EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21252116	IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2.	Cancer Res	2011 Mar 15	Mongroo PS	doi: 10.1158/0008-5472.CAN-10-3295

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr5	157319903	Missense_Mutation	NA	R500W	0.42
ACC	chr5	157300742	Missense_Mutation	novel	E139K	0.11
ACC	chr5	157326253	Nonsense_Mutation	novel	E714*	0.16
BLCA	chr5	157359145	Silent	novel	S963S	0.5
BLCA	chr5	157361574	Missense_Mutation	novel	F1030L	0.14
BLCA	chr5	157300855	Missense_Mutation	novel	N176K	0.23
BLCA	chr5	157361509	Missense_Mutation	novel	E1009K	0.39
BLCA	chr5	157294794	Silent	novel	L73L	0.14
BLCA	chr5	157294795	Nonsense_Mutation	novel	E74*	0.14
BLCA	chr5	157392841	Missense_Mutation	novel	K1226N	0.38
BLCA	chr5	157320776	Missense_Mutation	novel	R549C	0.35
BLCA	chr5	157314446	Missense_Mutation	rs775941668	A405T	0.12
BLCA	chr5	157320755	Missense_Mutation	novel	F542L	0.74
BRCA	chr5	157325556	Missense_Mutation	NA	R659G	0.58
BRCA	chr5	157390662	Missense_Mutation	NA	K1221N	0.25
BRCA	chr5	157294848	Silent	novel	R91R	0.06
BRCA	chr5	157333447	Splice_Site	novel	X820_splice	0.09
BRCA	chr5	157390660	Frame_Shift_Del	NA	*K1221Mfs4**	0.15
BRCA	chr5	157319903	Missense_Mutation	NA	R500W	0.19
BRCA	chr5	157307859	Missense_Mutation	novel	F298L	0.09
BRCA	chr5	157320671	Nonsense_Mutation	NA	R514*	0.23
BRCA	chr5	157339086	Silent	novel	R830R	0.07
BRCA	chr5	157359022	Silent	rs775411906	Y922Y	0.31
BRCA	chr5	157319880	Missense_Mutation	rs755329609	R492H	0.18
BRCA	chr5	157333399	Missense_Mutation	NA	D805Y	0.24
CESC	chr5	157285394	Silent	novel	L11L	0.09
CESC	chr5	157322959	Silent	novel	P563P	0.27
CESC	chr5	157341111	Missense_Mutation	NA	R901Q	0.51
CESC	chr5	157390630	Nonsense_Mutation	novel	Q1211*	0.54
CESC	chr5	157294780	Splice_Region	novel		0.12
CESC	chr5	157309770	Missense_Mutation	novel	D310N	0.44
CESC	chr5	157320702	Missense_Mutation	rs746795054	R524Q	0.27
CESC	chr5	157296703	Missense_Mutation	novel	E106Q	0.13
CHOL	chr5	157319891	Missense_Mutation	NA	R496W	0.25
COAD	chr5	157300860	Missense_Mutation	novel	K178R	0.21
COAD	chr5	157296685	Missense_Mutation	rs753263281	E100K	0.37
COAD	chr5	157319855	Frame_Shift_Ins	novel	*Q484Rfs7**	0.08
COAD	chr5	157319857	In_Frame_Ins	novel	Q484_D485insN	0.06
COAD	chr5	157325600	Silent	novel	T673T	0.12
COAD	chr5	157339131	Silent	rs761084028	F845F	0.12
COAD	chr5	157300758	Missense_Mutation	novel	C144Y	0.29
COAD	chr5	157382601	Missense_Mutation	NA	E1042D	0.32
COAD	chr5	157383319	Missense_Mutation	novel	L1081P	0.23
COAD	chr5	157389329	Silent	rs769817015	G1141G	0.17
COAD	chr5	157285436	Silent	novel	Q25Q	0.3
COAD	chr5	157325556	Nonsense_Mutation	NA	R659*	0.39
COAD	chr5	157333441	Missense_Mutation	novel	I819V	0.37
COAD	chr5	157307829	Missense_Mutation	novel	K288N	0.29
COAD	chr5	157341133	Silent	novel	Q908Q	0.21
COAD	chr5	157341083	Missense_Mutation	NA	A892T	0.29
COAD	chr5	157339128	Missense_Mutation	novel	S844R	0.2
COAD	chr5	157296705	Silent	novel	E106E	0.07
COAD	chr5	157315053	Missense_Mutation	NA	R439C	0.25
COAD	chr5	157389250	Missense_Mutation	novel	S1115F	0.09
COAD	chr5	157392952	Silent	novel	V1263V	0.28
COAD	chr5	157320671	Nonsense_Mutation	NA	R514*	0.36
COAD	chr5	157307842	Missense_Mutation	novel	S293G	0.18
COAD	chr5	157320701	Nonsense_Mutation	NA	R524*	0.26
COAD	chr5	157319845	Silent	novel	Y480Y	0.1
COAD	chr5	157392953	Missense_Mutation	rs371399881	R1264C	0.19
COAD	chr5	157339119	Silent	rs371132555	T841T	0.16
ESCA	chr5	157360299	Silent	novel	L970L	0.58
ESCA	chr5	157300789	Silent	novel	S154S	0.24
ESCA	chr5	157325507	Silent	rs367974123	L642L	0.2
ESCA	chr5	157319874	Missense_Mutation	novel	T490M	0.1
ESCA	chr5	157304437	Intron	novel		0.22
GBM	chr5	157324029	Missense_Mutation	novel	F619I	0.2
GBM	chr5	157361471	Missense_Mutation	novel	I996T	0.23
GBM	chr5	157339158	Silent	novel	H854H	0.08
HNSC	chr5	157359079	Silent	novel	I941I	0.41
HNSC	chr5	157333398	Silent	novel	L804L	0.26
HNSC	chr5	157326265	Missense_Mutation	novel	E718K	0.16
HNSC	chr5	157314385	Silent	rs761547295	E384E	0.39
HNSC	chr5	157296760	Missense_Mutation	novel	F125L	0.34
HNSC	chr5	157359021	Missense_Mutation	novel	Y922C	0.32
HNSC	chr5	157294841	Missense_Mutation	novel	C89S	0.35
HNSC	chr5	157311734	Missense_Mutation	novel	D355Y	0.33
HNSC	chr5	157324052	Silent	novel	F626F	0.74
HNSC	chr5	157389390	Missense_Mutation	novel	Y1162N	0.3
HNSC	chr5	157326232	Nonsense_Mutation	novel	K707*	0.73
KIRC	chr5	157319788	Silent	novel	Q461Q	0.35
KIRC	chr5	157383289	Missense_Mutation	novel	M1071R	0.15
KIRC	chr5	157323955	Missense_Mutation	novel	I594T	0.13
KIRC	chr5	157326221	Missense_Mutation	novel	L703P	0.21
KIRP	chr5	157311667	Missense_Mutation	novel	W332C	0.31
LGG	chr5	157294846	Missense_Mutation	novel	R91W	0.11
LGG	chr5	157300716	Missense_Mutation	novel	R130H	0.5
LGG	chr5	157323988	Missense_Mutation	novel	R605M	0.43
LGG	chr5	157330827	Silent	novel	L773L	0.07
LGG	chr5	157393119	3'UTR	novel		0.2
LIHC	chr5	157389329	Silent	rs769817015	G1141G	0.24
LIHC	chr5	157392918	Missense_Mutation	novel	S1252Y	0.18
LIHC	chr5	157300765	Silent	novel	A146A	0.66
LIHC	chr5	157328015	Missense_Mutation	NA	Q733E	0.18
LIHC	chr5	157389267	Silent	NA	L1121L	0.61
LIHC	chr5	157285338	Splice_Site	novel		0.16
LIHC	chr5	157341079	Silent	NA	R890R	0.17
LUAD	chr5	157383282	Missense_Mutation	novel	V1069F	0.35
LUAD	chr5	157304341	Missense_Mutation	novel	P257R	0.09
LUAD	chr5	157328049	Missense_Mutation	NA	S744I	0.29
LUAD	chr5	157304405	Intron	novel		0.15
LUAD	chr5	157319818	Silent	novel	F471F	0.1
LUAD	chr5	157359035	Missense_Mutation	novel	S927C	0.22
LUAD	chr5	157325613	Missense_Mutation	novel	E678K	0.22
LUAD	chr5	157392953	Missense_Mutation	rs371399881	R1264C	0.43
LUAD	chr5	157285405	Missense_Mutation	novel	D15A	0.32
LUAD	chr5	157360313	Missense_Mutation	NA	T975I	0.16
LUAD	chr5	157304366	Missense_Mutation	novel	K265N	0.33
LUAD	chr5	157339092	Silent	rs369405267	T832T	0.22
LUAD	chr5	157341101	Nonsense_Mutation	novel	E898*	0.17
LUAD	chr5	157324003	Missense_Mutation	NA	G610V	0.5
LUAD	chr5	157360315	Silent	novel	L976L	0.42
LUSC	chr5	157320723	Missense_Mutation	novel	C531S	0.43
LUSC	chr5	157360288	Missense_Mutation	novel	G967R	0.25
LUSC	chr5	157359056	Missense_Mutation	novel	G934R	0.17
LUSC	chr5	157328018	Missense_Mutation	novel	I734V	0.25
LUSC	chr5	157341120	Frame_Shift_Ins	novel	*A905Cfs86**	0.56
LUSC	chr5	157341122	Missense_Mutation	novel	A905P	0.55
LUSC	chr5	157319863	Silent	rs563909737	F486F	0.74
LUSC	chr5	157360360	Missense_Mutation	novel	Y991N	0.55
LUSC	chr5	157392901	Silent	novel	L1246L	0.21
LUSC	chr5	157339084	Silent	novel	R830R	0.25
LUSC	chr5	157304310	Missense_Mutation	novel	D247Y	0.28
LUSC	chr5	157320715	Missense_Mutation	novel	N528K	0.41
LUSC	chr5	157330799	Silent	rs141399379	P763P	0.25
LUSC	chr5	157383359	In_Frame_Ins	novel	Q1095_G1102dup	0.1
LUSC	chr5	157304423	Intron	novel		0.07
LUSC	chr5	157339138	Missense_Mutation	novel	M848V	0.59
LUSC	chr5	157361518	Missense_Mutation	novel	E1012Q	0.11
LUSC	chr5	157383354	Missense_Mutation	novel	P1093A	0.65
LUSC	chr5	157360308	Silent	novel	V973V	0.18
OV	chr5	157341096	Missense_Mutation	novel	T896S	0.2
OV	chr5	157311777	Missense_Mutation	novel	S369I	0.5
OV	chr5	157314436	Silent	novel	S401S	0.11
OV	chr5	157326235	Missense_Mutation	novel	K708Q	0.06
OV	chr5	157304418	Intron	novel		0.1
OV	chr5	157339225	Missense_Mutation	novel	P877T	0.12
PAAD	chr5	157314981	Missense_Mutation	novel	L415M	0.19
PAAD	chr5	157319863	Silent	rs563909737	F486F	0.16
PAAD	chr5	157320671	Nonsense_Mutation	NA	R514*	0.19
PRAD	chr5	157307864	Missense_Mutation	novel	K300M	0.44
PRAD	chr5	157319761	Splice_Site	NA	X453_splice	0.16
PRAD	chr5	157314345	Missense_Mutation	NA	V371A	0.11
PRAD	chr5	157389231	Missense_Mutation	novel	R1109W	0.52
PRAD	chr5	157389374	Silent	rs774406650	S1156S	0.33
READ	chr5	157392851	Missense_Mutation	rs749706783	D1230N	0.29
READ	chr5	157393153	3'UTR	novel		0.2
READ	chr5	157304313	Missense_Mutation	novel	Y248H	0.12
READ	chr5	157359107	Missense_Mutation	NA	A951T	0.22
READ	chr5	157339131	Silent	rs761084028	F845F	0.49
READ	chr5	157359052	Silent	rs764090706	F932F	0.35
READ	chr5	157330760	Silent	novel	R750R	0.08
READ	chr5	157389386	Silent	rs267600516	F1160F	0.27
SARC	chr5	157383360	Splice_Site	novel	X1094_splice	0.26
SARC	chr5	157333411	Missense_Mutation	novel	S809G	0.31
SARC	chr5	157330758	Missense_Mutation	rs535692197	R750C	0.26
SARC	chr5	157324043	In_Frame_Del	novel	F626del	0.22
SARC	chr5	157393077	3'UTR	novel		0.26
SKCM	chr5	157389263	Silent	novel	V1119V	0.19
SKCM	chr5	157300760	Missense_Mutation	novel	H145Y	0.88
SKCM	chr5	157320699	Missense_Mutation	novel	G523E	0.29
SKCM	chr5	157320763	Silent	novel	I544I	0.4
SKCM	chr5	157389398	Silent	novel	I1164I	0.24
SKCM	chr5	157359046	Silent	novel	R930R	0.39
SKCM	chr5	157319773	Missense_Mutation	novel	M456I	0.27
SKCM	chr5	157304360	Silent	novel	L263L	0.25
SKCM	chr5	157314417	Missense_Mutation	novel	R395Q	0.41
SKCM	chr5	157314996	Missense_Mutation	novel	D420N	0.38
SKCM	chr5	157359052	Silent	rs764090706	F932F	0.05
SKCM	chr5	157361571	Silent	novel	L1029L	0.34
SKCM	chr5	157314395	Missense_Mutation	rs267600515	E388K	0.31
SKCM	chr5	157315088	Silent	rs561569282	F450F	0.26
SKCM	chr5	157320671	Nonsense_Mutation	NA	R514*	0.32
SKCM	chr5	157360332	Silent	rs754292659	P981P	0.32
SKCM	chr5	157389414	Missense_Mutation	NA	E1170K	0.25
SKCM	chr5	157393034	3'UTR	novel		0.33
SKCM	chr5	157383354	Missense_Mutation	novel	P1093S	0.12
SKCM	chr5	157315074	Missense_Mutation	novel	E446K	0.27
SKCM	chr5	157361469	Splice_Region	novel	G995G	0.43
SKCM	chr5	157361484	Silent	novel	F1000F	0.58
SKCM	chr5	157383354	Missense_Mutation	novel	P1093S	0.53
SKCM	chr5	157307788	Missense_Mutation	novel	D275N	0.43
SKCM	chr5	157389266	Silent	novel	I1120I	0.23
SKCM	chr5	157325581	Missense_Mutation	novel	S667F	0.13
SKCM	chr5	157315028	Silent	rs746132709	T430T	0.56
SKCM	chr5	157296685	Missense_Mutation	rs753263281	E100K	0.51
SKCM	chr5	157359123	Missense_Mutation	novel	E956V	0.4
SKCM	chr5	157359149	Splice_Site	novel	X964_splice	0.9
SKCM	chr5	157320682	Silent	novel	I517I	0.45
SKCM	chr5	157307859	Silent	rs773194413	F298F	0.27
SKCM	chr5	157389386	Silent	rs267600516	F1160F	0.16
SKCM	chr5	157311743	Missense_Mutation	novel	R358C	0.2
SKCM	chr5	157330847	Silent	novel	V779V	0.18
SKCM	chr5	157339185	Silent	novel	I863I	0.29
SKCM	chr5	157309800	Nonsense_Mutation	rs3207362	K320*	0.12
SKCM	chr5	157361469	Splice_Region	novel	G995G	0.16
SKCM	chr5	157314435	Missense_Mutation	NA	S401F	0.08
SKCM	chr5	157294785	Missense_Mutation	novel	N70K	0.34
SKCM	chr5	157302825	Missense_Mutation	novel	P201S	0.09
SKCM	chr5	157325567	Silent	novel	F662F	0.16
SKCM	chr5	157330815	Missense_Mutation	rs770698075	R769C	0.13
SKCM	chr5	157296733	Missense_Mutation	novel	E116K	0.17
SKCM	chr5	157314418	Silent	novel	R395R	0.33
SKCM	chr5	157359088	Silent	rs751738375	L944L	0.35
SKCM	chr5	157319863	Silent	rs563909737	F486F	0.44
SKCM	chr5	157314386	Missense_Mutation	novel	E385K	0.46
SKCM	chr5	157390530	Silent	novel	F1177F	0.43
SKCM	chr5	157389377	Silent	novel	A1157A	0.17
SKCM	chr5	157389251	Silent	novel	S1115S	0.45
SKCM	chr5	157389359	Silent	novel	F1151F	0.39
SKCM	chr5	157361581	Missense_Mutation	NA	L1033F	0.16
SKCM	chr5	157333394	Missense_Mutation	novel	S803F	0.31
SKCM	chr5	157383255	Intron	novel		0.24
SKCM	chr5	157319807	Missense_Mutation	novel	E468K	0.85
SKCM	chr5	157314457	Missense_Mutation	novel	M408I	0.13
SKCM	chr5	157389232	Missense_Mutation	novel	R1109P	0.56
SKCM	chr5	157390602	Silent	rs200774279	F1201F	0.34
SKCM	chr5	157319833	Silent	novel	R476R	0.26
SKCM	chr5	157341089	Missense_Mutation	novel	P894S	0.28
SKCM	chr5	157389405	Missense_Mutation	novel	G1167R	0.33
SKCM	chr5	157392919	Silent	rs771500468	S1252S	0.28
SKCM	chr5	157383273	Missense_Mutation	novel	R1066G	0.38
SKCM	chr5	157339132	Missense_Mutation	rs776958013	D846N	0.16
STAD	chr5	157325559	Missense_Mutation	NA	I660V	0.51
STAD	chr5	157359048	Missense_Mutation	NA	N931T	0.17
STAD	chr5	157328020	Silent	novel	I734I	0.19
STAD	chr5	157389258	Missense_Mutation	NA	E1118K	0.17
STAD	chr5	157326267	Splice_Region	NA	E718E	0.13
STAD	chr5	157304287	Missense_Mutation	novel	A239V	0.15
STAD	chr5	157341077	Missense_Mutation	NA	R890W	0.14
STAD	chr5	157389205	Missense_Mutation	NA	R1100H	0.19
STAD	chr5	157389375	Missense_Mutation	rs369611074	A1157T	0.22
STAD	chr5	157300735	Missense_Mutation	novel	F136L	0.25
STAD	chr5	157383304	Missense_Mutation	NA	A1076V	0.22
STAD	chr5	157307831	Missense_Mutation	novel	R289I	0.53
STAD	chr5	157320676	Missense_Mutation	NA	K515N	0.34
STAD	chr5	157359107	Missense_Mutation	NA	A951T	0.34
STAD	chr5	157311728	Missense_Mutation	NA	R353W	0.36
STAD	chr5	157304442	Intron	novel		0.33
STAD	chr5	157315087	Missense_Mutation	novel	F450C	0.23
STAD	chr5	157339126	Missense_Mutation	NA	S844G	0.14
STAD	chr5	157320701	Nonsense_Mutation	NA	R524*	0.08
STAD	chr5	157304403	Intron	novel		0.13
STAD	chr5	157325555	Silent	NA	R658R	0.34
STAD	chr5	157294840	Missense_Mutation	novel	C89G	0.12
STAD	chr5	157393061	3'UTR	novel		0.47
STAD	chr5	157389386	Silent	rs267600516	F1160F	0.23
STAD	chr5	157389330	Missense_Mutation	rs764457342	V1142I	0.45
STAD	chr5	157319864	Missense_Mutation	novel	A487T	0.41
THYM	chr5	157285376	Silent	novel	V5V	0.25
UCEC	chr5	157320773	Missense_Mutation	novel	R548W	0.41
UCEC	chr5	157309766	Silent	rs539257822	F308F	0.36
UCEC	chr5	157314369	Missense_Mutation	novel	S379N	0.33
UCEC	chr5	157361549	Missense_Mutation	novel	R1022M	0.18
UCEC	chr5	157339096	Missense_Mutation	rs780950093	R834W	0.27
UCEC	chr5	157307831	Missense_Mutation	novel	R289I	0.26
UCEC	chr5	157320671	Nonsense_Mutation	NA	R514*	0.31
UCEC	chr5	157330765	Missense_Mutation	rs765425949	R752Q	0.35
UCEC	chr5	157333364	Missense_Mutation	novel	T793I	0.25
UCEC	chr5	157315088	Silent	rs561569282	F450F	0.32
UCEC	chr5	157389386	Silent	rs267600516	F1160F	0.32
UCEC	chr5	157390642	Missense_Mutation	novel	G1215W	0.18
UCEC	chr5	157314381	Missense_Mutation	rs760152670	D383G	0.17
UCEC	chr5	157323968	Silent	rs764499380	S598S	0.1
UCEC	chr5	157339098	Silent	novel	R834R	0.33
UCEC	chr5	157389366	Missense_Mutation	novel	L1154M	0.39
UCEC	chr5	157395280	3'Flank	novel		0.44
UCEC	chr5	157320671	Nonsense_Mutation	NA	R514*	0.09
UCEC	chr5	157325622	Nonsense_Mutation	novel	E681*	0.37
UCEC	chr5	157307765	Missense_Mutation	novel	M267T	0.4
UCEC	chr5	157302873	Missense_Mutation	novel	H217Y	0.49
UCEC	chr5	157395633	3'Flank	novel		0.4
UCEC	chr5	157311712	Silent	rs373676501	E347E	0.07
UCEC	chr5	157330844	Silent	rs771980621	H778H	0.46
UCEC	chr5	157300716	Missense_Mutation	novel	R130H	0.16
UCEC	chr5	157359052	Silent	rs764090706	F932F	0.25
UCEC	chr5	157360343	Missense_Mutation	novel	R985H	0.34
UCEC	chr5	157393092	3'UTR	novel		0.36
UCEC	chr5	157311712	Missense_Mutation	novel	E347D	0.16
UCEC	chr5	157314392	Missense_Mutation	rs750246368	R387C	0.28
UCEC	chr5	157304318	Silent	rs758449124	Y249Y	0.23
UCEC	chr5	157319866	Silent	novel	A487A	0.2
UCEC	chr5	157294835	Missense_Mutation	novel	R87H	0.18
UCEC	chr5	157325556	Nonsense_Mutation	NA	R659*	0.27
UCEC	chr5	157339132	Missense_Mutation	rs776958013	D846N	0.3
UCEC	chr5	157382607	Silent	novel	C1044C	0.09
UCEC	chr5	157333395	Silent	novel	S803S	0.2
UCEC	chr5	157360369	Missense_Mutation	novel	P994T	0.17
UCEC	chr5	157383285	Missense_Mutation	rs764928113	R1070W	0.1
UCEC	chr5	157383274	Missense_Mutation	novel	R1066H	0.34
UCEC	chr5	157311670	Silent	rs745838142	T333T	0.06
UCEC	chr5	157389257	Silent	rs549574042	F1117F	0.29
UCEC	chr5	157323951	Missense_Mutation	novel	L593F	0.41
UCEC	chr5	157307813	Missense_Mutation	novel	K283R	0.47
UCEC	chr5	157314431	Missense_Mutation	novel	L400I	0.33
UCEC	chr5	157339144	Nonsense_Mutation	novel	R850*	0.32
UCEC	chr5	157341072	Missense_Mutation	novel	F888C	0.53
UCEC	chr5	157359079	Silent	novel	I941I	0.47
UCEC	chr5	157390656	Silent	novel	I1219I	0.38
UCEC	chr5	157296714	Silent	novel	E109E	0.67
UCEC	chr5	157325557	Missense_Mutation	novel	R659Q	0.36
UCEC	chr5	157395273	3'Flank	novel		0.33
UCEC	chr5	157395598	3'Flank	novel		0.41
UCEC	chr5	157304404	Intron	novel		0.44
UCEC	chr5	157302864	Missense_Mutation	novel	L214M	0.23
UCEC	chr5	157323974	Silent	novel	S600S	0.27
UCEC	chr5	157392860	Missense_Mutation	novel	R1233G	0.33
UCEC	chr5	157395679	3'Flank	novel		0.25
UCEC	chr5	157320787	Silent	novel	G552G	0.32
UCEC	chr5	157300716	Missense_Mutation	novel	R130H	0.45
UCEC	chr5	157314393	Missense_Mutation	rs758334790	R387H	0.37
UCEC	chr5	157319849	Missense_Mutation	novel	A482S	0.41
UCEC	chr5	157341110	Nonsense_Mutation	novel	R901*	0.42
UCEC	chr5	157395281	3'Flank	novel		0.5
UCEC	chr5	157324055	Silent	novel	T627T	0.49
UCEC	chr5	157330787	Silent	rs374669553	G759G	0.39
UCEC	chr5	157345723	Intron	novel		0.33
UCEC	chr5	157328041	Missense_Mutation	rs764101175	M741I	0.48
UCEC	chr5	157339143	Silent	novel	F849F	0.57
UCEC	chr5	157300727	Missense_Mutation	novel	E134K	0.41
UCEC	chr5	157383285	Missense_Mutation	rs764928113	R1070W	0.21
UCEC	chr5	157361514	Silent	rs377070210	Y1010Y	0.26
UCEC	chr5	157341072	Missense_Mutation	novel	F888C	0.37
UCEC	chr5	157395283	3'Flank	novel		0.42
UCEC	chr5	157294862	Splice_Site	novel	X95_splice	0.37
UCEC	chr5	157383273	Missense_Mutation	rs763607353	R1066C	0.31
UCEC	chr5	157395525	3'Flank	novel		0.44
UCEC	chr5	157309766	Silent	rs539257822	F308F	0.36
UCEC	chr5	157320777	Missense_Mutation	novel	R549H	0.34
UCEC	chr5	157389330	Missense_Mutation	rs764457342	V1142I	0.44
UCEC	chr5	157304340	Missense_Mutation	novel	P257T	0.06
UCEC	chr5	157323969	Missense_Mutation	novel	G599S	0.17
UCEC	chr5	157392888	Frame_Shift_Del	novel	*F1243Lfs4**	0.49
UCEC	chr5	157320672	Missense_Mutation	NA	R514Q	0.24
UCEC	chr5	157359052	Silent	rs764090706	F932F	0.33
UCEC	chr5	157296697	Nonsense_Mutation	novel	R104*	0.35
UCEC	chr5	157314445	Silent	rs559404174	S404S	0.36
UCEC	chr5	157325586	Missense_Mutation	novel	P669S	0.34
UCEC	chr5	157315056	Missense_Mutation	novel	Y440H	0.35
UCEC	chr5	157390586	Missense_Mutation	rs780179999	R1196H	0.23
UCEC	chr5	157300766	Missense_Mutation	rs779775850	E147K	0.52
UCEC	chr5	157359006	Missense_Mutation	novel	P917L	0.04
UCEC	chr5	157360352	Missense_Mutation	novel	R988Q	0.07
UCEC	chr5	157339168	Missense_Mutation	rs377031549	A858T	0.26
UCEC	chr5	157325557	Missense_Mutation	novel	R659Q	0.14
UCEC	chr5	157383338	Silent	rs747475869	I1087I	0.49
UCEC	chr5	157287085	Nonsense_Mutation	novel	Q62*	0.3
UCEC	chr5	157320701	Nonsense_Mutation	NA	R524*	0.68
UCEC	chr5	157319768	Missense_Mutation	novel	A455T	0.34
UCEC	chr5	157320736	Missense_Mutation	novel	E535D	0.47
UCEC	chr5	157359052	Silent	rs764090706	F932F	0.2
UCEC	chr5	157323991	Missense_Mutation	novel	S606I	0.32
UCEC	chr5	157330792	Missense_Mutation	novel	I761S	0.28
UCEC	chr5	157339107	Silent	novel	C837C	0.3
UCEC	chr5	157325626	Missense_Mutation	novel	P682H	0.15
UCEC	chr5	157326208	Missense_Mutation	rs566311656	A699T	0.16
UCEC	chr5	157389341	Silent	rs750011023	V1145V	0.21
UCEC	chr5	157320672	Missense_Mutation	NA	R514Q	0.26
UCEC	chr5	157389257	Silent	rs549574042	F1117F	0.41
UCEC	chr5	157390530	Silent	novel	F1177F	0.42
UCEC	chr5	157323977	Missense_Mutation	novel	K601N	0.45
UCEC	chr5	157390640	Missense_Mutation	novel	D1214G	0.44
UCEC	chr5	157314351	Missense_Mutation	rs772567936	T373M	0.48
UCEC	chr5	157395282	3'Flank	novel		0.57
UCEC	chr5	157302863	Missense_Mutation	novel	F213L	0.43
UCEC	chr5	157315089	Missense_Mutation	novel	V451I	0.4
UCEC	chr5	157320742	Silent	rs776519767	D537D	0.35
UCS	chr5	157285404	Missense_Mutation	novel	D15N	0.6
UCS	chr5	157330764	Nonsense_Mutation	NA	R752*	0.24
UCS	chr5	157389414	Missense_Mutation	NA	E1170K	0.42

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	AMP	0.1042	0.069756
KIRP	DEL	0.0382	0.11554
LGG	DEL	0.0936	1.86e-07
LUSC	DEL	0.6208	0.002071
MESO	DEL	0.1724	0.20184
PRAD	AMP	0.0346	0.16448
SKCM	DEL	0.2997	2.2081e-08
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0013	Kaplan-Meier Survival Analysis
SARC	0.0045	Kaplan-Meier Survival Analysis
HNSC	0.0089	Kaplan-Meier Survival Analysis
SKCM	0.00037	Kaplan-Meier Survival Analysis
LUSC	0.041	Kaplan-Meier Survival Analysis
KIRP	0.0057	Kaplan-Meier Survival Analysis
PAAD	0.00012	Kaplan-Meier Survival Analysis
BLCA	0.015	Kaplan-Meier Survival Analysis
UCEC	0.0001	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
LUAD	0.0019	Kaplan-Meier Survival Analysis
UVM	0.01	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000055163 (Gene tree)
Gene ID: 26999
Gene Symbol: CYFIP2
Alias: PIR121
Full Name: cytoplasmic FMR1 interacting protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 129,520 bases
Position: chr5:157,266,079-157,395,598
Accession: 13760
RBP type: non-canonical RBP
Summary: (Cytoplasmic FMR1 Interacting Protein 2) is a Protein Coding gene. Diseases associated with CYFIP2 include Epileptic Encephalopathy, Early Infantile, 65 and Undetermined Early-Onset Epileptic Encephalopathy. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include chemokine activity. An important paralog of this gene is CYFIP1.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22430187	Two potential biomarkers identified in mesenchymal stem cells and leukocytes of patients with sporadic amyotrophic lateral sclerosis.	Dis Markers	2012	Nachmany H	doi: 10.3233/DMA-2011-0885.
30982501	Neuronal function and dysfunction of CYFIP2: from actin dynamics to early infantile epileptic encephalopathy.	BMB Rep	2019 May	Zhang Y	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000617629	CYFIP2-220	967	-	ENSP00000480605	295 (aa)	-	A0A087WWZ1
ENST00000522463	CYFIP2-210	3477	-	ENSP00000428009	1057 (aa)	-	E7EW33
ENST00000618329	CYFIP2-221	4256	XM_011534516	ENSP00000484819	1253 (aa)	XP_011532818	Q96F07
ENST00000521420	CYFIP2-209	6370	-	ENSP00000430904	1227 (aa)	-	E7EVJ5
ENST00000435847	CYFIP2-201	3673	-	ENSP00000403793	1117 (aa)	-	H7C229
ENST00000616178	CYFIP2-219	4210	-	ENSP00000479719	1278 (aa)	-	Q96F07
ENST00000523383	CYFIP2-215	916	-	-	- (aa)	-	-
ENST00000522884	CYFIP2-213	579	-	-	- (aa)	-	-
ENST00000611075	CYFIP2-217	1000	-	ENSP00000479376	188 (aa)	-	A0A087WVE1
ENST00000518456	CYFIP2-202	377	-	-	- (aa)	-	-
ENST00000520424	CYFIP2-206	579	-	-	- (aa)	-	-
ENST00000518511	CYFIP2-203	409	-	-	- (aa)	-	-
ENST00000518555	CYFIP2-204	745	-	-	- (aa)	-	-
ENST00000519663	CYFIP2-205	892	-	-	- (aa)	-	-
ENST00000520960	CYFIP2-208	576	-	ENSP00000482739	101 (aa)	-	A0A087WZL7
ENST00000520942	CYFIP2-207	771	-	-	- (aa)	-	-
ENST00000620254	CYFIP2-222	4124	XM_017009342	ENSP00000479968	1253 (aa)	XP_016864831	Q96F07
ENST00000522892	CYFIP2-214	583	-	-	- (aa)	-	-
ENST00000621516	CYFIP2-223	915	-	ENSP00000479211	71 (aa)	-	A0A087WV63
ENST00000611925	CYFIP2-218	925	-	ENSP00000478058	222 (aa)	-	A0A087WTQ3
ENST00000524058	CYFIP2-216	562	-	-	- (aa)	-	-
ENST00000522775	CYFIP2-212	582	-	-	- (aa)	-	-
ENST00000522637	CYFIP2-211	580	-	ENSP00000428079	68 (aa)	-	E5RKA3
ENST00000622696	CYFIP2-224	1294	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000055163's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG
hsa04810	Regulation of actin cytoskeleton	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000055163	Body Height	4.60143470570884E-5	17903300
ENSG00000055163	Body Height	6.33167658214973E-6	17903300
ENSG00000055163	Body Height	1.60326945661308E-5	17903300
ENSG00000055163	Body Height	3.48822950220207E-5	17903300
ENSG00000055163	Body Height	5.46022975778104E-5	17903300
ENSG00000055163	Body Height	4.04314880344429E-5	17903300
ENSG00000055163	Body Height	2.88955969929283E-5	17903300
ENSG00000055163	Body Height	8.18219302516803E-5	17903300
ENSG00000055163	Body Weights and Measures	2.65738591305187E-5	17903300
ENSG00000055163	Body Weight	3.90550385800621E-5	17903300
ENSG00000055163	Body Weights and Measures	2.95379025572196E-5	17903300
ENSG00000055163	Body Weight	6.7000883835065E-6	17903300
ENSG00000055163	Body Weight	1.08250878154077E-5	17903300
ENSG00000055163	Receptors, Tumor Necrosis Factor	7.12717198981484E-5	17903293
ENSG00000055163	Cardiovascular Physiological Phenomena	7.8640000E-005	-
ENSG00000055163	Cardiovascular Physiological Phenomena	6.2580000E-005	-
ENSG00000055163	Child Development Disorders, Pervasive	1.8701000E-005	-
ENSG00000055163	Child Development Disorders, Pervasive	2.1602000E-005	-
ENSG00000055163	Dehydroepiandrosterone	2.0190000E-005	-
ENSG00000055163	Dehydroepiandrosterone	1.8350000E-005	-
ENSG00000055163	Immunoglobulins	5E-6	23382691
ENSG00000055163	Lung Volume Measurements	5E-13	28166213

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000055163	rs871012	5	157388755	C	IgG glycosylation	23382691	[0.084-0.21] unit increase	0.1473	EFO_0005193
ENSG00000055163	rs56686215	5	157316075	?	Gamma glutamyl transferase levels	29403010	[0.029-0.049] unit decrease novel	0.03928	EFO_0004532
ENSG00000055163	rs10515750	5	157383064	T	Lung function (FEV1/FVC)	28166213	[0.04-0.068] unit decrease	0.054	EFO_0004713
ENSG00000055163	rs11738611	5	157345966	?	Menarche (age at onset)	30595370			EFO_0004703
ENSG00000055163	rs3087968	5	157395188	?	Lung function (FEV1/FVC)	30595370			EFO_0004713

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000055163's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000055163	CYFIP2	100	93.694	ENSG00000273749	CYFIP1	100	92.053	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000340	RNA 7-methylguanosine cap binding	21873635.	IBA	Function
GO:0000902	cell morphogenesis	21873635.	IBA	Process
GO:0005515	protein binding	11438699.15048733.24658146.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	11438699.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006915	apoptotic process	21873635.	IBA	Process
GO:0006915	apoptotic process	10449408.	IDA	Process
GO:0007411	axon guidance	21873635.	IBA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0030031	cell projection assembly	21873635.	IBA	Process
GO:0030054	cell junction	-	IEA	Component
GO:0031209	SCAR complex	21873635.	IBA	Component
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	-	TAS	Process
GO:0043005	neuron projection	21873635.	IBA	Component
GO:0045202	synapse	21873635.	IBA	Component
GO:0045202	synapse	11438699.	IDA	Component
GO:0045862	positive regulation of proteolysis	18387192.	IDA	Process
GO:0048010	vascular endothelial growth factor receptor signaling pathway	-	TAS	Process
GO:0048471	perinuclear region of cytoplasm	10449408.	IDA	Component
GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	-	IEA	Process
GO:0070062	extracellular exosome	19056867.20458337.23533145.	HDA	Component
GO:0097202	activation of cysteine-type endopeptidase activity	21873635.	IBA	Process
GO:0097202	activation of cysteine-type endopeptidase activity	18387192.	IDA	Process
GO:0097484	dendrite extension	-	IEA	Process
GO:0098609	cell-cell adhesion	15048733.	IDA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.