EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr5	128158151	Missense_Mutation	NA	G821D	0.5
BLCA	chr5	128148771	Silent	NA	N633N	0.08
BLCA	chr5	128148870	Missense_Mutation	novel	I666M	0.07
BLCA	chr5	128152733	Missense_Mutation	novel	A764V	0.09
BLCA	chr5	128084467	Silent	novel	F171F	0.34
BLCA	chr5	128131148	Missense_Mutation	novel	A377D	0.12
BLCA	chr5	128138599	Missense_Mutation	novel	E471K	0.17
BLCA	chr5	128150043	Silent	novel	A684A	0.05
BLCA	chr5	128151323	Silent	novel	I730I	0.14
BLCA	chr5	128141975	Frame_Shift_Ins	novel	*F590Kfs13**	0.08
BLCA	chr5	128150034	Silent	novel	F681F	0.57
BLCA	chr5	128171729	Missense_Mutation	novel	S929C	0.06
BRCA	chr5	128171682	Missense_Mutation	rs111986207	I913M	0.41
BRCA	chr5	128174658	Missense_Mutation	novel	T974I	0.09
BRCA	chr5	128186647	3'UTR	novel		0.26
BRCA	chr5	128158043	Intron	novel		0.09
BRCA	chr5	128147696	Missense_Mutation	novel	L616F	0.11
BRCA	chr5	128187719	3'UTR	novel		0.38
BRCA	chr5	128138649	Missense_Mutation	rs772305204	F487L	0.14
BRCA	chr5	128138880	Missense_Mutation	novel	L531F	0.18
BRCA	chr5	128138881	Missense_Mutation	NA	V532I	0.18
BRCA	chr5	128114618	Missense_Mutation	novel	V329I	0.09
BRCA	chr5	128131088	Missense_Mutation	novel	S357F	0.3
BRCA	chr5	128174550	Missense_Mutation	NA	L938S	0.52
CESC	chr5	128187462	3'UTR	novel		1
CESC	chr5	128186512	Nonsense_Mutation	NA	R1174*	0.26
CESC	chr5	128187762	3'UTR	novel		0.22
CESC	chr5	128171734	Missense_Mutation	NA	L931V	0.14
CESC	chr5	128131147	Missense_Mutation	NA	A377T	0.4
CESC	chr5	128141962	Missense_Mutation	novel	G585D	0.42
CESC	chr5	128171716	Missense_Mutation	novel	G925C	0.36
CESC	chr5	128182933	Missense_Mutation	novel	K1097N	0.16
CESC	chr5	128187120	3'UTR	novel		0.4
CESC	chr5	128158063	Missense_Mutation	NA	L792F	0.14
COAD	chr5	128151306	Missense_Mutation	NA	I725V	0.42
COAD	chr5	128184417	Frame_Shift_Ins	NA	*E1119Rfs7**	0.47
COAD	chr5	128114288	Splice_Site	novel	X318_splice	0.24
COAD	chr5	128112905	Missense_Mutation	novel	V283A	0.2
COAD	chr5	128180914	Silent	rs371244344	T1044T	0.22
COAD	chr5	128135697	Splice_Region	rs369058298		0.22
COAD	chr5	128148781	Missense_Mutation	novel	A637T	0.04
COAD	chr5	128112879	Silent	NA	T274T	0.22
COAD	chr5	128180948	Missense_Mutation	NA	V1056I	0.28
COAD	chr5	128084383	Missense_Mutation	novel	F143L	0.38
COAD	chr5	128180995	Splice_Site	NA	X1071_splice	0.08
COAD	chr5	128135793	Frame_Shift_Del	novel	*F466Lfs59**	0.11
COAD	chr5	128184762	Intron	novel		0.69
COAD	chr5	128184831	Missense_Mutation	NA	S1160P	0.39
COAD	chr5	128114663	Missense_Mutation	novel	N344H	0.13
COAD	chr5	128134189	Nonsense_Mutation	NA	E405*	0.18
COAD	chr5	128141865	Missense_Mutation	NA	N553D	0.1
COAD	chr5	128180948	Missense_Mutation	NA	V1056L	0.13
COAD	chr5	128134205	Missense_Mutation	rs537215758	R410Q	0.27
COAD	chr5	128158166	Splice_Site	novel	X825_splice	0.06
COAD	chr5	128174543	Nonsense_Mutation	NA	E936*	0.16
COAD	chr5	128182937	Nonsense_Mutation	NA	E1099*	0.05
COAD	chr5	128186498	Frame_Shift_Ins	NA	*P1171Sfs18**	0.38
COAD	chr5	128184474	Silent	NA	D1136D	0.17
COAD	chr5	128167777	Missense_Mutation	NA	R878H	0.21
ESCA	chr5	128151386	Frame_Shift_Ins	novel	*P754Tfs35**	0.19
ESCA	chr5	128178636	Missense_Mutation	novel	Q1016L	0.7
ESCA	chr5	128167876	Intron	novel		0.29
GBM	chr5	128186635	3'UTR	novel		0.09
GBM	chr5	128184380	Missense_Mutation	NA	E1105G	0.36
GBM	chr5	128131140	Missense_Mutation	novel	F374L	0.16
GBM	chr5	128138639	Missense_Mutation	novel	E484A	0.11
GBM	chr5	128174617	Silent	rs780180222	S960S	0.16
GBM	chr5	128114612	Missense_Mutation	novel	A327T	0.39
GBM	chr5	128084426	Missense_Mutation	NA	D158H	0.46
GBM	chr5	128114676	Missense_Mutation	novel	R348I	0.29
GBM	chr5	128178652	Missense_Mutation	rs747879416	K1021N	0.35
GBM	chr5	128184464	Missense_Mutation	rs771030042	R1133Q	0.58
HNSC	chr5	128167886	Intron	novel		0.19
HNSC	chr5	128174654	In_Frame_Del	novel	I973del	0.29
HNSC	chr5	128171737	Nonsense_Mutation	novel	Q932*	0.13
HNSC	chr5	128180920	Frame_Shift_Ins	novel	*W1049Mfs5**	0.2
HNSC	chr5	128152769	Missense_Mutation	NA	R776L	0.38
KIRC	chr5	128161667	Missense_Mutation	rs372863815	R828Q	0.31
KIRC	chr5	128148779	Missense_Mutation	NA	P636L	0.17
KIRC	chr5	128131112	Missense_Mutation	NA	G365V	0.16
KIRC	chr5	128161794	Missense_Mutation	NA	L870F	0.09
KIRC	chr5	128152807	Splice_Site	NA	X788_splice	0.23
KIRC	chr5	128151246	Missense_Mutation	NA	R705C	0.12
KIRC	chr5	128186566	In_Frame_Ins	novel	D1193_L1194insQD	0.3
LAML	chr5	128131114	Missense_Mutation	novel	G366S	0.09
LAML	chr5	128158108	Missense_Mutation	novel	L807F	0.05
LGG	chr5	128167766	Silent	rs1132905	A874A	0.34
LGG	chr5	128180900	Missense_Mutation	novel	P1040S	0.32
LGG	chr5	128186748	3'UTR	novel		0.28
LGG	chr5	128114260	Missense_Mutation	NA	S309P	0.29
LIHC	chr5	128148815	Missense_Mutation	NA	N648S	0.13
LIHC	chr5	128131141	Missense_Mutation	NA	A375S	0.39
LIHC	chr5	128177146	Frame_Shift_Del	novel	*E993Nfs9**	0.42
LIHC	chr5	128147662	Missense_Mutation	novel	A605G	0.31
LIHC	chr5	128186717	3'UTR	novel		0.15
LIHC	chr5	128184390	Silent	novel	I1108I	0.17
LIHC	chr5	128186639	3'UTR	novel		0.34
LIHC	chr5	128184733	Intron	novel		0.03
LIHC	chr5	128147687	Silent	novel	S613S	0.3
LUAD	chr5	128131182	Silent	NA	A388A	0.2
LUAD	chr5	128167776	Missense_Mutation	rs772690122	R878C	0.14
LUAD	chr5	128151344	Silent	NA	L737L	0.22
LUAD	chr5	128114265	Missense_Mutation	NA	W310C	0.33
LUAD	chr5	128186676	3'UTR	novel		0.17
LUAD	chr5	128161762	Missense_Mutation	novel	A860T	0.19
LUAD	chr5	128152735	Missense_Mutation	rs548545596	L765V	0.39
LUAD	chr5	128151334	Missense_Mutation	novel	A734G	0.28
LUAD	chr5	128152726	Missense_Mutation	NA	T762S	0.16
LUAD	chr5	128147715	Missense_Mutation	NA	P623S	0.13
LUAD	chr5	128131207	Splice_Site	novel	X396_splice	0.39
LUAD	chr5	128180989	Silent	novel	R1069R	0.28
LUAD	chr5	128135807	Splice_Region	novel	K469K	0.25
LUAD	chr5	128178624	Missense_Mutation	novel	S1012I	0.48
LUAD	chr5	128174622	Nonsense_Mutation	novel	L962*	0.16
LUAD	chr5	128151386	Frame_Shift_Ins	novel	*P754Tfs35**	0.14
LUAD	chr5	128177127	Silent	NA	T984T	0.15
LUAD	chr5	128134261	Nonsense_Mutation	NA	E429*	0.31
LUAD	chr5	128171740	Missense_Mutation	NA	G933R	0.21
LUAD	chr5	128147728	Missense_Mutation	novel	Q627R	0.28
LUAD	chr5	128167928	Intron	novel		0.75
LUAD	chr5	128141874	Missense_Mutation	novel	I556F	0.3
LUAD	chr5	128141876	Frame_Shift_Del	novel	*V557Nfs13**	0.28
LUAD	chr5	128180936	Missense_Mutation	NA	C1052S	0.3
LUSC	chr5	128184476	Missense_Mutation	novel	N1137I	0.56
LUSC	chr5	128112816	Splice_Region	novel	E253E	0.13
LUSC	chr5	128182879	Silent	novel	F1079F	0.18
LUSC	chr5	128182880	Missense_Mutation	novel	R1080W	0.18
LUSC	chr5	128178668	In_Frame_Ins	novel	W1027delinsFCSNLSCR	0.2
LUSC	chr5	128180896	Missense_Mutation	novel	L1038F	0.6
LUSC	chr5	128167955	Intron	novel		0.42
LUSC	chr5	128084647	Silent	NA	A231A	0.19
LUSC	chr5	128112903	Silent	novel	V282V	0.28
LUSC	chr5	128112841	Missense_Mutation	NA	G262R	0.41
LUSC	chr5	128180989	Silent	novel	R1069R	0.75
LUSC	chr5	128134194	Missense_Mutation	NA	I406M	0.23
LUSC	chr5	128184426	Silent	NA	Q1120Q	0.11
LUSC	chr5	128151318	Missense_Mutation	rs575733487	V729I	0.43
LUSC	chr5	128084383	Missense_Mutation	NA	F143L	0.65
LUSC	chr5	128112838	Missense_Mutation	novel	N261D	0.62
LUSC	chr5	128178663	Missense_Mutation	novel	D1025A	0.25
OV	chr5	128131085	Missense_Mutation	novel	I356K	0.12
OV	chr5	128148841	Missense_Mutation	NA	L657V	0.1
OV	chr5	128167776	Missense_Mutation	rs772690122	R878C	0.48
OV	chr5	128151275	Missense_Mutation	NA	W714C	0.73
PAAD	chr5	128151334	Missense_Mutation	novel	A734G	0.15
PAAD	chr5	128161710	Silent	novel	Y842Y	0.18
PAAD	chr5	128152769	Missense_Mutation	rs373411636	R776H	0.24
PRAD	chr5	128180913	Missense_Mutation	rs375675214	T1044M	0.37
READ	chr5	128112908	Missense_Mutation	novel	K284T	0.38
READ	chr5	128134205	Missense_Mutation	rs537215758	R410Q	0.37
READ	chr5	128138910	Splice_Site	novel	X541_splice	0.39
READ	chr5	128158072	Missense_Mutation	NA	T795A	0.35
READ	chr5	128151373	Missense_Mutation	novel	I747N	0.49
READ	chr5	128151374	Silent	novel	I747I	0.49
SARC	chr5	128187914	3'UTR	novel		0.52
SARC	chr5	128184795	Missense_Mutation	novel	R1148W	0.25
SKCM	chr5	128084353	Silent	novel	E133E	0.38
SKCM	chr5	128084354	Missense_Mutation	novel	E134K	0.33
SKCM	chr5	128167899	Intron	novel		0.29
SKCM	chr5	128138632	Nonsense_Mutation	rs747216802	R482*	0.15
SKCM	chr5	128148829	Missense_Mutation	rs763260162	R653C	0.27
SKCM	chr5	128186738	3'UTR	novel		0.43
SKCM	chr5	128174618	Missense_Mutation	rs753799701	D961N	0.32
SKCM	chr5	128180944	Silent	NA	I1054I	0.35
SKCM	chr5	128135747	Silent	rs377735249	F449F	0.21
SKCM	chr5	128112921	Silent	rs139820355	I288I	0.23
SKCM	chr5	128138599	Missense_Mutation	novel	E471K	0.45
SKCM	chr5	128141876	Silent	rs111727169	I556I	0.1
SKCM	chr5	128186655	3'UTR	novel		0.93
SKCM	chr5	128134227	Silent	novel	V417V	0.25
SKCM	chr5	128112880	Missense_Mutation	NA	Y275H	0.24
SKCM	chr5	128138674	Missense_Mutation	novel	P496S	0.22
SKCM	chr5	128158122	Silent	novel	F811F	0.27
STAD	chr5	128084534	Frame_Shift_Del	novel	*H195Tfs89**	0.21
STAD	chr5	128184378	Silent	novel	F1104F	0.06
STAD	chr5	128184792	Missense_Mutation	rs116065946	Y1147H	0.11
STAD	chr5	128112853	Missense_Mutation	NA	T266A	0.26
STAD	chr5	128147635	Missense_Mutation	NA	V596A	0.07
STAD	chr5	128174618	Missense_Mutation	NA	D961Y	0.39
STAD	chr5	128186620	Missense_Mutation	NA	F1210V	0.3
STAD	chr5	128151311	Silent	NA	V726V	0.2
UCEC	chr5	128158047	Splice_Region	novel		0.31
UCEC	chr5	128161667	Missense_Mutation	rs372863815	R828Q	0.27
UCEC	chr5	128182933	Silent	NA	K1097K	0.2
UCEC	chr5	128186695	3'UTR	novel		0.38
UCEC	chr5	128112847	Nonsense_Mutation	novel	E264*	0.07
UCEC	chr5	128157996	Intron	novel		0.2
UCEC	chr5	128189070	3'UTR	novel		0.33
UCEC	chr5	128161667	Missense_Mutation	rs372863815	R828Q	0.41
UCEC	chr5	128182937	Nonsense_Mutation	NA	E1099*	0.27
UCEC	chr5	128161696	Missense_Mutation	rs746611648	D838N	0.38
UCEC	chr5	128147634	Missense_Mutation	novel	V596M	0.33
UCEC	chr5	128186618	Missense_Mutation	novel	T1209I	0.05
UCEC	chr5	128187981	3'UTR	rs187398964		0.54
UCEC	chr5	128151297	Missense_Mutation	novel	L722I	0.03
UCEC	chr5	128148772	Missense_Mutation	rs771531911	I634V	0.49
UCEC	chr5	128184463	Nonsense_Mutation	rs747023237	R1133*	0.41
UCEC	chr5	128147673	Missense_Mutation	novel	S609P	0.37
UCEC	chr5	128186651	3'UTR	novel		0.44
UCEC	chr5	128186807	3'UTR	rs547509906		0.11
UCEC	chr5	128189591	3'UTR	novel		0.27
UCEC	chr5	128186593	Missense_Mutation	novel	R1201C	0.3
UCEC	chr5	128167827	Missense_Mutation	NA	A895T	0.26
UCEC	chr5	128180894	Missense_Mutation	novel	L1038V	0.05
UCEC	chr5	128138632	Nonsense_Mutation	rs747216802	R482*	0.4
UCEC	chr5	128084433	Missense_Mutation	novel	A160V	0.16
UCEC	chr5	128167961	Intron	novel		0.21
UCEC	chr5	128131135	Missense_Mutation	novel	A373T	0.18
UCEC	chr5	128168053	Intron	novel		0.44
UCEC	chr5	128178575	Missense_Mutation	NA	G996C	0.13
UCEC	chr5	128112879	Silent	rs771221035	T274T	0.6
UCEC	chr5	128158067	Missense_Mutation	novel	V793A	0.21
UCEC	chr5	128171704	Missense_Mutation	rs778158149	R921C	0.19
UCEC	chr5	128114617	Silent	novel	T328T	0.31
UCEC	chr5	128141904	Missense_Mutation	novel	A566T	0.31
UCEC	chr5	128152805	Missense_Mutation	novel	R788K	0.32
UCEC	chr5	128188625	3'UTR	novel		0.33
UCEC	chr5	128171705	Missense_Mutation	rs371689331	R921H	0.33
UCEC	chr5	128114216	Missense_Mutation	novel	R294H	0.42
UCEC	chr5	128151245	Nonsense_Mutation	novel	W704*	0.38
UCEC	chr5	128178637	Frame_Shift_Ins	novel	*Q1019Tfs7**	0.52
UCEC	chr5	128187620	3'UTR	novel		0.15
UCEC	chr5	128189507	3'UTR	novel		0.67
UCEC	chr5	128134205	Missense_Mutation	rs537215758	R410Q	0.46
UCEC	chr5	128167985	Intron	novel		0.43
UCEC	chr5	128186724	3'UTR	rs747967143		0.54
UCEC	chr5	128186639	3'UTR	rs777663327		0.16
UCEC	chr5	128186805	3'UTR	novel		0.17
UCEC	chr5	128186806	3'UTR	novel		0.17
UCEC	chr5	128161715	Missense_Mutation	rs144463493	R844Q	0.17
UCEC	chr5	128184380	Missense_Mutation	novel	E1105V	0.17
UCEC	chr5	128187792	3'UTR	novel		0.42
UCEC	chr5	128152769	Missense_Mutation	rs373411636	R776H	0.47
UCEC	chr5	128141862	Missense_Mutation	rs770560514	V552I	0.36
UCEC	chr5	128112880	Missense_Mutation	NA	Y275H	0.29
UCEC	chr5	128187983	3'UTR	rs371727295		0.25
UCEC	chr5	128184463	Nonsense_Mutation	rs747023237	R1133*	0.45
UCEC	chr5	128178637	Silent	NA	Q1016Q	0.03
UCEC	chr5	128186720	3'UTR	novel		0.08
UCEC	chr5	128189615	3'UTR	novel		0.42
UCEC	chr5	128178568	Missense_Mutation	NA	E993D	0.41
UCEC	chr5	128182869	Missense_Mutation	novel	L1076P	0.35
UCEC	chr5	128148862	Missense_Mutation	NA	G664R	0.28
UCEC	chr5	128150009	Missense_Mutation	NA	V673A	0.34
UCEC	chr5	128167882	Intron	novel		0.28
UCEC	chr5	128186806	3'UTR	novel		0.28
UCEC	chr5	128150090	Nonsense_Mutation	novel	*K700Nfs3**	0.08
UCEC	chr5	128151247	Missense_Mutation	NA	R705H	0.29
UCEC	chr5	128174610	Missense_Mutation	NA	K958I	0.3
UCEC	chr5	128184421	Nonsense_Mutation	NA	E1119*	0.25
UCEC	chr5	128158026	Intron	novel		0.32
UCEC	chr5	128141943	Missense_Mutation	novel	S579R	0.09
UCEC	chr5	128180914	Silent	rs371244344	T1044T	0.53
UCEC	chr5	128184464	Missense_Mutation	rs771030042	R1133Q	0.5
UCEC	chr5	128152794	Silent	novel	V784V	0.43
UCEC	chr5	128158091	Missense_Mutation	rs142105778	R801H	0.4
UCEC	chr5	128188822	3'UTR	novel		0.38
UCEC	chr5	128150093	Missense_Mutation	NA	S701Y	0.22
UCEC	chr5	128151247	Missense_Mutation	NA	R705H	0.27
UCEC	chr5	128161788	Missense_Mutation	NA	Q868H	0.31
UCEC	chr5	128134163	Splice_Site	novel	X397_splice	0.42
UCEC	chr5	128134228	Missense_Mutation	rs768407146	V418M	0.41
UCEC	chr5	128167805	Silent	novel	G887G	0.06
UCEC	chr5	128186909	3'UTR	NA		0.23
UCEC	chr5	128187651	3'UTR	novel		0.36
UCEC	chr5	128135747	Silent	rs377735249	F449F	0.41
UCEC	chr5	128131069	Nonsense_Mutation	novel	G351*	0.32
UCEC	chr5	128147629	Missense_Mutation	novel	S594I	0.5
UCEC	chr5	128150015	Missense_Mutation	novel	A675V	0.35

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	DEL	0.0382	0.11554
LAML	DEL	0.0838	1.2971e-07
LUAD	DEL	0.2946	7.4776e-05
LUSC	DEL	0.6527	0.002071
MESO	DEL	0.1724	0.20184
PRAD	AMP	0.0285	0.16448
STAD	DEL	0.2766	2.8835e-08
THCA	AMP	0.0361	0.075436
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.0046	Kaplan-Meier Survival Analysis
ACC	0.04	Kaplan-Meier Survival Analysis
UCS	0.0083	Kaplan-Meier Survival Analysis
HNSC	0.012	Kaplan-Meier Survival Analysis
COAD	0.016	Kaplan-Meier Survival Analysis
PAAD	0.025	Kaplan-Meier Survival Analysis
BLCA	0.0088	Kaplan-Meier Survival Analysis
READ	0.0023	Kaplan-Meier Survival Analysis
LAML	0.00015	Kaplan-Meier Survival Analysis
UCEC	0.0015	Kaplan-Meier Survival Analysis
LIHC	0.0024	Kaplan-Meier Survival Analysis
LGG	0.012	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000064651 (Gene tree)
Gene ID: 6558
Gene Symbol: SLC12A2
Alias: NKCC1|BSC|BSC2|PPP1R141
Full Name: solute carrier family 12 member 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 105,923 bases
Position: chr5:128,083,766-128,189,688
Accession: 10911
RBP type: non-canonical RBP
Summary: The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000509616	SLC12A2-207	580	-	-	- (aa)	-	-
ENST00000504416	SLC12A2-204	3653	-	-	- (aa)	-	-
ENST00000343225	SLC12A2-202	5509	-	ENSP00000340878	1196 (aa)	-	P55011
ENST00000509205	SLC12A2-206	4263	-	ENSP00000427109	1150 (aa)	-	G3XAL9
ENST00000262461	SLC12A2-201	6885	XM_017009771	ENSP00000262461	1212 (aa)	XP_016865260	P55011
ENST00000502849	SLC12A2-203	489	-	-	- (aa)	-	-
ENST00000628403	SLC12A2-208	3617	-	ENSP00000486323	1150 (aa)	-	G3XAL9
ENST00000507791	SLC12A2-205	555	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000064651's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04970	Salivary secretion	KEGG
hsa04972	Pancreatic secretion	KEGG
hsa05110	Vibrio cholerae infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000064651	Body Weights and Measures	5.20889768949391E-6	17903300
ENSG00000064651	Body Weights and Measures	4.32118025117837E-6	17903300
ENSG00000064651	Body Weights and Measures	4.32051119738854E-6	17903300
ENSG00000064651	Body Weights and Measures	3.64322895623924E-6	17903300
ENSG00000064651	Stroke	8.3589458E-004	-
ENSG00000064651	Carcinoid Tumor	2E-6	21139019

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000064651	rs10089	5	128186851	?	Ileal carcinoids	21139019	[1.79-3.70]	2.56	EFO_0004243
ENSG00000064651	rs7734927	5	128118043	A	Red cell distribution width	28957414	[0.1-0.12] unit increase	0.112536	EFO_0005192
ENSG00000064651	rs3101725	5	128188326	C	Varicose veins	30566020	[0.11-0.18] unit decrease	0.143	HP_0002619
ENSG00000064651	rs185689480	5	128186065	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000064651	rs2568928	5	128151911	?	Eosinophil counts	30595370			EFO_0004842
ENSG00000064651	rs2568928	5	128151911	?	Heel bone mineral density	30595370			EFO_0009270
ENSG00000064651	rs1112956	5	128098106	G	Breast cancer	29059683	[0.018-0.047] unit decrease	0.0328	EFO_0000305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000064651's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	17721439.22570591.24555568.	IPI	Function
GO:0005886	plasma membrane	-	TAS	Component
GO:0005887	integral component of plasma membrane	7629105.	TAS	Component
GO:0006811	ion transport	-	TAS	Process
GO:0006884	cell volume homeostasis	21873635.	IBA	Process
GO:0006972	hyperosmotic response	-	IEA	Process
GO:0007214	gamma-aminobutyric acid signaling pathway	-	IEA	Process
GO:0007568	aging	-	IEA	Process
GO:0008511	sodium:potassium:chloride symporter activity	21873635.	IBA	Function
GO:0008519	ammonium transmembrane transporter activity	21873635.	IBA	Function
GO:0008519	ammonium transmembrane transporter activity	12946942.18032481.	IDA	Function
GO:0010818	T cell chemotaxis	27400149.	IMP	Process
GO:0015081	sodium ion transmembrane transporter activity	21873635.	IBA	Function
GO:0015378	sodium:chloride symporter activity	21873635.	IBA	Function
GO:0015379	potassium:chloride symporter activity	21873635.	IBA	Function
GO:0015696	ammonium transport	21873635.	IBA	Process
GO:0015696	ammonium transport	12946942.18032481.	IDA	Process
GO:0016020	membrane	7629105.	TAS	Component
GO:0016324	apical plasma membrane	21873635.	IBA	Component
GO:0019901	protein kinase binding	12740379.16669787.	IPI	Function
GO:0030321	transepithelial chloride transport	12946942.	IDA	Process
GO:0035725	sodium ion transmembrane transport	21873635.	IBA	Process
GO:0045795	positive regulation of cell volume	-	IEA	Process
GO:0055064	chloride ion homeostasis	21873635.	IBA	Process
GO:0055075	potassium ion homeostasis	21873635.	IBA	Process
GO:0055078	sodium ion homeostasis	21873635.	IBA	Process
GO:0070062	extracellular exosome	19199708.20458337.	HDA	Component
GO:0070634	transepithelial ammonium transport	18032481.	IDA	Process
GO:0072488	ammonium transmembrane transport	-	IEA	Process
GO:1902476	chloride transmembrane transport	21873635.	IBA	Process
GO:1903561	extracellular vesicle	24769233.	HDA	Component
GO:1990573	potassium ion import across plasma membrane	21873635.	IBA	Process
GO:1990869	cellular response to chemokine	27400149.	IMP	Process

EuRBPDB

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Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

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