EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28241827	MicroRNA-30d promotes angiogenesis and tumor growth via MYPT1/c-JUN/VEGFA pathway and predicts aggressive outcome in prostate cancer.	Mol Cancer	2017 Feb 27	Lin ZY	doi: 10.1186/s12943-017-0615-x.
18079119	Green tea polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa laminin receptor.	J Biol Chem	2008 Feb 8	Umeda D	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr12	79934965	Intron	novel		0.47
BLCA	chr12	79809940	Missense_Mutation	novel	R437M	0.44
BLCA	chr12	79872926	Missense_Mutation	NA	D84H	0.11
BLCA	chr12	79806295	Missense_Mutation	NA	S565C	0.16
BLCA	chr12	79806319	Missense_Mutation	novel	R557K	0.2
BLCA	chr12	79808570	Missense_Mutation	NA	D488G	0.23
BLCA	chr12	79805622	Missense_Mutation	novel	S657F	0.31
BRCA	chr12	79774599	3'UTR	novel		0.38
BRCA	chr12	79935175	Intron	novel		0.25
BRCA	chr12	79935002	Intron	novel		0.6
BRCA	chr12	79775116	3'UTR	novel		0.42
BRCA	chr12	79797208	Missense_Mutation	NA	R760K	0.11
BRCA	chr12	79872819	Silent	NA	L119L	0.29
BRCA	chr12	79775829	3'UTR	novel		0.22
BRCA	chr12	79806204	Missense_Mutation	novel	K595N	0.14
BRCA	chr12	79797276	Frame_Shift_Del	novel	*K737Rfs13**	0.09
BRCA	chr12	79820816	Missense_Mutation	NA	E358K	0.11
BRCA	chr12	79793892	Nonsense_Mutation	NA	E874*	0.31
BRCA	chr12	79805708	Silent	rs761972298	T628T	0.28
BRCA	chr12	79797351	Silent	novel	G712G	0.08
BRCA	chr12	79820927	Missense_Mutation	NA	E321Q	0.25
BRCA	chr12	79821152	Frame_Shift_Del	NA	*K294Nfs8**	0.18
BRCA	chr12	79796894	Silent	novel	S783S	0.04
CESC	chr12	79820893	Missense_Mutation	NA	S332F	0.12
CESC	chr12	79795740	Silent	novel	E827E	0.21
CESC	chr12	79798504	Missense_Mutation	NA	R694T	0.29
CESC	chr12	79805592	Missense_Mutation	novel	R667I	0.47
CESC	chr12	79872863	Missense_Mutation	NA	E105K	0.21
CESC	chr12	79797344	Missense_Mutation	NA	R715C	0.45
CESC	chr12	79935116	Intron	novel		0.46
CESC	chr12	79775667	3'UTR	novel		0.57
CESC	chr12	79832399	Missense_Mutation	novel	R194W	0.28
CESC	chr12	79797254	Missense_Mutation	NA	E745Q	0.24
CESC	chr12	79795669	Missense_Mutation	novel	R851K	0.04
CHOL	chr12	79775667	3'UTR	novel		0.41
COAD	chr12	79934965	Intron	novel		0.44
COAD	chr12	79798536	Silent	NA	K683K	0.18
COAD	chr12	79796824	Missense_Mutation	novel	T807P	0.28
COAD	chr12	79832388	Missense_Mutation	NA	K197N	0.28
COAD	chr12	79934859	Missense_Mutation	novel	E25K	0.5
COAD	chr12	79934965	Intron	novel		0.23
COAD	chr12	79934726	Missense_Mutation	NA	A69V	0.27
COAD	chr12	79934936	5'UTR	novel		0.41
COAD	chr12	79786424	Missense_Mutation	novel	T953A	0.4
COAD	chr12	79797389	Missense_Mutation	NA	T700S	0.27
COAD	chr12	79807262	Frame_Shift_Del	rs776166170	*N540Ifs23**	0.49
COAD	chr12	79809922	Missense_Mutation	rs751773876	T443M	0.22
COAD	chr12	79775918	3'UTR	novel		0.73
COAD	chr12	79934740	Silent	novel	A64A	0.33
ESCA	chr12	79788582	Intron	novel		0.37
ESCA	chr12	79807313	Missense_Mutation	rs202164787	R523Q	0.74
ESCA	chr12	79788678	Silent	novel	L924L	0.09
GBM	chr12	79820922	Silent	novel	T322T	0.33
GBM	chr12	79934798	Missense_Mutation	novel	L45Q	0.19
GBM	chr12	79797372	Silent	NA	Q705Q	0.45
HNSC	chr12	79788779	Missense_Mutation	novel	E891K	0.29
HNSC	chr12	79832456	Missense_Mutation	novel	R175W	0.15
HNSC	chr12	79809942	Missense_Mutation	novel	W436C	0.45
HNSC	chr12	79809912	Silent	novel	Y446Y	0.68
HNSC	chr12	79845350	Missense_Mutation	novel	E147Q	0.28
HNSC	chr12	79817462	Missense_Mutation	rs551709799	A391T	0.21
KIRC	chr12	79788690	Nonsense_Mutation	novel	Y920*	0.21
KIRP	chr12	79809989	Missense_Mutation	NA	I421L	0.32
KIRP	chr12	79820824	Missense_Mutation	novel	C355Y	0.25
KIRP	chr12	79788771	Silent	novel	S893S	0.38
LGG	chr12	79806204	Missense_Mutation	novel	K595N	0.09
LGG	chr12	79807267	Missense_Mutation	novel	K538N	0.25
LIHC	chr12	79934965	Intron	novel		0.36
LIHC	chr12	79788634	Intron	novel		0.27
LIHC	chr12	79805769	Splice_Site	NA	X608_splice	0.18
LIHC	chr12	79934822	Missense_Mutation	novel	K37R	0.38
LUAD	chr12	79821108	Missense_Mutation	NA	D309G	0.22
LUAD	chr12	79828423	Missense_Mutation	novel	Y230C	0.25
LUAD	chr12	79796823	Missense_Mutation	rs761550105	T807I	0.26
LUAD	chr12	79820841	Missense_Mutation	novel	K349N	0.12
LUAD	chr12	79805707	Missense_Mutation	novel	A629S	0.67
LUAD	chr12	79805708	Silent	rs761972298	T628T	0.65
LUAD	chr12	79795664	Missense_Mutation	NA	T853A	0.5
LUSC	chr12	79796943	Missense_Mutation	novel	Q767R	0.08
LUSC	chr12	79809855	Silent	NA	A465A	0.28
LUSC	chr12	79788735	Silent	novel	L905L	0.12
LUSC	chr12	79805622	Missense_Mutation	novel	S657F	0.24
LUSC	chr12	79788599	Intron	novel		0.37
LUSC	chr12	79796803	Missense_Mutation	novel	I814L	0.11
LUSC	chr12	79788664	Missense_Mutation	novel	S929L	0.17
MESO	chr12	79808562	Missense_Mutation	novel	G491R	0.38
OV	chr12	79775799	3'UTR	novel		0.11
OV	chr12	79805655	Missense_Mutation	NA	T646R	0.31
OV	chr12	79797300	Missense_Mutation	novel	K729N	0.05
OV	chr12	79822156	Missense_Mutation	NA	I276T	0.48
OV	chr12	79845352	Missense_Mutation	NA	A146V	0.05
OV	chr12	79786426	Missense_Mutation	novel	D952V	0.09
OV	chr12	79775710	3'UTR	novel		0.56
OV	chr12	79806325	Missense_Mutation	novel	F555C	0.06
PRAD	chr12	79788743	Missense_Mutation	novel	S903A	0.39
READ	chr12	79790482	Missense_Mutation	rs764281068	T884M	0.41
READ	chr12	79820827	Missense_Mutation	NA	S354I	0.14
SARC	chr12	79805748	Missense_Mutation	NA	A615V	0.29
SARC	chr12	79775172	3'UTR	novel		0.21
SARC	chr12	79806174	Silent	rs374310208	T605T	0.26
SKCM	chr12	79809955	Missense_Mutation	NA	S432F	0.3
SKCM	chr12	79872827	Nonsense_Mutation	NA	G117*	0.09
SKCM	chr12	79809819	Silent	NA	S477S	0.34
SKCM	chr12	79788731	Missense_Mutation	NA	R907C	0.23
SKCM	chr12	79845308	Missense_Mutation	NA	R161W	0.48
SKCM	chr12	79808523	Silent	novel	R504R	0.25
SKCM	chr12	79872858	Silent	NA	G106G	0.23
SKCM	chr12	79832447	Missense_Mutation	rs766758074	L178F	0.39
STAD	chr12	79820787	Silent	NA	S367S	0.23
STAD	chr12	79820900	Missense_Mutation	NA	N330H	0.3
STAD	chr12	79809826	Missense_Mutation	novel	R475K	0.16
STAD	chr12	79796810	Silent	NA	S811S	0.26
STAD	chr12	79788594	Intron	novel		0.4
STAD	chr12	79793916	Missense_Mutation	novel	E866K	0.27
STAD	chr12	79817486	Missense_Mutation	NA	A383T	0.13
UCEC	chr12	79935042	Intron	novel		0.44
UCEC	chr12	79820881	Missense_Mutation	NA	S336Y	0.3
UCEC	chr12	79820809	Missense_Mutation	novel	D360V	0.31
UCEC	chr12	79786400	Missense_Mutation	novel	K961E	0.38
UCEC	chr12	79821108	Missense_Mutation	NA	D309G	0.25
UCEC	chr12	79934972	Intron	novel		0.07
UCEC	chr12	79778654	Intron	novel		0.21
UCEC	chr12	79774535	3'UTR	novel		0.32
UCEC	chr12	79820789	Missense_Mutation	novel	S367A	0.39
UCEC	chr12	79872860	Missense_Mutation	novel	G106S	0.43
UCEC	chr12	79795747	Frame_Shift_Ins	novel	*R825Kfs10**	0.44
UCEC	chr12	79821152	Frame_Shift_Del	NA	*K294Nfs8**	0.28
UCEC	chr12	79807262	Frame_Shift_Del	rs776166170	*N540Ifs23**	0.43
UCEC	chr12	79872937	Missense_Mutation	novel	A80D	0.43
UCEC	chr12	79845353	Missense_Mutation	novel	A146S	0.18
UCEC	chr12	79788485	Intron	novel		0.5
UCEC	chr12	79775962	Silent	novel	A1020A	0.5
UCEC	chr12	79788613	Intron	novel		0.39
UCEC	chr12	79797359	Missense_Mutation	novel	T710A	0.41
UCEC	chr12	79806330	Nonsense_Mutation	novel	C553*	0.38
UCEC	chr12	79774370	3'UTR	novel		0.26
UCEC	chr12	79778608	Splice_Region	novel		0.21
UCEC	chr12	79774822	3'UTR	novel		0.35
UCEC	chr12	79805706	Missense_Mutation	novel	A629V	0.43
UCEC	chr12	79822151	Frame_Shift_Ins	novel	*G278Wfs15**	0.04
UCEC	chr12	79822153	Nonsense_Mutation	novel	L277*	0.04
UCEC	chr12	79778771	Intron	novel		0.06
UCEC	chr12	79774706	3'UTR	novel		0.29
UCEC	chr12	79775667	3'UTR	novel		0.55
UCEC	chr12	79778733	Intron	novel		0.33
UCEC	chr12	79817407	Missense_Mutation	NA	S409L	0.16
UCEC	chr12	79775172	3'UTR	novel		0.5
UCEC	chr12	79934965	Intron	novel		0.4
UCEC	chr12	79820794	Missense_Mutation	rs370507874	S365L	0.22
UCEC	chr12	79774714	3'UTR	novel		0.47
UCEC	chr12	79797205	Missense_Mutation	NA	T761M	0.37
UCEC	chr12	79934965	Intron	novel		0.47
UCEC	chr12	79809978	Silent	NA	K424K	0.38
UCEC	chr12	79822157	Missense_Mutation	rs771702951	I276V	0.41
UCEC	chr12	79934869	Missense_Mutation	novel	E21D	0.17
UCEC	chr12	79774621	3'UTR	rs111954607		0.45
UCEC	chr12	79775667	3'UTR	novel		0.5
UCEC	chr12	79832360	Missense_Mutation	NA	A207S	0.35
UCEC	chr12	79774793	3'UTR	novel		0.44
UCEC	chr12	79775337	3'UTR	novel		0.46
UCEC	chr12	79788652	Missense_Mutation	novel	K933R	0.32
UCEC	chr12	79788769	Missense_Mutation	novel	S894Y	0.41
UCEC	chr12	79775752	3'UTR	novel		0.56
UCEC	chr12	79807262	Frame_Shift_Del	rs776166170	*N540Ifs23**	0.4
UCEC	chr12	79935006	Intron	novel		0.9
UCEC	chr12	79797205	Missense_Mutation	NA	T761M	0.38
UCEC	chr12	79934965	Intron	novel		0.44
UCEC	chr12	79796876	Missense_Mutation	NA	S789R	0.46
UCEC	chr12	79775726	3'UTR	novel		0.36
UCEC	chr12	79832470	Missense_Mutation	NA	R170Q	0.37
UCEC	chr12	79805767	Missense_Mutation	novel	T609A	0.38
UCEC	chr12	79822145	Silent	novel	L280L	0.33
UCEC	chr12	79775393	3'UTR	novel		0.3
UCEC	chr12	79845417	Missense_Mutation	novel	F124L	0.16
UCEC	chr12	79774599	3'UTR	novel		0.36
UCEC	chr12	79775172	3'UTR	novel		0.31
UCEC	chr12	79935006	Intron	novel		0.53
UCEC	chr12	79845343	Missense_Mutation	novel	E149G	0.25
UCEC	chr12	79795694	Nonsense_Mutation	novel	R843*	0.2
UCEC	chr12	79821089	Missense_Mutation	novel	K315N	0.24
UCEC	chr12	79778608	Splice_Region	novel		0.3
UCEC	chr12	79788569	Intron	novel		0.44
UCEC	chr12	79935024	Intron	novel		0.44
UCEC	chr12	79828403	Missense_Mutation	novel	H237N	0.05
UCEC	chr12	79774526	3'UTR	novel		0.13
UCEC	chr12	79806287	Missense_Mutation	novel	P568S	0.33
UCEC	chr12	79774612	3'UTR	novel		0.26
UCEC	chr12	79775788	3'UTR	novel		0.64
UCEC	chr12	79934965	Intron	novel		0.12
UCEC	chr12	79774543	3'UTR	novel		0.25
UCEC	chr12	79934965	Intron	novel		0.39
UCEC	chr12	79778636	Intron	novel		0.37
UCEC	chr12	79775172	3'UTR	novel		0.42
UCEC	chr12	79935200	Intron	novel		0.37
UCEC	chr12	79807261	Frame_Shift_Ins	NA	*N540Kfs2**	0.42
UCEC	chr12	79832430	Missense_Mutation	NA	Q183H	0.28
UCEC	chr12	79809940	Frame_Shift_Ins	novel	*R437Tfs9**	0.05
UCEC	chr12	79807272	Missense_Mutation	novel	L537F	0.24
UCEC	chr12	79808575	Missense_Mutation	novel	E486D	0.23
UCEC	chr12	79806305	Missense_Mutation	novel	L562V	0.39
UCEC	chr12	79778649	Intron	novel		0.54
UCEC	chr12	79828412	Missense_Mutation	novel	T234A	0.3
UCEC	chr12	79788695	Missense_Mutation	novel	P919S	0.1

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.0111	0.20414
ESCA	DEL	0.1793	0.045584
HNSC	DEL	0.067	0.22646
LUAD	DEL	0.1415	0.0059643
PAAD	DEL	0.1848	0.0030251
PRAD	AMP	0.0569	0.016187
READ	DEL	0.103	0.064633
SKCM	DEL	0.1717	0.00079981

Survival Analysis

Cancer	P-value	Q-value
THYM	0.041	Kaplan-Meier Survival Analysis
KIRC	0.016	Kaplan-Meier Survival Analysis
STAD	0.036	Kaplan-Meier Survival Analysis
SKCM	0.00011	Kaplan-Meier Survival Analysis
KIRP	0.013	Kaplan-Meier Survival Analysis
PCPG	0.044	Kaplan-Meier Survival Analysis
KICH	0.017	Kaplan-Meier Survival Analysis
GBM	0.036	Kaplan-Meier Survival Analysis
LIHC	0.00045	Kaplan-Meier Survival Analysis
LGG	0.0047	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000058272 (Gene tree)
Gene ID: 4659
Gene Symbol: PPP1R12A
Alias: MBS|M130|MYPT1
Full Name: protein phosphatase 1 regulatory subunit 12A
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 161,898 bases
Position: chr12:79,773,563-79,935,460
Accession: 7618
RBP type: non-canonical RBP
Summary: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
14736875	TIA proteins are necessary but not sufficient for the tissue-specific splicing of the myosin phosphatase targeting subunit 1.	J Biol Chem	2004 Apr 2	Shukla S	-
26864628	Two distinct myosin II populations coordinate ovulatory contraction of the myoepithelial sheath in the Caenorhabditis elegans somatic gonad.	Mol Biol Cell	2016 Apr 1	Ono K	doi: 10.1091/mbc.E15-09-0648

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000548318	PPP1R12A-209	582	-	ENSP00000449843	97 (aa)	-	F8VW28
ENST00000261207	PPP1R12A-201	5582	-	ENSP00000261207	1030 (aa)	-	O14974
ENST00000650220	PPP1R12A-223	1143	-	ENSP00000497229	381 (aa)	-	-
ENST00000551781	PPP1R12A-219	629	-	-	- (aa)	-	-
ENST00000547131	PPP1R12A-206	897	-	ENSP00000450061	299 (aa)	-	H0YIS4
ENST00000546369	PPP1R12A-204	2977	-	ENSP00000449514	943 (aa)	-	O14974
ENST00000550351	PPP1R12A-215	738	-	-	- (aa)	-	-
ENST00000550510	PPP1R12A-216	631	-	ENSP00000447338	210 (aa)	-	H0YHL8
ENST00000550001	PPP1R12A-211	631	-	-	- (aa)	-	-
ENST00000548908	PPP1R12A-210	3064	-	-	- (aa)	-	-
ENST00000551191	PPP1R12A-218	602	-	-	- (aa)	-	-
ENST00000550007	PPP1R12A-212	443	-	-	- (aa)	-	-
ENST00000437004	PPP1R12A-202	4639	XM_017019330	ENSP00000416769	995 (aa)	XP_016874819	O14974
ENST00000546762	PPP1R12A-205	1257	-	ENSP00000450059	234 (aa)	-	H0YIS3
ENST00000550903	PPP1R12A-217	959	-	ENSP00000449647	161 (aa)	-	H0YIL7
ENST00000553081	PPP1R12A-221	1101	-	ENSP00000447144	367 (aa)	-	H0YHI8
ENST00000450142	PPP1R12A-203	5721	XM_005268887	ENSP00000389168	1030 (aa)	XP_005268944	O14974
ENST00000550107	PPP1R12A-213	2925	XM_011538379	ENSP00000446855	974 (aa)	XP_011536681	O14974
ENST00000634739	PPP1R12A-222	560	-	ENSP00000489242	100 (aa)	-	A0A0U1RQZ1
ENST00000547330	PPP1R12A-208	2275	-	ENSP00000446816	692 (aa)	-	F8VZN8
ENST00000547253	PPP1R12A-207	676	-	-	- (aa)	-	-
ENST00000550299	PPP1R12A-214	683	-	ENSP00000449666	188 (aa)	-	H0YIM2
ENST00000552892	PPP1R12A-220	2277	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000058272's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04022	cGMP-PKG signaling pathway	KEGG
hsa04024	cAMP signaling pathway	KEGG
hsa04270	Vascular smooth muscle contraction	KEGG
hsa04510	Focal adhesion	KEGG
hsa04611	Platelet activation	KEGG
hsa04810	Regulation of actin cytoskeleton	KEGG
hsa04921	Oxytocin signaling pathway	KEGG
hsa05205	Proteoglycans in cancer	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000058272	Body Weights and Measures	7.11998451862422E-7	17903300
ENSG00000058272	Body Weights and Measures	2.96344358470478E-7	17903300
ENSG00000058272	Platelet Function Tests	4.8990600E-005	-
ENSG00000058272	Platelet Function Tests	5.4178880E-014	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000058272	rs113146373	12	79784781	?	Velopharyngeal dysfunction	29855589	[NR] unit decrease	0.1339413	EFO_0009336

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000058272's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000058272	PPP1R12A	100	98.148	ENSMUSG00000019907	Ppp1r12a	100	92.435	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000086	G2/M transition of mitotic cell cycle	-	TAS	Process
GO:0000278	mitotic cell cycle	18477460.	IMP	Process
GO:0000776	kinetochore	18477460.	IDA	Component
GO:0004857	enzyme inhibitor activity	21873635.	IBA	Function
GO:0004857	enzyme inhibitor activity	19245366.	IDA	Function
GO:0005515	protein binding	11067852.15292222.16417406.18073109.20195357.25609649.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005813	centrosome	18477460.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0006470	protein dephosphorylation	18477460.	IMP	Process
GO:0007098	centrosome cycle	18477460.	IMP	Process
GO:0007165	signal transduction	-	IEA	Process
GO:0015629	actin cytoskeleton	-	IDA	Component
GO:0019208	phosphatase regulator activity	21873635.	IBA	Function
GO:0019208	phosphatase regulator activity	20354225.	IDA	Function
GO:0019208	phosphatase regulator activity	18477460.	IMP	Function
GO:0019901	protein kinase binding	18477460.	IPI	Function
GO:0030018	Z disc	21873635.	IBA	Component
GO:0030018	Z disc	-	ISS	Component
GO:0030155	regulation of cell adhesion	20354225.	IDA	Process
GO:0031672	A band	21873635.	IBA	Component
GO:0031672	A band	-	ISS	Component
GO:0035507	regulation of myosin-light-chain-phosphatase activity	20354225.	IDA	Process
GO:0035508	positive regulation of myosin-light-chain-phosphatase activity	21873635.	IBA	Process
GO:0035508	positive regulation of myosin-light-chain-phosphatase activity	25816133.	IMP	Process
GO:0035690	cellular response to drug	-	IEA	Process
GO:0043086	negative regulation of catalytic activity	19245366.	IDA	Process
GO:0043292	contractile fiber	20634291.	IDA	Component
GO:0045944	positive regulation of transcription by RNA polymerase II	19245366.	IDA	Process
GO:0046822	regulation of nucleocytoplasmic transport	-	IEA	Process
GO:0071889	14-3-3 protein binding	20354225.	IDA	Function
GO:0072357	PTW/PP1 phosphatase complex	20354225.	IDA	Component
GO:1903140	regulation of establishment of endothelial barrier	25816133.	IMP	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.