EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28656261	lncRNA XIST interacts with miR-140 to modulate lung cancer growth by targeting iASPP.	Oncol Rep	2017 Aug	Tang Y	doi: 10.3892/or.2017.5751
24405603	[Expressions and clinical significances of iASPP and caspase-9 in esophageal cancer].	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi	2014 Jan	Kou W	-
27765948	Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124.	Sci Rep	2016 Oct 21	Dong P	doi: 10.1038/srep35480.
29072696	iASPP facilitates tumor growth by promoting mTOR-dependent autophagy in human non-small-cell lung cancer.	Cell Death Dis	2017 Oct 26	Xue Y	doi: 10.1038/cddis.2017.515.
22538442	iASPP inhibits p53-independent apoptosis by inhibiting transcriptional activity of p63/p73 on promoters of proapoptotic genes.	Apoptosis	2012 Aug	Cai Y	doi: 10.1007/s10495-012-0728-z.
24966937	MicroRNA124 regulate cell growth of prostate cancer cells by targeting iASPP.	Int J Clin Exp Pathol	2014 Apr 15	Chen J	-
28137422	The lncRNA UCA1 interacts with miR-182 to modulate glioma proliferation and migration by targeting iASPP.	Arch Biochem Biophys	2017 Jun 1	He Z	doi: 10.1016/j.abb.2017.01.013
21625267	Inhibitory member of the apoptosis-stimulating protein of p53 (ASPP) family promotes growth and tumorigenesis in human p53-deficient prostate cancer cells.	Prostate Cancer Prostatic Dis	2011 Sep	Zhang B	doi: 10.1038/pcan.2011.25
20354815	Genetic polymorphisms in ATM, ERCC1, APE1 and iASPP genes and lung cancer risk in a population of southeast China.	Med Oncol	2011 Sep	Deng Q	doi: 10.1007/s12032-010-9507-2
28489738	Inhibitory member of the apoptosis-stimulating protein of p53 is overexpressed in bladder cancer and correlated to its progression.	Medicine (Baltimore)	2017 May	Wu Z	doi: 10.1097/MD.0000000000006640.
30128886	GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population.	Curr Med Sci	2018 Aug	Yin JY	doi: 10.1007/s11596-018-1938-6
18289367	A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study.	BMC Cancer	2008 Feb 20	Hansen RD	doi: 10.1186/1471-2407-8-54.
20422457	Polymorphisms in apoptosis-related genes and survival of patients with early-stage non-small-cell lung cancer.	Ann Surg Oncol	2010 Oct	Lee EB	doi: 10.1245/s10434-010-1082-4
24140460	HapMap-based study identifies risk sub-region on chromosome 19q13.3 in relation to lung cancer among Chinese.	Cancer Epidemiol	2013 Dec	Yin J	doi: 10.1016/j.canep.2013.09.016
21192816	iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway.	BMC Cancer	2010 Dec 30	Chen J	doi: 10.1186/1471-2407-10-694.
23528480	Helicobacter pylori infection and expressions of apoptosis-related proteins p53, ASPP2 and iASPP in gastric cancer and precancerous lesions.	Pathol Biol (Paris)	2013 Oct	Meng WD	doi: 10.1016/j.patbio.2013.02.002
21926165	iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe.	Clin Cancer Res	2011 Nov 1	Jiang L	doi: 10.1158/1078-0432.CCR-11-0588
25917613	NFKB1 common variants and PPP1R13L and CD3EAP in relation to lung cancer risk in a Chinese population.	Gene	2015 Aug 1	Yin J	doi: 10.1016/j.gene.2015.04.059
25341046	Nuclear iASPP may facilitate prostate cancer progression.	Cell Death Dis	2014 Oct 23	Morris EV	doi: 10.1038/cddis.2014.442.
23624123	Effects of PPP1R13L and CD3EAP variants on lung cancer susceptibility among nonsmoking Chinese women.	Gene	2013 Jul 25	Yin J	doi: 10.1016/j.gene.2013.04.017
23180017	PPP1R13L variant associated with prognosis for patients with rectal cancer.	J Cancer Res Clin Oncol	2013 Mar	Chae YS	doi: 10.1007/s00432-012-1346-4
23420450	Elevated expression of iASPP correlates with poor prognosis and chemoresistance/radioresistance in FIGO Ib1-IIa squamous cell cervical cancer.	Cell Tissue Res	2013 May	Cao L	doi: 10.1007/s00441-013-1569-y
15885892	Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer.	Cancer Lett	2005 Jul 28	Laska MJ	-
26563375	Association and interaction of NFKB1 rs28362491 insertion/deletion ATTG polymorphism and PPP1R13L and CD3EAP related to lung cancer risk in a Chinese population.	Tumour Biol	2016 Apr	Yin J	doi: 10.1007/s13277-015-4373-3
22552744	Abnormal expression pattern of the ASPP family of proteins in human non-small cell lung cancer and regulatory functions on apoptosis through p53 by iASPP.	Oncol Rep	2012 Jul	Li S	doi: 10.3892/or.2012.1778
22766503	iASPPsv antagonizes apoptosis induced by chemotherapeutic agents in MCF-7 cells and mouse thymocytes.	Biochem Biophys Res Commun	2012 Aug 3	Wang L	doi: 10.1016/j.bbrc.2012.06.124
23691514	MicroRNA-124 regulates the proliferation of colorectal cancer cells by targeting iASPP.	Biomed Res Int	2013	Liu K	doi: 10.1155/2013/867537
22335888	A specific diplotype defined by PPP1R13L rs1970764, CD3EAP rs967591 and ERCC1 rs11615 and lung cancer risk in a Chinese population.	Lung Cancer	2012 Jun	Yin J	doi: 10.1016/j.lungcan.2012.01.001
18588689	Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP.	BMC Med Genet	2008 Jun 27	Nex BA	doi: 10.1186/1471-2350-9-56.
28870783	19p13.3-GADD45B common variants and 19q13.3-PPP1R13L and 19q13.3-CD3EAP in lung cancer risk among Chinese.	Chem Biol Interact	2017 Nov 1	Hou W	doi: 10.1016/j.cbi.2017.08.018
28418858	The miR-124-p63 feedback loop modulates colorectal cancer growth.	Oncotarget	2017 Apr 25	Liu K	doi: 10.18632/oncotarget.16248.
29022915	Wild-type and mutant p53 differentially modulate miR-124/iASPP feedback following pohotodynamic therapy in human colon cancer cell line.	Cell Death Dis	2017 Oct 12	Liu K	doi: 10.1038/cddis.2017.477.
29750311	MicroRNA-150 inhibits the proliferation and metastasis potential of colorectal cancer cells by targeting iASPP.	Oncol Rep	2018 Jul	Li C	doi: 10.3892/or.2018.6406
29620255	Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment.	Int J Oncol	2018 Jun	Zhang G	doi: 10.3892/ijo.2018.4347

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr19	45380101	3'UTR	novel		0.46
BLCA	chr19	45398274	Missense_Mutation	novel	M15I	0.44
BLCA	chr19	45396590	Silent	rs753059937	L223L	0.57
BLCA	chr19	45382595	Missense_Mutation	novel	E794Q	0.41
BLCA	chr19	45392432	Intron	novel		0.64
BLCA	chr19	45392231	Silent	NA	L488L	0.51
BLCA	chr19	45396391	Missense_Mutation	NA	S253F	0.43
BLCA	chr19	45398309	Missense_Mutation	novel	E4K	0.18
BLCA	chr19	45392303	Silent	rs767546785	P464P	0.12
BLCA	chr19	45396338	Missense_Mutation	NA	R271C	0.29
BLCA	chr19	45396358	Missense_Mutation	rs746396640	S264L	0.08
BLCA	chr19	45385614	Silent	novel	E732E	0.22
BRCA	chr19	45385861	Missense_Mutation	NA	A682T	0.12
BRCA	chr19	45382638	Missense_Mutation	NA	F779L	0.24
CESC	chr19	45398328	5'UTR	novel		0.4
CESC	chr19	45396416	Frame_Shift_Ins	novel	*R245Tfs132**	0.06
CESC	chr19	45396417	Frame_Shift_Ins	novel	*R245Lfs134**	0.05
CESC	chr19	45395412	Intron	novel		0.45
CESC	chr19	45395281	Intron	novel		0.44
CESC	chr19	45398059	Silent	rs190656904	S48S	0.53
CESC	chr19	45380182	3'UTR	novel		0.52
CESC	chr19	45391916	Silent	rs148594569	P593P	0.39
CESC	chr19	45392045	Silent	novel	L550L	0.49
CESC	chr19	45392304	Missense_Mutation	rs752411649	P464L	0.08
COAD	chr19	45385951	Missense_Mutation	NA	D652N	0.28
COAD	chr19	45395649	Missense_Mutation	novel	A381T	0.21
COAD	chr19	45392011	Frame_Shift_Ins	rs780494005	*P562Afs10**	0.56
COAD	chr19	45385711	Missense_Mutation	NA	A700V	0.42
COAD	chr19	45398026	Silent	rs372792420	P59P	0.44
COAD	chr19	45396422	Missense_Mutation	NA	R243C	0.29
COAD	chr19	45380113	3'UTR	novel		0.13
COAD	chr19	45380063	3'UTR	novel		0.34
COAD	chr19	45395472	Frame_Shift_Del	NA	*Q440Sfs10**	0.42
COAD	chr19	45396338	Missense_Mutation	NA	R271C	0.19
COAD	chr19	45380114	3'UTR	novel		0.06
COAD	chr19	45391924	Missense_Mutation	NA	P591S	0.11
COAD	chr19	45396357	Silent	novel	S264S	0.46
COAD	chr19	45395860	Silent	rs560618631	P310P	0.41
ESCA	chr19	45396419	Silent	novel	R244R	0.17
ESCA	chr19	45405048	5'Flank	novel		0.12
GBM	chr19	45392183	Silent	novel	V504V	0.5
HNSC	chr19	45396687	Silent	novel	A190A	0.26
HNSC	chr19	45392187	Missense_Mutation	rs577151019	S503L	0.16
HNSC	chr19	45382638	Silent	novel	F779F	0.44
HNSC	chr19	45397001	Missense_Mutation	novel	R86W	0.29
HNSC	chr19	45397002	Silent	novel	P85P	0.29
HNSC	chr19	45392308	Missense_Mutation	novel	E463Q	0.12
HNSC	chr19	45382618	Missense_Mutation	novel	T786I	0.17
HNSC	chr19	45385958	Splice_Site	novel	X650_splice	0.33
KIRC	chr19	45398276	Missense_Mutation	rs752804434	M15V	0.21
KIRP	chr19	45386141	Missense_Mutation	novel	K619E	0.56
LGG	chr19	45392106	Missense_Mutation	NA	A530V	0.18
LGG	chr19	45382569	Silent	NA	A802A	0.23
LIHC	chr19	45395582	Missense_Mutation	NA	P403R	0.56
LUAD	chr19	45382701	Missense_Mutation	novel	M758I	0.18
LUAD	chr19	45382579	Nonsense_Mutation	NA	W799*	0.17
LUAD	chr19	45382641	Silent	NA	S778S	0.29
LUAD	chr19	45382642	Missense_Mutation	novel	S778C	0.29
LUAD	chr19	45380085	3'UTR	novel		0.11
LUAD	chr19	45396814	Missense_Mutation	novel	G148V	0.44
LUAD	chr19	45396815	Missense_Mutation	novel	G148C	0.44
LUAD	chr19	45392279	Silent	novel	P472P	0.32
LUAD	chr19	45385828	Missense_Mutation	novel	G693S	0.21
LUAD	chr19	45396259	Missense_Mutation	novel	R271L	0.37
LUAD	chr19	45382541	Missense_Mutation	rs763548265	R812W	0.07
LUAD	chr19	45396375	Silent	novel	A258A	0.31
LUAD	chr19	45396394	Missense_Mutation	NA	E252V	0.2
LUAD	chr19	45392160	Missense_Mutation	rs537319636	R512L	0.55
LUAD	chr19	45398018	Missense_Mutation	NA	G62V	0.14
LUSC	chr19	45396418	Missense_Mutation	rs767274852	R244Q	0.39
LUSC	chr19	45396385	Missense_Mutation	novel	L255Q	0.37
LUSC	chr19	45391891	Missense_Mutation	NA	P602A	0.2
LUSC	chr19	45396389	Missense_Mutation	NA	D254N	0.17
LUSC	chr19	45382530	Silent	NA	F815F	0.63
LUSC	chr19	45392002	Missense_Mutation	NA	E565Q	0.32
LUSC	chr19	45392214	Missense_Mutation	novel	Q494R	0.25
LUSC	chr19	45396394	Missense_Mutation	NA	E252V	0.1
LUSC	chr19	45396208	Nonsense_Mutation	NA	W288*	0.56
LUSC	chr19	45385701	Silent	novel	C703C	0.44
LUSC	chr19	45396602	Missense_Mutation	rs777898158	G219W	0.41
LUSC	chr19	45382533	Nonsense_Mutation	novel	Y814*	0.14
LUSC	chr19	45380119	3'UTR	novel		0.16
LUSC	chr19	45380034	3'UTR	novel		0.09
LUSC	chr19	45385831	Missense_Mutation	novel	H692Y	0.15
LUSC	chr19	45396389	Missense_Mutation	novel	D254Y	0.4
LUSC	chr19	45385887	Missense_Mutation	NA	Y673F	0.38
MESO	chr19	45391889	Silent	novel	P602P	0.39
OV	chr19	45396362	Missense_Mutation	novel	P263S	0.26
OV	chr19	45396383	Missense_Mutation	NA	D256Y	0.35
PAAD	chr19	45382683	Silent	novel	Y764Y	0.2
PAAD	chr19	45385668	Silent	rs761004381	Q714Q	0.15
PCPG	chr19	45396982	Missense_Mutation	novel	G92A	0.33
PCPG	chr19	45382683	Silent	novel	Y764Y	0.47
PRAD	chr19	45385617	Silent	rs769470483	F731F	0.15
PRAD	chr19	45391982	Missense_Mutation	rs767692178	E571D	0.17
PRAD	chr19	45385642	Missense_Mutation	NA	T723M	0.25
SARC	chr19	45396409	Missense_Mutation	novel	P247L	0.14
SARC	chr19	45396410	Missense_Mutation	novel	P247S	0.14
SKCM	chr19	45392227	Missense_Mutation	NA	P490S	0.34
SKCM	chr19	45382725	Splice_Region	NA	D750D	0.41
SKCM	chr19	45392086	Missense_Mutation	novel	P537S	0.33
SKCM	chr19	45392087	Silent	novel	P536P	0.34
SKCM	chr19	45392010	Missense_Mutation	rs779760960	P562L	0.77
SKCM	chr19	45392011	Missense_Mutation	rs546903846	P562S	0.76
SKCM	chr19	45391930	Missense_Mutation	NA	P589S	0.39
SKCM	chr19	45395678	Missense_Mutation	NA	P371L	0.67
SKCM	chr19	45382557	Silent	NA	Q806Q	0.28
SKCM	chr19	45392038	Missense_Mutation	rs750806921	R553C	0.43
SKCM	chr19	45396693	Silent	novel	P188P	0.33
SKCM	chr19	45398012	Missense_Mutation	NA	P64L	0.45
SKCM	chr19	45392367	Intron	novel		0.5
SKCM	chr19	45391930	Missense_Mutation	NA	P589S	0.32
SKCM	chr19	45382694	Missense_Mutation	NA	G761R	0.3
SKCM	chr19	45391988	Silent	NA	I569I	0.46
SKCM	chr19	45396209	Missense_Mutation	novel	W288R	0.38
SKCM	chr19	45382725	Splice_Region	NA	D750D	0.18
SKCM	chr19	45392348	Splice_Region	novel		0.24
SKCM	chr19	45392227	Missense_Mutation	NA	P490S	0.35
SKCM	chr19	45395448	Missense_Mutation	NA	P448S	1
STAD	chr19	45397000	Frame_Shift_Ins	novel	*R86Pfs169**	0.5
STAD	chr19	45382617	Silent	NA	T786T	0.4
STAD	chr19	45396620	Missense_Mutation	NA	A213T	0.79
STAD	chr19	45391991	Silent	NA	P568P	0.32
STAD	chr19	45396915	Frame_Shift_Del	novel	*K115Rfs109**	0.36
STAD	chr19	45398039	Missense_Mutation	rs768668757	A55V	0.29
STAD	chr19	45398027	Missense_Mutation	novel	P59L	0.29
STAD	chr19	45396719	Missense_Mutation	NA	R180C	0.38
STAD	chr19	45396375	Silent	novel	A258A	0.08
STAD	chr19	45396421	Missense_Mutation	rs752605602	R243H	0.11
STAD	chr19	45396408	Silent	rs372976271	P247P	0.32
STAD	chr19	45385608	Silent	NA	C734C	0.36
STAD	chr19	45391916	Silent	rs148594569	P593P	0.14
STAD	chr19	45382685	Missense_Mutation	NA	Y764H	0.24
STAD	chr19	45396178	Frame_Shift_Del	NA	*G298Afs77**	0.61
STAD	chr19	45396624	Silent	NA	Y211Y	0.46
STAD	chr19	45392012	Frame_Shift_Del	NA	*P562Rfs75**	0.29
STAD	chr19	45382541	Missense_Mutation	rs763548265	R812W	0.13
STAD	chr19	45398292	Silent	NA	A9A	0.07
STAD	chr19	45392303	Silent	rs767546785	P464P	0.12
THCA	chr19	45386149	Missense_Mutation	NA	S616F	0.28
THCA	chr19	45398288	Missense_Mutation	NA	D11N	0.15
UCEC	chr19	45392049	Missense_Mutation	rs369362396	R549H	0.3
UCEC	chr19	45385622	Missense_Mutation	NA	A730T	0.33
UCEC	chr19	45379983	3'UTR	novel		0.25
UCEC	chr19	45392311	Missense_Mutation	novel	P462S	0.27
UCEC	chr19	45395371	Intron	novel		0.41
UCEC	chr19	45379894	3'UTR	novel		0.26
UCEC	chr19	45398064	Missense_Mutation	novel	E47K	0.43
UCEC	chr19	45385617	Silent	rs769470483	F731F	0.5
UCEC	chr19	45385951	Missense_Mutation	NA	D652N	0.21
UCEC	chr19	45379999	3'UTR	novel		0.23
UCEC	chr19	45392089	Missense_Mutation	NA	P536S	0.32
UCEC	chr19	45395217	Intron	novel		0.34
UCEC	chr19	45397001	Frame_Shift_Del	novel	*R86Gfs138**	0.87
UCEC	chr19	45380054	3'UTR	novel		0.47
UCEC	chr19	45380223	Silent	NA	F818F	0.45
UCEC	chr19	45396902	Missense_Mutation	novel	S119P	0.4
UCEC	chr19	45385661	Missense_Mutation	novel	A717T	0.43
UCEC	chr19	45398329	5'UTR	novel		0.26
UCEC	chr19	45392159	Silent	novel	R512R	0.37
UCEC	chr19	45385577	Missense_Mutation	novel	A745T	0.39
UCEC	chr19	45382544	Missense_Mutation	novel	P811S	0.08
UCEC	chr19	45396983	Missense_Mutation	NA	G92C	0.38
UCEC	chr19	45396231	Silent	NA	S280S	0.2
UCEC	chr19	45382530	Silent	NA	F815F	0.21
UCEC	chr19	45391928	Silent	novel	P589P	0.29
UCEC	chr19	45380046	3'UTR	novel		0.03
UCEC	chr19	45398060	Missense_Mutation	novel	S48L	0.44
UCEC	chr19	45398019	Missense_Mutation	novel	G62R	0.38
UCEC	chr19	45382620	Silent	novel	V785V	0.1
UCEC	chr19	45395434	Splice_Site	novel	X452_splice	0.27
UCEC	chr19	45382529	Missense_Mutation	novel	G816R	0.43
UCEC	chr19	45395306	Intron	novel		0.05
UCEC	chr19	45391907	Missense_Mutation	NA	S596R	0.27
UCEC	chr19	45386050	Missense_Mutation	novel	E649G	0.32
UCEC	chr19	45395359	Intron	novel		0.24
UCEC	chr19	45385837	Missense_Mutation	rs375921349	D690N	0.37
UCEC	chr19	45396376	Missense_Mutation	NA	A258V	0.37
UCEC	chr19	45380013	3'UTR	novel		0.36
UCEC	chr19	45392069	Missense_Mutation	novel	Q542H	0.35
UCEC	chr19	45391890	Missense_Mutation	rs371559540	P602L	0.29

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0712	0.027508
KIRP	DEL	0.0417	0.054726
READ	DEL	0.0667	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1964	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.016	Kaplan-Meier Survival Analysis
COAD	0.007	Kaplan-Meier Survival Analysis
PAAD	0.0059	Kaplan-Meier Survival Analysis
LAML	0.0035	Kaplan-Meier Survival Analysis
LIHC	0.005	Kaplan-Meier Survival Analysis
LGG	0.039	Kaplan-Meier Survival Analysis
LUAD	0.00079	Kaplan-Meier Survival Analysis
UVM	0.00011	Kaplan-Meier Survival Analysis
OV	0.0036	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000104881 (Gene tree)
Gene ID: 10848
Gene Symbol: PPP1R13L
Alias: RAI|IASPP
Full Name: protein phosphatase 1 regulatory subunit 13 like
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 26,716 bases
Position: chr19:45,379,634-45,406,349
Accession: 18838
RBP type: non-canonical RBP
Summary: IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000591986	PPP1R13L-207	648	-	ENSP00000466939	29 (aa)	-	K7ENG6
ENST00000589858	PPP1R13L-206	610	-	-	- (aa)	-	-
ENST00000593226	PPP1R13L-209	525	-	ENSP00000466730	128 (aa)	-	K7EN03
ENST00000592134	PPP1R13L-208	392	-	ENSP00000467471	60 (aa)	-	K7EPP1
ENST00000360957	PPP1R13L-201	3104	-	ENSP00000354218	828 (aa)	-	Q8WUF5
ENST00000585905	PPP1R13L-203	2176	-	-	- (aa)	-	-
ENST00000587270	PPP1R13L-204	2512	-	-	- (aa)	-	-
ENST00000589371	PPP1R13L-205	355	-	ENSP00000466555	90 (aa)	-	K7EML6
ENST00000418234	PPP1R13L-202	3118	XM_017026177	ENSP00000403902	828 (aa)	XP_016881666	Q8WUF5

Gene Model

Click here to download ENSG00000104881's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000104881's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0003215	cardiac right ventricle morphogenesis	-	IEA	Process
GO:0003229	ventricular cardiac muscle tissue development	-	IEA	Process
GO:0003714	transcription corepressor activity	10336463.	TAS	Function
GO:0005515	protein binding	17906639.18275817.18985028.21513714.21998301.22321011.23623661.24855949.26496610.27173435.28330616.	IPI	Function
GO:0005634	nucleus	10336463.	TAS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006351	transcription, DNA-templated	-	IEA	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0008134	transcription factor binding	-	IEA	Function
GO:0009791	post-embryonic development	-	IEA	Process
GO:0030054	cell junction	-	IDA	Component
GO:0031076	embryonic camera-type eye development	-	IEA	Process
GO:0035264	multicellular organism growth	-	IEA	Process
GO:0042633	hair cycle	-	IEA	Process
GO:0042802	identical protein binding	18275817.23623661.	IPI	Function
GO:0045171	intercellular bridge	-	IDA	Component
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0045597	positive regulation of cell differentiation	-	IEA	Process
GO:0048871	multicellular organismal homeostasis	-	IEA	Process
GO:0060048	cardiac muscle contraction	-	IEA	Process
GO:1901796	regulation of signal transduction by p53 class mediator	-	TAS	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.