E-6	24026423
ENSG00000013016	Platelet Count	9E-14	22139419

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000013016	rs649729	2	31241519	A	High light scatter reticulocyte percentage of red cells	27863252	[0.018-0.033] unit decrease	0.02540754	EFO_0007986
ENSG00000013016	rs655029	2	31254972	A	Mean platelet volume	27863252	[0.082-0.097] unit decrease	0.08953487	EFO_0004584
ENSG00000013016	rs649729	2	31241519	T	Mean platelet volume	22139419	[0.006-0.01] ln(fl) increase	0.008	EFO_0004584
ENSG00000013016	rs625132	2	31259434	G	Platelet count	22139419	[3.12-5.35] 10^9/l increase	4.236	EFO_0004309
ENSG00000013016	rs649729	2	31241519	A	Mean platelet volume	24026423	[NR] unit decrease	0.07	EFO_0004584
ENSG00000013016	rs647316	2	31241963	A	Mean platelet volume	19820697	[0.006-0.014] fl increase	0.01	EFO_0004584
ENSG00000013016	rs649729	2	31241519	A	Reticulocyte fraction of red cells	27863252	[0.018-0.033] unit decrease	0.02521163	EFO_0007986
ENSG00000013016	rs146859437	2	31247574	C	Platelet distribution width	27863252	[0.17-0.29] unit decrease	0.2324107	EFO_0007984
ENSG00000013016	rs655029	2	31254972	A	Platelet distribution width	27863252	[0.12-0.14] unit decrease	0.1286083	EFO_0007984
ENSG00000013016	rs649729	2	31241519	A	High light scatter reticulocyte count	27863252	[0.015-0.031] unit decrease	0.02308318	EFO_0007986
ENSG00000013016	rs655029	2	31254972	A	Plateletcrit	27863252	[0.028-0.044] unit increase	0.0360763	EFO_0007985
ENSG00000013016	rs655029	2	31254972	A	Platelet count	27863252	[0.066-0.081] unit increase	0.07349026	EFO_0004309
ENSG00000013016	rs597800	2	31251376	C	Estradiol levels	22675492	[NR] unit decrease	0.148	EFO_0004697
ENSG00000013016	rs4952073	2	31235115	?	White blood cell count	30595370			EFO_0004308
ENSG00000013016	rs184409696	2	31253905	?	White blood cell count	30595370			EFO_0004308
ENSG00000013016	rs4952073	2	31235115	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000013016's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000013016	EHD3	100	97.570	ENSAMEG00000004282	EHD3	100	97.570	Ailuropoda_melanoleuca
ENSG00000013016	EHD3	100	91.776	ENSACIG00000015462	ehd3	100	91.776	Amphilophus_citrinellus
ENSG00000013016	EHD3	100	78.131	ENSAOCG00000001953	-	100	78.879	Amphiprion_ocellaris
ENSG00000013016	EHD3	100	91.776	ENSAPEG00000018380	ehd3	100	91.776	Amphiprion_percula
ENSG00000013016	EHD3	100	91.963	ENSATEG00000002224	ehd3	100	91.963	Anabas_testudineus
ENSG00000013016	EHD3	100	96.636	ENSAPLG00000010467	EHD3	100	96.636	Anas_platyrhynchos
ENSG00000013016	EHD3	100	89.907	ENSACAG00000007103	EHD3	100	89.907	Anolis_carolinensis
ENSG00000013016	EHD3	100	99.252	ENSANAG00000020422	EHD3	100	99.252	Aotus_nancymaae
ENSG00000013016	EHD3	100	91.963	ENSACLG00000007581	ehd3	100	91.963	Astatotilapia_calliptera
ENSG00000013016	EHD3	100	87.161	ENSAMXG00000042972	ehd3	100	87.161	Astyanax_mexicanus
ENSG00000013016	EHD3	100	97.009	ENSBTAG00000001662	EHD3	100	97.009	Bos_taurus
ENSG00000013016	EHD3	100	99.439	ENSCJAG00000003137	EHD3	100	99.439	Callithrix_jacchus
ENSG00000013016	EHD3	100	98.318	ENSCAFG00000005348	EHD3	100	98.318	Canis_familiaris
ENSG00000013016	EHD3	99	95.677	ENSCAFG00020023684	EHD3	98	95.677	Canis_lupus_dingo
ENSG00000013016	EHD3	100	96.636	ENSCHIG00000017794	EHD3	100	96.636	Capra_hircus
ENSG00000013016	EHD3	100	98.318	ENSTSYG00000036583	EHD3	100	98.318	Carlito_syrichta
ENSG00000013016	EHD3	100	98.692	ENSCPOG00000034108	EHD3	100	98.692	Cavia_porcellus
ENSG00000013016	EHD3	100	99.252	ENSCCAG00000029860	EHD3	100	99.252	Cebus_capucinus
ENSG00000013016	EHD3	100	99.626	ENSCATG00000044604	EHD3	100	99.626	Cercocebus_atys
ENSG00000013016	EHD3	100	99.252	ENSCLAG00000010983	EHD3	100	99.252	Chinchilla_lanigera
ENSG00000013016	EHD3	100	99.626	ENSCSAG00000011254	EHD3	100	99.626	Chlorocebus_sabaeus
ENSG00000013016	EHD3	100	96.075	ENSCPBG00000011884	EHD3	100	96.075	Chrysemys_picta_bellii
ENSG00000013016	EHD3	100	99.626	ENSCANG00000024283	EHD3	100	99.626	Colobus_angolensis_palliatus
ENSG00000013016	EHD3	100	97.196	ENSCGRG00001020979	Ehd3	100	97.196	Cricetulus_griseus_chok1gshd
ENSG00000013016	EHD3	100	97.196	ENSCGRG00000013157	Ehd3	100	97.196	Cricetulus_griseus_crigri
ENSG00000013016	EHD3	100	90.841	ENSCSEG00000019195	ehd3	100	90.841	Cynoglossus_semilaevis
ENSG00000013016	EHD3	100	91.963	ENSCVAG00000016197	ehd3	100	91.963	Cyprinodon_variegatus
ENSG00000013016	EHD3	100	92.710	ENSDARG00000007869	ehd3	100	92.710	Danio_rerio
ENSG00000013016	EHD3	100	98.692	ENSDNOG00000039339	EHD3	100	98.692	Dasypus_novemcinctus
ENSG00000013016	EHD3	100	98.692	ENSDORG00000024162	Ehd3	100	98.692	Dipodomys_ordii
ENSG00000013016	EHD3	99	94.151	ENSETEG00000013323	EHD3	98	94.151	Echinops_telfairi
ENSG00000013016	EHD3	100	97.570	ENSEASG00005008635	EHD3	100	97.570	Equus_asinus_asinus
ENSG00000013016	EHD3	100	97.570	ENSECAG00000015195	EHD3	100	97.570	Equus_caballus
ENSG00000013016	EHD3	88	94.191	ENSEEUG00000010447	EHD3	86	94.191	Erinaceus_europaeus
ENSG00000013016	EHD3	99	91.932	ENSELUG00000023984	ehd3	99	91.932	Esox_lucius
ENSG00000013016	EHD3	100	98.505	ENSFCAG00000029627	EHD3	100	98.505	Felis_catus
ENSG00000013016	EHD3	100	96.262	ENSFALG00000011448	EHD3	100	96.262	Ficedula_albicollis
ENSG00000013016	EHD3	100	98.505	ENSFDAG00000017946	EHD3	100	98.505	Fukomys_damarensis
ENSG00000013016	EHD3	100	92.150	ENSFHEG00000018572	ehd3	100	92.150	Fundulus_heteroclitus
ENSG00000013016	EHD3	99	90.262	ENSGMOG00000006447	ehd3	100	90.262	Gadus_morhua
ENSG00000013016	EHD3	100	96.449	ENSGALG00000009086	EHD3	100	96.449	Gallus_gallus
ENSG00000013016	EHD3	100	91.402	ENSGAFG00000005665	ehd3	100	91.402	Gambusia_affinis
ENSG00000013016	EHD3	99	91.573	ENSGACG00000013160	ehd3	96	91.573	Gasterosteus_aculeatus
ENSG00000013016	EHD3	100	96.075	ENSGAGG00000024938	EHD3	100	96.075	Gopherus_agassizii
ENSG00000013016	EHD3	100	99.813	ENSGGOG00000003031	EHD3	100	99.813	Gorilla_gorilla
ENSG00000013016	EHD3	100	91.963	ENSHBUG00000023210	ehd3	100	91.963	Haplochromis_burtoni
ENSG00000013016	EHD3	100	98.692	ENSHGLG00000014803	EHD3	100	98.692	Heterocephalus_glaber_female
ENSG00000013016	EHD3	100	98.692	ENSHGLG00100011636	EHD3	100	98.692	Heterocephalus_glaber_male
ENSG00000013016	EHD3	100	91.589	ENSHCOG00000018418	ehd3	100	91.589	Hippocampus_comes
ENSG00000013016	EHD3	100	91.215	ENSIPUG00000004603	Ehd3	100	91.215	Ictalurus_punctatus
ENSG00000013016	EHD3	100	97.570	ENSSTOG00000028279	EHD3	100	97.570	Ictidomys_tridecemlineatus
ENSG00000013016	EHD3	100	97.757	ENSJJAG00000013415	Ehd3	100	97.757	Jaculus_jaculus
ENSG00000013016	EHD3	100	91.776	ENSKMAG00000018498	ehd3	100	91.776	Kryptolebias_marmoratus
ENSG00000013016	EHD3	100	90.841	ENSLBEG00000009464	ehd3	100	90.841	Labrus_bergylta
ENSG00000013016	EHD3	100	90.654	ENSLOCG00000016786	ehd3	100	90.654	Lepisosteus_oculatus
ENSG00000013016	EHD3	99	96.816	ENSLAFG00000016215	EHD3	97	96.816	Loxodonta_africana
ENSG00000013016	EHD3	100	99.252	ENSMFAG00000033132	EHD3	100	99.252	Macaca_fascicularis
ENSG00000013016	EHD3	100	99.252	ENSMMUG00000003476	EHD3	100	99.252	Macaca_mulatta
ENSG00000013016	EHD3	100	99.252	ENSMNEG00000041202	EHD3	100	99.252	Macaca_nemestrina
ENSG00000013016	EHD3	100	99.626	ENSMLEG00000023912	EHD3	100	99.626	Mandrillus_leucophaeus
ENSG00000013016	EHD3	100	91.776	ENSMAMG00000014744	ehd3	100	91.776	Mastacembelus_armatus
ENSG00000013016	EHD3	100	91.963	ENSMZEG00005012558	ehd3	100	91.963	Maylandia_zebra
ENSG00000013016	EHD3	100	97.757	ENSMAUG00000013239	Ehd3	100	97.757	Mesocricetus_auratus
ENSG00000013016	EHD3	100	96.822	ENSMICG00000043744	EHD3	100	96.822	Microcebus_murinus
ENSG00000013016	EHD3	100	97.757	ENSMOCG00000012572	Ehd3	100	97.757	Microtus_ochrogaster
ENSG00000013016	EHD3	100	77.570	ENSMMOG00000015157	ehd3	100	78.318	Mola_mola
ENSG00000013016	EHD3	100	97.383	ENSMODG00000015505	EHD3	100	97.383	Monodelphis_domestica
ENSG00000013016	EHD3	100	91.589	ENSMALG00000015586	ehd3	100	91.589	Monopterus_albus
ENSG00000013016	EHD3	100	97.383	MGP_CAROLIEiJ_G0021870	Ehd3	100	97.383	Mus_caroli
ENSG00000013016	EHD3	100	97.383	ENSMUSG00000024065	Ehd3	100	97.383	Mus_musculus
ENSG00000013016	EHD3	100	97.570	MGP_PahariEiJ_G0020857	Ehd3	100	97.570	Mus_pahari
ENSG00000013016	EHD3	100	97.196	MGP_SPRETEiJ_G0022782	Ehd3	100	97.196	Mus_spretus
ENSG00000013016	EHD3	89	98.529	ENSMPUG00000005148	EHD3	100	98.529	Mustela_putorius_furo
ENSG00000013016	EHD3	100	95.140	ENSMLUG00000008050	EHD3	100	95.140	Myotis_lucifugus
ENSG00000013016	EHD3	100	98.318	ENSNGAG00000014439	Ehd3	100	98.318	Nannospalax_galili
ENSG00000013016	EHD3	100	91.776	ENSNBRG00000022653	ehd3	100	91.776	Neolamprologus_brichardi
ENSG00000013016	EHD3	89	99.791	ENSNLEG00000015546	EHD3	100	99.791	Nomascus_leucogenys
ENSG00000013016	EHD3	100	96.636	ENSOPRG00000012242	EHD3	98	96.636	Ochotona_princeps
ENSG00000013016	EHD3	100	98.131	ENSODEG00000008117	EHD3	100	98.131	Octodon_degus
ENSG00000013016	EHD3	100	91.963	ENSONIG00000000693	ehd3	100	91.963	Oreochromis_niloticus
ENSG00000013016	EHD3	100	98.694	ENSOCUG00000001228	EHD3	100	98.694	Oryctolagus_cuniculus
ENSG00000013016	EHD3	100	91.402	ENSORLG00000017118	ehd3	100	91.402	Oryzias_latipes
ENSG00000013016	EHD3	100	91.402	ENSORLG00020002121	ehd3	100	91.402	Oryzias_latipes_hni
ENSG00000013016	EHD3	100	91.402	ENSORLG00015020550	ehd3	100	91.402	Oryzias_latipes_hsok
ENSG00000013016	EHD3	100	91.589	ENSOMEG00000000506	ehd3	100	91.589	Oryzias_melastigma
ENSG00000013016	EHD3	100	97.009	ENSOGAG00000000397	EHD3	100	97.009	Otolemur_garnettii
ENSG00000013016	EHD3	100	93.458	ENSOARG00000019698	EHD3	100	94.953	Ovis_aries
ENSG00000013016	EHD3	100	99.813	ENSPPAG00000035288	EHD3	100	99.813	Pan_paniscus
ENSG00000013016	EHD3	100	98.318	ENSPPRG00000002225	EHD3	100	98.318	Panthera_pardus
ENSG00000013016	EHD3	100	98.505	ENSPTIG00000013343	EHD3	100	98.505	Panthera_tigris_altaica
ENSG00000013016	EHD3	100	99.813	ENSPTRG00000011805	EHD3	100	99.813	Pan_troglodytes
ENSG00000013016	EHD3	100	99.626	ENSPANG00000023120	EHD3	100	99.626	Papio_anubis
ENSG00000013016	EHD3	100	91.215	ENSPKIG00000001422	ehd3	100	91.215	Paramormyrops_kingsleyae
ENSG00000013016	EHD3	100	95.888	ENSPSIG00000017757	EHD3	100	95.888	Pelodiscus_sinensis
ENSG00000013016	EHD3	100	91.215	ENSPMGG00000007882	ehd3	100	91.215	Periophthalmus_magnuspinnatus
ENSG00000013016	EHD3	100	97.009	ENSPCIG00000008811	EHD3	100	97.009	Phascolarctos_cinereus
ENSG00000013016	EHD3	100	91.963	ENSPFOG00000010935	ehd3	100	91.963	Poecilia_formosa
ENSG00000013016	EHD3	100	92.150	ENSPLAG00000001005	ehd3	100	92.150	Poecilia_latipinna
ENSG00000013016	EHD3	100	91.963	ENSPMEG00000006514	ehd3	100	91.963	Poecilia_mexicana
ENSG00000013016	EHD3	100	91.776	ENSPREG00000012884	ehd3	100	91.776	Poecilia_reticulata
ENSG00000013016	EHD3	100	99.626	ENSPPYG00000012514	EHD3	100	99.626	Pongo_abelii
ENSG00000013016	EHD3	89	97.280	ENSPCAG00000008166	EHD3	100	97.280	Procavia_capensis
ENSG00000013016	EHD3	100	97.383	ENSPCOG00000013548	EHD3	100	97.383	Propithecus_coquereli
ENSG00000013016	EHD3	98	98.659	ENSPVAG00000002680	EHD3	100	98.659	Pteropus_vampyrus
ENSG00000013016	EHD3	100	91.963	ENSPNYG00000003812	ehd3	100	91.963	Pundamilia_nyererei
ENSG00000013016	EHD3	100	92.336	ENSPNAG00000028984	ehd3	100	92.336	Pygocentrus_nattereri
ENSG00000013016	EHD3	100	97.570	ENSRNOG00000007744	Ehd3	100	97.570	Rattus_norvegicus
ENSG00000013016	EHD3	99	99.623	ENSRBIG00000033877	EHD3	100	93.926	Rhinopithecus_bieti
ENSG00000013016	EHD3	100	99.626	ENSRROG00000045782	EHD3	100	99.626	Rhinopithecus_roxellana
ENSG00000013016	EHD3	100	99.439	ENSSBOG00000030935	EHD3	100	99.439	Saimiri_boliviensis_boliviensis
ENSG00000013016	EHD3	100	96.636	ENSSHAG00000013011	EHD3	100	96.636	Sarcophilus_harrisii
ENSG00000013016	EHD3	100	91.589	ENSSFOG00015014110	ehd3	100	91.589	Scleropages_formosus
ENSG00000013016	EHD3	100	91.402	ENSSMAG00000008537	ehd3	100	91.402	Scophthalmus_maximus
ENSG00000013016	EHD3	100	92.150	ENSSDUG00000010820	ehd3	100	92.150	Seriola_dumerili
ENSG00000013016	EHD3	100	90.467	ENSSLDG00000025510	ehd3	100	90.467	Seriola_lalandi_dorsalis
ENSG00000013016	EHD3	99	96.816	ENSSPUG00000014730	EHD3	99	96.816	Sphenodon_punctatus
ENSG00000013016	EHD3	100	91.589	ENSSPAG00000013275	ehd3	100	91.589	Stegastes_partitus
ENSG00000013016	EHD3	100	97.383	ENSSSCG00000035987	EHD3	100	97.383	Sus_scrofa
ENSG00000013016	EHD3	100	94.590	ENSTGUG00000004572	EHD3	100	94.590	Taeniopygia_guttata
ENSG00000013016	EHD3	100	91.589	ENSTRUG00000014338	ehd3	100	91.589	Takifugu_rubripes
ENSG00000013016	EHD3	99	91.557	ENSTNIG00000010948	ehd3	99	91.557	Tetraodon_nigroviridis
ENSG00000013016	EHD3	99	96.987	ENSTBEG00000010371	EHD3	97	96.987	Tupaia_belangeri
ENSG00000013016	EHD3	100	93.645	ENSTTRG00000000167	EHD3	100	93.645	Tursiops_truncatus
ENSG00000013016	EHD3	100	98.131	ENSUAMG00000022243	EHD3	100	98.131	Ursus_americanus
ENSG00000013016	EHD3	99	97.378	ENSUMAG00000019931	EHD3	100	97.490	Ursus_maritimus
ENSG00000013016	EHD3	100	98.318	ENSVVUG00000007563	EHD3	98	98.318	Vulpes_vulpes
ENSG00000013016	EHD3	100	92.523	ENSXETG00000022070	ehd3	100	92.523	Xenopus_tropicalis
ENSG00000013016	EHD3	100	91.589	ENSXMAG00000025261	ehd3	100	91.589	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001881	receptor recycling	21791287.	IMP	Process
GO:0003676	nucleic acid binding	10673336.	TAS	Function
GO:0005509	calcium ion binding	-	IEA	Function
GO:0005515	protein binding	17233914.19864458.20489164.26226295.27189942.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005634	nucleus	10673336.	TAS	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0005829	cytosol	-	IEA	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0007596	blood coagulation	-	TAS	Process
GO:0010008	endosome membrane	-	TAS	Component
GO:0015031	protein transport	-	IEA	Process
GO:0020018	ciliary pocket membrane	25686250.	IDA	Component
GO:0030139	endocytic vesicle	-	IEA	Component
GO:0032456	endocytic recycling	17233914.	IDA	Process
GO:0034498	early endosome to Golgi transport	19139087.	IMP	Process
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component
GO:0051260	protein homooligomerization	17233914.	IPI	Process
GO:0055038	recycling endosome membrane	17233914.	IDA	Component
GO:0055117	regulation of cardiac muscle contraction	-	IEA	Process
GO:0060271	cilium assembly	25686250.	IMP	Process
GO:0072659	protein localization to plasma membrane	20489164.	IGI	Process
GO:0086036	regulation of cardiac muscle cell membrane potential	20489164.	IGI	Process
GO:0090160	Golgi to lysosome transport	19139087.	IMP	Process
GO:1901387	positive regulation of voltage-gated calcium channel activity	-	IEA	Process
GO:1903358	regulation of Golgi organization	19139087.	IMP	Process
GO:1903779	regulation of cardiac conduction	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Description

RBDs

Expression

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GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.