EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chrX	100838280	Missense_Mutation	novel	Q551H	0.15
BLCA	chrX	100822317	Silent	novel	E68E	0.88
BLCA	chrX	100820407	5'UTR	novel		0.44
BLCA	chrX	100831649	Missense_Mutation	novel	E342K	0.11
BLCA	chrX	100831631	Frame_Shift_Ins	novel	*S336Yfs9**	0.07
BLCA	chrX	100831632	Missense_Mutation	novel	S336F	0.08
BLCA	chrX	100831643	Missense_Mutation	novel	E340Q	0.09
BLCA	chrX	100831580	Silent	NA	R319R	0.85
BLCA	chrX	100833263	Missense_Mutation	NA	E431K	0.82
BRCA	chrX	100832886	Missense_Mutation	novel	R395M	0.6
BRCA	chrX	100823993	Silent	rs781187830	P184P	0.2
CESC	chrX	100826735	Silent	NA	G268G	0.47
CESC	chrX	100833447	Missense_Mutation	rs139392902	A492V	0.33
CESC	chrX	100833360	Missense_Mutation	novel	R463K	0.08
CESC	chrX	100832799	Missense_Mutation	NA	G366V	0.33
CESC	chrX	100822250	Splice_Site	NA	X46_splice	0.45
CESC	chrX	100821587	Missense_Mutation	novel	G40V	0.08	RRM_1
CESC	chrX	100821589	In_Frame_Del	novel	P41del	0.08	RRM_1
CESC	chrX	100826744	Silent	NA	S271S	0.14
COAD	chrX	100833470	Nonsense_Mutation	NA	Q500*	0.48
COAD	chrX	100833209	Nonsense_Mutation	rs748719204	R413*	0.34
COAD	chrX	100820456	Missense_Mutation	novel	S14P	0.26	RRM_1
COAD	chrX	100832860	Silent	novel	E386E	0.08
COAD	chrX	100838258	Missense_Mutation	NA	V544A	0.2
COAD	chrX	100821531	Silent	NA	G21G	0.19
COAD	chrX	100833285	Missense_Mutation	rs767318301	R438H	0.23
COAD	chrX	100833318	Missense_Mutation	NA	A449V	0.18
ESCA	chrX	100824184	Missense_Mutation	novel	G210D	0.39
ESCA	chrX	100833358	Silent	novel	A462A	0.41
GBM	chrX	100820446	Silent	NA	A10A	0.34
GBM	chrX	100833299	Missense_Mutation	rs749587180	R443C	0.77
GBM	chrX	100820366	5'Flank	novel		0.75
GBM	chrX	100824216	Missense_Mutation	novel	M221L	0.22
GBM	chrX	100820421	Missense_Mutation	NA	A2V	0.28
HNSC	chrX	100832849	Missense_Mutation	novel	L383I	0.35
HNSC	chrX	100823994	Missense_Mutation	novel	E185K	0.36
LAML	chrX	100837400	Missense_Mutation	novel	G521D	0.11
LGG	chrX	100822412	Missense_Mutation	NA	E100V	0.29
LGG	chrX	100820445	Missense_Mutation	novel	A10V	0.23
LGG	chrX	100826708	Missense_Mutation	novel	Q259H	0.15
LIHC	chrX	100823306	Missense_Mutation	NA	A108S	0.17
LIHC	chrX	100831594	Silent	NA	G323G	0.48
LUAD	chrX	100823987	Silent	NA	V182V	0.29
LUAD	chrX	100831583	Missense_Mutation	novel	G320C	0.4
LUAD	chrX	100838262	Silent	novel	L545L	0.21
LUAD	chrX	100820420	Missense_Mutation	novel	A2T	0.31
LUAD	chrX	100832756	Missense_Mutation	novel	Q352E	0.11
LUAD	chrX	100832806	Silent	NA	P368P	0.45
LUAD	chrX	100823913	Missense_Mutation	NA	A158P	0.27
LUAD	chrX	100831561	Silent	NA	P312P	0.06
LUSC	chrX	100831575	Missense_Mutation	novel	T317N	0.35
LUSC	chrX	100822371	Silent	NA	A86A	0.75
LUSC	chrX	100820419	Translation_Start_Site	novel	M1?	0.2
LUSC	chrX	100820420	Missense_Mutation	novel	A2S	0.19
LUSC	chrX	100823371	Missense_Mutation	novel	S129R	0.1
LUSC	chrX	100831620	Missense_Mutation	novel	G332A	0.36
LUSC	chrX	100822306	Missense_Mutation	NA	Q65E	0.11	RRM_1
LUSC	chrX	100833386	Missense_Mutation	novel	P472S	0.76
LUSC	chrX	100824119	Splice_Site	novel	X189_splice	0.21
LUSC	chrX	100832747	Missense_Mutation	NA	P349T	0.16
OV	chrX	100828093	Missense_Mutation	NA	R294W	0.06
PAAD	chrX	100823992	Missense_Mutation	NA	P184L	0.11
READ	chrX	100822260	Silent	rs766161610	Y49Y	0.83
SKCM	chrX	100832739	Missense_Mutation	NA	Y346F	0.84
SKCM	chrX	100823330	Missense_Mutation	novel	G116R	0.41
SKCM	chrX	100828070	Missense_Mutation	novel	G286E	0.45
SKCM	chrX	100837363	Missense_Mutation	NA	M509L	0.58
SKCM	chrX	100822337	Missense_Mutation	novel	R75Q	0.3	RRM_1
SKCM	chrX	100822338	Silent	novel	R75R	0.3
SKCM	chrX	100820397	5'Flank	novel		0.36
SKCM	chrX	100823294	Missense_Mutation	NA	L104F	0.9
SKCM	chrX	100822331	Missense_Mutation	novel	A73V	0.83	RRM_1
SKCM	chrX	100820370	5'Flank	novel		0.19
SKCM	chrX	100832740	Silent	novel	Y346Y	0.5
SKCM	chrX	100820375	5'Flank	novel		0.15
SKCM	chrX	100833245	Silent	NA	L425L	0.39
SKCM	chrX	100831601	Missense_Mutation	novel	P326S	0.77
STAD	chrX	100823942	Missense_Mutation	NA	Q167H	0.06
STAD	chrX	100824188	Silent	NA	A211A	0.4
STAD	chrX	100820415	5'UTR	novel		0.26
STAD	chrX	100833285	Missense_Mutation	rs767318301	R438H	0.52
STAD	chrX	100823964	Missense_Mutation	NA	A175P	0.74
STAD	chrX	100822260	Silent	rs766161610	Y49Y	0.47
STAD	chrX	100822391	Missense_Mutation	NA	A93V	0.23
STAD	chrX	100823893	Missense_Mutation	NA	V151A	0.17
UCEC	chrX	100822375	Nonsense_Mutation	NA	R88*	0.32
UCEC	chrX	100821596	Missense_Mutation	novel	V43A	0.49	RRM_1
UCEC	chrX	100833454	Frame_Shift_Del	novel	*Q496Rfs45**	0.08
UCEC	chrX	100833344	Nonsense_Mutation	novel	R458*	0.31
UCEC	chrX	100820473	Missense_Mutation	NA	F19L	0.43	RRM_1
UCEC	chrX	100826755	Missense_Mutation	NA	G275E	0.41
UCEC	chrX	100838328	Missense_Mutation	NA	K567N	0.47
UCEC	chrX	100833263	In_Frame_Del	rs779138581	A452_E456del	0.34
UCEC	chrX	100823334	Missense_Mutation	novel	E117G	0.29
UCEC	chrX	100826734	Missense_Mutation	novel	G268V	0.3
UCEC	chrX	100831564	Silent	rs148091932	A313A	0.22
UCEC	chrX	100832837	Missense_Mutation	NA	E379K	0.24
UCEC	chrX	100820453	Missense_Mutation	NA	R13C	0.2	RRM_1
UCEC	chrX	100833285	Missense_Mutation	rs767318301	R438H	0.22
UCEC	chrX	100824178	Missense_Mutation	novel	V208A	0.15
UCEC	chrX	100833235	Missense_Mutation	novel	E421D	0.18
UCEC	chrX	100832837	Missense_Mutation	NA	E379K	0.44
UCEC	chrX	100833344	Nonsense_Mutation	novel	R458*	0.38
UCEC	chrX	100820422	Silent	rs750641957	A2A	0.37
UCEC	chrX	100833340	Silent	novel	E456E	0.3
UCEC	chrX	100838277	Missense_Mutation	novel	D550E	0.49
UCEC	chrX	100822261	Missense_Mutation	novel	D50N	0.46	RRM_1
UCEC	chrX	100830840	Intron	novel		0.45
UCEC	chrX	100821556	Nonsense_Mutation	novel	E30*	0.5	RRM_1
UCEC	chrX	100820395	5'Flank	novel		0.2
UCEC	chrX	100832878	Silent	novel	L392L	0.13
UCEC	chrX	100838280	Missense_Mutation	novel	Q551H	0.1
UCEC	chrX	100831602	Missense_Mutation	novel	P326L	0.16
UCEC	chrX	100822285	Missense_Mutation	novel	G58S	0.22	RRM_1
UCEC	chrX	100822353	Silent	rs144061026	R80R	0.41
UCEC	chrX	100831601	Missense_Mutation	novel	P326S	0.37
UCEC	chrX	100823326	Silent	novel	P114P	0.41
UCEC	chrX	100826752	Missense_Mutation	novel	P274H	0.07
UCEC	chrX	100826646	Missense_Mutation	novel	V239F	0.49
UCEC	chrX	100831564	Silent	rs148091932	A313A	0.08
UCEC	chrX	100823943	Missense_Mutation	NA	L168M	0.33
UCEC	chrX	100826734	Missense_Mutation	NA	G268D	0.39
UCEC	chrX	100833217	Missense_Mutation	novel	M415I	0.13
UCEC	chrX	100833248	Missense_Mutation	NA	D426Y	0.2
UCS	chrX	100824139	Missense_Mutation	novel	T195K	0.27
UCS	chrX	100833319	Silent	rs779142875	A449A	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	AMP	0.0265	0.12739
THCA	DEL	0.002	0.21991

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0051	Kaplan-Meier Survival Analysis
STAD	0.012	Kaplan-Meier Survival Analysis
SARC	0.0043	Kaplan-Meier Survival Analysis
MESO	0.015	Kaplan-Meier Survival Analysis
HNSC	0.0098	Kaplan-Meier Survival Analysis
BRCA	0.043	Kaplan-Meier Survival Analysis
ESCA	0.01	Kaplan-Meier Survival Analysis
TGCT	0.05	Kaplan-Meier Survival Analysis
PAAD	0.0097	Kaplan-Meier Survival Analysis
LAML	0.00023	Kaplan-Meier Survival Analysis
KICH	0.013	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
OV	0.0038	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000101811 (Gene tree)
Gene ID: 1478
Gene Symbol: CSTF2
Alias: CstF-64
Full Name: cleavage stimulation factor subunit 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 21,162 bases
Position: chrX:100,820,359-100,841,520
Accession: 2484
RBP type: canonical RBP
Summary: This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000362063	RRM_1	PF00076.22	6e-25	1	1
ENSP00000387996	RRM_1	PF00076.22	6.2e-25	1	1
ENSP00000415705	RRM_1	PF00076.22	2.4e-24	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
10606651	The Drosophila homologue of the 64 kDa subunit of cleavage stimulation factor interacts with the 77 kDa subunit encoded by the suppressor of forked gene.	Nucleic Acids Res	2000 Jan 15	Hatton LS	-
12773396	Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein.	EMBO J	2003 Jun 2	Perez Canadillas JM	-
15769465	Protein and RNA dynamics play key roles in determining the specific recognition of GU-rich polyadenylation regulatory elements by human Cstf-64 protein.	J Mol Biol	2005 Apr 8	Deka P	-
17029590	Polyadenylation proteins CstF-64 and tauCstF-64 exhibit differential binding affinities for RNA polymers.	Biochem J	2007 Feb 1	Monarez RR	-
16769980	Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription.	Genome Res	2006 Jul	Swinburne IA	-
9199325	RNA recognition by the human polyadenylation factor CstF.	Mol Cell Biol	1997 Jul	Takagaki Y	-
11241784	Elevated levels of the polyadenylation factor CstF 64 enhance formation of the 1kB Testis brain RNA-binding protein (TB-RBP) mRNA in male germ cells.	Mol Reprod Dev	2001 Apr	Chennathukuzhi VM	-
19887456	The hinge domain of the cleavage stimulation factor protein CstF-64 is essential for CstF-77 interaction, nuclear localization, and polyadenylation.	J Biol Chem	2010 Jan 1	Hockert JA	doi: 10.1074/jbc.M109.061705
18077340	Loss of polyadenylation protein tauCstF-64 causes spermatogenic defects and male infertility.	Proc Natl Acad Sci U S A	2007 Dec 18	Dass B	-
24149845	Overlapping and distinct functions of CstF64 and CstF64-tau in mammalian mRNA 3' processing.	RNA	2013 Dec	Yao C	doi: 10.1261/rna.042317.113
27812195	The Cstf2t Polyadenylation Gene Plays a Sex-Specific Role in Learning Behaviors in Mice.	PLoS One	2016 Nov 3	Harris JC	doi: 10.1371/journal.pone.0165976
24590791	High-throughput sequencing of RNA isolated by cross-linking and immunoprecipitation (HITS-CLIP) to determine sites of binding of CstF-64 on nascent RNAs.	Methods Mol Biol	2014	Grozdanov PN	doi: 10.1007/978-1-62703-971-0_17.
29673127	Cstf2t Regulates expression of histones and histone-like proteins in male germ cells.	Andrology	2018 Jul	Grozdanov PN	doi: 10.1111/andr.12488
30257008	The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity.	Nucleic Acids Res	2018 Dec 14	Grozdanov PN	doi: 10.1093/nar/gky862.
25258487	In silico characterization of a RNA binding protein of cattle filarial parasite Setaria digitata.	Bioinformation	2014 Aug 30	Nagaratnam N	doi: 10.6026/97320630010512

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000475126	CSTF2-204	1693	-	ENSP00000432060	438 (aa)	-	E9PID8
ENST00000413437	CSTF2-202	757	-	ENSP00000415705	225 (aa)	-	A0A0A0MT56
ENST00000415585	CSTF2-203	2074	-	ENSP00000387996	597 (aa)	-	E7EWR4
ENST00000372972	CSTF2-201	1958	-	ENSP00000362063	577 (aa)	-	P33240

Gene Model

Click here to download ENSG00000101811's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000101811's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000101811	CSTF2	84	88.360	ENSG00000177613	CSTF2T	99	69.255
ENSG00000101811	CSTF2	57	33.333	ENSG00000179950	PUF60	63	33.333

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000101811	CSTF2	95	83.178	ENSAPOG00000005630	cstf2	97	60.561	Acanthochromis_polyacanthus
ENSG00000101811	CSTF2	100	95.861	ENSAMEG00000002082	CSTF2	100	95.861	Ailuropoda_melanoleuca
ENSG00000101811	CSTF2	81	92.350	ENSACIG00000012852	cstf2	96	58.160	Amphilophus_citrinellus
ENSG00000101811	CSTF2	81	92.350	ENSAOCG00000020905	cstf2	97	60.513	Amphiprion_ocellaris
ENSG00000101811	CSTF2	81	92.350	ENSAPEG00000006526	cstf2	97	60.513	Amphiprion_percula
ENSG00000101811	CSTF2	79	93.820	ENSATEG00000018186	cstf2	97	57.541	Anabas_testudineus
ENSG00000101811	CSTF2	84	94.180	ENSAPLG00000007255	CSTF2	98	78.487	Anas_platyrhynchos
ENSG00000101811	CSTF2	100	98.614	ENSANAG00000022342	CSTF2	100	98.614	Aotus_nancymaae
ENSG00000101811	CSTF2	81	93.407	ENSACLG00000000779	cstf2	93	60.377	Astatotilapia_calliptera
ENSG00000101811	CSTF2	94	82.464	ENSAMXG00000021477	cstf2	96	98.413	Astyanax_mexicanus
ENSG00000101811	CSTF2	100	95.147	ENSBTAG00000003547	CSTF2	100	95.147	Bos_taurus
ENSG00000101811	CSTF2	100	98.995	ENSCJAG00000004422	CSTF2	100	98.995	Callithrix_jacchus
ENSG00000101811	CSTF2	100	96.360	ENSCAFG00000017551	CSTF2	100	96.360	Canis_familiaris
ENSG00000101811	CSTF2	100	96.482	ENSCAFG00020007619	CSTF2	100	96.482	Canis_lupus_dingo
ENSG00000101811	CSTF2	100	95.494	ENSCHIG00000016994	CSTF2	100	95.494	Capra_hircus
ENSG00000101811	CSTF2	100	98.325	ENSTSYG00000006529	CSTF2	100	98.325	Carlito_syrichta
ENSG00000101811	CSTF2	100	96.147	ENSCPOG00000015255	CSTF2	100	96.147	Cavia_porcellus
ENSG00000101811	CSTF2	100	98.995	ENSCCAG00000032975	CSTF2	100	98.995	Cebus_capucinus
ENSG00000101811	CSTF2	100	99.497	ENSCATG00000022835	CSTF2	100	99.497	Cercocebus_atys
ENSG00000101811	CSTF2	100	95.980	ENSCLAG00000001904	CSTF2	100	95.980	Chinchilla_lanigera
ENSG00000101811	CSTF2	100	99.665	ENSCSAG00000010360	CSTF2	100	99.665	Chlorocebus_sabaeus
ENSG00000101811	CSTF2	71	100.000	ENSCHOG00000012803	CSTF2	75	100.000	Choloepus_hoffmanni
ENSG00000101811	CSTF2	96	87.558	ENSCPBG00000014293	CSTF2	100	76.425	Chrysemys_picta_bellii
ENSG00000101811	CSTF2	100	99.665	ENSCANG00000030612	CSTF2	100	99.665	Colobus_angolensis_palliatus
ENSG00000101811	CSTF2	96	98.140	ENSCGRG00001023023	Cstf2	100	92.931	Cricetulus_griseus_chok1gshd
ENSG00000101811	CSTF2	96	98.140	ENSCGRG00000003897	Cstf2	100	89.828	Cricetulus_griseus_crigri
ENSG00000101811	CSTF2	83	91.398	ENSCVAG00000005731	cstf2	96	60.732	Cyprinodon_variegatus
ENSG00000101811	CSTF2	86	88.660	ENSDARG00000090788	cstf2	93	92.188	Danio_rerio
ENSG00000101811	CSTF2	100	92.746	ENSDORG00000007195	Cstf2	100	92.746	Dipodomys_ordii
ENSG00000101811	CSTF2	96	96.279	ENSETEG00000004931	CSTF2	68	93.243	Echinops_telfairi
ENSG00000101811	CSTF2	100	96.985	ENSEASG00005001216	CSTF2	100	96.985	Equus_asinus_asinus
ENSG00000101811	CSTF2	100	96.985	ENSECAG00000009325	CSTF2	100	96.985	Equus_caballus
ENSG00000101811	CSTF2	100	96.817	ENSFCAG00000007000	CSTF2	100	96.817	Felis_catus
ENSG00000101811	CSTF2	92	77.837	ENSFALG00000003859	CSTF2	100	78.014	Ficedula_albicollis
ENSG00000101811	CSTF2	100	96.360	ENSFDAG00000002416	CSTF2	100	96.360	Fukomys_damarensis
ENSG00000101811	CSTF2	82	90.811	ENSFHEG00000017065	cstf2	93	61.207	Fundulus_heteroclitus
ENSG00000101811	CSTF2	81	88.462	ENSGMOG00000005145	cstf2	99	56.799	Gadus_morhua
ENSG00000101811	CSTF2	100	79.181	ENSGALG00000006760	CSTF2	100	85.667	Gallus_gallus
ENSG00000101811	CSTF2	81	91.257	ENSGAFG00000020027	cstf2	96	59.520	Gambusia_affinis
ENSG00000101811	CSTF2	85	86.667	ENSGACG00000017326	cstf2	93	81.633	Gasterosteus_aculeatus
ENSG00000101811	CSTF2	100	78.628	ENSGAGG00000006037	CSTF2	100	78.515	Gopherus_agassizii
ENSG00000101811	CSTF2	100	100.000	ENSGGOG00000022267	CSTF2	100	100.000	Gorilla_gorilla
ENSG00000101811	CSTF2	81	93.407	ENSHBUG00000016183	cstf2	93	60.309	Haplochromis_burtoni
ENSG00000101811	CSTF2	100	82.322	ENSHGLG00000013455	-	100	82.322	Heterocephalus_glaber_female
ENSG00000101811	CSTF2	100	97.054	ENSHGLG00000000659	-	100	97.054	Heterocephalus_glaber_female
ENSG00000101811	CSTF2	100	82.496	ENSHGLG00100015391	-	100	82.496	Heterocephalus_glaber_male
ENSG00000101811	CSTF2	100	97.054	ENSHGLG00100001130	-	100	97.054	Heterocephalus_glaber_male
ENSG00000101811	CSTF2	93	82.629	ENSHCOG00000005157	cstf2	97	60.554	Hippocampus_comes
ENSG00000101811	CSTF2	80	91.713	ENSIPUG00000017839	cstf2	99	60.956	Ictalurus_punctatus
ENSG00000101811	CSTF2	100	96.187	ENSSTOG00000023445	CSTF2	100	96.187	Ictidomys_tridecemlineatus
ENSG00000101811	CSTF2	100	94.801	ENSJJAG00000020507	Cstf2	100	94.801	Jaculus_jaculus
ENSG00000101811	CSTF2	81	91.758	ENSKMAG00000001068	cstf2	96	59.722	Kryptolebias_marmoratus
ENSG00000101811	CSTF2	54	94.915	ENSLBEG00000028720	cstf2	87	89.062	Labrus_bergylta
ENSG00000101811	CSTF2	93	84.360	ENSLACG00000015927	CSTF2	99	67.805	Latimeria_chalumnae
ENSG00000101811	CSTF2	98	77.778	ENSLOCG00000015300	cstf2	93	64.505	Lepisosteus_oculatus
ENSG00000101811	CSTF2	96	97.674	ENSLAFG00000000474	CSTF2	100	92.295	Loxodonta_africana
ENSG00000101811	CSTF2	100	99.665	ENSMFAG00000043888	CSTF2	100	99.665	Macaca_fascicularis
ENSG00000101811	CSTF2	100	98.827	ENSMMUG00000013008	CSTF2	100	98.827	Macaca_mulatta
ENSG00000101811	CSTF2	100	99.665	ENSMNEG00000041824	CSTF2	100	99.665	Macaca_nemestrina
ENSG00000101811	CSTF2	100	99.665	ENSMLEG00000036870	CSTF2	100	99.665	Mandrillus_leucophaeus
ENSG00000101811	CSTF2	81	92.308	ENSMAMG00000020364	cstf2	96	58.834	Mastacembelus_armatus
ENSG00000101811	CSTF2	81	93.407	ENSMZEG00005007200	cstf2	96	60.377	Maylandia_zebra
ENSG00000101811	CSTF2	84	86.243	ENSMGAG00000004139	CSTF2	100	85.259	Meleagris_gallopavo
ENSG00000101811	CSTF2	96	98.140	ENSMAUG00000000965	Cstf2	100	93.276	Mesocricetus_auratus
ENSG00000101811	CSTF2	100	96.817	ENSMICG00000014121	CSTF2	100	96.817	Microcebus_murinus
ENSG00000101811	CSTF2	96	98.140	ENSMOCG00000008081	Cstf2	100	91.897	Microtus_ochrogaster
ENSG00000101811	CSTF2	84	92.308	ENSMMOG00000000538	cstf2	97	54.096	Mola_mola
ENSG00000101811	CSTF2	96	88.372	ENSMODG00000011785	CSTF2	100	82.178	Monodelphis_domestica
ENSG00000101811	CSTF2	96	98.140	MGP_CAROLIEiJ_G0033383	Cstf2	100	93.276	Mus_caroli
ENSG00000101811	CSTF2	96	98.140	ENSMUSG00000031256	Cstf2	100	93.276	Mus_musculus
ENSG00000101811	CSTF2	96	98.140	MGP_PahariEiJ_G0031923	Cstf2	100	93.437	Mus_pahari
ENSG00000101811	CSTF2	96	98.140	MGP_SPRETEiJ_G0034548	Cstf2	100	93.276	Mus_spretus
ENSG00000101811	CSTF2	96	98.605	ENSMPUG00000002339	CSTF2	100	91.111	Mustela_putorius_furo
ENSG00000101811	CSTF2	96	95.814	ENSMLUG00000004598	CSTF2	98	89.348	Myotis_lucifugus
ENSG00000101811	CSTF2	100	95.164	ENSNGAG00000021985	Cstf2	100	95.337	Nannospalax_galili
ENSG00000101811	CSTF2	80	92.265	ENSNBRG00000021694	cstf2	100	56.306	Neolamprologus_brichardi
ENSG00000101811	CSTF2	100	99.665	ENSNLEG00000007510	CSTF2	100	99.665	Nomascus_leucogenys
ENSG00000101811	CSTF2	91	79.848	ENSMEUG00000014025	-	100	81.369	Notamacropus_eugenii
ENSG00000101811	CSTF2	96	87.442	ENSMEUG00000007875	-	100	79.376	Notamacropus_eugenii
ENSG00000101811	CSTF2	96	88.837	ENSMEUG00000011186	-	100	84.055	Notamacropus_eugenii
ENSG00000101811	CSTF2	78	96.571	ENSOPRG00000003106	CSTF2	87	80.995	Ochotona_princeps
ENSG00000101811	CSTF2	100	95.494	ENSODEG00000002059	CSTF2	100	95.494	Octodon_degus
ENSG00000101811	CSTF2	81	92.857	ENSONIG00000002631	cstf2	99	57.477	Oreochromis_niloticus
ENSG00000101811	CSTF2	96	89.767	ENSOANG00000004208	CSTF2	87	90.000	Ornithorhynchus_anatinus
ENSG00000101811	CSTF2	100	95.321	ENSOCUG00000010468	CSTF2	100	95.321	Oryctolagus_cuniculus
ENSG00000101811	CSTF2	83	90.860	ENSORLG00000001380	cstf2	97	58.120	Oryzias_latipes
ENSG00000101811	CSTF2	83	90.860	ENSORLG00020021917	cstf2	97	58.462	Oryzias_latipes_hni
ENSG00000101811	CSTF2	83	90.860	ENSORLG00015011996	cstf2	97	58.120	Oryzias_latipes_hsok
ENSG00000101811	CSTF2	81	92.350	ENSOMEG00000015507	cstf2	97	59.966	Oryzias_melastigma
ENSG00000101811	CSTF2	96	98.605	ENSOGAG00000011192	CSTF2	100	90.143	Otolemur_garnettii
ENSG00000101811	CSTF2	100	95.494	ENSOARG00000001022	CSTF2	100	95.494	Ovis_aries
ENSG00000101811	CSTF2	100	100.000	ENSPPAG00000031804	CSTF2	100	100.000	Pan_paniscus
ENSG00000101811	CSTF2	100	96.985	ENSPPRG00000022492	CSTF2	100	96.985	Panthera_pardus
ENSG00000101811	CSTF2	100	96.650	ENSPTIG00000009922	CSTF2	100	96.650	Panthera_tigris_altaica
ENSG00000101811	CSTF2	100	100.000	ENSPTRG00000022090	CSTF2	100	100.000	Pan_troglodytes
ENSG00000101811	CSTF2	100	99.665	ENSPANG00000002303	CSTF2	100	99.665	Papio_anubis
ENSG00000101811	CSTF2	87	89.744	ENSPKIG00000005033	cstf2	97	61.073	Paramormyrops_kingsleyae
ENSG00000101811	CSTF2	81	92.308	ENSPMGG00000006534	cstf2	97	58.814	Periophthalmus_magnuspinnatus
ENSG00000101811	CSTF2	96	98.605	ENSPEMG00000019415	Cstf2	100	92.241	Peromyscus_maniculatus_bairdii
ENSG00000101811	CSTF2	96	88.837	ENSPCIG00000002989	CSTF2	100	82.759	Phascolarctos_cinereus
ENSG00000101811	CSTF2	81	91.803	ENSPLAG00000011176	cstf2	96	57.333	Poecilia_latipinna
ENSG00000101811	CSTF2	81	91.803	ENSPMEG00000017743	cstf2	96	57.167	Poecilia_mexicana
ENSG00000101811	CSTF2	81	91.803	ENSPREG00000011481	cstf2	97	60.272	Poecilia_reticulata
ENSG00000101811	CSTF2	100	99.832	ENSPPYG00000020541	CSTF2	100	99.832	Pongo_abelii
ENSG00000101811	CSTF2	100	97.822	ENSPCOG00000027744	CSTF2	100	97.822	Propithecus_coquereli
ENSG00000101811	CSTF2	97	80.790	ENSPVAG00000008342	CSTF2	100	80.790	Pteropus_vampyrus
ENSG00000101811	CSTF2	81	93.407	ENSPNYG00000010852	cstf2	94	91.781	Pundamilia_nyererei
ENSG00000101811	CSTF2	95	82.629	ENSPNAG00000018887	cstf2	97	61.873	Pygocentrus_nattereri
ENSG00000101811	CSTF2	96	98.140	ENSRNOG00000048025	Cstf2	100	92.759	Rattus_norvegicus
ENSG00000101811	CSTF2	100	97.920	ENSRBIG00000030745	CSTF2	100	97.920	Rhinopithecus_bieti
ENSG00000101811	CSTF2	100	99.665	ENSRROG00000045042	CSTF2	100	99.665	Rhinopithecus_roxellana
ENSG00000101811	CSTF2	100	98.995	ENSSBOG00000021649	CSTF2	100	98.995	Saimiri_boliviensis_boliviensis
ENSG00000101811	CSTF2	98	100.000	ENSSHAG00000003681	CSTF2	92	83.305	Sarcophilus_harrisii
ENSG00000101811	CSTF2	81	91.803	ENSSFOG00015006348	cstf2	98	63.471	Scleropages_formosus
ENSG00000101811	CSTF2	81	93.956	ENSSMAG00000013463	cstf2	97	59.354	Scophthalmus_maximus
ENSG00000101811	CSTF2	96	87.442	ENSSPUG00000005288	-	98	80.720	Sphenodon_punctatus
ENSG00000101811	CSTF2	100	95.645	ENSSSCG00000012486	CSTF2	100	96.970	Sus_scrofa
ENSG00000101811	CSTF2	100	79.422	ENSTGUG00000002253	CSTF2	100	79.592	Taeniopygia_guttata
ENSG00000101811	CSTF2	83	89.785	ENSTNIG00000016860	cstf2	99	59.593	Tetraodon_nigroviridis
ENSG00000101811	CSTF2	55	100.000	ENSTBEG00000010029	-	69	100.000	Tupaia_belangeri
ENSG00000101811	CSTF2	100	96.880	ENSTTRG00000013556	CSTF2	100	96.880	Tursiops_truncatus
ENSG00000101811	CSTF2	100	96.346	ENSUAMG00000026605	CSTF2	100	96.346	Ursus_americanus
ENSG00000101811	CSTF2	96	98.605	ENSUMAG00000012417	CSTF2	100	98.270	Ursus_maritimus
ENSG00000101811	CSTF2	95	98.598	ENSVPAG00000006466	CSTF2	72	96.210	Vicugna_pacos
ENSG00000101811	CSTF2	100	96.534	ENSVVUG00000004717	CSTF2	100	96.534	Vulpes_vulpes
ENSG00000101811	CSTF2	92	86.893	ENSXETG00000009642	cstf2	100	66.154	Xenopus_tropicalis
ENSG00000101811	CSTF2	75	94.675	ENSXCOG00000016436	cstf2	84	96.970	Xiphophorus_couchianus
ENSG00000101811	CSTF2	81	91.257	ENSXMAG00000013524	cstf2	97	56.070	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003723	RNA binding	1741396.	IDA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0005515	protein binding	10477523.11598190.14707147.16189514.18688255.19136632.20379136.25416956.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	21873635.	IBA	Component
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	18305108.21102410.	IDA	Component
GO:0006369	termination of RNA polymerase II transcription	-	TAS	Process
GO:0006378	mRNA polyadenylation	-	IEA	Process
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	-	TAS	Process
GO:0016604	nuclear body	-	IDA	Component
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0071920	cleavage body	11598190.	IDA	Component
GO:0098789	pre-mRNA cleavage required for polyadenylation	21873635.	IBA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

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Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.