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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
21664858Significance of tumor satellite variables in reflecting the epithelial-mesenchymal transition of tongue cancer.Oral Oncol2011 AugYang TLdoi: 10.1016/j.oraloncology.2011.04.006
20358301The clinical significance of vimentin-expressing gastric cancer cells in bone marrow.Ann Surg Oncol2010 SepIwatsuki Mdoi: 10.1245/s10434-010-1041-0
28592120Downregulated vimentin and upregulated E-cadherin in T1 stage non-small-cell lung cancer: does it suggest a mesenchymal-epithelial transition?Neoplasma2017Luo Tdoi: 10.4149/neo_2017_506.
22340393Vimentin significantly promoted gallbladder carcinoma metastasis.Chin Med J (Engl)2011 DecDong P-
22766839Tumor suppressive microRNA138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma.Int J Oncol2012 SepYamasaki Tdoi: 10.3892/ijo.2012.1543
18632620Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells.Cancer Res2008 Jul 15Whipple RAdoi: 10.1158/0008-5472.CAN-07-6589.
18985821Solitary fibrous tumor of the liver expressing CD34 and vimentin: a case report.World J Gastroenterol2008 Oct 28Korkolis DP-
26045832Expression of E-cadherin and vimentin in oral squamous cell carcinoma.Int J Clin Exp Pathol2015 Mar 1Zhou J-
26160837Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition.Oncotarget2015 Sep 15Wang TH-
26702618The number of polyploid giant cancer cells and epithelial-mesenchymal transition-related proteins are associated with invasion and metastasis in human breast cancer.J Exp Clin Cancer Res2015 Dec 24Fei Fdoi: 10.1186/s13046-015-0277-8.
27506606Impact of Expression of Vimentin and Axl in Breast Cancer.Clin Breast Cancer2016 DecTanaka Kdoi: 10.1016/j.clbc.2016.06.015
28225793Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients.PLoS One2017 Feb 22Dmello Cdoi: 10.1371/journal.pone.0172559
25075038Serum vimentin methylation as a potential marker for colorectal cancer.Anticancer Res2014 AugShirahata A-
12727854Overexpression of vimentin: role in the invasive phenotype in an androgen-independent model of prostate cancer.Cancer Res2003 May 1Singh S-
22236966HIPK2 downregulates vimentin and inhibits breast cancer cell invasion.Cancer Biol Ther2012 Feb 15Nodale Cdoi: 10.4161/cbt.13.4.18694
23056278Diagnosis of bladder cancer recurrence based on urinary levels of EOMES, HOXA9, POU4F2, TWIST1, VIM, and ZNF154 hypermethylation.PLoS One2012Reinert Tdoi: 10.1371/journal.pone.0046297
24387004Vimentin as an integral regulator of cell adhesion and endothelial sprouting.Microcirculation2014 MayDave JMdoi: 10.1111/micc.12111.
23614934A mutation in the 5' untranslated region of the BRCA1 gene in sporadic breast cancer causes downregulation of translation efficiency.J Int Med Res2007 Jul-AugWang J-
23224145MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion.Breast Cancer Res Treat2013 JanBockhorn Jdoi: 10.1007/s10549-012-2346-4
24447545RUNX3 regulates vimentin expression via miR-30a during epithelial-mesenchymal transition in gastric cancer cells.J Cell Mol Med2014 AprLiu Zdoi: 10.1111/jcmm.12209
23682784In vitro and in vivo effects of phenethyl isothiocyanate treatment on vimentin protein expression in cancer cells.Nutr Cancer2013Sakao Kdoi: 10.1080/01635581.2013.785002.
18464297Vimentin affects the mobility and invasiveness of prostate cancer cells.Cell Biochem Funct2008 Sep-OctZhao Ydoi: 10.1002/cbf.1478.
26819207Twist may be associated with invasion and metastasis of hypoxic NSCLC cells.Tumour Biol2016 JulWei Ldoi: 10.1007/s13277-016-4896-2
21327330Vimentin expression is associated with decreased survival in gastric cancer.Oncol Rep2011 MayOtsuki Sdoi: 10.3892/or.2011.1185
12750294Transactivation of vimentin by beta-catenin in human breast cancer cells.Cancer Res2003 May 15Gilles C-
27075696Liprin-α1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery.Sci Rep2016 Apr 14Pehkonen Hdoi: 10.1038/srep24486.
20975101Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples.Clin Cancer Res2010 Dec 1Costa VLdoi: 10.1158/1078-0432.CCR-10-1312
21187483Detection of vimentin (VIM) methylation in the serum of colorectal cancer patients.Anticancer Res2010 DecShirahata A-
25278713Negative methylation status of vimentin predicts improved prognosis in pancreatic carcinoma.World J Gastroenterol2014 Sep 28Zhou YFdoi: 10.3748/wjg.v20.i36.13172.
24858039Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity.Oncogene2015 Apr 9Havel LSdoi: 10.1038/onc.2014.123
22221700Significance of E-cadherin, β-catenin, and vimentin expression as postoperative prognosis indicators in cervical squamous cell carcinoma.Hum Pathol2012 AugCheng Ydoi: 10.1016/j.humpath.2011.08.025
22886823Dysregulated expression of Slug, vimentin, and E-cadherin correlates with poor clinical outcome in patients with basal-like breast cancer.J Surg Oncol2013 FebLiu Tdoi: 10.1002/jso.23240
24139214P-cadherin and vimentin are useful basal markers in breast cancers.Hum Pathol2013 DecTsang JYdoi: 10.1016/j.humpath.2013.07.029
23239149Vimentin DNA methylation predicts survival in breast cancer.Breast Cancer Res Treat2013 JanUlirsch Jdoi: 10.1007/s10549-012-2353-5
20422486[Effect of JAK2/STAT3/vimentin signaling pathway on proliferation and migration of human colon cancer cells].Zhonghua Wei Chang Wai Ke Za Zhi2010 AprXu JH-
26567912Down-regulation of MicroRNAs (MiRs) 203, 887, 3619 and 182 Prevents Vimentin-triggered, Phospholipase D (PLD)-mediated Cancer Cell Invasion.J Biol Chem2016 Jan 8Fite Kdoi: 10.1074/jbc.M115.686006
27048119Role of TWIST2, E-cadherin and Vimentin in epithelial ovarian carcinogenesis and prognosis and their interaction in cancer progression.Eur J Gynaecol Oncol2016Li X-
21442485[Clinical significance of signal transduction and activators of transcription 3, E-cadherin and vimentin in colon cancer].Zhonghua Wei Chang Wai Ke Za Zhi2011 MarZhang C-
19617759Stool methylation-specific polymerase chain reaction assay for the detection of colorectal neoplasia in Korean patients.Dis Colon Rectum2009 AugBaek YHdoi: 10.1007/DCR.0b013e3181a79533.
17585878Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion.Biochem Biophys Res Commun2007 Aug 17McInroy L-
24001454Increased expression of Slug and Vimentin as novel predictive biomarkers for lymph node metastasis and poor prognosis in colorectal cancer.Carcinogenesis2013 NovToiyama Ydoi: 10.1093/carcin/bgt282
22251609Detection of hypermethylated vimentin in urine of patients with colorectal cancer.J Mol Diagn2012 Mar-AprSong BPdoi: 10.1016/j.jmoldx.2011.12.003
27069130Vimentin Regulates Invasiveness and Is a Poor Prognostic Marker in Non-small Cell Lung Cancer.Anticancer Res2016 AprTadokoro A-
22476851MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer.Breast Cancer Res Treat2012 AugCheng CWdoi: 10.1007/s10549-012-2034-4
28341124Tenascin-C is a potential cancer-associated fibroblasts marker and predicts poor prognosis in prostate cancer.Biochem Biophys Res Commun2017 May 6Ni WDdoi: 10.1016/j.bbrc.2017.03.021
28373440Epithelial-Mesenchymal Transition in Non Small-cell Lung Cancer.Anticancer Res2017 AprTsoukalas N-
27163529Janus kinases and Src family kinases in the regulation of EGF-induced vimentin expression in MDA-MB-468 breast cancer cells.Int J Biochem Cell Biol2016 JulStewart TAdoi: 10.1016/j.biocel.2016.05.007
27932314TIS21/BTG2 inhibits doxorubicin-induced stress fiber-vimentin networks via Nox4-ROS-ABI2-DRF-linked signal cascade.Cell Signal2017 JanLim IKdoi: 10.1016/j.cellsig.2016.12.001
28771721The ubiquitin ligase TRIM56 inhibits ovarian cancer progression by targeting vimentin.J Cell Physiol2018 MarZhao Ldoi: 10.1002/jcp.26114
27363026Lung cancer exosomes as drivers of epithelial mesenchymal transition.Oncotarget2016 Aug 23Rahman MAdoi: 10.18632/oncotarget.10243.
27322682Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.Oncotarget2016 Jul 19Huo Ydoi: 10.18632/oncotarget.9970.
28611349Stromal Expression of Vimentin Predicts the Clinical Outcome of Stage II Colorectal Cancer for High-Risk Patients.Med Sci Monit2017 Jun 14Liu LG-
29257346miR-373 suppresses gastric cancer metastasis by downregulating vimentin.Mol Med Rep2018 MarShi Ydoi: 10.3892/mmr.2017.8291
29767267HDAC inhibitors, trichostatin A and valproic acid, increase Ecadherin and vimentin expression but inhibit migration and invasion of cholangiocarcinoma cells.Oncol Rep2018 JulWang JHdoi: 10.3892/or.2018.6441
30078472Vimentin immunohistochemical expression as a prognostic factor in gastric cancer: A meta-analysis.Pathol Res Pract2018 SepYin Sdoi: 10.1016/j.prp.2018.07.014
29956814Ecadherin is downregulated by microenvironmental changes in pancreatic cancer and induces EMT.Oncol Rep2018 SepWang Wdoi: 10.3892/or.2018.6528
29401610An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells.FASEB J2018 MayTrogden KPdoi: 10.1096/fj.201700663R
30189187Aberrant expression of vimentin predisposes oral premalignant lesion derived cells towards transformation.Exp Mol Pathol2018 DecDmello Cdoi: 10.1016/j.yexmp.2018.08.010
30408551EZH2-mediated epigenetic suppression of EphB3 inhibits gastric cancer proliferation and metastasis by affecting E-cadherin and vimentin expression.Gene2019 Feb 20Zhao Kdoi: 10.1016/j.gene.2018.11.015
30562753FOXD1 Promotes Cell Growth and Metastasis by Activation of Vimentin in NSCLC.Cell Physiol Biochem2018Li Ddoi: 10.1159/000495962
30399492Extracellular vimentin modulates human dendritic cell activation.Mol Immunol2018 DecYu MBdoi: 10.1016/j.molimm.2018.09.017

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
ACCchr1017233788Missense_MutationnovelA247P0.37
BLCAchr1017235885SilentnovelL423L0.42
BLCAchr1017235885SilentnovelL423L0.13
BLCAchr1017235292In_Frame_DelnovelR378_H379del0.2
BLCAchr1017235195SilentNAR345R0.28
BLCAchr1017235379Missense_MutationNAE407K0.25
BLCAchr1017233612Missense_Mutationrs762391438R217H0.4
BLCAchr1017234806SilentNAA332A0.09
BLCAchr1017229571Missense_Mutationrs11545553R50H0.32
BLCAchr1017233883Missense_MutationnovelS278R0.24
BLCAchr1017235346Missense_MutationNAE396Q0.21
BLCAchr1017233817Silentrs377349430I256I0.41
BLCAchr1017229445Missense_MutationnovelS8L0.23
BRCAchr1017230671Missense_MutationnovelQ195H0.13
BRCAchr1017229828Missense_MutationnovelE136Q0.07
BRCAchr1017236369Missense_MutationNAR450T0.29
BRCAchr1017233623Missense_MutationNAE221K0.14
CESCchr10172374803'UTRnovel0.36
CESCchr1017229881Missense_MutationNAE153D0.4
CESCchr1017236317Silentrs768266467L433L0.17
COADchr10172373213'UTRnovel0.29
COADchr1017229633Missense_MutationnovelR71W0.4
COADchr1017233590Missense_MutationnovelV210I0.21
COADchr1017229827SilentnovelL135L0.12
COADchr1017230656SilentNAQ190Q0.36
COADchr1017234738Missense_MutationNAR310C0.13
COADchr1017236293Splice_SiteNAX425_splice0.09
COADchr10172375303'UTRnovel0.33
ESCAchr1017233913Missense_MutationnovelE288D0.59
ESCAchr1017235329Missense_MutationnovelK390T0.2
ESCAchr10172375303'UTRnovel1
GBMchr1017229705Missense_MutationnovelE95Q0.35
GBMchr1017234711Missense_MutationnovelA301T0.2
HNSCchr1017233593Missense_MutationnovelD211H0.17
HNSCchr1017236317Silentrs768266467L433L0.11
HNSCchr1017234721Missense_Mutationrs552165238R304Q0.52
HNSCchr1017233623Missense_MutationnovelE221Q0.43
HNSCchr1017229592Missense_Mutationrs749931833P57L0.16
HNSCchr1017236349SilentnovelL443L0.36
HNSCchr1017235252SilentnovelR364R0.14
HNSCchr1017235253SilentnovelL365L0.14
KIRCchr1017235298Missense_MutationNAL380F0.17
KIRPchr1017234733Missense_MutationNAA308G0.15
KIRPchr1017236346SilentNAL442L0.41
LIHCchr10172374203'UTRnovel0.67
LIHCchr1017235886Missense_MutationNAR424W0.45
LIHCchr1017233584Splice_Regionnovel0.31
LIHCchr1017229487Missense_MutationnovelS22I0.43
LIHCchr1017229664Missense_MutationNAQ81L0.35
LIHCchr1017235864SilentNAP416P0.39
LIHCchr10172373463'UTRnovel0.32
LUADchr1017234750Nonsense_MutationNAQ314*0.66
LUADchr1017229860SilentnovelL146L0.36
LUADchr1017229974SilentNAR184R0.7
LUADchr1017233584Splice_Regionnovel0.24
LUADchr1017233635Nonsense_MutationNAE225*0.44
LUADchr1017233677Missense_Mutationrs748255267E239K0.15
LUADchr1017233824Missense_MutationnovelD259Y0.1
LUADchr10172293945'UTRrs7607505530.48
LUSCchr1017236316SilentnovelP432P0.44
LUSCchr1017233779Missense_MutationNAE244K0.19
LUSCchr1017236304SilentNAL428L0.27
LUSCchr1017236305Missense_MutationNAD429Y0.27
LUSCchr1017234804Missense_MutationNAA332S0.09
LUSCchr1017233679SilentnovelE239E0.23
LUSCchr1017233868SilentNAR273R0.77
LUSCchr1017229467Missense_MutationNAF15L0.32
LUSCchr10172294225'UTRnovel0.44
LUSCchr1017235853SilentnovelL413L0.12
LUSCchr1017233627Missense_MutationnovelR222L0.56
LUSCchr1017233770Missense_MutationNAE241K0.19
LUSCchr1017229982Missense_MutationNAE187G0.33
LUSCchr1017229931Missense_MutationnovelR170L0.28
OVchr1017235379Missense_MutationNAE407K0.1
OVchr1017235863Missense_MutationnovelP416L0.15
OVchr1017235251Missense_MutationnovelR364L0.03
OVchr1017233896Missense_MutationnovelN283D0.4
OVchr1017230694Missense_MutationnovelL203Q0.13
OVchr1017234769Missense_Mutationrs371431143R320Q0.14
PAADchr1017233681Splice_SitenovelX241_splice0.04
PAADchr1017234773SilentnovelR321R0.15
PAADchr1017235378SilentnovelG406G0.18
PRADchr1017229520Missense_MutationnovelT33M0.38
READchr10172373793'UTRnovel0.5
SARCchr10172293785'UTRnovel0.55
SKCMchr1017235176Missense_MutationnovelS339F0.4
SKCMchr1017236315Missense_MutationNAP432L0.22
SKCMchr1017233605SilentnovelL215L0.41
SKCMchr1017233908Missense_MutationnovelA287T0.29
SKCMchr1017233650Missense_MutationnovelE230K0.28
SKCMchr1017235177SilentnovelS339S0.36
SKCMchr1017229983Splice_RegionnovelE187E0.44
SKCMchr1017229962Silentrs778785495E180E0.29
SKCMchr1017234784Missense_MutationNAS325F0.14
SKCMchr1017229887SilentnovelR155R0.17
SKCMchr1017235875Missense_MutationNAS420F0.32
SKCMchr1017229888Missense_Mutationrs747904058E156K0.22
SKCMchr1017234786Missense_MutationNAL326F0.43
SKCMchr1017229936Missense_MutationNAE172K0.22
SKCMchr1017229887SilentnovelR155R0.12
SKCMchr1017229888Missense_Mutationrs747904058E156K0.17
SKCMchr1017229485Silentrs765009320A21A0.47
STADchr1017234694Missense_Mutationrs747735685F295S0.28
STADchr1017234731Silentrs770500248D307D0.07
STADchr1017229881SilentNAE153E0.5
STADchr1017235878Missense_MutationNAL421P0.15
STADchr1017236321Missense_MutationNAV434A0.35
STADchr1017235207Missense_MutationNAE349D0.24
STADchr1017235329Missense_MutationnovelK390T0.08
STADchr1017233858Missense_MutationNAR270H0.46
STADchr1017229776SilentnovelI118I0.36
STADchr1017234766Missense_MutationNAY319C0.26
STADchr1017235166Splice_Regionnovel0.35
STADchr1017234791SilentNAT327T0.31
STADchr1017233846Missense_Mutationrs150878383T266M0.33
STADchr1017235381Missense_MutationNAE407D0.18
UCECchr1017233818Missense_Mutationrs753092108D257N0.13
UCECchr1017229465Missense_MutationnovelF15V0.29
UCECchr1017236333Nonsense_MutationNAS438*0.28
UCECchr1017234738Missense_MutationnovelR310S0.35
UCECchr1017237256Silentrs368414175H462H0.43
UCECchr1017233846Missense_Mutationrs150878383T266M0.29
UCECchr10172373143'UTRnovel0.06
UCECchr10172373783'UTRrs1122799260.33
UCECchr1017233611Missense_Mutationrs752236825R217C0.47
UCECchr10172375303'UTRnovel0.43
UCECchr1017229814Missense_MutationnovelL131R0.52
UCECchr1017235220Missense_MutationNAE354K0.25
UCECchr1017229757Missense_MutationnovelD112G0.07
UCECchr1017235196Nonsense_MutationnovelE346*0.42
UCECchr1017234783Missense_MutationnovelS325P0.39
UCECchr1017235291SilentNAA377A0.17
UCECchr1017233664SilentnovelL234L0.25
UCECchr1017235194Missense_Mutationrs116370722R345H0.38
UCECchr1017235207Missense_MutationNAE349D0.39
UCECchr1017233605Missense_MutationNAL215V0.38
UCECchr10172373423'UTRnovel0.07
UCECchr1017229867Missense_MutationnovelL149F0.36
UCECchr1017233632Missense_MutationnovelV224L0.25
UCECchr1017233623Missense_MutationNAE221K0.2
UCECchr1017233817Silentrs377349430I256I0.18
UCECchr1017235298Missense_MutationnovelL380I0.16
UCECchr1017230669Frame_Shift_InsNAE198Rfs*380.36

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
ACCDEL0.12220.19593
BLCADEL0.11520.16614
PAADDEL0.13040.169
STADDEL0.10430.13903

Survival Analysis
CancerP-value Q-value
THYM0.043

Kaplan-Meier Survival Analysis

KIRC0.016

Kaplan-Meier Survival Analysis

STAD0.0012

Kaplan-Meier Survival Analysis

SARC0.019

Kaplan-Meier Survival Analysis

MESO0.00014

Kaplan-Meier Survival Analysis

ACC0.0037

Kaplan-Meier Survival Analysis

BRCA0.012

Kaplan-Meier Survival Analysis

KIRP0.023

Kaplan-Meier Survival Analysis

COAD0.011

Kaplan-Meier Survival Analysis

PCPG0.011

Kaplan-Meier Survival Analysis

BLCA0.014

Kaplan-Meier Survival Analysis

UCEC0.0001

Kaplan-Meier Survival Analysis

DLBC0.039

Kaplan-Meier Survival Analysis

UVM0.00016

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • Phenotypes
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000026025 (Gene tree)
Gene ID
7431
Gene Symbol
VIM
Alias
N
Full Name
vimentin
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
9,659 bases
Position
chr10:17,227,935-17,237,593
Accession
12692
RBP type
non-canonical RBP
Summary
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNANascentRICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
31059735Musashi-2 and related stem cell proteins in the mouse suprachiasmatic nucleus and their potential role in circadian rhythms.Int J Dev Neurosci2019 JunBeligala DHdoi: 10.1016/j.ijdevneu.2019.04.007
25890165Role of human heterogeneous nuclear ribonucleoprotein C1/C2 in dengue virus replication.Virol J2015 Feb 6Dechtawewat Tdoi: 10.1186/s12985-014-0219-7.
31234698Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits.Autophagy2019 Jun 24:1-19Jung Sdoi: 10.1080/15548627.2019.1630222
30677389Characterization of the novel spontaneously immortalized rat Muller cell line SIRMu-1.Exp Eye Res2019 AprKittipassorn Tdoi: 10.1016/j.exer.2019.01.013
6325477Differential effect of arginine modification with 1,2-cyclohexanedione on the capacity of vimentin and desmin to assemble into intermediate filaments and to bind to nucleic acids.J Cell Sci1984 JanTraub P-
9241253RNA-protein interactions within the 3 ' untranslated region of vimentin mRNA.Nucleic Acids Res1997 Aug 15Zehner ZE-
12466525The 3' untranslated region of human vimentin mRNA interacts with protein complexes containing eEF-1gamma and HAX-1.Nucleic Acids Res2002 Dec 1Al-Maghrebi M-
15699629Interaction in vitro of type III intermediate filament proteins with higher order structures of single-stranded DNA, particularly with G-quadruplex DNA.DNA Cell Biol2005 FebTolstonog GV-
18410440Application of transcript profiling in formalin-fixed paraffin-embedded diagnostic prostate cancer needle biopsies.BJU Int2008 AugRogerson Ldoi: 10.1111/j.1464-410X.2008.07627.x
27011170LARP6 Meets Collagen mRNA: Specific Regulation of Type I Collagen Expression.Int J Mol Sci2016 Mar 22Zhang Ydoi: 10.3390/ijms17030419.
30508278Characterizations of HSP90-Interacting Complex in Renal Cells Using Tandem Affinity Purification and Its Potential Role in Kidney Stone Formation.Proteomics2018 DecManissorn Jdoi: 10.1002/pmic.201800004.
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000485947VIM-2051139--- (aa)--
ENST00000478746VIM-204757-ENSP00000489830149 (aa)-A0A1B0GTT5
ENST00000497849VIM-208634-ENSP00000490509109 (aa)-A0A1B0GVG8
ENST00000487938VIM-2062272-ENSP00000435613431 (aa)-B0YJC4
ENST00000544301VIM-2092135-ENSP00000446007466 (aa)-P08670
ENST00000224237VIM-2011868XM_006717500ENSP00000224237466 (aa)XP_006717563P08670
ENST00000469543VIM-2032666-ENSP00000431702228 (aa)-B0YJC5
ENST00000421459VIM-202753--- (aa)--
ENST00000637053VIM-210508--- (aa)--
ENST00000495528VIM-207962--- (aa)--
Gene Model
Click here to download ENSG00000026025's gene model file
Pathways
Pathway IDPathway NameSource
hsa05169Epstein-Barr virus infectionKEGG
hsa05206MicroRNAs in cancerKEGG
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000026025Forced Expiratory Volume2.1850000E-005-
ENSG00000026025Vital Capacity4.9580000E-005-
ENSG00000026025Vital Capacity1.8760000E-005-
ENSG00000026025Platelet Function Tests5.4400000E-006-
ENSG00000026025Platelet Function Tests1.5267800E-005-
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000026025's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000026025VIM10097.425ENSMUSG00000026728Vim10097.425Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003725double-stranded RNA binding21266579.IDAFunction
GO:0005200structural constituent of cytoskeleton11889032.IDAFunction
GO:0005212structural constituent of eye lens-IEAFunction
GO:0005515protein binding10852826.11827972.15161933.15383276.15671067.15846844.16169070.16189514.16361107.16712842.16923132.17056548.18811945.18827015.19420356.20603131.20618440.20729920.20856200.21699783.21900206.22300583.22684479.23112296.24284321.25218743.25416956.26496610.27107012.27173435.27812135.30021884.IPIFunction
GO:0005737cytoplasm9150946.15846844.21914078.27919618.29496907.IDAComponent
GO:0005777peroxisome17881773.IDAComponent
GO:0005829cytosol21746880.IDAComponent
GO:0005829cytosol-TASComponent
GO:0005844polysome20603131.21746880.IDAComponent
GO:0005856cytoskeleton16769727.IDAComponent
GO:0005856cytoskeleton16130169.TASComponent
GO:0005882intermediate filament11889032.29496907.IDAComponent
GO:0005886plasma membrane-IDAComponent
GO:0005925focal adhesion21423176.HDAComponent
GO:0008022protein C-terminus binding-IPIFunction
GO:0010977negative regulation of neuron projection development-IEAProcess
GO:0014002astrocyte development-IEAProcess
GO:0016032viral process-IEAProcess
GO:0016363nuclear matrix-IEAComponent
GO:0019221cytokine-mediated signaling pathway-TASProcess
GO:0019904protein domain specific binding21746880.IPIFunction
GO:0030049muscle filament sliding-TASProcess
GO:0031252cell leading edge-IEAComponent
GO:0032967positive regulation of collagen biosynthetic process21746880.IMPProcess
GO:0042802identical protein binding15383276.16169070.17050693.21900206.22869704.IPIFunction
GO:0043005neuron projection-IEAComponent
GO:0043488regulation of mRNA stability21746880.IMPProcess
GO:0045109intermediate filament organization-IEAProcess
GO:0045335phagocytic vesicle-IEAComponent
GO:0045727positive regulation of translation21746880.IMPProcess
GO:0060020Bergmann glial cell differentiation-IEAProcess
GO:0060395SMAD protein signal transduction-IEAProcess
GO:0070062extracellular exosome20458337.21362503.HDAComponent
GO:0070307lens fiber cell development-IEAProcess
GO:0071222cellular response to lipopolysaccharide27812135.IMPProcess
GO:0071225cellular response to muramyl dipeptide27812135.IMPProcess
GO:0071346cellular response to interferon-gamma-IEAProcess
GO:0097110scaffold protein binding10852826.IPIFunction
GO:1990254keratin filament binding15846844.IPIFunction
GO:1990904ribonucleoprotein complex21746880.IDAComponent
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