EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19424630	Increased expression of telomere-related proteins correlates with resistance to radiation in human laryngeal cancer cell lines.	Oncol Rep	2009 Jun	Tang T	-
24260532	Telomere-binding protein TPP1 modulates telomere homeostasis and confers radioresistance to human colorectal cancer cells.	PLoS One	2013 Nov 19	Yang L	doi: 10.1371/journal.pone.0081034
28393830	Structural and functional analysis of the human POT1-TPP1 telomeric complex.	Nat Commun	2017 Apr 10	Rice C	doi: 10.1038/ncomms14928.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr16	67660463	Nonsense_Mutation	novel	Q6*	0.59
BLCA	chr16	67659692	Intron	novel		0.17
BLCA	chr16	67658011	Missense_Mutation	NA	G480E	0.23
BLCA	chr16	67660341	Silent	rs2303761	R46R	0.33
BLCA	chr16	67659365	Intron	novel		0.15
BLCA	chr16	67658330	Missense_Mutation	rs200298308	E374K	0.25
BLCA	chr16	67658567	Missense_Mutation	NA	P359T	0.17
BLCA	chr16	67660326	Silent	novel	L51L	0.4
BLCA	chr16	67658581	Missense_Mutation	novel	S354C	0.18
BLCA	chr16	67659232	Missense_Mutation	NA	A250T	0.95
BLCA	chr16	67659650	Intron	novel		0.04
BLCA	chr16	67659671	Intron	novel		0.1
BLCA	chr16	67658771	Missense_Mutation	novel	E317Q	0.38
BRCA	chr16	67660250	Missense_Mutation	NA	P77A	0.33
CESC	chr16	67658493	Intron	novel		0.21
CESC	chr16	67658243	Frame_Shift_Ins	novel	*P403Cfs38**	0.08
CESC	chr16	67658957	Missense_Mutation	NA	H292Y	0.44
CESC	chr16	67660529	5'UTR	novel		0.27
CESC	chr16	67658636	Missense_Mutation	NA	E336K	0.3
COAD	chr16	67659934	Missense_Mutation	NA	V157M	0.27	TPP1
COAD	chr16	67658041	Missense_Mutation	rs781117606	P470L	0.49
COAD	chr16	67659126	Intron	NA		0.37
COAD	chr16	67659626	Intron	novel		0.3
COAD	chr16	67658189	Missense_Mutation	rs762262197	R421C	0.39
COAD	chr16	67658045	Missense_Mutation	rs747913250	R469W	0.44
COAD	chr16	67660524	5'UTR	novel		0.54
COAD	chr16	67659430	Intron	novel		0.24
COAD	chr16	67659749	Silent	NA	L183L	0.27
COAD	chr16	67658233	Missense_Mutation	NA	C406Y	0.31
ESCA	chr16	67658693	Intron	novel		0.16
ESCA	chr16	67659262	Nonsense_Mutation	novel	E240*	0.15
ESCA	chr16	67659067	Missense_Mutation	novel	S255F	0.48
GBM	chr16	67659356	Intron	novel		0.41
GBM	chr16	67657679	Missense_Mutation	novel	P521L	0.41
GBM	chr16	67657585	3'UTR	novel		0.48
GBM	chr16	67657625	Missense_Mutation	novel	S539Y	0.32
GBM	chr16	67658899	Intron	novel		0.19
HNSC	chr16	67657840	Missense_Mutation	novel	R493M	0.29
HNSC	chr16	67659980	Silent	novel	G141G	0.5
HNSC	chr16	67657834	Missense_Mutation	rs374742891	R495H	0.22
HNSC	chr16	67660295	Missense_Mutation	novel	L62I	0.46
HNSC	chr16	67659557	Silent	novel	P217P	0.09
HNSC	chr16	67658796	Silent	rs374438854	V308V	0.15
KIRC	chr16	67658227	Missense_Mutation	NA	A408V	0.2
KIRC	chr16	67660365	Frame_Shift_Ins	novel	*R39Sfs81**	0.33
LGG	chr16	67658045	Missense_Mutation	rs747913250	R469W	0.56
LGG	chr16	67658209	Missense_Mutation	novel	P414H	0.49
LGG	chr16	67657587	3'UTR	novel		0.15
LUAD	chr16	67660379	Nonsense_Mutation	NA	R34*	0.55
LUAD	chr16	67659516	Intron	novel		0.11
LUAD	chr16	67659549	Missense_Mutation	novel	R220L	0.3
LUAD	chr16	67660349	Missense_Mutation	novel	G44C	0.31
LUAD	chr16	67658345	Missense_Mutation	novel	G369C	0.19
LUAD	chr16	67658488	Intron	novel		0.32
LUAD	chr16	67658043	Silent	NA	R469R	0.09
LUSC	chr16	67658713	Splice_Region	novel		0.22
LUSC	chr16	67660295	Missense_Mutation	NA	L62F	0.51
LUSC	chr16	67660185	Nonsense_Mutation	NA	W98*	0.18	TPP1
LUSC	chr16	67660188	Silent	NA	P97P	0.27
LUSC	chr16	67657766	Missense_Mutation	novel	V518L	0.26
LUSC	chr16	67659149	Intron	novel		0.38
OV	chr16	67657611	Missense_Mutation	novel	M544L	0.54
OV	chr16	67659288	Intron	novel		0.71
OV	chr16	67660196	Missense_Mutation	NA	L95V	0.12
OV	chr16	67659611	Splice_Region	novel	P199P	0.35
PAAD	chr16	67659346	Intron	novel		0.2
PRAD	chr16	67658906	Intron	novel		0.28
SARC	chr16	67657829	Missense_Mutation	novel	G497S	0.2
SKCM	chr16	67660326	Silent	NA	L51L	0.71
SKCM	chr16	67658203	Missense_Mutation	novel	S416F	0.31
SKCM	chr16	67660308	Silent	NA	A57A	0.54
SKCM	chr16	67660144	Missense_Mutation	NA	P112L	0.34	TPP1
SKCM	chr16	67659630	Intron	novel		0.38
SKCM	chr16	67658367	Splice_Region	novel		0.66
SKCM	chr16	67660349	Missense_Mutation	novel	G44S	0.29
SKCM	chr16	67660350	Silent	novel	R43R	0.27
SKCM	chr16	67660291	Missense_Mutation	NA	P63L	0.73
SKCM	chr16	67660295	Missense_Mutation	NA	L62F	0.9
SKCM	chr16	67660291	Missense_Mutation	NA	P63L	0.26
SKCM	chr16	67657603	3'UTR	rs372366640		0.18
SKCM	chr16	67660277	Missense_Mutation	NA	A68T	0.09
SKCM	chr16	67658652	Intron	novel		0.17
SKCM	chr16	67658579	Missense_Mutation	NA	P355T	0.23
SKCM	chr16	67660328	Missense_Mutation	NA	L51F	0.46
SKCM	chr16	67658155	Missense_Mutation	NA	P432L	0.27
SKCM	chr16	67659121	Intron	novel		0.11
SKCM	chr16	67660500	5'UTR	rs759315599		0.42
SKCM	chr16	67658980	Missense_Mutation	novel	P284L	0.33
SKCM	chr16	67659084	Splice_Region	novel		0.56
SKCM	chr16	67658916	Intron	novel		0.43
SKCM	chr16	67660298	Missense_Mutation	NA	P61S	0.38
SKCM	chr16	67660328	Missense_Mutation	NA	L51F	0.39
SKCM	chr16	67657797	Silent	novel	P507P	0.39
SKCM	chr16	67657798	Missense_Mutation	novel	P507L	0.39
SKCM	chr16	67659159	Intron	novel		0.51
SKCM	chr16	67660326	Silent	NA	L51L	0.33
SKCM	chr16	67658216	Silent	novel	L412L	0.26
SKCM	chr16	67659240	Missense_Mutation	rs149051014	S247L	0.53
SKCM	chr16	67660328	Missense_Mutation	NA	L51F	0.32
STAD	chr16	67657986	Missense_Mutation	NA	W488C	0.2
STAD	chr16	67658042	Missense_Mutation	rs746002676	P470S	0.17
STAD	chr16	67659350	Intron	novel		0.38
STAD	chr16	67659146	Intron	novel		0.38
STAD	chr16	67659479	Intron	novel		0.34
STAD	chr16	67659028	Missense_Mutation	NA	Q268R	0.21
STAD	chr16	67658759	Silent	novel	L321L	0.53
STAD	chr16	67658345	Missense_Mutation	NA	G369S	0.07
STAD	chr16	67660222	Missense_Mutation	NA	G86V	0.1
STAD	chr16	67658671	Intron	novel		0.29
STAD	chr16	67660258	Missense_Mutation	NA	N74S	0.15
THCA	chr16	67658956	Missense_Mutation	NA	H292R	0.18
UCEC	chr16	67658709	Intron	novel		0.5
UCEC	chr16	67658783	Missense_Mutation	novel	L313M	0.08
UCEC	chr16	67659725	Missense_Mutation	NA	V191I	0.2	TPP1
UCEC	chr16	67659017	Missense_Mutation	rs780989111	V272M	0.14
UCEC	chr16	67659263	Splice_Region	novel	E239E	0.33
UCEC	chr16	67659353	Intron	novel		0.44
UCEC	chr16	67658045	Missense_Mutation	rs747913250	R469W	0.49
UCEC	chr16	67660497	5'UTR	novel		0.47
UCEC	chr16	67660666	5'UTR	novel		0.6
UCEC	chr16	67658331	Silent	novel	S373S	0.11
UCEC	chr16	67657822	Missense_Mutation	novel	A499V	0.12
UCEC	chr16	67659047	Missense_Mutation	rs758515562	R262W	0.35
UCEC	chr16	67658753	Missense_Mutation	novel	L323M	0.35
UCEC	chr16	67658957	Frame_Shift_Del	NA	*H292Tfs30**	0.43
UCEC	chr16	67659163	Intron	novel		0.36
UCEC	chr16	67658485	Intron	novel		0.4
UCEC	chr16	67657619	Missense_Mutation	novel	P541L	0.48
UCEC	chr16	67657576	3'UTR	novel		0.39
UCEC	chr16	67658300	Missense_Mutation	NA	P384S	0.17
UCEC	chr16	67660544	5'UTR	novel		0.5
UCEC	chr16	67660325	Missense_Mutation	NA	L52I	0.22
UCEC	chr16	67657629	Missense_Mutation	NA	G538W	0.22
UCEC	chr16	67659273	Intron	novel		0.32
UCEC	chr16	67659547	Missense_Mutation	novel	V221L	0.43
UVM	chr16	67658966	Missense_Mutation	novel	P289A	0.47

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.1912	0.063591
CHOL	DEL	0.1667	0.23475
LAML	DEL	0.0314	0.0010312
TGCT	AMP	0.12	0.035574
UCEC	DEL	0.282	4.7164e-05

Survival Analysis

Cancer	P-value	Q-value
THYM	0.034	Kaplan-Meier Survival Analysis
KIRC	0.01	Kaplan-Meier Survival Analysis
MESO	0.03	Kaplan-Meier Survival Analysis
ACC	0.0093	Kaplan-Meier Survival Analysis
UCS	0.032	Kaplan-Meier Survival Analysis
HNSC	0.041	Kaplan-Meier Survival Analysis
LUSC	0.005	Kaplan-Meier Survival Analysis
PAAD	0.0042	Kaplan-Meier Survival Analysis
KICH	0.019	Kaplan-Meier Survival Analysis
UCEC	0.05	Kaplan-Meier Survival Analysis
LIHC	0.001	Kaplan-Meier Survival Analysis
DLBC	0.032	Kaplan-Meier Survival Analysis
LGG	0.0016	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000102977 (Gene tree)
Gene ID: 65057
Gene Symbol: ACD
Alias: Ptop|Pip1|Tpp1|Tint1
Full Name: ACD shelterin complex subunit and telomerase recruitment factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 3,304 bases
Position: chr16:67,657,512-67,660,815
Accession: 25070
RBP type: canonical RBP
Summary: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000377496	TPP1	PF10341.9	2.7e-23	1	1
ENSP00000478084	TPP1	PF10341.9	2.7e-23	1	1
ENSP00000483117	TPP1	PF10341.9	3.7e-23	1	1
ENSP00000473679	TPP1	PF10341.9	6e-21	1	1
ENSP00000219251	TPP1	PF10341.9	6.3e-21	1	1
ENSP00000497937	TPP1	PF10341.9	8.8e-21	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000602821	ACD-210	544	-	-	- (aa)	-	-
ENST00000647559	ACD-216	1626	-	ENSP00000497937	541 (aa)	-	UPI000013C776
ENST00000602423	ACD-205	386	-	-	- (aa)	-	-
ENST00000219251	ACD-201	2052	-	ENSP00000219251	455 (aa)	-	Q96AP0
ENST00000602519	ACD-206	997	-	-	- (aa)	-	-
ENST00000602945	ACD-213	805	-	-	- (aa)	-	-
ENST00000602656	ACD-208	714	-	-	- (aa)	-	-
ENST00000602382	ACD-204	662	-	ENSP00000473313	182 (aa)	-	R4GMR6
ENST00000602780	ACD-209	579	-	-	- (aa)	-	-
ENST00000620761	ACD-215	1476	-	ENSP00000478084	458 (aa)	-	A0A0C4DGT6
ENST00000620338	ACD-214	2065	XM_005256115	ENSP00000483117	544 (aa)	XP_005256172	Q96AP0
ENST00000602320	ACD-203	1408	-	ENSP00000473679	442 (aa)	-	R4GNJ5
ENST00000602850	ACD-211	883	-	ENSP00000473595	16 (aa)	-	R4GND4
ENST00000393919	ACD-202	1974	-	ENSP00000377496	458 (aa)	-	Q96AP0
ENST00000602622	ACD-207	2526	-	-	- (aa)	-	-
ENST00000602860	ACD-212	1858	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000102977's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000102977	Chemokine CCL2	4E-6	23251661

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000102977	rs7204371	16	67659894	A	Obesity-related traits	23251661	[NR] pg/mL increase	0.04	EFO_0004749

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000102977's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000102977	ACD	98	78.889	ENSAMEG00000017492	ACD	95	78.788	Ailuropoda_melanoleuca
ENSG00000102977	ACD	99	88.184	ENSANAG00000033228	ACD	99	82.528	Aotus_nancymaae
ENSG00000102977	ACD	100	71.834	ENSBTAG00000018903	ACD	100	64.622	Bos_taurus
ENSG00000102977	ACD	100	86.957	ENSCJAG00000016106	ACD	100	86.957	Callithrix_jacchus
ENSG00000102977	ACD	98	75.877	ENSCAFG00000020352	ACD	99	72.275	Canis_familiaris
ENSG00000102977	ACD	99	74.675	ENSCAFG00020018248	ACD	99	74.892	Canis_lupus_dingo
ENSG00000102977	ACD	100	69.414	ENSCHIG00000025516	ACD	100	69.631	Capra_hircus
ENSG00000102977	ACD	99	73.246	ENSTSYG00000036981	ACD	99	73.246	Carlito_syrichta
ENSG00000102977	ACD	98	65.854	ENSCPOG00000010719	ACD	99	65.967	Cavia_porcellus
ENSG00000102977	ACD	100	86.681	ENSCCAG00000023258	ACD	100	86.681	Cebus_capucinus
ENSG00000102977	ACD	99	65.275	ENSCLAG00000005336	ACD	91	65.227	Chinchilla_lanigera
ENSG00000102977	ACD	99	93.819	ENSCSAG00000003934	ACD	100	91.176	Chlorocebus_sabaeus
ENSG00000102977	ACD	100	93.668	ENSCANG00000031659	ACD	100	93.450	Colobus_angolensis_palliatus
ENSG00000102977	ACD	98	60.044	ENSCGRG00000011663	Acd	99	60.044	Cricetulus_griseus_crigri
ENSG00000102977	ACD	99	73.246	ENSDNOG00000001487	ACD	92	73.246	Dasypus_novemcinctus
ENSG00000102977	ACD	100	73.478	ENSEASG00005012855	ACD	100	72.650	Equus_asinus_asinus
ENSG00000102977	ACD	100	78.166	ENSECAG00000020293	ACD	100	78.166	Equus_caballus
ENSG00000102977	ACD	78	74.074	ENSEEUG00000001930	-	81	74.074	Erinaceus_europaeus
ENSG00000102977	ACD	99	78.947	ENSFCAG00000009280	ACD	99	79.167	Felis_catus
ENSG00000102977	ACD	99	63.596	ENSFDAG00000001447	ACD	99	56.371	Fukomys_damarensis
ENSG00000102977	ACD	100	98.253	ENSGGOG00000003881	ACD	100	98.253	Gorilla_gorilla
ENSG00000102977	ACD	99	67.105	ENSHGLG00000011190	ACD	99	67.105	Heterocephalus_glaber_female
ENSG00000102977	ACD	99	61.404	ENSHGLG00100013219	ACD	99	61.404	Heterocephalus_glaber_male
ENSG00000102977	ACD	97	67.265	ENSSTOG00000016455	ACD	87	67.265	Ictidomys_tridecemlineatus
ENSG00000102977	ACD	100	66.885	ENSJJAG00000010311	Acd	100	67.102	Jaculus_jaculus
ENSG00000102977	ACD	99	67.679	ENSLAFG00000007115	ACD	99	67.679	Loxodonta_africana
ENSG00000102977	ACD	100	94.323	ENSMFAG00000038023	ACD	100	94.105	Macaca_fascicularis
ENSG00000102977	ACD	100	94.541	ENSMMUG00000009805	ACD	100	94.323	Macaca_mulatta
ENSG00000102977	ACD	100	94.541	ENSMNEG00000031499	ACD	100	94.323	Macaca_nemestrina
ENSG00000102977	ACD	100	94.323	ENSMLEG00000028577	ACD	100	94.105	Mandrillus_leucophaeus
ENSG00000102977	ACD	98	56.733	ENSMAUG00000009516	Acd	99	56.733	Mesocricetus_auratus
ENSG00000102977	ACD	99	74.342	ENSMICG00000012170	ACD	99	75.000	Microcebus_murinus
ENSG00000102977	ACD	99	55.044	ENSMOCG00000019926	Acd	99	55.044	Microtus_ochrogaster
ENSG00000102977	ACD	98	37.872	ENSMODG00000005704	-	99	38.462	Monodelphis_domestica
ENSG00000102977	ACD	99	58.590	MGP_CAROLIEiJ_G0031490	Acd	99	59.424	Mus_caroli
ENSG00000102977	ACD	98	59.424	ENSMUSG00000038000	Acd	100	77.536	Mus_musculus
ENSG00000102977	ACD	98	60.268	MGP_PahariEiJ_G0023090	Acd	98	60.268	Mus_pahari
ENSG00000102977	ACD	98	59.424	MGP_SPRETEiJ_G0032608	Acd	99	59.424	Mus_spretus
ENSG00000102977	ACD	98	76.000	ENSMPUG00000006409	ACD	99	71.630	Mustela_putorius_furo
ENSG00000102977	ACD	99	73.696	ENSMLUG00000005251	ACD	99	69.941	Myotis_lucifugus
ENSG00000102977	ACD	98	62.472	ENSNGAG00000000950	Acd	99	62.472	Nannospalax_galili
ENSG00000102977	ACD	100	96.507	ENSNLEG00000035728	-	100	96.507	Nomascus_leucogenys
ENSG00000102977	ACD	58	46.324	ENSMEUG00000016071	-	95	47.720	Notamacropus_eugenii
ENSG00000102977	ACD	99	60.832	ENSOPRG00000013551	ACD	99	58.379	Ochotona_princeps
ENSG00000102977	ACD	99	62.661	ENSODEG00000015820	ACD	100	62.661	Octodon_degus
ENSG00000102977	ACD	99	64.114	ENSOCUG00000009011	ACD	99	64.114	Oryctolagus_cuniculus
ENSG00000102977	ACD	99	73.904	ENSOGAG00000033562	ACD	99	72.371	Otolemur_garnettii
ENSG00000102977	ACD	100	69.869	ENSOARG00000003098	ACD	100	66.796	Ovis_aries
ENSG00000102977	ACD	100	98.690	ENSPPAG00000023233	ACD	100	98.690	Pan_paniscus
ENSG00000102977	ACD	99	77.851	ENSPPRG00000001789	ACD	99	78.070	Panthera_pardus
ENSG00000102977	ACD	99	77.851	ENSPTIG00000017755	ACD	99	78.070	Panthera_tigris_altaica
ENSG00000102977	ACD	100	98.908	ENSPTRG00000008238	ACD	100	98.908	Pan_troglodytes
ENSG00000102977	ACD	100	94.760	ENSPANG00000017897	ACD	100	94.541	Papio_anubis
ENSG00000102977	ACD	98	60.265	ENSPEMG00000013098	Acd	99	60.044	Peromyscus_maniculatus_bairdii
ENSG00000102977	ACD	59	48.029	ENSPCIG00000017553	-	95	39.271	Phascolarctos_cinereus
ENSG00000102977	ACD	99	97.357	ENSPPYG00000007463	ACD	99	95.556	Pongo_abelii
ENSG00000102977	ACD	76	76.642	ENSPCAG00000009664	-	66	76.642	Procavia_capensis
ENSG00000102977	ACD	99	76.535	ENSPCOG00000027860	ACD	99	77.632	Propithecus_coquereli
ENSG00000102977	ACD	98	74.889	ENSPVAG00000016594	ACD	97	71.456	Pteropus_vampyrus
ENSG00000102977	ACD	98	60.976	ENSRNOG00000038973	Acd	99	60.976	Rattus_norvegicus
ENSG00000102977	ACD	99	90.989	ENSRBIG00000042682	ACD	100	86.287	Rhinopithecus_bieti
ENSG00000102977	ACD	100	93.886	ENSRROG00000006320	ACD	100	93.668	Rhinopithecus_roxellana
ENSG00000102977	ACD	100	85.371	ENSSBOG00000030006	ACD	100	85.590	Saimiri_boliviensis_boliviensis
ENSG00000102977	ACD	99	74.561	ENSSSCG00000029590	ACD	99	74.561	Sus_scrofa
ENSG00000102977	ACD	71	81.776	ENSTTRG00000009206	-	74	72.910	Tursiops_truncatus
ENSG00000102977	ACD	99	79.386	ENSUAMG00000015956	ACD	99	79.605	Ursus_americanus
ENSG00000102977	ACD	99	79.386	ENSUMAG00000019617	ACD	99	79.605	Ursus_maritimus
ENSG00000102977	ACD	88	74.390	ENSVVUG00000012482	ACD	99	74.257	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000723	telomere maintenance	15181449.	IDA	Process
GO:0000783	nuclear telomere cap complex	16880378.	IDA	Component
GO:0000784	nuclear chromosome, telomeric region	19135898.	HDA	Component
GO:0000784	nuclear chromosome, telomeric region	15380063.23685356.24270157.25172512.	IDA	Component
GO:0001501	skeletal system development	21873635.	IBA	Process
GO:0001655	urogenital system development	21873635.	IBA	Process
GO:0005515	protein binding	15181449.15231715.15380063.15383534.16189514.16880378.17237768.17632522.19648609.21044950.21829167.22101936.22763445.25172512.25416956.25910212.26496610.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006886	intracellular protein transport	15181449.	IMP	Process
GO:0016233	telomere capping	21873635.	IBA	Process
GO:0016233	telomere capping	25172512.	IDA	Process
GO:0016233	telomere capping	17632522.	IGI	Process
GO:0016233	telomere capping	17237767.	NAS	Process
GO:0016233	telomere capping	17237768.	TAS	Process
GO:0016604	nuclear body	21873635.	IBA	Component
GO:0016604	nuclear body	-	IDA	Component
GO:0030326	embryonic limb morphogenesis	21873635.	IBA	Process
GO:0031848	protection from non-homologous end joining at telomere	21873635.	IBA	Process
GO:0031848	protection from non-homologous end joining at telomere	18185984.	ISS	Process
GO:0032202	telomere assembly	21873635.	IBA	Process
GO:0032202	telomere assembly	16880378.	IMP	Process
GO:0032211	negative regulation of telomere maintenance via telomerase	15181449.	IGI	Process
GO:0032211	negative regulation of telomere maintenance via telomerase	15380063.	IMP	Process
GO:0032211	negative regulation of telomere maintenance via telomerase	17237768.25467444.	TAS	Process
GO:0032212	positive regulation of telomere maintenance via telomerase	21873635.	IBA	Process
GO:0032212	positive regulation of telomere maintenance via telomerase	17237768.	IDA	Process
GO:0035282	segmentation	21873635.	IBA	Process
GO:0042162	telomeric DNA binding	21873635.	IBA	Function
GO:0042162	telomeric DNA binding	23685356.	IDA	Function
GO:0044877	protein-containing complex binding	21873635.	IBA	Function
GO:0044877	protein-containing complex binding	25172512.	IPI	Function
GO:0051973	positive regulation of telomerase activity	21873635.	IBA	Process
GO:0051973	positive regulation of telomerase activity	17237768.	IDA	Process
GO:0060381	positive regulation of single-stranded telomeric DNA binding	21873635.	IBA	Process
GO:0060381	positive regulation of single-stranded telomeric DNA binding	17237767.	IDA	Process
GO:0070182	DNA polymerase binding	21873635.	IBA	Function
GO:0070182	DNA polymerase binding	17237767.25172512.	IPI	Function
GO:0070182	DNA polymerase binding	25467444.	TAS	Function
GO:0070187	shelterin complex	21873635.	IBA	Component
GO:0070187	shelterin complex	15383534.23685356.	IDA	Component
GO:0070187	shelterin complex	21852327.	IMP	Component
GO:0070187	shelterin complex	17237768.	TAS	Component
GO:0070198	protein localization to chromosome, telomeric region	21873635.	IBA	Process
GO:0070198	protein localization to chromosome, telomeric region	15181449.	IDA	Process
GO:0070198	protein localization to chromosome, telomeric region	15181449.	IMP	Process
GO:0070200	establishment of protein localization to telomere	25589350.	IMP	Process
GO:0070200	establishment of protein localization to telomere	25467444.	TAS	Process
GO:1902496	protein binding involved in negative regulation of telomere maintenance via telomerase	21873635.	IBA	Function
GO:1902990	mitotic telomere maintenance via semi-conservative replication	21873635.	IBA	Process
GO:1905324	telomere-telomerase complex assembly	21873635.	IBA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.