EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
20578902	WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.	Thyroid	2010 Jul	Akdi A	doi: 10.1089/thy.2010.0072.
23049746	Possible role of the WDR3 gene on genome stability in thyroid cancer patients.	PLoS One	2012	Garc??a-Quispes WA	doi: 10.1371/journal.pone.0044288
20392698	Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation.	J Biol Chem	2010 Jun 11	McMahon M	doi: 10.1074/jbc.M110.108555

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	117955356	Splice_Region	rs145648133	S817S	0.26
BLCA	chr1	117933314	5'UTR	novel		0.35
BLCA	chr1	117959408	Missense_Mutation	NA	K931N	0.27
BLCA	chr1	117950000	Missense_Mutation	rs776121352	S539C	0.16
BLCA	chr1	117959402	Missense_Mutation	novel	K929N	0.42
BLCA	chr1	117934515	Missense_Mutation	novel	C72R	0.48
BLCA	chr1	117953535	Silent	NA	V754V	0.31
BLCA	chr1	117954064	Missense_Mutation	NA	E776K	0.35
BLCA	chr1	117950084	Missense_Mutation	novel	S567C	0.3
BLCA	chr1	117943567	Silent	novel	F423F	0.39
BLCA	chr1	117942501	Nonsense_Mutation	novel	E352*	0.05
BLCA	chr1	117959343	Missense_Mutation	rs768211246	E910K	0.29
BLCA	chr1	117957078	Missense_Mutation	novel	E822Q	0.21	Utp12
BLCA	chr1	117934586	Silent	novel	L95L	0.07
BRCA	chr1	117942492	Missense_Mutation	NA	L349V	0.38
BRCA	chr1	117952586	Missense_Mutation	NA	S692L	0.37
BRCA	chr1	117950065	Missense_Mutation	NA	Q561E	0.11
BRCA	chr1	117959596	3'UTR	novel		0.21
BRCA	chr1	117948444	Missense_Mutation	NA	L488M	0.4
BRCA	chr1	117952002	Silent	rs140893583	S610S	0.15
CESC	chr1	117939542	Silent	NA	L215L	0.2
CESC	chr1	117948410	Silent	NA	G476G	0.28
CESC	chr1	117948484	Missense_Mutation	novel	S501F	0.24
CESC	chr1	117934485	Nonsense_Mutation	novel	Q62*	0.44
CESC	chr1	117943470	Missense_Mutation	NA	L391S	0.39
CESC	chr1	117941176	Missense_Mutation	NA	R281T	0.4
COAD	chr1	117943439	Missense_Mutation	novel	V381F	0.05
COAD	chr1	117957135	Missense_Mutation	rs751941966	E841K	0.36	Utp12
COAD	chr1	117957135	Missense_Mutation	rs751941966	E841K	0.21	Utp12
COAD	chr1	117959363	Frame_Shift_Ins	novel	*A919Cfs2**	0.38
COAD	chr1	117943511	Missense_Mutation	NA	R405G	0.29
COAD	chr1	117957173	Silent	novel	C853C	0.34
COAD	chr1	117958984	Missense_Mutation	novel	S886L	0.11	Utp12
COAD	chr1	117936863	Missense_Mutation	rs139865932	R159Q	0.42
COAD	chr1	117933384	Missense_Mutation	novel	Q22L	0.07
COAD	chr1	117959342	Silent	rs147355005	C909C	0.1
COAD	chr1	117948489	Missense_Mutation	rs766730419	S503P	0.34
COAD	chr1	117949814	Missense_Mutation	NA	D530Y	0.39
COAD	chr1	117954041	Missense_Mutation	rs772217516	R768Q	0.27
COAD	chr1	117939505	Frame_Shift_Del	novel	*K204Sfs12**	0.29
COAD	chr1	117959353	Missense_Mutation	rs137952009	S913N	0.3
COAD	chr1	117934672	Missense_Mutation	NA	S124F	0.36
COAD	chr1	117941160	Missense_Mutation	rs150881258	R276W	0.17
COAD	chr1	117943526	Frame_Shift_Ins	novel	*T410Ifs46**	0.05
COAD	chr1	117943589	Missense_Mutation	NA	L431V	0.37
ESCA	chr1	117957185	Missense_Mutation	novel	F857L	0.07	Utp12
ESCA	chr1	117959555	3'UTR	novel		0.33
ESCA	chr1	117958965	In_Frame_Ins	novel	L880delinsCCYKDTCTRI	0.19	Utp12
GBM	chr1	117940842	Nonsense_Mutation	novel	E231*	0.18
HNSC	chr1	117955325	Missense_Mutation	novel	Y807F	0.9	Utp12
HNSC	chr1	117941214	Missense_Mutation	novel	L294V	0.1
HNSC	chr1	117954629	Splice_Site	novel	X803_splice	0.18
HNSC	chr1	117941782	Missense_Mutation	NA	I308M	0.15
HNSC	chr1	117933386	Missense_Mutation	novel	K23E	0.26
HNSC	chr1	117938487	Missense_Mutation	novel	D170N	0.28
HNSC	chr1	117953497	Missense_Mutation	novel	D742Y	0.2
KIRC	chr1	117933313	5'UTR	novel		0.39
KIRC	chr1	117940921	Missense_Mutation	rs142439174	T257M	0.37
KIRP	chr1	117933285	Splice_Region	novel		0.33
KIRP	chr1	117959401	Missense_Mutation	rs763008067	K929R	0.35
LAML	chr1	117941162	Silent	novel	R276R	0.1
LGG	chr1	117946119	Silent	novel	C454C	0.38
LGG	chr1	117958952	Silent	novel	P875P	0.42
LGG	chr1	117941160	Missense_Mutation	rs150881258	R276W	0.16
LIHC	chr1	117957109	Missense_Mutation	novel	V832A	0.04	Utp12
LUAD	chr1	117950032	Missense_Mutation	novel	E550K	0.28
LUAD	chr1	117952527	Splice_Site	novel	X673_splice	0.4
LUAD	chr1	117936774	Silent	novel	T129T	0.14
LUAD	chr1	117942473	Missense_Mutation	novel	E342D	0.11
LUAD	chr1	117936817	Missense_Mutation	rs762504967	R144C	0.26
LUAD	chr1	117941804	Missense_Mutation	NA	K316E	0.45
LUAD	chr1	117936824	Missense_Mutation	novel	K146M	0.34
LUAD	chr1	117950026	Missense_Mutation	novel	L548I	0.08
LUAD	chr1	117934675	Missense_Mutation	NA	G125V	0.1
LUAD	chr1	117952616	Frame_Shift_Del	novel	*E703Rfs52**	0.16
LUAD	chr1	117958910	Missense_Mutation	NA	R861S	0.15	Utp12
LUSC	chr1	117948496	Missense_Mutation	novel	S505Y	0.19
LUSC	chr1	117934610	Missense_Mutation	novel	F103L	0.19
LUSC	chr1	117950082	Silent	novel	V566V	0.16
LUSC	chr1	117954613	Missense_Mutation	NA	Y799N	0.17
LUSC	chr1	117950116	Missense_Mutation	rs760784329	V578I	0.33
LUSC	chr1	117940875	Missense_Mutation	NA	P242S	0.33
LUSC	chr1	117940876	Missense_Mutation	NA	P242L	0.32
LUSC	chr1	117959001	Missense_Mutation	novel	R892G	0.13	Utp12
LUSC	chr1	117948459	Missense_Mutation	NA	D493Y	0.11
OV	chr1	117941813	Missense_Mutation	NA	D319N	0.19
OV	chr1	117952306	Nonsense_Mutation	novel	Y638*	0.04
OV	chr1	117959402	Frame_Shift_Del	novel	*R930Gfs9**	0.09
OV	chr1	117950015	Missense_Mutation	rs145257054	R544Q	0.37
OV	chr1	117940934	Silent	novel	P261P	0.04
PAAD	chr1	117949774	Silent	rs111307478	A516A	0.21
PAAD	chr1	117952590	Silent	rs139563237	S693S	0.22
PAAD	chr1	117958909	Splice_Site	novel	X861_splice	0.08
PAAD	chr1	117934640	Missense_Mutation	novel	L113F	0.06
PAAD	chr1	117942492	Frame_Shift_Del	novel	*L349Cfs8**	0.42
PRAD	chr1	117936795	Silent	NA	V136V	0.49
PRAD	chr1	117943441	Silent	novel	V381V	0.15
PRAD	chr1	117941789	Missense_Mutation	novel	K311E	0.33
READ	chr1	117940858	Missense_Mutation	novel	K236T	0.04
SARC	chr1	117941126	Splice_Region	novel	R264R	0.29
SARC	chr1	117957134	Silent	rs764543878	N840N	0.3
SKCM	chr1	117938495	Missense_Mutation	NA	M172I	0.12
SKCM	chr1	117952661	Missense_Mutation	rs773830110	M717T	0.28
SKCM	chr1	117952359	Missense_Mutation	NA	K656R	0.08
SKCM	chr1	117933413	Missense_Mutation	NA	R32C	0.28
SKCM	chr1	117955346	Missense_Mutation	novel	G814E	0.22	Utp12
SKCM	chr1	117955347	Silent	novel	G814G	0.22
SKCM	chr1	117943510	Silent	NA	V404V	0.33
SKCM	chr1	117934606	Missense_Mutation	novel	T102I	0.42
SKCM	chr1	117952367	Nonsense_Mutation	NA	Q659*	0.08
SKCM	chr1	117936841	Missense_Mutation	NA	I152F	0.39
SKCM	chr1	117943484	Missense_Mutation	NA	P396S	0.28
SKCM	chr1	117941134	Missense_Mutation	NA	S267L	0.53
SKCM	chr1	117941799	Missense_Mutation	novel	I314N	0.16
SKCM	chr1	117957188	Silent	NA	F858F	0.15
SKCM	chr1	117957140	Silent	NA	F842F	0.19
SKCM	chr1	117943459	Silent	NA	N387N	0.32
SKCM	chr1	117958918	Missense_Mutation	novel	F864C	0.2	Utp12
SKCM	chr1	117959384	Silent	novel	S923S	0.33
STAD	chr1	117957114	Missense_Mutation	novel	D834N	0.05	Utp12
STAD	chr1	117940845	Missense_Mutation	NA	P232S	0.05
STAD	chr1	117943553	Missense_Mutation	NA	R419W	0.04
STAD	chr1	117957135	Missense_Mutation	rs751941966	E841K	0.42	Utp12
STAD	chr1	117946098	Missense_Mutation	NA	Q447H	0.38
STAD	chr1	117949825	Missense_Mutation	NA	S533R	0.18
STAD	chr1	117938490	Missense_Mutation	NA	T171A	0.23
STAD	chr1	117933345	Missense_Mutation	NA	R9H	0.11
THCA	chr1	117941800	Frame_Shift_Del	novel	*Q315Efs5**	0.07
THYM	chr1	117941124	Nonsense_Mutation	rs781395374	R264*	0.23
UCEC	chr1	117933457	Silent	novel	H46H	0.22
UCEC	chr1	117953539	Missense_Mutation	NA	A756S	0.29
UCEC	chr1	117952643	Missense_Mutation	novel	L711P	0.09
UCEC	chr1	117933429	Missense_Mutation	rs200209712	R37H	0.33
UCEC	chr1	117934535	Silent	NA	L78L	0.37
UCEC	chr1	117936862	Nonsense_Mutation	rs370011105	R159*	0.05
UCEC	chr1	117959414	Missense_Mutation	NA	K933N	0.37
UCEC	chr1	117943626	Missense_Mutation	novel	R443K	0.33
UCEC	chr1	117952372	Nonsense_Mutation	novel	W660*	0.06
UCEC	chr1	117959459	3'UTR	novel		0.23
UCEC	chr1	117934631	Silent	NA	I110I	0.41
UCEC	chr1	117941848	Splice_Site	novel	X330_splice	0.38
UCEC	chr1	117946151	Missense_Mutation	novel	G465V	0.43
UCEC	chr1	117959460	3'UTR	novel		0.44
UCEC	chr1	117943542	Missense_Mutation	rs138214784	R415H	0.17
UCEC	chr1	117952642	Missense_Mutation	novel	L711F	0.14
UCEC	chr1	117938551	Missense_Mutation	rs774316410	R191Q	0.39
UCEC	chr1	117950070	Silent	NA	K562K	0.47
UCEC	chr1	117952630	Missense_Mutation	NA	E707K	0.35
UCEC	chr1	117939476	Splice_Site	NA	X194_splice	0.36
UCEC	chr1	117952012	Missense_Mutation	novel	N614D	0.47
UCEC	chr1	117957136	Missense_Mutation	novel	E841A	0.38	Utp12
UCEC	chr1	117943492	Silent	NA	L398L	0.29
UCEC	chr1	117946138	Missense_Mutation	novel	F461L	0.2
UCEC	chr1	117959497	3'UTR	novel		0.5
UCEC	chr1	117948462	Missense_Mutation	novel	A494T	0.25
UCEC	chr1	117934511	Nonsense_Mutation	novel	C70*	0.35
UCEC	chr1	117952318	Silent	novel	V642V	0.05
UCEC	chr1	117934570	Missense_Mutation	novel	R90Q	0.64
UCEC	chr1	117950075	Missense_Mutation	novel	L564S	0.37
UCEC	chr1	117934668	Missense_Mutation	novel	A123T	0.32
UCEC	chr1	117952359	Missense_Mutation	novel	K656T	0.36
UCEC	chr1	117949773	Missense_Mutation	novel	A516V	0.35
UCEC	chr1	117957135	Missense_Mutation	rs751941966	E841K	0.2	Utp12
UCEC	chr1	117954603	Missense_Mutation	NA	I795M	0.54
UCEC	chr1	117933371	Missense_Mutation	rs751061868	V18I	0.35
UCEC	chr1	117950003	Missense_Mutation	novel	V540A	0.42
UCEC	chr1	117950015	Missense_Mutation	rs145257054	R544Q	0.08
UCEC	chr1	117943542	Missense_Mutation	rs138214784	R415H	0.05
UCEC	chr1	117939558	Missense_Mutation	novel	A221S	0.13
UCEC	chr1	117957114	Missense_Mutation	novel	D834Y	0.15	Utp12
UCEC	chr1	117933305	5'UTR	novel		0.32
UCEC	chr1	117934568	Silent	NA	I89I	0.38
UCEC	chr1	117952303	Missense_Mutation	NA	M637I	0.18
UCEC	chr1	117938491	Missense_Mutation	novel	T171I	0.32
UCEC	chr1	117933453	Missense_Mutation	NA	E45G	0.2
UCEC	chr1	117952952	Nonsense_Mutation	NA	E720*	0.36
UCEC	chr1	117938491	Missense_Mutation	novel	T171I	0.18
UCEC	chr1	117949756	Silent	novel	G510G	0.33
UCEC	chr1	117952052	Missense_Mutation	novel	K627R	0.3
UCEC	chr1	117958949	Silent	novel	V874V	0.25
UCEC	chr1	117941126	Splice_Region	novel	R264R	0.45
UCEC	chr1	117946099	Missense_Mutation	novel	C448R	0.27
UCEC	chr1	117939544	Missense_Mutation	NA	R216M	0.26
UCEC	chr1	117948494	Silent	novel	L504L	0.53

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0915	0.01281
COAD	DEL	0.2018	0.00038973
DLBC	DEL	0.125	0.0017831
HNSC	DEL	0.1973	7.836e-19
LUAD	DEL	0.2229	2.5961e-13
LUSC	DEL	0.3553	1.8628e-17
READ	DEL	0.2485	0.013822
SKCM	DEL	0.1553	9.7877e-07
STAD	DEL	0.1565	0.0040659
TGCT	AMP	0.22	0.088103
UVM	DEL	0.2375	0.061261

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00072	Kaplan-Meier Survival Analysis
SARC	0.00027	Kaplan-Meier Survival Analysis
ACC	0.0025	Kaplan-Meier Survival Analysis
HNSC	0.018	Kaplan-Meier Survival Analysis
SKCM	0.027	Kaplan-Meier Survival Analysis
PRAD	0.04	Kaplan-Meier Survival Analysis
LUSC	0.038	Kaplan-Meier Survival Analysis
KIRP	0.0029	Kaplan-Meier Survival Analysis
PAAD	0.00065	Kaplan-Meier Survival Analysis
CESC	0.013	Kaplan-Meier Survival Analysis
READ	0.00087	Kaplan-Meier Survival Analysis
KICH	0.009	Kaplan-Meier Survival Analysis
UCEC	0.0013	Kaplan-Meier Survival Analysis
GBM	0.014	Kaplan-Meier Survival Analysis
LIHC	0.0066	Kaplan-Meier Survival Analysis
LGG	0.0014	Kaplan-Meier Survival Analysis
LUAD	0.007	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000065183 (Gene tree)
Gene ID: 10885
Gene Symbol: WDR3
Alias: FLJ12796|UTP12|DIP2
Full Name: WD repeat domain 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 36,823 bases
Position: chr1:117,929,720-117,966,542
Accession: 12755
RBP type: canonical RBP
Summary: This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000308179	Utp12	PF04003.12	3.6e-21	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000487202	WDR3-204	680	-	-	- (aa)	-	-
ENST00000349139	WDR3-201	9974	-	ENSP00000308179	943 (aa)	-	Q9UNX4
ENST00000471680	WDR3-203	732	-	-	- (aa)	-	-
ENST00000369441	WDR3-202	1035	-	ENSP00000358449	40 (aa)	-	Q6PDA5

Gene Model

Click here to download ENSG00000065183's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000065183	Adiponectin	2.96057820372653E-6	17903298
ENSG00000065183	Cholesterol, HDL	7.43226604730706E-6	17903299

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000065183's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000065183	WDR3	98	67.714	ENSAPOG00000005975	wdr3	99	70.694	Acanthochromis_polyacanthus
ENSG00000065183	WDR3	100	94.592	ENSAMEG00000004339	WDR3	100	94.592	Ailuropoda_melanoleuca
ENSG00000065183	WDR3	99	55.438	ENSACIG00000006993	wdr3	99	59.408	Amphilophus_citrinellus
ENSG00000065183	WDR3	99	70.201	ENSAOCG00000023966	wdr3	99	70.917	Amphiprion_ocellaris
ENSG00000065183	WDR3	99	70.445	ENSAPEG00000018223	wdr3	99	70.445	Amphiprion_percula
ENSG00000065183	WDR3	99	70.339	ENSATEG00000000703	wdr3	99	70.339	Anabas_testudineus
ENSG00000065183	WDR3	100	74.973	ENSACAG00000008210	WDR3	99	75.159	Anolis_carolinensis
ENSG00000065183	WDR3	100	96.182	ENSANAG00000033348	WDR3	100	96.182	Aotus_nancymaae
ENSG00000065183	WDR3	98	70.671	ENSACLG00000016975	wdr3	99	70.551	Astatotilapia_calliptera
ENSG00000065183	WDR3	100	70.930	ENSAMXG00000005755	wdr3	100	70.930	Astyanax_mexicanus
ENSG00000065183	WDR3	100	94.486	ENSBTAG00000019937	WDR3	100	94.486	Bos_taurus
ENSG00000065183	WDR3	99	34.062	WBGene00017435	F13H8.2	97	34.045	Caenorhabditis_elegans
ENSG00000065183	WDR3	100	95.652	ENSCJAG00000005749	WDR3	100	95.652	Callithrix_jacchus
ENSG00000065183	WDR3	100	93.425	ENSCAFG00000009916	WDR3	100	93.425	Canis_familiaris
ENSG00000065183	WDR3	82	93.821	ENSCAFG00020020610	WDR3	99	94.127	Canis_lupus_dingo
ENSG00000065183	WDR3	100	94.168	ENSCHIG00000010490	WDR3	100	94.168	Capra_hircus
ENSG00000065183	WDR3	100	94.603	ENSTSYG00000002158	WDR3	100	94.603	Carlito_syrichta
ENSG00000065183	WDR3	100	74.047	ENSCAPG00000015805	WDR3	100	74.047	Cavia_aperea
ENSG00000065183	WDR3	100	93.531	ENSCPOG00000011305	WDR3	100	93.531	Cavia_porcellus
ENSG00000065183	WDR3	100	95.758	ENSCCAG00000037237	WDR3	100	95.758	Cebus_capucinus
ENSG00000065183	WDR3	100	98.621	ENSCATG00000037200	WDR3	100	98.621	Cercocebus_atys
ENSG00000065183	WDR3	100	93.637	ENSCLAG00000010657	WDR3	100	93.637	Chinchilla_lanigera
ENSG00000065183	WDR3	100	98.409	ENSCSAG00000001705	WDR3	100	98.409	Chlorocebus_sabaeus
ENSG00000065183	WDR3	83	94.286	ENSCHOG00000006428	WDR3	88	94.286	Choloepus_hoffmanni
ENSG00000065183	WDR3	99	82.590	ENSCPBG00000001426	WDR3	99	82.803	Chrysemys_picta_bellii
ENSG00000065183	WDR3	100	91.729	ENSCGRG00001019544	Wdr3	100	91.729	Cricetulus_griseus_chok1gshd
ENSG00000065183	WDR3	87	90.517	ENSCGRG00000001027	Wdr3	91	90.476	Cricetulus_griseus_crigri
ENSG00000065183	WDR3	99	68.955	ENSCSEG00000009381	wdr3	100	68.889	Cynoglossus_semilaevis
ENSG00000065183	WDR3	99	66.385	ENSCVAG00000014846	wdr3	99	66.173	Cyprinodon_variegatus
ENSG00000065183	WDR3	100	71.308	ENSDARG00000011079	wdr3	100	71.459	Danio_rerio
ENSG00000065183	WDR3	100	93.425	ENSDNOG00000018114	WDR3	100	93.425	Dasypus_novemcinctus
ENSG00000065183	WDR3	100	90.536	ENSDORG00000011031	Wdr3	100	91.062	Dipodomys_ordii
ENSG00000065183	WDR3	98	42.173	FBgn0038597	CG8064	98	42.173	Drosophila_melanogaster
ENSG00000065183	WDR3	100	94.380	ENSEASG00005006393	WDR3	100	94.380	Equus_asinus_asinus
ENSG00000065183	WDR3	100	94.698	ENSECAG00000006575	WDR3	99	94.698	Equus_caballus
ENSG00000065183	WDR3	95	92.152	ENSEEUG00000002218	WDR3	100	92.152	Erinaceus_europaeus
ENSG00000065183	WDR3	100	68.849	ENSELUG00000005997	wdr3	100	69.166	Esox_lucius
ENSG00000065183	WDR3	100	93.849	ENSFCAG00000003469	WDR3	100	93.849	Felis_catus
ENSG00000065183	WDR3	98	77.681	ENSFALG00000005089	WDR3	99	76.882	Ficedula_albicollis
ENSG00000065183	WDR3	100	93.001	ENSFDAG00000016284	WDR3	100	93.001	Fukomys_damarensis
ENSG00000065183	WDR3	99	68.565	ENSFHEG00000012138	wdr3	99	65.263	Fundulus_heteroclitus
ENSG00000065183	WDR3	92	64.126	ENSGMOG00000002962	wdr3	100	64.126	Gadus_morhua
ENSG00000065183	WDR3	100	79.958	ENSGALG00000014791	WDR3	99	80.042	Gallus_gallus
ENSG00000065183	WDR3	99	69.280	ENSGAFG00000013102	wdr3	99	69.345	Gambusia_affinis
ENSG00000065183	WDR3	95	63.720	ENSGACG00000008251	wdr3	100	63.720	Gasterosteus_aculeatus
ENSG00000065183	WDR3	98	80.173	ENSGAGG00000009171	WDR3	96	82.623	Gopherus_agassizii
ENSG00000065183	WDR3	100	99.682	ENSGGOG00000009982	WDR3	100	99.682	Gorilla_gorilla
ENSG00000065183	WDR3	98	70.779	ENSHBUG00000004367	wdr3	99	70.657	Haplochromis_burtoni
ENSG00000065183	WDR3	100	93.213	ENSHGLG00000017936	WDR3	100	93.213	Heterocephalus_glaber_female
ENSG00000065183	WDR3	100	93.213	ENSHGLG00100008292	WDR3	100	93.213	Heterocephalus_glaber_male
ENSG00000065183	WDR3	100	63.834	ENSHCOG00000017501	wdr3	98	68.591	Hippocampus_comes
ENSG00000065183	WDR3	100	70.190	ENSIPUG00000003396	wdr3	100	70.296	Ictalurus_punctatus
ENSG00000065183	WDR3	100	93.955	ENSSTOG00000003504	WDR3	100	93.955	Ictidomys_tridecemlineatus
ENSG00000065183	WDR3	100	90.678	ENSJJAG00000013861	Wdr3	100	90.678	Jaculus_jaculus
ENSG00000065183	WDR3	98	69.148	ENSKMAG00000016004	wdr3	99	70.279	Kryptolebias_marmoratus
ENSG00000065183	WDR3	99	66.702	ENSLBEG00000013757	wdr3	99	66.702	Labrus_bergylta
ENSG00000065183	WDR3	98	68.069	ENSLACG00000014259	WDR3	98	67.849	Latimeria_chalumnae
ENSG00000065183	WDR3	98	69.397	ENSLOCG00000011052	wdr3	100	69.336	Lepisosteus_oculatus
ENSG00000065183	WDR3	100	93.001	ENSLAFG00000012108	WDR3	100	93.001	Loxodonta_africana
ENSG00000065183	WDR3	100	98.515	ENSMFAG00000034570	WDR3	100	98.515	Macaca_fascicularis
ENSG00000065183	WDR3	100	98.409	ENSMMUG00000008513	WDR3	100	98.409	Macaca_mulatta
ENSG00000065183	WDR3	100	98.515	ENSMNEG00000039555	WDR3	100	98.515	Macaca_nemestrina
ENSG00000065183	WDR3	100	98.409	ENSMLEG00000035516	WDR3	100	98.409	Mandrillus_leucophaeus
ENSG00000065183	WDR3	99	67.762	ENSMAMG00000020737	wdr3	99	67.869	Mastacembelus_armatus
ENSG00000065183	WDR3	98	66.919	ENSMZEG00005019253	wdr3	99	66.455	Maylandia_zebra
ENSG00000065183	WDR3	99	78.159	ENSMGAG00000014241	WDR3	100	78.267	Meleagris_gallopavo
ENSG00000065183	WDR3	100	92.153	ENSMAUG00000002574	Wdr3	100	92.153	Mesocricetus_auratus
ENSG00000065183	WDR3	100	93.856	ENSMICG00000001783	WDR3	100	93.856	Microcebus_murinus
ENSG00000065183	WDR3	100	90.148	ENSMOCG00000014361	Wdr3	100	90.148	Microtus_ochrogaster
ENSG00000065183	WDR3	99	67.053	ENSMMOG00000019419	wdr3	99	67.053	Mola_mola
ENSG00000065183	WDR3	100	87.169	ENSMODG00000005243	WDR3	100	87.169	Monodelphis_domestica
ENSG00000065183	WDR3	100	62.963	ENSMALG00000016265	wdr3	100	62.646	Monopterus_albus
ENSG00000065183	WDR3	100	90.678	MGP_CAROLIEiJ_G0025421	Wdr3	100	90.678	Mus_caroli
ENSG00000065183	WDR3	100	90.890	ENSMUSG00000033285	Wdr3	100	90.890	Mus_musculus
ENSG00000065183	WDR3	100	91.208	MGP_PahariEiJ_G0026865	Wdr3	100	91.208	Mus_pahari
ENSG00000065183	WDR3	100	90.996	MGP_SPRETEiJ_G0026371	Wdr3	100	90.996	Mus_spretus
ENSG00000065183	WDR3	100	94.274	ENSMPUG00000001565	WDR3	100	94.274	Mustela_putorius_furo
ENSG00000065183	WDR3	100	94.062	ENSMLUG00000003500	WDR3	100	94.062	Myotis_lucifugus
ENSG00000065183	WDR3	100	92.789	ENSNGAG00000021117	Wdr3	100	92.789	Nannospalax_galili
ENSG00000065183	WDR3	98	63.135	ENSNBRG00000015140	wdr3	99	62.145	Neolamprologus_brichardi
ENSG00000065183	WDR3	100	98.834	ENSNLEG00000005304	WDR3	100	98.834	Nomascus_leucogenys
ENSG00000065183	WDR3	95	92.982	ENSMEUG00000009673	WDR3	81	92.982	Notamacropus_eugenii
ENSG00000065183	WDR3	100	83.704	ENSOPRG00000001857	WDR3	100	83.704	Ochotona_princeps
ENSG00000065183	WDR3	93	92.449	ENSODEG00000000136	WDR3	100	92.449	Octodon_degus
ENSG00000065183	WDR3	98	70.563	ENSONIG00000015678	wdr3	99	70.339	Oreochromis_niloticus
ENSG00000065183	WDR3	100	76.882	ENSOANG00000003070	WDR3	100	76.882	Ornithorhynchus_anatinus
ENSG00000065183	WDR3	100	95.228	ENSOCUG00000007572	WDR3	100	95.228	Oryctolagus_cuniculus
ENSG00000065183	WDR3	99	68.538	ENSORLG00020022391	wdr3	99	68.644	Oryzias_latipes_hni
ENSG00000065183	WDR3	99	68.326	ENSORLG00015023208	wdr3	99	68.432	Oryzias_latipes_hsok
ENSG00000065183	WDR3	99	68.750	ENSOMEG00000017592	wdr3	100	69.101	Oryzias_melastigma
ENSG00000065183	WDR3	100	94.698	ENSOGAG00000007399	WDR3	100	94.698	Otolemur_garnettii
ENSG00000065183	WDR3	100	93.757	ENSOARG00000020325	WDR3	100	93.757	Ovis_aries
ENSG00000065183	WDR3	100	99.470	ENSPPAG00000029068	WDR3	100	99.470	Pan_paniscus
ENSG00000065183	WDR3	100	93.955	ENSPPRG00000022972	WDR3	100	93.955	Panthera_pardus
ENSG00000065183	WDR3	100	93.955	ENSPTIG00000016747	WDR3	100	93.955	Panthera_tigris_altaica
ENSG00000065183	WDR3	100	99.470	ENSPTRG00000001168	WDR3	100	99.470	Pan_troglodytes
ENSG00000065183	WDR3	100	98.621	ENSPANG00000020680	WDR3	100	98.621	Papio_anubis
ENSG00000065183	WDR3	99	70.582	ENSPKIG00000024900	wdr3	99	70.582	Paramormyrops_kingsleyae
ENSG00000065183	WDR3	99	82.909	ENSPSIG00000017455	WDR3	99	82.909	Pelodiscus_sinensis
ENSG00000065183	WDR3	98	67.100	ENSPMGG00000022686	wdr3	99	66.234	Periophthalmus_magnuspinnatus
ENSG00000065183	WDR3	100	92.153	ENSPEMG00000011928	Wdr3	100	92.153	Peromyscus_maniculatus_bairdii
ENSG00000065183	WDR3	95	87.556	ENSPCIG00000000938	WDR3	99	87.556	Phascolarctos_cinereus
ENSG00000065183	WDR3	99	68.889	ENSPFOG00000017900	wdr3	99	69.060	Poecilia_formosa
ENSG00000065183	WDR3	99	69.174	ENSPLAG00000014362	wdr3	99	69.345	Poecilia_latipinna
ENSG00000065183	WDR3	100	99.046	ENSPPYG00000000970	WDR3	100	99.046	Pongo_abelii
ENSG00000065183	WDR3	92	78.547	ENSPCAG00000001265	WDR3	100	78.547	Procavia_capensis
ENSG00000065183	WDR3	98	67.243	ENSPNYG00000006217	wdr3	99	66.208	Pundamilia_nyererei
ENSG00000065183	WDR3	100	72.017	ENSPNAG00000006843	wdr3	100	72.017	Pygocentrus_nattereri
ENSG00000065183	WDR3	100	90.360	ENSRNOG00000019670	Wdr3	100	90.360	Rattus_norvegicus
ENSG00000065183	WDR3	99	97.652	ENSRBIG00000039149	WDR3	100	95.464	Rhinopithecus_bieti
ENSG00000065183	WDR3	100	98.197	ENSRROG00000028066	WDR3	100	98.197	Rhinopithecus_roxellana
ENSG00000065183	WDR3	99	37.336	YLR129W	DIP2	98	37.474	Saccharomyces_cerevisiae
ENSG00000065183	WDR3	100	95.970	ENSSBOG00000015569	WDR3	100	95.970	Saimiri_boliviensis_boliviensis
ENSG00000065183	WDR3	100	87.025	ENSSHAG00000005169	WDR3	100	87.025	Sarcophilus_harrisii
ENSG00000065183	WDR3	99	69.101	ENSSFOG00015000595	wdr3	99	68.995	Scleropages_formosus
ENSG00000065183	WDR3	99	68.427	ENSSMAG00000008334	wdr3	98	68.817	Scophthalmus_maximus
ENSG00000065183	WDR3	98	70.996	ENSSDUG00000014276	wdr3	99	70.869	Seriola_dumerili
ENSG00000065183	WDR3	98	69.838	ENSSLDG00000012837	wdr3	99	70.011	Seriola_lalandi_dorsalis
ENSG00000065183	WDR3	95	83.860	ENSSARG00000002347	WDR3	100	83.860	Sorex_araneus
ENSG00000065183	WDR3	99	73.595	ENSSPUG00000005582	WDR3	99	73.807	Sphenodon_punctatus
ENSG00000065183	WDR3	100	93.955	ENSSSCG00000006727	WDR3	100	93.955	Sus_scrofa
ENSG00000065183	WDR3	98	77.681	ENSTGUG00000013357	WDR3	99	77.306	Taeniopygia_guttata
ENSG00000065183	WDR3	99	68.114	ENSTRUG00000002727	wdr3	100	68.360	Takifugu_rubripes
ENSG00000065183	WDR3	98	67.171	ENSTNIG00000005299	wdr3	98	67.061	Tetraodon_nigroviridis
ENSG00000065183	WDR3	83	97.638	ENSTBEG00000002549	WDR3	74	97.638	Tupaia_belangeri
ENSG00000065183	WDR3	100	85.154	ENSTTRG00000003817	WDR3	100	85.154	Tursiops_truncatus
ENSG00000065183	WDR3	100	89.608	ENSUAMG00000023139	WDR3	100	89.608	Ursus_americanus
ENSG00000065183	WDR3	90	92.105	ENSVPAG00000000073	WDR3	89	92.105	Vicugna_pacos
ENSG00000065183	WDR3	100	93.637	ENSVVUG00000010629	WDR3	100	93.637	Vulpes_vulpes
ENSG00000065183	WDR3	98	73.491	ENSXETG00000009920	wdr3	99	73.523	Xenopus_tropicalis
ENSG00000065183	WDR3	99	69.068	ENSXMAG00000009827	wdr3	99	69.239	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0031965	nuclear membrane	-	IDA	Component
GO:0032040	small-subunit processome	21873635.	IBA	Component
GO:0034388	Pwp2p-containing subcomplex of 90S preribosome	21873635.	IBA	Component

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.