Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
ESCA | |||||||
ESCA | |||||||
ESCA | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
KIRC | |||||||
KIRP | |||||||
LAML | |||||||
LIHC | |||||||
LIHC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
OV | |||||||
OV | |||||||
PAAD | |||||||
READ | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
BRCA | |||
CESC | |||
COAD | |||
DLBC | |||
MESO | |||
PRAD | |||
SKCM | |||
STAD | |||
TGCT |
Cancer | P-value | Q-value |
---|---|---|
KIRC | ||
SARC | ||
UCS | ||
KIRP | ||
COAD | ||
BLCA | ||
READ | ||
LAML | ||
GBM | ||
LIHC | ||
CHOL | ||
LUAD |
PID | Title | Article | Time | Author | Doi |
---|---|---|---|---|---|
18279677 |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000467772 | GCLM-203 | 625 | - | - | - (aa) | - | - |
ENST00000615724 | GCLM-204 | 3008 | XM_011541261 | ENSP00000484507 | 252 (aa) | XP_011539563 | P48507 |
ENST00000370238 | GCLM-201 | 4857 | XM_017001056 | ENSP00000359258 | 274 (aa) | XP_016856545 | P48507 |
ENST00000462183 | GCLM-202 | 583 | - | - | - (aa) | - | - |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000023909 | GCLM | 100 | 96.350 | ENSMUSG00000028124 | Gclm | 100 | 96.350 | Mus_musculus |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0004357 | glutamate-cysteine ligase activity | 9841880. | IDA | Function |
GO:0004357 | glutamate-cysteine ligase activity | 16183645. | IMP | Function |
GO:0005829 | cytosol | 9895302. | NAS | Component |
GO:0005829 | cytosol | - | TAS | Component |
GO:0006534 | cysteine metabolic process | - | IEA | Process |
GO:0006536 | glutamate metabolic process | 9841880.9895302. | IDA | Process |
GO:0006750 | glutathione biosynthetic process | 21873635. | IBA | Process |
GO:0006750 | glutathione biosynthetic process | 10395918. | IDA | Process |
GO:0006750 | glutathione biosynthetic process | - | IEA | Process |
GO:0006750 | glutathione biosynthetic process | 12081989. | IMP | Process |
GO:0006750 | glutathione biosynthetic process | - | TAS | Process |
GO:0006979 | response to oxidative stress | 10395918. | IDA | Process |
GO:0007568 | aging | - | IEA | Process |
GO:0007584 | response to nutrient | - | IEA | Process |
GO:0008637 | apoptotic mitochondrial changes | - | IEA | Process |
GO:0014823 | response to activity | - | IEA | Process |
GO:0017109 | glutamate-cysteine ligase complex | 21873635. | IBA | Component |
GO:0017109 | glutamate-cysteine ligase complex | 9841880. | IDA | Component |
GO:0030234 | enzyme regulator activity | 21873635. | IBA | Function |
GO:0035226 | glutamate-cysteine ligase catalytic subunit binding | 9675072.9841880. | IPI | Function |
GO:0035229 | positive regulation of glutamate-cysteine ligase activity | 21873635. | IBA | Process |
GO:0035729 | cellular response to hepatocyte growth factor stimulus | - | IEA | Process |
GO:0035733 | hepatic stellate cell activation | - | IEA | Process |
GO:0042493 | response to drug | 9895302. | IDA | Process |
GO:0043524 | negative regulation of neuron apoptotic process | - | IEA | Process |
GO:0044344 | cellular response to fibroblast growth factor stimulus | - | IEA | Process |
GO:0044752 | response to human chorionic gonadotropin | - | IEA | Process |
GO:0046982 | protein heterodimerization activity | - | IEA | Function |
GO:0050880 | regulation of blood vessel size | 12975258. | IMP | Process |
GO:0051409 | response to nitrosative stress | - | IEA | Process |
GO:0051900 | regulation of mitochondrial depolarization | - | IEA | Process |
GO:0071333 | cellular response to glucose stimulus | - | IEA | Process |
GO:0071372 | cellular response to follicle-stimulating hormone stimulus | - | IEA | Process |
GO:0097069 | cellular response to thyroxine stimulus | - | IEA | Process |
GO:1990830 | cellular response to leukemia inhibitory factor | - | IEA | Process |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | - | IEA | Process |