EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
15215162	TRIO amplification and abundant mRNA expression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer.	Am J Pathol	2004 Jul	Zheng M	-
19008376	The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.	Am J Pathol	2008 Dec	Salhia B	doi: 10.2353/ajpath.2008.080043
29207149	Knockdown of Trio by CRISPR/Cas9 suppresses migration and invasion of cervical cancer cells.	Oncol Rep	2018 Feb	Hou C	doi: 10.3892/or.2017.6117

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr5	14387743	Silent	novel	L1259L	0.39
BLCA	chr5	14359454	Missense_Mutation	NA	E772Q	0.07
BLCA	chr5	14471432	Missense_Mutation	novel	E1960Q	0.62
BLCA	chr5	14381191	Missense_Mutation	NA	S1170C	0.37
BLCA	chr5	14387819	Missense_Mutation	NA	E1285Q	0.11
BLCA	chr5	14398960	Nonsense_Mutation	NA	R1502*	0.07
BLCA	chr5	14358204	Silent	rs750259424	Q691Q	0.33
BLCA	chr5	14336565	Silent	novel	L628L	0.5
BLCA	chr5	14482690	Missense_Mutation	novel	E2192Q	0.45
BLCA	chr5	14297123	Missense_Mutation	novel	E410Q	0.2
BLCA	chr5	14498630	Silent	novel	L2774L	0.1
BLCA	chr5	14482728	Missense_Mutation	novel	K2204N	0.28
BLCA	chr5	14492812	Splice_Region	novel	L2626L	0.07
BLCA	chr5	14487481	Missense_Mutation	rs776030839	E2285K	0.32
BLCA	chr5	14502638	Missense_Mutation	novel	E2798K	0.27
BLCA	chr5	14304516	Missense_Mutation	NA	S475L	0.05
BLCA	chr5	14496992	Missense_Mutation	NA	G2665E	0.17
BLCA	chr5	14398954	Missense_Mutation	NA	L1500V	0.2
BLCA	chr5	14498565	Missense_Mutation	novel	D2753Y	0.27
BLCA	chr5	14290937	Silent	novel	R254R	0.27
BLCA	chr5	14387626	Missense_Mutation	novel	N1253K	0.63
BLCA	chr5	14336545	Missense_Mutation	novel	T622A	0.31
BLCA	chr5	14358345	Splice_Region	novel	L738L	0.39
BLCA	chr5	14387487	Missense_Mutation	NA	C1207S	0.21
BLCA	chr5	14508017	Missense_Mutation	novel	I2963M	0.51
BLCA	chr5	14507136	Missense_Mutation	rs781136104	R2876H	0.21
BLCA	chr5	14406633	Silent	rs147339578	I1640I	0.15
BLCA	chr5	14304578	Missense_Mutation	novel	L496V	0.04
BLCA	chr5	14481588	Missense_Mutation	novel	M2145I	0.15
BLCA	chr5	14485159	Missense_Mutation	NA	I2250V	0.14
BLCA	chr5	14389322	Missense_Mutation	NA	E1328K	0.3
BLCA	chr5	14364721	Missense_Mutation	novel	E887K	0.07
BLCA	chr5	14398993	Missense_Mutation	novel	E1513Q	0.39
BLCA	chr5	14293122	Frame_Shift_Ins	novel	*C391Efs50**	0.11
BLCA	chr5	14358265	Missense_Mutation	rs199843575	R712C	0.37
BLCA	chr5	14363859	Frame_Shift_Del	novel	*L841Ffs2**	0.27
BLCA	chr5	14496988	Missense_Mutation	novel	E2664Q	0.42
BLCA	chr5	14492698	Missense_Mutation	rs368253813	M2588I	0.17
BLCA	chr5	14508191	Missense_Mutation	novel	Q3021H	0.29
BRCA	chr5	14462804	Missense_Mutation	novel	S1849F	0.1
BRCA	chr5	14368722	Silent	rs10064745	S963S	0.31
BRCA	chr5	14498145	Missense_Mutation	novel	V2702L	0.04
BRCA	chr5	14481610	Nonsense_Mutation	NA	G2153*	0.11
BRCA	chr5	14498627	Missense_Mutation	NA	S2773R	0.22
BRCA	chr5	14509148	3'UTR	novel		0.18
BRCA	chr5	14504483	Silent	rs760721624	R2834R	0.23
BRCA	chr5	14399053	Missense_Mutation	NA	Y1533H	0.31
BRCA	chr5	14507209	In_Frame_Del	novel	E2901del	0.07
BRCA	chr5	14316522	Missense_Mutation	novel	D504Y	0.08
BRCA	chr5	14476934	Missense_Mutation	novel	E2042K	0.13
BRCA	chr5	14363764	Silent	NA	E808E	0.25
BRCA	chr5	14479973	Missense_Mutation	novel	P2100A	0.11
BRCA	chr5	14507138	Missense_Mutation	rs748327260	L2877F	0.19
BRCA	chr5	14358312	Silent	novel	V727V	0.09
BRCA	chr5	14287051	Silent	NA	K176K	0.33
BRCA	chr5	14399067	Silent	NA	L1537L	0.17
BRCA	chr5	14304492	Missense_Mutation	novel	A467D	0.09
BRCA	chr5	14358253	Missense_Mutation	NA	D708H	0.38
BRCA	chr5	14290787	Silent	NA	G204G	0.23
BRCA	chr5	14398961	Missense_Mutation	NA	R1502Q	0.13
BRCA	chr5	14482626	Missense_Mutation	NA	F2170L	0.14
BRCA	chr5	14498102	Silent	rs371720824	F2687F	0.11
BRCA	chr5	14465681	Intron	NA		0.16
BRCA	chr5	14480008	Silent	NA	L2111L	0.28
BRCA	chr5	14472651	Missense_Mutation	NA	V1991A	0.21
BRCA	chr5	14358213	Silent	NA	L694L	0.4
BRCA	chr5	14358223	Missense_Mutation	NA	V698M	0.42
BRCA	chr5	14290818	Missense_Mutation	NA	E215K	0.24
BRCA	chr5	14507163	Missense_Mutation	NA	G2885E	0.24
CESC	chr5	14441240	Intron	novel		0.25
CESC	chr5	14359480	Missense_Mutation	NA	I780M	0.3
CESC	chr5	14485187	Missense_Mutation	rs750947029	R2259Q	0.22
CESC	chr5	14374288	Silent	rs145133665	S1092S	0.08
CESC	chr5	14378093	Missense_Mutation	novel	Q1138R	0.45
CESC	chr5	14488778	Intron	novel		0.53
CESC	chr5	14509412	3'UTR	novel		0.16
CESC	chr5	14291156	Missense_Mutation	novel	Q327H	0.25
CESC	chr5	14316725	Silent	novel	F571F	0.32
CESC	chr5	14462807	Missense_Mutation	NA	S1850L	0.34
CESC	chr5	14507182	Missense_Mutation	NA	K2891N	0.29
CESC	chr5	14508677	3'UTR	novel		0.26
CESC	chr5	14482625	Missense_Mutation	novel	F2170C	0.1
CESC	chr5	14476894	Missense_Mutation	rs371806945	D2028E	0.34
CESC	chr5	14290776	Missense_Mutation	NA	E201K	0.29
CESC	chr5	14336596	Missense_Mutation	novel	E639K	0.47
CESC	chr5	14389312	Silent	novel	S1324S	0.33
CESC	chr5	14405867	Missense_Mutation	novel	K1579R	0.09
CESC	chr5	14492714	Missense_Mutation	rs759385450	A2594T	0.24
CESC	chr5	14488816	Intron	novel		0.44
CESC	chr5	14358345	Splice_Region	novel	L738L	0.38
CESC	chr5	14461279	Frame_Shift_Ins	novel	*T1824Gfs66**	0.43
CESC	chr5	14368773	Silent	rs142713400	Y980Y	0.14
CESC	chr5	14405860	Missense_Mutation	novel	E1577Q	0.22
COAD	chr5	14316703	Missense_Mutation	novel	Q564R	0.17
COAD	chr5	14330791	Missense_Mutation	NA	I582N	0.48
COAD	chr5	14387792	Nonsense_Mutation	NA	R1276*	0.45
COAD	chr5	14336645	Missense_Mutation	rs753710560	R655Q	0.21
COAD	chr5	14287035	Missense_Mutation	NA	N171T	0.39
COAD	chr5	14336662	Missense_Mutation	NA	R661W	0.4
COAD	chr5	14476940	Missense_Mutation	NA	L2044I	0.31
COAD	chr5	14508206	Silent	rs200447498	F3026F	0.45
COAD	chr5	14358231	Silent	NA	A700A	0.27
COAD	chr5	14358222	Silent	rs778327240	D697D	0.52
COAD	chr5	14368837	Missense_Mutation	novel	K1002E	0.06
COAD	chr5	14399061	Missense_Mutation	novel	S1535R	0.14
COAD	chr5	14488020	Silent	novel	A2464A	0.43
COAD	chr5	14387518	Frame_Shift_Del	NA	*K1219Nfs43**	0.11
COAD	chr5	14487672	Frame_Shift_Del	rs746654944	*V2351Cfs62**	0.35
COAD	chr5	14286914	Missense_Mutation	NA	R131C	0.3
COAD	chr5	14465616	Missense_Mutation	NA	I1913M	0.32
COAD	chr5	14374312	Silent	NA	T1100T	0.09
COAD	chr5	14387497	Silent	NA	G1210G	0.37
COAD	chr5	14508233	Silent	rs369006273	P3035P	0.17
COAD	chr5	14286914	Missense_Mutation	NA	R131C	0.09
COAD	chr5	14358220	Missense_Mutation	NA	D697N	0.19
COAD	chr5	14297191	Silent	rs141998293	A432A	0.38
COAD	chr5	14508092	Silent	rs55898643	G2988G	0.24
COAD	chr5	14316672	Missense_Mutation	NA	I554V	0.34
COAD	chr5	14481586	Missense_Mutation	novel	M2145V	0.38
COAD	chr5	14487510	Silent	NA	G2294G	0.36
COAD	chr5	14394100	Silent	novel	Q1427Q	0.07
COAD	chr5	14508346	Missense_Mutation	NA	R3073H	0.37
COAD	chr5	14508003	Missense_Mutation	rs780863165	A2959T	0.16
COAD	chr5	14270832	Frame_Shift_Del	NA	*N57Tfs4**	0.32
COAD	chr5	14487672	Frame_Shift_Del	rs746654944	*V2351Cfs62**	0.29
COAD	chr5	14369468	Missense_Mutation	novel	D1054A	0.16
COAD	chr5	14487940	Missense_Mutation	novel	R2438C	0.17
COAD	chr5	14508678	3'UTR	novel		0.25
COAD	chr5	14316693	Missense_Mutation	rs761067835	R561W	0.14
COAD	chr5	14363820	Missense_Mutation	rs370634993	R827H	0.14
COAD	chr5	14488114	Nonsense_Mutation	NA	R2496*	0.35
COAD	chr5	14487672	Frame_Shift_Del	rs746654944	*V2351Cfs62**	0.3
COAD	chr5	14358222	Silent	rs778327240	D697D	0.47
COAD	chr5	14363853	Missense_Mutation	NA	M838T	0.42
COAD	chr5	14471330	Missense_Mutation	NA	R1926C	0.06
COAD	chr5	14508023	Silent	rs546106927	L2965L	0.39
COAD	chr5	14504524	Missense_Mutation	novel	Q2848R	0.21
COAD	chr5	14374299	Missense_Mutation	NA	P1096Q	0.13
COAD	chr5	14401012	Missense_Mutation	NA	F1555S	0.09
COAD	chr5	14485236	Missense_Mutation	novel	N2275K	0.16
COAD	chr5	14387518	Frame_Shift_Del	NA	*K1219Nfs43**	0.2
COAD	chr5	14270856	Missense_Mutation	novel	M63I	0.24
COAD	chr5	14280323	Splice_Region	NA	G78G	0.3
COAD	chr5	14479341	Silent	NA	T2078T	0.32
COAD	chr5	14389293	Missense_Mutation	novel	Y1318F	0.12
COAD	chr5	14461022	Missense_Mutation	NA	S1736L	0.24
COAD	chr5	14465543	Splice_Site	NA	X1890_splice	0.19
COAD	chr5	14508002	Silent	rs572269818	F2958F	0.35
COAD	chr5	14369389	Frame_Shift_Del	NA	*E1028Rfs29**	0.41
COAD	chr5	14369465	Missense_Mutation	rs754511053	T1053M	0.32
COAD	chr5	14488201	Missense_Mutation	NA	R2525C	0.27
DLBC	chr5	14397119	Missense_Mutation	rs373502206	R1463Q	0.09
DLBC	chr5	14359393	Missense_Mutation	novel	N751K	0.41
ESCA	chr5	14368861	Missense_Mutation	novel	V1010I	0.13
ESCA	chr5	14369505	Silent	novel	Q1066Q	0.09
ESCA	chr5	14390988	Missense_Mutation	novel	D1406N	0.1
ESCA	chr5	14358309	Silent	rs762757315	N726N	0.29
ESCA	chr5	14406634	Missense_Mutation	rs775980433	A1641T	0.42
ESCA	chr5	14419837	Silent	rs540921917	N1673N	0.63
ESCA	chr5	14489166	Intron	novel		0.74
GBM	chr5	14389293	Missense_Mutation	novel	Y1318S	0.06
GBM	chr5	14387843	Nonsense_Mutation	novel	K1293*	0.19
GBM	chr5	14364719	Missense_Mutation	novel	H886P	0.2
GBM	chr5	14374312	Silent	NA	T1100T	0.34
GBM	chr5	14502581	Missense_Mutation	rs745436046	P2779S	0.25
GBM	chr5	14462866	Missense_Mutation	NA	P1870A	0.55
GBM	chr5	14399078	Splice_Region	novel		0.07
GBM	chr5	14286874	Missense_Mutation	novel	E117D	0.12
GBM	chr5	14389337	Missense_Mutation	rs770762103	I1333V	0.19
GBM	chr5	14336645	Missense_Mutation	rs753710560	R655Q	0.19
GBM	chr5	14381156	Silent	rs199861793	G1158G	0.35
GBM	chr5	14394112	Missense_Mutation	novel	K1431N	0.14
GBM	chr5	14405891	Missense_Mutation	rs753950455	R1587H	0.21
GBM	chr5	14366938	Missense_Mutation	novel	Q945K	0.68
GBM	chr5	14405862	Silent	novel	E1577E	0.18
GBM	chr5	14498565	Missense_Mutation	novel	D2753Y	0.53
GBM	chr5	14358310	Missense_Mutation	rs748582661	V727M	0.26
GBM	chr5	14406603	Silent	rs780909267	D1630D	0.3
GBM	chr5	14389291	Splice_Region	novel	T1317T	0.04
GBM	chr5	14471345	Missense_Mutation	novel	L1931F	0.1
GBM	chr5	14508226	Missense_Mutation	novel	E3033G	0.08
GBM	chr5	14498560	Missense_Mutation	rs746758470	T2751M	0.47
GBM	chr5	14471323	Silent	novel	L1923L	0.08
GBM	chr5	14496943	Missense_Mutation	NA	G2649C	0.04
GBM	chr5	14492630	Nonsense_Mutation	novel	K2566*	0.06
GBM	chr5	14471445	Missense_Mutation	novel	S1964C	0.04
GBM	chr5	14363821	Silent	novel	R827R	0.08
GBM	chr5	14498632	Missense_Mutation	novel	R2775T	0.07
HNSC	chr5	14381223	Missense_Mutation	rs773995062	E1181Q	0.31
HNSC	chr5	14504559	Missense_Mutation	novel	E2860Q	0.03
HNSC	chr5	14291065	Nonsense_Mutation	novel	S297*	0.18
HNSC	chr5	14290723	Missense_Mutation	novel	M183T	0.13
HNSC	chr5	14369450	Missense_Mutation	novel	G1048D	0.22
HNSC	chr5	14487504	Silent	novel	G2292G	0.29
HNSC	chr5	14508346	Missense_Mutation	NA	R3073H	0.22
HNSC	chr5	14405939	Missense_Mutation	novel	E1603G	0.29
HNSC	chr5	14419882	Silent	novel	R1688R	0.53
HNSC	chr5	14368854	Silent	rs756381004	L1007L	0.12
HNSC	chr5	14291201	Silent	novel	L342L	0.24
HNSC	chr5	14399183	Intron	novel		0.5
HNSC	chr5	14304513	Missense_Mutation	rs766016794	P474L	0.21
HNSC	chr5	14479969	Missense_Mutation	novel	I2098M	0.53
HNSC	chr5	14476963	Missense_Mutation	novel	H2051Q	0.13
HNSC	chr5	14419929	Missense_Mutation	novel	S1704C	0.56
HNSC	chr5	14504589	Missense_Mutation	novel	E2870Q	0.05
HNSC	chr5	14492623	Silent	rs764670811	T2563T	0.11
HNSC	chr5	14492639	Missense_Mutation	novel	E2569K	0.1
HNSC	chr5	14488137	Silent	novel	P2503P	0.21
HNSC	chr5	14368871	Missense_Mutation	novel	S1013F	0.37
KICH	chr5	14508572	3'UTR	novel		0.53
KIRC	chr5	14363907	Missense_Mutation	NA	V856G	0.05
KIRC	chr5	14497010	Missense_Mutation	NA	S2671Y	0.23
KIRC	chr5	14485115	Missense_Mutation	NA	K2235I	0.29
KIRC	chr5	14462916	Frame_Shift_Ins	novel	*D1887Lfs10**	0.26
KIRP	chr5	14497006	Missense_Mutation	NA	V2670L	0.25
KIRP	chr5	14401003	Missense_Mutation	novel	P1552H	0.45
KIRP	chr5	14387563	Frame_Shift_Del	novel	*L1233Cfs29**	0.39
KIRP	chr5	14496907	Missense_Mutation	NA	R2637S	0.44
KIRP	chr5	14471451	Missense_Mutation	NA	S1966F	0.72
LAML	chr5	14286915	Missense_Mutation	NA	R131H	0.42
LGG	chr5	14406644	Missense_Mutation	rs55687522	T1644M	0.31
LGG	chr5	14399060	Missense_Mutation	novel	S1535N	0.08
LGG	chr5	14462811	Silent	novel	G1851G	0.07
LGG	chr5	14471382	Missense_Mutation	rs745976496	N1943S	0.24
LIHC	chr5	14270831	Missense_Mutation	NA	R55Q	0.61
LIHC	chr5	14280362	Silent	novel	P91P	0.08
LIHC	chr5	14368871	Missense_Mutation	novel	S1013C	0.38
LIHC	chr5	14487517	Missense_Mutation	NA	G2297S	0.13
LIHC	chr5	14394102	Missense_Mutation	NA	R1428Q	0.39
LIHC	chr5	14304528	Missense_Mutation	novel	D479G	0.17
LUAD	chr5	14507217	Missense_Mutation	novel	V2903D	0.11
LUAD	chr5	14498125	Missense_Mutation	novel	T2695K	0.26
LUAD	chr5	14481275	Silent	novel	S2126S	0.17
LUAD	chr5	14280410	Silent	rs764200107	L107L	0.07
LUAD	chr5	14291228	Missense_Mutation	NA	K351N	0.25
LUAD	chr5	14419850	Nonsense_Mutation	rs749963113	R1678*	0.24
LUAD	chr5	14291125	Missense_Mutation	novel	R317L	0.26
LUAD	chr5	14507988	Missense_Mutation	novel	G2954W	0.09
LUAD	chr5	14482596	Silent	novel	A2160A	0.37
LUAD	chr5	14369380	Missense_Mutation	NA	S1025C	0.08
LUAD	chr5	14291204	Silent	NA	R343R	0.27
LUAD	chr5	14502590	Missense_Mutation	novel	D2782N	0.34
LUAD	chr5	14419926	Missense_Mutation	novel	R1703L	0.06
LUAD	chr5	14488913	Intron	novel		0.44
LUAD	chr5	14485147	Missense_Mutation	novel	V2246L	0.56
LUAD	chr5	14507197	Silent	NA	L2896L	0.31
LUAD	chr5	14280361	Missense_Mutation	rs767063550	P91L	0.41
LUAD	chr5	14474089	Missense_Mutation	NA	W2025C	0.11
LUAD	chr5	14287055	Missense_Mutation	NA	E178K	0.09
LUAD	chr5	14398903	Missense_Mutation	novel	Q1483E	0.05
LUAD	chr5	14462841	Missense_Mutation	novel	E1861D	0.07
LUAD	chr5	14472638	Missense_Mutation	novel	D1987Y	0.62
LUAD	chr5	14330900	Missense_Mutation	novel	Q618H	0.2
LUAD	chr5	14330901	Splice_Site	novel	X618_splice	0.19
LUAD	chr5	14280425	Silent	novel	A112A	0.04
LUAD	chr5	14508523	3'UTR	novel		0.09
LUAD	chr5	14390274	Missense_Mutation	novel	D1368Y	0.43
LUAD	chr5	14330834	Silent	novel	V596V	0.21
LUAD	chr5	14330835	Missense_Mutation	novel	G597W	0.2
LUAD	chr5	14369418	Silent	novel	E1037E	0.06
LUAD	chr5	14488913	Intron	novel		0.44
LUAD	chr5	14358251	Missense_Mutation	NA	Q707L	0.09
LUAD	chr5	14479294	Nonsense_Mutation	NA	Q2063*	0.06
LUAD	chr5	14474038	Missense_Mutation	novel	M2008I	0.13
LUAD	chr5	14508244	Missense_Mutation	novel	P3039L	0.31
LUAD	chr5	14462809	Missense_Mutation	NA	G1851W	0.5
LUAD	chr5	14358210	Missense_Mutation	NA	E693D	0.17
LUAD	chr5	14406612	Silent	novel	S1633S	0.2
LUAD	chr5	14482581	Splice_Site	novel	X2156_splice	0.29
LUAD	chr5	14507963	Silent	novel	T2945T	0.12
LUAD	chr5	14291140	Missense_Mutation	novel	R322L	0.17
LUAD	chr5	14291141	Silent	novel	R322R	0.18
LUAD	chr5	14419785	Missense_Mutation	novel	G1656V	0.18
LUAD	chr5	14359398	Missense_Mutation	NA	S753F	0.49
LUAD	chr5	14286890	Missense_Mutation	novel	G123C	0.11
LUAD	chr5	14481266	Silent	NA	L2123L	0.07
LUAD	chr5	14378011	Splice_Site	NA	X1111_splice	0.3
LUSC	chr5	14291008	Missense_Mutation	novel	E278G	0.19
LUSC	chr5	14330897	Silent	NA	A617A	0.3
LUSC	chr5	14290995	Missense_Mutation	novel	D274Y	0.18
LUSC	chr5	14363878	Silent	novel	I846I	0.09
LUSC	chr5	14270887	Missense_Mutation	novel	A74T	0.13
LUSC	chr5	14508317	Silent	novel	T3063T	0.43
LUSC	chr5	14291121	Missense_Mutation	novel	D316H	0.08
LUSC	chr5	14387607	Missense_Mutation	novel	G1247E	0.38
LUSC	chr5	14507193	Missense_Mutation	NA	H2895L	0.39
LUSC	chr5	14502633	Missense_Mutation	novel	Y2796C	0.79
LUSC	chr5	14471340	Missense_Mutation	novel	S1929L	0.34
LUSC	chr5	14476963	Splice_Region	rs746238974	H2051H	0.23
LUSC	chr5	14336611	Missense_Mutation	NA	E644Q	0.09
LUSC	chr5	14304549	Missense_Mutation	novel	H486R	0.1
LUSC	chr5	14399093	Intron	rs779390179		0.31
LUSC	chr5	14297174	Missense_Mutation	rs747731735	E427Q	0.24
LUSC	chr5	14330836	Missense_Mutation	novel	G597A	0.18
LUSC	chr5	14368812	Silent	rs570447608	A993A	0.25
LUSC	chr5	14485161	Missense_Mutation	NA	I2250M	0.44
LUSC	chr5	14286874	Silent	NA	E117E	0.19
LUSC	chr5	14498628	Silent	NA	L2774L	0.13
LUSC	chr5	14488091	Missense_Mutation	rs748080841	S2488C	0.11
LUSC	chr5	14462763	Silent	novel	R1835R	0.27
LUSC	chr5	14465568	Silent	NA	R1897R	0.06
LUSC	chr5	14390231	Splice_Region	novel	N1353N	0.47
LUSC	chr5	14394048	Missense_Mutation	novel	Q1410L	0.15
LUSC	chr5	14387509	Silent	novel	A1214A	0.04
LUSC	chr5	14471331	Missense_Mutation	rs375877998	R1926H	0.06
LUSC	chr5	14330850	Missense_Mutation	NA	R602G	0.15
LUSC	chr5	14406667	Missense_Mutation	novel	D1652Y	0.1
LUSC	chr5	14364761	Missense_Mutation	novel	R900L	0.28
LUSC	chr5	14291011	Missense_Mutation	novel	G279V	0.45
LUSC	chr5	14374245	Missense_Mutation	NA	R1078Q	0.25
LUSC	chr5	14508305	Silent	NA	G3059G	0.19
LUSC	chr5	14405909	Missense_Mutation	novel	R1593Q	0.29
LUSC	chr5	14465555	Missense_Mutation	novel	R1893L	0.32
LUSC	chr5	14488905	Intron	novel		0.5
MESO	chr5	14290856	Silent	novel	A227A	0.17
MESO	chr5	14507133	Missense_Mutation	novel	G2875A	0.13
OV	chr5	14485074	Silent	novel	S2221S	0.24
OV	chr5	14369372	Splice_Site	NA	X1023_splice	0.45
OV	chr5	14369505	Missense_Mutation	NA	Q1066H	0.2
OV	chr5	14358247	Missense_Mutation	NA	V706L	0.18
OV	chr5	14406639	Silent	NA	S1642S	0.47
OV	chr5	14399109	Intron	novel		0.09
OV	chr5	14399111	Intron	novel		0.07
OV	chr5	14297095	Silent	NA	R400R	0.19
OV	chr5	14406636	Silent	novel	A1641A	0.22
OV	chr5	14465713	Intron	novel		0.04
OV	chr5	14465714	Intron	novel		0.04
OV	chr5	14419831	Missense_Mutation	NA	N1671K	0.12
OV	chr5	14489052	Intron	novel		0.42
OV	chr5	14462783	Missense_Mutation	novel	G1842D	0.15
OV	chr5	14498245	Splice_Site	novel	X2736_splice	0.24
OV	chr5	14363882	Missense_Mutation	novel	Q848K	0.06
OV	chr5	14507176	Missense_Mutation	novel	E2889D	0.35
OV	chr5	14364659	Missense_Mutation	novel	L866R	0.12
OV	chr5	14489086	Intron	novel		0.18
PAAD	chr5	14369382	Silent	rs747758995	S1025S	0.15
PAAD	chr5	14387792	Nonsense_Mutation	NA	R1276*	0.2
PAAD	chr5	14406667	Missense_Mutation	rs765405800	D1652N	0.23
PAAD	chr5	14482698	Silent	rs139448086	I2194I	0.16
PAAD	chr5	14485186	Missense_Mutation	novel	R2259W	0.16
PAAD	chr5	14485239	Missense_Mutation	novel	F2276L	0.2
PCPG	chr5	14390952	Missense_Mutation	novel	T1394S	0.22
PCPG	chr5	14286966	Missense_Mutation	novel	S148C	0.32
PRAD	chr5	14359514	Missense_Mutation	novel	E792K	0.16
PRAD	chr5	14504540	Silent	rs754497690	V2853V	0.18
PRAD	chr5	14366881	Missense_Mutation	NA	G926R	0.2
PRAD	chr5	14504394	Missense_Mutation	NA	G2805S	0.07
PRAD	chr5	14363750	Missense_Mutation	NA	S804A	0.06
PRAD	chr5	14507970	Missense_Mutation	NA	Y2948H	0.13
PRAD	chr5	14482698	Silent	rs139448086	I2194I	0.4
PRAD	chr5	14492716	Silent	rs762432411	A2594A	0.48
READ	chr5	14363788	Silent	rs758409767	F816F	0.26
READ	chr5	14291015	Silent	NA	Q280Q	0.34
READ	chr5	14336662	Missense_Mutation	NA	R661W	0.33
READ	chr5	14508437	3'UTR	rs761742565		0.46
READ	chr5	14462838	Silent	rs146544278	G1860G	0.77
READ	chr5	14419819	Silent	NA	F1667F	0.35
READ	chr5	14290946	Silent	novel	I257I	0.63
READ	chr5	14508002	Silent	rs572269818	F2958F	0.4
SARC	chr5	14481608	Missense_Mutation	novel	Q2152L	0.22
SARC	chr5	14368723	Missense_Mutation	rs139892017	A964T	0.3
SARC	chr5	14359441	Silent	novel	A767A	0.51
SARC	chr5	14507207	Silent	novel	L2900L	0.33
SKCM	chr5	14488182	Silent	NA	A2518A	0.64
SKCM	chr5	14405930	Missense_Mutation	novel	A1600V	0.26
SKCM	chr5	14488982	Intron	rs779267083		0.23
SKCM	chr5	14462810	Missense_Mutation	NA	G1851E	0.52
SKCM	chr5	14399105	Intron	novel		0.21
SKCM	chr5	14462837	Missense_Mutation	NA	G1860D	0.23
SKCM	chr5	14476891	Splice_Region	novel		0.42
SKCM	chr5	14366901	Silent	rs141984882	A932A	0.15
SKCM	chr5	14368849	Missense_Mutation	NA	R1006C	0.27
SKCM	chr5	14465587	Missense_Mutation	NA	P1904S	0.1
SKCM	chr5	14492596	Silent	NA	S2554S	0.28
SKCM	chr5	14508366	Nonsense_Mutation	NA	R3080*	0.24
SKCM	chr5	14482660	Missense_Mutation	rs373321656	R2182C	0.16
SKCM	chr5	14488098	Silent	rs748883903	P2490P	0.28
SKCM	chr5	14419849	Silent	rs374579202	I1677I	0.51
SKCM	chr5	14488173	Silent	NA	R2515R	0.25
SKCM	chr5	14280404	Silent	novel	R105R	0.29
SKCM	chr5	14492712	Missense_Mutation	novel	R2593P	0.19
SKCM	chr5	14280415	Missense_Mutation	NA	S109F	0.29
SKCM	chr5	14487473	Missense_Mutation	rs746676823	S2282L	0.56
SKCM	chr5	14394102	Missense_Mutation	NA	R1428Q	0.2
SKCM	chr5	14482745	Missense_Mutation	rs750016484	P2210L	0.09
SKCM	chr5	14336685	Silent	NA	I668I	0.12
SKCM	chr5	14497857	Missense_Mutation	NA	P2677L	0.06
SKCM	chr5	14405848	Missense_Mutation	NA	A1573T	0.44
SKCM	chr5	14363882	Nonsense_Mutation	novel	Q848*	0.21
SKCM	chr5	14369373	Splice_Site	NA	X1023_splice	0.21
SKCM	chr5	14363755	Nonsense_Mutation	NA	W805*	0.24
SKCM	chr5	14507948	Silent	NA	A2940A	0.13
SKCM	chr5	14507219	Missense_Mutation	rs748154890	R2904W	0.4
SKCM	chr5	14280406	Missense_Mutation	NA	R106K	0.2
SKCM	chr5	14369461	Missense_Mutation	NA	E1052K	0.1
SKCM	chr5	14387564	Silent	NA	L1233L	0.09
SKCM	chr5	14419944	Missense_Mutation	novel	G1709D	0.51
SKCM	chr5	14291084	Silent	novel	D303D	0.49
SKCM	chr5	14290992	Missense_Mutation	rs772378892	E273K	0.43
SKCM	chr5	14287055	Nonsense_Mutation	novel	E178*	0.35
SKCM	chr5	14304534	Missense_Mutation	NA	E481G	0.25
SKCM	chr5	14508023	Silent	rs546106927	L2965L	0.95
SKCM	chr5	14471426	Missense_Mutation	NA	E1958K	0.44
SKCM	chr5	14508464	3'UTR	novel		0.28
SKCM	chr5	14488983	Intron	novel		0.36
SKCM	chr5	14387792	Silent	NA	R1276R	0.49
SKCM	chr5	14420015	Missense_Mutation	rs368342075	H1733Y	0.28
SKCM	chr5	14498588	Silent	rs776118053	I2760I	0.44
SKCM	chr5	14304553	Silent	NA	H487H	0.16
SKCM	chr5	14474011	Missense_Mutation	NA	M1999I	0.07
SKCM	chr5	14482590	Silent	rs754779359	I2158I	0.32
SKCM	chr5	14476931	Missense_Mutation	novel	P2041S	0.49
SKCM	chr5	14492695	Silent	rs776305258	N2587N	0.33
SKCM	chr5	14270893	Missense_Mutation	NA	L76F	0.36
SKCM	chr5	14290942	Missense_Mutation	novel	M256K	0.3
SKCM	chr5	14462902	Nonsense_Mutation	novel	Q1882*	0.6
SKCM	chr5	14364697	Nonsense_Mutation	NA	Q879*	0.37
SKCM	chr5	14465662	Intron	novel		0.53
STAD	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.38
STAD	chr5	14492717	Missense_Mutation	rs369051747	A2595T	0.22
STAD	chr5	14498145	Missense_Mutation	rs200412299	V2702I	0.42
STAD	chr5	14291100	Missense_Mutation	NA	P309S	0.45
STAD	chr5	14364786	Silent	NA	Q908Q	0.43
STAD	chr5	14487672	Frame_Shift_Del	rs746654944	*V2351Cfs62**	0.26
STAD	chr5	14405943	Silent	NA	P1604P	0.57
STAD	chr5	14368774	Missense_Mutation	rs774072211	D981N	0.05
STAD	chr5	14462836	Missense_Mutation	NA	G1860C	0.33
STAD	chr5	14419850	Nonsense_Mutation	rs749963113	R1678*	0.25
STAD	chr5	14363746	Silent	rs141315662	L802L	0.18
STAD	chr5	14378045	Missense_Mutation	NA	R1122M	0.21
STAD	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.52
STAD	chr5	14487672	Frame_Shift_Del	rs746654944	*V2351Cfs62**	0.47
STAD	chr5	14291056	Missense_Mutation	NA	K294I	0.3
STAD	chr5	14297233	Missense_Mutation	NA	M446I	0.38
STAD	chr5	14488201	Missense_Mutation	NA	R2525C	0.41
STAD	chr5	14462772	Silent	rs764203841	G1838G	0.26
STAD	chr5	14280366	Missense_Mutation	rs767723793	R93C	0.21
STAD	chr5	14366880	Silent	rs370683728	N925N	0.46
STAD	chr5	14462820	Silent	novel	S1854S	0.1
STAD	chr5	14471385	Missense_Mutation	novel	P1944H	0.12
STAD	chr5	14485195	Missense_Mutation	novel	W2262R	0.35
STAD	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.42
STAD	chr5	14482585	Frame_Shift_Del	NA	*I2158Sfs63**	0.32
STAD	chr5	14280416	Silent	novel	S109S	0.18
STAD	chr5	14381199	Nonsense_Mutation	novel	Q1173*	0.16
STAD	chr5	14488047	Frame_Shift_Del	rs774597492	*S2476Afs51**	0.28
STAD	chr5	14363784	Missense_Mutation	NA	D815G	0.16
STAD	chr5	14405912	Missense_Mutation	novel	T1594M	0.26
STAD	chr5	14462868	Silent	rs138509776	P1870P	0.26
STAD	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.42
STAD	chr5	14507927	Missense_Mutation	novel	K2933N	0.38
STAD	chr5	14387749	Silent	NA	L1261L	0.37
STAD	chr5	14485136	Missense_Mutation	rs55916212	T2242M	0.25
STAD	chr5	14359436	Missense_Mutation	novel	E766K	0.1
STAD	chr5	14507135	Missense_Mutation	rs755026998	R2876C	0.34
STAD	chr5	14358317	Missense_Mutation	novel	K729T	0.11
STAD	chr5	14291124	Missense_Mutation	rs368654118	R317W	0.16
STAD	chr5	14387518	Frame_Shift_Del	NA	*K1219Nfs43**	0.48
STAD	chr5	14461290	Silent	novel	P1825P	0.33
STAD	chr5	14488046	Frame_Shift_Ins	novel	*S2476Pfs52**	0.36
STAD	chr5	14504483	Silent	NA	R2834R	0.33
STAD	chr5	14461281	Silent	NA	A1822A	0.3
STAD	chr5	14498521	Missense_Mutation	NA	D2738G	0.27
STAD	chr5	14508346	Missense_Mutation	NA	R3073H	0.33
STAD	chr5	14359447	Silent	rs200525310	S769S	0.08
STAD	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.45
STAD	chr5	14462857	Missense_Mutation	rs774835487	V1867M	0.4
STAD	chr5	14290915	Missense_Mutation	NA	P247L	0.36
STAD	chr5	14462844	Frame_Shift_Del	novel	*A1864Pfs32**	0.24
STAD	chr5	14387560	Missense_Mutation	NA	F1231L	0.23
STAD	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.27
STAD	chr5	14369445	Missense_Mutation	NA	K1046N	0.11
STAD	chr5	14488176	Silent	novel	H2516H	0.36
STAD	chr5	14487672	Frame_Shift_Del	rs746654944	*V2351Cfs62**	0.38
STAD	chr5	14481572	Missense_Mutation	NA	R2140M	0.18
STAD	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.44
STAD	chr5	14487672	Frame_Shift_Del	rs746654944	*V2351Cfs62**	0.27
STAD	chr5	14504540	Silent	rs754497690	V2853V	0.1
STAD	chr5	14504540	Silent	rs754497690	V2853V	0.39
STAD	chr5	14485130	Missense_Mutation	NA	S2240L	0.29
STAD	chr5	14389316	Missense_Mutation	NA	V1326M	0.41
STAD	chr5	14498599	Missense_Mutation	NA	D2764A	0.18
STAD	chr5	14366914	Missense_Mutation	rs751285174	A937T	0.21
STAD	chr5	14400982	Missense_Mutation	NA	T1545I	0.2
STAD	chr5	14316645	Missense_Mutation	novel	L545M	0.06
THCA	chr5	14492624	Missense_Mutation	NA	A2564T	0.3
THCA	chr5	14293067	Missense_Mutation	NA	I370T	0.3
THYM	chr5	14389328	Missense_Mutation	novel	P1330T	0.3
UCEC	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.41
UCEC	chr5	14485128	Silent	novel	T2239T	0.08
UCEC	chr5	14498608	Missense_Mutation	rs146227809	S2767L	0.32
UCEC	chr5	14401052	Missense_Mutation	NA	K1568N	0.37
UCEC	chr5	14482698	Silent	rs139448086	I2194I	0.28
UCEC	chr5	14508437	3'UTR	rs761742565		0.27
UCEC	chr5	14359523	Missense_Mutation	NA	A795T	0.26
UCEC	chr5	14389291	Splice_Region	rs752164149	T1317T	0.29
UCEC	chr5	14398960	Nonsense_Mutation	NA	R1502*	0.35
UCEC	chr5	14419910	Missense_Mutation	novel	V1698L	0.4
UCEC	chr5	14286915	Missense_Mutation	NA	R131H	0.34
UCEC	chr5	14336658	Silent	rs552869777	F659F	0.33
UCEC	chr5	14368876	Missense_Mutation	rs745774257	A1015T	0.24
UCEC	chr5	14398950	Missense_Mutation	novel	K1498N	0.14
UCEC	chr5	14462851	Missense_Mutation	novel	D1865N	0.33
UCEC	chr5	14497010	Missense_Mutation	NA	S2671Y	0.21
UCEC	chr5	14504481	Missense_Mutation	rs56400458	R2834C	0.23
UCEC	chr5	14508808	3'UTR	novel		0.58
UCEC	chr5	14290809	Nonsense_Mutation	NA	E212*	0.42
UCEC	chr5	14290992	Missense_Mutation	rs772378892	E273K	0.19
UCEC	chr5	14389364	Nonsense_Mutation	NA	G1342*	0.29
UCEC	chr5	14405881	Missense_Mutation	NA	K1584E	0.44
UCEC	chr5	14465605	Missense_Mutation	rs773375329	V1910I	0.1
UCEC	chr5	14471388	Missense_Mutation	rs771840207	S1945L	0.33
UCEC	chr5	14508532	3'UTR	novel		0.4
UCEC	chr5	14504408	Silent	rs779722932	V2809V	0.38
UCEC	chr5	14508584	3'UTR	novel		0.56
UCEC	chr5	14509156	3'UTR	novel		0.13
UCEC	chr5	14496970	Missense_Mutation	rs552382011	G2658S	0.42
UCEC	chr5	14336666	Missense_Mutation	NA	R662H	0.21
UCEC	chr5	14287017	Nonsense_Mutation	novel	W165*	0.41
UCEC	chr5	14316710	Silent	rs747007284	L566L	0.5
UCEC	chr5	14465682	Intron	novel		0.41
UCEC	chr5	14465604	Silent	rs200594729	L1909L	0.21
UCEC	chr5	14509281	3'UTR	novel		0.4
UCEC	chr5	14286872	Missense_Mutation	rs769526836	E117K	0.13
UCEC	chr5	14397148	Missense_Mutation	novel	L1473M	0.5
UCEC	chr5	14398897	Missense_Mutation	novel	E1481K	0.33
UCEC	chr5	14280367	Missense_Mutation	rs376866089	R93H	0.48
UCEC	chr5	14485236	Frame_Shift_Del	NA	L2277*	0.44
UCEC	chr5	14497010	Missense_Mutation	NA	S2671Y	0.38
UCEC	chr5	14293121	Missense_Mutation	NA	A388G	0.44
UCEC	chr5	14508098	Silent	novel	S2990S	0.08
UCEC	chr5	14508342	Missense_Mutation	novel	R3072W	0.12
UCEC	chr5	14364691	Missense_Mutation	NA	R877W	0.2
UCEC	chr5	14387606	Missense_Mutation	NA	G1247R	0.24
UCEC	chr5	14397053	Missense_Mutation	rs763926725	T1441M	0.23
UCEC	chr5	14405942	Missense_Mutation	NA	P1604L	0.29
UCEC	chr5	14508002	Silent	rs572269818	F2958F	0.22
UCEC	chr5	14406644	Missense_Mutation	rs55687522	T1644M	0.55
UCEC	chr5	14368737	Silent	novel	Q968Q	0.29
UCEC	chr5	14482590	Silent	rs754779359	I2158I	0.3
UCEC	chr5	14297196	Missense_Mutation	NA	A434V	0.25
UCEC	chr5	14316611	Silent	novel	A533A	0.29
UCEC	chr5	14336662	Missense_Mutation	NA	R661W	0.1
UCEC	chr5	14359505	Missense_Mutation	novel	R789C	0.17
UCEC	chr5	14485130	Missense_Mutation	NA	S2240L	0.05
UCEC	chr5	14330851	Missense_Mutation	novel	R602Q	0.38
UCEC	chr5	14508092	Silent	rs55898643	G2988G	0.42
UCEC	chr5	14291081	Silent	rs764374315	A302A	0.34
UCEC	chr5	14479961	Missense_Mutation	novel	L2096M	0.17
UCEC	chr5	14496966	Silent	novel	E2656E	0.2
UCEC	chr5	14359404	Missense_Mutation	novel	N755S	0.46
UCEC	chr5	14368789	Missense_Mutation	novel	R986W	0.11
UCEC	chr5	14297095	Silent	rs746674667	R400R	0.49
UCEC	chr5	14398976	Missense_Mutation	NA	R1507Q	0.22
UCEC	chr5	14397109	Missense_Mutation	novel	V1460M	0.36
UCEC	chr5	14336564	Missense_Mutation	novel	L628P	0.06
UCEC	chr5	14297103	Missense_Mutation	novel	S403L	0.44
UCEC	chr5	14508206	Silent	rs200447498	F3026F	0.19
UCEC	chr5	14290809	Nonsense_Mutation	NA	E212*	0.35
UCEC	chr5	14441136	Intron	novel		0.09
UCEC	chr5	14394101	Missense_Mutation	novel	R1428G	0.06
UCEC	chr5	14297159	Missense_Mutation	novel	I422V	0.34
UCEC	chr5	14304509	Missense_Mutation	novel	L473I	0.28
UCEC	chr5	14359417	Silent	novel	T759T	0.23
UCEC	chr5	14465788	Intron	novel		0.26
UCEC	chr5	14508808	3'UTR	novel		0.18
UCEC	chr5	14471397	Frame_Shift_Del	novel	*L1949Ffs19**	0.39
UCEC	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.29
UCEC	chr5	14504541	Missense_Mutation	rs778314493	G2854S	0.11
UCEC	chr5	14359416	Missense_Mutation	rs201514384	T759M	0.21
UCEC	chr5	14394052	Silent	novel	R1411R	0.35
UCEC	chr5	14399000	Missense_Mutation	novel	S1515Y	0.37
UCEC	chr5	14462853	Silent	rs539850349	D1865D	0.45
UCEC	chr5	14498590	Missense_Mutation	novel	A2761V	0.41
UCEC	chr5	14508077	Silent	rs199903389	Y2983Y	0.33
UCEC	chr5	14508253	Missense_Mutation	rs759482240	A3042V	0.53
UCEC	chr5	14290749	Missense_Mutation	NA	V192I	0.36
UCEC	chr5	14363788	Silent	rs758409767	F816F	0.36
UCEC	chr5	14507949	Missense_Mutation	rs767953889	V2941F	0.17
UCEC	chr5	14504514	Nonsense_Mutation	NA	Q2845*	0.42
UCEC	chr5	14508023	Silent	rs546106927	L2965L	0.48
UCEC	chr5	14290972	Missense_Mutation	novel	K266M	0.33
UCEC	chr5	14358266	Missense_Mutation	rs370241914	R712H	0.42
UCEC	chr5	14364749	Missense_Mutation	rs756805966	A896V	0.44
UCEC	chr5	14482710	Silent	rs756634289	S2198S	0.31
UCEC	chr5	14498145	Missense_Mutation	rs200412299	V2702I	0.39
UCEC	chr5	14509199	3'UTR	novel		0.44
UCEC	chr5	14465552	Missense_Mutation	novel	S1892Y	0.55
UCEC	chr5	14476955	Missense_Mutation	novel	V2049F	0.13
UCEC	chr5	14485235	Missense_Mutation	novel	N2275T	0.24
UCEC	chr5	14369433	Silent	rs754148709	G1042G	0.46
UCEC	chr5	14498125	Missense_Mutation	NA	T2695M	0.09
UCEC	chr5	14508007	Missense_Mutation	NA	A2960V	0.37
UCEC	chr5	14387518	Frame_Shift_Del	NA	*K1219Nfs43**	0.36
UCEC	chr5	14293076	Missense_Mutation	novel	S373N	0.37
UCEC	chr5	14291080	Missense_Mutation	rs761019734	A302V	0.17
UCEC	chr5	14482675	Missense_Mutation	NA	R2187C	0.13
UCEC	chr5	14368797	Silent	rs144236504	C988C	0.07
UCEC	chr5	14462844	Frame_Shift_Del	novel	*A1864Pfs32**	0.48
UCEC	chr5	14405895	Missense_Mutation	novel	E1588D	0.53
UCEC	chr5	14471388	Missense_Mutation	rs771840207	S1945L	0.38
UCEC	chr5	14497848	Missense_Mutation	novel	L2674R	0.4
UCEC	chr5	14508017	Silent	novel	I2963I	0.24
UCEC	chr5	14291228	Missense_Mutation	NA	K351N	0.33
UCEC	chr5	14364716	Missense_Mutation	novel	L885P	0.32
UCEC	chr5	14482771	Missense_Mutation	novel	K2219E	0.29
UCEC	chr5	14488893	Intron	novel		0.38
UCEC	chr5	14498212	Missense_Mutation	novel	N2724S	0.34
UCEC	chr5	14508028	Missense_Mutation	novel	N2967S	0.12
UCEC	chr5	14366901	Silent	rs141984882	A932A	0.04
UCEC	chr5	14462853	Silent	rs539850349	D1865D	0.13
UCEC	chr5	14290849	Missense_Mutation	novel	S225N	0.21
UCEC	chr5	14291060	Missense_Mutation	novel	K295N	0.14
UCEC	chr5	14399069	Missense_Mutation	novel	F1538C	0.24
UCEC	chr5	14465581	Missense_Mutation	novel	E1902K	0.19
UCEC	chr5	14316566	Silent	rs767860634	P518P	0.39
UCEC	chr5	14419850	Nonsense_Mutation	rs749963113	R1678*	0.35
UCEC	chr5	14509228	3'UTR	novel		0.38
UCEC	chr5	14465604	Silent	rs200594729	L1909L	0.34
UCEC	chr5	14394130	Splice_Region	novel	K1437K	0.4
UCEC	chr5	14485130	Missense_Mutation	NA	S2240L	0.4
UCEC	chr5	14488888	Intron	novel		0.4
UCEC	chr5	14492665	Silent	rs146231483	V2577V	0.3
UCEC	chr5	14508002	Silent	rs572269818	F2958F	0.38
UCEC	chr5	14508366	Nonsense_Mutation	NA	R3080*	0.3
UCEC	chr5	14462839	Missense_Mutation	novel	E1861K	0.37
UCEC	chr5	14401055	Silent	novel	I1569I	0.44
UCEC	chr5	14508072	Missense_Mutation	novel	T2982A	0.24
UCEC	chr5	14290749	Missense_Mutation	NA	V192I	0.39
UCEC	chr5	14485130	Missense_Mutation	NA	S2240L	0.08
UCEC	chr5	14488903	Intron	rs759808480		0.43
UCEC	chr5	14508206	Silent	rs200447498	F3026F	0.37
UCEC	chr5	14441321	Intron	novel		0.55
UCEC	chr5	14406575	Missense_Mutation	rs751338228	D1621G	0.58
UCEC	chr5	14290806	Missense_Mutation	rs538529734	E211K	0.12
UCEC	chr5	14387792	Nonsense_Mutation	NA	R1276*	0.27
UCEC	chr5	14471402	Missense_Mutation	NA	L1950I	0.32
UCEC	chr5	14479327	Missense_Mutation	NA	E2074K	0.23
UCEC	chr5	14508447	3'UTR	novel		0.17
UCEC	chr5	14496890	Missense_Mutation	novel	S2631Y	0.13
UCEC	chr5	14359374	Missense_Mutation	novel	S745N	0.5
UCEC	chr5	14387517	Frame_Shift_Ins	NA	*C1220Mfs7**	0.54
UCEC	chr5	14387517	Frame_Shift_Ins	NA	*C1220Mfs7**	0.27
UCEC	chr5	14508816	3'UTR	novel		0.77
UCEC	chr5	14489147	Intron	novel		0.2
UCEC	chr5	14508206	Silent	rs200447498	F3026F	0.33
UCEC	chr5	14508678	3'UTR	novel		0.25
UCEC	chr5	14498630	Silent	NA	L2774L	0.37
UCEC	chr5	14489166	Intron	novel		0.52
UCEC	chr5	14406604	Missense_Mutation	NA	G1631S	0.42
UCEC	chr5	14359532	Splice_Site	NA	X797_splice	0.42
UCEC	chr5	14479931	Missense_Mutation	rs781722470	R2086C	0.13
UCEC	chr5	14359367	Missense_Mutation	novel	I743V	0.33
UCEC	chr5	14400987	Missense_Mutation	novel	H1547Y	0.42
UCEC	chr5	14479321	Missense_Mutation	novel	V2072I	0.35
UCEC	chr5	14336659	Missense_Mutation	novel	V660I	0.41
UCEC	chr5	14507939	Silent	novel	F2937F	0.39
UCEC	chr5	14290806	Missense_Mutation	rs538529734	E211K	0.37
UCEC	chr5	14476895	Frame_Shift_Del	rs752676391	L2031*	0.41
UCEC	chr5	14387777	Missense_Mutation	NA	S1271A	0.2
UCEC	chr5	14462838	Silent	rs146544278	G1860G	0.18
UCEC	chr5	14363788	Silent	rs758409767	F816F	0.27
UCEC	chr5	14482698	Silent	rs139448086	I2194I	0.29
UCEC	chr5	14398960	Nonsense_Mutation	NA	R1502*	0.31
UCEC	chr5	14508002	Silent	rs572269818	F2958F	0.33
UCEC	chr5	14509282	3'UTR	novel		0.43
UCEC	chr5	14286988	Silent	novel	V155V	0.28
UCEC	chr5	14286989	Missense_Mutation	novel	A156T	0.47
UCEC	chr5	14387631	Missense_Mutation	rs201215276	S1255L	0.51
UCEC	chr5	14390246	Missense_Mutation	novel	E1358D	0.18
UCEC	chr5	14398960	Nonsense_Mutation	NA	R1502*	0.24
UCEC	chr5	14419888	Silent	novel	H1690H	0.27
UCEC	chr5	14462817	Missense_Mutation	novel	Q1853H	0.25
UCEC	chr5	14465689	Intron	novel		0.13
UCEC	chr5	14471415	Missense_Mutation	novel	S1954L	0.34
UCEC	chr5	14482590	Silent	rs754779359	I2158I	0.65
UCEC	chr5	14492569	Splice_Region	novel	S2545S	0.25
UCEC	chr5	14498160	Nonsense_Mutation	rs747166529	R2707*	0.33
UCEC	chr5	14508595	3'UTR	novel		0.68
UCEC	chr5	14465788	Intron	novel		0.07
UCEC	chr5	14316555	Missense_Mutation	novel	P515S	0.43
UCEC	chr5	14389386	Missense_Mutation	novel	E1349G	0.31
UCEC	chr5	14336666	Missense_Mutation	NA	R662H	0.09
UCEC	chr5	14316599	Silent	novel	N529N	0.31
UCEC	chr5	14286892	Silent	novel	G123G	0.09
UCEC	chr5	14366862	Splice_Region	NA	V919V	0.17
UCEC	chr5	14359506	Missense_Mutation	NA	R789H	0.28
UCEC	chr5	14358246	Silent	rs747272635	A705A	0.43
UCEC	chr5	14488890	Intron	novel		0.36
UCEC	chr5	14368725	Silent	novel	A964A	0.56
UCEC	chr5	14387553	Missense_Mutation	novel	R1229I	0.39
UCEC	chr5	14390966	Silent	novel	L1398L	0.28
UCEC	chr5	14398975	Missense_Mutation	novel	R1507W	0.23
UCEC	chr5	14419851	Missense_Mutation	novel	R1678Q	0.37
UCEC	chr5	14479309	Missense_Mutation	novel	S2068P	0.37
UCEC	chr5	14492797	Silent	rs754877810	N2621N	0.29
UCEC	chr5	14489166	Intron	novel		0.71
UCS	chr5	14487495	Missense_Mutation	novel	N2289K	0.1
UCS	chr5	14508437	3'UTR	rs761742565		0.36
UVM	chr5	14508240	Missense_Mutation	novel	R3038C	0.13

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	DEL	0.0243	0.09673
SKCM	DEL	0.1526	0.011094
TGCT	DEL	0.5733	0.098913
THCA	DEL	0.004	0.23456

Survival Analysis

Cancer	P-value	Q-value
THYM	0.04	Kaplan-Meier Survival Analysis
SARC	0.006	Kaplan-Meier Survival Analysis
MESO	0.00057	Kaplan-Meier Survival Analysis
ACC	0.027	Kaplan-Meier Survival Analysis
SKCM	0.0037	Kaplan-Meier Survival Analysis
ESCA	0.0069	Kaplan-Meier Survival Analysis
KIRP	0.0062	Kaplan-Meier Survival Analysis
CESC	0.0069	Kaplan-Meier Survival Analysis
UCEC	0.00017	Kaplan-Meier Survival Analysis
LIHC	0.0011	Kaplan-Meier Survival Analysis
LGG	0.00026	Kaplan-Meier Survival Analysis
THCA	0.0053	Kaplan-Meier Survival Analysis
UVM	0.01	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000038382 (Gene tree)
Gene ID: 7204
Gene Symbol: TRIO
Alias: ARHGEF23
Full Name: trio Rho guanine nucleotide exchange factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 388,427 bases
Position: chr5:14,143,702-14,532,128
Accession: 12303
RBP type: non-canonical RBP
Summary: This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.