EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29926841	POZ/BTB and AT-Hook-Containing Zinc Finger Protein 1 (PATZ1) Suppresses Progression of Ovarian Cancer and Serves as an Independent Prognosis Factor.	Med Sci Monit	2018 Jun 21	Zhao C	doi: 10.12659/MSM.908766.
18401526	Zinc finger protein 278, a potential oncogene in human colorectal cancer.	Acta Biochim Biophys Sin (Shanghai)	2008 Apr	Tian X	-
25595894	PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration.	Oncotarget	2015 Mar 10	Chiappetta G	-
27391343	PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer.	Oncotarget	2016 Aug 9	Ho MY	doi: 10.18632/oncotarget.10427.
29039562	Downregulation of ZNF278 arrests the cell cycle and decreases the proliferation of colorectal cancer cells via inhibition of the ERK/MAPK pathway.	Oncol Rep	2017 Dec	Tian XQ	doi: 10.3892/or.2017.6031

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr22	31345434	Missense_Mutation	novel	A57T	0.13
ACC	chr22	31344487	Silent	rs751106943	R372R	0.44
ACC	chr22	31345487	Missense_Mutation	novel	R39L	0.53
BLCA	chr22	31345471	Silent	novel	L44L	0.3
BLCA	chr22	31344809	Missense_Mutation	NA	R265Q	0.43
BLCA	chr22	31326994	Missense_Mutation	NA	S654Y	0.22
BLCA	chr22	31345113	Silent	novel	L164L	0.4
BLCA	chr22	31342922	Missense_Mutation	novel	T437I	0.08
BLCA	chr22	31341413	Intron	novel		0.35
BLCA	chr22	31326923	Missense_Mutation	novel	D678H	0.18
BLCA	chr22	31327215	Silent	novel	Q580Q	0.19
BLCA	chr22	31344618	Missense_Mutation	novel	P329A	0.51
BLCA	chr22	31327146	Silent	NA	K603K	0.05
BRCA	chr22	31335828	Silent	NA	L457L	0.5
BRCA	chr22	31344719	Missense_Mutation	novel	G295V	0.12
BRCA	chr22	31327054	Missense_Mutation	novel	G634D	0.09
CESC	chr22	31344587	Missense_Mutation	NA	S339C	0.12
CESC	chr22	31326883	3'UTR	rs200180132		0.33
CESC	chr22	31344400	Frame_Shift_Ins	novel	*H401Qfs6**	0.37
CESC	chr22	31345070	Frame_Shift_Del	NA	*P178Lfs12**	0.23
CESC	chr22	31341347	Intron	novel		0.33
CESC	chr22	31326499	3'UTR	novel		0.12
CESC	chr22	31326747	3'UTR	novel		0.31
CESC	chr22	31326444	3'UTR	novel		0.6
CESC	chr22	31344916	Silent	novel	L229L	0.23
CESC	chr22	31345143	Nonsense_Mutation	NA	E154*	0.24
CESC	chr22	31345296	Missense_Mutation	NA	E103Q	0.38
CESC	chr22	31347118	5'Flank	novel		0.81
CESC	chr22	31347024	5'Flank	novel		0.16
CHOL	chr22	31347060	5'Flank	novel		0.49
CHOL	chr22	31335694	Missense_Mutation	novel	R502Q	0.3	zf-C2H2
COAD	chr22	31341589	Intron	rs373917062		0.33
COAD	chr22	31326846	3'UTR	novel		0.3
COAD	chr22	31335826	Missense_Mutation	NA	R458H	0.11
COAD	chr22	31345276	Silent	rs140597902	I109I	0.44
COAD	chr22	31345001	Missense_Mutation	NA	G201D	0.14
COAD	chr22	31344720	Missense_Mutation	NA	G295C	0.27
COAD	chr22	31344539	Missense_Mutation	novel	V355G	0.31
COAD	chr22	31345070	Frame_Shift_Del	NA	*P178Lfs12**	0.47
COAD	chr22	31344749	Frame_Shift_Del	novel	*G285Pfs14**	0.11
DLBC	chr22	31345429	Silent	novel	V58V	0.13
ESCA	chr22	31341655	Intron	rs765835799		0.13
ESCA	chr22	31344481	Silent	novel	K374K	0.13
ESCA	chr22	31345164	Missense_Mutation	novel	S147T	0.22
ESCA	chr22	31328842	Missense_Mutation	novel	E530D	0.16
ESCA	chr22	31326503	3'UTR	novel		0.34
ESCA	chr22	31325821	3'UTR	novel		0.45
GBM	chr22	31345131	Frame_Shift_Ins	novel	*Q158Tfs142**	0.38
GBM	chr22	31328809	Silent	rs369406764	C541C	0.17
GBM	chr22	31328899	Silent	novel	K511K	0.44
GBM	chr22	31344587	Missense_Mutation	novel	S339F	0.11
GBM	chr22	31327056	Silent	novel	G633G	0.19
HNSC	chr22	31344938	Missense_Mutation	novel	G222V	0.36
HNSC	chr22	31335777	Silent	novel	G474G	0.06
HNSC	chr22	31344810	Nonsense_Mutation	NA	R265*	0.35
HNSC	chr22	31345076	Missense_Mutation	rs377660548	R176H	0.26
HNSC	chr22	31341647	Intron	novel		0.25
KIRP	chr22	31344795	Missense_Mutation	novel	P270T	0.46
LGG	chr22	31344752	Missense_Mutation	NA	G284E	0.25
LIHC	chr22	31344963	Missense_Mutation	novel	R214G	0.57
LUAD	chr22	31345559	Missense_Mutation	rs757918024	Y15C	0.42
LUAD	chr22	31345006	Silent	NA	S199S	0.38
LUAD	chr22	31327253	Missense_Mutation	novel	L568F	0.06
LUAD	chr22	31345095	Missense_Mutation	NA	A170P	0.18
LUAD	chr22	31345614	5'UTR	novel		0.72
LUAD	chr22	31326986	Missense_Mutation	NA	E657Q	0.09
LUAD	chr22	31345179	Missense_Mutation	NA	F142I	0.03
LUAD	chr22	31327001	Missense_Mutation	NA	N652Y	0.1
LUSC	chr22	31345314	Missense_Mutation	novel	G97R	0.19
LUSC	chr22	31328910	Frame_Shift_Ins	novel	*S508Vfs8**	0.27	zf-C2H2
LUSC	chr22	31328911	Frame_Shift_Ins	novel	*Y509Ffs13**	0.29	zf-C2H2
LUSC	chr22	31327053	Frame_Shift_Ins	novel	*L636Pfs41**	0.07
LUSC	chr22	31326902	Missense_Mutation	novel	E685Q	0.05
LUSC	chr22	31326892	Nonstop_Mutation	NA	688Sext30	0.33
LUSC	chr22	31327010	Missense_Mutation	NA	P649S	0.19
LUSC	chr22	31345336	Silent	NA	G89G	0.33
LUSC	chr22	31344809	Missense_Mutation	NA	R265Q	0.17
LUSC	chr22	31344969	Missense_Mutation	novel	A212S	0.18
OV	chr22	31344548	Missense_Mutation	novel	R352M	0.21
OV	chr22	31344549	Missense_Mutation	novel	R352W	0.19
OV	chr22	31341449	Intron	novel		0.19
OV	chr22	31341464	Intron	novel		0.49
OV	chr22	31335767	Missense_Mutation	rs768984900	R478W	0.53
OV	chr22	31344530	Missense_Mutation	novel	E358G	0.1
OV	chr22	31327192	Missense_Mutation	novel	C588Y	0.05
OV	chr22	31326766	3'UTR	novel		0.18
OV	chr22	31344531	Nonsense_Mutation	novel	E358*	0.16
OV	chr22	31327268	Missense_Mutation	novel	D563Y	0.06
PAAD	chr22	31335766	Missense_Mutation	rs749372022	R478Q	0.19
PRAD	chr22	31327238	Missense_Mutation	rs766392086	D573N	0.19
PRAD	chr22	31345070	Frame_Shift_Del	NA	*P178Lfs12**	0.17
PRAD	chr22	31335827	Missense_Mutation	NA	R458C	0.37
READ	chr22	31345168	Missense_Mutation	novel	M145I	0.07
READ	chr22	31327180	Missense_Mutation	NA	V592A	0.42
SARC	chr22	31344729	Missense_Mutation	novel	L292I	0.38
SARC	chr22	31344871	Silent	novel	P244P	0.32
SARC	chr22	31326557	3'UTR	novel		0.23
SARC	chr22	31344576	Missense_Mutation	novel	D343N	0.72
SKCM	chr22	31341381	Intron	novel		0.29
SKCM	chr22	31344407	Frame_Shift_Ins	novel	*S399Yfs11**	0.06
SKCM	chr22	31344409	Missense_Mutation	novel	M398I	0.01
SKCM	chr22	31328863	Silent	novel	P523P	0.27
SKCM	chr22	31328864	Missense_Mutation	novel	P523L	0.27
SKCM	chr22	31344828	Missense_Mutation	novel	P259S	0.33
SKCM	chr22	31344829	Silent	NA	A258A	0.29
SKCM	chr22	31326876	3'UTR	novel		0.12
SKCM	chr22	31341644	Intron	novel		0.11
SKCM	chr22	31345077	Missense_Mutation	NA	R176C	0.08
SKCM	chr22	31326994	Missense_Mutation	NA	S654F	0.33
SKCM	chr22	31344349	Silent	NA	C418C	0.24
SKCM	chr22	31326994	Missense_Mutation	NA	S654F	0.38
SKCM	chr22	31345183	Silent	NA	A140A	0.34
STAD	chr22	31345373	Missense_Mutation	novel	G77V	0.11
STAD	chr22	31345493	Missense_Mutation	NA	G37D	0.38
STAD	chr22	31345349	Missense_Mutation	NA	A85V	0.31
STAD	chr22	31341567	Intron	novel		0.38
STAD	chr22	31341275	Intron	novel		0.32
STAD	chr22	31327059	Silent	rs551643471	L632L	0.1
STAD	chr22	31335695	Nonsense_Mutation	novel	R502*	0.2	zf-C2H2
STAD	chr22	31335695	Nonsense_Mutation	novel	R502*	0.19	zf-C2H2
STAD	chr22	31345069	Frame_Shift_Ins	novel	*G179Wfs121**	0.21
STAD	chr22	31341432	Intron	novel		0.32
STAD	chr22	31341432	Intron	novel		0.27
STAD	chr22	31345308	Missense_Mutation	NA	G99R	0.09
STAD	chr22	31345418	Missense_Mutation	NA	C62Y	0.14
STAD	chr22	31341620	Intron	novel		0.12
STAD	chr22	31345335	Missense_Mutation	novel	A90S	0.09
STAD	chr22	31327068	Silent	rs139600326	V629V	0.19
STAD	chr22	31335827	Missense_Mutation	NA	R458C	0.38
UCEC	chr22	31335729	Silent	rs770233611	S490S	0.31
UCEC	chr22	31326784	3'UTR	novel		0.33
UCEC	chr22	31342957	Silent	rs770745510	P425P	0.42
UCEC	chr22	31326128	3'UTR	novel		0.38
UCEC	chr22	31326838	3'UTR	novel		0.23
UCEC	chr22	31328813	Missense_Mutation	NA	H540R	0.45
UCEC	chr22	31327270	Missense_Mutation	novel	S562F	0.37
UCEC	chr22	31341379	Intron	novel		0.33
UCEC	chr22	31335839	Nonsense_Mutation	novel	R454*	0.39
UCEC	chr22	31347140	5'Flank	novel		0.39
UCEC	chr22	31328837	Missense_Mutation	novel	I532T	0.18
UCEC	chr22	31344966	Missense_Mutation	novel	A213T	0.33
UCEC	chr22	31344370	Silent	NA	K411K	0.19
UCEC	chr22	31335719	Missense_Mutation	NA	S494G	0.35
UCEC	chr22	31326789	3'UTR	novel		0.43
UCEC	chr22	31326790	3'UTR	novel		0.36
UCEC	chr22	31341636	Intron	novel		0.41
UCEC	chr22	31327108	Missense_Mutation	NA	S616C	0.27
UCEC	chr22	31344612	Missense_Mutation	NA	L331V	0.39
UCEC	chr22	31344413	Missense_Mutation	novel	R397H	0.26
UCEC	chr22	31345412	Missense_Mutation	NA	E64G	0.3
UCEC	chr22	31325850	3'UTR	novel		0.22
UCEC	chr22	31341589	Intron	rs373917062		0.14
UCEC	chr22	31345316	Missense_Mutation	novel	G96D	0.2
UCEC	chr22	31346949	5'Flank	novel		0.24
UCEC	chr22	31326838	3'UTR	novel		0.48
UCEC	chr22	31345106	Missense_Mutation	novel	P166L	0.38
UCEC	chr22	31347095	5'Flank	novel		0.25
UCEC	chr22	31342962	Splice_Site	novel	X424_splice	0.47
UCEC	chr22	31344572	Missense_Mutation	novel	G344D	0.4
UCEC	chr22	31345260	Missense_Mutation	NA	G115W	0.29
UCEC	chr22	31326696	3'UTR	novel		0.3
UCEC	chr22	31341477	Intron	rs548611611		0.23
UCEC	chr22	31345255	Missense_Mutation	novel	D116E	0.19
UCEC	chr22	31341440	Intron	novel		0.41
UCEC	chr22	31327141	Missense_Mutation	NA	Y605C	0.3
UCEC	chr22	31347045	5'Flank	novel		0.09
UCEC	chr22	31345190	Missense_Mutation	novel	T138M	0.06
UCEC	chr22	31328920	Missense_Mutation	NA	F504L	0.32	zf-C2H2
UCEC	chr22	31326002	3'UTR	novel		0.35
UCEC	chr22	31335856	Missense_Mutation	rs759027914	N448S	0.28
UCEC	chr22	31344903	Missense_Mutation	novel	R234C	0.25
UCEC	chr22	31341491	Intron	novel		0.09
UCEC	chr22	31345021	Silent	novel	A194A	0.09
UCEC	chr22	31344688	Silent	novel	N305N	0.42
UCEC	chr22	31326716	3'UTR	novel		0.5
UCEC	chr22	31335729	Silent	rs770233611	S490S	0.45
UCEC	chr22	31344903	Missense_Mutation	novel	R234C	0.44

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.1569	0.00055806

Survival Analysis

Cancer	P-value	Q-value
THYM	0.027	Kaplan-Meier Survival Analysis
KIRC	0.00036	Kaplan-Meier Survival Analysis
LUSC	0.0079	Kaplan-Meier Survival Analysis
ESCA	0.03	Kaplan-Meier Survival Analysis
KIRP	0.012	Kaplan-Meier Survival Analysis
PAAD	0.00098	Kaplan-Meier Survival Analysis
BLCA	0.0001	Kaplan-Meier Survival Analysis
GBM	0.0029	Kaplan-Meier Survival Analysis
LIHC	0.032	Kaplan-Meier Survival Analysis
UVM	0.016	Kaplan-Meier Survival Analysis
OV	0.039	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000100105 (Gene tree)
Gene ID: 23598
Gene Symbol: PATZ1
Alias: MAZR|dJ400N23|ZBTB19|ZSG|RIAZ|PATZ|ZNF278
Full Name: POZ/BTB and AT hook containing zinc finger 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 20,460 bases
Position: chr22:31,325,804-31,346,263
Accession: 13071
RBP type: canonical RBP
Summary: The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000266269	zf-C2H2	PF00096.26	8.2e-26	1	5
ENSP00000266269	zf-C2H2	PF00096.26	8.2e-26	2	5
ENSP00000266269	zf-C2H2	PF00096.26	8.2e-26	3	5
ENSP00000266269	zf-C2H2	PF00096.26	8.2e-26	4	5
ENSP00000266269	zf-C2H2	PF00096.26	8.2e-26	5	5
ENSP00000337520	zf-C2H2	PF00096.26	1.6e-19	1	4
ENSP00000337520	zf-C2H2	PF00096.26	1.6e-19	2	4
ENSP00000337520	zf-C2H2	PF00096.26	1.6e-19	3	4
ENSP00000337520	zf-C2H2	PF00096.26	1.6e-19	4	4
ENSP00000384173	zf-C2H2	PF00096.26	3.9e-16	1	3
ENSP00000384173	zf-C2H2	PF00096.26	3.9e-16	2	3
ENSP00000384173	zf-C2H2	PF00096.26	3.9e-16	3	3
ENSP00000215919	zf-C2H2	PF00096.26	4.8e-15	1	3
ENSP00000215919	zf-C2H2	PF00096.26	4.8e-15	2	3
ENSP00000215919	zf-C2H2	PF00096.26	4.8e-15	3	3
ENSP00000266269	zf-met	PF12874.7	7.9e-11	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000494109	PATZ1-206	835	-	-	- (aa)	-	-
ENST00000465287	PATZ1-205	1702	-	-	- (aa)	-	-
ENST00000266269	PATZ1-202	3781	-	ENSP00000266269	687 (aa)	-	Q9HBE1
ENST00000215919	PATZ1-201	2516	-	ENSP00000215919	537 (aa)	-	Q9HBE1
ENST00000405309	PATZ1-204	3711	-	ENSP00000384173	537 (aa)	-	Q9HBE1
ENST00000351933	PATZ1-203	3638	-	ENSP00000337520	641 (aa)	-	Q9HBE1

Gene Model

Click here to download ENSG00000100105's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000100105	Platelet Function Tests	1.5013700E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000100105	rs572182531	22	31331345	CT	Reticulocyte count	27863252	[0.024-0.047] unit decrease	0.03581047	EFO_0007986
ENSG00000100105	rs572182531	22	31331345	CT	Reticulocyte fraction of red cells	27863252	[0.024-0.047] unit decrease	0.035843	EFO_0007986
ENSG00000100105	rs28715	22	31334183	T	Red cell distribution width	28957414	[0.016-0.031] unit increase	0.0235931	EFO_0005192
ENSG00000100105	rs140074	22	31329648	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000100105's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000100105	PATZ1	99	60.038	ENSAPOG00000018447	patz1	100	59.240	Acanthochromis_polyacanthus
ENSG00000100105	PATZ1	100	99.127	ENSAMEG00000007074	PATZ1	100	99.127	Ailuropoda_melanoleuca
ENSG00000100105	PATZ1	100	60.232	ENSACIG00000016779	patz1	100	59.961	Amphilophus_citrinellus
ENSG00000100105	PATZ1	100	57.563	ENSAPEG00000013354	patz1	100	57.703	Amphiprion_percula
ENSG00000100105	PATZ1	100	62.549	ENSATEG00000011260	patz1	100	62.353	Anabas_testudineus
ENSG00000100105	PATZ1	85	91.267	ENSAPLG00000003934	PATZ1	99	91.096	Anas_platyrhynchos
ENSG00000100105	PATZ1	100	100.000	ENSANAG00000029603	PATZ1	100	100.000	Aotus_nancymaae
ENSG00000100105	PATZ1	97	62.524	ENSAMXG00000002273	patz1	98	62.147	Astyanax_mexicanus
ENSG00000100105	PATZ1	100	99.220	ENSBTAG00000005478	PATZ1	100	99.220	Bos_taurus
ENSG00000100105	PATZ1	100	100.000	ENSCJAG00000010978	PATZ1	100	100.000	Callithrix_jacchus
ENSG00000100105	PATZ1	100	99.376	ENSCAFG00000013087	PATZ1	100	99.272	Canis_familiaris
ENSG00000100105	PATZ1	100	98.752	ENSCHIG00000020203	PATZ1	100	98.752	Capra_hircus
ENSG00000100105	PATZ1	100	99.532	ENSTSYG00000033183	PATZ1	100	99.532	Carlito_syrichta
ENSG00000100105	PATZ1	100	100.000	ENSCCAG00000028772	PATZ1	100	100.000	Cebus_capucinus
ENSG00000100105	PATZ1	100	99.709	ENSCATG00000006101	PATZ1	100	99.709	Cercocebus_atys
ENSG00000100105	PATZ1	100	88.986	ENSCPBG00000011277	PATZ1	100	89.130	Chrysemys_picta_bellii
ENSG00000100105	PATZ1	100	99.709	ENSCANG00000024972	PATZ1	100	99.709	Colobus_angolensis_palliatus
ENSG00000100105	PATZ1	100	97.234	ENSCGRG00001004071	Patz1	100	97.234	Cricetulus_griseus_chok1gshd
ENSG00000100105	PATZ1	93	97.978	ENSCGRG00000004814	Patz1	100	97.978	Cricetulus_griseus_crigri
ENSG00000100105	PATZ1	100	55.307	ENSCSEG00000001385	patz1	100	55.278	Cynoglossus_semilaevis
ENSG00000100105	PATZ1	100	58.997	ENSCVAG00000007684	patz1	100	59.292	Cyprinodon_variegatus
ENSG00000100105	PATZ1	97	60.679	ENSDARG00000076584	patz1	98	58.511	Danio_rerio
ENSG00000100105	PATZ1	97	95.611	ENSDNOG00000003183	PATZ1	100	98.546	Dasypus_novemcinctus
ENSG00000100105	PATZ1	100	99.376	ENSDORG00000023834	Patz1	100	99.376	Dipodomys_ordii
ENSG00000100105	PATZ1	100	99.220	ENSECAG00000025030	PATZ1	100	99.220	Equus_caballus
ENSG00000100105	PATZ1	99	61.887	ENSELUG00000002333	patz1	100	58.166	Esox_lucius
ENSG00000100105	PATZ1	100	99.376	ENSFCAG00000030253	PATZ1	100	99.376	Felis_catus
ENSG00000100105	PATZ1	86	91.525	ENSFALG00000007450	PATZ1	99	91.482	Ficedula_albicollis
ENSG00000100105	PATZ1	96	98.051	ENSFDAG00000005614	PATZ1	100	98.051	Fukomys_damarensis
ENSG00000100105	PATZ1	100	57.918	ENSFHEG00000014755	patz1	100	57.625	Fundulus_heteroclitus
ENSG00000100105	PATZ1	98	55.091	ENSGMOG00000001062	patz1	98	54.848	Gadus_morhua
ENSG00000100105	PATZ1	100	88.345	ENSGALG00000006934	PATZ1	100	88.489	Gallus_gallus
ENSG00000100105	PATZ1	100	59.029	ENSGAFG00000010053	patz1	100	57.856	Gambusia_affinis
ENSG00000100105	PATZ1	85	91.938	ENSGAGG00000003214	PATZ1	100	91.767	Gopherus_agassizii
ENSG00000100105	PATZ1	100	99.854	ENSGGOG00000017171	PATZ1	100	99.854	Gorilla_gorilla
ENSG00000100105	PATZ1	98	62.846	ENSHCOG00000017644	patz1	98	61.372	Hippocampus_comes
ENSG00000100105	PATZ1	97	60.285	ENSIPUG00000017653	patz1	97	53.748	Ictalurus_punctatus
ENSG00000100105	PATZ1	100	99.127	ENSSTOG00000020707	PATZ1	100	99.127	Ictidomys_tridecemlineatus
ENSG00000100105	PATZ1	100	96.807	ENSJJAG00000015259	Patz1	100	96.807	Jaculus_jaculus
ENSG00000100105	PATZ1	100	57.670	ENSKMAG00000008157	patz1	100	57.627	Kryptolebias_marmoratus
ENSG00000100105	PATZ1	100	98.544	ENSLAFG00000002317	PATZ1	100	98.544	Loxodonta_africana
ENSG00000100105	PATZ1	100	99.563	ENSMFAG00000040968	PATZ1	100	99.563	Macaca_fascicularis
ENSG00000100105	PATZ1	100	99.563	ENSMNEG00000037588	PATZ1	100	99.563	Macaca_nemestrina
ENSG00000100105	PATZ1	100	99.709	ENSMLEG00000030938	PATZ1	100	99.709	Mandrillus_leucophaeus
ENSG00000100105	PATZ1	100	57.625	ENSMAMG00000023652	patz1	100	57.771	Mastacembelus_armatus
ENSG00000100105	PATZ1	85	87.692	ENSMGAG00000008439	PATZ1	100	87.521	Meleagris_gallopavo
ENSG00000100105	PATZ1	100	98.981	ENSMAUG00000004129	Patz1	100	98.981	Mesocricetus_auratus
ENSG00000100105	PATZ1	100	99.532	ENSMICG00000005430	PATZ1	100	99.532	Microcebus_murinus
ENSG00000100105	PATZ1	100	98.836	ENSMOCG00000014488	Patz1	100	98.836	Microtus_ochrogaster
ENSG00000100105	PATZ1	99	55.469	ENSMMOG00000021679	patz1	100	48.656	Mola_mola
ENSG00000100105	PATZ1	100	56.941	ENSMALG00000021172	patz1	100	56.657	Monopterus_albus
ENSG00000100105	PATZ1	100	98.883	MGP_CAROLIEiJ_G0016007	Patz1	100	98.883	Mus_caroli
ENSG00000100105	PATZ1	100	98.981	ENSMUSG00000020453	Patz1	100	98.981	Mus_musculus
ENSG00000100105	PATZ1	100	98.981	MGP_PahariEiJ_G0016884	Patz1	100	98.981	Mus_pahari
ENSG00000100105	PATZ1	100	98.981	MGP_SPRETEiJ_G0016846	Patz1	100	98.981	Mus_spretus
ENSG00000100105	PATZ1	100	99.064	ENSMLUG00000009942	PATZ1	100	99.064	Myotis_lucifugus
ENSG00000100105	PATZ1	100	99.272	ENSNGAG00000010268	Patz1	100	99.272	Nannospalax_galili
ENSG00000100105	PATZ1	100	60.039	ENSNBRG00000016032	patz1	100	59.768	Neolamprologus_brichardi
ENSG00000100105	PATZ1	68	93.978	ENSMEUG00000016293	PATZ1	99	93.966	Notamacropus_eugenii
ENSG00000100105	PATZ1	100	98.752	ENSODEG00000003589	PATZ1	100	98.752	Octodon_degus
ENSG00000100105	PATZ1	100	58.918	ENSONIG00000004248	patz1	100	58.712	Oreochromis_niloticus
ENSG00000100105	PATZ1	100	93.179	ENSOANG00000014654	PATZ1	100	93.469	Ornithorhynchus_anatinus
ENSG00000100105	PATZ1	100	58.779	ENSORLG00020010937	patz1	100	58.626	Oryzias_latipes_hni
ENSG00000100105	PATZ1	100	58.150	ENSORLG00015007396	patz1	100	58.003	Oryzias_latipes_hsok
ENSG00000100105	PATZ1	100	57.459	ENSOMEG00000006636	patz1	100	57.459	Oryzias_melastigma
ENSG00000100105	PATZ1	100	99.272	ENSOGAG00000027905	PATZ1	100	99.272	Otolemur_garnettii
ENSG00000100105	PATZ1	100	99.854	ENSPPAG00000033227	PATZ1	100	99.854	Pan_paniscus
ENSG00000100105	PATZ1	100	99.376	ENSPPRG00000001573	PATZ1	100	99.376	Panthera_pardus
ENSG00000100105	PATZ1	86	99.325	ENSPTIG00000007937	PATZ1	91	99.325	Panthera_tigris_altaica
ENSG00000100105	PATZ1	100	99.854	ENSPTRG00000014268	PATZ1	100	99.854	Pan_troglodytes
ENSG00000100105	PATZ1	100	99.709	ENSPANG00000006821	PATZ1	100	99.709	Papio_anubis
ENSG00000100105	PATZ1	100	62.313	ENSPKIG00000019584	patz1	100	61.567	Paramormyrops_kingsleyae
ENSG00000100105	PATZ1	71	79.275	ENSPSIG00000016553	-	91	82.809	Pelodiscus_sinensis
ENSG00000100105	PATZ1	58	95.960	ENSPSIG00000011562	-	100	96.571	Pelodiscus_sinensis
ENSG00000100105	PATZ1	100	57.022	ENSPMGG00000010196	patz1	100	57.022	Periophthalmus_magnuspinnatus
ENSG00000100105	PATZ1	100	98.908	ENSPEMG00000005321	Patz1	100	98.908	Peromyscus_maniculatus_bairdii
ENSG00000100105	PATZ1	100	57.478	ENSPLAG00000010425	patz1	100	57.625	Poecilia_latipinna
ENSG00000100105	PATZ1	100	57.562	ENSPMEG00000000255	patz1	100	57.709	Poecilia_mexicana
ENSG00000100105	PATZ1	100	57.044	ENSPREG00000002440	patz1	100	57.182	Poecilia_reticulata
ENSG00000100105	PATZ1	100	99.563	ENSPPYG00000011732	PATZ1	100	99.563	Pongo_abelii
ENSG00000100105	PATZ1	100	99.376	ENSPCOG00000019729	PATZ1	100	99.376	Propithecus_coquereli
ENSG00000100105	PATZ1	100	99.418	ENSPVAG00000001749	PATZ1	100	99.418	Pteropus_vampyrus
ENSG00000100105	PATZ1	100	59.244	ENSPNYG00000013542	patz1	100	58.906	Pundamilia_nyererei
ENSG00000100105	PATZ1	84	60.454	ENSPNAG00000017222	patz1	99	59.486	Pygocentrus_nattereri
ENSG00000100105	PATZ1	100	99.709	ENSRBIG00000044231	PATZ1	100	99.709	Rhinopithecus_bieti
ENSG00000100105	PATZ1	100	99.709	ENSRROG00000037155	PATZ1	100	99.709	Rhinopithecus_roxellana
ENSG00000100105	PATZ1	100	100.000	ENSSBOG00000003894	PATZ1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000100105	PATZ1	79	88.462	ENSSFOG00015013244	patz1	78	88.462	Scleropages_formosus
ENSG00000100105	PATZ1	100	87.055	ENSSPUG00000015298	PATZ1	100	86.629	Sphenodon_punctatus
ENSG00000100105	PATZ1	85	98.797	ENSSSCG00000010027	PATZ1	100	98.881	Sus_scrofa
ENSG00000100105	PATZ1	100	58.264	ENSTRUG00000015366	patz1	100	57.676	Takifugu_rubripes
ENSG00000100105	PATZ1	100	99.127	ENSTTRG00000010279	PATZ1	100	99.127	Tursiops_truncatus
ENSG00000100105	PATZ1	100	99.376	ENSUAMG00000015014	PATZ1	100	99.376	Ursus_americanus
ENSG00000100105	PATZ1	100	73.043	ENSXETG00000004190	patz1	100	72.319	Xenopus_tropicalis
ENSG00000100105	PATZ1	100	57.856	ENSXMAG00000015531	patz1	100	58.003	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	-	IEA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	ISM	Function
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	-	IEA	Function
GO:0003677	DNA binding	10949935.	NAS	Function
GO:0003682	chromatin binding	-	IEA	Function
GO:0005634	nucleus	10713105.	TAS	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0006355	regulation of transcription, DNA-templated	10713105.	TAS	Process
GO:0007283	spermatogenesis	-	IEA	Process
GO:0008584	male gonad development	-	IEA	Process
GO:0030217	T cell differentiation	-	IEA	Process
GO:0045892	negative regulation of transcription, DNA-templated	10713105.	TAS	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.