EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr9	2837277	Missense_Mutation	novel	K69N	0.55
BLCA	chr9	2838476	Missense_Mutation	novel	G11E	0.33
BLCA	chr9	2824754	Missense_Mutation	rs774148520	R366K	0.15
BLCA	chr9	2804299	3'UTR	novel		0.37
BLCA	chr9	2834034	Missense_Mutation	novel	R146K	1
BLCA	chr9	2838508	5'UTR	rs559671705		0.25
BLCA	chr9	2837350	Missense_Mutation	NA	G45E	0.19
BRCA	chr9	2811363	Missense_Mutation	NA	E545Q	0.39	CPL
BRCA	chr9	2812326	Missense_Mutation	NA	K436Q	0.77	CPL
BRCA	chr9	2837402	Splice_Site	NA	X28_splice	0.23
BRCA	chr9	2829837	Silent	novel	A263A	0.06
BRCA	chr9	2811570	Missense_Mutation	rs551241677	E476K	0.27	CPL
BRCA	chr9	2823817	Silent	novel	V384V	0.1
BRCA	chr9	2830995	Missense_Mutation	rs755791650	S215L	0.15
BRCA	chr9	2812275	Missense_Mutation	rs760052993	H453D	0.22	CPL
CESC	chr9	2837402	Splice_Site	NA	X28_splice	0.17
CESC	chr9	2830977	Missense_Mutation	NA	K221R	0.5
CESC	chr9	2823795	Missense_Mutation	NA	E392Q	0.16
CESC	chr9	2844125	5'UTR	novel		0.53
CESC	chr9	2831026	Missense_Mutation	novel	D205N	0.49
CESC	chr9	2804207	3'UTR	novel		0.85
COAD	chr9	2829936	Silent	NA	Q230Q	0.32
COAD	chr9	2824764	Frame_Shift_Ins	rs777614441	*D363Tfs21**	0.48
COAD	chr9	2828698	Silent	novel	Q311Q	0.09
COAD	chr9	2811476	Missense_Mutation	rs142006198	A507V	0.16	CPL
COAD	chr9	2824723	Silent	rs778115502	T376T	0.44
COAD	chr9	2811476	Missense_Mutation	rs142006198	A507V	0.31	CPL
COAD	chr9	2804235	3'UTR	novel		0.26
COAD	chr9	2831319	Missense_Mutation	NA	R181H	0.24
COAD	chr9	2804343	Frame_Shift_Del	novel	*K645Nfs2**	0.05
COAD	chr9	2810409	Missense_Mutation	novel	A553V	0.05	CPL
COAD	chr9	2844133	5'UTR	novel		0.63
COAD	chr9	2837291	Missense_Mutation	novel	V65I	0.3
COAD	chr9	2834098	Nonsense_Mutation	novel	Q125*	0.05
COAD	chr9	2807853	Missense_Mutation	NA	S592C	0.25
COAD	chr9	2831282	Silent	novel	E193E	0.11
COAD	chr9	2820069	Silent	rs200209679	A406A	0.33
COAD	chr9	2827092	Missense_Mutation	NA	A339E	0.17
COAD	chr9	2831296	Missense_Mutation	NA	Y189H	0.17
COAD	chr9	2831284	Missense_Mutation	NA	E193K	0.21
COAD	chr9	2812291	Silent	novel	S447S	0.04
ESCA	chr9	2829813	Silent	novel	L271L	0.12
ESCA	chr9	2834111	Silent	novel	L120L	0.18
ESCA	chr9	2837324	Missense_Mutation	novel	E54K	0.23
ESCA	chr9	2834090	Silent	novel	S127S	0.17
ESCA	chr9	2844045	Splice_Region	novel		0.09
GBM	chr9	2824790	In_Frame_Del	novel	I351_A354del	0.08
GBM	chr9	2812220	Missense_Mutation	novel	S471I	0.22	CPL
GBM	chr9	2811564	Missense_Mutation	rs761766869	R478C	0.09	CPL
GBM	chr9	2804323	3'UTR	novel		0.22
KIRC	chr9	2807851	Missense_Mutation	NA	W593R	0.28
LAML	chr9	2810421	Missense_Mutation	novel	A549V	0.07	CPL
LGG	chr9	2829886	Missense_Mutation	rs758633890	R247Q	0.32
LGG	chr9	2828698	Silent	novel	Q311Q	0.24
LGG	chr9	2831319	Missense_Mutation	NA	R181H	0.27
LGG	chr9	2829902	Missense_Mutation	rs558845198	V242M	0.23
LIHC	chr9	2812219	Splice_Site	novel	X471_splice	0.84
LIHC	chr9	2837227	Missense_Mutation	rs552128111	N86S	0.2
LUAD	chr9	2810388	Missense_Mutation	novel	W560L	0.26	CPL
LUAD	chr9	2804411	Frame_Shift_Ins	novel	*K623Hfs2**	0.26
LUAD	chr9	2804412	Frame_Shift_Ins	novel	*K623Efs22**	0.27
LUAD	chr9	2834129	Silent	NA	K114K	0.6
LUAD	chr9	2820023	Missense_Mutation	rs565664019	I422V	0.12
LUAD	chr9	2810374	Missense_Mutation	NA	D565N	0.15	CPL
LUAD	chr9	2811463	Silent	NA	V511V	0.16
LUAD	chr9	2812306	Silent	rs749127582	L442L	0.29
LUAD	chr9	2811432	Missense_Mutation	novel	V522F	0.19	CPL
LUSC	chr9	2834081	Frame_Shift_Ins	novel	*N131Pfs5**	0.09
LUSC	chr9	2811367	Silent	rs555132906	D543D	0.53
OV	chr9	2838437	Missense_Mutation	rs772434075	H24L	0.23
OV	chr9	2828779	Splice_Site	NA	X285_splice	0.2
OV	chr9	2831319	Missense_Mutation	NA	R181P	0.37
PAAD	chr9	2811514	Silent	novel	L494L	0.2
READ	chr9	2844133	5'UTR	novel		0.45
READ	chr9	2804310	3'UTR	novel		0.13
READ	chr9	2829945	Missense_Mutation	NA	S227R	0.35
READ	chr9	2837247	Missense_Mutation	NA	K79N	0.41
READ	chr9	2810367	Missense_Mutation	NA	K567T	0.3	CPL
SARC	chr9	2833369	Silent	novel	G168G	0.52
SKCM	chr9	2828681	Missense_Mutation	novel	A317G	0.69
SKCM	chr9	2837265	Silent	novel	Q73Q	0.79
SKCM	chr9	2804276	3'UTR	novel		0.23
SKCM	chr9	2831320	Missense_Mutation	rs758022107	R181C	0.73
SKCM	chr9	2812349	Missense_Mutation	novel	S428L	0.89
SKCM	chr9	2837348	Missense_Mutation	novel	P46S	0.73
STAD	chr9	2807900	Nonsense_Mutation	NA	C576*	0.29
STAD	chr9	2804407	Frame_Shift_Ins	novel	*S624Kfs21**	0.22
STAD	chr9	2829847	Missense_Mutation	NA	N260S	0.17
STAD	chr9	2838446	Frame_Shift_Del	novel	*N21Tfs45**	0.25
STAD	chr9	2811528	Silent	NA	L490L	0.16
STAD	chr9	2820070	Missense_Mutation	rs772602035	A406V	0.26
STAD	chr9	2831004	Missense_Mutation	NA	A212V	0.3
STAD	chr9	2831330	Silent	rs376066589	H177H	0.15
STAD	chr9	2838446	Frame_Shift_Del	novel	*N21Tfs45**	0.22
STAD	chr9	2811408	Missense_Mutation	rs767282708	A530T	0.25	CPL
STAD	chr9	2824797	Missense_Mutation	NA	R352C	0.3
STAD	chr9	2829854	Missense_Mutation	rs62534389	A258T	0.32
THCA	chr9	2838460	In_Frame_Ins	novel	T16_A17insILILIL	0.07
UCEC	chr9	2807836	Nonsense_Mutation	rs776719805	R598*	0.38
UCEC	chr9	2824758	Missense_Mutation	novel	A365T	0.44
UCEC	chr9	2829887	Missense_Mutation	NA	R247W	0.26
UCEC	chr9	2810431	Missense_Mutation	NA	L546F	0.36	CPL
UCEC	chr9	2829887	Missense_Mutation	NA	R247W	0.27
UCEC	chr9	2834154	Missense_Mutation	novel	K106R	0.36
UCEC	chr9	2844121	5'UTR	novel		0.42
UCEC	chr9	2829854	Missense_Mutation	rs62534389	A258T	0.39
UCEC	chr9	2810354	Silent	rs777592709	N571N	0.43
UCEC	chr9	2838453	Nonsense_Mutation	novel	E19*	0.03
UCEC	chr9	2844067	5'UTR	novel		0.29
UCEC	chr9	2830979	Missense_Mutation	novel	K220N	0.18
UCEC	chr9	2804188	3'UTR	novel		0.27
UCEC	chr9	2810395	Silent	novel	L558L	0.07
UCEC	chr9	2833374	Nonsense_Mutation	NA	Q167*	0.76
UCEC	chr9	2804291	3'UTR	novel		0.33
UCEC	chr9	2807836	Nonsense_Mutation	rs776719805	R598*	0.23
UCEC	chr9	2834062	Missense_Mutation	rs372409722	R137W	0.31
UCEC	chr9	2812220	Missense_Mutation	novel	S471I	0.16	CPL
UCEC	chr9	2824758	Missense_Mutation	novel	A365T	0.31
UCEC	chr9	2829903	Silent	rs573057088	H241H	0.3
UCEC	chr9	2811491	Missense_Mutation	novel	V502A	0.47	CPL
UCEC	chr9	2811576	Missense_Mutation	novel	D474Y	0.43	CPL
UCEC	chr9	2831260	Nonsense_Mutation	novel	E201*	0.15
UCEC	chr9	2811536	Missense_Mutation	novel	S487Y	0.27	CPL
UCEC	chr9	2834137	Missense_Mutation	novel	D112N	0.17
UCEC	chr9	2837234	Missense_Mutation	novel	P84S	0.41
UCEC	chr9	2820054	Missense_Mutation	novel	I411M	0.25
UCEC	chr9	2843974	Splice_Site	novel		0.07
UCEC	chr9	2838453	Nonsense_Mutation	novel	E19*	0.16
UCEC	chr9	2804294	3'UTR	rs558562059		0.46
UCEC	chr9	2804434	Missense_Mutation	novel	A615E	0.08
UCEC	chr9	2833419	Missense_Mutation	NA	K152Q	0.04
UCEC	chr9	2831275	Missense_Mutation	NA	K196Q	0.42
UCEC	chr9	2804212	3'UTR	novel		0.51
UCEC	chr9	2804235	3'UTR	novel		0.32
UCEC	chr9	2831329	Missense_Mutation	NA	D178N	0.3
UCEC	chr9	2810380	Missense_Mutation	novel	E563K	0.33	CPL
UCEC	chr9	2828674	Splice_Site	novel	X319_splice	0.24
UCS	chr9	2831329	Missense_Mutation	NA	D178N	0.28

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.152	0.073854
LAML	DEL	0.0052	0.24147
OV	DEL	0.4214	0.00059831
SARC	DEL	0.3268	5.1003e-05
TGCT	DEL	0.3867	7.3329e-05
THCA	DEL	0.0301	0.24038
THYM	DEL	0.0325	0.022012

Survival Analysis

Cancer	P-value	Q-value
SARC	0.017	Kaplan-Meier Survival Analysis
ACC	0.00011	Kaplan-Meier Survival Analysis
UCS	0.046	Kaplan-Meier Survival Analysis
PRAD	0.021	Kaplan-Meier Survival Analysis
KIRP	0.05	Kaplan-Meier Survival Analysis
PAAD	0.043	Kaplan-Meier Survival Analysis
PCPG	0.017	Kaplan-Meier Survival Analysis
READ	0.026	Kaplan-Meier Survival Analysis
LIHC	0.00068	Kaplan-Meier Survival Analysis
UVM	0.0044	Kaplan-Meier Survival Analysis
OV	0.03	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000080608 (Gene tree)
Gene ID: 9933
Gene Symbol: PUM3
Alias: XTP5|PEN|PUF6|hPUF-A|HA-8|KIAA0020
Full Name: pumilio RNA binding family member 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 123,773 bases
Position: chr9:2,720,469-2,844,241
Accession: 29676
RBP type: canonical RBP
Summary: (Pumilio RNA Binding Family Member 3) is a Protein Coding gene. Diseases associated with PUM3 include Teeth Hard Tissue Disease.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000380982	CPL	PF08144.11	2.6e-52	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
19319195	A novel puf-A gene predicted from evolutionary analysis is involved in the development of eyes and primordial germ-cells.	PLoS One	2009	Kuo MW	doi: 10.1371/journal.pone.0004980
19244342	Nuclear shuttling of She2p couples ASH1 mRNA localization to its translational repression by recruiting Loc1p and Puf6p.	Mol Biol Cell	2009 Apr	Shen Z	doi: 10.1091/mbc.E08-11-1151
18695046	Maternal mRNAs are regulated by diverse P body-related mRNP granules during early Caenorhabditis elegans development.	J Cell Biol	2008 Aug 11	Noble SL	doi: 10.1083/jcb.200802128.
17912365	An improved, bias-reduced probabilistic functional gene network of baker's yeast, Saccharomyces cerevisiae.	PLoS One	2007 Oct 3	Lee I	-
17234175	The RNA-binding proteins PUF-5, PUF-6, and PUF-7 reveal multiple systems for maternal mRNA regulation during C. elegans oogenesis.	Dev Biol	2007 Mar 15	Lublin AL	-
21266351	hPuf-A/KIAA0020 modulates PARP-1 cleavage upon genotoxic stress.	Cancer Res	2011 Feb 1	Chang HY	doi: 10.1158/0008-5472.CAN-10-1831
28450395	Binding of DEAD-box helicase Dhh1 to the 5'-untranslated region of ASH1 mRNA represses localized translation of ASH1 in yeast cells.	J Biol Chem	2017 Jun 9	Zhang Q	doi: 10.1074/jbc.M117.776492
29487181	Puf3 participates in ribosomal biogenesis in malaria parasites.	J Cell Sci	2018 Mar 26	Liang X	doi: 10.1242/jcs.212597.
22205700	Divergence of Pumilio/fem-3 mRNA binding factor (PUF) protein specificity through variations in an RNA-binding pocket.	J Biol Chem	2012 Feb 24	Qiu C	doi: 10.1074/jbc.M111.326264
18579869	A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity.	RNA	2008 Aug	Stumpf CR	doi: 10.1261/rna.1095908

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000490444	PUM3-204	340	-	ENSP00000474467	49 (aa)	-	S4R3K8
ENST00000397885	PUM3-202	2321	-	ENSP00000380982	648 (aa)	-	Q15397
ENST00000469168	PUM3-203	456	-	-	- (aa)	-	-
ENST00000382032	PUM3-201	458	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000080608's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000080608	Platelet Function Tests	1.0200000E-006	-
ENSG00000080608	Platelet Function Tests	7.1400000E-007	-
ENSG00000080608	Blood Pressure	9E-6	23251661

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000080608	rs2034764	9	2742771	?	Alzheimer's disease (age of onset)	22005931	unit increase	0.879	EFO_0000249\|EFO_0004847
ENSG00000080608	rs10812641	9	2777384	?	Blood trace element (Se levels)	23720494	[0.054-0.128] unit increase	0.091	EFO_0005266
ENSG00000080608	rs10968457	9	2838470	A	Obesity-related traits	23251661	[NR] mmHg increase	0.03	EFO_0006336
ENSG00000080608	rs117983281	9	2809077	?	Aspartate aminotransferase levels in low alcohol consumption	30589442	[0.091-0.199] unit increase	0.1449	EFO_0004736\|EFO_0007878

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000080608's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000080608	PUM3	98	54.167	ENSAPOG00000020252	pum3	81	61.101	Acanthochromis_polyacanthus
ENSG00000080608	PUM3	100	91.667	ENSAMEG00000012187	PUM3	100	91.667	Ailuropoda_melanoleuca
ENSG00000080608	PUM3	98	54.167	ENSACIG00000009786	pum3	88	57.656	Amphilophus_citrinellus
ENSG00000080608	PUM3	99	54.545	ENSAOCG00000004439	pum3	81	61.670	Amphiprion_ocellaris
ENSG00000080608	PUM3	99	54.545	ENSAPEG00000020523	pum3	81	61.670	Amphiprion_percula
ENSG00000080608	PUM3	98	58.333	ENSATEG00000005799	pum3	82	63.378	Anabas_testudineus
ENSG00000080608	PUM3	96	73.515	ENSAPLG00000002920	PUM3	100	73.515	Anas_platyrhynchos
ENSG00000080608	PUM3	93	67.987	ENSACAG00000003174	PUM3	99	70.199	Anolis_carolinensis
ENSG00000080608	PUM3	100	96.296	ENSANAG00000024520	PUM3	100	96.296	Aotus_nancymaae
ENSG00000080608	PUM3	99	55.251	ENSACLG00000001017	pum3	99	55.251	Astatotilapia_calliptera
ENSG00000080608	PUM3	91	65.821	ENSAMXG00000020911	pum3	92	65.821	Astyanax_mexicanus
ENSG00000080608	PUM3	100	91.358	ENSBTAG00000013357	PUM3	100	91.358	Bos_taurus
ENSG00000080608	PUM3	75	32.193	WBGene00014165	puf-12	64	32.193	Caenorhabditis_elegans
ENSG00000080608	PUM3	100	94.907	ENSCJAG00000010917	PUM3	100	94.907	Callithrix_jacchus
ENSG00000080608	PUM3	100	91.512	ENSCAFG00000002035	PUM3	99	91.512	Canis_familiaris
ENSG00000080608	PUM3	100	91.358	ENSCAFG00020026867	PUM3	99	91.358	Canis_lupus_dingo
ENSG00000080608	PUM3	100	91.049	ENSCHIG00000021559	PUM3	100	91.049	Capra_hircus
ENSG00000080608	PUM3	100	92.130	ENSTSYG00000007481	PUM3	100	92.130	Carlito_syrichta
ENSG00000080608	PUM3	100	86.287	ENSCAPG00000010592	-	99	86.420	Cavia_aperea
ENSG00000080608	PUM3	100	87.963	ENSCPOG00000008552	-	99	88.099	Cavia_porcellus
ENSG00000080608	PUM3	100	95.216	ENSCCAG00000032650	PUM3	100	95.216	Cebus_capucinus
ENSG00000080608	PUM3	100	97.377	ENSCATG00000024880	PUM3	100	97.377	Cercocebus_atys
ENSG00000080608	PUM3	100	90.741	ENSCLAG00000011892	PUM3	99	90.741	Chinchilla_lanigera
ENSG00000080608	PUM3	100	97.531	ENSCSAG00000008691	PUM3	100	97.531	Chlorocebus_sabaeus
ENSG00000080608	PUM3	98	85.417	ENSCHOG00000002535	PUM3	95	70.634	Choloepus_hoffmanni
ENSG00000080608	PUM3	100	72.994	ENSCPBG00000025470	PUM3	95	72.994	Chrysemys_picta_bellii
ENSG00000080608	PUM3	81	40.037	ENSCING00000024199	-	87	40.733	Ciona_intestinalis
ENSG00000080608	PUM3	91	39.409	ENSCSAVG00000006072	-	99	41.255	Ciona_savignyi
ENSG00000080608	PUM3	100	97.222	ENSCANG00000006142	PUM3	100	97.222	Colobus_angolensis_palliatus
ENSG00000080608	PUM3	100	91.204	ENSCGRG00001016402	Pum3	99	91.204	Cricetulus_griseus_chok1gshd
ENSG00000080608	PUM3	100	91.204	ENSCGRG00000010207	Pum3	99	91.204	Cricetulus_griseus_crigri
ENSG00000080608	PUM3	89	56.507	ENSCSEG00000001565	pum3	99	56.164	Cynoglossus_semilaevis
ENSG00000080608	PUM3	98	52.083	ENSCVAG00000006550	pum3	74	53.309	Cyprinodon_variegatus
ENSG00000080608	PUM3	95	66.132	ENSDARG00000087779	pum3	98	65.329	Danio_rerio
ENSG00000080608	PUM3	98	85.417	ENSDNOG00000008157	PUM3	70	79.167	Dasypus_novemcinctus
ENSG00000080608	PUM3	96	74.468	ENSETEG00000015331	PUM3	81	84.190	Echinops_telfairi
ENSG00000080608	PUM3	80	40.454	ENSEBUG00000011586	pum3	76	41.176	Eptatretus_burgeri
ENSG00000080608	PUM3	100	93.210	ENSEASG00005010350	PUM3	100	93.210	Equus_asinus_asinus
ENSG00000080608	PUM3	100	93.364	ENSECAG00000017193	PUM3	100	93.364	Equus_caballus
ENSG00000080608	PUM3	93	82.450	ENSEEUG00000010314	PUM3	100	82.450	Erinaceus_europaeus
ENSG00000080608	PUM3	98	60.526	ENSELUG00000002215	pum3	99	60.526	Esox_lucius
ENSG00000080608	PUM3	100	71.210	ENSFALG00000010509	PUM3	100	71.210	Ficedula_albicollis
ENSG00000080608	PUM3	99	91.036	ENSFDAG00000021027	PUM3	99	91.036	Fukomys_damarensis
ENSG00000080608	PUM3	89	60.471	ENSFHEG00000015576	pum3	99	60.471	Fundulus_heteroclitus
ENSG00000080608	PUM3	83	60.448	ENSGMOG00000014217	pum3	97	60.421	Gadus_morhua
ENSG00000080608	PUM3	99	69.432	ENSGALG00000010178	PUM3	100	70.245	Gallus_gallus
ENSG00000080608	PUM3	86	52.381	ENSGAFG00000001930	pum3	62	61.983	Gambusia_affinis
ENSG00000080608	PUM3	82	60.788	ENSGACG00000017878	pum3	96	60.911	Gasterosteus_aculeatus
ENSG00000080608	PUM3	100	72.840	ENSGAGG00000018983	PUM3	99	73.408	Gopherus_agassizii
ENSG00000080608	PUM3	100	100.000	ENSGGOG00000006143	PUM3	100	99.074	Gorilla_gorilla
ENSG00000080608	PUM3	98	54.167	ENSHBUG00000012903	pum3	80	57.455	Haplochromis_burtoni
ENSG00000080608	PUM3	100	90.432	ENSHGLG00000015868	-	99	90.432	Heterocephalus_glaber_female
ENSG00000080608	PUM3	100	90.432	ENSHGLG00100018825	PUM3	100	90.432	Heterocephalus_glaber_male
ENSG00000080608	PUM3	91	59.106	ENSHCOG00000010306	pum3	99	55.111	Hippocampus_comes
ENSG00000080608	PUM3	98	58.333	ENSIPUG00000024801	pum3	93	65.167	Ictalurus_punctatus
ENSG00000080608	PUM3	100	92.130	ENSSTOG00000009586	PUM3	99	92.130	Ictidomys_tridecemlineatus
ENSG00000080608	PUM3	99	89.181	ENSJJAG00000012563	Pum3	99	89.181	Jaculus_jaculus
ENSG00000080608	PUM3	86	60.000	ENSKMAG00000010277	pum3	99	55.346	Kryptolebias_marmoratus
ENSG00000080608	PUM3	99	54.111	ENSLBEG00000012213	pum3	99	54.179	Labrus_bergylta
ENSG00000080608	PUM3	99	65.491	ENSLACG00000008312	PUM3	99	66.104	Latimeria_chalumnae
ENSG00000080608	PUM3	99	65.278	ENSLOCG00000012529	pum3	99	65.278	Lepisosteus_oculatus
ENSG00000080608	PUM3	100	89.815	ENSLAFG00000017341	PUM3	99	89.815	Loxodonta_africana
ENSG00000080608	PUM3	100	97.531	ENSMFAG00000001430	PUM3	100	97.531	Macaca_fascicularis
ENSG00000080608	PUM3	100	97.531	ENSMMUG00000002362	PUM3	99	97.531	Macaca_mulatta
ENSG00000080608	PUM3	100	97.531	ENSMNEG00000035288	PUM3	100	97.531	Macaca_nemestrina
ENSG00000080608	PUM3	100	97.377	ENSMLEG00000034820	PUM3	100	97.377	Mandrillus_leucophaeus
ENSG00000080608	PUM3	96	57.447	ENSMAMG00000022861	pum3	81	62.548	Mastacembelus_armatus
ENSG00000080608	PUM3	99	55.030	ENSMZEG00005014205	pum3	97	55.030	Maylandia_zebra
ENSG00000080608	PUM3	99	64.122	ENSMGAG00000002255	PUM3	99	65.799	Meleagris_gallopavo
ENSG00000080608	PUM3	100	91.204	ENSMAUG00000009733	Pum3	99	91.204	Mesocricetus_auratus
ENSG00000080608	PUM3	100	93.673	ENSMICG00000045916	PUM3	87	93.673	Microcebus_murinus
ENSG00000080608	PUM3	100	90.895	ENSMOCG00000019519	-	99	90.895	Microtus_ochrogaster
ENSG00000080608	PUM3	100	86.574	ENSMOCG00000014830	-	100	86.111	Microtus_ochrogaster
ENSG00000080608	PUM3	98	52.083	ENSMMOG00000012184	pum3	83	58.065	Mola_mola
ENSG00000080608	PUM3	99	68.472	ENSMODG00000015417	PUM3	99	73.733	Monodelphis_domestica
ENSG00000080608	PUM3	98	52.083	ENSMALG00000022164	pum3	92	56.230	Monopterus_albus
ENSG00000080608	PUM3	100	89.352	MGP_CAROLIEiJ_G0022845	Pum3	99	89.352	Mus_caroli
ENSG00000080608	PUM3	100	89.506	ENSMUSG00000041360	Pum3	99	89.506	Mus_musculus
ENSG00000080608	PUM3	100	90.123	MGP_PahariEiJ_G0014338	Pum3	99	90.123	Mus_pahari
ENSG00000080608	PUM3	100	89.352	MGP_SPRETEiJ_G0023763	Pum3	99	89.352	Mus_spretus
ENSG00000080608	PUM3	100	87.963	ENSMPUG00000005125	PUM3	100	87.963	Mustela_putorius_furo
ENSG00000080608	PUM3	100	91.049	ENSMLUG00000002309	PUM3	100	91.049	Myotis_lucifugus
ENSG00000080608	PUM3	100	87.692	ENSNGAG00000019468	Pum3	100	87.692	Nannospalax_galili
ENSG00000080608	PUM3	98	52.083	ENSNBRG00000021370	pum3	79	61.034	Neolamprologus_brichardi
ENSG00000080608	PUM3	100	97.959	ENSNLEG00000008712	PUM3	100	97.685	Nomascus_leucogenys
ENSG00000080608	PUM3	75	59.959	ENSMEUG00000013606	-	96	58.471	Notamacropus_eugenii
ENSG00000080608	PUM3	79	78.511	ENSOPRG00000004225	-	79	78.511	Ochotona_princeps
ENSG00000080608	PUM3	99	90.108	ENSODEG00000003625	-	99	90.108	Octodon_degus
ENSG00000080608	PUM3	99	84.615	ENSODEG00000016477	-	99	84.615	Octodon_degus
ENSG00000080608	PUM3	99	54.299	ENSONIG00000012733	pum3	99	54.299	Oreochromis_niloticus
ENSG00000080608	PUM3	81	78.639	ENSOANG00000014995	PUM3	97	78.639	Ornithorhynchus_anatinus
ENSG00000080608	PUM3	100	90.741	ENSOCUG00000004189	-	100	90.741	Oryctolagus_cuniculus
ENSG00000080608	PUM3	99	90.078	ENSOCUG00000026104	-	100	90.078	Oryctolagus_cuniculus
ENSG00000080608	PUM3	91	55.952	ENSORLG00000014935	pum3	99	52.049	Oryzias_latipes
ENSG00000080608	PUM3	91	55.952	ENSORLG00020002841	pum3	99	52.049	Oryzias_latipes_hni
ENSG00000080608	PUM3	99	52.656	ENSORLG00015015906	pum3	99	52.200	Oryzias_latipes_hsok
ENSG00000080608	PUM3	98	52.083	ENSOMEG00000009427	pum3	99	52.207	Oryzias_melastigma
ENSG00000080608	PUM3	99	67.890	ENSOGAG00000033481	-	99	66.514	Otolemur_garnettii
ENSG00000080608	PUM3	100	91.834	ENSOGAG00000008125	-	99	91.975	Otolemur_garnettii
ENSG00000080608	PUM3	100	90.462	ENSOARG00000013337	PUM3	100	90.462	Ovis_aries
ENSG00000080608	PUM3	100	100.000	ENSPPAG00000041337	PUM3	100	99.228	Pan_paniscus
ENSG00000080608	PUM3	100	88.735	ENSPPRG00000000809	PUM3	100	88.735	Panthera_pardus
ENSG00000080608	PUM3	100	89.352	ENSPTIG00000021934	PUM3	100	89.352	Panthera_tigris_altaica
ENSG00000080608	PUM3	100	100.000	ENSPTRG00000020735	PUM3	100	99.383	Pan_troglodytes
ENSG00000080608	PUM3	100	97.531	ENSPANG00000025118	PUM3	100	97.531	Papio_anubis
ENSG00000080608	PUM3	99	64.715	ENSPKIG00000022249	pum3	98	65.584	Paramormyrops_kingsleyae
ENSG00000080608	PUM3	100	72.531	ENSPSIG00000016272	PUM3	100	72.531	Pelodiscus_sinensis
ENSG00000080608	PUM3	98	56.250	ENSPMGG00000021261	pum3	98	61.711	Periophthalmus_magnuspinnatus
ENSG00000080608	PUM3	98	85.417	ENSPEMG00000019340	-	99	89.524	Peromyscus_maniculatus_bairdii
ENSG00000080608	PUM3	90	78.246	ENSPCIG00000030598	PUM3	90	78.246	Phascolarctos_cinereus
ENSG00000080608	PUM3	98	52.083	ENSPFOG00000001719	pum3	95	56.784	Poecilia_formosa
ENSG00000080608	PUM3	98	52.083	ENSPLAG00000020010	pum3	82	61.260	Poecilia_latipinna
ENSG00000080608	PUM3	98	52.083	ENSPMEG00000017451	pum3	99	54.405	Poecilia_mexicana
ENSG00000080608	PUM3	100	97.994	ENSPPYG00000019255	PUM3	100	97.994	Pongo_abelii
ENSG00000080608	PUM3	100	76.698	ENSPCAG00000005797	PUM3	95	76.698	Procavia_capensis
ENSG00000080608	PUM3	100	92.901	ENSPCOG00000027325	PUM3	100	92.901	Propithecus_coquereli
ENSG00000080608	PUM3	100	89.815	ENSPVAG00000016135	PUM3	95	89.954	Pteropus_vampyrus
ENSG00000080608	PUM3	99	55.267	ENSPNYG00000016124	pum3	99	55.267	Pundamilia_nyererei
ENSG00000080608	PUM3	98	58.333	ENSPNAG00000026524	pum3	90	67.725	Pygocentrus_nattereri
ENSG00000080608	PUM3	100	88.580	ENSRNOG00000012574	Pum3	100	88.580	Rattus_norvegicus
ENSG00000080608	PUM3	100	88.272	ENSRNOG00000048356	RGD1308750	100	88.272	Rattus_norvegicus
ENSG00000080608	PUM3	100	96.914	ENSRBIG00000036924	PUM3	100	96.759	Rhinopithecus_bieti
ENSG00000080608	PUM3	100	97.068	ENSRROG00000041089	PUM3	100	97.068	Rhinopithecus_roxellana
ENSG00000080608	PUM3	100	96.451	ENSSBOG00000028066	PUM3	100	96.451	Saimiri_boliviensis_boliviensis
ENSG00000080608	PUM3	99	79.933	ENSSHAG00000003730	PUM3	99	78.241	Sarcophilus_harrisii
ENSG00000080608	PUM3	95	65.161	ENSSFOG00015018778	pum3	99	61.031	Scleropages_formosus
ENSG00000080608	PUM3	98	58.333	ENSSMAG00000013236	pum3	99	55.932	Scophthalmus_maximus
ENSG00000080608	PUM3	94	58.128	ENSSDUG00000001887	pum3	79	62.998	Seriola_dumerili
ENSG00000080608	PUM3	98	52.083	ENSSLDG00000015766	pum3	94	56.124	Seriola_lalandi_dorsalis
ENSG00000080608	PUM3	98	83.333	ENSSARG00000000579	PUM3	100	86.107	Sorex_araneus
ENSG00000080608	PUM3	97	70.175	ENSSPUG00000001707	PUM3	100	69.599	Sphenodon_punctatus
ENSG00000080608	PUM3	98	54.167	ENSSPAG00000003976	pum3	82	61.290	Stegastes_partitus
ENSG00000080608	PUM3	100	91.512	ENSSSCG00000005227	PUM3	99	91.575	Sus_scrofa
ENSG00000080608	PUM3	100	71.914	ENSTGUG00000005339	PUM3	100	71.914	Taeniopygia_guttata
ENSG00000080608	PUM3	96	55.673	ENSTRUG00000004074	pum3	79	62.786	Takifugu_rubripes
ENSG00000080608	PUM3	90	59.760	ENSTNIG00000010325	pum3	94	59.762	Tetraodon_nigroviridis
ENSG00000080608	PUM3	98	83.333	ENSTBEG00000013058	PUM3	86	70.916	Tupaia_belangeri
ENSG00000080608	PUM3	100	82.716	ENSTTRG00000001062	PUM3	96	82.716	Tursiops_truncatus
ENSG00000080608	PUM3	100	83.025	ENSUMAG00000018443	PUM3	99	85.958	Ursus_maritimus
ENSG00000080608	PUM3	100	91.371	ENSVPAG00000010766	PUM3	99	91.371	Vicugna_pacos
ENSG00000080608	PUM3	100	91.512	ENSVVUG00000006527	PUM3	99	91.512	Vulpes_vulpes
ENSG00000080608	PUM3	99	58.716	ENSXETG00000011707	pum3	99	58.725	Xenopus_tropicalis
ENSG00000080608	PUM3	98	54.167	ENSXCOG00000006725	pum3	87	58.779	Xiphophorus_couchianus
ENSG00000080608	PUM3	98	54.167	ENSXMAG00000002926	pum3	82	60.878	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	21266351.	IPI	Function
GO:0005654	nucleoplasm	21266351.	IDA	Component
GO:0005694	chromosome	20813266.	IDA	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	21266351.	IDA	Component
GO:0005783	endoplasmic reticulum	10942595.	IDA	Component
GO:0010835	regulation of protein ADP-ribosylation	21266351.	IMP	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.