EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27221498	Decreased Expression of EHD2 Promotes Tumor Metastasis and Indicates Poor Prognosis in Hepatocellular Carcinoma.	Dig Dis Sci	2016 Sep	Liu J	doi: 10.1007/s10620-016-4202-6
25758127	Decreased expression and prognostic role of EHD2 in human breast carcinoma: correlation with E-cadherin.	J Mol Histol	2015 Apr	Shi Y	doi: 10.1007/s10735-015-9614-7
25557791	Role of EHD2 in migration and invasion of human breast cancer cells.	Tumour Biol	2015 May	Yang X	doi: 10.1007/s13277-014-3011-9

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	47725921	Silent	rs202143335	I204I	0.38
BLCA	chr19	47725954	Silent	novel	R215R	0.43
BLCA	chr19	47725847	Missense_Mutation	novel	E180Q	0.1	MMR_HSR1
BLCA	chr19	47725911	Missense_Mutation	novel	S201L	0.32	MMR_HSR1
BLCA	chr19	47716987	Silent	rs781646087	L125L	0.21
BLCA	chr19	47741121	Missense_Mutation	rs772336133	E441K	0.13
BLCA	chr19	47741263	Missense_Mutation	NA	R488H	0.29
BLCA	chr19	47741229	Missense_Mutation	novel	V477L	0.16
BLCA	chr19	47741201	Silent	novel	L467L	0.19
BLCA	chr19	47740958	Silent	NA	L386L	0.42
BRCA	chr19	47741325	Missense_Mutation	novel	A509T	0.09
BRCA	chr19	47725975	Missense_Mutation	NA	D222E	0.18
BRCA	chr19	47736473	Silent	NA	A340A	0.19
BRCA	chr19	47726222	Nonsense_Mutation	NA	R305*	0.21
BRCA	chr19	47740914	Missense_Mutation	NA	H372Y	0.15
BRCA	chr19	47742867	3'UTR	novel		0.18
BRCA	chr19	47741138	Silent	novel	V446V	0.12
BRCA	chr19	47736409	Missense_Mutation	NA	P319L	0.23
CESC	chr19	47736375	Missense_Mutation	novel	A308T	0.12
CESC	chr19	47741121	Missense_Mutation	rs772336133	E441K	0.16
CESC	chr19	47742641	3'UTR	novel		0.54
CESC	chr19	47742769	3'UTR	novel		0.16
CESC	chr19	47716564	5'UTR	novel		0.34
CESC	chr19	47718561	Missense_Mutation	rs146188664	D153N	0.41	MMR_HSR1
CESC	chr19	47725832	Silent	NA	L175L	0.41
CESC	chr19	47726129	Missense_Mutation	novel	E274K	0.2
COAD	chr19	47741360	Silent	rs200296704	H520H	0.4
COAD	chr19	47736410	Silent	rs369898716	P319P	0.36
COAD	chr19	47736476	Missense_Mutation	novel	K341N	0.3
COAD	chr19	47716666	Silent	novel	I18I	0.39
COAD	chr19	47725844	Missense_Mutation	novel	A179T	0.21	MMR_HSR1
COAD	chr19	47740995	Nonsense_Mutation	novel	Q399*	0.26
COAD	chr19	47740965	Missense_Mutation	rs373126567	D389N	0.27
COAD	chr19	47726071	Silent	rs775008579	I254I	0.35
COAD	chr19	47726046	Missense_Mutation	NA	T246M	0.43
COAD	chr19	47718560	Silent	novel	I152I	0.25
COAD	chr19	47725859	Missense_Mutation	NA	L184F	0.19	MMR_HSR1
COAD	chr19	47741360	Silent	rs200296704	H520H	0.21
COAD	chr19	47725844	Missense_Mutation	novel	A179T	0.49	MMR_HSR1
COAD	chr19	47726174	Missense_Mutation	novel	A289T	0.3
COAD	chr19	47716876	Frame_Shift_Del	NA	*P90Lfs76**	0.35	MMR_HSR1
COAD	chr19	47725917	Missense_Mutation	NA	A203D	0.3	MMR_HSR1
COAD	chr19	47741294	Silent	rs570148430	D498D	0.22
COAD	chr19	47716805	Missense_Mutation	rs757488835	G65S	0.27	MMR_HSR1
COAD	chr19	47725835	Missense_Mutation	novel	R176C	0.22	MMR_HSR1
COAD	chr19	47725926	Missense_Mutation	NA	A206V	0.07	MMR_HSR1
COAD	chr19	47741295	Missense_Mutation	rs781614465	G499S	0.18
COAD	chr19	47716864	Silent	rs147896380	P84P	0.33
ESCA	chr19	47716668	Missense_Mutation	rs371409023	R19H	0.1
ESCA	chr19	47740979	Silent	rs146746938	L393L	0.27
GBM	chr19	47726177	Missense_Mutation	novel	A290T	0.68
GBM	chr19	47716806	Missense_Mutation	novel	G65A	0.33	MMR_HSR1
HNSC	chr19	47716978	Silent	novel	F122F	0.2
HNSC	chr19	47741260	Missense_Mutation	novel	G487V	0.42
HNSC	chr19	47741030	Frame_Shift_Del	NA	*G412Afs35**	0.14
HNSC	chr19	47726071	Silent	rs775008579	I254I	0.43
HNSC	chr19	47741383	Missense_Mutation	rs749802863	R528H	0.48
LAML	chr19	47726183	Missense_Mutation	rs774957397	R292C	0.38
LGG	chr19	47725851	Missense_Mutation	rs751209627	R181H	0.16	MMR_HSR1
LGG	chr19	47741325	Missense_Mutation	novel	A509T	0.29
LIHC	chr19	47716710	Missense_Mutation	novel	L33Q	0.28
LIHC	chr19	47741162	Silent	rs138874482	D454D	0.31
LIHC	chr19	47718581	Silent	rs369297316	S159S	0.4
LIHC	chr19	47726052	Missense_Mutation	NA	E248V	0.15
LIHC	chr19	47736473	Silent	rs536783884	A340A	0.15
LUAD	chr19	47716757	Missense_Mutation	novel	A49S	0.27
LUAD	chr19	47741209	Missense_Mutation	novel	S470F	0.19
LUAD	chr19	47736504	Frame_Shift_Del	novel	*D352Tfs12**	0.43
LUAD	chr19	47740919	Silent	novel	S373S	0.21
LUAD	chr19	47741292	Missense_Mutation	rs747209337	D498N	0.27
LUSC	chr19	47716612	5'UTR	rs369298767		0.5
LUSC	chr19	47741140	Missense_Mutation	novel	T447N	0.2
LUSC	chr19	47718589	Missense_Mutation	NA	K162M	1	MMR_HSR1
LUSC	chr19	47725899	Missense_Mutation	novel	S197W	0.07	MMR_HSR1
LUSC	chr19	47741259	Missense_Mutation	novel	G487W	0.46
LUSC	chr19	47740990	Missense_Mutation	novel	L397P	0.5
LUSC	chr19	47740991	Silent	novel	L397L	0.49
LUSC	chr19	47740915	Missense_Mutation	novel	H372L	0.27
OV	chr19	47725844	Missense_Mutation	NA	A179S	0.4	MMR_HSR1
OV	chr19	47736441	Missense_Mutation	novel	Q330E	0.06
OV	chr19	47740901	Missense_Mutation	NA	D367E	0.51
PAAD	chr19	47741241	Missense_Mutation	novel	L481F	0.05
PCPG	chr19	47736524	Silent	novel	Q357Q	0.41
PRAD	chr19	47716973	In_Frame_Del	novel	P121_F122del	0.19	MMR_HSR1
READ	chr19	47716757	Missense_Mutation	NA	A49T	0.67
READ	chr19	47725904	Missense_Mutation	rs776967729	E199K	0.41	MMR_HSR1
SARC	chr19	47716794	Missense_Mutation	novel	V61G	0.93	MMR_HSR1
SKCM	chr19	47740950	Missense_Mutation	rs149075256	E384K	0.16
SKCM	chr19	47716768	Missense_Mutation	NA	D52E	0.42
SKCM	chr19	47736485	Silent	rs766223992	L344L	0.39
SKCM	chr19	47716991	Missense_Mutation	NA	P127S	0.51	MMR_HSR1
SKCM	chr19	47725813	Splice_Region	NA	G168G	0.52
SKCM	chr19	47725843	Silent	NA	F178F	0.28
SKCM	chr19	47716733	Missense_Mutation	rs774772728	R41C	0.2
SKCM	chr19	47725843	Silent	NA	F178F	0.22
SKCM	chr19	47716966	Silent	NA	P118P	0.32
SKCM	chr19	47716957	Silent	rs545919028	V115V	0.23
SKCM	chr19	47716992	Missense_Mutation	NA	P127L	0.36	MMR_HSR1
SKCM	chr19	47736449	Silent	NA	I332I	0.33
SKCM	chr19	47716777	Silent	rs750209017	F55F	0.13
SKCM	chr19	47741362	Missense_Mutation	NA	G521E	0.29
STAD	chr19	47726063	Missense_Mutation	rs767063664	V252I	0.4
STAD	chr19	47740949	Silent	rs755568627	D383D	0.17
STAD	chr19	47741117	Silent	rs543104405	D439D	0.14
STAD	chr19	47716980	Missense_Mutation	rs780481751	R123H	0.3	MMR_HSR1
STAD	chr19	47716979	Missense_Mutation	rs745870470	R123C	0.25	MMR_HSR1
STAD	chr19	47740928	Silent	rs781623704	P376P	0.31
STAD	chr19	47725937	Missense_Mutation	novel	H210Y	0.3	MMR_HSR1
STAD	chr19	47741121	Missense_Mutation	rs772336133	E441K	0.28
STAD	chr19	47741410	Missense_Mutation	novel	R537H	0.56
STAD	chr19	47741263	Missense_Mutation	NA	R488H	0.25
STAD	chr19	47736421	Missense_Mutation	NA	G323V	0.13
STAD	chr19	47741030	Frame_Shift_Del	NA	*G412Afs35**	0.11
STAD	chr19	47716776	Missense_Mutation	NA	F55C	0.43
STAD	chr19	47740971	Missense_Mutation	rs775528505	A391T	0.39
STAD	chr19	47741263	Missense_Mutation	NA	R488H	0.27
STAD	chr19	47741295	Missense_Mutation	novel	G499C	0.27
STAD	chr19	47741029	Frame_Shift_Ins	novel	*A413Rfs3**	0.15
UCEC	chr19	47726071	Silent	rs775008579	I254I	0.36
UCEC	chr19	47736368	Splice_Site	NA	X306_splice	0.27
UCEC	chr19	47741201	Silent	novel	L467L	0.48
UCEC	chr19	47736472	Missense_Mutation	rs761441836	A340V	0.37
UCEC	chr19	47742758	3'UTR	novel		0.39
UCEC	chr19	47742916	3'UTR	rs148784303		0.39
UCEC	chr19	47743013	3'UTR	novel		0.33
UCEC	chr19	47741109	Missense_Mutation	novel	G437S	0.24
UCEC	chr19	47742736	3'UTR	novel		0.09
UCEC	chr19	47736375	Missense_Mutation	novel	A308T	0.53
UCEC	chr19	47736374	Silent	rs776110210	H307H	0.41
UCEC	chr19	47741082	Missense_Mutation	novel	D428N	0.6
UCEC	chr19	47726309	Intron	novel		0.27
UCEC	chr19	47716802	Missense_Mutation	novel	A64T	0.55	MMR_HSR1
UCEC	chr19	47718605	Splice_Region	rs368179494	R167R	0.23
UCEC	chr19	47725894	Silent	NA	E195E	0.14
UCEC	chr19	47726061	Missense_Mutation	NA	R251H	0.19
UCEC	chr19	47741263	Missense_Mutation	NA	R488H	0.19
UCEC	chr19	47716723	Missense_Mutation	novel	E37D	0.43
UCEC	chr19	47726223	Missense_Mutation	novel	R305Q	0.39
UCEC	chr19	47725828	Silent	rs553547501	A173A	0.1
UCEC	chr19	47716936	Silent	rs769257295	T108T	0.23
UCEC	chr19	47741081	Silent	NA	P427P	0.17
UCEC	chr19	47716668	Missense_Mutation	rs371409023	R19H	0.33
UCEC	chr19	47736450	Missense_Mutation	novel	L333I	0.3
UCEC	chr19	47742922	3'UTR	rs544048055		0.41
UCEC	chr19	47741300	Missense_Mutation	novel	M500I	0.39
UCEC	chr19	47743004	3'UTR	novel		0.35
UCEC	chr19	47736472	Missense_Mutation	rs761441836	A340V	0.39
UCEC	chr19	47741163	Missense_Mutation	novel	E455K	0.11
UCEC	chr19	47726011	Silent	novel	G234G	0.39
UCEC	chr19	47741319	Missense_Mutation	novel	A507T	0.29
UCEC	chr19	47742665	3'UTR	novel		0.49
UCEC	chr19	47736402	Missense_Mutation	NA	E317K	0.31
UCEC	chr19	47726020	Missense_Mutation	novel	M237I	0.39
UCEC	chr19	47718561	Missense_Mutation	rs146188664	D153N	0.48	MMR_HSR1
UCEC	chr19	47740899	Missense_Mutation	rs750624524	D367N	0.37
UCEC	chr19	47736459	Missense_Mutation	rs139276620	P336S	0.08
UCEC	chr19	47716847	Missense_Mutation	novel	L79M	0.14	MMR_HSR1
UCEC	chr19	47726027	Missense_Mutation	novel	L240M	0.24
UCEC	chr19	47736530	Missense_Mutation	novel	M359I	0.25
UCEC	chr19	47716676	Missense_Mutation	novel	T22A	0.36
UCEC	chr19	47716838	Nonsense_Mutation	novel	Q76*	0.37	MMR_HSR1
UCEC	chr19	47740944	Silent	NA	L382L	0.36
UCEC	chr19	47726098	Silent	rs767163876	L263L	0.26
UCEC	chr19	47740894	Missense_Mutation	novel	A365V	0.28
UCEC	chr19	47726025	Missense_Mutation	NA	A239V	0.38
UCEC	chr19	47736463	Missense_Mutation	NA	V337A	0.4
UCEC	chr19	47716777	Silent	rs750209017	F55F	0.15
UCEC	chr19	47740949	Silent	rs755568627	D383D	0.11
UCEC	chr19	47742879	3'UTR	novel		0.36
UCEC	chr19	47725894	Silent	NA	E195E	0.3
UCEC	chr19	47741287	Missense_Mutation	NA	D496G	0.11
UCEC	chr19	47742600	3'UTR	novel		0.5
UCEC	chr19	47742691	3'UTR	novel		0.42
UCEC	chr19	47716734	Missense_Mutation	rs369448629	R41H	0.42
UCEC	chr19	47726061	Missense_Mutation	NA	R251H	0.15
UCEC	chr19	47740927	Missense_Mutation	rs200177048	P376L	0.53
UCEC	chr19	47742897	3'UTR	novel		0.4

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0949	0.027508
KIRP	DEL	0.0486	0.054726
LUAD	DEL	0.2655	1.5526e-05
LUSC	DEL	0.2196	1.1877e-06
OV	DEL	0.4819	2.441e-17
PAAD	DEL	0.0924	0.035089
READ	DEL	0.097	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.2321	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0073	Kaplan-Meier Survival Analysis
STAD	0.0037	Kaplan-Meier Survival Analysis
MESO	0.0031	Kaplan-Meier Survival Analysis
ACC	0.023	Kaplan-Meier Survival Analysis
HNSC	0.009	Kaplan-Meier Survival Analysis
LUSC	0.05	Kaplan-Meier Survival Analysis
ESCA	0.018	Kaplan-Meier Survival Analysis
PAAD	0.025	Kaplan-Meier Survival Analysis
BLCA	0.001	Kaplan-Meier Survival Analysis
CESC	0.0071	Kaplan-Meier Survival Analysis
GBM	0.0071	Kaplan-Meier Survival Analysis
LIHC	0.046	Kaplan-Meier Survival Analysis
THCA	0.0034	Kaplan-Meier Survival Analysis
UVM	0.00013	Kaplan-Meier Survival Analysis
OV	0.021	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000024422 (Gene tree)
Gene ID: 30846
Gene Symbol: EHD2
Alias: PAST2
Full Name: EH domain containing 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 29,792 bases
Position: chr19:47,713,343-47,743,134
Accession: 3243
RBP type: canonical RBP
Summary: This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000263277	MMR_HSR1	PF01926.23	7.2e-07	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000596225	EHD2-204	538	-	ENSP00000471766	30 (aa)	-	M0R1B9
ENST00000540884	EHD2-203	1215	-	-	- (aa)	-	-
ENST00000538399	EHD2-202	1766	-	ENSP00000439036	407 (aa)	-	Q9NZN4
ENST00000263277	EHD2-201	3585	-	ENSP00000263277	543 (aa)	-	Q9NZN4
ENST00000602215	EHD2-205	234	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000024422's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04144	Endocytosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000024422's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000024422	EHD2	99	81.728	ENSAPOG00000012705	ehd2b	98	80.755	Acanthochromis_polyacanthus
ENSG00000024422	EHD2	99	65.764	ENSAPOG00000021608	-	97	66.730	Acanthochromis_polyacanthus
ENSG00000024422	EHD2	100	99.079	ENSAMEG00000015263	EHD2	100	99.079	Ailuropoda_melanoleuca
ENSG00000024422	EHD2	99	65.926	ENSACIG00000011074	-	99	65.000	Amphilophus_citrinellus
ENSG00000024422	EHD2	99	81.975	ENSAOCG00000006422	EHD2	98	81.132	Amphiprion_ocellaris
ENSG00000024422	EHD2	99	65.517	ENSAOCG00000002163	-	97	66.540	Amphiprion_ocellaris
ENSG00000024422	EHD2	99	81.975	ENSAPEG00000013956	ehd2b	98	81.132	Amphiprion_percula
ENSG00000024422	EHD2	99	65.025	ENSAPEG00000019382	-	97	66.160	Amphiprion_percula
ENSG00000024422	EHD2	98	65.337	ENSATEG00000004166	-	96	66.411	Anabas_testudineus
ENSG00000024422	EHD2	100	99.754	ENSANAG00000031077	EHD2	100	99.632	Aotus_nancymaae
ENSG00000024422	EHD2	99	80.494	ENSACLG00000021088	ehd2b	99	79.511	Astatotilapia_calliptera
ENSG00000024422	EHD2	99	64.444	ENSACLG00000005241	-	97	65.143	Astatotilapia_calliptera
ENSG00000024422	EHD2	99	71.776	ENSAMXG00000013748	ehd2a	95	72.316	Astyanax_mexicanus
ENSG00000024422	EHD2	100	98.771	ENSBTAG00000021191	EHD2	100	98.711	Bos_taurus
ENSG00000024422	EHD2	100	99.754	ENSCJAG00000011415	EHD2	100	99.632	Callithrix_jacchus
ENSG00000024422	EHD2	100	99.263	ENSCAFG00000004095	EHD2	100	98.899	Canis_familiaris
ENSG00000024422	EHD2	100	99.263	ENSCAFG00020000226	EHD2	100	99.263	Canis_lupus_dingo
ENSG00000024422	EHD2	100	98.527	ENSCHIG00000011896	EHD2	100	98.527	Capra_hircus
ENSG00000024422	EHD2	100	97.422	ENSCAPG00000007033	EHD2	100	97.422	Cavia_aperea
ENSG00000024422	EHD2	100	97.422	ENSCPOG00000026417	EHD2	100	97.422	Cavia_porcellus
ENSG00000024422	EHD2	100	99.754	ENSCCAG00000035777	EHD2	100	99.632	Cebus_capucinus
ENSG00000024422	EHD2	100	97.974	ENSCLAG00000001756	EHD2	100	97.974	Chinchilla_lanigera
ENSG00000024422	EHD2	100	99.816	ENSCSAG00000002930	EHD2	100	99.816	Chlorocebus_sabaeus
ENSG00000024422	EHD2	100	85.012	ENSCPBG00000009041	EHD2	100	82.320	Chrysemys_picta_bellii
ENSG00000024422	EHD2	100	99.816	ENSCANG00000040566	EHD2	100	99.816	Colobus_angolensis_palliatus
ENSG00000024422	EHD2	100	98.034	ENSCGRG00001018635	Ehd2	100	97.790	Cricetulus_griseus_chok1gshd
ENSG00000024422	EHD2	99	80.049	ENSCSEG00000007149	ehd2b	98	78.908	Cynoglossus_semilaevis
ENSG00000024422	EHD2	99	64.390	ENSCSEG00000001675	-	97	65.849	Cynoglossus_semilaevis
ENSG00000024422	EHD2	99	82.222	ENSCVAG00000002381	ehd2b	98	81.132	Cyprinodon_variegatus
ENSG00000024422	EHD2	99	65.271	ENSCVAG00000018998	-	97	65.970	Cyprinodon_variegatus
ENSG00000024422	EHD2	99	83.047	ENSDARG00000040362	ehd2b	98	81.955	Danio_rerio
ENSG00000024422	EHD2	99	68.627	ENSDARG00000035137	ehd2a	97	69.288	Danio_rerio
ENSG00000024422	EHD2	100	98.527	ENSDORG00000011700	Ehd2	100	98.527	Dipodomys_ordii
ENSG00000024422	EHD2	100	98.895	ENSECAG00000028265	EHD2	100	98.895	Equus_caballus
ENSG00000024422	EHD2	56	96.393	ENSEEUG00000000956	EHD2	100	96.393	Erinaceus_europaeus
ENSG00000024422	EHD2	99	67.079	ENSELUG00000019299	ehd2a	97	67.557	Esox_lucius
ENSG00000024422	EHD2	99	80.835	ENSELUG00000021876	ehd2b	98	80.451	Esox_lucius
ENSG00000024422	EHD2	100	98.527	ENSFCAG00000029117	EHD2	100	98.527	Felis_catus
ENSG00000024422	EHD2	100	97.543	ENSFDAG00000015675	EHD2	100	97.552	Fukomys_damarensis
ENSG00000024422	EHD2	99	81.481	ENSFHEG00000020637	ehd2b	98	80.943	Fundulus_heteroclitus
ENSG00000024422	EHD2	99	66.010	ENSFHEG00000002126	-	97	66.540	Fundulus_heteroclitus
ENSG00000024422	EHD2	98	64.356	ENSGMOG00000000211	-	97	65.217	Gadus_morhua
ENSG00000024422	EHD2	99	79.218	ENSGMOG00000013367	ehd2b	98	79.401	Gadus_morhua
ENSG00000024422	EHD2	100	78.133	ENSGALG00000036498	EHD2	100	77.901	Gallus_gallus
ENSG00000024422	EHD2	99	64.778	ENSGAFG00000004457	ehd2a	97	65.779	Gambusia_affinis
ENSG00000024422	EHD2	99	63.636	ENSGACG00000007320	-	97	64.326	Gasterosteus_aculeatus
ENSG00000024422	EHD2	99	80.247	ENSGACG00000013023	ehd2b	98	79.434	Gasterosteus_aculeatus
ENSG00000024422	EHD2	100	85.749	ENSGAGG00000022066	EHD2	100	82.873	Gopherus_agassizii
ENSG00000024422	EHD2	100	100.000	ENSGGOG00000002346	EHD2	100	100.000	Gorilla_gorilla
ENSG00000024422	EHD2	99	80.494	ENSHBUG00000009900	ehd2b	98	79.434	Haplochromis_burtoni
ENSG00000024422	EHD2	99	64.691	ENSHBUG00000008791	-	97	65.333	Haplochromis_burtoni
ENSG00000024422	EHD2	100	97.974	ENSHGLG00000017825	EHD2	100	97.974	Heterocephalus_glaber_female
ENSG00000024422	EHD2	100	97.974	ENSHGLG00100017344	EHD2	100	97.974	Heterocephalus_glaber_male
ENSG00000024422	EHD2	99	64.179	ENSHCOG00000012768	-	98	64.179	Hippocampus_comes
ENSG00000024422	EHD2	99	80.835	ENSHCOG00000017683	ehd2b	97	79.887	Hippocampus_comes
ENSG00000024422	EHD2	99	71.499	ENSIPUG00000024057	ehd2a	98	70.588	Ictalurus_punctatus
ENSG00000024422	EHD2	99	81.818	ENSIPUG00000000204	Ehd2	98	81.391	Ictalurus_punctatus
ENSG00000024422	EHD2	100	98.526	ENSJJAG00000008621	Ehd2	100	97.790	Jaculus_jaculus
ENSG00000024422	EHD2	99	64.778	ENSKMAG00000003332	-	97	65.209	Kryptolebias_marmoratus
ENSG00000024422	EHD2	99	81.728	ENSKMAG00000012447	ehd2b	98	80.755	Kryptolebias_marmoratus
ENSG00000024422	EHD2	99	79.856	ENSLBEG00000018343	ehd2b	98	79.336	Labrus_bergylta
ENSG00000024422	EHD2	99	65.602	ENSLBEG00000004961	-	97	66.603	Labrus_bergylta
ENSG00000024422	EHD2	79	89.286	ENSLACG00000018332	ehd2a	95	83.934	Latimeria_chalumnae
ENSG00000024422	EHD2	100	99.816	ENSMMUG00000040121	EHD2	100	99.816	Macaca_mulatta
ENSG00000024422	EHD2	99	65.764	ENSMAMG00000004890	-	97	66.730	Mastacembelus_armatus
ENSG00000024422	EHD2	99	64.444	ENSMZEG00005005247	-	97	65.143	Maylandia_zebra
ENSG00000024422	EHD2	99	80.494	ENSMZEG00005024162	ehd2b	98	79.434	Maylandia_zebra
ENSG00000024422	EHD2	100	97.789	ENSMAUG00000010317	Ehd2	100	97.606	Mesocricetus_auratus
ENSG00000024422	EHD2	100	96.685	ENSMICG00000005571	EHD2	100	96.685	Microcebus_murinus
ENSG00000024422	EHD2	100	98.034	ENSMOCG00000007010	Ehd2	100	97.238	Microtus_ochrogaster
ENSG00000024422	EHD2	98	64.090	ENSMMOG00000009001	-	97	64.981	Mola_mola
ENSG00000024422	EHD2	99	80.494	ENSMALG00000008756	ehd2b	98	79.623	Monopterus_albus
ENSG00000024422	EHD2	100	97.052	MGP_CAROLIEiJ_G0029219	Ehd2	100	100.000	Mus_caroli
ENSG00000024422	EHD2	100	97.052	ENSMUSG00000074364	Ehd2	100	100.000	Mus_musculus
ENSG00000024422	EHD2	100	97.297	MGP_PahariEiJ_G0021075	Ehd2	100	100.000	Mus_pahari
ENSG00000024422	EHD2	100	97.297	MGP_SPRETEiJ_G0030299	Ehd2	100	100.000	Mus_spretus
ENSG00000024422	EHD2	100	99.263	ENSMPUG00000004466	EHD2	100	99.079	Mustela_putorius_furo
ENSG00000024422	EHD2	100	99.017	ENSNGAG00000018699	Ehd2	100	98.527	Nannospalax_galili
ENSG00000024422	EHD2	99	64.691	ENSNBRG00000002925	ehd2a	99	63.904	Neolamprologus_brichardi
ENSG00000024422	EHD2	100	89.435	ENSMEUG00000000445	EHD2	100	90.110	Notamacropus_eugenii
ENSG00000024422	EHD2	100	97.790	ENSODEG00000006641	EHD2	100	97.790	Octodon_degus
ENSG00000024422	EHD2	99	64.373	ENSONIG00000005597	-	99	64.088	Oreochromis_niloticus
ENSG00000024422	EHD2	99	80.741	ENSONIG00000004051	ehd2b	98	79.623	Oreochromis_niloticus
ENSG00000024422	EHD2	99	81.481	ENSORLG00000002244	ehd2b	98	80.189	Oryzias_latipes
ENSG00000024422	EHD2	98	64.339	ENSORLG00000012013	-	96	64.627	Oryzias_latipes
ENSG00000024422	EHD2	98	64.339	ENSORLG00020013250	-	96	64.627	Oryzias_latipes_hni
ENSG00000024422	EHD2	99	81.235	ENSORLG00020017051	ehd2b	98	80.000	Oryzias_latipes_hni
ENSG00000024422	EHD2	98	64.589	ENSORLG00015021510	-	96	64.818	Oryzias_latipes_hsok
ENSG00000024422	EHD2	99	81.481	ENSORLG00015005729	ehd2	98	80.189	Oryzias_latipes_hsok
ENSG00000024422	EHD2	98	64.589	ENSOMEG00000003975	-	96	64.818	Oryzias_melastigma
ENSG00000024422	EHD2	99	81.481	ENSOMEG00000001261	ehd2b	98	81.132	Oryzias_melastigma
ENSG00000024422	EHD2	100	98.895	ENSOGAG00000033142	EHD2	100	98.895	Otolemur_garnettii
ENSG00000024422	EHD2	97	97.148	ENSOARG00000011391	EHD2	89	97.148	Ovis_aries
ENSG00000024422	EHD2	100	96.317	ENSPPAG00000039669	EHD2	100	96.317	Pan_paniscus
ENSG00000024422	EHD2	100	98.771	ENSPPRG00000008148	EHD2	100	98.711	Panthera_pardus
ENSG00000024422	EHD2	100	98.771	ENSPTIG00000018608	EHD2	100	98.711	Panthera_tigris_altaica
ENSG00000024422	EHD2	100	99.632	ENSPTRG00000011214	EHD2	100	99.632	Pan_troglodytes
ENSG00000024422	EHD2	100	99.632	ENSPTRG00000046930	EHD2	100	99.632	Pan_troglodytes
ENSG00000024422	EHD2	100	99.816	ENSPANG00000026345	EHD2	100	99.816	Papio_anubis
ENSG00000024422	EHD2	99	82.222	ENSPKIG00000013262	EHD2	99	80.258	Paramormyrops_kingsleyae
ENSG00000024422	EHD2	99	78.818	ENSPKIG00000016765	ehd2a	99	76.796	Paramormyrops_kingsleyae
ENSG00000024422	EHD2	99	64.951	ENSPMGG00000013285	-	97	65.530	Periophthalmus_magnuspinnatus
ENSG00000024422	EHD2	99	80.741	ENSPMGG00000015379	ehd2b	99	80.337	Periophthalmus_magnuspinnatus
ENSG00000024422	EHD2	100	94.103	ENSPCIG00000016714	EHD2	100	93.773	Phascolarctos_cinereus
ENSG00000024422	EHD2	99	82.222	ENSPFOG00000011756	ehd2b	98	81.698	Poecilia_formosa
ENSG00000024422	EHD2	99	63.300	ENSPFOG00000012774	-	96	64.639	Poecilia_formosa
ENSG00000024422	EHD2	99	63.547	ENSPLAG00000000301	-	97	64.829	Poecilia_latipinna
ENSG00000024422	EHD2	99	82.469	ENSPLAG00000020534	ehd2b	98	81.887	Poecilia_latipinna
ENSG00000024422	EHD2	99	63.793	ENSPMEG00000024037	-	97	65.019	Poecilia_mexicana
ENSG00000024422	EHD2	99	82.222	ENSPMEG00000008030	ehd2b	98	81.698	Poecilia_mexicana
ENSG00000024422	EHD2	99	63.300	ENSPREG00000017608	ehd2a	97	64.639	Poecilia_reticulata
ENSG00000024422	EHD2	99	82.222	ENSPREG00000016332	ehd2b	98	81.887	Poecilia_reticulata
ENSG00000024422	EHD2	100	99.816	ENSPPYG00000010180	EHD2	90	99.816	Pongo_abelii
ENSG00000024422	EHD2	56	98.033	ENSPCAG00000007707	EHD2	100	98.033	Procavia_capensis
ENSG00000024422	EHD2	100	98.711	ENSPCOG00000010027	EHD2	100	98.711	Propithecus_coquereli
ENSG00000024422	EHD2	100	93.923	ENSPVAG00000014670	EHD2	100	93.923	Pteropus_vampyrus
ENSG00000024422	EHD2	99	80.494	ENSPNYG00000007864	ehd2b	98	79.434	Pundamilia_nyererei
ENSG00000024422	EHD2	99	64.444	ENSPNYG00000009593	-	97	65.143	Pundamilia_nyererei
ENSG00000024422	EHD2	99	81.311	ENSPNAG00000026764	ehd2b	98	80.669	Pygocentrus_nattereri
ENSG00000024422	EHD2	99	72.549	ENSPNAG00000016978	ehd2a	97	71.719	Pygocentrus_nattereri
ENSG00000024422	EHD2	99	82.512	ENSPNAG00000026560	ehd2b	98	81.579	Pygocentrus_nattereri
ENSG00000024422	EHD2	100	97.789	ENSRNOG00000011346	Ehd2	100	97.053	Rattus_norvegicus
ENSG00000024422	EHD2	100	99.816	ENSRBIG00000035965	EHD2	100	99.816	Rhinopithecus_bieti
ENSG00000024422	EHD2	100	99.816	ENSRROG00000043148	EHD2	100	99.816	Rhinopithecus_roxellana
ENSG00000024422	EHD2	100	99.263	ENSSBOG00000025594	EHD2	100	99.263	Saimiri_boliviensis_boliviensis
ENSG00000024422	EHD2	90	73.747	ENSSFOG00015006753	ehd2a	95	81.638	Scleropages_formosus
ENSG00000024422	EHD2	99	82.020	ENSSFOG00015023056	ehd2	100	79.336	Scleropages_formosus
ENSG00000024422	EHD2	99	65.764	ENSSMAG00000020341	-	97	67.110	Scophthalmus_maximus
ENSG00000024422	EHD2	99	80.000	ENSSMAG00000020558	ehd2b	98	79.434	Scophthalmus_maximus
ENSG00000024422	EHD2	99	66.502	ENSSDUG00000020042	-	97	67.823	Seriola_dumerili
ENSG00000024422	EHD2	99	81.481	ENSSDUG00000000141	ehd2b	98	80.755	Seriola_dumerili
ENSG00000024422	EHD2	99	81.481	ENSSLDG00000005368	ehd2b	98	80.755	Seriola_lalandi_dorsalis
ENSG00000024422	EHD2	99	66.995	ENSSLDG00000008515	-	97	67.681	Seriola_lalandi_dorsalis
ENSG00000024422	EHD2	100	83.824	ENSSPUG00000004401	EHD2	100	81.768	Sphenodon_punctatus
ENSG00000024422	EHD2	99	65.271	ENSSPAG00000006737	-	97	66.540	Stegastes_partitus
ENSG00000024422	EHD2	99	81.481	ENSSPAG00000018164	ehd2b	98	80.566	Stegastes_partitus
ENSG00000024422	EHD2	100	99.263	ENSSSCG00000023371	EHD2	100	99.079	Sus_scrofa
ENSG00000024422	EHD2	99	80.693	ENSTRUG00000010128	ehd2b	98	79.773	Takifugu_rubripes
ENSG00000024422	EHD2	99	81.235	ENSTNIG00000016284	ehd2b	97	80.377	Tetraodon_nigroviridis
ENSG00000024422	EHD2	100	97.790	ENSTTRG00000011850	EHD2	100	97.790	Tursiops_truncatus
ENSG00000024422	EHD2	100	99.263	ENSUAMG00000028253	EHD2	100	99.263	Ursus_americanus
ENSG00000024422	EHD2	50	98.897	ENSUMAG00000023829	-	74	98.897	Ursus_maritimus
ENSG00000024422	EHD2	100	99.263	ENSVVUG00000023369	EHD2	88	99.263	Vulpes_vulpes
ENSG00000024422	EHD2	100	82.801	ENSXETG00000002783	ehd2	100	80.295	Xenopus_tropicalis
ENSG00000024422	EHD2	99	64.532	ENSXCOG00000012882	-	98	65.209	Xiphophorus_couchianus
ENSG00000024422	EHD2	99	82.469	ENSXCOG00000008602	ehd2b	99	80.591	Xiphophorus_couchianus
ENSG00000024422	EHD2	99	64.373	ENSXMAG00000010771	ehd2a	97	65.465	Xiphophorus_maculatus
ENSG00000024422	EHD2	99	82.222	ENSXMAG00000029134	ehd2b	98	81.509	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003676	nucleic acid binding	10673336.	TAS	Function
GO:0005509	calcium ion binding	-	IEA	Function
GO:0005515	protein binding	17233914.25588833.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005634	nucleus	10673336.	TAS	Component
GO:0005829	cytosol	-	ISS	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0005886	plasma membrane	-	ISS	Component
GO:0005901	caveola	24013648.	IDA	Component
GO:0006897	endocytosis	-	IEA	Process
GO:0007596	blood coagulation	-	TAS	Process
GO:0010008	endosome membrane	-	TAS	Component
GO:0015630	microtubule cytoskeleton	-	IDA	Component
GO:0016787	hydrolase activity	-	IEA	Function
GO:0019898	extrinsic component of membrane	-	ISS	Component
GO:0019904	protein domain specific binding	-	IEA	Function
GO:0030866	cortical actin cytoskeleton organization	-	IEA	Process
GO:0032456	endocytic recycling	17233914.	IGI	Process
GO:0042802	identical protein binding	-	IEA	Function
GO:0045171	intercellular bridge	-	IDA	Component
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component
GO:0055038	recycling endosome membrane	17233914.	IDA	Component
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:0072659	protein localization to plasma membrane	-	ISS	Process
GO:0097320	plasma membrane tubulation	-	ISS	Process
GO:1901741	positive regulation of myoblast fusion	-	ISS	Process
GO:2001137	positive regulation of endocytic recycling	-	ISS	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.