EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26297734	The Estrogen Receptor Cofactor SPEN Functions as a Tumor Suppressor and Candidate Biomarker of Drug Responsiveness in Hormone-Dependent Breast Cancers.	Cancer Res	2015 Oct 15	L??gar?? S	doi: 10.1158/0008-5472.CAN-14-3475
15824732	An essential role of Pak1 phosphorylation of SHARP in Notch signaling.	Oncogene	2005 Jun 30	Vadlamudi RK	-
20460484	Identification of a quantitative MINT locus methylation profile predicting local regional recurrence of rectal cancer.	Clin Cancer Res	2010 May 15	de Maat MF	doi: 10.1158/1078-0432.CCR-09-2717
28877752	SPEN, a new player in primary cilia formation and cell migration in breast cancer.	Breast Cancer Res	2017 Sep 6	L??gar?? S	doi: 10.1186/s13058-017-0897-3.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	15935248	Missense_Mutation	NA	S3003L	0.13
BLCA	chr1	15876629	Missense_Mutation	novel	S278A	0.34
BLCA	chr1	15935715	Missense_Mutation	novel	E3159K	0.3
BLCA	chr1	15934953	Missense_Mutation	NA	D2905N	0.49
BLCA	chr1	15938715	Splice_Region	novel		0.38
BLCA	chr1	15932120	Silent	rs139575390	A1960A	0.4
BLCA	chr1	15934331	Silent	NA	V2697V	0.11
BLCA	chr1	15933801	Missense_Mutation	NA	D2521N	0.25
BLCA	chr1	15936254	Silent	NA	K3338K	0.48
BLCA	chr1	15929622	Missense_Mutation	novel	D1128N	0.11
BLCA	chr1	15931443	Missense_Mutation	novel	P1735S	0.15
BLCA	chr1	15929003	Silent	novel	Q921Q	0.07
BLCA	chr1	15932529	Missense_Mutation	novel	D2097H	0.2
BLCA	chr1	15873115	Missense_Mutation	NA	R128H	0.34
BLCA	chr1	15920917	Silent	novel	E561E	0.08
BLCA	chr1	15933253	Missense_Mutation	novel	S2338L	0.58
BLCA	chr1	15876209	Missense_Mutation	novel	D138N	0.33
BLCA	chr1	15939571	3'UTR	novel		0.4
BLCA	chr1	15928150	Missense_Mutation	rs149954308	R637Q	0.47
BLCA	chr1	15939391	Silent	NA	I3653I	0.29
BLCA	chr1	15876491	Silent	novel	R232R	0.2
BLCA	chr1	15930133	Missense_Mutation	novel	S1298F	0.3
BLCA	chr1	15932058	Missense_Mutation	rs755331266	E1940K	0.21
BLCA	chr1	15929001	Nonsense_Mutation	novel	Q921*	0.25
BLCA	chr1	15932880	Missense_Mutation	novel	E2214Q	0.19
BLCA	chr1	15933628	Missense_Mutation	novel	S2463T	0.16
BLCA	chr1	15933842	Silent	novel	L2534L	0.23
BLCA	chr1	15932931	Missense_Mutation	novel	E2231Q	0.34
BLCA	chr1	15928508	Nonsense_Mutation	NA	Y756*	0.25
BLCA	chr1	15918923	Splice_Region	novel		0.34
BLCA	chr1	15935534	Silent	novel	V3098V	0.45
BLCA	chr1	15931796	Silent	novel	L1852L	0.1
BLCA	chr1	15934173	Missense_Mutation	novel	Q2645E	0.11
BLCA	chr1	15876554	Missense_Mutation	NA	Q253E	0.26
BLCA	chr1	15933627	In_Frame_Del	novel	D2464_S2466del	0.09
BLCA	chr1	15930825	Missense_Mutation	NA	R1529C	0.07
BLCA	chr1	15935259	Missense_Mutation	novel	I3007L	0.23
BLCA	chr1	15939528	3'UTR	novel		0.28
BLCA	chr1	15873030	Missense_Mutation	novel	R100C	0.22
BLCA	chr1	15933439	Missense_Mutation	novel	S2400Y	0.29
BLCA	chr1	15939509	3'UTR	novel		0.08
BLCA	chr1	15932651	Silent	NA	L2137L	0.32
BLCA	chr1	15932794	Missense_Mutation	NA	S2185F	0.45
BLCA	chr1	15929639	Silent	NA	Y1133Y	0.3
BRCA	chr1	15928519	Nonsense_Mutation	novel	S760*	0.25
BRCA	chr1	15934964	Silent	NA	S2908S	0.46
BRCA	chr1	15935078	Silent	NA	Q2946Q	0.23
BRCA	chr1	15933987	Nonsense_Mutation	NA	E2583*	0.21
BRCA	chr1	15933339	Frame_Shift_Del	novel	*P2367Nfs15**	0.06
BRCA	chr1	15929094	Missense_Mutation	NA	V952M	0.5
BRCA	chr1	15939322	Silent	NA	P3630P	0.52
BRCA	chr1	15935688	Missense_Mutation	novel	L3150V	0.31
BRCA	chr1	15939402	Frame_Shift_Del	novel	*M3658Pfs60**	0.26
BRCA	chr1	15937302	Missense_Mutation	rs528449671	S3389C	0.15
BRCA	chr1	15876440	Frame_Shift_Ins	NA	*H216Yfs151**	0.73
BRCA	chr1	15934777	Frame_Shift_Ins	NA	*E2846Dfs44**	0.74
BRCA	chr1	15928634	Frame_Shift_Ins	novel	*E800Gfs21**	0.43
BRCA	chr1	15933719	Frame_Shift_Del	NA	*P2495Lfs4**	0.27
BRCA	chr1	15931419	Nonsense_Mutation	NA	Q1727*	0.35
BRCA	chr1	15928410	Nonsense_Mutation	NA	R724*	0.21
BRCA	chr1	15937461	Missense_Mutation	novel	D3442V	0.06
BRCA	chr1	15929792	Frame_Shift_Del	novel	*E1185Kfs2**	0.18
BRCA	chr1	15929905	Missense_Mutation	NA	S1222F	0.15
BRCA	chr1	15931668	Missense_Mutation	rs144013241	P1810S	0.22
BRCA	chr1	15932800	Missense_Mutation	NA	S2187F	0.17
BRCA	chr1	15928198	Missense_Mutation	NA	R653Q	0.15
BRCA	chr1	15928467	Nonsense_Mutation	novel	Q743*	0.14
BRCA	chr1	15932874	Missense_Mutation	NA	E2212K	0.22
BRCA	chr1	15934074	Missense_Mutation	novel	P2612S	0.17
BRCA	chr1	15934782	Nonsense_Mutation	novel	Q2848*	0.19
BRCA	chr1	15929649	Frame_Shift_Del	novel	*R1137Vfs17**	0.09
BRCA	chr1	15920915	Missense_Mutation	NA	E561K	0.2
BRCA	chr1	15928239	Missense_Mutation	NA	D667H	0.33
BRCA	chr1	15922324	Frame_Shift_Del	NA	*F609Lfs2**	0.23
BRCA	chr1	15930517	Nonsense_Mutation	NA	L1426*	0.71
BRCA	chr1	15928150	Missense_Mutation	rs149954308	R637Q	0.09
BRCA	chr1	15930864	Nonsense_Mutation	NA	R1542*	0.22
BRCA	chr1	15933609	Missense_Mutation	NA	D2457N	0.53
BRCA	chr1	15933738	Missense_Mutation	NA	E2500Q	0.5
BRCA	chr1	15933987	Missense_Mutation	NA	E2583K	0.5
BRCA	chr1	15934319	Silent	NA	L2693L	0.5
BRCA	chr1	15935825	Silent	NA	V3195V	0.5
BRCA	chr1	15932414	Frame_Shift_Del	NA	*P2059Kfs3**	0.37
BRCA	chr1	15932165	Frame_Shift_Del	NA	*K1976Afs3**	0.33
BRCA	chr1	15934471	Missense_Mutation	NA	G2744D	0.43
BRCA	chr1	15928184	Silent	NA	R648R	0.18
BRCA	chr1	15876299	Missense_Mutation	NA	D168N	0.41
BRCA	chr1	15936120	Nonsense_Mutation	NA	Q3294*	0.21
BRCA	chr1	15933441	Missense_Mutation	novel	D2401N	0.06
BRCA	chr1	15932547	Frame_Shift_Ins	NA	*A2105Gfs18**	0.22
BRCA	chr1	15933926	Silent	novel	V2562V	0.08
BRCA	chr1	15932309	Silent	NA	V2023V	0.13
BRCA	chr1	15928637	Silent	NA	P799P	0.19
BRCA	chr1	15931347	Frame_Shift_Del	NA	*P1704Qfs11**	0.15
BRCA	chr1	15934394	Silent	NA	V2718V	0.3
BRCA	chr1	15932169	Missense_Mutation	NA	P1977S	0.29
CESC	chr1	15932148	Nonsense_Mutation	novel	E1970*	0.36
CESC	chr1	15916133	Missense_Mutation	NA	E417K	0.26
CESC	chr1	15916139	Missense_Mutation	NA	E419K	0.27
CESC	chr1	15937968	Missense_Mutation	NA	E3556K	0.37
CESC	chr1	15932577	Missense_Mutation	NA	E2113Q	0.19
CESC	chr1	15935344	Nonsense_Mutation	NA	S3035*	0.14
CESC	chr1	15935564	Missense_Mutation	NA	I3108M	0.23
CESC	chr1	15928344	Nonsense_Mutation	novel	R702*	0.36
CESC	chr1	15919001	Missense_Mutation	NA	K491Q	0.39
CESC	chr1	15873114	Missense_Mutation	rs751080105	R128C	0.5
CESC	chr1	15940346	3'UTR	novel		0.26
CESC	chr1	15911273	Missense_Mutation	NA	Q405H	0.28
CESC	chr1	15933801	Missense_Mutation	NA	D2521H	0.32
CESC	chr1	15848136	Silent	novel	I23I	0.28
CESC	chr1	15933018	Missense_Mutation	NA	E2260K	0.2
CESC	chr1	15929730	Missense_Mutation	NA	D1164N	0.28
CESC	chr1	15935825	Silent	novel	V3195V	0.25
CESC	chr1	15936168	Missense_Mutation	rs747459170	D3310N	0.29
CESC	chr1	15874162	Intron	novel		0.41
CESC	chr1	15931074	Missense_Mutation	NA	D1612Y	0.33
CESC	chr1	15931398	Missense_Mutation	NA	E1720Q	0.49
CESC	chr1	15937434	Missense_Mutation	novel	S3433F	0.37
CESC	chr1	15936236	Frame_Shift_Ins	novel	*L3333Sfs15**	0.1
CESC	chr1	15929566	Nonsense_Mutation	novel	S1109*	0.09
CESC	chr1	15920971	Silent	novel	G579G	0.4
CESC	chr1	15931859	Silent	NA	E1873E	0.13
CESC	chr1	15932252	Silent	rs146430628	P2004P	0.22
CESC	chr1	15936150	Missense_Mutation	NA	Q3304E	0.45
CESC	chr1	15929406	Frame_Shift_Del	novel	*R1056Tfs2**	0.45
CESC	chr1	15847885	5'UTR	novel		0.55
CESC	chr1	15934229	In_Frame_Del	novel	N2666_V2672del	0.33
CESC	chr1	15929748	Nonsense_Mutation	NA	R1170*	0.23
CESC	chr1	15940034	3'UTR	novel		0.47
CESC	chr1	15929360	Silent	rs755049645	V1040V	0.33
CESC	chr1	15928331	Nonsense_Mutation	NA	Y697*	0.33
CESC	chr1	15929613	Missense_Mutation	novel	E1125Q	0.5
CESC	chr1	15929760	Missense_Mutation	NA	E1174K	0.36
CESC	chr1	15929808	Missense_Mutation	NA	E1190Q	0.33
CESC	chr1	15930006	Missense_Mutation	novel	E1256K	0.4
CESC	chr1	15930972	Missense_Mutation	NA	E1578Q	0.67
CHOL	chr1	15939931	3'UTR	novel		0.38
CHOL	chr1	15939933	3'UTR	novel		0.4
COAD	chr1	15874316	Intron	novel		0.11
COAD	chr1	15932412	Missense_Mutation	rs200349060	A2058T	0.12
COAD	chr1	15931463	Silent	NA	S1741S	0.41
COAD	chr1	15932352	Missense_Mutation	novel	G2038R	0.06
COAD	chr1	15928591	Missense_Mutation	rs181758065	R784H	0.27
COAD	chr1	15932879	Frame_Shift_Del	NA	*E2214Afs11**	0.37
COAD	chr1	15933951	In_Frame_Ins	novel	P2574_P2575dup	0.21
COAD	chr1	15932947	Missense_Mutation	rs768277125	P2236L	0.13
COAD	chr1	15874153	Intron	novel		0.35
COAD	chr1	15874344	Intron	novel		0.2
COAD	chr1	15872824	Missense_Mutation	novel	R31H	0.42
COAD	chr1	15937258	Silent	rs151095742	L3374L	0.09
COAD	chr1	15935992	Missense_Mutation	novel	P3251H	0.33
COAD	chr1	15920892	Missense_Mutation	NA	G553A	0.3
COAD	chr1	15928999	Missense_Mutation	novel	S920F	0.25
COAD	chr1	15930255	Missense_Mutation	rs760134992	R1339C	0.08
COAD	chr1	15939422	Missense_Mutation	novel	V3664L	0.16
COAD	chr1	15932618	Missense_Mutation	novel	S2126R	0.1
COAD	chr1	15931423	Missense_Mutation	rs143503694	P1728L	0.43
COAD	chr1	15932548	Frame_Shift_Del	novel	*A2105Lfs33**	0.46
COAD	chr1	15936185	Frame_Shift_Del	NA	*P3317Rfs83**	0.36
COAD	chr1	15928597	Frame_Shift_Ins	novel	*N788Kfs2**	0.3
COAD	chr1	15931816	Frame_Shift_Del	NA	*G1860Efs9**	0.33
COAD	chr1	15876614	Missense_Mutation	novel	G273S	0.32
COAD	chr1	15928396	Missense_Mutation	NA	R719M	0.42
COAD	chr1	15929388	Frame_Shift_Del	NA	*I1052Sfs40**	0.35
COAD	chr1	15938005	Missense_Mutation	novel	T3568M	0.21
COAD	chr1	15928434	Nonsense_Mutation	NA	R732*	0.27
COAD	chr1	15933336	Missense_Mutation	novel	S2366C	0.45
COAD	chr1	15932399	Frame_Shift_Del	NA	*P2055Lfs9**	0.32
COAD	chr1	15932985	Frame_Shift_Del	NA	*A2251Qfs102**	0.34
COAD	chr1	15934608	Missense_Mutation	NA	M2790V	0.26
COAD	chr1	15939485	3'UTR	novel		0.08
COAD	chr1	15918983	Missense_Mutation	novel	D485N	0.24
COAD	chr1	15935129	Silent	NA	P2963P	0.49
COAD	chr1	15930688	Missense_Mutation	novel	V1483A	0.08
COAD	chr1	15932985	Frame_Shift_Del	NA	*A2251Qfs102**	0.29
COAD	chr1	15932747	Missense_Mutation	novel	M2169I	0.07
COAD	chr1	15935621	Silent	NA	Q3127Q	0.25
COAD	chr1	15934640	Silent	rs774526480	A2800A	0.36
COAD	chr1	15931745	Silent	rs753572544	I1835I	0.44
COAD	chr1	15876279	Missense_Mutation	NA	R161Q	0.67
COAD	chr1	15929710	Frame_Shift_Del	novel	*I1159Lfs28**	0.25
COAD	chr1	15876679	Splice_Site	novel	X294_splice	0.07
COAD	chr1	15911210	Silent	NA	R384R	0.21
COAD	chr1	15928226	Silent	novel	E662E	0.08
COAD	chr1	15932264	Silent	NA	A2008A	0.16
COAD	chr1	15931170	Missense_Mutation	novel	V1644I	0.18
COAD	chr1	15876609	Missense_Mutation	NA	G271D	0.31
COAD	chr1	15933400	Missense_Mutation	NA	S2387N	0.27
COAD	chr1	15932394	Frame_Shift_Del	novel	*N2053Tfs11**	0.43
COAD	chr1	15935920	Missense_Mutation	novel	Q3227R	0.42
COAD	chr1	15928770	Nonsense_Mutation	NA	R844*	0.23
COAD	chr1	15916197	Missense_Mutation	NA	R438I	0.15
COAD	chr1	15928610	Missense_Mutation	NA	K790N	0.3
COAD	chr1	15930201	Missense_Mutation	rs781238166	A1321T	0.17
COAD	chr1	15933259	Missense_Mutation	rs747993146	R2340H	0.08
COAD	chr1	15872960	Silent	NA	T76T	0.2
COAD	chr1	15934501	Missense_Mutation	rs146330997	T2754M	0.27
COAD	chr1	15928648	Missense_Mutation	novel	E803G	0.24
COAD	chr1	15932985	Frame_Shift_Del	NA	*A2251Qfs102**	0.28
DLBC	chr1	15930492	Nonsense_Mutation	novel	R1418*	0.19
DLBC	chr1	15928893	Nonsense_Mutation	novel	E885*	0.1
DLBC	chr1	15909361	Nonsense_Mutation	NA	R308*	0.24	RRM_5
ESCA	chr1	15934502	Silent	novel	T2754T	0.35
ESCA	chr1	15937475	Missense_Mutation	novel	L3447V	0.16
ESCA	chr1	15939933	3'UTR	novel		0.26
ESCA	chr1	15939927	3'UTR	novel		0.2
GBM	chr1	15937436	Missense_Mutation	novel	P3434A	0.13
GBM	chr1	15935711	Missense_Mutation	novel	E3157D	0.29
GBM	chr1	15934497	Missense_Mutation	novel	V2753I	0.47
GBM	chr1	15932478	Missense_Mutation	novel	S2080A	0.11
GBM	chr1	15937865	Silent	novel	A3521A	0.04
GBM	chr1	15930206	Missense_Mutation	novel	D1322E	0.11
GBM	chr1	15932494	Nonsense_Mutation	novel	L2085*	0.23
GBM	chr1	15933033	Frame_Shift_Del	novel	*T2265Qfs88**	0.4
GBM	chr1	15873031	Missense_Mutation	rs146693537	R100H	0.16
GBM	chr1	15930612	Missense_Mutation	NA	R1458C	0.48
GBM	chr1	15930952	Missense_Mutation	novel	S1571N	0.2
GBM	chr1	15933082	Missense_Mutation	novel	S2281Y	0.2
GBM	chr1	15934939	Missense_Mutation	novel	S2900L	0.42
GBM	chr1	15935599	Missense_Mutation	rs749920639	P3120L	0.45
GBM	chr1	15935866	Missense_Mutation	novel	Q3209L	0.32
GBM	chr1	15936000	Missense_Mutation	novel	V3254L	0.51
GBM	chr1	15938844	Missense_Mutation	novel	I3611F	0.14
GBM	chr1	15934666	Missense_Mutation	novel	N2809I	0.25
GBM	chr1	15935156	Frame_Shift_Ins	novel	*L2973Tfs211**	0.6
GBM	chr1	15936142	Missense_Mutation	novel	E3301G	0.07
GBM	chr1	15928208	Missense_Mutation	novel	E656D	0.18
GBM	chr1	15934734	Missense_Mutation	NA	A2832T	0.58
GBM	chr1	15933470	Missense_Mutation	novel	N2410K	0.08
GBM	chr1	15932652	Nonsense_Mutation	novel	K2138*	0.16
GBM	chr1	15932909	Silent	novel	I2223I	0.19
GBM	chr1	15930396	Missense_Mutation	rs369228133	G1386S	0.04
GBM	chr1	15936217	Missense_Mutation	novel	P3326L	0.41
GBM	chr1	15935979	Missense_Mutation	novel	P3247S	0.87
GBM	chr1	15872947	Missense_Mutation	NA	R72T	0.14
GBM	chr1	15931989	Missense_Mutation	NA	R1917C	0.38
GBM	chr1	15936055	Missense_Mutation	novel	V3272G	0.12
HNSC	chr1	15876524	Silent	NA	R243R	0.32
HNSC	chr1	15930608	Silent	novel	S1456S	0.09
HNSC	chr1	15873013	Frame_Shift_Ins	novel	*V95Efs8**	0.17
HNSC	chr1	15873015	In_Frame_Ins	novel	V95delinsEGMYFKL	0.13
HNSC	chr1	15932074	Missense_Mutation	novel	P1945L	0.24
HNSC	chr1	15932794	Missense_Mutation	novel	S2185Y	0.24
HNSC	chr1	15933641	Silent	novel	I2467I	0.15
HNSC	chr1	15918978	Missense_Mutation	novel	Y483C	0.28
HNSC	chr1	15929728	Missense_Mutation	novel	I1163N	0.15
HNSC	chr1	15928117	Missense_Mutation	NA	Y626C	0.44
HNSC	chr1	15934929	Missense_Mutation	novel	P2897A	0.18
HNSC	chr1	15928983	Nonsense_Mutation	novel	Q915*	0.07
HNSC	chr1	15928122	Missense_Mutation	novel	Q628E	0.36
HNSC	chr1	15930032	Silent	novel	V1264V	0.2
HNSC	chr1	15933522	Missense_Mutation	rs370674242	P2428S	0.65
HNSC	chr1	15932394	Nonsense_Mutation	novel	K2052*	0.74
HNSC	chr1	15933682	Missense_Mutation	novel	S2481L	0.22
HNSC	chr1	15928394	Silent	novel	E718E	0.2
HNSC	chr1	15933716	Missense_Mutation	rs771418115	Q2492H	0.23
HNSC	chr1	15930289	Missense_Mutation	novel	R1350K	0.31
HNSC	chr1	15928534	Missense_Mutation	novel	S765N	0.15
HNSC	chr1	15876533	Missense_Mutation	novel	H246Y	0.53
HNSC	chr1	15936226	Missense_Mutation	novel	S3329F	0.13
HNSC	chr1	15934038	Missense_Mutation	novel	E2600K	0.11
HNSC	chr1	15930692	Missense_Mutation	novel	D1484E	0.11
HNSC	chr1	15931944	Missense_Mutation	rs776525901	R1902W	0.26
HNSC	chr1	15931203	Missense_Mutation	novel	E1655Q	0.04
HNSC	chr1	15931847	Missense_Mutation	novel	K1869N	0.14
HNSC	chr1	15929597	Missense_Mutation	novel	L1119F	0.42
HNSC	chr1	15932658	Missense_Mutation	novel	D2140H	0.18
HNSC	chr1	15928994	Missense_Mutation	novel	Q918H	0.19
HNSC	chr1	15932083	Missense_Mutation	NA	P1948L	0.42
HNSC	chr1	15937924	Missense_Mutation	novel	S3541F	0.34
HNSC	chr1	15931751	Silent	rs374972567	E1837E	0.08
KICH	chr1	15929624	Silent	rs140864111	D1128D	0.16
KIRC	chr1	15931499	Silent	rs766644588	P1753P	0.17
KIRC	chr1	15931500	Missense_Mutation	NA	D1754N	0.16
KIRC	chr1	15935581	Missense_Mutation	NA	P3114R	0.2
KIRC	chr1	15932946	Missense_Mutation	NA	P2236S	0.32
KIRC	chr1	15935098	Missense_Mutation	rs776343165	I2953T	0.56
KIRC	chr1	15929010	Missense_Mutation	NA	P924S	0.18
KIRC	chr1	15930609	Missense_Mutation	NA	S1457A	0.04
KIRC	chr1	15928162	Frame_Shift_Del	novel	*T641Ifs3**	0.18
KIRC	chr1	15928828	Missense_Mutation	NA	D863A	0.23
KIRC	chr1	15929722	Missense_Mutation	NA	I1161T	0.82
KIRC	chr1	15909467	Missense_Mutation	novel	P343L	0.27	RRM_5
KIRC	chr1	15933817	Missense_Mutation	NA	D2526A	0.33
KIRC	chr1	15929625	Missense_Mutation	rs759801779	V1129I	0.29
KIRC	chr1	15930043	Missense_Mutation	rs748429563	S1268F	0.24
KIRC	chr1	15873105	Nonsense_Mutation	NA	R125*	0.14
KIRP	chr1	15873049	Missense_Mutation	novel	G106V	0.26
KIRP	chr1	15930910	Missense_Mutation	novel	S1557F	0.48
KIRP	chr1	15935009	Silent	novel	V2923V	0.41
KIRP	chr1	15933968	Silent	NA	V2576V	0.38
KIRP	chr1	15931416	Missense_Mutation	NA	D1726N	0.1
KIRP	chr1	15931842	Missense_Mutation	NA	L1868V	0.74
KIRP	chr1	15939536	3'UTR	novel		0.53
KIRP	chr1	15932153	Silent	NA	P1971P	0.33
KIRP	chr1	15928405	Missense_Mutation	rs765438846	I722T	0.08
KIRP	chr1	15938875	Missense_Mutation	novel	Q3621R	0.77
KIRP	chr1	15932328	Missense_Mutation	novel	P2030S	0.39
LAML	chr1	15934207	Missense_Mutation	novel	G2656A	0.2
LAML	chr1	15936164	Silent	rs779804838	Y3308Y	0.56
LAML	chr1	15928189	Missense_Mutation	NA	Y650S	0.23
LAML	chr1	15933743	Nonsense_Mutation	NA	W2501*	0.38
LAML	chr1	15876594	Missense_Mutation	NA	T266R	0.55
LAML	chr1	15930285	Missense_Mutation	novel	G1349C	0.25
LAML	chr1	15931497	Missense_Mutation	novel	P1753S	0.05
LAML	chr1	15934044	Missense_Mutation	novel	L2602V	0.41
LGG	chr1	15876483	Missense_Mutation	rs139125517	R229Q	0.32
LGG	chr1	15874242	Intron	novel		0.09
LGG	chr1	15909434	Missense_Mutation	rs779128550	R332H	0.32	RRM_5
LGG	chr1	15918952	Silent	novel	G474G	0.1
LGG	chr1	15928244	Silent	novel	Y668Y	0.09
LGG	chr1	15933862	Missense_Mutation	novel	P2541H	0.1
LGG	chr1	15934346	Silent	rs751786011	G2702G	0.27
LGG	chr1	15916143	Missense_Mutation	NA	N420S	0.06
LGG	chr1	15930700	Frame_Shift_Ins	novel	*R1488Sfs16**	0.08
LIHC	chr1	15937198	Silent	novel	P3354P	0.51
LIHC	chr1	15934317	Silent	NA	L2693L	0.16
LIHC	chr1	15929406	Nonsense_Mutation	NA	R1056*	0.39
LIHC	chr1	15931163	Missense_Mutation	NA	S1641R	0.31
LIHC	chr1	15930053	Missense_Mutation	NA	E1271D	0.28
LIHC	chr1	15932835	Missense_Mutation	rs550359408	A2199S	0.35
LIHC	chr1	15935367	Missense_Mutation	NA	S3043G	0.2
LIHC	chr1	15928954	Missense_Mutation	rs768180417	N905S	0.25
LIHC	chr1	15873021	Missense_Mutation	novel	I97V	0.46
LUAD	chr1	15931575	Missense_Mutation	NA	A1779S	0.1
LUAD	chr1	15928744	Missense_Mutation	NA	S835C	0.21
LUAD	chr1	15928833	Missense_Mutation	NA	E865Q	0.14
LUAD	chr1	15928950	Missense_Mutation	NA	D904H	0.14
LUAD	chr1	15931335	Missense_Mutation	NA	Q1699E	0.15
LUAD	chr1	15937327	Silent	novel	T3397T	0.18
LUAD	chr1	15939334	Silent	rs746873132	F3634F	0.33
LUAD	chr1	15932069	Silent	rs751161622	A1943A	0.17
LUAD	chr1	15933699	Frame_Shift_Del	NA	*I2489Sfs10**	0.09
LUAD	chr1	15933787	Missense_Mutation	rs778553422	P2516L	0.21
LUAD	chr1	15916168	Missense_Mutation	NA	R428S	0.23
LUAD	chr1	15929340	Missense_Mutation	NA	E1034K	0.06
LUAD	chr1	15933122	Frame_Shift_Del	novel	*P2295Qfs58**	0.17
LUAD	chr1	15929043	Missense_Mutation	NA	V935F	0.15
LUAD	chr1	15932042	Missense_Mutation	novel	L1934F	0.29
LUAD	chr1	15929915	Silent	NA	S1225S	0.11
LUAD	chr1	15935124	Missense_Mutation	NA	D2962N	0.51
LUAD	chr1	15936042	Missense_Mutation	rs200479229	R3268C	0.8
LUAD	chr1	15930706	Missense_Mutation	NA	P1489R	0.31
LUAD	chr1	15929562	Missense_Mutation	novel	P1108A	0.33
LUAD	chr1	15930434	Missense_Mutation	NA	L1398F	0.26
LUAD	chr1	15928524	Missense_Mutation	novel	R762W	0.27
LUAD	chr1	15930768	In_Frame_Ins	novel	K1511_K1512insNK	0.09
LUAD	chr1	15934638	Missense_Mutation	NA	A2800P	0.11
LUAD	chr1	15935229	Missense_Mutation	NA	E2997K	0.21
LUAD	chr1	15937611	Missense_Mutation	NA	S3492Y	0.09
LUAD	chr1	15934244	Silent	novel	L2668L	0.11
LUAD	chr1	15933466	Frame_Shift_Del	novel	*N2410Kfs46**	0.12
LUAD	chr1	15932735	Silent	rs781759133	L2165L	0.32
LUAD	chr1	15932252	Silent	rs146430628	P2004P	0.24
LUAD	chr1	15929150	Silent	novel	A970A	0.59
LUAD	chr1	15934110	Missense_Mutation	novel	R2624G	0.11
LUAD	chr1	15929422	Missense_Mutation	NA	A1061V	0.08
LUAD	chr1	15931563	Missense_Mutation	rs766847660	E1775K	0.19
LUAD	chr1	15930000	Missense_Mutation	novel	D1254H	0.1
LUAD	chr1	15930960	Missense_Mutation	rs138972634	D1574N	0.18
LUSC	chr1	15873028	Missense_Mutation	novel	S99Y	0.05
LUSC	chr1	15939449	3'UTR	novel		0.32
LUSC	chr1	15874117	Intron	novel		0.72
LUSC	chr1	15931311	Missense_Mutation	rs532673015	P1691S	0.63
LUSC	chr1	15911279	Missense_Mutation	novel	E407D	0.46
LUSC	chr1	15931281	Missense_Mutation	novel	E1681Q	0.04
LUSC	chr1	15937897	Missense_Mutation	novel	V3532A	0.12
LUSC	chr1	15920928	Missense_Mutation	novel	A565V	0.23
LUSC	chr1	15928582	Missense_Mutation	rs778639822	R781H	0.18
LUSC	chr1	15931409	Silent	NA	S1723S	0.5
LUSC	chr1	15931035	Missense_Mutation	NA	E1599Q	0.05
LUSC	chr1	15931847	Silent	novel	K1869K	0.08
LUSC	chr1	15911232	Missense_Mutation	novel	A392P	0.08
LUSC	chr1	15911233	Nonsense_Mutation	novel	*A392_L393insSYF**	0.08
LUSC	chr1	15876383	Missense_Mutation	novel	A196T	0.35
LUSC	chr1	15930409	Missense_Mutation	novel	S1390Y	0.36
LUSC	chr1	15934196	Silent	rs755358455	S2652S	0.18
LUSC	chr1	15930195	Nonsense_Mutation	NA	Q1319*	0.18
LUSC	chr1	15931284	Missense_Mutation	novel	E1682Q	0.23
LUSC	chr1	15931614	Missense_Mutation	rs537211881	E1792K	0.22
LUSC	chr1	15932613	Missense_Mutation	novel	E2125K	0.22
LUSC	chr1	15932615	Silent	novel	E2125E	0.22
LUSC	chr1	15932972	Missense_Mutation	novel	Q2244H	0.19
LUSC	chr1	15933138	Nonsense_Mutation	novel	E2300*	0.22
LUSC	chr1	15934706	Silent	rs138278143	Q2822Q	0.22
LUSC	chr1	15937908	Missense_Mutation	NA	R3536G	0.42
LUSC	chr1	15929939	Silent	NA	V1233V	0.34
LUSC	chr1	15935165	Silent	rs150393064	P2975P	0.19
LUSC	chr1	15935166	Missense_Mutation	NA	A2976T	0.2
LUSC	chr1	15935441	Silent	rs769131237	F3067F	0.18
LUSC	chr1	15929387	Silent	novel	S1049S	0.33
LUSC	chr1	15928747	Missense_Mutation	NA	S836L	0.28
LUSC	chr1	15932913	Missense_Mutation	NA	D2225N	0.49
LUSC	chr1	15933235	Missense_Mutation	rs764509266	R2332H	0.1
LUSC	chr1	15930028	Missense_Mutation	novel	S1263I	0.3
LUSC	chr1	15934444	Missense_Mutation	rs754688541	T2735I	0.79
OV	chr1	15931818	Missense_Mutation	novel	G1860R	0.05
OV	chr1	15937873	Missense_Mutation	novel	L3524P	0.07
OV	chr1	15928796	Silent	NA	R852R	0.06
OV	chr1	15932223	Missense_Mutation	NA	P1995S	0.68
OV	chr1	15933459	Missense_Mutation	novel	S2407T	0.07
OV	chr1	15939333	Missense_Mutation	novel	F3634S	0.03
OV	chr1	15939459	3'UTR	novel		0.37
OV	chr1	15928410	Silent	novel	R724R	0.05
OV	chr1	15939351	Missense_Mutation	novel	S3640Y	0.07
OV	chr1	15929224	Missense_Mutation	novel	A995E	0.05
OV	chr1	15934302	Missense_Mutation	NA	G2688R	0.87
OV	chr1	15938761	Missense_Mutation	NA	R3583P	0.06
OV	chr1	15933310	Missense_Mutation	novel	P2357H	0.08
OV	chr1	15936206	Missense_Mutation	novel	H3322Q	0.05
OV	chr1	15937290	Missense_Mutation	novel	M3385R	0.19
OV	chr1	15939411	Missense_Mutation	novel	V3660G	0.18
OV	chr1	15932513	Silent	novel	A2091A	0.09
OV	chr1	15932749	Missense_Mutation	novel	E2170V	0.14
OV	chr1	15932496	Missense_Mutation	novel	A2086P	0.13
OV	chr1	15920889	Missense_Mutation	NA	K552R	0.47
OV	chr1	15916269	Missense_Mutation	novel	G462E	0.06
OV	chr1	15934787	Silent	NA	Q2849Q	0.17
OV	chr1	15938787	Missense_Mutation	novel	T3592A	0.03
OV	chr1	15935748	Missense_Mutation	novel	T3170S	0.11
OV	chr1	15876549	Missense_Mutation	NA	R251T	0.23
OV	chr1	15929946	Missense_Mutation	NA	D1236H	0.47
OV	chr1	15872854	Missense_Mutation	novel	R41M	0.05
OV	chr1	15932472	Missense_Mutation	novel	G2078R	0.07
OV	chr1	15933842	Silent	NA	L2534L	0.3
OV	chr1	15939364	Silent	novel	P3644P	0.15
OV	chr1	15934602	Missense_Mutation	NA	G2788R	0.11
OV	chr1	15928814	Silent	novel	S858S	0.3
OV	chr1	15874333	Intron	rs761555839		0.26
OV	chr1	15932633	Silent	novel	D2131D	0.08
OV	chr1	15933285	Missense_Mutation	novel	V2349M	0.3
OV	chr1	15932697	Missense_Mutation	rs761978747	V2153M	0.16
OV	chr1	15928996	In_Frame_Ins	novel	V919_S920insCWSG	0.1
OV	chr1	15928998	Frame_Shift_Ins	novel	*S920Wfs24**	0.06
OV	chr1	15930219	Frame_Shift_Ins	novel	*K1327Rfs8**	0.05
OV	chr1	15930221	Frame_Shift_Ins	novel	*L1328Vfs10**	0.05
OV	chr1	15874304	Intron	novel		0.3
OV	chr1	15937223	Missense_Mutation	novel	A3363S	0.15
OV	chr1	15932508	Missense_Mutation	novel	S2090P	0.05
PAAD	chr1	15935523	Nonsense_Mutation	novel	Q3095*	0.13
PAAD	chr1	15937824	Missense_Mutation	novel	V3508M	0.18
PAAD	chr1	15928128	Missense_Mutation	rs749814808	R630C	0.21
PAAD	chr1	15928668	Missense_Mutation	novel	R810W	0.1
PAAD	chr1	15931961	Silent	novel	V1907V	0.09
PAAD	chr1	15937909	Missense_Mutation	rs762946669	R3536Q	0.19
PAAD	chr1	15931436	Frame_Shift_Del	novel	*A1733Lfs15**	0.18
PCPG	chr1	15935266	Missense_Mutation	novel	A3009G	0.2
PRAD	chr1	15930599	Silent	NA	S1453S	0.31
PRAD	chr1	15935806	Missense_Mutation	NA	Y3189C	0.11
PRAD	chr1	15931390	Missense_Mutation	rs779004613	A1717V	0.19
PRAD	chr1	15930663	Nonsense_Mutation	NA	R1475*	0.06
PRAD	chr1	15932548	Frame_Shift_Del	novel	*A2105Lfs33**	0.29
PRAD	chr1	15932985	Frame_Shift_Del	NA	*A2251Qfs102**	0.25
PRAD	chr1	15929306	Frame_Shift_Del	novel	*S1023Ffs3**	0.07
PRAD	chr1	15934331	Silent	novel	V2697V	0.12
PRAD	chr1	15929005	Missense_Mutation	rs140341054	T922M	0.39
PRAD	chr1	15935814	Missense_Mutation	novel	P3192S	0.16
PRAD	chr1	15937950	Missense_Mutation	novel	A3550T	0.42
PRAD	chr1	15938760	Missense_Mutation	rs749521610	R3583C	0.31
READ	chr1	15928150	Missense_Mutation	rs149954308	R637Q	0.3
READ	chr1	15930317	Silent	novel	I1359I	0.13
READ	chr1	15932500	Missense_Mutation	novel	V2087A	0.05
READ	chr1	15939431	3'UTR	novel		0.15
READ	chr1	15929471	Silent	novel	G1077G	0.53
READ	chr1	15929566	Nonsense_Mutation	novel	S1109*	0.37
READ	chr1	15930255	Missense_Mutation	NA	R1339S	0.39
READ	chr1	15931429	Missense_Mutation	novel	Y1730S	0.41
READ	chr1	15932439	Missense_Mutation	NA	P2067T	0.33
READ	chr1	15932578	Missense_Mutation	novel	E2113G	0.44
READ	chr1	15938790	Missense_Mutation	novel	E3593K	0.43
READ	chr1	15929367	Nonsense_Mutation	NA	E1043*	0.36
READ	chr1	15931706	Silent	NA	K1822K	0.36
SARC	chr1	15933796	Missense_Mutation	novel	P2519L	0.15
SARC	chr1	15938822	Silent	novel	L3603L	0.27
SARC	chr1	15873030	Missense_Mutation	novel	R100C	0.31
SARC	chr1	15934751	Silent	NA	I2837I	0.42
SARC	chr1	15933982	Missense_Mutation	novel	P2581L	0.24
SKCM	chr1	15928835	Silent	NA	E865E	0.45
SKCM	chr1	15935972	Silent	NA	T3244T	0.69
SKCM	chr1	15932544	Missense_Mutation	novel	P2102S	0.46
SKCM	chr1	15932545	Missense_Mutation	novel	P2102L	0.46
SKCM	chr1	15928836	Missense_Mutation	NA	G866R	0.17
SKCM	chr1	15936139	Missense_Mutation	NA	G3300E	0.29
SKCM	chr1	15933897	Missense_Mutation	rs115746085	S2553G	0.33
SKCM	chr1	15932464	Nonsense_Mutation	NA	S2075*	0.15
SKCM	chr1	15935997	Missense_Mutation	NA	P3253T	0.5
SKCM	chr1	15931682	Silent	NA	K1814K	0.42
SKCM	chr1	15937949	Silent	rs780849980	I3549I	0.17
SKCM	chr1	15872912	Silent	novel	Q60Q	0.05
SKCM	chr1	15931147	Missense_Mutation	novel	S1636F	0.37
SKCM	chr1	15933472	Missense_Mutation	novel	S2411L	0.36
SKCM	chr1	15872847	Missense_Mutation	NA	P39S	0.28
SKCM	chr1	15909361	Nonsense_Mutation	NA	R308*	0.07	RRM_5
SKCM	chr1	15929563	Missense_Mutation	NA	P1108L	0.26
SKCM	chr1	15930122	Silent	NA	V1294V	0.27
SKCM	chr1	15930447	Nonsense_Mutation	NA	R1403*	0.37
SKCM	chr1	15929729	Silent	rs775651371	I1163I	0.5
SKCM	chr1	15928796	Silent	NA	R852R	0.76
SKCM	chr1	15931462	Missense_Mutation	rs762412019	S1741L	0.11
SKCM	chr1	15935045	Silent	NA	G2935G	0.22
SKCM	chr1	15932009	Silent	rs574715364	P1923P	0.06
SKCM	chr1	15937263	Missense_Mutation	NA	Q3376R	0.05
SKCM	chr1	15928773	Missense_Mutation	NA	E845K	0.48
SKCM	chr1	15931745	Silent	rs753572544	I1835I	0.38
SKCM	chr1	15938771	Silent	NA	E3586E	0.36
SKCM	chr1	15932865	Nonsense_Mutation	NA	Q2209*	0.36
SKCM	chr1	15920972	Nonsense_Mutation	novel	*N580Ifs6**	0.32
SKCM	chr1	15920974	Silent	novel	N580N	0.07
SKCM	chr1	15934751	Silent	NA	I2837I	0.54
SKCM	chr1	15876351	Missense_Mutation	NA	A185V	0.59
SKCM	chr1	15931115	Silent	NA	E1625E	0.55
SKCM	chr1	15874395	Intron	rs763348381		0.25
SKCM	chr1	15930612	Missense_Mutation	NA	R1458C	0.87
SKCM	chr1	15932714	Silent	rs778641327	P2158P	0.54
SKCM	chr1	15936223	Missense_Mutation	novel	A3328V	0.39
SKCM	chr1	15931113	Nonsense_Mutation	NA	E1625*	0.66
SKCM	chr1	15929428	Missense_Mutation	NA	P1063L	0.22
SKCM	chr1	15930385	Missense_Mutation	NA	S1382F	0.09
SKCM	chr1	15937169	Missense_Mutation	NA	P3345S	0.22
SKCM	chr1	15937170	Missense_Mutation	rs35291379	P3345L	0.23
SKCM	chr1	15932839	Missense_Mutation	NA	P2200L	0.66
SKCM	chr1	15934848	Missense_Mutation	NA	G2870S	0.15
SKCM	chr1	15931469	Silent	NA	S1743S	0.15
SKCM	chr1	15936179	Silent	rs138629522	T3313T	0.28
SKCM	chr1	15930965	Silent	NA	S1575S	0.37
SKCM	chr1	15920923	Missense_Mutation	novel	E563D	0.28
SKCM	chr1	15933543	Missense_Mutation	NA	P2435S	0.55
SKCM	chr1	15874381	Intron	novel		0.25
SKCM	chr1	15929114	Silent	NA	L958L	0.09
SKCM	chr1	15935144	Silent	rs145129045	I2968I	0.42
SKCM	chr1	15933934	Missense_Mutation	NA	A2565V	0.21
SKCM	chr1	15873055	Missense_Mutation	NA	R108K	0.09
SKCM	chr1	15936188	Silent	NA	P3316P	0.21
SKCM	chr1	15916151	Missense_Mutation	NA	R423C	0.29
SKCM	chr1	15930825	Missense_Mutation	NA	R1529C	0.16
SKCM	chr1	15929192	Silent	NA	R984R	0.46
SKCM	chr1	15932821	Frame_Shift_Ins	novel	*G2197Dfs159**	0.09
SKCM	chr1	15932481	Nonsense_Mutation	NA	R2081*	0.14
SKCM	chr1	15931370	Missense_Mutation	NA	K1710N	0.21
SKCM	chr1	15931422	Missense_Mutation	NA	P1728A	0.31
SKCM	chr1	15876417	Missense_Mutation	NA	E207G	0.23
SKCM	chr1	15932101	Missense_Mutation	NA	P1954L	0.17
SKCM	chr1	15935262	Missense_Mutation	NA	P3008S	0.13
SKCM	chr1	15933862	Missense_Mutation	NA	P2541L	0.17
SKCM	chr1	15931010	Silent	NA	L1590L	0.35
SKCM	chr1	15876317	Nonsense_Mutation	NA	R174*	0.16
SKCM	chr1	15936246	Missense_Mutation	rs369486221	R3336W	0.32
SKCM	chr1	15937949	Silent	rs780849980	I3549I	0.17
SKCM	chr1	15918927	Missense_Mutation	novel	D466G	0.79
SKCM	chr1	15929983	Missense_Mutation	NA	S1248L	0.42
SKCM	chr1	15933027	Missense_Mutation	NA	M2263L	0.18
SKCM	chr1	15931604	Silent	novel	N1788N	0.3
SKCM	chr1	15932198	Silent	novel	S1986S	0.49
SKCM	chr1	15934629	Missense_Mutation	novel	P2797S	0.45
SKCM	chr1	15930886	Missense_Mutation	NA	K1549I	0.13
SKCM	chr1	15933093	Missense_Mutation	NA	P2285S	0.4
STAD	chr1	15931958	Silent	rs765166166	S1906S	0.2
STAD	chr1	15932985	Frame_Shift_Del	NA	*A2251Qfs102**	0.11
STAD	chr1	15931314	Missense_Mutation	novel	A1692T	0.29
STAD	chr1	15932985	Frame_Shift_Del	NA	*A2251Qfs102**	0.23
STAD	chr1	15929288	Frame_Shift_Del	novel	*K1018Sfs13**	0.27
STAD	chr1	15930485	Silent	rs538594632	L1415L	0.06
STAD	chr1	15934111	Missense_Mutation	rs200512596	R2624Q	0.31
STAD	chr1	15933963	Missense_Mutation	NA	P2575T	0.19
STAD	chr1	15934433	Silent	NA	A2731A	0.09
STAD	chr1	15934832	Silent	rs772358107	S2864S	0.19
STAD	chr1	15934379	Silent	NA	A2713A	0.22
STAD	chr1	15876486	Missense_Mutation	novel	G230V	0.1
STAD	chr1	15935987	Silent	rs766572623	P3249P	0.65
STAD	chr1	15932890	Missense_Mutation	rs779675366	A2217V	0.13
STAD	chr1	15876221	Missense_Mutation	NA	R142C	0.18
STAD	chr1	15933970	Missense_Mutation	NA	D2577G	0.29
STAD	chr1	15929280	Missense_Mutation	rs199847404	V1014M	0.12
STAD	chr1	15872876	Silent	NA	A48A	0.24
STAD	chr1	15934638	Missense_Mutation	rs140025266	A2800T	0.09
STAD	chr1	15933719	Frame_Shift_Del	NA	*P2495Lfs4**	0.16
STAD	chr1	15932121	Missense_Mutation	rs745908478	D1961N	0.44
STAD	chr1	15935517	Missense_Mutation	novel	L3093I	0.35
STAD	chr1	15937180	Silent	NA	G3348G	0.29
STAD	chr1	15920966	Missense_Mutation	rs763959899	G578S	0.29
STAD	chr1	15929388	Frame_Shift_Del	NA	*I1052Sfs40**	0.16
STAD	chr1	15932394	Frame_Shift_Del	novel	*N2053Tfs11**	0.3
STAD	chr1	15872826	Missense_Mutation	NA	V32M	0.32
STAD	chr1	15928201	Missense_Mutation	NA	G654E	0.36
STAD	chr1	15935248	Missense_Mutation	NA	S3003L	0.41
STAD	chr1	15911261	Missense_Mutation	NA	F401L	0.26
STAD	chr1	15928129	Missense_Mutation	NA	R630H	0.53
STAD	chr1	15929018	Missense_Mutation	NA	K926N	0.29
STAD	chr1	15933925	Missense_Mutation	NA	V2562A	0.32
STAD	chr1	15938759	Silent	rs775916706	G3582G	0.26
STAD	chr1	15928288	Missense_Mutation	novel	Y683C	0.41
STAD	chr1	15929416	Missense_Mutation	novel	T1059I	0.1
STAD	chr1	15931173	Missense_Mutation	novel	V1645I	0.35
STAD	chr1	15931990	Missense_Mutation	rs780910569	R1917H	0.49
STAD	chr1	15936119	Silent	novel	V3293V	0.18
STAD	chr1	15874383	Intron	novel		0.37
STAD	chr1	15876613	Silent	rs746082766	S272S	0.47
STAD	chr1	15932449	Frame_Shift_Del	NA	*N2072Tfs14**	0.1
STAD	chr1	15937265	Missense_Mutation	NA	P3377S	0.07
STAD	chr1	15911257	Frame_Shift_Del	novel	*F401Lfs6**	0.31
STAD	chr1	15929288	Frame_Shift_Del	novel	*K1018Sfs13**	0.38
STAD	chr1	15936035	Silent	NA	G3265G	0.12
STAD	chr1	15874375	Intron	rs753096000		0.43
STAD	chr1	15928637	Silent	novel	P799P	0.65
STAD	chr1	15930202	Missense_Mutation	NA	A1321V	0.14
STAD	chr1	15932642	Silent	NA	S2134S	0.18
STAD	chr1	15930033	Nonsense_Mutation	NA	R1265*	0.04
STAD	chr1	15928344	Nonsense_Mutation	novel	R702*	0.42
STAD	chr1	15931961	Silent	novel	V1907V	0.09
STAD	chr1	15929625	Missense_Mutation	rs759801779	V1129I	0.25
STAD	chr1	15909439	Missense_Mutation	NA	S334R	0.06	RRM_5
STAD	chr1	15928533	Missense_Mutation	NA	S765C	0.09
STAD	chr1	15930154	Missense_Mutation	NA	E1305V	0.05
STAD	chr1	15932409	Missense_Mutation	NA	T2057A	0.09
STAD	chr1	15932386	Missense_Mutation	NA	G2049D	0.16
STAD	chr1	15934630	Missense_Mutation	rs779271032	P2797L	0.12
STAD	chr1	15909381	Silent	NA	A314A	0.37
STAD	chr1	15932433	Frame_Shift_Del	novel	*K2066Nfs20**	0.25
STAD	chr1	15933731	Silent	novel	K2497K	0.25
STAD	chr1	15909418	Frame_Shift_Ins	novel	*D329Rfs2**	0.07	RRM_5
STAD	chr1	15922351	Splice_Site	NA	X617_splice	0.45
STAD	chr1	15933264	Nonsense_Mutation	NA	R2342*	0.2
STAD	chr1	15935987	Silent	rs766572623	P3249P	0.25
STAD	chr1	15937645	Missense_Mutation	NA	K3503N	0.33
STAD	chr1	15930890	Missense_Mutation	NA	E1550D	0.24
STAD	chr1	15928254	Nonsense_Mutation	NA	R672*	0.52
STAD	chr1	15937344	Missense_Mutation	rs549789481	R3403H	0.18
STAD	chr1	15930591	Missense_Mutation	NA	A1451T	0.08
STAD	chr1	15873083	Silent	rs201724026	G117G	0.32
STAD	chr1	15928729	Missense_Mutation	NA	S830F	0.32
STAD	chr1	15931175	Silent	NA	V1645V	0.07
STAD	chr1	15933719	Frame_Shift_Del	NA	*P2495Lfs4**	0.33
STAD	chr1	15935278	Missense_Mutation	NA	V3013D	0.08
STAD	chr1	15934218	Missense_Mutation	NA	V2660I	0.07
STAD	chr1	15931433	Silent	novel	L1731L	0.27
STAD	chr1	15928359	In_Frame_Del	novel	E707_R713del	0.08
STAD	chr1	15929615	Silent	rs778372049	E1125E	0.15
STAD	chr1	15931067	Silent	NA	K1609K	0.33
STAD	chr1	15934160	Frame_Shift_Del	novel	*K2641Nfs11**	0.29
STAD	chr1	15939354	Missense_Mutation	rs367592589	R3641H	0.22
STAD	chr1	15931275	Missense_Mutation	rs779103344	V1679I	0.33
STAD	chr1	15937432	Silent	novel	P3432P	0.19
TGCT	chr1	15848054	5'UTR	novel		0.13
TGCT	chr1	15928223	Nonsense_Mutation	novel	W661*	0.29
THCA	chr1	15911232	Missense_Mutation	novel	A392P	0.07
THCA	chr1	15911233	Nonsense_Mutation	novel	*A392_L393insSYFF**	0.07
THCA	chr1	15929568	Missense_Mutation	novel	K1110E	0.09
THCA	chr1	15929569	Missense_Mutation	novel	K1110T	0.09
THCA	chr1	15929192	Frame_Shift_Ins	novel	*K985Afs10**	0.08
THCA	chr1	15929194	Missense_Mutation	novel	K985R	0.08
THCA	chr1	15930742	Missense_Mutation	novel	R1501K	0.03
THCA	chr1	15932639	Missense_Mutation	novel	L2133F	0.03
THCA	chr1	15932640	In_Frame_Ins	novel	S2134delinsFST	0.03
THYM	chr1	15930726	Missense_Mutation	novel	K1496Q	0.13
THYM	chr1	15930454	Frame_Shift_Ins	novel	*L1407Ffs11**	0.24
UCEC	chr1	15876292	Silent	NA	Y165Y	0.49
UCEC	chr1	15929589	Nonsense_Mutation	NA	Q1117*	0.55
UCEC	chr1	15934940	Silent	NA	S2900S	0.54
UCEC	chr1	15935659	Missense_Mutation	rs761478249	P3140L	0.73
UCEC	chr1	15936191	Silent	rs369418498	P3317P	0.47
UCEC	chr1	15940255	3'UTR	novel		0.41
UCEC	chr1	15930425	Silent	NA	A1395A	0.47
UCEC	chr1	15928128	Missense_Mutation	rs749814808	R630C	0.32
UCEC	chr1	15930827	Silent	NA	R1529R	0.33
UCEC	chr1	15934991	Silent	NA	L2917L	0.38
UCEC	chr1	15872905	Missense_Mutation	NA	S58T	0.18
UCEC	chr1	15874157	Intron	NA		0.3
UCEC	chr1	15920950	Silent	NA	T572T	0.24
UCEC	chr1	15934571	Silent	rs760916198	A2777A	0.35
UCEC	chr1	15936225	Missense_Mutation	novel	S3329P	0.35
UCEC	chr1	15937563	Missense_Mutation	NA	T3476I	0.12
UCEC	chr1	15916197	Missense_Mutation	NA	R438I	0.3
UCEC	chr1	15918931	Silent	NA	I467I	0.32
UCEC	chr1	15928206	Nonsense_Mutation	NA	E656*	0.33
UCEC	chr1	15929649	Missense_Mutation	rs138355680	R1137C	0.42
UCEC	chr1	15929940	Missense_Mutation	rs199763346	D1234N	0.29
UCEC	chr1	15932047	Missense_Mutation	novel	R1936Q	0.42
UCEC	chr1	15874326	Intron	novel		0.11
UCEC	chr1	15876311	Missense_Mutation	novel	D172N	0.42
UCEC	chr1	15930985	Missense_Mutation	novel	L1582P	0.33
UCEC	chr1	15928453	Missense_Mutation	rs777013611	G738A	0.49
UCEC	chr1	15874279	Intron	novel		0.11
UCEC	chr1	15933517	Missense_Mutation	novel	S2426Y	0.1
UCEC	chr1	15934231	Missense_Mutation	NA	P2664L	0.25
UCEC	chr1	15940227	3'UTR	novel		0.08
UCEC	chr1	15848096	Missense_Mutation	novel	V10A	0.13
UCEC	chr1	15940351	3'UTR	novel		0.31
UCEC	chr1	15920965	Silent	rs550746838	I577I	0.45
UCEC	chr1	15935286	Missense_Mutation	novel	L3016V	0.36
UCEC	chr1	15847941	5'UTR	novel		0.46
UCEC	chr1	15930681	Nonsense_Mutation	novel	E1481*	0.14
UCEC	chr1	15931408	Nonsense_Mutation	novel	S1723*	0.16
UCEC	chr1	15928098	Nonsense_Mutation	NA	R620*	0.33
UCEC	chr1	15928872	Missense_Mutation	rs763982034	V878M	0.37
UCEC	chr1	15931155	Missense_Mutation	novel	P1639S	0.39
UCEC	chr1	15933658	Missense_Mutation	novel	P2473H	0.51
UCEC	chr1	15934109	Silent	rs770853256	S2623S	0.35
UCEC	chr1	15935400	Missense_Mutation	novel	A3054T	0.44
UCEC	chr1	15911291	Missense_Mutation	novel	W411C	0.06
UCEC	chr1	15940058	3'UTR	novel		0.32
UCEC	chr1	15929388	Frame_Shift_Del	NA	*I1052Sfs40**	0.62
UCEC	chr1	15935272	Missense_Mutation	rs759881159	R3011Q	0.24
UCEC	chr1	15934991	Silent	NA	L2917L	0.22
UCEC	chr1	15933440	Silent	NA	S2400S	0.04
UCEC	chr1	15876350	Missense_Mutation	rs148074613	A185T	0.3
UCEC	chr1	15919044	Missense_Mutation	NA	R505H	0.11
UCEC	chr1	15920917	Missense_Mutation	novel	E561D	0.08
UCEC	chr1	15928356	Missense_Mutation	rs748777153	R706C	0.26
UCEC	chr1	15936167	Silent	rs773857404	G3309G	0.23
UCEC	chr1	15937949	Silent	rs780849980	I3549I	0.32
UCEC	chr1	15938789	Silent	rs773036703	T3592T	0.23
UCEC	chr1	15939657	3'UTR	novel		0.41
UCEC	chr1	15938854	Missense_Mutation	NA	V3614D	0.26
UCEC	chr1	15929729	Silent	rs775651371	I1163I	0.51
UCEC	chr1	15930293	Silent	NA	F1351F	0.5
UCEC	chr1	15931309	Missense_Mutation	NA	A1690D	0.61
UCEC	chr1	15931400	Missense_Mutation	NA	E1720D	0.33
UCEC	chr1	15932481	Nonsense_Mutation	NA	R2081*	0.35
UCEC	chr1	15934873	Missense_Mutation	rs781561009	A2878V	0.53
UCEC	chr1	15939933	3'UTR	novel		0.35
UCEC	chr1	15940160	3'UTR	novel		0.46
UCEC	chr1	15909353	Missense_Mutation	novel	S305Y	0.07	RRM_5
UCEC	chr1	15929373	Missense_Mutation	novel	L1045I	0.38
UCEC	chr1	15930448	Missense_Mutation	novel	R1403Q	0.44
UCEC	chr1	15934369	Missense_Mutation	novel	P2710Q	0.39
UCEC	chr1	15939303	Missense_Mutation	novel	Y3624C	0.3
UCEC	chr1	15931008	Missense_Mutation	novel	L1590F	0.59
UCEC	chr1	15934726	Missense_Mutation	novel	R2829Q	0.24
UCEC	chr1	15935003	Silent	rs756480556	T2921T	0.29
UCEC	chr1	15936164	Silent	rs779804838	Y3308Y	0.37
UCEC	chr1	15940249	3'UTR	rs762548080		0.45
UCEC	chr1	15936229	Missense_Mutation	novel	S3330Y	0.16
UCEC	chr1	15939997	3'UTR	novel		0.18
UCEC	chr1	15940056	3'UTR	novel		0.17
UCEC	chr1	15930529	Missense_Mutation	novel	K1430T	0.43
UCEC	chr1	15933703	Missense_Mutation	novel	G2488V	0.17
UCEC	chr1	15872981	Silent	novel	T83T	0.35
UCEC	chr1	15876323	Missense_Mutation	rs749739850	R176W	0.21
UCEC	chr1	15931173	Missense_Mutation	novel	V1645I	0.28
UCEC	chr1	15931381	Missense_Mutation	novel	M1714T	0.36
UCEC	chr1	15934347	Missense_Mutation	novel	P2703T	0.5
UCEC	chr1	15876609	Missense_Mutation	NA	G271D	0.64
UCEC	chr1	15928291	Missense_Mutation	novel	R684M	0.5
UCEC	chr1	15928438	Missense_Mutation	rs779692614	R733H	0.59
UCEC	chr1	15932920	Missense_Mutation	novel	S2227Y	0.63
UCEC	chr1	15934036	Missense_Mutation	rs753076589	S2599L	0.5
UCEC	chr1	15937912	Missense_Mutation	novel	S3537Y	0.54
UCEC	chr1	15911115	Missense_Mutation	novel	D353N	0.09	RRM_5
UCEC	chr1	15928150	Missense_Mutation	rs149954308	R637Q	0.32
UCEC	chr1	15876430	Silent	NA	L211L	0.48
UCEC	chr1	15934063	Frame_Shift_Del	NA	*K2609Rfs29**	0.41
UCEC	chr1	15928416	Frame_Shift_Ins	NA	*S727Kfs24**	0.43
UCEC	chr1	15929854	Missense_Mutation	NA	R1205H	0.09
UCEC	chr1	15876209	Missense_Mutation	novel	D138Y	0.35
UCEC	chr1	15918940	Missense_Mutation	novel	K470N	0.15
UCEC	chr1	15922342	Missense_Mutation	rs767352538	E615K	0.33
UCEC	chr1	15933934	Missense_Mutation	NA	A2565V	0.47
UCEC	chr1	15874267	Intron	novel		0.29
UCEC	chr1	15911270	Missense_Mutation	novel	M404I	0.34
UCEC	chr1	15937917	Missense_Mutation	rs751381292	P3539S	0.36
UCEC	chr1	15928591	Missense_Mutation	rs181758065	R784H	0.78
UCEC	chr1	15928785	Frame_Shift_Ins	novel	*P851Afs5**	0.44
UCEC	chr1	15929115	Missense_Mutation	novel	K959E	0.52
UCEC	chr1	15928411	Missense_Mutation	novel	R724Q	0.15
UCEC	chr1	15933198	Nonsense_Mutation	novel	E2320*	0.21
UCEC	chr1	15935635	Missense_Mutation	novel	R3132K	0.45
UCEC	chr1	15931912	Missense_Mutation	novel	E1891A	0.5
UCEC	chr1	15932412	Missense_Mutation	rs200349060	A2058T	0.46
UCEC	chr1	15932548	Frame_Shift_Del	novel	*A2105Lfs33**	0.17
UCEC	chr1	15929586	Silent	NA	L1116L	0.39
UCEC	chr1	15919472	Missense_Mutation	novel	D530E	0.41
UCEC	chr1	15933472	Missense_Mutation	novel	S2411L	0.34
UCEC	chr1	15933472	Missense_Mutation	novel	S2411L	0.39
UCEC	chr1	15934342	Missense_Mutation	novel	T2701M	0.3
UCEC	chr1	15935600	Silent	novel	P3120P	0.32
UCEC	chr1	15939973	3'UTR	novel		0.25
UCEC	chr1	15874162	Intron	novel		0.43
UCEC	chr1	15930477	Missense_Mutation	novel	D1413Y	0.62
UCEC	chr1	15940160	3'UTR	novel		0.57
UCEC	chr1	15940159	3'UTR	novel		0.41
UCEC	chr1	15919509	Missense_Mutation	novel	V543M	0.07
UCEC	chr1	15930166	Missense_Mutation	NA	F1309C	0.23
UCEC	chr1	15930703	Missense_Mutation	NA	R1488I	0.19
UCEC	chr1	15932269	Missense_Mutation	rs530603850	R2010H	0.22
UCEC	chr1	15929951	Silent	novel	I1237I	0.57
UCEC	chr1	15930187	Missense_Mutation	novel	R1316K	0.38
UCEC	chr1	15931017	Missense_Mutation	novel	M1593V	0.38
UCEC	chr1	15932713	Missense_Mutation	rs144493499	P2158L	0.41
UCEC	chr1	15932714	Silent	rs778641327	P2158P	0.37
UCEC	chr1	15873114	Missense_Mutation	rs751080105	R128C	0.29
UCEC	chr1	15940278	3'UTR	novel		0.35
UCEC	chr1	15933447	Missense_Mutation	novel	S2403R	0.32
UCEC	chr1	15932184	Missense_Mutation	NA	R1982W	0.31
UCEC	chr1	15934468	Missense_Mutation	rs140026416	A2743V	0.1
UCEC	chr1	15934570	Missense_Mutation	rs181891870	A2777V	0.1
UCEC	chr1	15932848	Missense_Mutation	novel	R2203M	0.29
UCEC	chr1	15934517	Silent	rs200775617	T2759T	0.32
UCEC	chr1	15939675	3'UTR	rs189311173		0.39
UCEC	chr1	15932240	Frame_Shift_Del	novel	*N2002Mfs20**	0.33
UCEC	chr1	15931584	Missense_Mutation	novel	D1782Y	0.03
UCEC	chr1	15939973	3'UTR	novel		0.56
UCEC	chr1	15929421	Missense_Mutation	NA	A1061T	0.05
UCEC	chr1	15930336	Nonsense_Mutation	NA	R1366*	0.45
UCEC	chr1	15930541	Missense_Mutation	NA	F1434S	0.41
UCEC	chr1	15909361	Nonsense_Mutation	NA	R308*	0.24	RRM_5
UCEC	chr1	15929199	Missense_Mutation	rs376676096	R987C	0.28
UCEC	chr1	15933480	Nonsense_Mutation	NA	E2414*	0.26
UCEC	chr1	15932399	Frame_Shift_Del	NA	*P2055Lfs9**	0.35
UCEC	chr1	15928871	Silent	rs762589812	C877C	0.41
UCEC	chr1	15936109	Missense_Mutation	NA	T3290I	0.57
UCEC	chr1	15911261	Missense_Mutation	NA	F401L	0.4
UCEC	chr1	15930965	Silent	NA	S1575S	0.35
UCEC	chr1	15937437	Frame_Shift_Del	novel	*P3434Rfs8**	0.15
UCEC	chr1	15934094	Missense_Mutation	NA	I2618M	0.32
UCEC	chr1	15873115	Missense_Mutation	NA	R128H	0.35
UCEC	chr1	15876292	Silent	NA	Y165Y	0.57
UCEC	chr1	15876464	Missense_Mutation	novel	D223N	0.27
UCEC	chr1	15930255	Missense_Mutation	rs760134992	R1339C	0.45
UCEC	chr1	15931979	Silent	rs372374019	D1913D	0.29
UCEC	chr1	15935331	Missense_Mutation	novel	P3031A	0.22
UCEC	chr1	15936254	Missense_Mutation	novel	K3338N	0.41
UCEC	chr1	15940377	3'UTR	novel		0.54
UCEC	chr1	15876324	Missense_Mutation	NA	R176L	0.37
UCEC	chr1	15920926	Silent	NA	Y564Y	0.25
UCEC	chr1	15929074	Missense_Mutation	novel	L945R	0.29
UCEC	chr1	15916213	Silent	NA	G443G	0.29
UCEC	chr1	15918994	Silent	rs756045251	S488S	0.45
UCEC	chr1	15928434	Nonsense_Mutation	NA	R732*	0.48
UCEC	chr1	15930731	Missense_Mutation	novel	K1497N	0.38
UCEC	chr1	15931510	Missense_Mutation	novel	Q1757R	0.38
UCEC	chr1	15939831	3'UTR	novel		0.47
UCEC	chr1	15873124	Missense_Mutation	novel	R131Q	0.28
UCEC	chr1	15876567	Missense_Mutation	novel	R257I	0.38
UCEC	chr1	15931480	Missense_Mutation	rs768562805	S1747N	0.23
UCEC	chr1	15939973	3'UTR	novel		0.26
UCS	chr1	15876470	Frame_Shift_Del	novel	*T225Rfs22**	0.35

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BRCA	DEL	0.3667	1.4923e-44
CESC	DEL	0.0983	0.00029523
CHOL	DEL	0.8056	3.3987e-23
DLBC	DEL	0.1042	0.011841
HNSC	DEL	0.1437	7.0766e-07
KIRC	DEL	0.1439	2.3538e-09
KIRP	DEL	0.1771	1.462e-09
LUAD	DEL	0.1512	0.0024765
LUSC	DEL	0.3633	2.5882e-07
MESO	DEL	0.3333	2.434e-07
READ	DEL	0.3939	2.1758e-10
TGCT	DEL	0.1867	0.00046313
UCS	DEL	0.2679	0.0051125

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.026	Kaplan-Meier Survival Analysis
SARC	0.0066	Kaplan-Meier Survival Analysis
ACC	0.021	Kaplan-Meier Survival Analysis
ESCA	0.022	Kaplan-Meier Survival Analysis
READ	0.029	Kaplan-Meier Survival Analysis
LIHC	0.018	Kaplan-Meier Survival Analysis
OV	0.0011	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000065526 (Gene tree)
Gene ID: 23013
Gene Symbol: SPEN
Alias: KIAA0929|MINT|SHARP|RBM15C
Full Name: spen family transcriptional repressor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 92,597 bases
Position: chr1:15,847,864-15,940,460
Accession: 17575
RBP type: canonical RBP
Summary: This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000364912	RRM_5	PF13893.6	1e-06	1	2
ENSP00000364912	RRM_5	PF13893.6	1e-06	2	2
ENSP00000364912	RRM_1	PF00076.22	5.5e-43	1	4
ENSP00000364912	RRM_1	PF00076.22	5.5e-43	2	4
ENSP00000364912	RRM_1	PF00076.22	5.5e-43	3	4
ENSP00000364912	RRM_1	PF00076.22	5.5e-43	4	4
ENSP00000400914	RRM_1	PF00076.22	1.3e-25	1	2
ENSP00000400914	RRM_1	PF00076.22	1.3e-25	2	2
ENSP00000388021	RRM_1	PF00076.22	1.5e-05	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
26190105	A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing.	Cell Rep	2015 Jul 28	Moindrot B	doi: 10.1016/j.celrep.2015.06.053
11331609	Sharp, an inducible cofactor that integrates nuclear receptor repression and activation.	Genes Dev	2001 May 1	Shi Y	-
24748666	The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs.	Nucleic Acids Res	2014 Jun	Arieti F	doi: 10.1093/nar/gku277
28835257	Long noncoding RNAs coordinate functions between mitochondria and the nucleus.	Epigenetics Chromatin	2017 Aug 23	Dong Y	doi: 10.1186/s13072-017-0149-x.
8034589	Multiple sets of basal factors initiate transcription by RNA polymerase II.	J Biol Chem	1994 Jul 15	Parvin JD	-
17959829	Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.	Mol Biol Cell	2008 Jan	Shrivastava-Ranjan P	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000442985	SPEN-203	891	-	ENSP00000400914	297 (aa)	-	H0Y5U7
ENST00000375759	SPEN-201	12232	-	ENSP00000364912	3664 (aa)	-	Q96T58
ENST00000438066	SPEN-202	1733	-	ENSP00000388021	373 (aa)	-	F6WRY4
ENST00000487496	SPEN-205	543	-	-	- (aa)	-	-
ENST00000471538	SPEN-204	1404	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000065526's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000065526	Heart Failure	4.9030685E-004	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000065526	rs6701290	1	15862186	G	Heel bone mineral density	28869591	[0.032-0.064] unit increase	0.0476853	EFO_0009270
ENSG00000065526	rs6701290	1	15862186	G	Heel bone mineral density	28869591	[0.032-0.053] unit increase	0.0425317	EFO_0009270
ENSG00000065526	rs6701290	1	15862186	G	Heel bone mineral density	28869591	[0.024-0.053] unit increase	0.0382322	EFO_0009270
ENSG00000065526	rs6701290	1	15862186	?	Heel bone mineral density	30048462	[0.032-0.045] unit increase	0.0386526	EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000065526's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000065526	SPEN	85	91.667	ENSAPOG00000009853	-	90	75.094	Acanthochromis_polyacanthus
ENSG00000065526	SPEN	85	85.259	ENSAPOG00000011411	si:ch1073-335m2.2	75	83.041	Acanthochromis_polyacanthus
ENSG00000065526	SPEN	99	99.663	ENSAMEG00000011817	SPEN	100	88.250	Ailuropoda_melanoleuca
ENSG00000065526	SPEN	78	88.362	ENSAOCG00000008077	si:ch1073-335m2.2	82	77.037	Amphiprion_ocellaris
ENSG00000065526	SPEN	85	92.063	ENSAOCG00000014505	-	89	49.240	Amphiprion_ocellaris
ENSG00000065526	SPEN	85	92.063	ENSAPEG00000010288	-	89	49.281	Amphiprion_percula
ENSG00000065526	SPEN	85	85.259	ENSAPEG00000013515	si:ch1073-335m2.2	82	83.041	Amphiprion_percula
ENSG00000065526	SPEN	96	82.584	ENSATEG00000005627	-	90	49.632	Anabas_testudineus
ENSG00000065526	SPEN	85	85.771	ENSATEG00000007674	si:ch1073-335m2.2	75	84.024	Anabas_testudineus
ENSG00000065526	SPEN	85	89.723	ENSACAG00000013761	SPEN	100	63.856	Anolis_carolinensis
ENSG00000065526	SPEN	99	99.327	ENSANAG00000034428	SPEN	99	95.935	Aotus_nancymaae
ENSG00000065526	SPEN	85	85.657	ENSACLG00000021433	si:ch1073-335m2.2	75	83.626	Astatotilapia_calliptera
ENSG00000065526	SPEN	85	90.476	ENSACLG00000016922	-	92	48.330	Astatotilapia_calliptera
ENSG00000065526	SPEN	85	92.460	ENSAMXG00000012485	spen	89	82.065	Astyanax_mexicanus
ENSG00000065526	SPEN	99	98.990	ENSBTAG00000018729	SPEN	100	87.208	Bos_taurus
ENSG00000065526	SPEN	99	99.327	ENSCJAG00000008527	SPEN	100	95.382	Callithrix_jacchus
ENSG00000065526	SPEN	99	99.663	ENSCAFG00000016132	-	96	92.476	Canis_familiaris
ENSG00000065526	SPEN	99	99.327	ENSCHIG00000025070	SPEN	100	87.317	Capra_hircus
ENSG00000065526	SPEN	89	99.240	ENSTSYG00000036016	SPEN	99	89.917	Carlito_syrichta
ENSG00000065526	SPEN	99	97.980	ENSCAPG00000013803	SPEN	100	81.846	Cavia_aperea
ENSG00000065526	SPEN	99	97.980	ENSCPOG00000014036	SPEN	100	82.155	Cavia_porcellus
ENSG00000065526	SPEN	100	91.154	ENSCCAG00000020258	SPEN	99	95.191	Cebus_capucinus
ENSG00000065526	SPEN	99	99.663	ENSCATG00000015079	SPEN	100	99.265	Cercocebus_atys
ENSG00000065526	SPEN	99	98.316	ENSCLAG00000002018	SPEN	99	89.589	Chinchilla_lanigera
ENSG00000065526	SPEN	99	99.663	ENSCSAG00000000841	SPEN	100	97.441	Chlorocebus_sabaeus
ENSG00000065526	SPEN	99	96.633	ENSCPBG00000010477	SPEN	100	72.257	Chrysemys_picta_bellii
ENSG00000065526	SPEN	96	99.301	ENSCANG00000034547	SPEN	99	95.609	Colobus_angolensis_palliatus
ENSG00000065526	SPEN	99	97.980	ENSCGRG00001007725	Spen	100	81.942	Cricetulus_griseus_chok1gshd
ENSG00000065526	SPEN	99	96.970	ENSCGRG00000010581	Spen	100	80.738	Cricetulus_griseus_crigri
ENSG00000065526	SPEN	85	91.667	ENSCSEG00000003915	-	91	47.902	Cynoglossus_semilaevis
ENSG00000065526	SPEN	85	90.079	ENSCVAG00000016346	-	90	48.091	Cyprinodon_variegatus
ENSG00000065526	SPEN	85	81.275	ENSCVAG00000009075	si:ch1073-335m2.2	76	84.211	Cyprinodon_variegatus
ENSG00000065526	SPEN	85	85.259	ENSDARG00000074332	si:ch1073-335m2.2	79	62.205	Danio_rerio
ENSG00000065526	SPEN	85	91.667	ENSDARG00000074245	spen	100	88.889	Danio_rerio
ENSG00000065526	SPEN	99	98.333	ENSDNOG00000041948	SPEN	100	87.219	Dasypus_novemcinctus
ENSG00000065526	SPEN	96	98.955	ENSDORG00000023909	Spen	99	80.295	Dipodomys_ordii
ENSG00000065526	SPEN	67	97.059	ENSETEG00000016692	-	67	97.059	Echinops_telfairi
ENSG00000065526	SPEN	99	98.653	ENSEASG00005015911	SPEN	99	100.000	Equus_asinus_asinus
ENSG00000065526	SPEN	99	98.653	ENSECAG00000008833	SPEN	99	100.000	Equus_caballus
ENSG00000065526	SPEN	99	83.502	ENSEEUG00000010255	SPEN	76	95.349	Erinaceus_europaeus
ENSG00000065526	SPEN	85	84.921	ENSELUG00000007726	si:ch1073-335m2.2	77	80.556	Esox_lucius
ENSG00000065526	SPEN	99	97.643	ENSFDAG00000010212	SPEN	100	83.119	Fukomys_damarensis
ENSG00000065526	SPEN	85	80.478	ENSFHEG00000004544	si:ch1073-335m2.2	77	73.430	Fundulus_heteroclitus
ENSG00000065526	SPEN	85	84.861	ENSGMOG00000008156	si:ch1073-335m2.2	66	79.888	Gadus_morhua
ENSG00000065526	SPEN	85	90.079	ENSGMOG00000008397	-	88	65.726	Gadus_morhua
ENSG00000065526	SPEN	85	90.476	ENSGAFG00000015819	-	90	74.340	Gambusia_affinis
ENSG00000065526	SPEN	85	81.349	ENSGAFG00000021570	si:ch1073-335m2.2	77	83.432	Gambusia_affinis
ENSG00000065526	SPEN	85	85.657	ENSGACG00000001176	si:ch1073-335m2.2	78	80.588	Gasterosteus_aculeatus
ENSG00000065526	SPEN	85	90.873	ENSGACG00000005341	-	99	46.885	Gasterosteus_aculeatus
ENSG00000065526	SPEN	99	96.633	ENSGAGG00000020785	SPEN	100	72.841	Gopherus_agassizii
ENSG00000065526	SPEN	100	99.154	ENSGGOG00000012041	SPEN	100	99.154	Gorilla_gorilla
ENSG00000065526	SPEN	96	81.461	ENSHBUG00000020626	-	93	48.330	Haplochromis_burtoni
ENSG00000065526	SPEN	85	85.657	ENSHBUG00000023253	si:ch1073-335m2.2	75	83.626	Haplochromis_burtoni
ENSG00000065526	SPEN	99	97.643	ENSHGLG00000019259	SPEN	100	81.927	Heterocephalus_glaber_female
ENSG00000065526	SPEN	99	97.306	ENSHGLG00100019294	SPEN	95	86.279	Heterocephalus_glaber_male
ENSG00000065526	SPEN	85	82.869	ENSHCOG00000006004	si:ch1073-335m2.2	73	80.469	Hippocampus_comes
ENSG00000065526	SPEN	85	85.657	ENSIPUG00000018212	si:ch1073-335m2.2	87	77.273	Ictalurus_punctatus
ENSG00000065526	SPEN	96	82.778	ENSIPUG00000021668	spen	88	81.967	Ictalurus_punctatus
ENSG00000065526	SPEN	99	99.327	ENSSTOG00000021428	SPEN	100	87.185	Ictidomys_tridecemlineatus
ENSG00000065526	SPEN	99	98.653	ENSJJAG00000010882	Spen	100	83.396	Jaculus_jaculus
ENSG00000065526	SPEN	85	90.476	ENSKMAG00000003882	-	89	48.272	Kryptolebias_marmoratus
ENSG00000065526	SPEN	85	82.470	ENSKMAG00000021725	si:ch1073-335m2.2	65	82.456	Kryptolebias_marmoratus
ENSG00000065526	SPEN	85	84.462	ENSLBEG00000020855	si:ch1073-335m2.2	72	72.000	Labrus_bergylta
ENSG00000065526	SPEN	83	40.641	ENSLBEG00000019129	-	89	40.518	Labrus_bergylta
ENSG00000065526	SPEN	85	94.422	ENSLACG00000003258	SPEN	99	63.264	Latimeria_chalumnae
ENSG00000065526	SPEN	99	97.980	ENSLAFG00000004524	SPEN	100	87.289	Loxodonta_africana
ENSG00000065526	SPEN	99	99.663	ENSMFAG00000041974	SPEN	100	97.522	Macaca_fascicularis
ENSG00000065526	SPEN	99	99.663	ENSMMUG00000008026	SPEN	100	97.763	Macaca_mulatta
ENSG00000065526	SPEN	99	99.663	ENSMNEG00000042402	SPEN	100	97.577	Macaca_nemestrina
ENSG00000065526	SPEN	99	99.663	ENSMLEG00000039293	SPEN	99	97.196	Mandrillus_leucophaeus
ENSG00000065526	SPEN	85	85.657	ENSMAMG00000023870	si:ch1073-335m2.2	85	83.234	Mastacembelus_armatus
ENSG00000065526	SPEN	85	85.657	ENSMZEG00005011762	si:ch1073-335m2.2	75	83.626	Maylandia_zebra
ENSG00000065526	SPEN	99	96.296	ENSMGAG00000005180	-	100	96.633	Meleagris_gallopavo
ENSG00000065526	SPEN	99	98.316	ENSMAUG00000008318	Spen	99	83.896	Mesocricetus_auratus
ENSG00000065526	SPEN	99	99.327	ENSMICG00000030994	SPEN	100	90.479	Microcebus_murinus
ENSG00000065526	SPEN	99	97.306	ENSMOCG00000016083	Spen	100	82.149	Microtus_ochrogaster
ENSG00000065526	SPEN	85	85.657	ENSMMOG00000021742	si:ch1073-335m2.2	58	79.888	Mola_mola
ENSG00000065526	SPEN	85	94.048	ENSMODG00000003411	SPEN	100	71.014	Monodelphis_domestica
ENSG00000065526	SPEN	84	91.129	ENSMALG00000008625	-	90	48.985	Monopterus_albus
ENSG00000065526	SPEN	99	97.643	MGP_CAROLIEiJ_G0026745	Spen	100	80.739	Mus_caroli
ENSG00000065526	SPEN	99	96.990	ENSMUSG00000040761	Spen	100	80.445	Mus_musculus
ENSG00000065526	SPEN	99	97.306	MGP_PahariEiJ_G0029076	Spen	100	80.119	Mus_pahari
ENSG00000065526	SPEN	99	97.643	MGP_SPRETEiJ_G0027724	Spen	100	80.699	Mus_spretus
ENSG00000065526	SPEN	99	98.653	ENSMPUG00000016317	SPEN	100	87.410	Mustela_putorius_furo
ENSG00000065526	SPEN	99	96.990	ENSMLUG00000010144	SPEN	97	96.774	Myotis_lucifugus
ENSG00000065526	SPEN	99	98.653	ENSNGAG00000000641	Spen	95	85.326	Nannospalax_galili
ENSG00000065526	SPEN	85	85.657	ENSNBRG00000005733	si:ch1073-335m2.2	70	83.626	Neolamprologus_brichardi
ENSG00000065526	SPEN	99	99.663	ENSNLEG00000007652	SPEN	99	98.026	Nomascus_leucogenys
ENSG00000065526	SPEN	87	93.750	ENSMEUG00000002422	SPEN	91	93.750	Notamacropus_eugenii
ENSG00000065526	SPEN	99	98.316	ENSOPRG00000015800	SPEN	93	90.441	Ochotona_princeps
ENSG00000065526	SPEN	100	80.785	ENSODEG00000016644	SPEN	100	80.612	Octodon_degus
ENSG00000065526	SPEN	85	90.476	ENSONIG00000006573	-	99	81.273	Oreochromis_niloticus
ENSG00000065526	SPEN	99	96.970	ENSOANG00000004165	-	100	94.828	Ornithorhynchus_anatinus
ENSG00000065526	SPEN	99	97.667	ENSOCUG00000010840	SPEN	99	83.009	Oryctolagus_cuniculus
ENSG00000065526	SPEN	71	75.743	ENSORLG00000028894	-	85	76.650	Oryzias_latipes
ENSG00000065526	SPEN	85	85.259	ENSORLG00000018414	si:ch1073-335m2.2	77	68.037	Oryzias_latipes
ENSG00000065526	SPEN	85	85.259	ENSORLG00020009351	si:ch1073-335m2.2	86	68.037	Oryzias_latipes_hni
ENSG00000065526	SPEN	71	75.743	ENSORLG00020007735	-	85	76.650	Oryzias_latipes_hni
ENSG00000065526	SPEN	99	89.189	ENSORLG00015022085	-	67	76.650	Oryzias_latipes_hsok
ENSG00000065526	SPEN	85	85.259	ENSORLG00015005537	si:ch1073-335m2.2	77	64.135	Oryzias_latipes_hsok
ENSG00000065526	SPEN	85	90.476	ENSOMEG00000007639	-	71	76.119	Oryzias_melastigma
ENSG00000065526	SPEN	85	85.259	ENSOMEG00000004509	si:ch1073-335m2.2	78	66.957	Oryzias_melastigma
ENSG00000065526	SPEN	99	98.990	ENSOGAG00000025110	SPEN	100	89.704	Otolemur_garnettii
ENSG00000065526	SPEN	99	98.333	ENSOARG00000008477	SPEN	99	86.511	Ovis_aries
ENSG00000065526	SPEN	99	99.505	ENSPPAG00000035690	SPEN	100	99.505	Pan_paniscus
ENSG00000065526	SPEN	100	99.481	ENSPTRG00000000210	SPEN	100	99.481	Pan_troglodytes
ENSG00000065526	SPEN	99	99.663	ENSPANG00000006293	SPEN	100	96.453	Papio_anubis
ENSG00000065526	SPEN	85	91.270	ENSPKIG00000002617	SPEN	93	83.511	Paramormyrops_kingsleyae
ENSG00000065526	SPEN	94	100.000	ENSPKIG00000010492	si:ch1073-335m2.2	98	100.000	Paramormyrops_kingsleyae
ENSG00000065526	SPEN	85	86.166	ENSPSIG00000008026	SPEN	100	69.345	Pelodiscus_sinensis
ENSG00000065526	SPEN	99	97.643	ENSPEMG00000022997	Spen	100	82.157	Peromyscus_maniculatus_bairdii
ENSG00000065526	SPEN	85	81.349	ENSPFOG00000017986	si:ch1073-335m2.2	76	84.615	Poecilia_formosa
ENSG00000065526	SPEN	81	91.286	ENSPFOG00000024806	-	99	81.387	Poecilia_formosa
ENSG00000065526	SPEN	85	81.349	ENSPLAG00000016625	si:ch1073-335m2.2	76	84.615	Poecilia_latipinna
ENSG00000065526	SPEN	85	90.476	ENSPMEG00000006764	-	90	74.340	Poecilia_mexicana
ENSG00000065526	SPEN	85	81.349	ENSPMEG00000002674	si:ch1073-335m2.2	76	84.615	Poecilia_mexicana
ENSG00000065526	SPEN	85	81.349	ENSPREG00000005357	si:ch1073-335m2.2	85	84.615	Poecilia_reticulata
ENSG00000065526	SPEN	85	90.476	ENSPREG00000010399	-	90	74.717	Poecilia_reticulata
ENSG00000065526	SPEN	100	99.045	ENSPPYG00000001834	SPEN	100	99.045	Pongo_abelii
ENSG00000065526	SPEN	99	97.643	ENSPCAG00000009543	SPEN	92	86.728	Procavia_capensis
ENSG00000065526	SPEN	99	99.327	ENSPCOG00000021735	SPEN	100	90.022	Propithecus_coquereli
ENSG00000065526	SPEN	99	99.327	ENSPVAG00000013794	SPEN	84	95.516	Pteropus_vampyrus
ENSG00000065526	SPEN	85	90.476	ENSPNYG00000012379	-	92	48.267	Pundamilia_nyererei
ENSG00000065526	SPEN	85	85.657	ENSPNYG00000009042	si:ch1073-335m2.2	75	83.626	Pundamilia_nyererei
ENSG00000065526	SPEN	96	84.181	ENSPNAG00000020795	spen	89	82.967	Pygocentrus_nattereri
ENSG00000065526	SPEN	85	84.462	ENSPNAG00000011452	si:ch1073-335m2.2	85	71.359	Pygocentrus_nattereri
ENSG00000065526	SPEN	99	97.643	ENSRNOG00000033556	Spen	100	80.433	Rattus_norvegicus
ENSG00000065526	SPEN	99	99.663	ENSRBIG00000039654	SPEN	100	97.086	Rhinopithecus_bieti
ENSG00000065526	SPEN	99	99.663	ENSRROG00000035686	SPEN	100	97.171	Rhinopithecus_roxellana
ENSG00000065526	SPEN	99	99.327	ENSSBOG00000028770	SPEN	91	95.647	Saimiri_boliviensis_boliviensis
ENSG00000065526	SPEN	85	94.048	ENSSHAG00000004960	SPEN	99	93.182	Sarcophilus_harrisii
ENSG00000065526	SPEN	84	65.741	ENSSFOG00015007131	si:ch1073-335m2.2	96	65.741	Scleropages_formosus
ENSG00000065526	SPEN	85	92.460	ENSSFOG00015010267	si:ch1073-335m2.2	88	83.684	Scleropages_formosus
ENSG00000065526	SPEN	96	82.022	ENSSMAG00000008996	-	90	48.841	Scophthalmus_maximus
ENSG00000065526	SPEN	85	85.317	ENSSMAG00000000125	si:ch1073-335m2.2	86	73.077	Scophthalmus_maximus
ENSG00000065526	SPEN	88	83.041	ENSSDUG00000008416	si:ch1073-335m2.2	75	83.041	Seriola_dumerili
ENSG00000065526	SPEN	85	91.667	ENSSDUG00000003476	-	90	76.030	Seriola_dumerili
ENSG00000065526	SPEN	85	85.259	ENSSLDG00000023347	si:ch1073-335m2.2	76	83.041	Seriola_lalandi_dorsalis
ENSG00000065526	SPEN	85	91.667	ENSSLDG00000012950	-	90	76.030	Seriola_lalandi_dorsalis
ENSG00000065526	SPEN	86	66.508	ENSSPUG00000001866	-	100	66.435	Sphenodon_punctatus
ENSG00000065526	SPEN	84	84.274	ENSSPAG00000012454	si:ch1073-335m2.2	85	83.626	Stegastes_partitus
ENSG00000065526	SPEN	85	91.667	ENSSPAG00000006014	-	90	75.472	Stegastes_partitus
ENSG00000065526	SPEN	99	99.663	ENSSSCG00000034484	SPEN	99	87.945	Sus_scrofa
ENSG00000065526	SPEN	99	95.608	ENSTGUG00000002064	-	84	96.371	Taeniopygia_guttata
ENSG00000065526	SPEN	85	91.270	ENSTRUG00000024350	-	90	48.366	Takifugu_rubripes
ENSG00000065526	SPEN	52	86.364	ENSTRUG00000021008	si:ch1073-335m2.2	65	79.661	Takifugu_rubripes
ENSG00000065526	SPEN	85	85.657	ENSTNIG00000014666	si:ch1073-335m2.2	85	81.871	Tetraodon_nigroviridis
ENSG00000065526	SPEN	85	90.873	ENSTNIG00000010907	-	90	77.682	Tetraodon_nigroviridis
ENSG00000065526	SPEN	80	99.163	ENSTBEG00000003628	SPEN	77	94.393	Tupaia_belangeri
ENSG00000065526	SPEN	99	97.306	ENSTTRG00000015704	SPEN	79	95.349	Tursiops_truncatus
ENSG00000065526	SPEN	99	99.663	ENSUAMG00000009600	SPEN	100	88.390	Ursus_americanus
ENSG00000065526	SPEN	99	99.663	ENSUMAG00000021641	SPEN	100	86.874	Ursus_maritimus
ENSG00000065526	SPEN	99	99.663	ENSVVUG00000028951	SPEN	99	100.000	Vulpes_vulpes
ENSG00000065526	SPEN	97	56.421	ENSXETG00000023114	SPEN	99	56.652	Xenopus_tropicalis
ENSG00000065526	SPEN	72	83.432	ENSXCOG00000004516	si:ch1073-335m2.2	77	83.432	Xiphophorus_couchianus
ENSG00000065526	SPEN	85	80.080	ENSXMAG00000029887	si:ch1073-335m2.2	77	83.432	Xiphophorus_maculatus
ENSG00000065526	SPEN	85	90.476	ENSXMAG00000021384	-	90	72.453	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	16287852.	IDA	Process
GO:0001085	RNA polymerase II transcription factor binding	16287852.	IPI	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003714	transcription corepressor activity	16287852.	IDA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	16129689.16287852.17474147.21102556.24268649.25609649.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0007219	Notch signaling pathway	-	IEA	Process
GO:0016032	viral process	-	IEA	Process
GO:0017053	transcriptional repressor complex	16287852.	IDA	Component
GO:0045892	negative regulation of transcription, DNA-templated	16129689.	IDA	Process
GO:0050769	positive regulation of neurogenesis	16287852.	IMP	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.