EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24452485	Correlation of low expression of hMOF with clinicopathological features of colorectal carcinoma, gastric cancer and renal cell carcinoma.	Int J Oncol	2014 Apr	Cao L	doi: 10.3892/ijo.2014.2266
22152480	FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1.	Mol Cell	2011 Dec 9	Katoh H	doi: 10.1016/j.molcel.2011.10.012.
27292636	MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.	Cell Rep	2016 Jun 21	Luo H	doi: 10.1016/j.celrep.2016.05.050
25873202	Expression of hMOF, but not HDAC4, is responsible for the global histone H4K16 acetylation in gastric carcinoma.	Int J Oncol	2015	Zhu L	doi: 10.3892/ijo.2015.2956
25483274	Expression of hMOF in different ovarian tissues and its effects on ovarian cancer prognosis.	Oncol Rep	2015 Feb	Cai M	doi: 10.3892/or.2014.3649
24702180	Coactivator MYST1 regulates nuclear factor-??B and androgen receptor functions during proliferation of prostate cancer cells.	Mol Endocrinol	2014 Jun	Jaganathan A	doi: 10.1210/me.2014-1055
23638218	RNAi screening identifies KAT8 as a key molecule important for cancer cell survival.	Int J Clin Exp Pathol	2013 Apr 15	Zhang S	-
24571482	The histone acetylranseferase hMOF acetylates Nrf2 and regulates anti-drug responses in human non-small cell lung cancer.	Br J Pharmacol	2014 Jul	Chen Z	doi: 10.1111/bph.12661.
27268279	KAT8 Regulates Androgen Signaling in Prostate Cancer Cells.	Mol Endocrinol	2016 Aug	Kim JY	doi: 10.1210/me.2016-1024

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr16	31130526	Silent	NA	L359L	0.36
BLCA	chr16	31120471	Missense_Mutation	NA	R140H	0.39
BLCA	chr16	31120344	Missense_Mutation	NA	R98W	0.23	Tudor-knot
BLCA	chr16	31120356	Missense_Mutation	novel	E102K	0.5	Tudor-knot
BLCA	chr16	31120470	Missense_Mutation	NA	R140C	0.39
BLCA	chr16	31127198	Missense_Mutation	novel	V176M	0.11
BLCA	chr16	31120249	Missense_Mutation	novel	H92P	0.11	Tudor-knot
BLCA	chr16	31131144	Intron	novel		0.5
BRCA	chr16	31127087	Missense_Mutation	novel	A172V	0.23
BRCA	chr16	31130268	In_Frame_Del	NA	K306del	0.36
BRCA	chr16	31117662	5'Flank	rs758505941		0.37
BRCA	chr16	31120228	Missense_Mutation	NA	G85D	0.13	Tudor-knot
BRCA	chr16	31130468	Missense_Mutation	NA	S340F	0.32
CESC	chr16	31120455	Missense_Mutation	novel	E135K	0.56
CESC	chr16	31131281	3'UTR	novel		0.36
CESC	chr16	31130113	Missense_Mutation	NA	E290Q	0.17
CESC	chr16	31130742	Splice_Region	novel		0.29
COAD	chr16	31120502	Silent	novel	N150N	0.19
COAD	chr16	31130786	Missense_Mutation	novel	L400M	0.27
COAD	chr16	31130668	Intron	novel		0.71
COAD	chr16	31117831	Silent	NA	E50E	0.49
COAD	chr16	31131344	3'UTR	novel		0.25
COAD	chr16	31120377	Silent	NA	L109L	0.11
COAD	chr16	31130058	Silent	novel	L271L	0.05
COAD	chr16	31130060	Missense_Mutation	novel	D272V	0.05
COAD	chr16	31128070	Frame_Shift_Ins	rs773168027	*G237Rfs16**	0.25
COAD	chr16	31130315	Frame_Shift_Del	NA	*Y323Tfs48**	0.44
COAD	chr16	31130820	Missense_Mutation	novel	G411D	0.19
COAD	chr16	31127059	Missense_Mutation	rs747070698	T163A	0.3
COAD	chr16	31130907	Splice_Region	novel		0.17
ESCA	chr16	31120405	Missense_Mutation	novel	A118V	0.13
ESCA	chr16	31117691	Missense_Mutation	novel	Q4E	0.11
ESCA	chr16	31131301	3'UTR	novel		0.29
GBM	chr16	31127343	Missense_Mutation	NA	R224H	0.31
GBM	chr16	31130758	Missense_Mutation	novel	S390R	0.17
GBM	chr16	31130067	Missense_Mutation	novel	K274N	0.42
GBM	chr16	31127206	Silent	novel	Y178Y	0.32
HNSC	chr16	31127077	Missense_Mutation	novel	E169K	0.22
HNSC	chr16	31120395	Missense_Mutation	novel	V115L	0.37
HNSC	chr16	31127027	Splice_Region	novel		0.16
KIRC	chr16	31131271	3'UTR	rs760716648		0.16
KIRC	chr16	31130487	Silent	rs757723541	V346V	0.14
KIRP	chr16	31120243	Missense_Mutation	NA	Y90C	0.43	Tudor-knot
LGG	chr16	31120345	Missense_Mutation	rs748699921	R98Q	0.38	Tudor-knot
LGG	chr16	31130338	Silent	rs748985603	Y328Y	0.27
LIHC	chr16	31130840	Missense_Mutation	novel	T418S	0.13
LUAD	chr16	31131079	Intron	novel		0.27
LUAD	chr16	31130101	Missense_Mutation	novel	Y286H	0.07
LUAD	chr16	31127254	Silent	novel	F194F	0.08
LUAD	chr16	31130833	Silent	novel	I415I	0.07
LUAD	chr16	31127029	Splice_Region	novel		0.26
LUAD	chr16	31130819	Missense_Mutation	novel	G411S	0.36
LUAD	chr16	31127273	Missense_Mutation	novel	Y201N	0.28
LUSC	chr16	31130664	Intron	novel		0.13
LUSC	chr16	31131286	3'UTR	novel		0.52
LUSC	chr16	31120233	Missense_Mutation	NA	E87Q	0.03	Tudor-knot
LUSC	chr16	31131203	Missense_Mutation	NA	V441L	0.25
LUSC	chr16	31130267	Nonsense_Mutation	NA	E305*	0.37
LUSC	chr16	31120374	Missense_Mutation	NA	R108W	0.24	Tudor-knot
LUSC	chr16	31120377	Silent	NA	L109L	0.29
LUSC	chr16	31130292	Missense_Mutation	novel	N313S	0.38
LUSC	chr16	31120513	Missense_Mutation	novel	K154R	0.32
MESO	chr16	31131304	3'UTR	novel		0.22
OV	chr16	31126932	Intron	novel		0.15
OV	chr16	31120230	Missense_Mutation	NA	R86G	0.46	Tudor-knot
OV	chr16	31120340	Missense_Mutation	NA	F96L	0.21	Tudor-knot
OV	chr16	31131220	Frame_Shift_Ins	novel	*K449Qfs39**	0.19
OV	chr16	31130638	Intron	novel		0.18
READ	chr16	31120344	Missense_Mutation	NA	R98W	0.4	Tudor-knot
SKCM	chr16	31130497	Missense_Mutation	NA	E350K	0.15
SKCM	chr16	31130267	Missense_Mutation	novel	E305K	0.29
SKCM	chr16	31130497	Missense_Mutation	NA	E350K	0.24
SKCM	chr16	31131202	Silent	novel	S440S	0.21
SKCM	chr16	31130700	Intron	novel		0.58
SKCM	chr16	31130146	Missense_Mutation	NA	Y301H	0.16
SKCM	chr16	31130089	Missense_Mutation	NA	P282S	0.18
SKCM	chr16	31120344	Missense_Mutation	NA	R98W	0.24	Tudor-knot
SKCM	chr16	31130592	Silent	NA	S381S	0.15
SKCM	chr16	31130488	Missense_Mutation	NA	G347S	0.61
STAD	chr16	31130612	Splice_Region	novel		0.23
STAD	chr16	31120483	Missense_Mutation	NA	R144H	0.39
STAD	chr16	31120343	Missense_Mutation	novel	N97K	0.08	Tudor-knot
STAD	chr16	31117849	Missense_Mutation	NA	E56D	0.57	Tudor-knot
STAD	chr16	31120470	Missense_Mutation	novel	R140G	0.48
STAD	chr16	31131221	Frame_Shift_Del	NA	*K449Sfs20**	0.26
STAD	chr16	31128071	Frame_Shift_Del	NA	*E239Rfs50**	0.33
STAD	chr16	31127226	Missense_Mutation	NA	G185E	0.37
STAD	chr16	31128071	Frame_Shift_Del	NA	*E239Rfs50**	0.3
STAD	chr16	31130860	Silent	NA	E424E	0.33
STAD	chr16	31120458	Missense_Mutation	NA	R136C	0.19
STAD	chr16	31120482	Missense_Mutation	NA	R144C	0.34
STAD	chr16	31127343	Missense_Mutation	NA	R224H	0.14
STAD	chr16	31120458	Missense_Mutation	NA	R136C	0.2
STAD	chr16	31120471	Missense_Mutation	NA	R140H	0.27
STAD	chr16	31127234	Missense_Mutation	NA	E188K	0.25
STAD	chr16	31126939	Intron	novel		0.32
STAD	chr16	31120344	Missense_Mutation	NA	R98W	0.26	Tudor-knot
STAD	chr16	31120344	Missense_Mutation	NA	R98W	0.13	Tudor-knot
TGCT	chr16	31117696	Silent	novel	G5G	0.27
THCA	chr16	31130575	Missense_Mutation	NA	F376L	0.29
UCEC	chr16	31131338	3'UTR	novel		0.33
UCEC	chr16	31127195	Missense_Mutation	novel	K175E	0.4
UCEC	chr16	31130315	Frame_Shift_Del	NA	*Y323Tfs48**	0.16
UCEC	chr16	31127279	Missense_Mutation	NA	K203E	0.48
UCEC	chr16	31130057	Missense_Mutation	NA	L271Q	0.43
UCEC	chr16	31120374	Missense_Mutation	NA	R108W	0.51	Tudor-knot
UCEC	chr16	31130806	Silent	novel	V406V	0.16
UCEC	chr16	31131139	Intron	novel		0.11
UCEC	chr16	31127270	Missense_Mutation	NA	D200N	0.23
UCEC	chr16	31120424	Silent	novel	E124E	0.26
UCEC	chr16	31127234	Missense_Mutation	NA	E188K	0.56
UCEC	chr16	31127325	Missense_Mutation	novel	K218I	0.55
UCEC	chr16	31120415	Missense_Mutation	novel	K121N	0.47
UCEC	chr16	31127079	Missense_Mutation	NA	E169D	0.34
UCEC	chr16	31127234	Missense_Mutation	NA	E188K	0.11
UCEC	chr16	31131331	3'UTR	novel		0.35
UCEC	chr16	31128116	Missense_Mutation	rs750420411	E250K	0.4
UCEC	chr16	31127343	Missense_Mutation	NA	R224H	0.36
UCEC	chr16	31130886	Missense_Mutation	novel	K433R	0.31
UCEC	chr16	31120470	Missense_Mutation	NA	R140C	0.38
UCEC	chr16	31120346	Silent	novel	R98R	0.26
UCEC	chr16	31128121	Silent	novel	V251V	0.59
UCEC	chr16	31130268	In_Frame_Del	NA	K306del	0.27
UCEC	chr16	31131182	Intron	novel		0.19

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.0556	0.23475
LUAD	AMP	0.2481	0.20955

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.012	Kaplan-Meier Survival Analysis
MESO	0.0031	Kaplan-Meier Survival Analysis
COAD	0.046	Kaplan-Meier Survival Analysis
CESC	0.024	Kaplan-Meier Survival Analysis
LAML	0.015	Kaplan-Meier Survival Analysis
KICH	0.035	Kaplan-Meier Survival Analysis
LGG	0.031	Kaplan-Meier Survival Analysis
LUAD	0.0025	Kaplan-Meier Survival Analysis
UVM	0.00017	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000103510 (Gene tree)
Gene ID: 84148
Gene Symbol: KAT8
Alias: MOF|FLJ14040|hMOF|ZC2HC8|MYST1
Full Name: lysine acetyltransferase 8
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 15,640 bases
Position: chr16:31,115,754-31,131,393
Accession: 17933
RBP type: canonical RBP
Summary: This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000219797	Tudor-knot	PF11717.8	3.9e-21	1	1
ENSP00000456933	Tudor-knot	PF11717.8	3.9e-21	1	1
ENSP00000406037	Tudor-knot	PF11717.8	4e-21	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
15964847	Structure of the chromo barrel domain from the MOF acetyltransferase.	J Biol Chem	2005 Sep 16	Nielsen PR	-
19578370	Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing.	Nat Cell Biol	2009 Aug	Zhou Y	doi: 10.1038/ncb1914
10839822	Acetylation of histones and transcription-related factors.	Microbiol Mol Biol Rev	2000 Jun	Sterner DE	-
29929416	MoSnt2-dependent deacetylation of histone H3 mediates MoTor-dependent autophagy and plant infection by the rice blast fungus Magnaporthe oryzae.	Autophagy	2018	He M	doi: 10.1080/15548627.2018.1458171

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000539683	KAT8-205	1051	-	-	- (aa)	-	-
ENST00000543774	KAT8-206	1846	-	ENSP00000456933	458 (aa)	-	Q9H7Z6
ENST00000537402	KAT8-203	1345	-	ENSP00000454592	187 (aa)	-	H3BMX5
ENST00000538768	KAT8-204	2500	-	-	- (aa)	-	-
ENST00000448516	KAT8-202	1789	-	ENSP00000406037	467 (aa)	-	Q9H7Z6
ENST00000573144	KAT8-207	610	-	-	- (aa)	-	-
ENST00000219797	KAT8-201	1525	XM_011545970	ENSP00000219797	458 (aa)	XP_011544272	Q9H7Z6

Gene Model

Click here to download ENSG00000103510's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000103510	Body Mass Index	2E-6	25673413
ENSG00000103510	Body Mass Index	9E-11	25673413
ENSG00000103510	Body Mass Index	8E-10	25673413
ENSG00000103510	Waist Circumference	7E-9	25673412

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000103510	rs1549293	16	31130672	T	Waist circumference	25673412	[0.013-0.027] unit decrease	0.0201	EFO_0004342
ENSG00000103510	rs9925964	16	31118574	A	BMI (adjusted for smoking behaviour)	28443625	[0.012-0.025] kg/m2 increase	0.0185	EFO_0004318\|EFO_0004340
ENSG00000103510	rs9925964	16	31118574	A	Body mass index (joint analysis main effects and smoking interaction)	28443625			EFO_0004318\|EFO_0004340
ENSG00000103510	rs9925964	16	31118574	A	BMI in non-smokers	28443625	[0.011-0.026] kg/m2 increase	0.0183	EFO_0004340
ENSG00000103510	rs9925964	16	31118574	A	Body mass index	26426971	unit increase	0.019869572	EFO_0004340
ENSG00000103510	rs9925964	16	31118574	A	Body mass index	30108127	[NR] unit increase	0.019	EFO_0004340
ENSG00000103510	rs59735493	16	31121779	A	Worry	29942085	[0.0097-0.0201] unit decrease	0.01492	EFO_0005230
ENSG00000103510	rs59735493	16	31121779	A	Family history of Alzheimer's disease	30617256	NR z-score decrease	4.627	EFO_0009268
ENSG00000103510	rs59735493	16	31121779	A	Alzheimer's disease or family history of Alzheimer's disease	30617256	NR z-unit decrease	5.49	EFO_0000249\|EFO_0009268

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000103510's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000103510	KAT8	99	93.514	ENSAPOG00000008390	kat8	91	83.964	Acanthochromis_polyacanthus
ENSG00000103510	KAT8	99	98.919	ENSAMEG00000007229	KAT8	100	98.383	Ailuropoda_melanoleuca
ENSG00000103510	KAT8	99	91.979	ENSACIG00000023369	kat8	96	83.077	Amphilophus_citrinellus
ENSG00000103510	KAT8	99	93.514	ENSAOCG00000016764	kat8	90	85.586	Amphiprion_ocellaris
ENSG00000103510	KAT8	99	93.514	ENSAPEG00000006637	kat8	90	85.586	Amphiprion_percula
ENSG00000103510	KAT8	99	94.054	ENSATEG00000019285	kat8	92	83.885	Anabas_testudineus
ENSG00000103510	KAT8	99	96.757	ENSACAG00000006708	KAT8	96	87.061	Anolis_carolinensis
ENSG00000103510	KAT8	99	99.462	ENSANAG00000024175	KAT8	100	96.603	Aotus_nancymaae
ENSG00000103510	KAT8	99	93.514	ENSACLG00000018964	kat8	91	83.850	Astatotilapia_calliptera
ENSG00000103510	KAT8	99	94.054	ENSAMXG00000009619	kat8	87	85.491	Astyanax_mexicanus
ENSG00000103510	KAT8	100	99.345	ENSBTAG00000010511	KAT8	100	99.345	Bos_taurus
ENSG00000103510	KAT8	92	60.465	WBGene00010537	mys-2	74	45.478	Caenorhabditis_elegans
ENSG00000103510	KAT8	100	99.127	ENSCJAG00000003122	KAT8	100	99.127	Callithrix_jacchus
ENSG00000103510	KAT8	100	98.472	ENSCAFG00000016838	KAT8	100	98.472	Canis_familiaris
ENSG00000103510	KAT8	100	99.127	ENSCAFG00020018164	KAT8	97	99.127	Canis_lupus_dingo
ENSG00000103510	KAT8	100	99.127	ENSCHIG00000018433	KAT8	100	99.127	Capra_hircus
ENSG00000103510	KAT8	99	100.000	ENSTSYG00000035587	KAT8	100	95.378	Carlito_syrichta
ENSG00000103510	KAT8	99	70.811	ENSCAPG00000015928	KAT8	100	83.333	Cavia_aperea
ENSG00000103510	KAT8	100	99.127	ENSCPOG00000001000	KAT8	100	99.127	Cavia_porcellus
ENSG00000103510	KAT8	100	99.127	ENSCCAG00000026625	KAT8	100	99.127	Cebus_capucinus
ENSG00000103510	KAT8	100	99.782	ENSCATG00000043167	KAT8	100	99.782	Cercocebus_atys
ENSG00000103510	KAT8	100	99.127	ENSCLAG00000016958	KAT8	100	99.127	Chinchilla_lanigera
ENSG00000103510	KAT8	100	99.782	ENSCSAG00000005731	KAT8	100	99.782	Chlorocebus_sabaeus
ENSG00000103510	KAT8	92	98.837	ENSCHOG00000009927	KAT8	99	84.053	Choloepus_hoffmanni
ENSG00000103510	KAT8	99	98.378	ENSCPBG00000013186	KAT8	98	89.310	Chrysemys_picta_bellii
ENSG00000103510	KAT8	99	84.865	ENSCING00000021695	-	97	70.070	Ciona_intestinalis
ENSG00000103510	KAT8	99	100.000	ENSCANG00000038985	KAT8	97	90.787	Colobus_angolensis_palliatus
ENSG00000103510	KAT8	99	100.000	ENSCGRG00001018364	Kat8	100	98.472	Cricetulus_griseus_chok1gshd
ENSG00000103510	KAT8	99	100.000	ENSCGRG00000013034	Kat8	100	98.035	Cricetulus_griseus_crigri
ENSG00000103510	KAT8	99	91.892	ENSCSEG00000008855	kat8	95	83.814	Cynoglossus_semilaevis
ENSG00000103510	KAT8	99	93.514	ENSCVAG00000014961	kat8	92	84.106	Cyprinodon_variegatus
ENSG00000103510	KAT8	99	95.135	ENSDARG00000027187	kat8	89	85.491	Danio_rerio
ENSG00000103510	KAT8	100	99.127	ENSDNOG00000035332	KAT8	97	99.127	Dasypus_novemcinctus
ENSG00000103510	KAT8	93	67.241	FBgn0014340	mof	52	54.292	Drosophila_melanogaster
ENSG00000103510	KAT8	99	85.405	ENSEBUG00000016335	kat8	91	83.777	Eptatretus_burgeri
ENSG00000103510	KAT8	99	100.000	ENSEASG00005011119	KAT8	100	98.475	Equus_asinus_asinus
ENSG00000103510	KAT8	99	100.000	ENSECAG00000018567	KAT8	100	98.475	Equus_caballus
ENSG00000103510	KAT8	84	99.367	ENSEEUG00000002750	KAT8	81	99.145	Erinaceus_europaeus
ENSG00000103510	KAT8	99	95.676	ENSELUG00000023184	kat8	97	86.130	Esox_lucius
ENSG00000103510	KAT8	100	98.908	ENSFCAG00000002605	KAT8	100	98.908	Felis_catus
ENSG00000103510	KAT8	99	100.000	ENSFDAG00000012965	KAT8	100	98.690	Fukomys_damarensis
ENSG00000103510	KAT8	56	89.423	ENSFHEG00000022224	kat8	92	76.206	Fundulus_heteroclitus
ENSG00000103510	KAT8	99	85.946	ENSGMOG00000015257	kat8	92	78.289	Gadus_morhua
ENSG00000103510	KAT8	99	91.892	ENSGAFG00000019342	kat8	93	83.180	Gambusia_affinis
ENSG00000103510	KAT8	99	92.432	ENSGACG00000014930	kat8	83	90.244	Gasterosteus_aculeatus
ENSG00000103510	KAT8	99	97.838	ENSGAGG00000017021	KAT8	98	88.692	Gopherus_agassizii
ENSG00000103510	KAT8	100	99.143	ENSGGOG00000013606	KAT8	100	99.143	Gorilla_gorilla
ENSG00000103510	KAT8	99	93.514	ENSHBUG00000000951	kat8	91	83.407	Haplochromis_burtoni
ENSG00000103510	KAT8	99	100.000	ENSHGLG00000016838	KAT8	100	98.690	Heterocephalus_glaber_female
ENSG00000103510	KAT8	99	100.000	ENSHGLG00100007085	KAT8	100	100.000	Heterocephalus_glaber_male
ENSG00000103510	KAT8	99	92.432	ENSHCOG00000006613	kat8	95	83.407	Hippocampus_comes
ENSG00000103510	KAT8	99	94.595	ENSIPUG00000007291	KAT8	89	85.011	Ictalurus_punctatus
ENSG00000103510	KAT8	100	98.908	ENSSTOG00000000636	KAT8	100	98.908	Ictidomys_tridecemlineatus
ENSG00000103510	KAT8	99	100.000	ENSJJAG00000016363	Kat8	100	98.253	Jaculus_jaculus
ENSG00000103510	KAT8	99	92.973	ENSKMAG00000003370	kat8	96	80.667	Kryptolebias_marmoratus
ENSG00000103510	KAT8	99	92.973	ENSLBEG00000007401	kat8	91	84.071	Labrus_bergylta
ENSG00000103510	KAT8	83	85.897	ENSLACG00000005310	KAT8	90	76.351	Latimeria_chalumnae
ENSG00000103510	KAT8	96	87.723	ENSLAFG00000014059	KAT8	97	87.859	Loxodonta_africana
ENSG00000103510	KAT8	100	99.782	ENSMFAG00000030391	KAT8	100	99.782	Macaca_fascicularis
ENSG00000103510	KAT8	100	99.782	ENSMMUG00000002030	KAT8	100	99.782	Macaca_mulatta
ENSG00000103510	KAT8	100	99.782	ENSMNEG00000043883	KAT8	100	98.504	Macaca_nemestrina
ENSG00000103510	KAT8	99	100.000	ENSMLEG00000027653	KAT8	100	99.242	Mandrillus_leucophaeus
ENSG00000103510	KAT8	99	92.973	ENSMAMG00000019293	kat8	95	83.223	Mastacembelus_armatus
ENSG00000103510	KAT8	99	93.514	ENSMZEG00005013966	-	100	90.571	Maylandia_zebra
ENSG00000103510	KAT8	99	93.514	ENSMZEG00005002275	kat8	91	83.850	Maylandia_zebra
ENSG00000103510	KAT8	99	100.000	ENSMAUG00000009112	Kat8	100	98.472	Mesocricetus_auratus
ENSG00000103510	KAT8	100	99.127	ENSMICG00000001625	KAT8	100	99.127	Microcebus_murinus
ENSG00000103510	KAT8	99	100.000	ENSMOCG00000011257	Kat8	100	98.035	Microtus_ochrogaster
ENSG00000103510	KAT8	99	92.432	ENSMMOG00000020150	kat8	96	83.223	Mola_mola
ENSG00000103510	KAT8	99	98.919	ENSMODG00000001856	KAT8	100	99.267	Monodelphis_domestica
ENSG00000103510	KAT8	99	93.514	ENSMALG00000014639	kat8	96	84.257	Monopterus_albus
ENSG00000103510	KAT8	99	99.459	MGP_CAROLIEiJ_G0030530	Kat8	100	98.253	Mus_caroli
ENSG00000103510	KAT8	99	99.459	ENSMUSG00000030801	Kat8	100	98.253	Mus_musculus
ENSG00000103510	KAT8	99	99.459	MGP_PahariEiJ_G0013737	Kat8	100	98.253	Mus_pahari
ENSG00000103510	KAT8	99	99.459	MGP_SPRETEiJ_G0031644	Kat8	100	98.253	Mus_spretus
ENSG00000103510	KAT8	96	91.236	ENSMPUG00000011488	KAT8	97	91.333	Mustela_putorius_furo
ENSG00000103510	KAT8	99	100.000	ENSMLUG00000004779	KAT8	100	98.690	Myotis_lucifugus
ENSG00000103510	KAT8	99	100.000	ENSNGAG00000011761	Kat8	100	97.380	Nannospalax_galili
ENSG00000103510	KAT8	99	93.514	ENSNBRG00000008981	kat8	97	83.407	Neolamprologus_brichardi
ENSG00000103510	KAT8	100	98.908	ENSNLEG00000016179	KAT8	100	98.908	Nomascus_leucogenys
ENSG00000103510	KAT8	99	98.919	ENSMEUG00000014332	KAT8	100	99.225	Notamacropus_eugenii
ENSG00000103510	KAT8	97	81.573	ENSOPRG00000010764	KAT8	97	81.573	Ochotona_princeps
ENSG00000103510	KAT8	100	99.127	ENSODEG00000014799	KAT8	100	99.127	Octodon_degus
ENSG00000103510	KAT8	99	93.514	ENSONIG00000009451	kat8	93	84.071	Oreochromis_niloticus
ENSG00000103510	KAT8	100	99.127	ENSOCUG00000002300	KAT8	100	99.127	Oryctolagus_cuniculus
ENSG00000103510	KAT8	99	92.973	ENSORLG00000001137	kat8	92	83.444	Oryzias_latipes
ENSG00000103510	KAT8	99	92.973	ENSORLG00020017132	kat8	92	83.444	Oryzias_latipes_hni
ENSG00000103510	KAT8	99	92.973	ENSORLG00015008231	kat8	92	83.664	Oryzias_latipes_hsok
ENSG00000103510	KAT8	99	94.054	ENSOMEG00000015927	kat8	90	85.202	Oryzias_melastigma
ENSG00000103510	KAT8	100	99.127	ENSOGAG00000014452	KAT8	100	99.127	Otolemur_garnettii
ENSG00000103510	KAT8	100	97.598	ENSOARG00000008744	KAT8	100	97.598	Ovis_aries
ENSG00000103510	KAT8	100	99.786	ENSPPAG00000015780	KAT8	100	99.786	Pan_paniscus
ENSG00000103510	KAT8	100	98.908	ENSPPRG00000007446	KAT8	100	98.908	Panthera_pardus
ENSG00000103510	KAT8	99	99.459	ENSPTIG00000011561	KAT8	97	91.236	Panthera_tigris_altaica
ENSG00000103510	KAT8	100	99.782	ENSPTRG00000008034	KAT8	100	99.782	Pan_troglodytes
ENSG00000103510	KAT8	100	99.782	ENSPANG00000023250	KAT8	100	99.782	Papio_anubis
ENSG00000103510	KAT8	99	95.676	ENSPKIG00000025402	kat8	82	89.070	Paramormyrops_kingsleyae
ENSG00000103510	KAT8	73	90.441	ENSPMGG00000000784	kat8	80	79.938	Periophthalmus_magnuspinnatus
ENSG00000103510	KAT8	99	100.000	ENSPEMG00000022870	Kat8	100	98.472	Peromyscus_maniculatus_bairdii
ENSG00000103510	KAT8	99	98.919	ENSPCIG00000015907	KAT8	97	96.840	Phascolarctos_cinereus
ENSG00000103510	KAT8	99	91.892	ENSPFOG00000019613	kat8	93	84.327	Poecilia_formosa
ENSG00000103510	KAT8	99	91.892	ENSPLAG00000023280	kat8	92	81.057	Poecilia_latipinna
ENSG00000103510	KAT8	99	91.892	ENSPMEG00000011784	kat8	92	84.327	Poecilia_mexicana
ENSG00000103510	KAT8	99	92.432	ENSPREG00000011080	kat8	92	84.327	Poecilia_reticulata
ENSG00000103510	KAT8	100	99.563	ENSPPYG00000007308	KAT8	100	99.563	Pongo_abelii
ENSG00000103510	KAT8	99	100.000	ENSPCAG00000007568	KAT8	100	98.908	Procavia_capensis
ENSG00000103510	KAT8	99	100.000	ENSPCOG00000026965	KAT8	100	98.908	Propithecus_coquereli
ENSG00000103510	KAT8	99	100.000	ENSPVAG00000003091	KAT8	100	98.253	Pteropus_vampyrus
ENSG00000103510	KAT8	99	93.514	ENSPNYG00000009561	kat8	91	83.407	Pundamilia_nyererei
ENSG00000103510	KAT8	99	93.514	ENSPNAG00000019033	kat8	96	85.235	Pygocentrus_nattereri
ENSG00000103510	KAT8	99	99.459	ENSRNOG00000019585	Kat8	100	97.817	Rattus_norvegicus
ENSG00000103510	KAT8	100	99.782	ENSRBIG00000035411	KAT8	100	99.782	Rhinopithecus_bieti
ENSG00000103510	KAT8	100	99.782	ENSRROG00000038618	KAT8	100	99.782	Rhinopithecus_roxellana
ENSG00000103510	KAT8	100	98.908	ENSSBOG00000026858	KAT8	100	98.908	Saimiri_boliviensis_boliviensis
ENSG00000103510	KAT8	99	98.919	ENSSHAG00000011739	KAT8	95	95.730	Sarcophilus_harrisii
ENSG00000103510	KAT8	99	94.054	ENSSFOG00015006636	kat8	100	91.220	Scleropages_formosus
ENSG00000103510	KAT8	99	91.351	ENSSMAG00000011844	kat8	91	83.592	Scophthalmus_maximus
ENSG00000103510	KAT8	99	92.973	ENSSDUG00000005784	kat8	91	83.778	Seriola_dumerili
ENSG00000103510	KAT8	99	92.973	ENSSLDG00000003764	kat8	89	83.603	Seriola_lalandi_dorsalis
ENSG00000103510	KAT8	68	97.059	ENSSARG00000010230	KAT8	69	96.311	Sorex_araneus
ENSG00000103510	KAT8	84	72.956	ENSSPUG00000002938	KAT8	95	60.998	Sphenodon_punctatus
ENSG00000103510	KAT8	99	93.514	ENSSPAG00000006177	kat8	91	84.259	Stegastes_partitus
ENSG00000103510	KAT8	100	99.345	ENSSSCG00000031247	KAT8	100	99.345	Sus_scrofa
ENSG00000103510	KAT8	99	92.432	ENSTRUG00000003923	kat8	92	83.444	Takifugu_rubripes
ENSG00000103510	KAT8	99	92.432	ENSTNIG00000011297	kat8	92	83.664	Tetraodon_nigroviridis
ENSG00000103510	KAT8	99	100.000	ENSTBEG00000017391	KAT8	97	93.392	Tupaia_belangeri
ENSG00000103510	KAT8	99	100.000	ENSTTRG00000015552	KAT8	100	98.690	Tursiops_truncatus
ENSG00000103510	KAT8	100	99.127	ENSUAMG00000008546	KAT8	100	99.127	Ursus_americanus
ENSG00000103510	KAT8	99	99.459	ENSUMAG00000014072	KAT8	96	98.728	Ursus_maritimus
ENSG00000103510	KAT8	100	99.127	ENSVVUG00000027732	KAT8	97	99.127	Vulpes_vulpes
ENSG00000103510	KAT8	99	96.757	ENSXETG00000001943	kat8	91	90.802	Xenopus_tropicalis
ENSG00000103510	KAT8	99	90.909	ENSXCOG00000014255	kat8	95	82.989	Xiphophorus_couchianus
ENSG00000103510	KAT8	99	92.432	ENSXMAG00000001780	kat8	92	83.885	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000123	histone acetyltransferase complex	21873635.	IBA	Component
GO:0000123	histone acetyltransferase complex	20018852.	IDA	Component
GO:0000776	kinetochore	-	IEA	Component
GO:0000790	nuclear chromatin	21873635.	IBA	Component
GO:0004402	histone acetyltransferase activity	21873635.	IBA	Function
GO:0004402	histone acetyltransferase activity	11742995.	IDA	Function
GO:0005515	protein binding	11965546.15960975.16601686.22020126.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	11742995.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0008134	transcription factor binding	11742995.11965546.	IDA	Function
GO:0010506	regulation of autophagy	23863932.	IDA	Process
GO:0016363	nuclear matrix	-	IEA	Component
GO:0016407	acetyltransferase activity	11742995.	IDA	Function
GO:0016573	histone acetylation	11742995.	IDA	Process
GO:0019899	enzyme binding	-	IEA	Function
GO:0030099	myeloid cell differentiation	11742995.	IDA	Process
GO:0035064	methylated histone binding	15960975.	IDA	Function
GO:0042393	histone binding	21873635.	IBA	Function
GO:0043981	histone H4-K5 acetylation	20018852.	IDA	Process
GO:0043982	histone H4-K8 acetylation	20018852.	IDA	Process
GO:0043984	histone H4-K16 acetylation	20018852.	IDA	Process
GO:0043984	histone H4-K16 acetylation	15960975.	IMP	Process
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	20018852.	IDA	Function
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	20018852.	IDA	Function
GO:0045892	negative regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0045892	negative regulation of transcription, DNA-templated	11742995.	IDA	Process
GO:0045893	positive regulation of transcription, DNA-templated	11742995.11965546.	IDA	Process
GO:0045893	positive regulation of transcription, DNA-templated	15960975.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	21873635.	IBA	Function
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	20018852.	IDA	Function
GO:0071339	MLL1 complex	15960975.	IDA	Component
GO:0072487	MSL complex	21873635.	IBA	Component
GO:0072487	MSL complex	20018852.	IDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.