EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26626481	NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.	Mol Cell	2015 Dec 17	Shen C	doi: 10.1016/j.molcel.2015.10.033
25499215	Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer.	Neoplasia	2014 Dec	Damaschke NA	doi: 10.1016/j.neo.2014.10.003.
23835524	CHD8 is an independent prognostic indicator that regulates Wnt/β-catenin signaling and the cell cycle in gastric cancer.	Oncol Rep	2013 Sep	Sawada G	doi: 10.3892/or.2013.2597
20215423	Improved survival in BRCA2 carriers with ovarian cancer.	Fam Cancer	2007	Pal T	-

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr14	21394997	Frame_Shift_Ins	novel	*A1769Rfs19**	0.67
BLCA	chr14	21393735	Silent	novel	E2020E	0.22
BLCA	chr14	21400943	Missense_Mutation	novel	R1434S	0.33
BLCA	chr14	21415897	Nonsense_Mutation	novel	S576*	0.4
BLCA	chr14	21405345	Missense_Mutation	novel	Q1057H	0.18
BLCA	chr14	21402023	Silent	rs781129091	Q1332Q	0.06
BLCA	chr14	21402413	Missense_Mutation	NA	D1269H	0.05
BLCA	chr14	21430975	Silent	novel	V223V	0.27
BLCA	chr14	21395301	Missense_Mutation	NA	E1727K	0.2
BLCA	chr14	21429141	Silent	NA	Q346Q	0.09
BLCA	chr14	21431184	Nonsense_Mutation	novel	Q154*	0.61
BLCA	chr14	21414943	Silent	novel	K673K	0.56
BLCA	chr14	21408526	Missense_Mutation	novel	G839V	0.33
BLCA	chr14	21394048	Missense_Mutation	novel	P1916H	0.43
BLCA	chr14	21400286	Missense_Mutation	rs192277407	R1531H	0.33
BLCA	chr14	21426186	Nonsense_Mutation	NA	S553*	0.41
BLCA	chr14	21393232	Silent	novel	L2114L	0.24
BLCA	chr14	21400557	Missense_Mutation	novel	E1476K	0.58
BLCA	chr14	21400939	Missense_Mutation	novel	D1436N	0.48
BLCA	chr14	21405242	Missense_Mutation	NA	R1092C	0.13
BLCA	chr14	21408436	Missense_Mutation	NA	S869F	0.21
BLCA	chr14	21405744	Missense_Mutation	novel	G1010R	0.05
BLCA	chr14	21402037	Missense_Mutation	NA	E1328K	0.12
BLCA	chr14	21393220	Silent	novel	E2118E	0.48
BLCA	chr14	21394007	Missense_Mutation	NA	D1930N	0.33
BRCA	chr14	21403461	Silent	NA	I1170I	0.25
BRCA	chr14	21393816	Silent	novel	T1993T	0.07
BRCA	chr14	21401975	Frame_Shift_Del	NA	*G1349Vfs35**	0.35
BRCA	chr14	21391016	Frame_Shift_Ins	NA	*N2371Kfs2**	0.28
BRCA	chr14	21401041	Nonsense_Mutation	NA	R1402*	0.23
BRCA	chr14	21393173	Missense_Mutation	novel	D2134A	0.13
BRCA	chr14	21391532	Silent	novel	P2332P	0.05
BRCA	chr14	21394311	Silent	NA	R1855R	0.18
BRCA	chr14	21394312	Missense_Mutation	NA	R1855H	0.19
BRCA	chr14	21391015	Missense_Mutation	novel	N2372H	0.23
BRCA	chr14	21401000	Frame_Shift_Del	novel	*L1411Wfs59**	0.06
BRCA	chr14	21400604	Missense_Mutation	novel	R1460Q	0.15
BRCA	chr14	21393205	Silent	NA	L2123L	0.36
BRCA	chr14	21431228	Missense_Mutation	novel	S139C	0.1
BRCA	chr14	21391550	Silent	NA	L2326L	0.17
BRCA	chr14	21400553	Missense_Mutation	rs752291265	R1477Q	0.21
BRCA	chr14	21400037	Silent	rs372730716	L1587L	0.24
BRCA	chr14	21405421	Missense_Mutation	NA	R1032T	0.59
BRCA	chr14	21385311	3'UTR	novel		0.16
BRCA	chr14	21395112	Silent	rs768006197	V1730V	0.13
BRCA	chr14	21394033	Missense_Mutation	NA	P1921H	0.25
BRCA	chr14	21390968	Silent	novel	A2387A	0.1
BRCA	chr14	21400903	Missense_Mutation	rs759526072	R1448W	0.1
BRCA	chr14	21414943	Missense_Mutation	NA	K673N	0.14
BRCA	chr14	21399623	Missense_Mutation	NA	L1634V	0.27
BRCA	chr14	21401470	Missense_Mutation	NA	D1369V	0.23
BRCA	chr14	21391015	Missense_Mutation	novel	N2372H	0.07
BRCA	chr14	21400469	Missense_Mutation	NA	W1505L	0.25
BRCA	chr14	21409897	Missense_Mutation	rs763874660	R773Q	0.06
BRCA	chr14	21428196	Missense_Mutation	novel	S425I	0.1
CESC	chr14	21405397	Frame_Shift_Del	NA	*N1040Tfs12**	0.33
CESC	chr14	21400545	Missense_Mutation	NA	E1480Q	0.07
CESC	chr14	21431475	Missense_Mutation	NA	D57N	0.28
CESC	chr14	21393628	Missense_Mutation	rs572070685	R2056Q	0.2
CESC	chr14	21429127	Frame_Shift_Ins	NA	*I351Nfs70**	0.42
CESC	chr14	21401030	Frame_Shift_Ins	novel	*R1406Afs4**	0.14
CESC	chr14	21406921	Missense_Mutation	novel	D948H	0.33
CESC	chr14	21393570	Missense_Mutation	NA	L2075F	0.19
CESC	chr14	21415891	Missense_Mutation	NA	R578H	0.35
CESC	chr14	21392548	Nonsense_Mutation	novel	R2244*	0.41
CESC	chr14	21395051	Missense_Mutation	novel	R1751C	0.14
CESC	chr14	21400566	Missense_Mutation	novel	R1473C	0.38
CESC	chr14	21403634	Missense_Mutation	rs749785996	R1113C	0.39
CESC	chr14	21408754	Silent	novel	R812R	0.43
CESC	chr14	21429238	Missense_Mutation	novel	I314T	0.39
CESC	chr14	21393117	Missense_Mutation	NA	E2153Q	0.71
CESC	chr14	21385248	3'UTR	novel		0.41
CESC	chr14	21400230	Missense_Mutation	NA	D1550H	0.26
CESC	chr14	21431051	Missense_Mutation	NA	G198E	0.28
CESC	chr14	21414324	Missense_Mutation	novel	Q707E	0.38
CHOL	chr14	21429280	Frame_Shift_Ins	novel	*Q300Pfs121**	0.34
COAD	chr14	21403648	Frame_Shift_Ins	NA	*I1108Nfs7**	0.24
COAD	chr14	21391016	Frame_Shift_Ins	NA	*N2371Kfs2**	0.25
COAD	chr14	21385566	3'UTR	novel		0.4
COAD	chr14	21405448	Missense_Mutation	NA	A1023V	0.26
COAD	chr14	21394187	Frame_Shift_Ins	novel	*D1870Rfs3**	0.3
COAD	chr14	21394082	Frame_Shift_Del	NA	*L1905Ffs30**	0.28
COAD	chr14	21399628	Missense_Mutation	novel	S1632L	0.23
COAD	chr14	21415891	Missense_Mutation	NA	R578H	0.33
COAD	chr14	21391017	Frame_Shift_Del	rs751094013	*N2371Ifs6**	0.32
COAD	chr14	21409975	Missense_Mutation	novel	Y747C	0.12
COAD	chr14	21393713	Missense_Mutation	novel	H2028Y	0.24
COAD	chr14	21393913	Missense_Mutation	novel	R1961H	0.48
COAD	chr14	21403595	Nonsense_Mutation	NA	Q1126*	0.42
COAD	chr14	21414958	Missense_Mutation	NA	F668L	0.29
COAD	chr14	21414974	Missense_Mutation	NA	T663I	0.27
COAD	chr14	21397926	Missense_Mutation	novel	A1650T	0.32
COAD	chr14	21394106	Missense_Mutation	novel	R1897W	0.41
COAD	chr14	21385863	Missense_Mutation	NA	P2499H	0.4
COAD	chr14	21429127	Frame_Shift_Ins	NA	*I351Nfs70**	0.25
COAD	chr14	21391016	Frame_Shift_Ins	NA	*N2371Kfs2**	0.24
COAD	chr14	21395035	Missense_Mutation	NA	Y1756S	0.44
COAD	chr14	21403582	Missense_Mutation	rs765025620	R1130H	0.24
COAD	chr14	21409952	Missense_Mutation	NA	P755S	0.25
COAD	chr14	21428174	Silent	rs747526024	S432S	0.26
COAD	chr14	21385471	3'UTR	novel		0.78
COAD	chr14	21393201	Missense_Mutation	rs377109513	M2125V	0.16
COAD	chr14	21403198	Missense_Mutation	NA	R1178H	0.14
COAD	chr14	21428046	Missense_Mutation	NA	R475H	0.17
COAD	chr14	21392619	Missense_Mutation	NA	S2220I	0.47
COAD	chr14	21394082	Frame_Shift_Del	NA	*L1905Ffs30**	0.3
COAD	chr14	21400509	Silent	NA	L1492L	0.23
COAD	chr14	21414365	Missense_Mutation	novel	R693M	0.08
COAD	chr14	21400054	Nonsense_Mutation	novel	R1582*	0.19
COAD	chr14	21415835	Nonsense_Mutation	novel	E597*	0.06
COAD	chr14	21393540	In_Frame_Ins	novel	S2094dup	0.21
COAD	chr14	21403521	Missense_Mutation	NA	H1150Q	0.57
COAD	chr14	21390981	Missense_Mutation	rs751755659	P2383L	0.37
COAD	chr14	21405209	Missense_Mutation	NA	G1103C	0.2
COAD	chr14	21392513	Silent	novel	I2255I	0.14
COAD	chr14	21395350	Splice_Region	novel	G1710G	0.11
COAD	chr14	21405372	Missense_Mutation	NA	I1048M	0.2
COAD	chr14	21406951	Missense_Mutation	rs763248373	R938C	0.13
COAD	chr14	21408410	Missense_Mutation	NA	F878I	0.16
COAD	chr14	21415794	Silent	novel	P610P	0.21
COAD	chr14	21426189	Missense_Mutation	NA	N552T	0.23
COAD	chr14	21393920	Missense_Mutation	NA	A1959T	0.42
COAD	chr14	21400554	Nonsense_Mutation	NA	R1477*	0.24
COAD	chr14	21400903	Missense_Mutation	rs759526072	R1448W	0.37
COAD	chr14	21406924	Missense_Mutation	NA	I947V	0.32
COAD	chr14	21392779	Missense_Mutation	rs770593901	V2167I	0.31
COAD	chr14	21393914	Missense_Mutation	novel	R1961C	0.43
COAD	chr14	21400267	Frame_Shift_Del	novel	V1538*	0.4
COAD	chr14	21427992	Missense_Mutation	rs755646683	R493Q	0.31
COAD	chr14	21400477	Silent	novel	G1502G	0.18
COAD	chr14	21385930	Missense_Mutation	novel	M2477L	0.09
DLBC	chr14	21415871	Frame_Shift_Ins	novel	*Y585Ifs12**	0.26
ESCA	chr14	21400179	In_Frame_Ins	novel	Y1566dup	0.23
ESCA	chr14	21399702	Missense_Mutation	novel	E1607D	0.28
ESCA	chr14	21400267	Frame_Shift_Del	novel	V1538*	0.42
ESCA	chr14	21429153	Silent	novel	L342L	0.36
ESCA	chr14	21385660	Missense_Mutation	novel	P2567A	0.42
ESCA	chr14	21430852	Silent	novel	A264A	0.09
ESCA	chr14	21393581	Missense_Mutation	novel	E2072Q	0.44
ESCA	chr14	21430891	Silent	novel	Q251Q	0.5
ESCA	chr14	21395879	Nonsense_Mutation	novel	K1689*	0.1
GBM	chr14	21392663	Frame_Shift_Del	novel	*S2202Wfs5**	0.31
GBM	chr14	21429068	Missense_Mutation	NA	Q371E	0.17
GBM	chr14	21403587	Nonsense_Mutation	novel	M1128delinsIIERNLVLD	0.12
GBM	chr14	21402102	Missense_Mutation	novel	L1306P	0.14
GBM	chr14	21386025	Missense_Mutation	novel	N2445S	0.48
GBM	chr14	21391910	Silent	novel	L2270L	0.42
GBM	chr14	21392728	Missense_Mutation	novel	E2184K	0.06
GBM	chr14	21401431	Missense_Mutation	novel	D1382G	0.33
GBM	chr14	21399628	Missense_Mutation	novel	S1632L	0.25
GBM	chr14	21408371	Missense_Mutation	NA	G891R	0.24
GBM	chr14	21392583	Missense_Mutation	novel	V2232A	0.05
GBM	chr14	21385917	Missense_Mutation	novel	P2481L	0.62
GBM	chr14	21392542	Missense_Mutation	novel	M2246V	0.09
GBM	chr14	21393544	Missense_Mutation	novel	S2084C	0.11
GBM	chr14	21429035	Nonsense_Mutation	novel	Q382*	0.15
GBM	chr14	21405796	Frame_Shift_Del	novel	*H992Lfs34**	0.4
HNSC	chr14	21429328	Missense_Mutation	novel	S284L	0.26
HNSC	chr14	21391543	Missense_Mutation	novel	E2329K	0.22	ResIII
HNSC	chr14	21405864	Nonsense_Mutation	novel	E970*	0.34
HNSC	chr14	21394940	Nonsense_Mutation	novel	E1788*	0.29
HNSC	chr14	21427946	Silent	novel	G508G	0.08
HNSC	chr14	21402497	Missense_Mutation	novel	A1241T	0.41
HNSC	chr14	21402079	Missense_Mutation	novel	A1314P	0.15
HNSC	chr14	21394966	Missense_Mutation	novel	R1779L	0.36
HNSC	chr14	21412998	Splice_Site	novel	X715_splice	0.2
HNSC	chr14	21393639	Frame_Shift_Ins	novel	*L2053Sfs14**	0.21
HNSC	chr14	21394127	Missense_Mutation	novel	I1890V	0.77
HNSC	chr14	21428025	Missense_Mutation	novel	R482P	0.07
HNSC	chr14	21405827	Missense_Mutation	novel	N982S	0.45
HNSC	chr14	21392184	Intron	novel		0.54
HNSC	chr14	21392646	Missense_Mutation	novel	S2211C	0.11
HNSC	chr14	21402474	Missense_Mutation	novel	Q1248H	0.26
HNSC	chr14	21405242	Missense_Mutation	NA	R1092C	0.41
HNSC	chr14	21406999	Missense_Mutation	novel	A922T	0.56
KIRC	chr14	21385919	In_Frame_Ins	novel	A2480_P2481insGGDE	0.05
KIRC	chr14	21385920	Missense_Mutation	novel	A2480G	0.03
KIRC	chr14	21408803	In_Frame_Ins	novel	W796delinsLKDTIFKKNRVCR	0.16
KIRC	chr14	21405794	Missense_Mutation	NA	F993S	0.81
KIRC	chr14	21385646	Silent	NA	A2571A	0.06
KIRP	chr14	21401999	Frame_Shift_Del	novel	*I1341Sfs43**	0.46
KIRP	chr14	21400042	Missense_Mutation	novel	Y1586N	0.3
KIRP	chr14	21400043	Silent	novel	Y1585Y	0.29
KIRP	chr14	21394363	Frame_Shift_Del	novel	*K1838Rfs53**	0.32
KIRP	chr14	21394129	Missense_Mutation	rs777867742	R1889H	0.41
KIRP	chr14	21392551	Frame_Shift_Del	novel	*R2243Afs19**	0.29
KIRP	chr14	21406871	Silent	novel	L964L	0.35
KIRP	chr14	21429295	Missense_Mutation	novel	Q295L	0.03
KIRP	chr14	21394429	Missense_Mutation	NA	E1816V	0.38
LAML	chr14	21430973	Nonsense_Mutation	novel	L224*	0.09
LAML	chr14	21406937	Nonsense_Mutation	novel	W942*	0.27
LGG	chr14	21415891	Missense_Mutation	NA	R578H	0.54
LGG	chr14	21429102	Silent	novel	S359S	0.11
LGG	chr14	21399996	Missense_Mutation	NA	G1601E	0.29
LGG	chr14	21393681	Silent	NA	P2038P	0.07
LGG	chr14	21408309	Splice_Region	novel		0.07
LIHC	chr14	21409886	Missense_Mutation	rs747838726	R777W	0.11
LIHC	chr14	21428150	Silent	NA	S440S	0.33
LIHC	chr14	21385866	Missense_Mutation	novel	H2498P	0.29
LUAD	chr14	21400030	Nonsense_Mutation	NA	E1590*	0.26
LUAD	chr14	21401431	Missense_Mutation	novel	D1382G	0.14
LUAD	chr14	21405273	Missense_Mutation	NA	M1081I	0.38
LUAD	chr14	21395331	Missense_Mutation	NA	D1717Y	0.27
LUAD	chr14	21408802	Nonsense_Mutation	NA	W796*	0.17
LUAD	chr14	21409946	Missense_Mutation	NA	E757Q	0.16
LUAD	chr14	21394134	Silent	rs746231563	L1887L	0.35
LUAD	chr14	21400035	Missense_Mutation	novel	R1588K	0.13
LUAD	chr14	21402505	Splice_Site	novel	X1239_splice	0.15
LUAD	chr14	21399672	Silent	rs764738563	Q1617Q	0.17
LUAD	chr14	21402452	Missense_Mutation	NA	R1256C	0.13
LUAD	chr14	21426240	Splice_Site	novel	X534_splice	0.23
LUAD	chr14	21431105	Missense_Mutation	novel	A180V	0.1
LUAD	chr14	21409986	Splice_Region	rs766074272	P743P	0.28
LUAD	chr14	21428071	Missense_Mutation	NA	E467K	0.13
LUAD	chr14	21394064	Missense_Mutation	novel	A1911S	0.15
LUAD	chr14	21429191	Missense_Mutation	novel	A330S	0.24
LUAD	chr14	21431204	Missense_Mutation	novel	S147I	0.38
LUAD	chr14	21400188	Nonsense_Mutation	NA	E1564*	0.16
LUAD	chr14	21430847	Missense_Mutation	novel	G266V	0.21
LUAD	chr14	21429188	Nonsense_Mutation	novel	Q331*	0.17
LUAD	chr14	21403087	Missense_Mutation	NA	G1215V	0.15
LUAD	chr14	21405320	Nonsense_Mutation	NA	E1066*	0.32
LUAD	chr14	21415792	Missense_Mutation	novel	E611V	0.17
LUAD	chr14	21392217	Intron	novel		0.13
LUAD	chr14	21392644	Missense_Mutation	NA	P2212A	0.09
LUAD	chr14	21394993	Missense_Mutation	NA	A1770V	0.23
LUAD	chr14	21392509	Missense_Mutation	NA	D2257H	0.18
LUAD	chr14	21426129	Missense_Mutation	novel	Q572L	0.14
LUAD	chr14	21393972	Silent	NA	G1941G	0.46
LUAD	chr14	21391565	Silent	novel	V2321V	0.1
LUAD	chr14	21395893	Splice_Site	novel	X1684_splice	0.11
LUAD	chr14	21402053	Silent	novel	G1322G	0.05
LUAD	chr14	21429109	Missense_Mutation	novel	P357L	0.07
LUAD	chr14	21392771	Missense_Mutation	novel	Q2169H	0.07
LUAD	chr14	21415834	Missense_Mutation	NA	E597V	0.24
LUAD	chr14	21429187	Missense_Mutation	NA	Q331L	0.1
LUAD	chr14	21431121	Missense_Mutation	novel	V175L	0.14
LUSC	chr14	21415908	Splice_Site	NA	X573_splice	0.22
LUSC	chr14	21393710	Missense_Mutation	rs145300090	E2029K	0.18
LUSC	chr14	21409949	Frame_Shift_Ins	novel	*Y756Pfs9**	0.31
LUSC	chr14	21394933	Missense_Mutation	novel	A1790V	0.18
LUSC	chr14	21428030	Missense_Mutation	novel	I480M	0.18
LUSC	chr14	21426198	Missense_Mutation	NA	S549L	0.27
LUSC	chr14	21430982	Missense_Mutation	novel	N221I	0.49
LUSC	chr14	21402418	Frame_Shift_Ins	novel	*M1267Rfs20**	0.13
LUSC	chr14	21415829	Missense_Mutation	NA	E599K	0.23
LUSC	chr14	21400897	Missense_Mutation	novel	E1450Q	0.06
LUSC	chr14	21415829	Missense_Mutation	NA	E599K	0.27
LUSC	chr14	21395020	Missense_Mutation	novel	K1761R	0.21
LUSC	chr14	21430822	Silent	novel	T274T	0.24
LUSC	chr14	21412978	Missense_Mutation	NA	P721S	0.58
LUSC	chr14	21431858	5'Flank	novel		0.39
LUSC	chr14	21392779	Missense_Mutation	NA	V2167F	0.27
LUSC	chr14	21391474	Nonsense_Mutation	rs756631600	R2352*	0.19	ResIII
LUSC	chr14	21427955	Missense_Mutation	novel	K505N	0.39
LUSC	chr14	21392778	Missense_Mutation	novel	V2167A	0.35
LUSC	chr14	21430952	Missense_Mutation	novel	N231I	0.25
LUSC	chr14	21415585	Missense_Mutation	novel	V653L	0.31
LUSC	chr14	21400230	Missense_Mutation	NA	D1550N	0.33
MESO	chr14	21402099	Frame_Shift_Del	novel	L1307*	0.33
OV	chr14	21431170	Missense_Mutation	novel	K158N	0.08
OV	chr14	21401419	Missense_Mutation	novel	D1386V	0.15
OV	chr14	21393680	Missense_Mutation	novel	Q2039K	0.04
OV	chr14	21393142	Silent	novel	L2144L	0.19
OV	chr14	21394140	Silent	novel	R1885R	0.1
OV	chr14	21408782	Missense_Mutation	NA	H803R	0.65
OV	chr14	21393677	Missense_Mutation	novel	D2040H	0.12
OV	chr14	21392718	Missense_Mutation	novel	T2187K	0.12
OV	chr14	21405241	Missense_Mutation	NA	R1092H	0.35
OV	chr14	21393487	Missense_Mutation	novel	E2103G	0.32
OV	chr14	21391588	Missense_Mutation	rs371169926	R2314W	0.1	ResIII
OV	chr14	21402374	Missense_Mutation	NA	L1282V	0.39
OV	chr14	21391015	Missense_Mutation	novel	N2372H	0.18
OV	chr14	21428254	Missense_Mutation	NA	A406P	0.73
OV	chr14	21393677	Missense_Mutation	novel	D2040Y	0.07
PAAD	chr14	21393492	Silent	novel	E2101E	0.16
PAAD	chr14	21406962	Missense_Mutation	novel	C934S	0.18
PAAD	chr14	21391508	Nonsense_Mutation	novel	W2340*	0.17	ResIII
PAAD	chr14	21393585	Silent	novel	D2070D	0.11
PAAD	chr14	21395072	Missense_Mutation	novel	A1744T	0.08
PAAD	chr14	21400240	Silent	novel	I1546I	0.22
PAAD	chr14	21400960	Missense_Mutation	rs780639697	R1429W	0.21
PAAD	chr14	21426232	Missense_Mutation	novel	P538S	0.09
PAAD	chr14	21431009	Missense_Mutation	rs771587494	R212Q	0.15
PRAD	chr14	21392546	Silent	NA	R2244R	0.06
PRAD	chr14	21392729	Missense_Mutation	novel	Q2183H	0.16
PRAD	chr14	21393665	Nonsense_Mutation	NA	R2044*	0.33
READ	chr14	21402429	Silent	rs368465266	Y1263Y	0.15
READ	chr14	21401066	Missense_Mutation	NA	N1393K	0.25
READ	chr14	21408450	Silent	novel	V864V	0.08
READ	chr14	21415737	Missense_Mutation	novel	M629I	0.04
READ	chr14	21405309	Missense_Mutation	NA	F1069L	0.45
READ	chr14	21406919	Missense_Mutation	NA	D948E	0.26
READ	chr14	21401029	Missense_Mutation	rs774260771	R1406C	0.31
SARC	chr14	21393685	Missense_Mutation	novel	T2037N	0.21
SARC	chr14	21426244	Splice_Site	novel	X534_splice	0.17
SARC	chr14	21400576	Silent	novel	R1469R	0.1
SKCM	chr14	21405738	Missense_Mutation	NA	L1012F	0.07
SKCM	chr14	21394334	Missense_Mutation	NA	H1848Y	0.45
SKCM	chr14	21400898	Silent	novel	V1449V	0.16
SKCM	chr14	21428131	Missense_Mutation	novel	E447K	0.31
SKCM	chr14	21403635	Silent	NA	F1112F	0.33
SKCM	chr14	21403635	Silent	NA	F1112F	0.18
SKCM	chr14	21392580	Missense_Mutation	NA	S2233I	0.27
SKCM	chr14	21403646	Silent	NA	L1109L	0.67
SKCM	chr14	21408822	Missense_Mutation	rs776528619	R790C	0.23
SKCM	chr14	21393914	Missense_Mutation	novel	R1961C	0.45
SKCM	chr14	21393915	Silent	novel	A1960A	0.46
SKCM	chr14	21393498	Silent	novel	E2099E	0.5
SKCM	chr14	21394029	Missense_Mutation	novel	K1922N	0.27
SKCM	chr14	21401014	Silent	novel	L1411L	0.36
SKCM	chr14	21403033	Missense_Mutation	novel	P1233L	0.3
SKCM	chr14	21403034	Missense_Mutation	novel	P1233S	0.3
SKCM	chr14	21392806	Missense_Mutation	rs371915075	R2158C	0.07
SKCM	chr14	21397892	Missense_Mutation	NA	G1661A	0.19
SKCM	chr14	21408460	Missense_Mutation	novel	P861L	0.13
SKCM	chr14	21408461	Missense_Mutation	novel	P861S	0.12
SKCM	chr14	21428244	Missense_Mutation	NA	S409F	0.11
SKCM	chr14	21430997	Missense_Mutation	NA	S216F	0.18
SKCM	chr14	21409868	Missense_Mutation	NA	P783S	0.09
SKCM	chr14	21405224	Missense_Mutation	NA	P1098S	0.63
SKCM	chr14	21408753	Missense_Mutation	NA	E813K	0.46
SKCM	chr14	21393225	Missense_Mutation	novel	E2117K	0.3
SKCM	chr14	21402076	Missense_Mutation	NA	I1315F	0.11
SKCM	chr14	21415642	Missense_Mutation	NA	E634K	0.38
SKCM	chr14	21401956	Splice_Site	NA	X1354_splice	0.21
SKCM	chr14	21391927	Missense_Mutation	NA	T2264K	0.19
SKCM	chr14	21409931	Missense_Mutation	NA	E762K	0.43
SKCM	chr14	21415782	Silent	rs376100482	L614L	0.61
SKCM	chr14	21429309	Silent	NA	V290V	0.11
SKCM	chr14	21429070	Missense_Mutation	NA	T370I	0.11
SKCM	chr14	21408467	Missense_Mutation	novel	H859Y	0.4
SKCM	chr14	21402432	Silent	novel	S1262S	0.35
SKCM	chr14	21427866	Splice_Region	novel		0.62
SKCM	chr14	21431014	Silent	novel	P210P	0.82
SKCM	chr14	21405307	Missense_Mutation	NA	S1070F	0.38
SKCM	chr14	21391610	Silent	novel	H2306H	0.23
SKCM	chr14	21403478	Silent	novel	L1165L	0.29
SKCM	chr14	21394295	Missense_Mutation	NA	P1861S	0.25
SKCM	chr14	21426234	Missense_Mutation	novel	T537I	0.43
SKCM	chr14	21393820	Missense_Mutation	rs372488156	R1992H	0.26
SKCM	chr14	21427981	Nonsense_Mutation	novel	E497*	0.46
SKCM	chr14	21393752	Nonsense_Mutation	NA	Q2015*	0.53
SKCM	chr14	21402433	Missense_Mutation	NA	S1262F	0.18
SKCM	chr14	21394070	Missense_Mutation	NA	R1909W	0.23
SKCM	chr14	21431124	Missense_Mutation	rs757770866	H174Y	0.48
SKCM	chr14	21403544	Missense_Mutation	novel	P1143S	0.24
SKCM	chr14	21429283	Missense_Mutation	novel	P299L	0.34
SKCM	chr14	21393711	Silent	rs754552862	H2028H	0.39
SKCM	chr14	21393712	Missense_Mutation	novel	H2028L	0.39
SKCM	chr14	21402115	Missense_Mutation	novel	E1302K	0.25
SKCM	chr14	21400541	Missense_Mutation	NA	T1481I	0.26
SKCM	chr14	21402119	Missense_Mutation	novel	K1300N	0.17
SKCM	chr14	21403583	Missense_Mutation	rs376815460	R1130C	0.38
SKCM	chr14	21392792	Silent	NA	N2162N	0.42
SKCM	chr14	21403573	Missense_Mutation	NA	G1133D	0.13
STAD	chr14	21429327	Silent	rs765203840	S284S	0.47
STAD	chr14	21392210	Intron	novel		0.23
STAD	chr14	21428194	Frame_Shift_Ins	novel	E426*	0.32
STAD	chr14	21391527	Missense_Mutation	rs373946888	R2334Q	0.26	ResIII
STAD	chr14	21427993	Missense_Mutation	rs774630592	R493W	0.44
STAD	chr14	21428121	Missense_Mutation	rs774081833	R450H	0.28
STAD	chr14	21394071	Frame_Shift_Ins	novel	*R1909Sfs19**	0.08
STAD	chr14	21392206	Intron	novel		0.09
STAD	chr14	21400267	Frame_Shift_Del	novel	V1538*	0.15
STAD	chr14	21408438	Silent	NA	L868L	0.23
STAD	chr14	21408396	Silent	rs200953445	T882T	0.4
STAD	chr14	21393680	Nonsense_Mutation	NA	Q2039*	0.19
STAD	chr14	21400578	Missense_Mutation	rs375862520	R1469C	0.22
STAD	chr14	21391464	Missense_Mutation	rs752792676	A2355V	0.15
STAD	chr14	21395057	Missense_Mutation	novel	L1749F	0.26
STAD	chr14	21431820	5'Flank	novel		0.11
STAD	chr14	21392611	Missense_Mutation	NA	S2223P	0.06
STAD	chr14	21394129	Missense_Mutation	rs777867742	R1889H	0.23
STAD	chr14	21391902	Silent	rs369570478	A2272A	0.14
STAD	chr14	21405397	Frame_Shift_Del	NA	*N1040Tfs12**	0.24
STAD	chr14	21393816	Silent	NA	T1993T	0.14
STAD	chr14	21428053	Missense_Mutation	NA	R473C	0.38
STAD	chr14	21394129	Missense_Mutation	rs777867742	R1889H	0.28
STAD	chr14	21400605	Nonsense_Mutation	NA	R1460*	0.34
STAD	chr14	21427964	Silent	NA	R502R	0.2
STAD	chr14	21427950	Missense_Mutation	NA	A507V	0.37
STAD	chr14	21402444	In_Frame_Ins	novel	L1257_I1258insMYRL	0.14
STAD	chr14	21431834	5'Flank	novel		0.28
STAD	chr14	21415739	Missense_Mutation	rs757161902	M629V	0.06
STAD	chr14	21402418	Frame_Shift_Ins	novel	*M1267Rfs20**	0.29
STAD	chr14	21393691	Missense_Mutation	rs374379959	R2035Q	0.4
THYM	chr14	21400057	Frame_Shift_Del	novel	*V1581Yfs7**	0.43
UCEC	chr14	21400554	Nonsense_Mutation	NA	R1477*	0.37
UCEC	chr14	21400988	Missense_Mutation	NA	F1419L	0.33
UCEC	chr14	21405738	Missense_Mutation	NA	L1012I	0.33
UCEC	chr14	21414345	Missense_Mutation	NA	R700C	0.31
UCEC	chr14	21428083	Missense_Mutation	NA	R463W	0.03
UCEC	chr14	21427965	Missense_Mutation	rs369696938	R502H	0.31
UCEC	chr14	21426131	Frame_Shift_Ins	novel	*Q572Sfs10**	0.12
UCEC	chr14	21394988	Missense_Mutation	NA	R1772C	0.47
UCEC	chr14	21393665	Nonsense_Mutation	NA	R2044*	0.22
UCEC	chr14	21429099	Silent	rs769647344	S360S	0.15
UCEC	chr14	21394082	Frame_Shift_Del	NA	*L1905Ffs30**	0.15
UCEC	chr14	21408719	Missense_Mutation	novel	F824C	0.06
UCEC	chr14	21385310	3'UTR	rs553509091		0.45
UCEC	chr14	21391510	Missense_Mutation	novel	W2340R	0.36	ResIII
UCEC	chr14	21402379	Missense_Mutation	novel	A1280D	0.41
UCEC	chr14	21429323	Missense_Mutation	rs762427755	R286C	0.37
UCEC	chr14	21391851	Silent	novel	N2289N	0.47
UCEC	chr14	21403648	Frame_Shift_Ins	NA	*I1108Nfs7**	0.41
UCEC	chr14	21429134	Nonsense_Mutation	novel	Q349*	0.04
UCEC	chr14	21391468	Missense_Mutation	NA	L2354I	0.36
UCEC	chr14	21392629	Nonsense_Mutation	novel	R2217*	0.5
UCEC	chr14	21428115	Missense_Mutation	novel	L452W	0.25
UCEC	chr14	21400953	Missense_Mutation	novel	R1431H	0.45
UCEC	chr14	21402452	Missense_Mutation	NA	R1256C	0.41
UCEC	chr14	21415795	Missense_Mutation	novel	P610H	0.39
UCEC	chr14	21428169	Missense_Mutation	novel	A434V	0.43
UCEC	chr14	21391051	Missense_Mutation	novel	R2360C	0.22
UCEC	chr14	21394118	Missense_Mutation	novel	L1893I	0.42
UCEC	chr14	21394448	Missense_Mutation	rs777491813	V1810M	0.39
UCEC	chr14	21402125	Missense_Mutation	novel	F1298L	0.18
UCEC	chr14	21406925	Silent	novel	I946I	0.22
UCEC	chr14	21408413	Nonsense_Mutation	novel	E877*	0.35
UCEC	chr14	21414958	Missense_Mutation	NA	F668L	0.14
UCEC	chr14	21405280	Missense_Mutation	NA	T1079I	0.44
UCEC	chr14	21385771	Missense_Mutation	NA	R2530W	0.17
UCEC	chr14	21393139	Silent	rs748531762	L2145L	0.22
UCEC	chr14	21394163	Missense_Mutation	rs772751525	I1878V	0.11
UCEC	chr14	21402087	Missense_Mutation	NA	A1311V	0.22
UCEC	chr14	21409939	Missense_Mutation	NA	S759N	0.21
UCEC	chr14	21392545	Missense_Mutation	novel	G2245C	0.34
UCEC	chr14	21399678	Silent	novel	V1615V	0.39
UCEC	chr14	21415755	Silent	novel	G623G	0.41
UCEC	chr14	21400580	Missense_Mutation	NA	G1468E	0.46
UCEC	chr14	21402414	Missense_Mutation	NA	F1268L	0.34
UCEC	chr14	21403648	Frame_Shift_Ins	NA	*I1108Nfs7**	0.3
UCEC	chr14	21391016	Frame_Shift_Ins	NA	*N2371Kfs2**	0.47
UCEC	chr14	21385707	Missense_Mutation	NA	S2551Y	0.37
UCEC	chr14	21431137	In_Frame_Ins	novel	S169_V170insQR	0.08
UCEC	chr14	21403103	Missense_Mutation	rs757278444	R1210W	0.42
UCEC	chr14	21401437	Frame_Shift_Del	novel	*K1380Rfs4**	0.17
UCEC	chr14	21405309	Missense_Mutation	NA	F1069L	0.34
UCEC	chr14	21391558	Missense_Mutation	NA	T2324A	0.47	ResIII
UCEC	chr14	21391831	Splice_Site	NA	X2295_splice	0.43
UCEC	chr14	21400500	Missense_Mutation	rs766456579	R1495C	0.12
UCEC	chr14	21405242	Missense_Mutation	NA	R1092C	0.47
UCEC	chr14	21426165	Missense_Mutation	NA	A560V	0.22
UCEC	chr14	21414963	Nonsense_Mutation	novel	E667*	0.45
UCEC	chr14	21405411	Missense_Mutation	novel	E1035D	0.27
UCEC	chr14	21427950	Missense_Mutation	novel	A507D	0.31
UCEC	chr14	21386022	Missense_Mutation	rs763909898	T2446M	0.33
UCEC	chr14	21393711	Silent	rs754552862	H2028H	0.36
UCEC	chr14	21401464	Missense_Mutation	novel	P1371L	0.34
UCEC	chr14	21402494	Nonsense_Mutation	novel	R1242*	0.4
UCEC	chr14	21409886	Missense_Mutation	rs747838726	R777W	0.38
UCEC	chr14	21428065	Missense_Mutation	NA	I469V	0.35
UCEC	chr14	21391017	Frame_Shift_Del	rs751094013	*N2371Ifs6**	0.34
UCEC	chr14	21408416	Nonsense_Mutation	novel	R876*	0.31
UCEC	chr14	21430888	Silent	novel	P252P	0.23
UCEC	chr14	21397880	Missense_Mutation	novel	D1665G	0.34
UCEC	chr14	21385201	3'UTR	novel		0.45
UCEC	chr14	21391003	Missense_Mutation	novel	L2376V	0.06
UCEC	chr14	21394124	Nonsense_Mutation	novel	E1891*	0.18
UCEC	chr14	21385877	Silent	novel	H2494H	0.46
UCEC	chr14	21402440	Missense_Mutation	NA	R1260C	0.54
UCEC	chr14	21394178	Missense_Mutation	novel	L1873M	0.55
UCEC	chr14	21426208	Missense_Mutation	NA	R546C	0.43
UCEC	chr14	21431184	Nonsense_Mutation	novel	Q154*	0.44
UCEC	chr14	21403187	Nonsense_Mutation	novel	R1182*	0.12
UCEC	chr14	21399984	Missense_Mutation	NA	A1605V	0.26
UCEC	chr14	21400240	Silent	novel	I1546I	0.08
UCEC	chr14	21414958	Missense_Mutation	NA	F668L	0.29
UCEC	chr14	21394071	Missense_Mutation	novel	D1908E	0.32
UCEC	chr14	21405322	Missense_Mutation	novel	L1065S	0.43
UCEC	chr14	21414958	Missense_Mutation	NA	F668L	0.33
UCEC	chr14	21385922	Silent	novel	G2479G	0.31
UCEC	chr14	21386138	Silent	novel	P2407P	0.4
UCEC	chr14	21402429	Silent	rs368465266	Y1263Y	0.29
UCEC	chr14	21429035	Nonsense_Mutation	novel	Q382*	0.29
UCEC	chr14	21392573	Silent	NA	A2235A	0.13
UCEC	chr14	21401029	Missense_Mutation	rs774260771	R1406C	0.18
UCEC	chr14	21394477	Missense_Mutation	novel	R1800K	0.41
UCEC	chr14	21400569	Nonsense_Mutation	NA	R1472*	0.1
UCEC	chr14	21386101	Missense_Mutation	rs371294659	R2420C	0.46
UCEC	chr14	21427945	Frame_Shift_Del	novel	*E509Rfs3**	0.35
UCEC	chr14	21415590	Missense_Mutation	NA	R651Q	0.2
UCEC	chr14	21427937	In_Frame_Ins	novel	K512_E513insNPREK	0.01
UCEC	chr14	21385771	Missense_Mutation	NA	R2530W	0.33
UCEC	chr14	21394061	Missense_Mutation	novel	L1912V	0.33
UCEC	chr14	21405311	Missense_Mutation	novel	F1069V	0.31
UCEC	chr14	21427898	Silent	novel	A524A	0.33
UCEC	chr14	21394423	Missense_Mutation	rs371906576	D1818G	0.2
UCEC	chr14	21428082	Missense_Mutation	novel	R463Q	0.45
UCEC	chr14	21403103	Missense_Mutation	rs757278444	R1210W	0.46
UCEC	chr14	21402498	Missense_Mutation	novel	Q1240H	0.19
UCEC	chr14	21408416	Nonsense_Mutation	novel	R876*	0.33
UCEC	chr14	21400060	Missense_Mutation	NA	R1580W	0.21
UCEC	chr14	21405381	Missense_Mutation	novel	Q1045H	0.42
UCEC	chr14	21426155	Silent	novel	P563P	0.56
UCEC	chr14	21394988	Missense_Mutation	NA	R1772C	0.45
UCEC	chr14	21409990	Splice_Site	NA	X743_splice	0.32
UCEC	chr14	21405760	Silent	novel	E1004E	0.27
UCEC	chr14	21403647	Silent	NA	I1108I	0.32
UCEC	chr14	21426165	Missense_Mutation	NA	A560V	0.11
UCEC	chr14	21400183	Missense_Mutation	novel	S1565R	0.14
UCEC	chr14	21405402	Missense_Mutation	novel	E1038D	0.17
UCEC	chr14	21385471	3'UTR	novel		0.83
UCEC	chr14	21393923	Missense_Mutation	novel	L1958M	0.29
UCEC	chr14	21400613	Splice_Site	novel	X1457_splice	0.25
UCEC	chr14	21393770	Missense_Mutation	novel	P2009S	0.23
UCEC	chr14	21394930	Missense_Mutation	rs370298280	R1791Q	0.09
UCEC	chr14	21391589	Silent	NA	T2313T	0.24
UCEC	chr14	21395051	Missense_Mutation	novel	R1751C	0.07
UCEC	chr14	21401064	Frame_Shift_Del	novel	*L1394Wfs2**	0.39
UCEC	chr14	21406936	Missense_Mutation	NA	R943C	0.13
UCEC	chr14	21395080	Missense_Mutation	rs749428842	P1741L	0.47
UCEC	chr14	21393749	Missense_Mutation	novel	V2016F	0.37
UCEC	chr14	21405225	Silent	novel	H1097H	0.31
UCEC	chr14	21391016	Frame_Shift_Ins	NA	*N2371Kfs2**	0.36
UCEC	chr14	21392658	Missense_Mutation	novel	E2207G	0.25
UCEC	chr14	21394967	Missense_Mutation	NA	R1779C	0.37
UCEC	chr14	21406908	Missense_Mutation	novel	R952Q	0.07
UCEC	chr14	21402347	Missense_Mutation	NA	N1291D	0.39
UCEC	chr14	21394141	Missense_Mutation	novel	R1885Q	0.38
UCEC	chr14	21429127	Frame_Shift_Ins	NA	*I351Nfs70**	0.36
UCEC	chr14	21414958	Missense_Mutation	NA	F668L	0.37
UCEC	chr14	21408495	Missense_Mutation	novel	F849L	0.07
UCEC	chr14	21391903	Missense_Mutation	rs745726816	A2272V	0.17
UCEC	chr14	21399666	Missense_Mutation	novel	E1619D	0.19
UCEC	chr14	21403163	Missense_Mutation	novel	A1190S	0.21
UCEC	chr14	21403514	Missense_Mutation	novel	L1153M	0.41
UCEC	chr14	21408429	Silent	novel	I871I	0.45
UCEC	chr14	21415596	Missense_Mutation	novel	S649Y	0.18
UCEC	chr14	21415897	Missense_Mutation	novel	S576L	0.18
UCEC	chr14	21426208	Missense_Mutation	NA	R546C	0.12
UCEC	chr14	21431818	5'Flank	novel		0.14
UCEC	chr14	21405756	Missense_Mutation	novel	L1006I	0.39
UCEC	chr14	21394454	Nonsense_Mutation	NA	R1808*	0.31
UCEC	chr14	21395029	Missense_Mutation	rs755975357	R1758H	0.31
UCEC	chr14	21429321	Silent	NA	R286R	0.26
UCEC	chr14	21400273	Silent	rs748561663	G1535G	0.41
UCEC	chr14	21392574	Missense_Mutation	rs377559805	A2235V	0.38
UCEC	chr14	21394454	Nonsense_Mutation	NA	R1808*	0.32
UCEC	chr14	21403203	Silent	novel	Y1176Y	0.29
UCEC	chr14	21385707	Missense_Mutation	NA	S2551Y	0.29
UCEC	chr14	21427883	Silent	novel	G529G	0.39
UCEC	chr14	21393665	Nonsense_Mutation	NA	R2044*	0.4
UCS	chr14	21391551	Missense_Mutation	novel	L2326R	0.29	ResIII
UCS	chr14	21402060	Missense_Mutation	novel	D1320G	0.43
UCS	chr14	21402488	Missense_Mutation	novel	H1244N	0.27

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	AMP	0.2778	0.056464
ACC	DEL	0.1444	0.19769
CHOL	DEL	0.3611	0.00040262
HNSC	DEL	0.1169	0.0025503
KIRP	DEL	0.1667	0.085174
LUSC	DEL	0.2655	0.0082553
PAAD	DEL	0.087	0.11332

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
ACC	0.0057	Kaplan-Meier Survival Analysis
BLCA	0.042	Kaplan-Meier Survival Analysis
CESC	0.037	Kaplan-Meier Survival Analysis
KICH	0.015	Kaplan-Meier Survival Analysis
LIHC	0.0099	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.025	Kaplan-Meier Survival Analysis
UVM	0.0069	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000100888 (Gene tree)
Gene ID: 57680
Gene Symbol: CHD8
Alias: KIAA1564|DUPLIN|HELSNF1
Full Name: chromodomain helicase DNA binding protein 8
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 70,933 bases
Position: chr14:21,385,194-21,456,126
Accession: 20153
RBP type: canonical RBP
Summary: This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000493865	ResIII	PF04851.15	5.3e-08	1	1
ENSP00000496730	ResIII	PF04851.15	1.6e-07	1	1
ENSP00000451442	ResIII	PF04851.15	1.7e-07	1	1
ENSP00000406288	ResIII	PF04851.15	1.8e-07	1	1
ENSP00000494402	ResIII	PF04851.15	1.8e-07	1	1
ENSP00000382863	ResIII	PF04851.15	2.4e-07	1	1
ENSP00000451601	ResIII	PF04851.15	2.4e-07	1	1
ENSP00000495070	ResIII	PF04851.15	2.4e-07	1	1
ENSP00000495240	ResIII	PF04851.15	2.4e-07	1	1
ENSP00000451442	BRK	PF07533.16	2.4e-15	1	1
ENSP00000406288	BRK	PF07533.16	3.3e-15	1	1
ENSP00000494402	BRK	PF07533.16	3.3e-15	1	1
ENSP00000382863	BRK	PF07533.16	3.8e-15	1	1
ENSP00000451601	BRK	PF07533.16	3.8e-15	1	1
ENSP00000495070	BRK	PF07533.16	3.8e-15	1	1
ENSP00000495240	BRK	PF07533.16	3.8e-15	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25294932	CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.	Proc Natl Acad Sci U S A	2014 Oct 21	Sugathan A	doi: 10.1073/pnas.1405266111
28671691	Germline Chd8 haploinsufficiency alters brain development in mouse.	Nat Neurosci	2017 Aug	Gompers AL	doi: 10.1038/nn.4592

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000646063	CHD8-222	1852	-	ENSP00000496565	586 (aa)	-	A0A2R8Y808
ENST00000553283	CHD8-203	543	-	ENSP00000450860	98 (aa)	-	G3V2T9
ENST00000557329	CHD8-212	578	-	-	- (aa)	-	-
ENST00000555962	CHD8-210	1343	-	ENSP00000495174	102 (aa)	-	A0A2R8YFI9
ENST00000430710	CHD8-202	7422	-	ENSP00000406288	2302 (aa)	-	Q9HCK8
ENST00000556833	CHD8-211	416	-	-	- (aa)	-	-
ENST00000643469	CHD8-218	8259	-	ENSP00000495070	2581 (aa)	-	Q9HCK8
ENST00000553622	CHD8-204	633	-	ENSP00000450957	151 (aa)	-	G3V303
ENST00000399982	CHD8-201	8229	-	ENSP00000382863	2581 (aa)	-	Q9HCK8
ENST00000643048	CHD8-217	2815	-	-	- (aa)	-	-
ENST00000557364	CHD8-213	8163	-	ENSP00000451601	2581 (aa)	-	Q9HCK8
ENST00000642914	CHD8-216	2818	-	-	- (aa)	-	-
ENST00000645206	CHD8-220	7314	-	-	- (aa)	-	-
ENST00000646647	CHD8-225	8471	-	ENSP00000495240	2581 (aa)	-	Q9HCK8
ENST00000646558	CHD8-224	5001	-	-	- (aa)	-	-
ENST00000555935	CHD8-209	5458	-	ENSP00000451442	1815 (aa)	-	H0YJG4
ENST00000645929	CHD8-221	7422	-	ENSP00000494402	2302 (aa)	-	Q9HCK8
ENST00000554384	CHD8-207	735	-	-	- (aa)	-	-
ENST00000553870	CHD8-206	1174	-	ENSP00000451071	372 (aa)	-	H0YJA4
ENST00000557727	CHD8-214	1146	-	-	- (aa)	-	-
ENST00000555301	CHD8-208	918	-	-	- (aa)	-	-
ENST00000645140	CHD8-219	3613	-	ENSP00000493865	1102 (aa)	-	A0A2R8Y4P3
ENST00000553651	CHD8-205	5583	-	-	- (aa)	-	-
ENST00000646340	CHD8-223	6144	-	ENSP00000496730	1995 (aa)	-	A0A2R8Y840
ENST00000642518	CHD8-215	1104	-	ENSP00000496722	305 (aa)	-	A0A2R8YFT4

Gene Model

Click here to download ENSG00000100888's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04310	Wnt signaling pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000100888's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000100888	CHD8	86	85.393	ENSAPOG00000015560	chd8	82	60.532	Acanthochromis_polyacanthus
ENSG00000100888	CHD8	87	84.270	ENSAPOG00000009351	chd7	64	62.150	Acanthochromis_polyacanthus
ENSG00000100888	CHD8	86	86.364	ENSAMEG00000005699	CHD7	58	68.915	Ailuropoda_melanoleuca
ENSG00000100888	CHD8	100	98.183	ENSAMEG00000006307	CHD8	100	98.183	Ailuropoda_melanoleuca
ENSG00000100888	CHD8	86	84.444	ENSACIG00000006440	chd8	89	62.137	Amphilophus_citrinellus
ENSG00000100888	CHD8	86	85.227	ENSACIG00000001590	chd7	60	71.288	Amphilophus_citrinellus
ENSG00000100888	CHD8	86	85.393	ENSAOCG00000016793	chd8	89	61.441	Amphiprion_ocellaris
ENSG00000100888	CHD8	86	85.227	ENSAOCG00000002337	chd7	60	72.155	Amphiprion_ocellaris
ENSG00000100888	CHD8	87	85.393	ENSAPEG00000010332	chd7	50	66.517	Amphiprion_percula
ENSG00000100888	CHD8	86	85.393	ENSATEG00000007108	chd8	90	60.658	Anabas_testudineus
ENSG00000100888	CHD8	86	85.227	ENSATEG00000002590	chd7	68	70.309	Anabas_testudineus
ENSG00000100888	CHD8	86	86.364	ENSAPLG00000005873	CHD7	65	63.479	Anas_platyrhynchos
ENSG00000100888	CHD8	86	95.455	ENSACAG00000003139	CHD8	90	74.702	Anolis_carolinensis
ENSG00000100888	CHD8	86	86.364	ENSACAG00000005760	CHD7	58	69.231	Anolis_carolinensis
ENSG00000100888	CHD8	86	86.364	ENSANAG00000035300	CHD7	65	69.000	Aotus_nancymaae
ENSG00000100888	CHD8	100	99.348	ENSANAG00000037714	CHD8	100	99.348	Aotus_nancymaae
ENSG00000100888	CHD8	86	85.393	ENSACLG00000019692	chd8	93	64.941	Astatotilapia_calliptera
ENSG00000100888	CHD8	86	85.227	ENSAMXG00000006180	chd7	60	67.366	Astyanax_mexicanus
ENSG00000100888	CHD8	86	86.364	ENSBTAG00000021841	CHD7	62	68.945	Bos_taurus
ENSG00000100888	CHD8	100	98.567	ENSBTAG00000020422	CHD8	100	98.567	Bos_taurus
ENSG00000100888	CHD8	100	99.344	ENSCJAG00000009002	CHD8	100	99.219	Callithrix_jacchus
ENSG00000100888	CHD8	86	86.364	ENSCJAG00000009025	CHD7	60	67.114	Callithrix_jacchus
ENSG00000100888	CHD8	100	98.183	ENSCAFG00000005626	CHD8	100	98.500	Canis_familiaris
ENSG00000100888	CHD8	86	86.364	ENSCAFG00000007167	CHD7	62	68.804	Canis_familiaris
ENSG00000100888	CHD8	100	98.481	ENSCAFG00020014565	CHD8	100	98.481	Canis_lupus_dingo
ENSG00000100888	CHD8	86	86.364	ENSCAFG00020015856	CHD7	61	68.432	Canis_lupus_dingo
ENSG00000100888	CHD8	100	98.490	ENSCHIG00000026157	CHD8	100	98.490	Capra_hircus
ENSG00000100888	CHD8	86	86.364	ENSCHIG00000011729	CHD7	60	66.815	Capra_hircus
ENSG00000100888	CHD8	86	86.364	ENSTSYG00000004018	CHD7	57	69.000	Carlito_syrichta
ENSG00000100888	CHD8	100	98.340	ENSTSYG00000011939	CHD8	100	98.340	Carlito_syrichta
ENSG00000100888	CHD8	86	86.364	ENSCAPG00000007952	CHD7	57	65.189	Cavia_aperea
ENSG00000100888	CHD8	99	96.711	ENSCAPG00000016749	CHD8	99	90.680	Cavia_aperea
ENSG00000100888	CHD8	99	98.345	ENSCPOG00000002538	CHD8	100	97.020	Cavia_porcellus
ENSG00000100888	CHD8	86	86.364	ENSCPOG00000013385	CHD7	58	68.738	Cavia_porcellus
ENSG00000100888	CHD8	100	99.435	ENSCCAG00000020467	CHD8	100	99.435	Cebus_capucinus
ENSG00000100888	CHD8	86	86.364	ENSCCAG00000025831	CHD7	58	68.867	Cebus_capucinus
ENSG00000100888	CHD8	86	86.364	ENSCATG00000020229	CHD7	65	69.067	Cercocebus_atys
ENSG00000100888	CHD8	100	99.652	ENSCATG00000004861	CHD8	100	99.652	Cercocebus_atys
ENSG00000100888	CHD8	86	86.364	ENSCLAG00000004679	CHD7	66	62.605	Chinchilla_lanigera
ENSG00000100888	CHD8	99	98.746	ENSCLAG00000001966	CHD8	100	97.445	Chinchilla_lanigera
ENSG00000100888	CHD8	86	86.364	ENSCSAG00000014349	CHD7	58	68.954	Chlorocebus_sabaeus
ENSG00000100888	CHD8	99	99.448	ENSCSAG00000016489	CHD8	100	99.225	Chlorocebus_sabaeus
ENSG00000100888	CHD8	99	95.862	ENSCHOG00000003782	CHD8	100	93.015	Choloepus_hoffmanni
ENSG00000100888	CHD8	86	86.364	ENSCHOG00000008478	CHD7	64	84.801	Choloepus_hoffmanni
ENSG00000100888	CHD8	95	91.096	ENSCPBG00000012687	CHD8	98	82.042	Chrysemys_picta_bellii
ENSG00000100888	CHD8	86	86.364	ENSCPBG00000021517	CHD7	77	70.580	Chrysemys_picta_bellii
ENSG00000100888	CHD8	86	67.778	ENSCSAVG00000005900	-	100	64.832	Ciona_savignyi
ENSG00000100888	CHD8	86	86.364	ENSCANG00000041382	CHD7	58	68.933	Colobus_angolensis_palliatus
ENSG00000100888	CHD8	100	99.609	ENSCANG00000042948	CHD8	100	99.609	Colobus_angolensis_palliatus
ENSG00000100888	CHD8	99	97.792	ENSCGRG00001014351	Chd8	100	96.437	Cricetulus_griseus_chok1gshd
ENSG00000100888	CHD8	86	86.364	ENSCGRG00001011949	Chd7	65	69.169	Cricetulus_griseus_chok1gshd
ENSG00000100888	CHD8	99	97.792	ENSCGRG00000009710	Chd8	100	96.437	Cricetulus_griseus_crigri
ENSG00000100888	CHD8	86	86.364	ENSCGRG00000000481	Chd7	66	64.098	Cricetulus_griseus_crigri
ENSG00000100888	CHD8	86	83.146	ENSCSEG00000021155	chd8	82	61.702	Cynoglossus_semilaevis
ENSG00000100888	CHD8	87	84.270	ENSCSEG00000017886	chd7	62	64.861	Cynoglossus_semilaevis
ENSG00000100888	CHD8	86	85.227	ENSCVAG00000017584	chd7	50	66.816	Cyprinodon_variegatus
ENSG00000100888	CHD8	87	85.393	ENSDARG00000075211	chd7	72	67.785	Danio_rerio
ENSG00000100888	CHD8	86	83.146	ENSDARG00000075543	chd8	87	68.948	Danio_rerio
ENSG00000100888	CHD8	100	97.910	ENSDNOG00000005838	CHD8	100	97.910	Dasypus_novemcinctus
ENSG00000100888	CHD8	86	86.364	ENSDNOG00000011674	CHD7	65	68.779	Dasypus_novemcinctus
ENSG00000100888	CHD8	86	86.364	ENSDORG00000003515	Chd7	58	68.954	Dipodomys_ordii
ENSG00000100888	CHD8	99	96.638	ENSDORG00000002050	Chd8	98	96.413	Dipodomys_ordii
ENSG00000100888	CHD8	100	96.393	ENSETEG00000012353	CHD8	96	93.835	Echinops_telfairi
ENSG00000100888	CHD8	86	85.227	ENSEBUG00000007607	chd8	82	60.261	Eptatretus_burgeri
ENSG00000100888	CHD8	86	86.364	ENSEASG00005016258	CHD7	58	69.092	Equus_asinus_asinus
ENSG00000100888	CHD8	100	98.785	ENSEASG00005010882	CHD8	100	98.785	Equus_asinus_asinus
ENSG00000100888	CHD8	100	98.606	ENSECAG00000016102	CHD8	100	98.606	Equus_caballus
ENSG00000100888	CHD8	86	86.364	ENSECAG00000001445	CHD7	65	69.092	Equus_caballus
ENSG00000100888	CHD8	86	86.364	ENSEEUG00000013559	CHD7	51	78.298	Erinaceus_europaeus
ENSG00000100888	CHD8	99	96.552	ENSEEUG00000003523	CHD8	81	100.000	Erinaceus_europaeus
ENSG00000100888	CHD8	86	82.955	ENSELUG00000024442	chd7	60	63.320	Esox_lucius
ENSG00000100888	CHD8	86	84.444	ENSELUG00000004302	chd8	90	63.329	Esox_lucius
ENSG00000100888	CHD8	86	86.364	ENSFCAG00000003849	CHD7	58	68.879	Felis_catus
ENSG00000100888	CHD8	100	98.490	ENSFCAG00000013859	CHD8	100	98.911	Felis_catus
ENSG00000100888	CHD8	86	86.364	ENSFALG00000005570	CHD7	64	63.360	Ficedula_albicollis
ENSG00000100888	CHD8	99	98.545	ENSFDAG00000011368	CHD8	100	97.446	Fukomys_damarensis
ENSG00000100888	CHD8	86	86.364	ENSFDAG00000000528	CHD7	59	67.873	Fukomys_damarensis
ENSG00000100888	CHD8	86	85.227	ENSFHEG00000001311	chd7	50	66.344	Fundulus_heteroclitus
ENSG00000100888	CHD8	86	81.818	ENSGMOG00000004232	chd7	60	70.190	Gadus_morhua
ENSG00000100888	CHD8	86	81.111	ENSGMOG00000015075	chd8	94	67.831	Gadus_morhua
ENSG00000100888	CHD8	86	86.364	ENSGALG00000041080	CHD7	59	66.433	Gallus_gallus
ENSG00000100888	CHD8	86	80.899	ENSGAFG00000015210	-	98	70.692	Gambusia_affinis
ENSG00000100888	CHD8	87	84.270	ENSGAFG00000006858	chd7	59	66.816	Gambusia_affinis
ENSG00000100888	CHD8	86	84.091	ENSGACG00000014897	chd7	62	69.543	Gasterosteus_aculeatus
ENSG00000100888	CHD8	86	83.333	ENSGACG00000014096	chd8	82	69.029	Gasterosteus_aculeatus
ENSG00000100888	CHD8	95	89.695	ENSGAGG00000022951	CHD8	99	85.354	Gopherus_agassizii
ENSG00000100888	CHD8	87	85.393	ENSGAGG00000017996	CHD7	82	70.242	Gopherus_agassizii
ENSG00000100888	CHD8	86	86.364	ENSGGOG00000012224	CHD7	58	69.067	Gorilla_gorilla
ENSG00000100888	CHD8	100	100.000	ENSGGOG00000002251	CHD8	100	99.957	Gorilla_gorilla
ENSG00000100888	CHD8	86	85.393	ENSHBUG00000002850	chd8	89	61.567	Haplochromis_burtoni
ENSG00000100888	CHD8	86	86.364	ENSHGLG00000017268	CHD7	65	63.846	Heterocephalus_glaber_female
ENSG00000100888	CHD8	99	98.645	ENSHGLG00000003559	CHD8	100	97.638	Heterocephalus_glaber_female
ENSG00000100888	CHD8	99	98.645	ENSHGLG00100001031	CHD8	100	97.638	Heterocephalus_glaber_male
ENSG00000100888	CHD8	86	86.364	ENSHGLG00100015649	CHD7	58	69.354	Heterocephalus_glaber_male
ENSG00000100888	CHD8	86	82.955	ENSHCOG00000016611	chd8	91	62.941	Hippocampus_comes
ENSG00000100888	CHD8	86	85.227	ENSHCOG00000014380	chd7	58	72.578	Hippocampus_comes
ENSG00000100888	CHD8	86	80.899	ENSIPUG00000019891	chd8	90	61.804	Ictalurus_punctatus
ENSG00000100888	CHD8	86	85.227	ENSIPUG00000007585	chd7	81	63.425	Ictalurus_punctatus
ENSG00000100888	CHD8	86	86.364	ENSSTOG00000011949	CHD7	60	67.178	Ictidomys_tridecemlineatus
ENSG00000100888	CHD8	100	97.909	ENSSTOG00000001854	CHD8	100	97.909	Ictidomys_tridecemlineatus
ENSG00000100888	CHD8	86	86.364	ENSJJAG00000022064	Chd7	57	69.267	Jaculus_jaculus
ENSG00000100888	CHD8	99	98.093	ENSJJAG00000000408	Chd8	100	96.752	Jaculus_jaculus
ENSG00000100888	CHD8	86	84.270	ENSKMAG00000020106	chd8	89	60.691	Kryptolebias_marmoratus
ENSG00000100888	CHD8	86	85.227	ENSKMAG00000009724	chd7	50	66.617	Kryptolebias_marmoratus
ENSG00000100888	CHD8	99	76.843	ENSLACG00000011367	CHD8	79	76.297	Latimeria_chalumnae
ENSG00000100888	CHD8	86	85.227	ENSLACG00000002461	CHD7	66	63.475	Latimeria_chalumnae
ENSG00000100888	CHD8	86	85.227	ENSLOCG00000005062	chd7	64	61.190	Lepisosteus_oculatus
ENSG00000100888	CHD8	99	99.310	ENSLAFG00000009358	CHD8	100	97.754	Loxodonta_africana
ENSG00000100888	CHD8	86	86.364	ENSLAFG00000000403	CHD7	67	67.497	Loxodonta_africana
ENSG00000100888	CHD8	100	99.652	ENSMFAG00000035402	CHD8	100	99.652	Macaca_fascicularis
ENSG00000100888	CHD8	86	86.364	ENSMFAG00000041825	CHD7	59	69.067	Macaca_fascicularis
ENSG00000100888	CHD8	100	99.609	ENSMMUG00000015002	CHD8	100	99.609	Macaca_mulatta
ENSG00000100888	CHD8	86	86.364	ENSMMUG00000011584	CHD7	58	69.067	Macaca_mulatta
ENSG00000100888	CHD8	100	99.566	ENSMNEG00000031076	CHD8	100	99.566	Macaca_nemestrina
ENSG00000100888	CHD8	86	86.364	ENSMNEG00000040978	CHD7	58	69.000	Macaca_nemestrina
ENSG00000100888	CHD8	86	86.364	ENSMLEG00000038817	CHD7	58	69.067	Mandrillus_leucophaeus
ENSG00000100888	CHD8	100	99.652	ENSMLEG00000035911	CHD8	100	99.652	Mandrillus_leucophaeus
ENSG00000100888	CHD8	86	83.333	ENSMAMG00000016297	chd8	89	60.350	Mastacembelus_armatus
ENSG00000100888	CHD8	86	85.393	ENSMZEG00005012027	chd8	89	62.030	Maylandia_zebra
ENSG00000100888	CHD8	86	86.364	ENSMGAG00000011092	CHD7	59	66.838	Meleagris_gallopavo
ENSG00000100888	CHD8	86	86.364	ENSMAUG00000001000	Chd7	67	66.818	Mesocricetus_auratus
ENSG00000100888	CHD8	96	95.222	ENSMAUG00000015827	Chd8	100	88.936	Mesocricetus_auratus
ENSG00000100888	CHD8	86	86.364	ENSMICG00000002430	CHD7	58

EuRBPDB

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Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

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