Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
ACC | |||||||
ACC | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
DLBC | |||||||
ESCA | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
KICH | |||||||
KIRC | |||||||
KIRC | |||||||
KIRC | |||||||
KIRC | |||||||
LGG | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
OV | |||||||
OV | |||||||
OV | |||||||
PAAD | |||||||
PRAD | |||||||
PRAD | |||||||
READ | |||||||
READ | |||||||
READ | |||||||
READ | |||||||
SARC | |||||||
SARC | |||||||
SARC | |||||||
SARC | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
TGCT | |||||||
THCA | |||||||
THCA | |||||||
THYM | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
COAD | |||
READ |
Cancer | P-value | Q-value |
---|---|---|
KIRC | ||
SARC | ||
MESO | ||
ACC | ||
HNSC | ||
SKCM | ||
BRCA | ||
ESCA | ||
KIRP | ||
BLCA | ||
CESC | ||
READ | ||
UCEC | ||
LIHC | ||
LGG | ||
UVM | ||
OV |
PID | Title | Article | Time | Author | Doi |
---|---|---|---|---|---|
19940440 |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000371554 | HSP90AB1-202 | 2674 | XM_024446421 | ENSP00000360609 | 724 (aa) | XP_024302189 | P08238 |
ENST00000620073 | HSP90AB1-204 | 2644 | - | ENSP00000481908 | 724 (aa) | - | P08238 |
ENST00000371646 | HSP90AB1-203 | 2572 | - | ENSP00000360709 | 724 (aa) | - | P08238 |
ENST00000353801 | HSP90AB1-201 | 2582 | - | ENSP00000325875 | 724 (aa) | - | P08238 |
Pathway ID | Pathway Name | Source |
---|---|---|
hsa04141 | Protein processing in endoplasmic reticulum | KEGG |
hsa04151 | PI3K-Akt signaling pathway | KEGG |
hsa04217 | Necroptosis | KEGG |
hsa04612 | Antigen processing and presentation | KEGG |
hsa04621 | NOD-like receptor signaling pathway | KEGG |
hsa04657 | IL-17 signaling pathway | KEGG |
hsa04659 | Th17 cell differentiation | KEGG |
hsa04914 | Progesterone-mediated oocyte maturation | KEGG |
hsa04915 | Estrogen signaling pathway | KEGG |
hsa05200 | Pathways in cancer | KEGG |
hsa05215 | Prostate cancer | KEGG |
hsa05418 | Fluid shear stress and atherosclerosis | KEGG |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000096384 | HSP90AB1 | 99 | 75.522 | WBGene00000915 | daf-21 | 99 | 75.664 | Caenorhabditis_elegans |
ENSG00000096384 | HSP90AB1 | 99 | 78.462 | FBgn0001233 | Hsp83 | 99 | 78.481 | Drosophila_melanogaster |
ENSG00000096384 | HSP90AB1 | 83 | 45.540 | FBgn0026761 | Trap1 | 88 | 46.154 | Drosophila_melanogaster |
ENSG00000096384 | HSP90AB1 | 100 | 85.246 | ENSG00000080824 | HSP90AA1 | 98 | 86.134 | Homo_sapiens |
ENSG00000096384 | HSP90AB1 | 57 | 48.815 | ENSG00000166598 | HSP90B1 | 100 | 70.833 | Homo_sapiens |
ENSG00000096384 | HSP90AB1 | 85 | 46.411 | ENSG00000126602 | TRAP1 | 93 | 46.411 | Homo_sapiens |
ENSG00000096384 | HSP90AB1 | 100 | 99.586 | ENSMUSG00000023944 | Hsp90ab1 | 100 | 100.000 | Mus_musculus |
ENSG00000096384 | HSP90AB1 | 100 | 84.311 | ENSMUSG00000021270 | Hsp90aa1 | 91 | 93.443 | Mus_musculus |
ENSG00000096384 | HSP90AB1 | 95 | 47.286 | ENSMUSG00000020048 | Hsp90b1 | 89 | 49.699 | Mus_musculus |
ENSG00000096384 | HSP90AB1 | 84 | 46.411 | ENSMUSG00000005981 | Trap1 | 86 | 46.411 | Mus_musculus |
ENSG00000096384 | HSP90AB1 | 98 | 61.646 | YPL240C | HSP82 | 99 | 61.259 | Saccharomyces_cerevisiae |
ENSG00000096384 | HSP90AB1 | 61 | 60.762 | YMR186W | HSC82 | 99 | 61.150 | Saccharomyces_cerevisiae |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0001890 | placenta development | - | IEA | Process |
GO:0003723 | RNA binding | 22658674.22681889. | HDA | Function |
GO:0003725 | double-stranded RNA binding | 21266579. | IDA | Function |
GO:0005515 | protein binding | 21873635. | IBA | Function |
GO:0005515 | protein binding | 11036079.14743216.15358771.15581363.15657067.15870294.16293251.16314389.16330544.16531226.16580629.16698020.17932509.17979178.18239673.18320024.18818696.19375531.20029029.20374249.20618441.21170051.21183720.21360678.21730179.21988832.22022502.22843495.22939624.23349634.23414517.23428871.23431407.23455922.23585225.24189400.24581495.24613385.24618592.24658140.24880080.25036637.25241761.25416956.25486457.25609649.25910212.26496610.26517842.27339980.28330616.29127155.29568061. | IPI | Function |
GO:0005524 | ATP binding | 21873635. | IBA | Function |
GO:0005524 | ATP binding | 10811660. | IDA | Function |
GO:0005524 | ATP binding | 10543959. | IMP | Function |
GO:0005576 | extracellular region | 20599762. | IDA | Component |
GO:0005576 | extracellular region | - | TAS | Component |
GO:0005634 | nucleus | 18239673. | IDA | Component |
GO:0005654 | nucleoplasm | - | TAS | Component |
GO:0005737 | cytoplasm | 21873635. | IBA | Component |
GO:0005737 | cytoplasm | 10791971.11785981.16580629.18239673.24880080. | IDA | Component |
GO:0005739 | mitochondrion | 20833797. | HDA | Component |
GO:0005829 | cytosol | 21873635. | IBA | Component |
GO:0005829 | cytosol | - | IDA | Component |
GO:0005829 | cytosol | - | TAS | Component |
GO:0005886 | plasma membrane | - | IEA | Component |
GO:0006457 | protein folding | - | IEA | Process |
GO:0006805 | xenobiotic metabolic process | - | TAS | Process |
GO:0006986 | response to unfolded protein | 2768249. | NAS | Process |
GO:0007004 | telomere maintenance via telomerase | 10197982. | IDA | Process |
GO:0008180 | COP9 signalosome | 18850735. | IDA | Component |
GO:0016020 | membrane | 19946888. | HDA | Component |
GO:0019062 | virion attachment to host cell | 24098578. | IMP | Process |
GO:0019887 | protein kinase regulator activity | - | IEA | Function |
GO:0019900 | kinase binding | 20353823.21855797. | IPI | Function |
GO:0019901 | protein kinase binding | 21873635. | IBA | Function |
GO:0021955 | central nervous system neuron axonogenesis | - | ISS | Process |
GO:0023026 | MHC class II protein complex binding | 20458337. | HDA | Function |
GO:0030010 | establishment of cell polarity | - | ISS | Process |
GO:0030235 | nitric-oxide synthase regulator activity | - | ISS | Function |
GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway | 24613385. | IDA | Process |
GO:0030911 | TPR domain binding | - | ISS | Function |
GO:0031072 | heat shock protein binding | 20353823. | IPI | Function |
GO:0031396 | regulation of protein ubiquitination | 16809764. | IDA | Process |
GO:0031625 | ubiquitin protein ligase binding | 16207813. | IPI | Function |
GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | 24613385. | IDA | Process |
GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | 16280321. | IMP | Process |
GO:0032516 | positive regulation of phosphoprotein phosphatase activity | 26593036. | IDA | Process |
GO:0032991 | protein-containing complex | 10811660.23349634. | IDA | Component |
GO:0032991 | protein-containing complex | 10543959. | IMP | Component |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | - | ISS | Process |
GO:0034751 | aryl hydrocarbon receptor complex | 15581363. | IDA | Component |
GO:0034774 | secretory granule lumen | - | TAS | Component |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | - | TAS | Process |
GO:0042277 | peptide binding | 20599762. | IPI | Function |
GO:0042470 | melanosome | - | IEA | Component |
GO:0042623 | ATPase activity, coupled | - | TAS | Function |
GO:0042802 | identical protein binding | 21183720.22939624. | IPI | Function |
GO:0042803 | protein homodimerization activity | 10811660. | IDA | Function |
GO:0042826 | histone deacetylase binding | 16809764. | IPI | Function |
GO:0043008 | ATP-dependent protein binding | 10543959.10811660. | IPI | Function |
GO:0043025 | neuronal cell body | - | ISS | Component |
GO:0043066 | negative regulation of apoptotic process | - | IEA | Process |
GO:0043312 | neutrophil degranulation | - | TAS | Process |
GO:0044294 | dendritic growth cone | - | ISS | Component |
GO:0044295 | axonal growth cone | - | ISS | Component |
GO:0045296 | cadherin binding | 25468996. | HDA | Function |
GO:0045429 | positive regulation of nitric oxide biosynthetic process | - | ISS | Process |
GO:0045597 | positive regulation of cell differentiation | 18239673. | IMP | Process |
GO:0046983 | protein dimerization activity | 7588731. | IDA | Function |
GO:0048156 | tau protein binding | 28386764. | NAS | Function |
GO:0048471 | perinuclear region of cytoplasm | - | ISS | Component |
GO:0048675 | axon extension | - | ISS | Process |
GO:0050821 | protein stabilization | - | TAS | Process |
GO:0051082 | unfolded protein binding | - | IEA | Function |
GO:0051131 | chaperone-mediated protein complex assembly | 10811660. | IDA | Process |
GO:0051248 | negative regulation of protein metabolic process | 17517623. | ISS | Process |
GO:0051897 | positive regulation of protein kinase B signaling | - | ISS | Process |
GO:0051973 | positive regulation of telomerase activity | 10197982. | IDA | Process |
GO:0060334 | regulation of interferon-gamma-mediated signaling pathway | 16280321. | IMP | Process |
GO:0060338 | regulation of type I interferon-mediated signaling pathway | 16280321. | IMP | Process |
GO:0070062 | extracellular exosome | 20458337.23533145. | HDA | Component |
GO:0070182 | DNA polymerase binding | 10197982.19751963. | IPI | Function |
GO:0071157 | negative regulation of cell cycle arrest | 22843495. | IMP | Process |
GO:0071353 | cellular response to interleukin-4 | - | IEA | Process |
GO:0097435 | supramolecular fiber organization | 24466266. | IMP | Process |
GO:0097718 | disordered domain specific binding | 11785981.15713458. | IPI | Function |
GO:1900034 | regulation of cellular response to heat | - | TAS | Process |
GO:1901389 | negative regulation of transforming growth factor beta activation | 20599762. | IDA | Process |
GO:1901799 | negative regulation of proteasomal protein catabolic process | 21873635. | IBA | Process |
GO:1901799 | negative regulation of proteasomal protein catabolic process | 17517623. | ISS | Process |
GO:1902949 | positive regulation of tau-protein kinase activity | - | IC | Process |
GO:1903827 | regulation of cellular protein localization | 21873635. | IBA | Process |
GO:1903827 | regulation of cellular protein localization | - | ISS | Process |
GO:1904031 | positive regulation of cyclin-dependent protein kinase activity | 17517623. | ISS | Process |
GO:1904813 | ficolin-1-rich granule lumen | - | TAS | Component |
GO:1905323 | telomerase holoenzyme complex assembly | 10197982. | IDA | Process |
GO:1990226 | histone methyltransferase binding | 24880080. | IPI | Function |
GO:1990565 | HSP90-CDC37 chaperone complex | 21855797. | IDA | Component |
GO:2000010 | positive regulation of protein localization to cell surface | 23431407. | IDA | Process |