EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21533124	MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer.	PLoS One	2011 Apr 18	Liang S	doi: 10.1371/journal.pone.0018409.
27350172	DT-13 inhibits cancer cell migration by regulating NMIIA indirectly in the tumor microenvironment.	Oncol Rep	2016 Aug	Du H	doi: 10.3892/or.2016.4890
28900514	MicroRNA-647 Targets SRF-MYH9 Axis to Suppress Invasion and Metastasis of Gastric Cancer.	Theranostics	2017 Aug 2	Ye G	doi: 10.7150/thno.20512
24596217	MYH9 regulates p53 stability and is a tumor suppressor in SCC.	Cancer Discov	2014 Mar	-	doi: 10.1158/2159-8290.CD-RW2014-023
24468067	Myosin IIa activation is crucial in breast cancer derived galectin-1 mediated tolerogenic dendritic cell differentiation.	Biochim Biophys Acta	2014 Jun	Cheng DE	doi: 10.1016/j.bbagen.2014.01.026
28160562	The tumor suppressor capability of p53 is dependent on non-muscle myosin IIA function in head and neck cancer.	Oncotarget	2017 Apr 4	Coaxum SD	doi: 10.18632/oncotarget.14967.
21951916	Nonmuscle myosin IIA is associated with poor prognosis of esophageal squamous cancer.	Dis Esophagus	2012 Jul	Xia ZK	doi: 10.1111/j.1442-2050.2011.01261.x
22895805	Non-muscle myosin II is an independent predictor of overall survival for cystectomy candidates with early-stage bladder cancer.	Oncol Rep	2012 Nov	Xiong D	doi: 10.3892/or.2012.1965
26719067	Downregulation of nonmuscle myosin IIA expression inhibits migration and invasion of gastric cancer cells via the cJun Nterminal kinase signaling pathway.	Mol Med Rep	2016 Feb	Liu T	doi: 10.3892/mmr.2015.4742
21805244	Identification of the myosin heavy polypeptide 9 as a downstream effector of the proprotein convertases in the human colon carcinoma HT-29 cells.	Methods Mol Biol	2011	Scamuffa N	doi: 10.1007/978-1-61779-204-5_10.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr22	36304089	Missense_Mutation	rs757850500	G766S	0.18
BLCA	chr22	36321764	Missense_Mutation	novel	E255K	0.2
BLCA	chr22	36349207	Silent	novel	L10L	0.33
BLCA	chr22	36286738	Missense_Mutation	novel	E1681K	0.59
BLCA	chr22	36288836	Missense_Mutation	novel	A1554V	0.06
BLCA	chr22	36284463	Silent	rs774510520	L1844L	0.19
BLCA	chr22	36284431	Missense_Mutation	rs746568745	R1855Q	0.39
BLCA	chr22	36298965	Silent	rs766890055	L1018L	0.26
BLCA	chr22	36289295	Splice_Region	novel	L1449L	0.32
BLCA	chr22	36284233	Silent	novel	L1875L	0.08
BLCA	chr22	36304071	Missense_Mutation	novel	E772K	0.23
BLCA	chr22	36319586	Silent	NA	F354F	0.33
BLCA	chr22	36318284	Missense_Mutation	rs767088377	D384N	0.16
BLCA	chr22	36320221	Missense_Mutation	novel	M337I	0.21
BLCA	chr22	36349209	Missense_Mutation	NA	L10V	0.24
BLCA	chr22	36349128	Missense_Mutation	NA	D37H	0.43
BLCA	chr22	36295599	Missense_Mutation	novel	E1131Q	0.2
BLCA	chr22	36312186	Nonsense_Mutation	novel	E531*	0.42
BLCA	chr22	36288784	Silent	NA	R1571R	0.14
BLCA	chr22	36298956	Silent	novel	L1021L	0.21
BLCA	chr22	36293385	Missense_Mutation	rs765101192	E1347K	0.23
BLCA	chr22	36314316	Splice_Region	novel	L461L	0.11
BLCA	chr22	36314229	Missense_Mutation	novel	E490D	0.06
BLCA	chr22	36312204	Missense_Mutation	NA	L525V	0.08
BLCA	chr22	36302574	Silent	NA	F831F	0.14
BLCA	chr22	36322512	Missense_Mutation	novel	E208K	0.35
BLCA	chr22	36294967	Nonsense_Mutation	novel	E1199*	0.28
BLCA	chr22	36285228	Silent	NA	V1792V	0.22
BLCA	chr22	36284208	Missense_Mutation	novel	E1884Q	0.09
BLCA	chr22	36285311	Missense_Mutation	rs779971012	D1765N	0.23
BLCA	chr22	36285297	Missense_Mutation	novel	E1769D	0.3
BLCA	chr22	36349189	Silent	novel	F16F	0.3
BLCA	chr22	36312147	Nonsense_Mutation	novel	E544*	0.65
BLCA	chr22	36312148	Silent	novel	V543V	0.64
BLCA	chr22	36301536	Nonsense_Mutation	NA	Q877*	0.27
BLCA	chr22	36285326	Missense_Mutation	novel	D1760Y	0.4
BLCA	chr22	36300946	Missense_Mutation	NA	E915K	0.41
BLCA	chr22	36301592	Missense_Mutation	NA	R858T	0.74
BLCA	chr22	36304137	Missense_Mutation	NA	D750H	0.8
BLCA	chr22	36294938	Silent	rs540687260	T1208T	0.29
BLCA	chr22	36285711	Nonsense_Mutation	novel	E1741*	0.59
BLCA	chr22	36292060	Missense_Mutation	rs80338831	D1424N	0.42
BLCA	chr22	36286738	Missense_Mutation	novel	E1681K	0.2
BLCA	chr22	36348917	Nonsense_Mutation	NA	S107*	0.36
BRCA	chr22	36298930	Missense_Mutation	novel	T1030I	0.34
BRCA	chr22	36304095	Missense_Mutation	NA	R764C	0.35
BRCA	chr22	36341481	Silent	NA	L127L	0.24
BRCA	chr22	36284404	Missense_Mutation	NA	Q1864P	0.41
BRCA	chr22	36302662	Missense_Mutation	NA	R802L	0.44
BRCA	chr22	36348916	Frame_Shift_Del	novel	*K82Gfs54**	0.07
BRCA	chr22	36312212	Missense_Mutation	NA	P522L	0.31
BRCA	chr22	36301031	Splice_Site	novel	X878_splice	0.18
BRCA	chr22	36294185	Silent	NA	K1248K	0.28
BRCA	chr22	36348963	Missense_Mutation	NA	L92V	0.16
BRCA	chr22	36298988	Missense_Mutation	novel	E1011Q	0.05
BRCA	chr22	36298959	Frame_Shift_Del	NA	*K1020Nfs9**	0.26
BRCA	chr22	36300860	Missense_Mutation	novel	Q943H	0.27
BRCA	chr22	36285906	Silent	NA	R1703R	0.47
BRCA	chr22	36312059	Missense_Mutation	novel	Y573C	0.08
BRCA	chr22	36306536	Missense_Mutation	novel	R639W	0.11
BRCA	chr22	36301561	Silent	NA	L868L	0.35
BRCA	chr22	36312189	Missense_Mutation	NA	E530K	0.24
BRCA	chr22	36314306	Missense_Mutation	NA	E465Q	0.22
BRCA	chr22	36305086	Missense_Mutation	novel	P726S	0.25
BRCA	chr22	36300953	Missense_Mutation	NA	E912D	0.37
BRCA	chr22	36288906	Nonsense_Mutation	NA	E1531*	0.33
BRCA	chr22	36319609	Missense_Mutation	NA	L347F	0.08
BRCA	chr22	36295649	Missense_Mutation	NA	S1114C	0.31
BRCA	chr22	36348957	Missense_Mutation	NA	E94K	0.32
BRCA	chr22	36305041	Missense_Mutation	rs140032888	V741M	0.21
BRCA	chr22	36314207	Missense_Mutation	NA	E498K	0.3
BRCA	chr22	36284226	Nonsense_Mutation	NA	Q1878*	0.32
BRCA	chr22	36284255	Frame_Shift_Del	novel	*A1868Dfs5**	0.17
BRCA	chr22	36322426	Splice_Region	rs779192250		0.62
BRCA	chr22	36298933	Missense_Mutation	NA	I1029T	0.12
BRCA	chr22	36326637	Silent	rs146514663	T181T	0.45
BRCA	chr22	36293822	Silent	NA	D1293D	0.2
BRCA	chr22	36286804	Missense_Mutation	rs371410108	A1659T	0.42
BRCA	chr22	36295636	Frame_Shift_Del	novel	*S1111Tfs23**	0.88
BRCA	chr22	36312189	Missense_Mutation	NA	E530K	0.36
CESC	chr22	36288281	Missense_Mutation	NA	E1635K	0.1
CESC	chr22	36300941	Silent	novel	I916I	0.09
CESC	chr22	36306527	In_Frame_Del	novel	K637_G641del	0.09
CESC	chr22	36293372	In_Frame_Ins	novel	E1350dup	0.36
CESC	chr22	36288383	Nonsense_Mutation	NA	E1601*	0.28
CESC	chr22	36314279	Missense_Mutation	NA	E474Q	0.22
CESC	chr22	36286819	Missense_Mutation	NA	L1654M	0.27
CESC	chr22	36312189	Missense_Mutation	NA	E530K	0.21
CESC	chr22	36309314	Missense_Mutation	NA	S604F	0.39
CESC	chr22	36321797	Missense_Mutation	NA	D244N	0.31
CESC	chr22	36281409	3'UTR	novel		0.21
CESC	chr22	36294089	Splice_Region	novel		0.51
CESC	chr22	36316630	Missense_Mutation	NA	E423K	0.23
CESC	chr22	36322471	Silent	rs375965637	F221F	0.14
CESC	chr22	36301689	Intron	NA		0.54
CESC	chr22	36281811	3'UTR	novel		0.39
CESC	chr22	36282023	3'UTR	novel		0.43
CESC	chr22	36295681	Silent	NA	L1103L	0.35
CESC	chr22	36304051	Missense_Mutation	novel	K778N	0.3
CESC	chr22	36304071	Missense_Mutation	novel	E772K	0.26
CESC	chr22	36295542	Missense_Mutation	NA	D1150Y	0.23
CESC	chr22	36295718	Splice_Site	NA	X1091_splice	0.37
CESC	chr22	36300171	Missense_Mutation	NA	E978Q	0.21
CESC	chr22	36348917	Nonsense_Mutation	NA	S107*	0.22
CESC	chr22	36349139	Nonsense_Mutation	NA	W33*	0.25
CESC	chr22	36289160	Silent	NA	E1494E	0.18
CESC	chr22	36284242	Silent	NA	L1872L	0.47
CHOL	chr22	36321822	Splice_Site	novel	X236_splice	0.38
COAD	chr22	36292110	Missense_Mutation	NA	A1407V	0.19
COAD	chr22	36304080	Missense_Mutation	NA	A769T	0.25
COAD	chr22	36284436	Silent	rs775990931	D1853D	0.42
COAD	chr22	36284123	Missense_Mutation	NA	R1912H	0.39
COAD	chr22	36322451	Missense_Mutation	rs772134801	K228R	0.3
COAD	chr22	36294943	Nonsense_Mutation	NA	Q1207*	0.37
COAD	chr22	36288826	Silent	novel	R1557R	0.1
COAD	chr22	36285738	Missense_Mutation	novel	A1732T	0.34
COAD	chr22	36288820	Silent	novel	E1559E	0.27
COAD	chr22	36325051	Intron	novel		0.38
COAD	chr22	36284501	Missense_Mutation	novel	A1832T	0.33
COAD	chr22	36299037	Missense_Mutation	novel	K994N	0.35
COAD	chr22	36285290	Missense_Mutation	novel	H1772N	0.37
COAD	chr22	36305928	Splice_Site	novel	X720_splice	0.27
COAD	chr22	36293807	Silent	NA	K1298K	0.22
COAD	chr22	36304036	Frame_Shift_Del	novel	I784*	0.07
COAD	chr22	36285926	Missense_Mutation	rs372871106	R1697C	0.4
COAD	chr22	36292024	Missense_Mutation	rs373912645	A1436T	0.25
COAD	chr22	36296901	Missense_Mutation	rs532156048	A1072T	0.27
COAD	chr22	36282691	Missense_Mutation	NA	A1954T	0.36
COAD	chr22	36288905	Missense_Mutation	NA	E1531V	0.25
COAD	chr22	36349061	Missense_Mutation	NA	V59A	0.37
COAD	chr22	36286804	Missense_Mutation	rs371410108	A1659T	0.36
COAD	chr22	36326596	Missense_Mutation	NA	A195V	0.28
COAD	chr22	36292024	Missense_Mutation	rs373912645	A1436T	0.48
COAD	chr22	36284263	Splice_Region	rs764367941	A1865A	0.33
COAD	chr22	36288853	Silent	rs765280741	L1548L	0.34
COAD	chr22	36322428	Splice_Site	NA	X235_splice	0.22
COAD	chr22	36320364	Splice_Site	NA	X290_splice	0.27
COAD	chr22	36284422	Missense_Mutation	novel	A1858V	0.56
COAD	chr22	36284449	Missense_Mutation	NA	L1849P	0.56
COAD	chr22	36293787	Missense_Mutation	rs141904682	A1305V	0.29
COAD	chr22	36314177	Missense_Mutation	novel	L508M	0.34
COAD	chr22	36320330	Missense_Mutation	novel	R301H	0.36
COAD	chr22	36316518	Missense_Mutation	novel	D460G	0.25
COAD	chr22	36294300	Splice_Site	novel	X1211_splice	0.36
COAD	chr22	36293820	Missense_Mutation	NA	S1294N	0.45
COAD	chr22	36302568	Missense_Mutation	novel	K833N	0.14
COAD	chr22	36349212	Missense_Mutation	NA	Y9H	0.44
COAD	chr22	36316617	Missense_Mutation	rs760489771	R427H	0.26
COAD	chr22	36318256	Missense_Mutation	rs202023656	R393H	0.22
COAD	chr22	36348965	Missense_Mutation	NA	C91Y	0.25
COAD	chr22	36322519	Splice_Region	rs139466141	G205G	0.39
COAD	chr22	36341392	Silent	rs727503293	T156T	0.36
COAD	chr22	36301009	Missense_Mutation	NA	E894K	0.52
COAD	chr22	36318256	Missense_Mutation	rs202023656	R393H	0.3
COAD	chr22	36319559	Silent	rs768508765	A363A	0.42
COAD	chr22	36305932	Splice_Region	novel	Q719Q	0.45
COAD	chr22	36348927	Missense_Mutation	novel	R104C	0.17
COAD	chr22	36294132	Missense_Mutation	rs375738970	R1266H	0.23
COAD	chr22	36320343	Missense_Mutation	novel	Y297H	0.08
COAD	chr22	36326595	Silent	rs374395918	A195A	0.28
COAD	chr22	36305045	Silent	novel	A739A	0.27
COAD	chr22	36300915	Missense_Mutation	NA	E925V	0.27
COAD	chr22	36319559	Silent	rs768508765	A363A	0.45
COAD	chr22	36316594	In_Frame_Ins	novel	N434_K435insD	0.07
COAD	chr22	36316595	Missense_Mutation	novel	N434K	0.07
COAD	chr22	36305973	Nonsense_Mutation	novel	Q706*	0.11
COAD	chr22	36285758	Missense_Mutation	NA	R1725Q	0.44
COAD	chr22	36297005	Missense_Mutation	novel	R1037H	0.14
COAD	chr22	36300867	In_Frame_Ins	NA	K940dup	0.52
ESCA	chr22	36288384	Silent	rs201223994	D1600D	0.16
ESCA	chr22	36289290	Missense_Mutation	rs759107183	A1451V	0.23
ESCA	chr22	36304090	Silent	novel	A765A	0.27
ESCA	chr22	36294128	Silent	novel	V1267V	0.43
ESCA	chr22	36282033	3'UTR	novel		0.07
ESCA	chr22	36281381	3'UTR	novel		0.27
ESCA	chr22	36289149	Missense_Mutation	novel	L1498R	0.71
GBM	chr22	36318284	Missense_Mutation	rs767088377	D384N	0.41
GBM	chr22	36293346	Missense_Mutation	rs569649580	A1360T	0.51
GBM	chr22	36285322	Missense_Mutation	novel	Q1761L	0.07
GBM	chr22	36294100	Nonsense_Mutation	novel	K1277*	0.2
GBM	chr22	36304120	Silent	novel	R755R	0.35
GBM	chr22	36288257	Silent	novel	L1643L	0.49
GBM	chr22	36292228	Missense_Mutation	novel	D1368N	0.46
GBM	chr22	36298964	Missense_Mutation	rs566644790	A1019T	0.24
GBM	chr22	36306459	Silent	rs202125487	T664T	0.43
GBM	chr22	36320879	Missense_Mutation	NA	R263C	0.24
GBM	chr22	36349253	Splice_Region	rs540581219		0.17
GBM	chr22	36286779	Missense_Mutation	novel	Q1667L	0.19
GBM	chr22	36292154	Missense_Mutation	novel	K1392N	0.38
GBM	chr22	36294937	Missense_Mutation	novel	K1209E	0.05
GBM	chr22	36301535	Missense_Mutation	novel	Q877R	0.15
GBM	chr22	36304030	Silent	novel	G785G	0.09
GBM	chr22	36300135	Silent	NA	L990L	0.21
GBM	chr22	36318282	Missense_Mutation	novel	D384E	0.13
HNSC	chr22	36305078	Silent	novel	S728S	0.32
HNSC	chr22	36306003	Missense_Mutation	novel	G696S	0.24
HNSC	chr22	36312189	Missense_Mutation	NA	E530K	0.27
HNSC	chr22	36316528	Missense_Mutation	NA	E457K	0.27
HNSC	chr22	36293373	Missense_Mutation	novel	A1351P	0.35
HNSC	chr22	36292004	Frame_Shift_Del	novel	*K1442Nfs69**	0.21
HNSC	chr22	36292005	Missense_Mutation	novel	K1442T	0.21
HNSC	chr22	36295598	Missense_Mutation	novel	E1131V	0.28
HNSC	chr22	36295599	Missense_Mutation	novel	E1131K	0.29
HNSC	chr22	36326644	Missense_Mutation	novel	G179D	0.32
HNSC	chr22	36312078	Missense_Mutation	novel	D567N	0.48
HNSC	chr22	36282658	3'UTR	novel		0.1
HNSC	chr22	36312189	Missense_Mutation	NA	E530K	0.16
HNSC	chr22	36327464	Frame_Shift_Ins	novel	*C172Lfs4**	0.14
HNSC	chr22	36316528	Missense_Mutation	NA	E457K	0.29
HNSC	chr22	36289169	Silent	novel	Q1491Q	0.28
HNSC	chr22	36312109	Silent	novel	F556F	0.09
HNSC	chr22	36312212	Missense_Mutation	NA	P522L	0.27
HNSC	chr22	36312189	Missense_Mutation	NA	E530K	0.26
HNSC	chr22	36305954	Missense_Mutation	novel	V712E	0.38
HNSC	chr22	36288330	Silent	novel	D1618D	0.26
HNSC	chr22	36289188	Missense_Mutation	novel	L1485P	0.35
HNSC	chr22	36349099	Silent	novel	L46L	0.2
HNSC	chr22	36349207	Silent	novel	L10L	0.2
HNSC	chr22	36292103	In_Frame_Del	novel	D1409del	0.09
HNSC	chr22	36285671	In_Frame_Del	novel	N1744_K1753del	0.08
HNSC	chr22	36320273	Frame_Shift_Ins	novel	*Q320Lfs48**	0.09
HNSC	chr22	36312175	Silent	novel	F534F	0.23
HNSC	chr22	36285330	Splice_Site	novel	X1759_splice	0.36
HNSC	chr22	36294189	Missense_Mutation	novel	R1247P	0.35
HNSC	chr22	36314306	Missense_Mutation	NA	E465Q	0.28
KICH	chr22	36301592	Missense_Mutation	novel	R858K	0.61
KIRC	chr22	36285198	Silent	rs374979658	K1802K	0.2
KIRC	chr22	36327458	Splice_Region	novel		0.37
KIRC	chr22	36296974	Silent	NA	E1047E	0.32
KIRP	chr22	36306518	Frame_Shift_Del	novel	*F643Lfs13**	0.42
KIRP	chr22	36320827	Missense_Mutation	NA	L280H	0.24
KIRP	chr22	36300210	Missense_Mutation	NA	E965Q	0.44
LGG	chr22	36288306	Silent	rs143947828	I1626I	0.42
LGG	chr22	36301549	Silent	novel	E872E	0.41
LGG	chr22	36320317	Silent	novel	N305N	0.07
LGG	chr22	36285918	Silent	novel	A1699A	0.34
LIHC	chr22	36288407	Nonsense_Mutation	NA	E1593*	0.4
LIHC	chr22	36306606	Splice_Region	novel	V615V	0.39
LIHC	chr22	36293383	Silent	NA	E1347E	0.22
LIHC	chr22	36304138	Silent	NA	L749L	0.16
LIHC	chr22	36325096	Intron	novel		0.48
LIHC	chr22	36288249	Splice_Region	rs763903591		0.35
LUAD	chr22	36312129	Nonsense_Mutation	NA	Q550*	0.11
LUAD	chr22	36341415	Missense_Mutation	NA	H149D	0.07
LUAD	chr22	36322436	Missense_Mutation	NA	S233F	0.12
LUAD	chr22	36314180	Missense_Mutation	NA	D507H	0.17
LUAD	chr22	36284483	Missense_Mutation	NA	R1838C	0.24
LUAD	chr22	36301050	Missense_Mutation	novel	A880E	0.15
LUAD	chr22	36327484	Silent	NA	R165R	0.22
LUAD	chr22	36312192	Missense_Mutation	NA	D529Y	0.11
LUAD	chr22	36288362	Missense_Mutation	novel	A1608S	0.21
LUAD	chr22	36294126	Missense_Mutation	novel	R1268L	0.09
LUAD	chr22	36282527	3'UTR	novel		0.06
LUAD	chr22	36341412	Missense_Mutation	novel	I150F	0.28
LUAD	chr22	36304038	Missense_Mutation	rs761808742	I783V	0.26
LUAD	chr22	36285705	Missense_Mutation	novel	G1743C	0.23
LUAD	chr22	36295651	Silent	NA	I1113I	0.2
LUAD	chr22	36293406	Missense_Mutation	NA	S1340T	0.31
LUAD	chr22	36288318	Silent	novel	L1622L	0.09
LUAD	chr22	36294966	Missense_Mutation	novel	E1199V	0.34
LUAD	chr22	36312117	Missense_Mutation	NA	P554T	0.05
LUAD	chr22	36320821	Missense_Mutation	novel	S282C	0.45
LUAD	chr22	36341416	Frame_Shift_Ins	novel	*H149Sfs27**	0.11
LUAD	chr22	36320847	Frame_Shift_Del	novel	*Q267Sfs15**	0.19
LUSC	chr22	36289190	Silent	rs569164493	A1484A	0.64
LUSC	chr22	36295649	Missense_Mutation	NA	S1114C	0.17
LUSC	chr22	36309356	Missense_Mutation	novel	D590G	0.36
LUSC	chr22	36295710	Missense_Mutation	novel	E1094Q	0.15
LUSC	chr22	36320341	Nonsense_Mutation	novel	Y297*	0.18
LUSC	chr22	36285309	Silent	rs756456712	D1765D	0.15
LUSC	chr22	36318305	Missense_Mutation	NA	L377F	0.26
LUSC	chr22	36309346	Missense_Mutation	NA	N593K	0.22
LUSC	chr22	36341425	Missense_Mutation	NA	E145D	0.28
LUSC	chr22	36294965	Missense_Mutation	NA	E1199D	0.66
LUSC	chr22	36296905	Missense_Mutation	NA	Q1070H	0.21
LUSC	chr22	36304092	Frame_Shift_Ins	novel	*A765Lfs138**	0.07
LUSC	chr22	36327460	Splice_Site	NA	X173_splice	0.21
LUSC	chr22	36284111	Missense_Mutation	novel	S1916F	0.62
LUSC	chr22	36306535	Missense_Mutation	NA	R639Q	0.36
LUSC	chr22	36292080	Missense_Mutation	NA	R1417Q	0.06
LUSC	chr22	36314237	Missense_Mutation	NA	E488Q	0.04
LUSC	chr22	36306468	Silent	novel	L661L	0.16
LUSC	chr22	36318264	Silent	novel	L390L	0.18
LUSC	chr22	36327479	Missense_Mutation	novel	D167V	0.35
LUSC	chr22	36299016	Silent	novel	I1001I	0.31
LUSC	chr22	36284511	Frame_Shift_Ins	novel	*E1829Pfs18**	0.13
LUSC	chr22	36285782	Splice_Site	novel	X1717_splice	0.08
LUSC	chr22	36322523	Splice_Site	novel	X205_splice	0.5
LUSC	chr22	36284511	Frame_Shift_Ins	novel	*K1828Nfs27**	0.34
LUSC	chr22	36285736	In_Frame_Ins	novel	A1732_Q1733insCLLQKIHS	0.31
LUSC	chr22	36312195	Silent	novel	L528L	0.29
LUSC	chr22	36289202	Silent	novel	S1480S	0.09
LUSC	chr22	36314292	Missense_Mutation	NA	I469M	0.32
LUSC	chr22	36306003	Missense_Mutation	novel	G696S	0.06
LUSC	chr22	36319592	Silent	rs727504861	I352I	0.4
LUSC	chr22	36300889	Silent	novel	L934L	0.23
LUSC	chr22	36304099	Missense_Mutation	novel	F762L	0.17
LUSC	chr22	36285782	Splice_Site	novel	X1717_splice	0.05
LUSC	chr22	36288399	In_Frame_Del	novel	M1594_E1595del	0.04
LUSC	chr22	36294171	Missense_Mutation	NA	Q1253P	0.07
LUSC	chr22	36284511	Frame_Shift_Ins	novel	*K1828Nfs23**	0.08
LUSC	chr22	36288370	Missense_Mutation	NA	R1605L	0.18
LUSC	chr22	36292109	Silent	novel	A1407A	0.15
LUSC	chr22	36288939	Frame_Shift_Ins	novel	*V1520Cfs137**	0.09
LUSC	chr22	36305057	Silent	rs370860479	D735D	0.34
LUSC	chr22	36321820	Missense_Mutation	novel	G236A	0.31
LUSC	chr22	36304039	Silent	novel	V782V	0.2
MESO	chr22	36316529	Missense_Mutation	novel	F456L	0.47
OV	chr22	36285287	Frame_Shift_Ins	novel	*A1773Sfs19**	0.04
OV	chr22	36320812	Missense_Mutation	novel	G285E	0.06
OV	chr22	36316639	Missense_Mutation	NA	A420S	0.55
OV	chr22	36288745	Silent	novel	K1584K	0.16
OV	chr22	36288747	Missense_Mutation	novel	K1584E	0.13
OV	chr22	36298993	Missense_Mutation	NA	T1009I	1
OV	chr22	36327471	Missense_Mutation	novel	I170F	1
OV	chr22	36300866	In_Frame_Del	novel	E937_M941del	0.41
OV	chr22	36292165	Missense_Mutation	NA	K1389Q	0.17
OV	chr22	36305050	Nonsense_Mutation	NA	Q738*	0.15
OV	chr22	36304078	Silent	novel	A769A	0.11
OV	chr22	36300165	Nonsense_Mutation	NA	Q980*	0.64
OV	chr22	36289234	Missense_Mutation	novel	E1470Q	0.38
PAAD	chr22	36309386	Missense_Mutation	novel	K580T	0.08
PAAD	chr22	36289134	Missense_Mutation	rs549408311	R1503H	0.06
PCPG	chr22	36294109	Missense_Mutation	rs776320326	K1274E	0.39
PRAD	chr22	36312134	Missense_Mutation	novel	Q548L	0.1
PRAD	chr22	36285926	Missense_Mutation	rs372871106	R1697C	0.11
PRAD	chr22	36319564	Nonsense_Mutation	novel	Q362*	0.31
PRAD	chr22	36300241	Silent	NA	E954E	0.11
PRAD	chr22	36286804	Missense_Mutation	rs371410108	A1659T	0.35
PRAD	chr22	36288410	Missense_Mutation	novel	R1592W	0.44
PRAD	chr22	36304149	Missense_Mutation	novel	A746S	0.41
PRAD	chr22	36314217	Silent	rs771459391	R494R	0.47
READ	chr22	36288281	Missense_Mutation	NA	E1635K	0.42
READ	chr22	36349065	Silent	novel	L58L	0.12
READ	chr22	36293789	Silent	NA	S1304S	0.19
READ	chr22	36288332	Missense_Mutation	rs771657500	D1618Y	0.55
READ	chr22	36293464	Missense_Mutation	NA	E1320D	0.38
SARC	chr22	36291996	Missense_Mutation	novel	K1445T	0.32
SARC	chr22	36284128	Missense_Mutation	novel	M1910I	0.14
SARC	chr22	36282740	Silent	rs757593797	K1937K	0.73
SARC	chr22	36341392	Silent	rs727503293	T156T	0.36
SARC	chr22	36349187	Missense_Mutation	novel	I17T	0.08
SARC	chr22	36285216	Missense_Mutation	novel	E1796D	0.26
SARC	chr22	36293789	Silent	NA	S1304S	0.25
SKCM	chr22	36284244	Silent	NA	L1872L	0.33
SKCM	chr22	36302571	Silent	rs769382495	T832T	0.2
SKCM	chr22	36304102	Silent	NA	V761V	0.36
SKCM	chr22	36300946	Nonsense_Mutation	novel	E915*	0.05
SKCM	chr22	36318305	Missense_Mutation	NA	L377F	0.3
SKCM	chr22	36302640	Missense_Mutation	NA	M809I	0.47
SKCM	chr22	36282614	3'UTR	novel		0.39
SKCM	chr22	36305968	Silent	novel	G707G	0.21
SKCM	chr22	36293842	Missense_Mutation	rs781586533	G1287R	0.24
SKCM	chr22	36282526	3'UTR	novel		0.3
SKCM	chr22	36306423	Silent	rs768833414	H676H	0.14
SKCM	chr22	36293404	Silent	NA	S1340S	0.22
SKCM	chr22	36320225	Missense_Mutation	novel	Q336R	0.4
SKCM	chr22	36285195	Silent	NA	S1803S	0.37
SKCM	chr22	36295001	Silent	NA	I1187I	0.33
SKCM	chr22	36319622	Silent	novel	V342V	0.26
SKCM	chr22	36300976	Missense_Mutation	rs377115843	R905C	0.22
SKCM	chr22	36295647	Missense_Mutation	NA	E1115K	0.44
SKCM	chr22	36306037	Silent	rs768538586	D684D	0.4
SKCM	chr22	36284111	Missense_Mutation	novel	S1916F	0.14
SKCM	chr22	36304027	Silent	NA	F786F	0.42
SKCM	chr22	36318260	Missense_Mutation	NA	P392S	0.29
SKCM	chr22	36294262	Nonsense_Mutation	NA	E1223*	0.46
SKCM	chr22	36296902	Silent	rs552133535	I1071I	0.15
SKCM	chr22	36312117	Missense_Mutation	NA	P554S	0.4
SKCM	chr22	36304036	Silent	rs774263441	I783I	0.16
SKCM	chr22	36282520	3'UTR	novel		0.39
SKCM	chr22	36282603	3'UTR	novel		0.13
SKCM	chr22	36320320	Silent	novel	S304S	0.25
SKCM	chr22	36289106	Silent	rs546744981	S1512S	0.31
SKCM	chr22	36289107	Missense_Mutation	NA	S1512F	0.31
SKCM	chr22	36316618	Missense_Mutation	novel	R427C	0.17
SKCM	chr22	36288909	Silent	novel	L1530L	0.35
SKCM	chr22	36288910	Silent	rs748755706	A1529A	0.35
SKCM	chr22	36293404	Silent	NA	S1340S	0.33
SKCM	chr22	36305965	Silent	novel	F708F	0.42
SKCM	chr22	36326634	Silent	NA	E182E	0.86
SKCM	chr22	36282526	3'UTR	novel		0.32
SKCM	chr22	36296914	Silent	rs144389749	L1067L	0.38
SKCM	chr22	36292208	Silent	NA	E1374E	0.34
SKCM	chr22	36318286	Missense_Mutation	NA	T383I	0.6
SKCM	chr22	36314193	Silent	rs779557497	I502I	0.12
SKCM	chr22	36319592	Silent	rs727504861	I352I	0.18
SKCM	chr22	36318267	Silent	rs114048959	I389I	0.31
STAD	chr22	36288827	Missense_Mutation	rs373393111	R1557Q	0.24
STAD	chr22	36300915	Missense_Mutation	NA	E925V	0.15
STAD	chr22	36294247	Frame_Shift_Del	NA	*E1228Sfs6**	0.35
STAD	chr22	36293415	Missense_Mutation	NA	E1337K	0.18
STAD	chr22	36299025	Silent	NA	E998E	0.05
STAD	chr22	36318256	Missense_Mutation	rs202023656	R393H	0.26
STAD	chr22	36318257	Missense_Mutation	novel	R393C	0.27
STAD	chr22	36285737	Missense_Mutation	NA	A1732V	0.29
STAD	chr22	36314237	Missense_Mutation	NA	E488Q	0.22
STAD	chr22	36284506	Missense_Mutation	NA	R1830H	0.1
STAD	chr22	36288881	Missense_Mutation	rs772323929	T1539M	0.05
STAD	chr22	36293400	Missense_Mutation	rs147901502	R1342W	0.32
STAD	chr22	36288846	Missense_Mutation	novel	T1551A	0.17
STAD	chr22	36294126	Missense_Mutation	rs768022369	R1268H	0.48
STAD	chr22	36288384	Silent	rs201223994	D1600D	0.28
STAD	chr22	36327485	Missense_Mutation	rs576081279	R165Q	0.22
STAD	chr22	36296932	Silent	rs778202463	S1061S	0.35
STAD	chr22	36294130	Missense_Mutation	rs756528783	V1267M	0.28
STAD	chr22	36318223	Missense_Mutation	NA	A404V	0.27
STAD	chr22	36312211	Silent	rs145517108	P522P	0.27
STAD	chr22	36348957	Missense_Mutation	NA	E94K	0.33
STAD	chr22	36302626	Missense_Mutation	rs760924443	R814Q	0.2
STAD	chr22	36305962	Frame_Shift_Del	novel	*N710Tfs15**	0.25
STAD	chr22	36293346	Missense_Mutation	rs569649580	A1360T	0.15
STAD	chr22	36320299	Frame_Shift_Del	novel	*Q313Sfs14**	0.45
STAD	chr22	36288902	Missense_Mutation	rs11549910	Q1532R	0.11
STAD	chr22	36296866	Silent	NA	E1083E	0.09
STAD	chr22	36284187	Missense_Mutation	rs748946434	A1891T	0.36
STAD	chr22	36304052	Missense_Mutation	NA	K778T	0.11
STAD	chr22	36326632	Missense_Mutation	novel	N183S	0.73
STAD	chr22	36286825	Missense_Mutation	NA	R1652C	0.22
STAD	chr22	36349212	Missense_Mutation	NA	Y9H	0.21
STAD	chr22	36341416	Frame_Shift_Ins	novel	*H149Sfs27**	0.31
STAD	chr22	36284453	Silent	NA	L1848L	0.09
STAD	chr22	36288780	Missense_Mutation	NA	L1573M	0.32
STAD	chr22	36294152	Silent	NA	V1259V	0.22
STAD	chr22	36282744	Missense_Mutation	rs781388651	R1936Q	0.25
STAD	chr22	36300205	In_Frame_Del	novel	K966del	0.05
STAD	chr22	36288744	Missense_Mutation	rs149169068	K1585Q	0.67
STAD	chr22	36284437	Nonsense_Mutation	novel	*D1853Gfs2**	0.37
STAD	chr22	36285656	Splice_Site	NA	X1758_splice	0.1
STAD	chr22	36312200	Missense_Mutation	NA	A526V	0.09
STAD	chr22	36312094	Missense_Mutation	NA	Q561H	0.14
STAD	chr22	36288367	Missense_Mutation	rs145319741	S1606L	0.3
STAD	chr22	36296988	Nonsense_Mutation	NA	R1043*	0.42
STAD	chr22	36322519	Splice_Region	rs139466141	G205G	0.33
STAD	chr22	36318233	Missense_Mutation	rs369581570	V401I	0.15
STAD	chr22	36302619	Silent	rs113285582	C816C	0.22
TGCT	chr22	36320879	Missense_Mutation	NA	R263C	0.17
THYM	chr22	36282614	3'UTR	novel		0.11
THYM	chr22	36349107	Missense_Mutation	novel	A44T	0.09
UCEC	chr22	36292023	Missense_Mutation	NA	A1436V	0.26
UCEC	chr22	36288933	Missense_Mutation	NA	E1522K	0.42
UCEC	chr22	36309378	Missense_Mutation	NA	E583K	0.37
UCEC	chr22	36322433	Missense_Mutation	NA	R234H	0.45
UCEC	chr22	36288790	Silent	rs576697687	F1569F	0.12
UCEC	chr22	36295570	Silent	novel	E1140E	0.21
UCEC	chr22	36300190	Silent	rs200763055	A971A	0.19
UCEC	chr22	36304044	Missense_Mutation	rs766088687	D781N	0.18
UCEC	chr22	36321775	Missense_Mutation	novel	G251E	0.39
UCEC	chr22	36288790	Silent	rs576697687	F1569F	0.08
UCEC	chr22	36292126	Missense_Mutation	NA	E1402K	0.18
UCEC	chr22	36320795	Splice_Region	novel		0.32
UCEC	chr22	36305047	Missense_Mutation	novel	A739T	0.14
UCEC	chr22	36300196	Silent	rs767461889	T969T	0.33
UCEC	chr22	36306002	Missense_Mutation	novel	G696D	0.14
UCEC	chr22	36304088	Missense_Mutation	novel	G766D	0.18
UCEC	chr22	36281581	3'UTR	novel		0.65
UCEC	chr22	36288843	Missense_Mutation	novel	E1552K	0.38
UCEC	chr22	36298964	Missense_Mutation	rs566644790	A1019T	0.36
UCEC	chr22	36326595	Silent	rs374395918	A195A	0.46
UCEC	chr22	36284483	Missense_Mutation	NA	R1838C	0.53
UCEC	chr22	36296901	Missense_Mutation	rs532156048	A1072T	0.43
UCEC	chr22	36304018	Silent	novel	C789C	0.53
UCEC	chr22	36312169	Missense_Mutation	novel	K536N	0.35
UCEC	chr22	36314158	Missense_Mutation	novel	L514P	0.42
UCEC	chr22	36349218	Missense_Mutation	NA	D7N	0.2
UCEC	chr22	36281935	3'UTR	novel		0.64
UCEC	chr22	36326605	Missense_Mutation	novel	A192V	0.48
UCEC	chr22	36282630	3'UTR	novel		0.23
UCEC	chr22	36285156	Silent	NA	I1816I	0.22
UCEC	chr22	36292202	Missense_Mutation	NA	S1376R	0.24
UCEC	chr22	36300232	Silent	rs374840260	S957S	0.25
UCEC	chr22	36288300	Silent	novel	S1628S	0.21
UCEC	chr22	36288933	Missense_Mutation	NA	E1522K	0.14
UCEC	chr22	36296994	Missense_Mutation	novel	K1041Q	0.32
UCEC	chr22	36304059	Missense_Mutation	NA	D776Y	0.8
UCEC	chr22	36285738	Missense_Mutation	novel	A1732T	0.11
UCEC	chr22	36299037	Missense_Mutation	novel	K994N	0.41
UCEC	chr22	36301046	Missense_Mutation	novel	E881D	0.11
UCEC	chr22	36314277	Silent	novel	E474E	0.48
UCEC	chr22	36306512	Missense_Mutation	NA	G647W	0.25
UCEC	chr22	36281606	3'UTR	novel		0.5
UCEC	chr22	36288877	Silent	novel	Q1540Q	0.25
UCEC	chr22	36294091	Splice_Site	novel	X1279_splice	0.27
UCEC	chr22	36312212	Missense_Mutation	NA	P522L	0.3
UCEC	chr22	36318322	Missense_Mutation	novel	A371V	0.16
UCEC	chr22	36322493	Missense_Mutation	novel	A214V	0.37
UCEC	chr22	36295586	Missense_Mutation	novel	R1135Q	0.2
UCEC	chr22	36286738	Missense_Mutation	novel	E1681K	0.45
UCEC	chr22	36288881	Missense_Mutation	rs772323929	T1539M	0.44
UCEC	chr22	36293406	Missense_Mutation	novel	S1340P	0.25
UCEC	chr22	36306034	Silent	rs756137861	P685P	0.32
UCEC	chr22	36318242	Missense_Mutation	NA	R398W	0.76
UCEC	chr22	36349027	Silent	novel	D70D	0.39
UCEC	chr22	36284124	Missense_Mutation	NA	R1912C	0.46
UCEC	chr22	36281453	3'UTR	novel		0.41
UCEC	chr22	36284123	Missense_Mutation	NA	R1912H	0.4
UCEC	chr22	36285940	Missense_Mutation	rs558195536	A1692V	0.35
UCEC	chr22	36282726	Missense_Mutation	novel	G1942D	0.53
UCEC	chr22	36282010	3'UTR	novel		0.53
UCEC	chr22	36293792	Missense_Mutation	novel	F1303L	0.48
UCEC	chr22	36322459	Silent	rs776603431	K225K	0.43
UCEC	chr22	36349030	Missense_Mutation	novel	K69N	0.5
UCEC	chr22	36285909	Silent	rs747668125	E1702E	0.34
UCEC	chr22	36289195	Missense_Mutation	rs368105628	R1483W	0.3
UCEC	chr22	36306027	Missense_Mutation	rs757396174	V688M	0.53
UCEC	chr22	36309299	Missense_Mutation	rs750091087	S609L	0.4
UCEC	chr22	36319545	Missense_Mutation	NA	N368S	0.34
UCEC	chr22	36321809	Missense_Mutation	rs766168499	R240C	0.36
UCEC	chr22	36306601	Missense_Mutation	rs151240427	R617H	0.47
UCEC	chr22	36312162	Missense_Mutation	NA	D539N	0.07
UCEC	chr22	36294127	Missense_Mutation	rs750701311	R1268C	0.33
UCEC	chr22	36298982	Missense_Mutation	novel	E1013K	0.33
UCEC	chr22	36318280	Missense_Mutation	novel	F385S	0.27
UCEC	chr22	36285891	Silent	rs369135992	D1708D	0.45
UCEC	chr22	36306459	Silent	rs202125487	T664T	0.26
UCEC	chr22	36320894	Missense_Mutation	novel	L258I	0.23
UCEC	chr22	36282525	3'UTR	novel		0.48
UCEC	chr22	36286739	Silent	novel	A1680A	0.4
UCEC	chr22	36296964	Missense_Mutation	novel	R1051W	0.37
UCEC	chr22	36304147	Silent	novel	A746A	0.46
UCEC	chr22	36301594	Silent	rs771942552	V857V	0.28
UCEC	chr22	36318284	Missense_Mutation	rs767088377	D384N	0.62
UCEC	chr22	36282311	3'UTR	novel		0.29
UCEC	chr22	36293347	Silent	rs199693307	I1359I	0.4
UCEC	chr22	36294113	Silent	rs752273735	A1272A	0.5
UCEC	chr22	36306459	Silent	rs202125487	T664T	0.3
UCEC	chr22	36306567	Silent	rs142260563	S628S	0.39
UCEC	chr22	36320364	Splice_Site	NA	X290_splice	0.43
UCEC	chr22	36320855	Nonsense_Mutation	NA	E271*	0.17
UCEC	chr22	36302633	Missense_Mutation	novel	L812I	0.17
UCEC	chr22	36327464	Missense_Mutation	novel	C172Y	0.16
UCEC	chr22	36294247	Frame_Shift_Del	NA	*E1228Sfs6**	0.22
UCEC	chr22	36288738	Silent	novel	L1587L	0.31
UCEC	chr22	36309286	Missense_Mutation	novel	K613N	0.18
UCEC	chr22	36349064	Missense_Mutation	novel	L58P	0.11
UCEC	chr22	36294976	Nonsense_Mutation	NA	Q1196*	0.19
UCEC	chr22	36298928	Missense_Mutation	NA	D1031Y	0.47
UCEC	chr22	36284142	Missense_Mutation	NA	T1906P	0.42
UCEC	chr22	36289107	Missense_Mutation	NA	S1512F	0.12
UCEC	chr22	36282656	3'UTR	novel		0.27
UCEC	chr22	36298978	Missense_Mutation	novel	K1014T	0.34
UCEC	chr22	36316602	Missense_Mutation	rs769199813	R432H	0.16
UCEC	chr22	36321767	Missense_Mutation	novel	I254V	0.19
UCEC	chr22	36299037	Missense_Mutation	novel	K994N	0.07
UCEC	chr22	36348925	Silent	novel	R104R	0.38
UCEC	chr22	36282074	3'UTR	novel		0.24
UCEC	chr22	36319561	Missense_Mutation	novel	A363T	0.39
UCS	chr22	36289134	Missense_Mutation	rs549408311	R1503H	0.32
UCS	chr22	36301615	Missense_Mutation	novel	K850N	0.21

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
PCPG	DEL	0.3148	0.044123
THCA	DEL	0.1583	0.046486
THYM	DEL	0.0732	0.063154

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0097	Kaplan-Meier Survival Analysis
MESO	0.00021	Kaplan-Meier Survival Analysis
ACC	0.0077	Kaplan-Meier Survival Analysis
ESCA	0.003	Kaplan-Meier Survival Analysis
KIRP	0.038	Kaplan-Meier Survival Analysis
PAAD	0.038	Kaplan-Meier Survival Analysis
PCPG	0.048	Kaplan-Meier Survival Analysis
READ	0.043	Kaplan-Meier Survival Analysis
LAML	0.0026	Kaplan-Meier Survival Analysis
KICH	0.037	Kaplan-Meier Survival Analysis
GBM	0.041	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000100345 (Gene tree)
Gene ID: 4627
Gene Symbol: MYH9
Alias: NMMHCA|NMHC-II-A|MHA|FTNS|EPSTS|DFNA17
Full Name: myosin heavy chain 9
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 106,791 bases
Position: chr22:36,281,277-36,388,067
Accession: 7579
RBP type: non-canonical RBP
Summary: This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000472210	MYH9-206	387	-	-	- (aa)	-	-
ENST00000495928	MYH9-211	329	-	-	- (aa)	-	-
ENST00000477189	MYH9-209	572	-	-	- (aa)	-	-
ENST00000475726	MYH9-208	768	-	-	- (aa)	-	-
ENST00000216181	MYH9-201	7554	XM_011530197	ENSP00000216181	1960 (aa)	XP_011528499	P35579
ENST00000486218	MYH9-210	788	-	-	- (aa)	-	-
ENST00000473022	MYH9-207	400	-	-	- (aa)	-	-
ENST00000456729	MYH9-203	449	-	ENSP00000414852	103 (aa)	-	B1AH99
ENST00000463027	MYH9-205	562	-	-	- (aa)	-	-
ENST00000459960	MYH9-204	687	-	-	- (aa)	-	-
ENST00000401701	MYH9-202	789	-	ENSP00000384631	218 (aa)	-	Q5BKV1

Gene Model

Click here to download ENSG00000100345's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04530	Tight junction	KEGG
hsa04810	Regulation of actin cytoskeleton	KEGG
hsa05132	Salmonella infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000100345	Platelet Function Tests	5.6800000E-007	-
ENSG00000100345	Platelet Function Tests	1.4800000E-007	-
ENSG00000100345	Platelet Function Tests	4.2654770E-013	-
ENSG00000100345	Platelet Function Tests	9.0094927E-006	-
ENSG00000100345	alpha-Linolenic Acid	2.0180000E-005	21829377
ENSG00000100345	alpha-Linolenic Acid	8.4620000E-006	21829377
ENSG00000100345	Diabetic Nephropathies	8E-8	26305897
ENSG00000100345	Cleft Lip	6E-6	28232668
ENSG00000100345	Cleft Palate	6E-6	28232668
ENSG00000100345	Diabetic Nephropathies	8E-8	26305897
ENSG00000100345	Optic Disk	9E-6	20395239

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000100345	rs136211	22	36362502	G	Mean corpuscular hemoglobin	27863252	[0.022-0.037] unit decrease	0.02953162	EFO_0004527
ENSG00000100345	rs136211	22	36362502	G	Mean corpuscular volume	27863252	[0.021-0.037] unit decrease	0.02906488	EFO_0004526
ENSG00000100345	rs5750250	22	36312438	G	Diabetic kidney disease	26305897	[1.16-1.38]	1.27	EFO_0000401
ENSG00000100345	rs5750250	22	36312438	G	Diabetic kidney disease	26305897	[1.16-1.38]	1.27	EFO_0000401
ENSG00000100345	rs735854	22	36283012	C	Optic nerve measurement (rim area)	20395239	[0.072-0.240] unit decrease	0.156	EFO_0004832
ENSG00000100345	rs5756130	22	36288285	A	Nonsyndromic cleft lip with cleft palate	28232668		1.21	HP_0000175\|EFO_0003959
ENSG00000100345	rs13053731	22	36286661	?	Language performance in older adults (adjusted for episodic memory)	28577822	[0.18-0.42] unit decrease	0.301	EFO_0007710\|EFO_0004874\|EFO_0007797
ENSG00000100345	rs2071732	22	36284668	C	Blood protein levels	30072576	[0.34-0.53] unit decrease	0.437	EFO_0007937
ENSG00000100345	rs62232665	22	36290480	G	Blood protein levels	30072576	[0.11-0.29] unit increase	0.202	EFO_0007937
ENSG00000100345	rs7078	22	36281868	?	Heel bone mineral density	30048462	[0.019-0.028] unit decrease	0.0232588	EFO_0009270
ENSG00000100345	rs776420285	22	36336957	G	Hip circumference	30108283	[4.62-10.59] cm increase	7.604	EFO_0005093
ENSG00000100345	rs2294358	22	36375211	G	Heel bone mineral density	30598549	[0.028-0.044] unit decrease	0.0363772	EFO_0009270
ENSG00000100345	rs136211	22	36362502	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000100345	rs7078	22	36281868	?	Heel bone mineral density	30595370			EFO_0009270
ENSG00000100345	rs9610482	22	36287509	?	Lung function (FEV1/FVC)	30595370			EFO_0004713

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000100345's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000100345	MYH9	100	98.058	ENSMUSG00000022443	Myh9	100	97.092	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000146	microfilament motor activity	12237319.15845534.	IDA	Function
GO:0000212	meiotic spindle organization	-	IEA	Process
GO:0001525	angiogenesis	16403913.	IDA	Process
GO:0001701	in utero embryonic development	-	IEA	Process
GO:0001725	stress fiber	7699007.14508515.14706930.15774463.16403913.	IDA	Component
GO:0001726	ruffle	16403913.	IDA	Component
GO:0001768	establishment of T cell polarity	-	IEA	Process
GO:0001772	immunological synapse	15064761.	IDA	Component
GO:0001778	plasma membrane repair	27325790.	IDA	Process
GO:0001931	uropod	15064761.	IDA	Component
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003774	motor activity	12421915.	NAS	Function
GO:0003779	actin binding	15065866.	IDA	Function
GO:0005178	integrin binding	10822899.	IDA	Function
GO:0005515	protein binding	10822899.12202484.12421915.12577067.14508515.14640694.15479433.16186248.16403913.17925381.18504258.20421509.20603131.20936779.22229724.22483112.23100250.24189400.27325790.28228547.	IPI	Function
GO:0005516	calmodulin binding	-	IEA	Function
GO:0005524	ATP binding	15065866.15845534.	IDA	Function
GO:0005634	nucleus	14508515.	IDA	Component
GO:0005737	cytoplasm	7699007.	IDA	Component
GO:0005819	spindle	-	IEA	Component
GO:0005826	actomyosin contractile ring	11029059.	IDA	Component
GO:0005829	cytosol	14508515.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	16186248.16403913.	IDA	Component
GO:0005886	plasma membrane	15064761.	IDA	Component
GO:0005903	brush border	-	IEA	Component
GO:0005913	cell-cell adherens junction	-	IEA	Component
GO:0005925	focal adhesion	-	ISS	Component
GO:0006509	membrane protein ectodomain proteolysis	16186248.	IDA	Process
GO:0006911	phagocytosis, engulfment	-	ISS	Process
GO:0007229	integrin-mediated signaling pathway	10822899.	NAS	Process
GO:0007520	myoblast fusion	-	IEA	Process
GO:0008180	COP9 signalosome	18850735.	IDA	Component
GO:0008360	regulation of cell shape	11029059.	IMP	Process
GO:0015031	protein transport	16403913.	IMP	Process
GO:0015629	actin cytoskeleton	15869600.	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016460	myosin II complex	24072716.	IDA	Component
GO:0016887	ATPase activity	12237319.24072716.	IDA	Function
GO:0019904	protein domain specific binding	23325791.	IPI	Function
GO:0030048	actin filament-based movement	12237319.15845534.	IDA	Process
GO:0030220	platelet formation	12237319.	IMP	Process
GO:0030224	monocyte differentiation	1912569.	IEP	Process
GO:0030898	actin-dependent ATPase activity	15065866.15845534.	IDA	Function
GO:0030898	actin-dependent ATPase activity	24072716.	IDA	Function
GO:0031032	actomyosin structure organization	24072716.	IDA	Process
GO:0031252	cell leading edge	12421915.	IDA	Component
GO:0031532	actin cytoskeleton reorganization	15869600.	IMP	Process
GO:0031594	neuromuscular junction	-	IEA	Component
GO:0032154	cleavage furrow	7699007.14508515.	IDA	Component
GO:0032506	cytokinetic process	15774463.	IMP	Process
GO:0032796	uropod organization	-	IEA	Process
GO:0032991	protein-containing complex	12421915.	IDA	Component
GO:0042641	actomyosin	24072716.	IDA	Component
GO:0042803	protein homodimerization activity	12237319.	IDA	Function
GO:0043495	protein membrane anchor	16403913.	IMP	Function
GO:0043531	ADP binding	15065866.	IDA	Function
GO:0043534	blood vessel endothelial cell migration	16403913.	IMP	Process
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0050900	leukocyte migration	12421915.	NAS	Process
GO:0051015	actin filament binding	12237319.14508515.15845534.	IDA	Function
GO:0051015	actin filament binding	24072716.	IDA	Function
GO:0051015	actin filament binding	16403913.	NAS	Function
GO:0051295	establishment of meiotic spindle localization	-	IEA	Process
GO:0070062	extracellular exosome	19056867.19199708.20458337.21362503.23533145.	HDA	Component
GO:0070527	platelet aggregation	23382103.	HMP	Process
GO:0097513	myosin II filament	24072716.	IDA	Component
GO:1903919	negative regulation of actin filament severing	23325791.	IMP	Process
GO:1903919	negative regulation of actin filament severing	-	ISS	Process
GO:1903923	positive regulation of protein processing in phagocytic vesicle	-	ISS	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.