EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr8	98134007	Missense_Mutation	rs747730830	A265V	0.47
BLCA	chr8	98130173	Missense_Mutation	rs755335901	V228L	0.24
BLCA	chr8	98158122	Missense_Mutation	novel	V976I	0.21
BLCA	chr8	98127669	Missense_Mutation	novel	E73K	0.18
BLCA	chr8	98123470	Missense_Mutation	NA	Q45E	0.16
BLCA	chr8	98158180	Missense_Mutation	rs372595102	S995F	0.1
BLCA	chr8	98157734	Silent	novel	L846L	0.37
BLCA	chr8	98157666	Missense_Mutation	rs774195595	E824K	0.47
BLCA	chr8	98136705	Missense_Mutation	rs757794868	S412C	0.1
BLCA	chr8	98136858	Splice_Region	rs747236866		0.6
BRCA	chr8	98128538	Frame_Shift_Ins	novel	*E162Afs28**	0.07
BRCA	chr8	98150601	Silent	rs750752565	A673A	0.44
BRCA	chr8	98123444	Missense_Mutation	NA	S36T	0.18
BRCA	chr8	98157753	Missense_Mutation	novel	P853T	0.1
BRCA	chr8	98156063	Missense_Mutation	novel	K691E	0.08	POP1
BRCA	chr8	98158247	Missense_Mutation	NA	F1017L	0.12
BRCA	chr8	98134527	Silent	NA	V293V	0.5
BRCA	chr8	98156158	Nonsense_Mutation	NA	Y722*	0.12
BRCA	chr8	98148849	Missense_Mutation	novel	P582L	0.06
BRCA	chr8	98146593	Silent	novel	L540L	0.12
BRCA	chr8	98128538	Frame_Shift_Ins	novel	*E162Afs30**	0.1
BRCA	chr8	98157657	Missense_Mutation	NA	P821S	0.33
BRCA	chr8	98158576	3'Flank	novel		0.31
BRCA	chr8	98130158	Missense_Mutation	novel	G223R	0.08
CESC	chr8	98129990	Missense_Mutation	rs369456138	V167I	0.38
CESC	chr8	98148873	Missense_Mutation	novel	P590H	0.3
CESC	chr8	98156052	Missense_Mutation	rs146092766	R687H	0.4	POP1
CESC	chr8	98157917	Silent	novel	K907K	0.41
CESC	chr8	98158075	Missense_Mutation	novel	S960C	0.31
COAD	chr8	98148843	Missense_Mutation	novel	L580R	0.22
COAD	chr8	98127616	Missense_Mutation	rs767448528	R55Q	0.25
COAD	chr8	98128475	Nonsense_Mutation	rs374710242	R141*	0.4
COAD	chr8	98123388	Silent	NA	P17P	0.37
COAD	chr8	98158057	Missense_Mutation	rs765348522	R954H	0.3
COAD	chr8	98134475	Missense_Mutation	rs762273922	L276P	0.36
COAD	chr8	98157790	Missense_Mutation	novel	S865I	0.44
COAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.32
COAD	chr8	98134585	Missense_Mutation	novel	K313E	0.07
COAD	chr8	98150550	Silent	novel	S656S	0.08
COAD	chr8	98157655	Missense_Mutation	novel	G820E	0.05
COAD	chr8	98157614	Splice_Region	novel		0.27
COAD	chr8	98130212	Missense_Mutation	rs150132872	R241W	0.28
COAD	chr8	98128495	Silent	rs370950344	N147N	0.17
COAD	chr8	98136602	Missense_Mutation	rs772305728	E378K	0.44
COAD	chr8	98128423	Silent	NA	T123T	0.31
COAD	chr8	98136659	Frame_Shift_Del	NA	*I399Lfs23**	0.07
COAD	chr8	98150607	Silent	NA	E675E	0.4
COAD	chr8	98136659	Frame_Shift_Del	NA	*I399Lfs23**	0.12
COAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.16
COAD	chr8	98157901	Missense_Mutation	novel	D902G	0.17
COAD	chr8	98128467	Missense_Mutation	NA	H138R	0.37
COAD	chr8	98140109	Missense_Mutation	rs553476963	R465H	0.44
COAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.32
COAD	chr8	98136862	Missense_Mutation	rs781072902	D424N	0.3
ESCA	chr8	98158099	Missense_Mutation	novel	T968I	0.77
ESCA	chr8	98127717	Missense_Mutation	novel	A89S	0.1
GBM	chr8	98130122	Missense_Mutation	NA	R211W	0.46
GBM	chr8	98158031	Silent	novel	L945L	0.1
GBM	chr8	98156159	Missense_Mutation	novel	E723K	0.4
GBM	chr8	98156051	Missense_Mutation	rs142902409	R687C	0.41	POP1
HNSC	chr8	98134546	Missense_Mutation	novel	Y300H	0.25
HNSC	chr8	98146617	Silent	novel	C548C	0.24
HNSC	chr8	98158250	Silent	rs756017733	A1018A	0.06
KIRP	chr8	98156318	Missense_Mutation	novel	G776W	0.43
KIRP	chr8	98148920	Missense_Mutation	NA	V606M	0.34
KIRP	chr8	98140096	Nonsense_Mutation	NA	E461*	0.42
KIRP	chr8	98130117	Missense_Mutation	NA	A209V	0.41
LAML	chr8	98158146	Missense_Mutation	novel	F984L	0.12
LGG	chr8	98130170	Missense_Mutation	novel	T227A	0.06
LGG	chr8	98156140	Silent	novel	E716E	0.35
LIHC	chr8	98158102	Missense_Mutation	novel	Q969L	0.37
LIHC	chr8	98129967	Splice_Site	novel	X163_splice	0.13
LUAD	chr8	98157968	Silent	novel	G924G	0.11
LUAD	chr8	98157740	Missense_Mutation	NA	I848M	0.16
LUAD	chr8	98157682	Missense_Mutation	NA	G829D	0.34
LUAD	chr8	98156245	Silent	novel	K751K	0.21
LUAD	chr8	98136715	Silent	novel	S415S	0.16
LUAD	chr8	98123383	Nonsense_Mutation	NA	Q16*	0.08
LUAD	chr8	98158227	Missense_Mutation	NA	A1011S	0.22
LUAD	chr8	98136508	Silent	rs142413561	A346A	0.07
LUAD	chr8	98134523	Frame_Shift_Del	novel	*V293Cfs5**	0.23
LUAD	chr8	98156294	Missense_Mutation	novel	E768Q	0.18
LUAD	chr8	98156324	Nonsense_Mutation	rs771454414	Q778*	0.17
LUAD	chr8	98157953	Missense_Mutation	novel	K919N	0.36
LUAD	chr8	98157753	Missense_Mutation	novel	P853S	0.05
LUAD	chr8	98136862	Missense_Mutation	novel	D424Y	0.21
LUAD	chr8	98157676	Missense_Mutation	novel	R827L	0.2
LUAD	chr8	98146605	Silent	NA	V544V	0.29
LUAD	chr8	98156100	Missense_Mutation	novel	P703L	0.34	POP1
LUAD	chr8	98130117	Missense_Mutation	NA	A209V	0.27
LUAD	chr8	98148926	Missense_Mutation	NA	G608C	0.17
LUAD	chr8	98150563	Missense_Mutation	novel	G661C	0.27	POP1
LUAD	chr8	98158005	Missense_Mutation	novel	V937L	0.12
LUAD	chr8	98130093	Nonsense_Mutation	NA	W201*	0.42
LUAD	chr8	98148851	Missense_Mutation	novel	G583R	0.49
LUAD	chr8	98128512	Missense_Mutation	NA	R153I	0.39
LUSC	chr8	98158275	3'UTR	rs771532722		0.1
LUSC	chr8	98123455	Nonsense_Mutation	novel	K40*	0.32
LUSC	chr8	98127720	Missense_Mutation	novel	G90C	0.27
LUSC	chr8	98156114	Missense_Mutation	NA	W708R	0.21	POP1
LUSC	chr8	98134632	Missense_Mutation	novel	W328C	0.23
LUSC	chr8	98136548	Missense_Mutation	NA	A360S	0.43
LUSC	chr8	98128486	Missense_Mutation	novel	M144I	0.13
LUSC	chr8	98150601	Silent	novel	A673A	0.32
LUSC	chr8	98128513	Silent	rs771415317	R153R	0.42
LUSC	chr8	98136894	Silent	NA	L434L	0.23
LUSC	chr8	98156098	Silent	novel	A702A	0.16
LUSC	chr8	98127746	Frame_Shift_Del	novel	*K100Sfs3**	0.22
LUSC	chr8	98156367	Missense_Mutation	NA	S792I	0.38
LUSC	chr8	98158054	Missense_Mutation	rs761103255	P953L	0.32
LUSC	chr8	98127696	Nonsense_Mutation	novel	R82*	0.54
LUSC	chr8	98130183	Missense_Mutation	novel	H231R	0.23
OV	chr8	98150509	Missense_Mutation	NA	G643R	0.46	POP1
OV	chr8	98130131	Missense_Mutation	rs370059328	M214V	0.31
OV	chr8	98148997	Missense_Mutation	NA	W631C	0.26	POP1
OV	chr8	98157632	Silent	rs747381391	L812L	0.12
OV	chr8	98157707	Silent	novel	Q837Q	0.06
OV	chr8	98157698	Silent	novel	G834G	0.04
OV	chr8	98148946	Missense_Mutation	novel	W614C	0.06
PAAD	chr8	98140176	Missense_Mutation	novel	F487L	0.04
PAAD	chr8	98130075	Missense_Mutation	novel	R195K	0.18
PRAD	chr8	98133986	Missense_Mutation	novel	K258R	0.07
PRAD	chr8	98158308	3'UTR	rs752722442		0.61
READ	chr8	98130213	Missense_Mutation	rs148502433	R241Q	0.53
READ	chr8	98157899	Silent	NA	S901S	0.36
READ	chr8	98136671	Missense_Mutation	rs140243288	G401S	0.33
READ	chr8	98157649	Nonsense_Mutation	NA	W818*	0.57
READ	chr8	98148847	Silent	NA	V581V	0.22
READ	chr8	98156394	Missense_Mutation	NA	S801N	0.18
SARC	chr8	98130058	Silent	rs781451136	T189T	0.06
SKCM	chr8	98140176	Silent	rs777948013	F487F	0.43
SKCM	chr8	98156071	Silent	NA	P693P	0.21
SKCM	chr8	98156331	Missense_Mutation	rs149744031	S780L	0.32
SKCM	chr8	98158074	Missense_Mutation	NA	S960T	0.3
SKCM	chr8	98136487	Silent	NA	I339I	0.5
SKCM	chr8	98136521	Missense_Mutation	NA	E351K	0.12
SKCM	chr8	98134589	Missense_Mutation	NA	S314F	0.29
SKCM	chr8	98128434	Missense_Mutation	rs3824145	S127L	0.44
SKCM	chr8	98150491	Nonsense_Mutation	rs750817485	R637*	0.13	POP1
SKCM	chr8	98128434	Missense_Mutation	rs3824145	S127L	0.24
SKCM	chr8	98156390	Missense_Mutation	novel	G800R	0.19
SKCM	chr8	98158105	Missense_Mutation	novel	G970E	0.53
SKCM	chr8	98134589	Missense_Mutation	NA	S314F	0.25
SKCM	chr8	98134522	Missense_Mutation	NA	L292F	0.24
SKCM	chr8	98156277	Missense_Mutation	NA	S762F	0.43
SKCM	chr8	98150636	Missense_Mutation	NA	K685I	0.26	POP1
SKCM	chr8	98157990	Missense_Mutation	NA	A932S	0.32
SKCM	chr8	98130054	Missense_Mutation	rs747368799	R188Q	0.46
SKCM	chr8	98130056	Missense_Mutation	novel	T189A	0.45
SKCM	chr8	98136949	Missense_Mutation	NA	H453Y	0.63
SKCM	chr8	98130109	Silent	NA	I206I	0.25
SKCM	chr8	98140169	Missense_Mutation	NA	A485V	0.32
SKCM	chr8	98134530	Silent	NA	L294L	0.22
SKCM	chr8	98157760	Missense_Mutation	NA	A855V	0.25
SKCM	chr8	98140792	Missense_Mutation	NA	P500S	0.14
SKCM	chr8	98133956	Missense_Mutation	NA	S248F	0.07
SKCM	chr8	98127682	Missense_Mutation	NA	S77F	0.19
SKCM	chr8	98134007	Missense_Mutation	rs747730830	A265V	0.52
SKCM	chr8	98134549	Missense_Mutation	NA	P301S	0.65
STAD	chr8	98156051	Missense_Mutation	rs142902409	R687C	0.2	POP1
STAD	chr8	98134511	Missense_Mutation	rs144135573	R288H	0.2
STAD	chr8	98127685	Missense_Mutation	NA	K78R	0.16
STAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.12
STAD	chr8	98157803	Silent	rs772916913	P869P	0.14
STAD	chr8	98136659	Frame_Shift_Del	NA	*I399Lfs23**	0.12
STAD	chr8	98158023	Missense_Mutation	NA	L943M	0.21
STAD	chr8	98158004	Silent	rs146111575	P936P	0.24
STAD	chr8	98134619	Missense_Mutation	NA	S324N	0.1
STAD	chr8	98146585	Nonsense_Mutation	rs770043633	Q538*	0.27
STAD	chr8	98156191	Silent	rs764185469	G733G	0.28
STAD	chr8	98123427	Missense_Mutation	NA	R30S	0.09
STAD	chr8	98127744	Missense_Mutation	NA	I98L	0.38
STAD	chr8	98127708	Nonsense_Mutation	rs150709391	G86*	0.16
STAD	chr8	98128415	Missense_Mutation	novel	A121T	0.29
STAD	chr8	98134535	Missense_Mutation	rs371524249	R296Q	0.26
STAD	chr8	98136532	Missense_Mutation	novel	K354N	0.32
STAD	chr8	98156255	Missense_Mutation	novel	P755S	0.04
STAD	chr8	98156322	Missense_Mutation	novel	C777Y	0.25
STAD	chr8	98158275	3'UTR	rs771532722		0.39
STAD	chr8	98130122	Missense_Mutation	NA	R211W	0.4
STAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.2
STAD	chr8	98136891	Silent	NA	R433R	0.46
STAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.23
STAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.11
STAD	chr8	98127709	Missense_Mutation	NA	G86E	0.17
STAD	chr8	98136659	Nonsense_Mutation	NA	K397*	0.2
STAD	chr8	98156240	Frame_Shift_Del	NA	*T752Lfs12**	0.25
STAD	chr8	98157837	Missense_Mutation	NA	E881K	0.75
STAD	chr8	98150635	Frame_Shift_Del	novel	*R686Dfs26**	0.34	POP1
STAD	chr8	98156106	Missense_Mutation	NA	C705Y	0.25	POP1
STAD	chr8	98156297	Missense_Mutation	NA	A769T	0.12
THCA	chr8	98148853	Silent	novel	G583G	0.08
THYM	chr8	98157696	Missense_Mutation	rs751972489	G834S	0.31
UCEC	chr8	98130083	Missense_Mutation	NA	K198E	0.33
UCEC	chr8	98140820	Missense_Mutation	novel	V509D	0.48
UCEC	chr8	98130035	Nonsense_Mutation	rs146339637	R182*	0.32
UCEC	chr8	98157969	Missense_Mutation	novel	R925C	0.5
UCEC	chr8	98128435	Silent	rs149813274	S127S	0.16
UCEC	chr8	98134033	Missense_Mutation	rs765570863	T274A	0.49
UCEC	chr8	98134520	Missense_Mutation	NA	S291N	0.25
UCEC	chr8	98140832	Missense_Mutation	rs754139444	R513Q	0.51
UCEC	chr8	98134036	Missense_Mutation	novel	G275R	0.36
UCEC	chr8	98128460	Missense_Mutation	novel	P136S	0.24
UCEC	chr8	98156052	Missense_Mutation	rs146092766	R687H	0.41	POP1
UCEC	chr8	98134575	Silent	rs374380026	T309T	0.46
UCEC	chr8	98136869	Missense_Mutation	rs748242967	T426M	0.36
UCEC	chr8	98148824	Missense_Mutation	rs149886997	R574W	0.46
UCEC	chr8	98130213	Missense_Mutation	rs148502433	R241Q	0.22
UCEC	chr8	98156374	Frame_Shift_Ins	novel	*H795Ifs22**	0.06
UCEC	chr8	98127596	Splice_Region	NA	E48E	0.21
UCEC	chr8	98134023	Silent	NA	C270C	0.13
UCEC	chr8	98134602	Silent	novel	P318P	0.23
UCEC	chr8	98127726	Missense_Mutation	rs757141424	E92K	0.19
UCEC	chr8	98146650	Silent	rs757002385	C559C	0.24
UCEC	chr8	98150549	Missense_Mutation	rs769863408	S656L	0.25	POP1
UCEC	chr8	98157971	Silent	rs202047999	R925R	0.77
UCEC	chr8	98130053	Missense_Mutation	rs758854821	R188W	0.58
UCEC	chr8	98158242	Nonsense_Mutation	novel	R1016*	0.41
UCEC	chr8	98148907	Silent	novel	Q601Q	0.3
UCEC	chr8	98149007	Splice_Site	novel	X634_splice	0.09
UCEC	chr8	98146677	Silent	rs770094585	S568S	0.45
UCEC	chr8	98158243	Missense_Mutation	NA	R1016Q	0.38
UCEC	chr8	98127693	Missense_Mutation	novel	F81L	0.44
UCEC	chr8	98128515	Missense_Mutation	rs746242376	R154Q	0.58
UCEC	chr8	98146591	Missense_Mutation	novel	L540I	0.32
UCEC	chr8	98158001	Silent	novel	E935E	0.3
UCEC	chr8	98128538	Splice_Region	novel	E162delinsAYLRYRYK	0.09
UCEC	chr8	98140824	Silent	NA	G510G	0.38
UCEC	chr8	98156338	Silent	novel	G782G	0.41
UCEC	chr8	98128435	Silent	rs149813274	S127S	0.43
UCEC	chr8	98157941	Missense_Mutation	NA	K915N	0.26
UCEC	chr8	98156323	Silent	novel	C777C	0.33
UCEC	chr8	98128538	Splice_Region	novel	E162delinsAYLRYRYK	0.19
UCEC	chr8	98140832	Missense_Mutation	rs754139444	R513Q	0.38
UCEC	chr8	98150616	Missense_Mutation	novel	K678N	0.34	POP1
UCEC	chr8	98157818	Missense_Mutation	novel	M874I	0.2
UCEC	chr8	98156149	Silent	novel	V719V	0.29
UCEC	chr8	98127734	Silent	rs373623359	T94T	0.31
UCEC	chr8	98156068	Silent	novel	R692R	0.35
UCEC	chr8	98136862	Missense_Mutation	rs781072902	D424N	0.43
UCEC	chr8	98140832	Missense_Mutation	rs754139444	R513Q	0.32
UCEC	chr8	98158242	Nonsense_Mutation	novel	R1016*	0.32
UCEC	chr8	98156051	Missense_Mutation	rs142902409	R687C	0.38	POP1
UCEC	chr8	98136481	Splice_Site	novel	X338_splice	0.06
UCEC	chr8	98128446	Frame_Shift_Del	NA	*Q133Rfs12**	0.08
UCEC	chr8	98156052	Missense_Mutation	rs146092766	R687H	0.33	POP1
UCEC	chr8	98128464	Missense_Mutation	rs150791484	R137Q	0.35
UCEC	chr8	98136658	Frame_Shift_Ins	rs762132704	*I399Nfs4**	0.36
UCEC	chr8	98128538	Frame_Shift_Ins	novel	*E162Afs30**	0.06
UCEC	chr8	98130058	Silent	rs781451136	T189T	0.4
UCEC	chr8	98157775	Missense_Mutation	novel	S860N	0.24
UCEC	chr8	98158296	3'UTR	novel		0.35
UCEC	chr8	98134028	Missense_Mutation	rs754287651	I272T	0.21
UCEC	chr8	98157867	Missense_Mutation	NA	H891Y	0.36
UCEC	chr8	98140177	Missense_Mutation	NA	E488K	0.44
UCEC	chr8	98140851	Missense_Mutation	NA	K519N	0.46
UCEC	chr8	98157941	Missense_Mutation	NA	K915N	0.47
UCEC	chr8	98157685	Missense_Mutation	rs753385823	R830Q	0.24
UCEC	chr8	98157970	Missense_Mutation	rs756634206	R925H	0.7
UCEC	chr8	98130005	Nonsense_Mutation	novel	E172*	0.25
UCEC	chr8	98127709	Missense_Mutation	NA	G86E	0.19
UCEC	chr8	98128435	Silent	rs149813274	S127S	0.46
UCEC	chr8	98129977	Splice_Site	novel	X163_splice	0.21
UCEC	chr8	98128435	Silent	rs149813274	S127S	0.39
UCEC	chr8	98128497	Missense_Mutation	novel	V148A	0.44
UCEC	chr8	98157990	Missense_Mutation	novel	A932T	0.3
UCEC	chr8	98146685	Splice_Site	novel	X570_splice	0.37
UCS	chr8	98127684	Missense_Mutation	novel	K78E	0.37
UCS	chr8	98130134	Missense_Mutation	novel	V215I	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	AMP	0.1042	0.15559
PRAD	AMP	0.2642	3.7005e-05
SARC	AMP	0.2879	0.18425
TGCT	AMP	0.66	0.13696
THCA	DEL	0.008	0.038162

Survival Analysis

Cancer	P-value	Q-value
STAD	0.017	Kaplan-Meier Survival Analysis
SARC	0.0013	Kaplan-Meier Survival Analysis
MESO	0.00037	Kaplan-Meier Survival Analysis
ACC	0.00038	Kaplan-Meier Survival Analysis
PRAD	0.027	Kaplan-Meier Survival Analysis
BRCA	0.0021	Kaplan-Meier Survival Analysis
KIRP	0.0016	Kaplan-Meier Survival Analysis
COAD	0.034	Kaplan-Meier Survival Analysis
READ	0.0084	Kaplan-Meier Survival Analysis
LAML	0.049	Kaplan-Meier Survival Analysis
KICH	0.0047	Kaplan-Meier Survival Analysis
UCEC	0.02	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
LGG	0.012	Kaplan-Meier Survival Analysis
LUAD	0.016	Kaplan-Meier Survival Analysis
UVM	0.005	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000104356 (Gene tree)
Gene ID: 10940
Gene Symbol: POP1
Alias: N
Full Name: POP1 homolog, ribonuclease P/MRP subunit
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 42,549 bases
Position: chr8:98,117,293-98,159,841
Accession: 30129
RBP type: canonical RBP
Summary: This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000339529	POP1	PF06978.11	4.8e-38	1	2
ENSP00000339529	POP1	PF06978.11	4.8e-38	2	2
ENSP00000385787	POP1	PF06978.11	4.8e-38	1	2
ENSP00000385787	POP1	PF06978.11	4.8e-38	2	2
ENSP00000428945	POP1	PF06978.11	1.3e-17	1	1
ENSP00000339529	POPLD	PF08170.12	3.5e-27	1	1
ENSP00000385787	POPLD	PF08170.12	3.5e-27	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
27156450	Active Yeast Telomerase Shares Subunits with Ribonucleoproteins RNase P and RNase MRP.	Cell	2016 May 19	Lemieux B	doi: 10.1016/j.cell.2016.04.018

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000517435	POP1-203	506	-	-	- (aa)	-	-
ENST00000401707	POP1-202	4719	XM_011516801	ENSP00000385787	1024 (aa)	XP_011515103	Q99575
ENST00000522319	POP1-204	585	-	ENSP00000428945	183 (aa)	-	E5RK39
ENST00000349693	POP1-201	3244	-	ENSP00000339529	1024 (aa)	-	Q99575

Gene Model

Click here to download ENSG00000104356's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000104356	Body Height	2.6670000E-005	-
ENSG00000104356	Platelet Function Tests	3.0591600E-005	-
ENSG00000104356	Prion Diseases	9E-6	22210626

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000104356's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000104356	POP1	100	48.582	ENSAPOG00000008198	pop1	100	48.488	Acanthochromis_polyacanthus
ENSG00000104356	POP1	100	85.714	ENSAMEG00000000556	POP1	100	80.971	Ailuropoda_melanoleuca
ENSG00000104356	POP1	90	49.575	ENSACIG00000004169	POP1	100	46.565	Amphilophus_citrinellus
ENSG00000104356	POP1	100	47.358	ENSAOCG00000010991	pop1	100	47.398	Amphiprion_ocellaris
ENSG00000104356	POP1	91	47.580	ENSAPEG00000007607	pop1	96	48.037	Amphiprion_percula
ENSG00000104356	POP1	100	45.938	ENSATEG00000024814	POP1	100	46.328	Anabas_testudineus
ENSG00000104356	POP1	92	63.617	ENSAPLG00000014418	POP1	100	63.617	Anas_platyrhynchos
ENSG00000104356	POP1	100	56.551	ENSACAG00000016083	POP1	100	56.625	Anolis_carolinensis
ENSG00000104356	POP1	100	90.164	ENSANAG00000026360	POP1	100	93.472	Aotus_nancymaae
ENSG00000104356	POP1	100	47.974	ENSACLG00000010951	pop1	100	47.970	Astatotilapia_calliptera
ENSG00000104356	POP1	100	45.772	ENSAMXG00000014483	POP1	100	45.120	Astyanax_mexicanus
ENSG00000104356	POP1	100	87.978	ENSBTAG00000012596	POP1	100	80.762	Bos_taurus
ENSG00000104356	POP1	100	93.066	ENSCJAG00000015567	POP1	100	93.066	Callithrix_jacchus
ENSG00000104356	POP1	100	90.164	ENSCAFG00000000469	POP1	100	81.250	Canis_familiaris
ENSG00000104356	POP1	100	90.164	ENSCAFG00020026765	POP1	100	82.520	Canis_lupus_dingo
ENSG00000104356	POP1	100	88.525	ENSCHIG00000017066	POP1	100	80.878	Capra_hircus
ENSG00000104356	POP1	100	91.257	ENSTSYG00000003097	POP1	100	86.719	Carlito_syrichta
ENSG00000104356	POP1	100	88.525	ENSCAPG00000007251	POP1	100	78.426	Cavia_aperea
ENSG00000104356	POP1	100	88.525	ENSCPOG00000002901	POP1	100	81.152	Cavia_porcellus
ENSG00000104356	POP1	100	96.721	ENSCCAG00000018939	POP1	100	92.871	Cebus_capucinus
ENSG00000104356	POP1	100	98.361	ENSCATG00000040916	POP1	100	96.875	Cercocebus_atys
ENSG00000104356	POP1	100	90.164	ENSCLAG00000007208	POP1	97	82.520	Chinchilla_lanigera
ENSG00000104356	POP1	90	96.204	ENSCSAG00000012340	POP1	99	96.204	Chlorocebus_sabaeus
ENSG00000104356	POP1	95	80.635	ENSCHOG00000011432	POP1	100	80.225	Choloepus_hoffmanni
ENSG00000104356	POP1	100	68.280	ENSCPBG00000006373	POP1	100	65.272	Chrysemys_picta_bellii
ENSG00000104356	POP1	82	38.132	ENSCING00000008323	-	90	36.396	Ciona_intestinalis
ENSG00000104356	POP1	100	98.907	ENSCANG00000001647	POP1	100	96.777	Colobus_angolensis_palliatus
ENSG00000104356	POP1	100	82.514	ENSCGRG00001017308	Pop1	100	76.465	Cricetulus_griseus_chok1gshd
ENSG00000104356	POP1	100	72.678	ENSCGRG00000010824	Pop1	100	70.898	Cricetulus_griseus_crigri
ENSG00000104356	POP1	100	45.877	ENSCSEG00000008737	POP1	100	46.161	Cynoglossus_semilaevis
ENSG00000104356	POP1	100	47.333	ENSCVAG00000022248	pop1	100	47.092	Cyprinodon_variegatus
ENSG00000104356	POP1	51	53.608	ENSDARG00000102087	pop1	94	48.590	Danio_rerio
ENSG00000104356	POP1	100	86.631	ENSDNOG00000019974	POP1	100	78.228	Dasypus_novemcinctus
ENSG00000104356	POP1	89	84.663	ENSDORG00000015384	Pop1	100	72.390	Dipodomys_ordii
ENSG00000104356	POP1	61	32.120	FBgn0026702	l(1)G0045	71	31.882	Drosophila_melanogaster
ENSG00000104356	POP1	100	80.328	ENSETEG00000007839	POP1	88	71.053	Echinops_telfairi
ENSG00000104356	POP1	51	54.255	ENSEBUG00000009897	pop1	88	46.742	Eptatretus_burgeri
ENSG00000104356	POP1	100	90.164	ENSEASG00005003189	POP1	98	84.277	Equus_asinus_asinus
ENSG00000104356	POP1	100	91.257	ENSECAG00000024236	POP1	100	84.277	Equus_caballus
ENSG00000104356	POP1	67	77.778	ENSEEUG00000003050	-	70	77.778	Erinaceus_europaeus
ENSG00000104356	POP1	100	47.533	ENSELUG00000003526	pop1	100	47.104	Esox_lucius
ENSG00000104356	POP1	100	89.617	ENSFCAG00000002168	POP1	100	84.180	Felis_catus
ENSG00000104356	POP1	100	60.847	ENSFALG00000005711	POP1	100	60.907	Ficedula_albicollis
ENSG00000104356	POP1	100	89.617	ENSFDAG00000017068	POP1	100	82.715	Fukomys_damarensis
ENSG00000104356	POP1	100	47.188	ENSFHEG00000019518	pop1	100	47.474	Fundulus_heteroclitus
ENSG00000104356	POP1	93	45.998	ENSGMOG00000000659	POP1	98	45.998	Gadus_morhua
ENSG00000104356	POP1	100	47.642	ENSGAFG00000019770	POP1	100	47.110	Gambusia_affinis
ENSG00000104356	POP1	100	46.958	ENSGACG00000003499	pop1	100	46.578	Gasterosteus_aculeatus
ENSG00000104356	POP1	100	64.211	ENSGAGG00000011737	POP1	98	64.147	Gopherus_agassizii
ENSG00000104356	POP1	100	99.121	ENSGGOG00000003176	POP1	100	99.121	Gorilla_gorilla
ENSG00000104356	POP1	100	47.834	ENSHBUG00000021583	pop1	100	47.781	Haplochromis_burtoni
ENSG00000104356	POP1	100	87.432	ENSHGLG00000006029	POP1	100	82.227	Heterocephalus_glaber_female
ENSG00000104356	POP1	100	87.432	ENSHGLG00100016879	POP1	100	82.227	Heterocephalus_glaber_male
ENSG00000104356	POP1	90	49.679	ENSHCOG00000013888	pop1	96	49.679	Hippocampus_comes
ENSG00000104356	POP1	100	44.918	ENSIPUG00000018336	pop1	91	62.651	Ictalurus_punctatus
ENSG00000104356	POP1	100	90.164	ENSSTOG00000011455	POP1	97	83.887	Ictidomys_tridecemlineatus
ENSG00000104356	POP1	100	87.978	ENSJJAG00000013325	Pop1	100	78.516	Jaculus_jaculus
ENSG00000104356	POP1	100	46.692	ENSKMAG00000001346	POP1	100	46.596	Kryptolebias_marmoratus
ENSG00000104356	POP1	89	48.488	ENSLBEG00000024457	POP1	95	47.780	Labrus_bergylta
ENSG00000104356	POP1	93	55.980	ENSLACG00000012498	POP1	99	55.844	Latimeria_chalumnae
ENSG00000104356	POP1	100	51.527	ENSLOCG00000009817	POP1	100	51.149	Lepisosteus_oculatus
ENSG00000104356	POP1	100	86.631	ENSLAFG00000010770	POP1	100	83.755	Loxodonta_africana
ENSG00000104356	POP1	100	98.907	ENSMFAG00000000347	POP1	100	96.582	Macaca_fascicularis
ENSG00000104356	POP1	100	98.907	ENSMNEG00000036870	POP1	100	95.996	Macaca_nemestrina
ENSG00000104356	POP1	100	98.907	ENSMLEG00000034986	POP1	100	96.484	Mandrillus_leucophaeus
ENSG00000104356	POP1	100	47.214	ENSMAMG00000004040	pop1	100	47.214	Mastacembelus_armatus
ENSG00000104356	POP1	100	48.023	ENSMZEG00005025448	pop1	100	47.970	Maylandia_zebra
ENSG00000104356	POP1	100	58.215	ENSMGAG00000012167	POP1	100	58.846	Meleagris_gallopavo
ENSG00000104356	POP1	100	84.699	ENSMAUG00000017537	Pop1	100	76.878	Mesocricetus_auratus
ENSG00000104356	POP1	100	90.710	ENSMICG00000004361	POP1	100	87.695	Microcebus_murinus
ENSG00000104356	POP1	100	83.607	ENSMOCG00000006356	Pop1	100	76.465	Microtus_ochrogaster
ENSG00000104356	POP1	100	44.704	ENSMMOG00000018242	pop1	100	44.704	Mola_mola
ENSG00000104356	POP1	100	71.429	ENSMODG00000006561	POP1	100	69.729	Monodelphis_domestica
ENSG00000104356	POP1	93	51.962	ENSMALG00000012621	POP1	100	47.543	Monopterus_albus
ENSG00000104356	POP1	100	85.792	MGP_CAROLIEiJ_G0019726	Pop1	100	76.758	Mus_caroli
ENSG00000104356	POP1	100	85.792	ENSMUSG00000022325	Pop1	100	77.246	Mus_musculus
ENSG00000104356	POP1	100	86.339	MGP_PahariEiJ_G0019735	Pop1	100	77.051	Mus_pahari
ENSG00000104356	POP1	100	86.885	MGP_SPRETEiJ_G0020622	Pop1	100	76.660	Mus_spretus
ENSG00000104356	POP1	100	89.674	ENSMPUG00000015250	POP1	100	81.518	Mustela_putorius_furo
ENSG00000104356	POP1	100	87.978	ENSMLUG00000010204	POP1	100	77.388	Myotis_lucifugus
ENSG00000104356	POP1	100	90.710	ENSNGAG00000001582	Pop1	100	82.520	Nannospalax_galili
ENSG00000104356	POP1	89	48.394	ENSNBRG00000002356	pop1	94	48.514	Neolamprologus_brichardi
ENSG00000104356	POP1	100	97.814	ENSNLEG00000002541	POP1	100	97.070	Nomascus_leucogenys
ENSG00000104356	POP1	93	61.169	ENSMEUG00000003118	POP1	98	61.169	Notamacropus_eugenii
ENSG00000104356	POP1	100	86.885	ENSOPRG00000007667	POP1	100	79.199	Ochotona_princeps
ENSG00000104356	POP1	100	89.071	ENSODEG00000003984	POP1	100	80.409	Octodon_degus
ENSG00000104356	POP1	100	48.433	ENSONIG00000016445	pop1	100	48.393	Oreochromis_niloticus
ENSG00000104356	POP1	89	69.512	ENSOANG00000001278	-	94	70.122	Ornithorhynchus_anatinus
ENSG00000104356	POP1	100	85.561	ENSOCUG00000017400	POP1	100	82.216	Oryctolagus_cuniculus
ENSG00000104356	POP1	100	47.172	ENSORLG00000002839	pop1	100	47.172	Oryzias_latipes
ENSG00000104356	POP1	90	49.893	ENSORLG00020022450	POP1	96	49.469	Oryzias_latipes_hni
ENSG00000104356	POP1	100	47.793	ENSORLG00015012746	POP1	100	47.843	Oryzias_latipes_hsok
ENSG00000104356	POP1	100	47.969	ENSOMEG00000006915	pop1	99	47.485	Oryzias_melastigma
ENSG00000104356	POP1	100	86.885	ENSOGAG00000001466	POP1	100	84.863	Otolemur_garnettii
ENSG00000104356	POP1	100	100.000	ENSPPAG00000018410	POP1	100	99.316	Pan_paniscus
ENSG00000104356	POP1	100	89.071	ENSPPRG00000005002	POP1	100	84.098	Panthera_pardus
ENSG00000104356	POP1	100	89.071	ENSPTIG00000016527	POP1	100	84.488	Panthera_tigris_altaica
ENSG00000104356	POP1	100	100.000	ENSPTRG00000020458	POP1	100	99.316	Pan_troglodytes
ENSG00000104356	POP1	100	98.361	ENSPANG00000009704	POP1	100	96.191	Papio_anubis
ENSG00000104356	POP1	100	49.425	ENSPKIG00000016325	POP1	100	48.848	Paramormyrops_kingsleyae
ENSG00000104356	POP1	100	66.316	ENSPSIG00000012343	POP1	100	63.725	Pelodiscus_sinensis
ENSG00000104356	POP1	90	49.306	ENSPMGG00000022253	POP1	95	49.573	Periophthalmus_magnuspinnatus
ENSG00000104356	POP1	99	82.967	ENSPEMG00000023633	Pop1	100	75.789	Peromyscus_maniculatus_bairdii
ENSG00000104356	POP1	90	44.034	ENSPMAG00000003209	POP1	100	43.776	Petromyzon_marinus
ENSG00000104356	POP1	100	72.396	ENSPCIG00000012216	POP1	100	68.147	Phascolarctos_cinereus
ENSG00000104356	POP1	100	48.752	ENSPFOG00000012490	POP1	100	48.219	Poecilia_formosa
ENSG00000104356	POP1	100	48.607	ENSPLAG00000004646	POP1	100	48.073	Poecilia_latipinna
ENSG00000104356	POP1	100	48.755	ENSPMEG00000019592	POP1	100	48.223	Poecilia_mexicana
ENSG00000104356	POP1	100	48.654	ENSPREG00000020951	POP1	100	48.316	Poecilia_reticulata
ENSG00000104356	POP1	100	99.454	ENSPPYG00000018777	POP1	100	97.754	Pongo_abelii
ENSG00000104356	POP1	100	83.060	ENSPCAG00000016662	POP1	100	75.902	Procavia_capensis
ENSG00000104356	POP1	100	90.164	ENSPCOG00000019420	POP1	100	87.988	Propithecus_coquereli
ENSG00000104356	POP1	100	85.792	ENSPVAG00000014468	POP1	100	82.732	Pteropus_vampyrus
ENSG00000104356	POP1	89	49.032	ENSPNYG00000004476	pop1	99	47.972	Pundamilia_nyererei
ENSG00000104356	POP1	100	45.638	ENSPNAG00000000265	pop1	100	43.893	Pygocentrus_nattereri
ENSG00000104356	POP1	100	84.153	ENSRNOG00000005243	Pop1	100	77.832	Rattus_norvegicus
ENSG00000104356	POP1	100	98.361	ENSRBIG00000007996	POP1	100	96.680	Rhinopithecus_bieti
ENSG00000104356	POP1	100	98.907	ENSRROG00000012334	POP1	100	96.875	Rhinopithecus_roxellana
ENSG00000104356	POP1	99	93.874	ENSSBOG00000020830	POP1	100	93.874	Saimiri_boliviensis_boliviensis
ENSG00000104356	POP1	100	69.841	ENSSHAG00000000296	POP1	100	68.925	Sarcophilus_harrisii
ENSG00000104356	POP1	100	48.473	ENSSFOG00015007429	pop1	99	47.947	Scleropages_formosus
ENSG00000104356	POP1	87	53.284	ENSSMAG00000010467	POP1	99	48.835	Scophthalmus_maximus
ENSG00000104356	POP1	100	46.792	ENSSDUG00000007817	POP1	100	47.081	Seriola_dumerili
ENSG00000104356	POP1	100	46.786	ENSSLDG00000012565	POP1	100	47.925	Seriola_lalandi_dorsalis
ENSG00000104356	POP1	61	75.676	ENSSARG00000002421	-	51	76.471	Sorex_araneus
ENSG00000104356	POP1	100	66.304	ENSSPUG00000003550	-	100	59.826	Sphenodon_punctatus
ENSG00000104356	POP1	100	47.144	ENSSPAG00000014955	pop1	100	47.241	Stegastes_partitus
ENSG00000104356	POP1	100	87.978	ENSSSCG00000006078	POP1	100	82.227	Sus_scrofa
ENSG00000104356	POP1	92	57.672	ENSTGUG00000012011	-	100	57.672	Taeniopygia_guttata
ENSG00000104356	POP1	91	48.520	ENSTRUG00000010856	pop1	94	48.520	Takifugu_rubripes
ENSG00000104356	POP1	92	49.117	ENSTNIG00000013297	pop1	99	49.066	Tetraodon_nigroviridis
ENSG00000104356	POP1	95	81.679	ENSTBEG00000014214	POP1	100	81.679	Tupaia_belangeri
ENSG00000104356	POP1	100	86.339	ENSTTRG00000016071	POP1	100	80.566	Tursiops_truncatus
ENSG00000104356	POP1	99	78.677	ENSUAMG00000017309	POP1	100	78.776	Ursus_americanus
ENSG00000104356	POP1	100	89.071	ENSUMAG00000016952	POP1	100	90.283	Ursus_maritimus
ENSG00000104356	POP1	100	86.885	ENSVPAG00000008278	POP1	82	87.956	Vicugna_pacos
ENSG00000104356	POP1	100	89.617	ENSVVUG00000010994	POP1	100	82.617	Vulpes_vulpes
ENSG00000104356	POP1	100	43.495	ENSXCOG00000017043	POP1	100	43.008	Xiphophorus_couchianus
ENSG00000104356	POP1	100	47.839	ENSXMAG00000002472	POP1	100	47.303	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000171	ribonuclease MRP activity	21873635.	IBA	Function
GO:0000171	ribonuclease MRP activity	8918471.	IDA	Function
GO:0000172	ribonuclease MRP complex	21873635.	IBA	Component
GO:0000172	ribonuclease MRP complex	8918471.16723659.	IDA	Component
GO:0001682	tRNA 5'-leader removal	16723659.30454648.	IDA	Process
GO:0001682	tRNA 5'-leader removal	-	TAS	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0004526	ribonuclease P activity	21873635.	IBA	Function
GO:0004526	ribonuclease P activity	8918471.	IDA	Function
GO:0004526	ribonuclease P activity	16723659.30454648.	IDA	Function
GO:0005515	protein binding	15096576.	IPI	Function
GO:0005615	extracellular space	22664934.	HDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005655	nucleolar ribonuclease P complex	21873635.	IBA	Component
GO:0005655	nucleolar ribonuclease P complex	8918471.	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0008033	tRNA processing	21873635.	IBA	Process
GO:0016078	tRNA catabolic process	8918471.	IDA	Process
GO:0030681	multimeric ribonuclease P complex	16723659.30454648.	IDA	Component
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.