EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21075448	The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma.	Cell Calcium	2010 Dec	Shibao K	doi: 10.1016/j.ceca.2010.09.005
23992640	Molecular interaction and functional coupling between type 3 inositol 1,4,5-trisphosphate receptor and BKCa channel stimulate breast cancer cell proliferation.	Eur J Cancer	2013 Nov	Mound A	doi: 10.1016/j.ejca.2013.07.013
14666665	Possible involvement of inositol 1,4,5-trisphosphate receptor type 3 (IP3R3) in the peritoneal dissemination of gastric cancers.	Anticancer Res	2003 Sep-Oct	Sakakura C	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr6	33683339	Missense_Mutation	novel	P1577R	0.29
ACC	chr6	33689393	Missense_Mutation	novel	I2284F	0.43
ACC	chr6	33671198	Missense_Mutation	novel	G874S	0.24
ACC	chr6	33662569	Missense_Mutation	novel	F251L	0.47
ACC	chr6	33689239	Splice_Region	rs150616390	G2232G	0.25
BLCA	chr6	33669030	Missense_Mutation	novel	S688L	0.36
BLCA	chr6	33689298	Missense_Mutation	rs756560277	A2252V	0.06
BLCA	chr6	33670813	Missense_Mutation	novel	E862Q	0.21
BLCA	chr6	33689257	Silent	novel	L2238L	0.14
BLCA	chr6	33691699	Missense_Mutation	rs139781035	S2437L	0.59
BLCA	chr6	33692847	Silent	rs149058562	E2526E	0.39
BLCA	chr6	33693679	Missense_Mutation	NA	E2587Q	0.45
BLCA	chr6	33695641	Intron	novel		0.58
BLCA	chr6	33669052	Silent	NA	T695T	0.18
BLCA	chr6	33676789	Nonsense_Mutation	novel	Q1102*	0.08
BLCA	chr6	33669125	Frame_Shift_Del	novel	*A720Efs49**	0.06
BLCA	chr6	33680552	Splice_Region	NA		0.26
BLCA	chr6	33693702	Missense_Mutation	novel	I2594M	0.07
BLCA	chr6	33676815	Silent	novel	I1110I	0.14
BLCA	chr6	33686474	Silent	novel	I1978I	0.23
BLCA	chr6	33670776	Silent	rs776612517	V849V	0.2
BLCA	chr6	33685789	Silent	novel	L1877L	0.41
BLCA	chr6	33640517	Silent	rs777701344	A41A	0.2
BLCA	chr6	33665202	Missense_Mutation	NA	Q466H	0.21
BLCA	chr6	33680131	Missense_Mutation	novel	E1408K	0.25
BLCA	chr6	33671279	Missense_Mutation	NA	M901L	0.5
BLCA	chr6	33669016	Silent	novel	L683L	0.23
BLCA	chr6	33676765	Splice_Region	novel		0.27
BLCA	chr6	33655836	Silent	NA	T77T	0.43
BRCA	chr6	33688666	Silent	novel	L2193L	0.09
BRCA	chr6	33679931	Missense_Mutation	rs755528499	S1341L	0.21
BRCA	chr6	33686185	Missense_Mutation	rs778613128	V1934M	0.14
BRCA	chr6	33695095	Intron	novel		0.33
BRCA	chr6	33669111	Missense_Mutation	rs771869292	A715V	0.05
BRCA	chr6	33669145	Silent	novel	L726L	0.37
BRCA	chr6	33680368	Missense_Mutation	NA	V1422M	0.24
BRCA	chr6	33687276	Silent	rs778571725	S2042S	0.17
BRCA	chr6	33690104	Missense_Mutation	novel	A2313G	0.09
BRCA	chr6	33677090	Splice_Site	novel	X1174_splice	0.1
BRCA	chr6	33695721	Nonsense_Mutation	NA	Q2653*	0.71
BRCA	chr6	33690084	Silent	novel	T2306T	0.1
BRCA	chr6	33680054	Missense_Mutation	NA	Y1382F	0.2
BRCA	chr6	33663791	Missense_Mutation	NA	C353W	0.18
BRCA	chr6	33695174	Intron	novel		0.17
BRCA	chr6	33691910	Silent	novel	L2480L	0.07
BRCA	chr6	33621657	Missense_Mutation	NA	E19K	0.22
BRCA	chr6	33640540	Missense_Mutation	novel	P49L	0.08
BRCA	chr6	33688714	Silent	NA	F2209F	0.28
BRCA	chr6	33688404	Missense_Mutation	novel	E2181K	0.27
BRCA	chr6	33686119	Missense_Mutation	NA	D1912N	0.21
BRCA	chr6	33621657	Missense_Mutation	NA	E19Q	0.24
BRCA	chr6	33678725	Silent	rs144005144	F1286F	0.41
BRCA	chr6	33693605	Missense_Mutation	NA	E2562A	0.36
BRCA	chr6	33694999	Missense_Mutation	NA	E2621K	0.59
BRCA	chr6	33691715	Silent	novel	L2442L	0.09
BRCA	chr6	33672108	Missense_Mutation	NA	F936L	0.47
BRCA	chr6	33679986	Silent	NA	H1359H	0.9
BRCA	chr6	33672205	Missense_Mutation	rs373625572	L969M	0.38
CESC	chr6	33695600	Intron	rs547079667		0.31
CESC	chr6	33672100	Missense_Mutation	novel	S934T	0.36
CESC	chr6	33675769	Silent	novel	H1065H	0.31
CESC	chr6	33673637	Missense_Mutation	novel	S992F	0.16
CESC	chr6	33688380	Missense_Mutation	rs578183913	D2173N	0.28
CESC	chr6	33695740	Missense_Mutation	rs766896205	R2659H	0.36
CESC	chr6	33688268	Missense_Mutation	NA	Q2135H	0.13
CESC	chr6	33665097	Silent	rs373612197	I431I	0.19
CESC	chr6	33682574	Silent	novel	L1509L	0.23
CESC	chr6	33658699	Silent	novel	L133L	0.17
CESC	chr6	33680038	Missense_Mutation	NA	E1377K	0.39
CESC	chr6	33695857	3'UTR	rs565102433		0.45
CESC	chr6	33667186	Missense_Mutation	rs768879198	R537W	0.09
CESC	chr6	33663500	Missense_Mutation	novel	E319Q	0.06
CHOL	chr6	33663791	Missense_Mutation	NA	C353W	0.21
CHOL	chr6	33664890	Missense_Mutation	novel	R390Q	0.15
COAD	chr6	33677580	Missense_Mutation	novel	M1200T	0.14
COAD	chr6	33663822	Missense_Mutation	rs749099428	A364T	0.28
COAD	chr6	33695051	Missense_Mutation	NA	H2638R	0.2
COAD	chr6	33683305	Missense_Mutation	NA	A1566T	0.25
COAD	chr6	33665151	Missense_Mutation	novel	S449R	0.44
COAD	chr6	33688350	Missense_Mutation	novel	E2163K	0.08
COAD	chr6	33694811	Intron	novel		0.32
COAD	chr6	33676852	Nonsense_Mutation	novel	K1123*	0.29
COAD	chr6	33669073	Silent	novel	E702E	0.22
COAD	chr6	33664875	Missense_Mutation	rs753753894	S385L	0.25
COAD	chr6	33658813	Silent	NA	R171R	0.21
COAD	chr6	33692839	Missense_Mutation	NA	R2524C	0.35
COAD	chr6	33668567	Missense_Mutation	rs142075453	V647I	0.34
COAD	chr6	33662625	Missense_Mutation	rs777019225	R270H	0.39
COAD	chr6	33686435	Silent	novel	N1965N	0.31
COAD	chr6	33658725	Missense_Mutation	novel	L142S	0.38
COAD	chr6	33672183	Silent	NA	D961D	0.19
COAD	chr6	33680562	Missense_Mutation	NA	S1453N	0.35
COAD	chr6	33680028	Silent	rs758747831	A1373A	0.28
COAD	chr6	33663872	Silent	rs372786080	F380F	0.22
COAD	chr6	33667164	Frame_Shift_Del	NA	*G531Vfs50**	0.15
COAD	chr6	33686105	Missense_Mutation	NA	T1907M	0.25
COAD	chr6	33686185	Missense_Mutation	rs778613128	V1934M	0.28
COAD	chr6	33655794	Silent	NA	N63N	0.18
COAD	chr6	33683284	Missense_Mutation	NA	A1559T	0.28
COAD	chr6	33680636	Missense_Mutation	rs763726545	A1478T	0.39
COAD	chr6	33688323	Missense_Mutation	rs142820127	R2154W	0.37
COAD	chr6	33655769	Missense_Mutation	novel	C55F	0.14
COAD	chr6	33668555	Missense_Mutation	novel	I643F	0.18
COAD	chr6	33667898	Frame_Shift_Del	NA	*K608Sfs66**	0.34
COAD	chr6	33662612	Nonsense_Mutation	rs747619884	R266*	0.24
COAD	chr6	33670530	Missense_Mutation	rs767435428	F799L	0.21
COAD	chr6	33663804	Missense_Mutation	NA	P358S	0.3
COAD	chr6	33670404	Missense_Mutation	NA	V757M	0.13
COAD	chr6	33677053	Silent	novel	G1162G	0.16
COAD	chr6	33687231	Silent	rs766466833	D2027D	0.1
COAD	chr6	33694944	Frame_Shift_Del	NA	*R2604Gfs30**	0.27
COAD	chr6	33675732	Missense_Mutation	rs770956589	R1053H	0.53
COAD	chr6	33676915	Missense_Mutation	NA	A1144T	0.45
COAD	chr6	33682588	Missense_Mutation	NA	L1514P	0.49
COAD	chr6	33684872	Frame_Shift_Del	NA	*N1746Tfs30**	0.2
COAD	chr6	33665882	Missense_Mutation	NA	V486A	0.4
COAD	chr6	33680375	Missense_Mutation	novel	T1424M	0.1
COAD	chr6	33662932	Missense_Mutation	NA	R294C	0.47
COAD	chr6	33682610	Silent	rs571319160	S1521S	0.46
COAD	chr6	33677516	Silent	NA	L1179L	0.17
COAD	chr6	33684800	Missense_Mutation	rs756479384	A1722T	0.15
COAD	chr6	33692791	Missense_Mutation	NA	V2508M	0.3
COAD	chr6	33692830	Missense_Mutation	NA	A2521T	0.43
COAD	chr6	33686145	Silent	rs202114409	G1920G	0.18
COAD	chr6	33670522	Missense_Mutation	rs762693746	P796L	0.3
COAD	chr6	33662584	Silent	NA	E256E	0.28
COAD	chr6	33680038	Missense_Mutation	NA	E1377K	0.25
COAD	chr6	33680614	Silent	rs771140880	S1470S	0.31
COAD	chr6	33684634	Missense_Mutation	NA	L1695I	0.26
COAD	chr6	33694899	Intron	novel		0.19
COAD	chr6	33687527	Missense_Mutation	NA	R2076H	0.2
DLBC	chr6	33665210	Missense_Mutation	rs778958478	R469H	0.23
ESCA	chr6	33684143	Missense_Mutation	novel	C1638R	0.09
ESCA	chr6	33693672	Silent	rs183531106	T2584T	0.11
ESCA	chr6	33695998	3'UTR	novel		0.41
ESCA	chr6	33685804	Missense_Mutation	novel	E1882Q	0.31
ESCA	chr6	33678456	Silent	rs543118868	T1228T	0.36
ESCA	chr6	33685409	Silent	rs747022423	F1786F	0.11
GBM	chr6	33676818	Missense_Mutation	novel	K1111N	0.32
GBM	chr6	33694810	Intron	novel		0.27
GBM	chr6	33685705	Missense_Mutation	rs201614062	R1849C	0.29
GBM	chr6	33665858	Missense_Mutation	novel	D478A	0.05
GBM	chr6	33695153	Intron	novel		0.77
GBM	chr6	33659079	Missense_Mutation	novel	A196V	0.28
GBM	chr6	33667932	Silent	novel	F618F	0.29
GBM	chr6	33673711	Missense_Mutation	novel	D1017Y	0.32
GBM	chr6	33685503	Missense_Mutation	novel	D1818Y	0.52
GBM	chr6	33680645	Missense_Mutation	novel	S1481C	0.08
GBM	chr6	33695588	Intron	NA		0.49
GBM	chr6	33693587	Missense_Mutation	novel	E2556V	0.21
GBM	chr6	33665845	Nonsense_Mutation	NA	Q474*	0.23
GBM	chr6	33676838	Missense_Mutation	NA	R1118Q	0.1
GBM	chr6	33665878	Missense_Mutation	rs748147185	D485N	0.41
GBM	chr6	33672045	Silent	novel	R915R	0.18
GBM	chr6	33685705	Missense_Mutation	rs201614062	R1849C	0.49
GBM	chr6	33688161	Missense_Mutation	novel	Q2123H	0.3
GBM	chr6	33695147	Intron	novel		0.19
GBM	chr6	33680590	Silent	novel	P1462P	0.08
GBM	chr6	33686105	Missense_Mutation	NA	T1907M	0.32
GBM	chr6	33680591	Missense_Mutation	novel	T1463S	0.17
GBM	chr6	33695666	Intron	novel		0.05
GBM	chr6	33691008	Missense_Mutation	novel	L2375Q	0.08
HNSC	chr6	33678807	Missense_Mutation	novel	V1314L	0.37
HNSC	chr6	33688753	Missense_Mutation	novel	F2222L	0.2
HNSC	chr6	33689275	Missense_Mutation	novel	W2244C	0.2
HNSC	chr6	33695700	Intron	novel		0.26
HNSC	chr6	33684419	Missense_Mutation	novel	R1667P	0.28
HNSC	chr6	33692772	Silent	novel	F2501F	0.16
HNSC	chr6	33665874	Silent	novel	V483V	0.12
HNSC	chr6	33669133	Frame_Shift_Del	novel	*D722Efs12**	0.08
HNSC	chr6	33686189	Missense_Mutation	novel	G1935D	0.21
HNSC	chr6	33692778	Silent	rs767020507	I2503I	0.49
HNSC	chr6	33689235	Splice_Region	novel		0.41
HNSC	chr6	33669101	Missense_Mutation	novel	A712T	0.09
HNSC	chr6	33690992	Silent	novel	L2370L	0.06
HNSC	chr6	33692734	Missense_Mutation	novel	L2489V	0.16
HNSC	chr6	33670526	Silent	novel	V797V	0.12
HNSC	chr6	33675743	Missense_Mutation	rs556088693	R1057C	0.09
HNSC	chr6	33695076	Silent	novel	L2646L	0.37
HNSC	chr6	33691621	Missense_Mutation	rs752938750	P2411H	0.57
HNSC	chr6	33689397	Frame_Shift_Ins	novel	*A2287Cfs26**	0.44
HNSC	chr6	33692778	Silent	rs767020507	I2503I	0.33
HNSC	chr6	33691829	Silent	novel	R2453R	0.24
HNSC	chr6	33668581	Silent	NA	L651L	0.25
KIRC	chr6	33683215	Missense_Mutation	novel	R1536W	0.27
KIRC	chr6	33662618	Missense_Mutation	NA	T268A	0.13
KIRC	chr6	33694870	Intron	novel		0.35
KIRC	chr6	33672102	Silent	rs370555491	S934S	0.24
KIRC	chr6	33695653	Intron	novel		0.25
KIRP	chr6	33695679	Intron	novel		0.06
KIRP	chr6	33676822	Missense_Mutation	NA	E1113K	0.25
KIRP	chr6	33670404	Missense_Mutation	novel	V757L	0.88
KIRP	chr6	33665098	Missense_Mutation	NA	V432M	0.76
LAML	chr6	33689344	Silent	rs761992573	A2267A	0.47
LAML	chr6	33685708	Frame_Shift_Ins	novel	*H1852Afs11**	0.33
LAML	chr6	33670690	Missense_Mutation	rs747839088	A821T	0.38
LGG	chr6	33670689	Silent	rs778513669	N820N	0.1
LGG	chr6	33664902	Missense_Mutation	NA	T394N	0.07
LGG	chr6	33670491	Missense_Mutation	rs577602247	V786M	0.58
LGG	chr6	33675745	Silent	rs774110911	R1057R	0.25
LGG	chr6	33688324	Missense_Mutation	rs756358608	R2154Q	0.28
LGG	chr6	33682560	Missense_Mutation	rs757325241	T1505A	0.39
LGG	chr6	33665184	Silent	rs780808015	N460N	0.31
LGG	chr6	33665908	Missense_Mutation	novel	D495Y	0.12
LGG	chr6	33667240	Missense_Mutation	novel	L555M	0.39
LGG	chr6	33685426	Missense_Mutation	rs778950448	R1792H	0.3
LGG	chr6	33687305	Missense_Mutation	rs373691310	N2052S	0.36
LGG	chr6	33689355	Missense_Mutation	NA	R2271H	0.37
LGG	chr6	33695569	Intron	novel		0.43
LGG	chr6	33657995	Missense_Mutation	rs768293062	V116M	0.17
LGG	chr6	33659107	Silent	rs755640976	A205A	0.46
LGG	chr6	33664950	Missense_Mutation	rs765845561	E410G	0.33
LGG	chr6	33688370	Silent	novel	S2169S	0.09
LGG	chr6	33667238	Missense_Mutation	rs776134726	R554H	0.14
LIHC	chr6	33640504	Missense_Mutation	novel	V37A	0.31
LIHC	chr6	33663842	Missense_Mutation	novel	D370E	0.31
LIHC	chr6	33670458	Missense_Mutation	novel	A775S	0.36
LIHC	chr6	33689333	Missense_Mutation	NA	L2264I	0.42
LIHC	chr6	33683329	Missense_Mutation	rs531158838	R1574W	0.38
LIHC	chr6	33687099	Missense_Mutation	novel	E2024Q	0.1
LIHC	chr6	33687317	Missense_Mutation	NA	L2056Q	0.49
LIHC	chr6	33677081	Missense_Mutation	rs147513071	V1172I	0.16
LIHC	chr6	33675780	Missense_Mutation	NA	P1069L	0.28
LIHC	chr6	33684642	Missense_Mutation	NA	N1697K	0.31
LIHC	chr6	33672080	Missense_Mutation	NA	M927T	0.33
LIHC	chr6	33678461	Missense_Mutation	NA	Q1230R	0.3
LIHC	chr6	33689333	Missense_Mutation	NA	L2264I	0.07
LIHC	chr6	33684463	Missense_Mutation	rs748669362	R1682W	0.09
LUAD	chr6	33688342	Missense_Mutation	novel	E2160G	0.1
LUAD	chr6	33678756	Missense_Mutation	novel	V1297L	0.26
LUAD	chr6	33680615	Missense_Mutation	novel	V1471F	0.26
LUAD	chr6	33658828	Splice_Region	rs116499996	N176N	0.1
LUAD	chr6	33659530	Missense_Mutation	NA	L231Q	0.28
LUAD	chr6	33670340	Silent	rs757011659	L735L	0.34
LUAD	chr6	33680552	Splice_Region	NA		0.24
LUAD	chr6	33687275	Missense_Mutation	NA	S2042L	0.39
LUAD	chr6	33685676	Nonsense_Mutation	NA	S1839*	0.25
LUAD	chr6	33691054	Missense_Mutation	NA	F2390L	0.73
LUAD	chr6	33667921	Missense_Mutation	novel	V615L	0.15
LUAD	chr6	33667197	Missense_Mutation	NA	E540D	0.36
LUAD	chr6	33690184	Missense_Mutation	novel	F2340L	0.35
LUAD	chr6	33684664	Missense_Mutation	NA	D1705Y	0.22
LUAD	chr6	33670668	Splice_Region	novel		0.22
LUAD	chr6	33669022	Silent	rs561046732	I685I	0.1
LUAD	chr6	33672105	Silent	novel	V935V	0.09
LUAD	chr6	33690935	Missense_Mutation	NA	R2351C	0.19
LUAD	chr6	33687080	Silent	NA	L2017L	0.18
LUAD	chr6	33676913	Missense_Mutation	NA	A1143G	0.23
LUAD	chr6	33691638	Nonsense_Mutation	novel	G2417*	0.54
LUAD	chr6	33658801	Silent	rs370534623	F167F	0.29
LUAD	chr6	33684659	Frame_Shift_Del	rs753781307	*D1705Tfs6**	0.16
LUAD	chr6	33664902	Missense_Mutation	NA	T394N	0.31
LUAD	chr6	33664962	Missense_Mutation	NA	R414L	0.27
LUAD	chr6	33684828	Missense_Mutation	novel	E1731A	0.35
LUAD	chr6	33682583	Silent	rs773138921	P1512P	0.18
LUAD	chr6	33670454	Silent	novel	L773L	0.29
LUAD	chr6	33670455	Missense_Mutation	rs200526442	R774C	0.29
LUAD	chr6	33689235	Splice_Region	novel		0.1
LUAD	chr6	33640539	Missense_Mutation	NA	P49S	0.3
LUSC	chr6	33671245	Silent	novel	L889L	0.1
LUSC	chr6	33688289	Silent	rs752663456	G2142G	0.28
LUSC	chr6	33663872	Silent	rs372786080	F380F	0.14
LUSC	chr6	33684364	Missense_Mutation	novel	Q1649K	0.23
LUSC	chr6	33659062	Silent	NA	A190A	0.12
LUSC	chr6	33659063	Missense_Mutation	NA	G191W	0.11
LUSC	chr6	33684453	Silent	rs755082712	K1678K	0.16
LUSC	chr6	33664897	Silent	novel	L392L	0.48
LUSC	chr6	33680555	Missense_Mutation	novel	V1451L	0.26
LUSC	chr6	33673641	Silent	NA	V993V	0.54
LUSC	chr6	33689255	Missense_Mutation	novel	L2238V	0.26
LUSC	chr6	33685804	Missense_Mutation	novel	E1882Q	0.66
LUSC	chr6	33664952	Missense_Mutation	novel	R411W	0.25
LUSC	chr6	33665213	Missense_Mutation	novel	R470M	0.12
LUSC	chr6	33672127	Missense_Mutation	novel	A943S	0.09
LUSC	chr6	33667211	Missense_Mutation	NA	K545R	0.27
LUSC	chr6	33685471	Missense_Mutation	novel	N1807S	0.13
LUSC	chr6	33694784	Intron	novel		0.5
LUSC	chr6	33670692	Silent	NA	A821A	0.2
LUSC	chr6	33684603	Silent	novel	N1684N	0.13
LUSC	chr6	33692784	In_Frame_Ins	novel	I2506_I2507dup	0.3
LUSC	chr6	33658748	Missense_Mutation	novel	V150M	0.56
LUSC	chr6	33670776	Silent	novel	V849V	0.51
LUSC	chr6	33695715	Missense_Mutation	novel	T2651S	0.16
LUSC	chr6	33664880	Missense_Mutation	NA	V387F	0.57
LUSC	chr6	33684803	Missense_Mutation	novel	A1723T	0.31
LUSC	chr6	33680067	Missense_Mutation	novel	K1386N	0.58
LUSC	chr6	33687560	Missense_Mutation	novel	S2087C	0.13
LUSC	chr6	33659029	Frame_Shift_Del	novel	*D181Tfs3**	0.79
LUSC	chr6	33670748	Missense_Mutation	novel	Y840C	0.39
OV	chr6	33695106	Intron	novel		0.04
OV	chr6	33658705	Silent	novel	V135V	0.04
OV	chr6	33680085	Silent	novel	P1392P	0.04
OV	chr6	33695576	Intron	novel		0.28
OV	chr6	33679929	Frame_Shift_Ins	novel	*S1341Vfs44**	0.09
OV	chr6	33674258	Missense_Mutation	novel	G1037R	0.08
OV	chr6	33684818	Silent	novel	L1728L	0.1
OV	chr6	33690987	In_Frame_Del	novel	S2368_I2369delinsF	0.17
OV	chr6	33690062	Missense_Mutation	novel	S2299I	0.08
OV	chr6	33694969	Frame_Shift_Ins	novel	*V2611Afs24**	0.09
OV	chr6	33673627	Missense_Mutation	novel	Y989D	0.06
OV	chr6	33680664	Missense_Mutation	NA	N1487S	0.2
OV	chr6	33688390	Missense_Mutation	novel	S2176F	0.18
OV	chr6	33695000	Missense_Mutation	novel	E2621V	0.2
OV	chr6	33680389	Nonsense_Mutation	novel	K1429*	0.08
OV	chr6	33695008	Missense_Mutation	novel	I2624L	0.64
OV	chr6	33664949	Missense_Mutation	NA	E410K	0.47
OV	chr6	33690034	Missense_Mutation	novel	L2290M	0.06
OV	chr6	33667233	Missense_Mutation	novel	M552I	0.25
OV	chr6	33659119	Frame_Shift_Ins	novel	*V210Cfs46**	0.14
OV	chr6	33691847	Missense_Mutation	novel	L2459F	0.05
OV	chr6	33672027	Splice_Site	NA	X910_splice	0.31
OV	chr6	33668581	Silent	NA	L651L	0.18
OV	chr6	33671226	Missense_Mutation	novel	R883P	0.08
PAAD	chr6	33672049	Missense_Mutation	rs754127262	I917V	0.12
PAAD	chr6	33659117	Nonsense_Mutation	novel	E209*	0.04
PAAD	chr6	33662641	Silent	rs569007497	S275S	0.15
PAAD	chr6	33665917	Missense_Mutation	novel	V498F	0.18
PAAD	chr6	33667186	Missense_Mutation	rs768879198	R537W	0.16
PAAD	chr6	33684389	Missense_Mutation	rs766016611	S1657L	0.18
PAAD	chr6	33688255	Missense_Mutation	rs766040259	R2131H	0.16
PAAD	chr6	33695739	Missense_Mutation	rs138851075	R2659C	0.18
PAAD	chr6	33695830	3'UTR	rs777189592		0.17
PCPG	chr6	33684827	Missense_Mutation	novel	E1731K	0.08
PRAD	chr6	33684851	Missense_Mutation	novel	D1739H	0.2
PRAD	chr6	33691085	Silent	novel	R2401R	0.05
PRAD	chr6	33677073	Frame_Shift_Del	novel	*Y1169Sfs11**	0.03
PRAD	chr6	33672040	Missense_Mutation	rs566710188	R914W	0.27
PRAD	chr6	33686184	Silent	rs149221361	N1933N	0.25
PRAD	chr6	33688258	Missense_Mutation	novel	S2132I	0.42
PRAD	chr6	33695695	Intron	novel		0.31
PRAD	chr6	33688420	Missense_Mutation	rs763958223	R2186H	0.09
READ	chr6	33691075	Silent	NA	L2397L	0.27
READ	chr6	33691090	Silent	rs751450550	L2402L	0.34
READ	chr6	33676912	Missense_Mutation	rs373241450	A1143T	0.3
SARC	chr6	33662931	Silent	novel	C293C	0.47
SARC	chr6	33662932	Missense_Mutation	NA	R294C	0.47
SARC	chr6	33687319	Missense_Mutation	novel	A2057S	0.13
SARC	chr6	33678473	Missense_Mutation	novel	K1234R	0.42
SKCM	chr6	33663851	Silent	NA	T373T	0.15
SKCM	chr6	33658737	Missense_Mutation	novel	N146S	0.19
SKCM	chr6	33658738	Silent	rs2296344	N146N	0.2
SKCM	chr6	33667962	Splice_Region	novel	P628P	0.35
SKCM	chr6	33680009	Missense_Mutation	NA	S1367F	0.14
SKCM	chr6	33678773	Silent	novel	F1302F	0.3
SKCM	chr6	33688301	Silent	NA	F2146F	0.27
SKCM	chr6	33665089	Missense_Mutation	novel	F429V	0.15
SKCM	chr6	33673593	Splice_Region	NA	F977F	0.15
SKCM	chr6	33676842	Silent	novel	T1119T	0.21
SKCM	chr6	33695849	3'UTR	novel		0.31
SKCM	chr6	33655794	Silent	NA	N63N	0.09
SKCM	chr6	33665109	Silent	NA	P435P	0.17
SKCM	chr6	33680352	Silent	rs201389648	F1416F	0.27
SKCM	chr6	33672047	Missense_Mutation	NA	S916F	0.35
SKCM	chr6	33672153	Silent	NA	L951L	0.3
SKCM	chr6	33640508	Silent	NA	V38V	0.12
SKCM	chr6	33675784	Silent	NA	L1070L	0.09
SKCM	chr6	33682582	Missense_Mutation	rs771517190	P1512L	0.26
SKCM	chr6	33686115	Silent	NA	F1910F	0.18
SKCM	chr6	33680438	Missense_Mutation	NA	T1445I	0.15
SKCM	chr6	33667216	Missense_Mutation	rs752466498	A547T	0.21
SKCM	chr6	33690066	Silent	rs749018804	F2300F	0.35
SKCM	chr6	33679931	Missense_Mutation	rs755528499	S1341L	0.25
SKCM	chr6	33688710	Missense_Mutation	NA	S2208F	0.52
SKCM	chr6	33684785	Missense_Mutation	NA	D1717N	0.27
SKCM	chr6	33684914	Silent	NA	L1760L	0.49
SKCM	chr6	33685780	Silent	novel	L1874L	0.38
SKCM	chr6	33691893	Missense_Mutation	novel	G2475S	0.22
SKCM	chr6	33692764	Silent	rs772189956	L2499L	0.26
SKCM	chr6	33662570	Silent	NA	L252L	0.35
SKCM	chr6	33688750	Silent	NA	F2221F	0.24
SKCM	chr6	33672181	Missense_Mutation	NA	D961Y	0.16
SKCM	chr6	33688394	Silent	NA	F2177F	0.84
SKCM	chr6	33685757	Missense_Mutation	NA	S1866F	0.23
SKCM	chr6	33662602	Silent	novel	Q262Q	0.96
SKCM	chr6	33669054	Nonsense_Mutation	novel	W696*	0.17
SKCM	chr6	33669055	Missense_Mutation	novel	W696C	0.17
SKCM	chr6	33640539	Missense_Mutation	NA	P49S	0.19
SKCM	chr6	33640540	Missense_Mutation	novel	P49L	0.19
SKCM	chr6	33692882	Missense_Mutation	NA	C2538Y	0.32
SKCM	chr6	33673593	Splice_Region	NA	F977F	0.15
SKCM	chr6	33684889	Silent	novel	Q1751Q	0.29
SKCM	chr6	33684890	Missense_Mutation	novel	E1752K	0.29
SKCM	chr6	33664936	Silent	novel	I405I	0.26
SKCM	chr6	33665065	Missense_Mutation	novel	P421S	0.36
SKCM	chr6	33686502	Silent	novel	L1988L	0.54
SKCM	chr6	33640539	Missense_Mutation	NA	P49S	0.24
STAD	chr6	33640497	Missense_Mutation	NA	R35C	0.36
STAD	chr6	33640534	Frame_Shift_Ins	novel	K50*	0.16
STAD	chr6	33670458	Missense_Mutation	NA	A775T	0.19
STAD	chr6	33691619	Frame_Shift_Del	NA	*L2412Wfs48**	0.46
STAD	chr6	33670774	Missense_Mutation	rs200072171	V849M	0.07
STAD	chr6	33667156	Missense_Mutation	rs139434169	R527C	0.28
STAD	chr6	33685726	Missense_Mutation	NA	E1856K	0.31
STAD	chr6	33691700	Silent	rs113565114	S2437S	0.68
STAD	chr6	33680364	Silent	NA	C1420C	0.12
STAD	chr6	33682566	Missense_Mutation	rs746407544	R1507C	0.26
STAD	chr6	33675727	Silent	novel	G1051G	0.17
STAD	chr6	33686106	Silent	rs189648121	T1907T	0.23
STAD	chr6	33669046	Missense_Mutation	NA	W693C	0.32
STAD	chr6	33691086	Missense_Mutation	NA	R2401L	0.42
STAD	chr6	33664927	Silent	NA	N402N	0.37
STAD	chr6	33684659	Frame_Shift_Del	rs753781307	*D1705Tfs6**	0.26
STAD	chr6	33691109	Missense_Mutation	NA	A2409S	0.23
STAD	chr6	33667164	Frame_Shift_Del	NA	*G531Vfs50**	0.28
STAD	chr6	33679963	Missense_Mutation	rs368822884	A1352T	0.5
STAD	chr6	33683299	Missense_Mutation	novel	R1564W	1
STAD	chr6	33685652	Missense_Mutation	rs776342387	A1831V	0.36
STAD	chr6	33658740	Missense_Mutation	NA	A147V	0.67
STAD	chr6	33668541	Missense_Mutation	rs770317269	C638Y	0.54
STAD	chr6	33670692	Silent	rs202110116	A821A	0.26
STAD	chr6	33684852	Missense_Mutation	NA	D1739G	0.08
STAD	chr6	33684924	Missense_Mutation	NA	G1763A	0.14
STAD	chr6	33677070	Missense_Mutation	novel	N1168T	0.44
STAD	chr6	33684077	Missense_Mutation	rs753819461	V1616M	0.4
STAD	chr6	33688726	Silent	rs750196911	V2213V	0.24
STAD	chr6	33680398	Missense_Mutation	NA	Y1432H	0.16
STAD	chr6	33694983	Silent	rs141751520	G2615G	0.47
STAD	chr6	33678724	Missense_Mutation	novel	F1286C	0.44
STAD	chr6	33663872	Silent	rs372786080	F380F	0.32
STAD	chr6	33670455	Missense_Mutation	rs200526442	R774C	0.34
STAD	chr6	33673710	Silent	rs146528103	F1016F	0.32
STAD	chr6	33690939	Missense_Mutation	NA	E2352G	0.2
STAD	chr6	33670386	Missense_Mutation	NA	I751L	0.21
STAD	chr6	33670347	Missense_Mutation	rs780991974	R738C	0.12
STAD	chr6	33688780	Splice_Region	novel	T2231T	0.08
STAD	chr6	33695072	Missense_Mutation	NA	E2645G	0.19
STAD	chr6	33686426	Silent	rs145776727	H1962H	0.19
STAD	chr6	33665103	Silent	rs753117025	S433S	0.17
STAD	chr6	33693698	Missense_Mutation	novel	M2593T	0.11
STAD	chr6	33663759	Missense_Mutation	rs369824854	R343C	0.11
STAD	chr6	33689297	Missense_Mutation	NA	A2252S	0.07
STAD	chr6	33695629	Intron	rs61051880		0.12
STAD	chr6	33687289	Missense_Mutation	rs760282940	R2047C	0.2
STAD	chr6	33675729	Missense_Mutation	NA	G1052D	0.27
STAD	chr6	33695731	Missense_Mutation	NA	R2656H	0.2
STAD	chr6	33640491	Missense_Mutation	novel	D33H	0.14
STAD	chr6	33684875	Missense_Mutation	NA	E1747K	0.29
STAD	chr6	33685689	Silent	rs772326452	S1843S	0.29
STAD	chr6	33680651	Missense_Mutation	novel	P1483T	0.08
STAD	chr6	33674229	Missense_Mutation	NA	R1027H	0.3
STAD	chr6	33689328	Missense_Mutation	rs776633313	R2262H	0.23
STAD	chr6	33640520	Silent	rs141205726	A42A	0.38
STAD	chr6	33695683	Intron	novel		0.19
STAD	chr6	33655830	Silent	NA	K75K	0.22
STAD	chr6	33670692	Silent	rs202110116	A821A	0.24
STAD	chr6	33689382	Missense_Mutation	NA	P2280H	0.27
STAD	chr6	33694894	Intron	novel		0.26
STAD	chr6	33684800	Missense_Mutation	rs756479384	A1722T	0.19
STAD	chr6	33688663	Silent	rs762470840	P2192P	0.34
STAD	chr6	33692839	Missense_Mutation	NA	R2524C	0.1
STAD	chr6	33671178	Missense_Mutation	NA	A867V	0.21
STAD	chr6	33693557	Missense_Mutation	NA	D2546G	0.18
STAD	chr6	33640515	Missense_Mutation	rs149697160	A41T	0.91
TGCT	chr6	33684643	Missense_Mutation	novel	R1698G	0.22
THCA	chr6	33695534	Intron	novel		0.14
UCEC	chr6	33657936	Missense_Mutation	rs376628421	A96V	0.43
UCEC	chr6	33677537	Frame_Shift_Del	novel	*E1187Sfs3**	0.38
UCEC	chr6	33663751	Missense_Mutation	rs773223069	R340H	0.46
UCEC	chr6	33655796	Missense_Mutation	rs747527908	R64H	0.44
UCEC	chr6	33657938	Missense_Mutation	novel	A97T	0.17
UCEC	chr6	33672056	Missense_Mutation	novel	G919D	0.47
UCEC	chr6	33680636	Missense_Mutation	rs763726545	A1478T	0.15
UCEC	chr6	33691912	Missense_Mutation	rs747686553	R2481H	0.44
UCEC	chr6	33696007	3'UTR	novel		0.49
UCEC	chr6	33665076	Silent	NA	E424E	0.33
UCEC	chr6	33688349	Silent	rs772497157	D2162D	0.4
UCEC	chr6	33684871	Missense_Mutation	novel	K1745N	0.29
UCEC	chr6	33695005	Missense_Mutation	rs778145976	R2623W	0.09
UCEC	chr6	33669157	Splice_Site	NA	X730_splice	0.54
UCEC	chr6	33678456	Silent	rs543118868	T1228T	0.49
UCEC	chr6	33680004	Silent	novel	H1365H	0.4
UCEC	chr6	33690049	Missense_Mutation	rs59525809	V2295M	0.38
UCEC	chr6	33621682	Missense_Mutation	novel	S27I	0.22
UCEC	chr6	33658720	Silent	rs149436819	P140P	0.48
UCEC	chr6	33662625	Missense_Mutation	rs777019225	R270H	0.36
UCEC	chr6	33664909	Silent	rs548084731	T396T	0.45
UCEC	chr6	33669131	Missense_Mutation	rs753604364	D722N	0.41
UCEC	chr6	33670756	Missense_Mutation	novel	N843D	0.31
UCEC	chr6	33676795	Missense_Mutation	novel	V1104M	0.45
UCEC	chr6	33680105	Missense_Mutation	novel	V1399A	0.41
UCEC	chr6	33682535	Silent	rs372206046	T1496T	0.31
UCEC	chr6	33692821	Missense_Mutation	novel	D2518N	0.3
UCEC	chr6	33662938	Nonsense_Mutation	NA	G296*	0.24
UCEC	chr6	33668996	Missense_Mutation	novel	A677T	0.08
UCEC	chr6	33669147	Missense_Mutation	novel	S727I	0.21
UCEC	chr6	33670332	Silent	novel	L733L	0.08
UCEC	chr6	33692843	Missense_Mutation	novel	S2525I	0.04
UCEC	chr6	33695173	Intron	novel		0.22
UCEC	chr6	33663822	Missense_Mutation	rs749099428	A364T	0.43
UCEC	chr6	33667216	Missense_Mutation	rs752466498	A547T	0.17
UCEC	chr6	33688247	Silent	novel	R2128R	0.44
UCEC	chr6	33675828	Missense_Mutation	novel	R1085H	0.13
UCEC	chr6	33693654	Silent	rs769686159	K2578K	0.12
UCEC	chr6	33658000	Missense_Mutation	novel	K117N	0.29
UCEC	chr6	33692840	Missense_Mutation	NA	R2524H	0.23
UCEC	chr6	33667157	Missense_Mutation	rs377347193	R527H	0.18
UCEC	chr6	33667937	Missense_Mutation	novel	S620N	0.13
UCEC	chr6	33668559	Missense_Mutation	novel	A644V	0.32
UCEC	chr6	33674207	Splice_Site	NA	X1020_splice	0.12
UCEC	chr6	33667152	Silent	NA	P525P	0.43
UCEC	chr6	33675729	Missense_Mutation	NA	G1052D	0.33
UCEC	chr6	33669023	Missense_Mutation	novel	E686K	0.21
UCEC	chr6	33686442	Missense_Mutation	novel	D1968Y	0.07
UCEC	chr6	33665061	Silent	novel	T419T	0.38
UCEC	chr6	33668604	Missense_Mutation	novel	P659H	0.37
UCEC	chr6	33680567	Missense_Mutation	rs760310772	R1455C	0.36
UCEC	chr6	33676794	Silent	rs371286972	D1103D	0.42
UCEC	chr6	33673683	Frame_Shift_Ins	novel	*A1009Gfs2**	0.33
UCEC	chr6	33669125	Missense_Mutation	rs750764933	A720T	0.31
UCEC	chr6	33692853	Silent	NA	Q2528Q	0.21
UCEC	chr6	33670690	Missense_Mutation	rs747839088	A821T	0.27
UCEC	chr6	33672113	Frame_Shift_Del	novel	*S940Afs25**	0.33
UCEC	chr6	33662665	Missense_Mutation	novel	W283C	0.11
UCEC	chr6	33678471	Silent	novel	Q1233Q	0.47
UCEC	chr6	33695791	3'UTR	rs781032975		0.31
UCEC	chr6	33640514	Silent	rs764696860	P40P	0.6
UCEC	chr6	33658721	Missense_Mutation	novel	A141T	0.38
UCEC	chr6	33665187	Silent	novel	E461E	0.46
UCEC	chr6	33691044	Missense_Mutation	novel	G2387D	0.44
UCEC	chr6	33667152	Silent	NA	P525P	0.38
UCEC	chr6	33692840	Missense_Mutation	NA	R2524H	0.22
UCEC	chr6	33677080	Silent	rs375729259	I1171I	0.49
UCEC	chr6	33682635	Missense_Mutation	novel	A1530T	0.3
UCEC	chr6	33689296	Silent	rs750556387	I2251I	0.42
UCEC	chr6	33696061	3'UTR	novel		0.1
UCEC	chr6	33664968	Missense_Mutation	NA	M416T	0.3
UCEC	chr6	33662559	Missense_Mutation	novel	Q248R	0.37
UCEC	chr6	33662641	Silent	rs569007497	S275S	0.35
UCEC	chr6	33687320	Missense_Mutation	rs756219025	A2057V	0.38
UCEC	chr6	33694980	Missense_Mutation	NA	E2614D	0.29
UCEC	chr6	33655765	Splice_Site	novel	X54_splice	0.21
UCEC	chr6	33684883	Silent	novel	I1749I	0.29
UCEC	chr6	33674229	Missense_Mutation	NA	R1027H	0.53
UCEC	chr6	33694696	Intron	novel		0.21
UCEC	chr6	33683328	Silent	rs746631398	T1573T	0.32
UCEC	chr6	33662625	Missense_Mutation	rs777019225	R270H	0.42
UCEC	chr6	33663872	Silent	rs372786080	F380F	0.22
UCEC	chr6	33696520	3'UTR	rs572500593		0.19
UCEC	chr6	33670472	Silent	novel	H779H	0.52
UCEC	chr6	33662576	Missense_Mutation	novel	C254R	0.61
UCEC	chr6	33663760	Missense_Mutation	rs150170523	R343H	0.1
UCEC	chr6	33684146	Missense_Mutation	rs369673229	E1639K	0.32
UCEC	chr6	33686189	Missense_Mutation	novel	G1935D	0.38
UCEC	chr6	33696162	3'UTR	rs535570371		0.3
UCEC	chr6	33669073	Silent	novel	E702E	0.29
UCEC	chr6	33690066	Silent	rs749018804	F2300F	0.3
UCEC	chr6	33675744	Missense_Mutation	rs763191989	R1057H	0.4
UCEC	chr6	33680074	Missense_Mutation	novel	S1389P	0.46
UCEC	chr6	33670348	Missense_Mutation	rs749462828	R738H	0.4
UCEC	chr6	33679963	Missense_Mutation	rs368822884	A1352T	0.33
UCEC	chr6	33690048	Silent	rs146604048	I2294I	0.34
UCEC	chr6	33693606	Missense_Mutation	novel	E2562D	0.4
UCEC	chr6	33695142	Intron	novel		0.28
UCEC	chr6	33621558	5'UTR	novel		0.33
UCEC	chr6	33672058	Missense_Mutation	rs779072484	V920M	0.24
UCEC	chr6	33655858	Missense_Mutation	rs766342194	A85T	0.47
UCEC	chr6	33696542	3'UTR	novel		0.59
UCEC	chr6	33665098	Missense_Mutation	NA	V432M	0.39
UCEC	chr6	33669142	Silent	novel	V725V	0.47
UCEC	chr6	33689381	Missense_Mutation	NA	P2280T	0.43
UCEC	chr6	33695826	3'UTR	novel		0.52
UCEC	chr6	33663868	Missense_Mutation	NA	S379Y	0.24
UCEC	chr6	33687504	Silent	NA	Q2068Q	0.57
UCEC	chr6	33677614	Missense_Mutation	novel	Q1211H	0.29
UCEC	chr6	33687091	Missense_Mutation	rs773891536	R2021Q	0.32
UCEC	chr6	33687305	Missense_Mutation	NA	N2052T	0.48
UCEC	chr6	33670737	Silent	rs2229635	F836F	0.47
UCEC	chr6	33671179	Silent	rs768456799	A867A	0.32
UCEC	chr6	33675732	Missense_Mutation	rs770956589	R1053H	0.21
UCEC	chr6	33687527	Missense_Mutation	NA	R2076H	0.41
UCEC	chr6	33659520	Missense_Mutation	rs760333138	R228W	0.33
UCEC	chr6	33677608	Silent	NA	L1209L	0.46
UCEC	chr6	33688721	Missense_Mutation	novel	A2212T	0.29
UCEC	chr6	33692794	Silent	rs375962763	L2509L	0.23
UCEC	chr6	33696400	3'UTR	novel		0.26
UCEC	chr6	33667859	Missense_Mutation	NA	T594I	0.38
UCEC	chr6	33675853	Silent	novel	K1093K	0.15
UCEC	chr6	33670498	Missense_Mutation	novel	R788H	0.37
UCEC	chr6	33663756	Missense_Mutation	novel	G342S	0.41
UCEC	chr6	33670520	Silent	rs774973210	T795T	0.23
UCEC	chr6	33685734	Silent	novel	V1858V	0.22
UCEC	chr6	33686063	Missense_Mutation	novel	R1893H	0.23
UCEC	chr6	33686194	Missense_Mutation	rs146844329	V1937I	0.32
UCEC	chr6	33691085	Missense_Mutation	rs370516286	R2401W	0.19
UCEC	chr6	33691886	Silent	rs750689163	N2472N	0.2
UCEC	chr6	33695101	Intron	novel		0.39
UCEC	chr6	33696569	3'UTR	novel		0.36
UCEC	chr6	33674249	Missense_Mutation	novel	A1034T	0.51
UCEC	chr6	33694955	Missense_Mutation	rs148037665	R2606Q	0.39
UCEC	chr6	33680096	Missense_Mutation	novel	V1396A	0.44
UCEC	chr6	33658712	Missense_Mutation	rs759577490	R138W	0.36
UCEC	chr6	33662624	Missense_Mutation	NA	R270C	0.33
UCEC	chr6	33676862	Missense_Mutation	NA	L1126P	0.24
UCEC	chr6	33687072	Nonsense_Mutation	rs763696426	R2015*	0.27
UCEC	chr6	33657968	Missense_Mutation	novel	E107K	0.41
UCEC	chr6	33663822	Missense_Mutation	rs749099428	A364T	0.45
UCEC	chr6	33667933	Missense_Mutation	rs773850087	V619I	0.34
UCEC	chr6	33668535	Missense_Mutation	novel	D636G	0.54
UCEC	chr6	33687048	Missense_Mutation	rs577534374	R2007W	0.42
UCEC	chr6	33688307	Silent	rs771212054	T2148T	0.45
UCEC	chr6	33693649	Missense_Mutation	rs780438879	V2577M	0.25
UCEC	chr6	33668572	Silent	novel	T648T	0.1
UCEC	chr6	33670455	Missense_Mutation	rs200526442	R774C	0.3
UCEC	chr6	33688135	Missense_Mutation	novel	A2115T	0.33
UCEC	chr6	33691700	Silent	rs113565114	S2437S	0.46
UCEC	chr6	33692779	Missense_Mutation	rs754218342	V2504I	0.35
UCEC	chr6	33691700	Silent	novel	S2437S	0.33
UCS	chr6	33662574	Missense_Mutation	novel	T253M	0.6
UVM	chr6	33687044	Silent	novel	E2005E	0.65

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value

Survival Analysis

Cancer	P-value	Q-value
ESCA	0.038	Kaplan-Meier Survival Analysis
PAAD	0.0067	Kaplan-Meier Survival Analysis
CESC	0.014	Kaplan-Meier Survival Analysis
READ	0.00022	Kaplan-Meier Survival Analysis
GBM	0.026	Kaplan-Meier Survival Analysis
LIHC	0.027	Kaplan-Meier Survival Analysis
LGG	0.02	Kaplan-Meier Survival Analysis
CHOL	0.027	Kaplan-Meier Survival Analysis
OV	0.029	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000096433 (Gene tree)
Gene ID: 3710
Gene Symbol: ITPR3
Alias: IP3R3
Full Name: inositol 1,4,5-trisphosphate receptor type 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 76,210 bases
Position: chr6:33,620,365-33,696,574
Accession: 6182
RBP type: non-canonical RBP
Summary: This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
30917677	Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (Kruppel-Like Factor 4)-Mediated Histone Modifications.	Arterioscler Thromb Vasc Biol	2019 May	He M	doi: 10.1161/ATVBAHA.118.312301.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000605930	ITPR3-202	9029	XM_011514577	ENSP00000475177	2671 (aa)	XP_011512879	Q14573
ENST00000374316	ITPR3-201	9870	-	ENSP00000363435	2671 (aa)	-	Q14573

Gene Model

Click here to download ENSG00000096433's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04020	Calcium signaling pathway	KEGG
hsa04022	cGMP-PKG signaling pathway	KEGG
hsa04070	Phosphatidylinositol signaling system	KEGG
hsa04114	Oocyte meiosis	KEGG
hsa04210	Apoptosis	KEGG
hsa04218	Cellular senescence	KEGG
hsa04270	Vascular smooth muscle contraction	KEGG
hsa04371	Apelin signaling pathway	KEGG
hsa04540	Gap junction	KEGG
hsa04611	Platelet activation	KEGG
hsa04621	NOD-like receptor signaling pathway	KEGG
hsa04625	C-type lectin receptor signaling pathway	KEGG
hsa04713	Circadian entrainment	KEGG
hsa04720	Long-term potentiation	KEGG
hsa04723	Retrograde endocannabinoid signaling	KEGG
hsa04724	Glutamatergic synapse	KEGG
hsa04725	Cholinergic synapse	KEGG
hsa04726	Serotonergic synapse	KEGG
hsa04728	Dopaminergic synapse	KEGG
hsa04730	Long-term depression	KEGG
hsa04742	Taste transduction	KEGG
hsa04750	Inflammatory mediator regulation of TRP channels	KEGG
hsa04911	Insulin secretion	KEGG
hsa04912	GnRH signaling pathway	KEGG
hsa04915	Estrogen signaling pathway	KEGG
hsa04918	Thyroid hormone synthesis	KEGG
hsa04921	Oxytocin signaling pathway	KEGG
hsa04922	Glucagon signaling pathway	KEGG
hsa04924	Renin secretion	KEGG
hsa04925	Aldosterone synthesis and secretion	KEGG
hsa04927	Cortisol synthesis and secretion	KEGG
hsa04928	Parathyroid hormone synthesis, secretion and action	KEGG
hsa04934	Cushing syndrome	KEGG
hsa04970	Salivary secretion	KEGG
hsa04971	Gastric acid secretion	KEGG
hsa04972	Pancreatic secretion	KEGG
hsa05010	Alzheimer disease	KEGG
hsa05163	Human cytomegalovirus infection	KEGG
hsa05167	Kaposi sarcoma-associated herpesvirus infection	KEGG
hsa05170	Human immunodeficiency virus 1 infection	KEGG
hsa05205	Proteoglycans in cancer	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000096433	Glucose	5.947e-005	19060910
ENSG00000096433	Platelet Function Tests	2.3600000E-005	-
ENSG00000096433	Body Height	3E-8	20881960
ENSG00000096433	Obesity	1E-6	19553259
ENSG00000096433	Schizophrenia	2E-6	26198764
ENSG00000096433	Venous Thromboembolism	5E-7	28203683
ENSG00000096433	Graves Disease	4E-12	21900946
ENSG00000096433	Education	3E-7	23722424

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000096433	rs4711336	6	33691269	?	Height	20881960	[NR]		EFO_0004339
ENSG00000096433	rs942637	6	33685334	?	Multiple sclerosis and body mass index (pleiotropy)	26920376	[1.0883-1.1837]		EFO_0003885\|EFO_0004340
ENSG00000096433	rs2296342	6	33659300	A	Schizophrenia	26198764	[NR]	1.05	EFO_0000692
ENSG00000096433	rs3227	6	33694518	C	Educational attainment	23722424	[NR]	1.037	EFO_0004784
ENSG00000096433	rs999943	6	33656956	T	Obesity (extreme)	19553259	[1.20-1.56]	1.37	EFO_0001073
ENSG00000096433	rs2229637	6	33675781	A	Venous thromboembolism adjusted for sickle cell variant rs77121243-T	28203683	[1.325-1.9]	1.587	EFO_0004286
ENSG00000096433	rs9394159	6	33650385	T	Graves' disease	21900946	[1.24-1.48]	1.36	EFO_0004237
ENSG00000096433	rs942642	6	33687120	T	Educational attainment (years of education)	30038396	[0.0059-0.0117] unit decrease	0.0088	EFO_0004784
ENSG00000096433	rs10807127	6	33651665	?	Red blood cell count	30595370			EFO_0004305
ENSG00000096433	rs10947428	6	33679281	?	Eczema	30595370			HP_0000964

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000096433's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.