EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27129219	HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.	J Biol Chem	2016 Jun 10	Chen Y	doi: 10.1074/jbc.M116.714147
16179914	Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells.	Leukemia	2005 Nov	Yao CJ	-
26660958	All Trans-Retinoic Acid Mediates MED28/HMG Box-Containing Protein 1 (HBP1)/β-Catenin Signaling in Human Colorectal Cancer Cells.	J Cell Physiol	2016 Aug	Lee MF	doi: 10.1002/jcp.25285
20505989	miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1.	Breast Cancer Res Treat	2011 Apr	Li H	doi: 10.1007/s10549-010-0954-4
17616670	Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.	Cancer Res	2007 Jul 1	Paulson KE	-
20383199	Macrophage migration inhibitory factor is a direct target of HBP1-mediated transcriptional repression that is overexpressed in prostate cancer.	Oncogene	2010 May 27	Chen YC	doi: 10.1038/onc.2010.97
16495219	Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1.	J Biol Chem	2006 Apr 21	Kim J	-
26942107	Transcription Factor HBP1 Enhances Radiosensitivity by Inducing Apoptosis in Prostate Cancer Cell Lines.	Anal Cell Pathol (Amst)	2016	Chen Y	doi: 10.1155/2016/7015659
24895061	HBP1 promoter methylation augments the oncogenic β-catenin to correlate with prognosis in NSCLC.	J Cell Mol Med	2014 Sep	Tseng RC	doi: 10.1111/jcmm.12318
16966377	The HBP1 transcriptional repressor participates in RAS-induced premature senescence.	Mol Cell Biol	2006 Nov	Zhang X	-
11500377	Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1.	EMBO J	2001 Aug 15	Sampson EM	-
28099936	Transcription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer.	Oncotarget	2017 Feb 28	Chan CY	doi: 10.18632/oncotarget.14653.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr7	107201446	3'UTR	novel		0.34
BLCA	chr7	107190285	Missense_Mutation	novel	F345L	0.19
BLCA	chr7	107201500	3'UTR	novel		0.77
BLCA	chr7	107201511	3'UTR	novel		0.38
BLCA	chr7	107185878	Missense_Mutation	rs762848519	S159L	0.32
BLCA	chr7	107201479	3'UTR	novel		0.38
BRCA	chr7	107200197	Missense_Mutation	NA	M475V	0.31
BRCA	chr7	107189364	Silent	novel	L280L	0.05
BRCA	chr7	107182490	Missense_Mutation	novel	S96L	0.15
BRCA	chr7	107179880	Splice_Region	novel		0.05
BRCA	chr7	107201226	Intron	novel		0.44
BRCA	chr7	107200162	Missense_Mutation	NA	A463G	0.26
BRCA	chr7	107189289	Splice_Region	novel		0.34
BRCA	chr7	107201439	3'UTR	novel		0.06
BRCA	chr7	107196021	Frame_Shift_Del	NA	*N420Tfs7**	0.12
BRCA	chr7	107201206	Intron	novel		0.5
BRCA	chr7	107190268	Missense_Mutation	NA	P340T	0.2
CESC	chr7	107190198	Missense_Mutation	novel	L316F	0.32	AXH
COAD	chr7	107200258	Missense_Mutation	NA	K495T	0.4
COAD	chr7	107201362	Intron	NA		0.2
COAD	chr7	107186383	Missense_Mutation	NA	G188D	0.31
COAD	chr7	107195929	Missense_Mutation	novel	G388D	0.05
COAD	chr7	107201508	3'UTR	novel		0.34
COAD	chr7	107182558	Missense_Mutation	NA	T119A	0.28
COAD	chr7	107186466	Nonsense_Mutation	novel	L216*	0.06	AXH
DLBC	chr7	107201246	Intron	novel		0.29
ESCA	chr7	107196146	Missense_Mutation	novel	D460E	0.23
ESCA	chr7	107196148	Missense_Mutation	novel	N461S	0.24
ESCA	chr7	107186587	Missense_Mutation	rs768445935	H224L	0.37	AXH
ESCA	chr7	107182573	Missense_Mutation	novel	P124S	0.11
ESCA	chr7	107189302	Missense_Mutation	novel	S259F	0.1	AXH
ESCA	chr7	107182453	Missense_Mutation	novel	Q84K	0.34
ESCA	chr7	107168961	5'Flank	novel		0.24
GBM	chr7	107185937	Missense_Mutation	rs769903941	E179K	0.46
GBM	chr7	107196227	Intron	novel		0.44
GBM	chr7	107201542	3'UTR	novel		0.21
GBM	chr7	107190199	Missense_Mutation	novel	T317P	0.04	AXH
GBM	chr7	107186369	Missense_Mutation	novel	S183R	0.05
GBM	chr7	107189348	Silent	NA	G274G	0.27
HNSC	chr7	107185819	Silent	novel	I139I	0.11
HNSC	chr7	107186443	Missense_Mutation	novel	P208R	0.46
HNSC	chr7	107182500	Silent	novel	P99P	0.41
HNSC	chr7	107185806	Missense_Mutation	novel	S135C	0.4
HNSC	chr7	107185854	Missense_Mutation	rs151293151	R151H	0.38
HNSC	chr7	107195883	Missense_Mutation	novel	M373V	0.29
KIRP	chr7	107189349	Missense_Mutation	rs754955216	E275K	0.48	AXH
LGG	chr7	107196126	Missense_Mutation	NA	Q454E	0.42
LGG	chr7	107200350	Intron	novel		0.36
LIHC	chr7	107201144	Intron	novel		0.42
LIHC	chr7	107180019	Silent	rs772877520	P42P	0.26
LIHC	chr7	107182441	Missense_Mutation	novel	D80N	0.09
LIHC	chr7	107200223	Silent	rs538604670	Y483Y	0.23
LUAD	chr7	107186415	Missense_Mutation	NA	D199N	0.28
LUAD	chr7	107200324	Intron	novel		0.39
LUAD	chr7	107200283	Missense_Mutation	NA	K503N	0.15
LUAD	chr7	107201418	Nonsense_Mutation	novel	S511*	0.15
LUAD	chr7	107201374	Intron	novel		0.17
LUAD	chr7	107185909	Silent	rs372297264	H169H	0.04
LUSC	chr7	107200351	Intron	novel		0.33
LUSC	chr7	107195991	Missense_Mutation	NA	S409T	0.38
LUSC	chr7	107195852	Missense_Mutation	NA	M362I	0.29
LUSC	chr7	107190257	Missense_Mutation	NA	P336L	0.41	AXH
PAAD	chr7	107179923	Missense_Mutation	rs779971042	M10I	0.07
READ	chr7	107190289	Missense_Mutation	NA	D347Y	0.18
READ	chr7	107182467	Missense_Mutation	novel	R88S	0.35
READ	chr7	107190271	Missense_Mutation	rs753601120	D341N	0.41
SKCM	chr7	107190268	Missense_Mutation	NA	P340T	0.52
SKCM	chr7	107201307	Intron	novel		0.32
SKCM	chr7	107195881	Missense_Mutation	NA	S372N	0.45
SKCM	chr7	107196136	Missense_Mutation	novel	P457L	0.19
SKCM	chr7	107200270	Missense_Mutation	NA	P499L	0.13
SKCM	chr7	107185875	Missense_Mutation	NA	S158F	0.28
SKCM	chr7	107182554	Silent	rs760620645	I117I	0.08
STAD	chr7	107196063	Frame_Shift_Del	novel	*K433Sfs6**	0.22
STAD	chr7	107200355	Intron	novel		0.13
STAD	chr7	107179929	Silent	NA	N12N	0.1
STAD	chr7	107189406	Missense_Mutation	NA	V294L	0.22	AXH
STAD	chr7	107186609	Nonsense_Mutation	NA	W231*	0.2	AXH
UCEC	chr7	107196006	Missense_Mutation	novel	Y414H	0.38
UCEC	chr7	107190244	Missense_Mutation	novel	D332N	0.41	AXH
UCEC	chr7	107190210	Silent	novel	Q320Q	0.06
UCEC	chr7	107195889	Missense_Mutation	novel	R375C	0.54
UCEC	chr7	107195889	Missense_Mutation	novel	R375C	0.43
UCEC	chr7	107201485	3'UTR	novel		0.45
UCEC	chr7	107200316	Intron	novel		0.23
UCEC	chr7	107201402	Intron	novel		0.15
UCEC	chr7	107201283	Intron	novel		0.47
UCEC	chr7	107200508	Intron	novel		0.36
UCEC	chr7	107182522	Nonsense_Mutation	NA	E107*	0.26
UCEC	chr7	107185878	Missense_Mutation	rs762848519	S159L	0.15
UCEC	chr7	107200331	Intron	novel		0.12
UCEC	chr7	107179884	5'UTR	novel		0.14
UCEC	chr7	107186658	Missense_Mutation	novel	D248Y	0.23	AXH
UCEC	chr7	107190270	Silent	rs777440206	P340P	0.29
UCEC	chr7	107190187	Missense_Mutation	novel	Y313D	0.31	AXH
UCEC	chr7	107196233	Intron	novel		0.39
UCEC	chr7	107200291	Missense_Mutation	novel	R506I	0.37
UCEC	chr7	107200407	Intron	novel		0.55
UCEC	chr7	107180011	Missense_Mutation	novel	N40Y	0.18
UCEC	chr7	107168997	5'Flank	novel		0.32
UCEC	chr7	107186575	Missense_Mutation	rs746761056	R220Q	0.42	AXH
UCEC	chr7	107201201	Intron	novel		0.3
UCEC	chr7	107190281	Missense_Mutation	novel	N344T	0.08
UCEC	chr7	107189334	Missense_Mutation	NA	S270C	0.41	AXH
UCEC	chr7	107169054	5'UTR	novel		0.42
UCEC	chr7	107190281	Missense_Mutation	novel	N344T	0.43
UCEC	chr7	107201447	3'UTR	novel		0.55
UCEC	chr7	107186645	Missense_Mutation	NA	C243W	0.44	AXH
UCEC	chr7	107185879	Silent	rs573245535	S159S	0.38
UCEC	chr7	107196238	Intron	novel		0.29
UCEC	chr7	107190271	Missense_Mutation	novel	D341Y	0.15
UCEC	chr7	107189409	Nonsense_Mutation	novel	E295*	0.49	AXH
UCEC	chr7	107195896	Missense_Mutation	novel	R377H	0.14
UCEC	chr7	107186575	Missense_Mutation	rs746761056	R220Q	0.44	AXH
UCEC	chr7	107189352	Missense_Mutation	novel	S276P	0.06	AXH
UCEC	chr7	107169086	5'UTR	novel		0.44
UCEC	chr7	107180052	Silent	novel	H53H	0.32
UCEC	chr7	107182542	Missense_Mutation	novel	E113D	0.28
UCEC	chr7	107195939	Silent	novel	F391F	0.19
UCEC	chr7	107196137	Nonsense_Mutation	novel	G458*	0.1
UCEC	chr7	107186599	Missense_Mutation	novel	N228I	0.39	AXH
UCEC	chr7	107186441	Nonsense_Mutation	novel	W207*	0.35
UCEC	chr7	107200447	Intron	novel		0.48
UCEC	chr7	107189421	Missense_Mutation	novel	D299N	0.07	AXH
UCEC	chr7	107169020	5'UTR	novel		0.28
UCEC	chr7	107200162	Missense_Mutation	novel	A463V	0.31
UCS	chr7	107186457	Missense_Mutation	novel	H213Y	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.0778	0.12261
DLBC	AMP	0.2917	0.13215
LGG	AMP	0.3041	1.5525e-07
LIHC	DEL	0.0595	0.24831
PAAD	DEL	0.0489	0.049388
PRAD	AMP	0.1362	0.012709
TGCT	AMP	0.62	0.035574
THCA	DEL	0.002	0.27619
UCS	DEL	0.2321	0.10142

Survival Analysis

Cancer	P-value	Q-value
MESO	0.017	Kaplan-Meier Survival Analysis
HNSC	0.029	Kaplan-Meier Survival Analysis
SKCM	0.015	Kaplan-Meier Survival Analysis
PAAD	0.0078	Kaplan-Meier Survival Analysis
LAML	0.0015	Kaplan-Meier Survival Analysis
GBM	0.03	Kaplan-Meier Survival Analysis
LGG	0.0015	Kaplan-Meier Survival Analysis
LUAD	0.006	Kaplan-Meier Survival Analysis
OV	0.019	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000105856 (Gene tree)
Gene ID: 26959
Gene Symbol: HBP1
Alias: -
Full Name: HMG-box transcription factor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 33,569 bases
Position: chr7:107,168,961-107,202,529
Accession: 23200
RBP type: canonical RBP
Summary: HBP1 (HMG-Box Transcription Factor 1) is a Protein Coding gene. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription and C-MYC pathway. Gene Ontology (GO) annotations related to this gene include RNA binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000418017	AXH	PF08517.12	3e-34	1	1
ENSP00000222574	AXH	PF08517.12	3.7e-34	1	1
ENSP00000418738	AXH	PF08517.12	3.7e-34	1	1
ENSP00000420500	AXH	PF08517.12	3.7e-34	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
2680601	Multiplicity of the DNA-binding protein HBP-1 specific to the conserved hexameric sequence ACGTCA in various plant gene promoters.	FEBS Lett	1989 Oct 9	Mikami K	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000463790	HBP1-204	433	-	ENSP00000419143	85 (aa)	-	H7C574
ENST00000222574	HBP1-201	2829	XM_024446714	ENSP00000222574	514 (aa)	XP_024302482	O60381
ENST00000468410	HBP1-208	2704	XM_017011967	ENSP00000420500	514 (aa)	XP_016867456	O60381
ENST00000463202	HBP1-203	2646	-	-	- (aa)	-	-
ENST00000464009	HBP1-205	478	-	ENSP00000420137	124 (aa)	-	C9JQU7
ENST00000479011	HBP1-210	601	-	ENSP00000417927	111 (aa)	-	C9J5U3
ENST00000497535	HBP1-213	702	-	ENSP00000417631	108 (aa)	-	C9J8V6
ENST00000607681	HBP1-215	476	-	ENSP00000475809	154 (aa)	-	U3KQE5
ENST00000498408	HBP1-214	2332	-	ENSP00000418017	454 (aa)	-	H7C4S2
ENST00000485846	HBP1-212	2420	XM_005250266	ENSP00000418738	514 (aa)	XP_005250323	O60381
ENST00000478930	HBP1-209	563	-	ENSP00000418022	70 (aa)	-	C9JAW1
ENST00000483809	HBP1-211	582	-	-	- (aa)	-	-
ENST00000468401	HBP1-207	573	-	ENSP00000420281	28 (aa)	-	C9JPK6
ENST00000468116	HBP1-206	579	-	-	- (aa)	-	-
ENST00000461963	HBP1-202	581	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000105856's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000105856's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000105856	HBP1	96	72.297	ENSAPOG00000015816	hbp1	99	62.986	Acanthochromis_polyacanthus
ENSG00000105856	HBP1	100	100.000	ENSAMEG00000013492	HBP1	99	96.304	Ailuropoda_melanoleuca
ENSG00000105856	HBP1	97	66.887	ENSACIG00000019093	-	96	54.776	Amphilophus_citrinellus
ENSG00000105856	HBP1	99	70.588	ENSACIG00000018873	hbp1	99	59.693	Amphilophus_citrinellus
ENSG00000105856	HBP1	97	59.119	ENSAOCG00000001429	-	99	53.458	Amphiprion_ocellaris
ENSG00000105856	HBP1	96	72.297	ENSAOCG00000010889	hbp1	99	62.577	Amphiprion_ocellaris
ENSG00000105856	HBP1	97	58.491	ENSAPEG00000022589	-	99	53.084	Amphiprion_percula
ENSG00000105856	HBP1	96	72.297	ENSAPEG00000002330	hbp1	99	62.577	Amphiprion_percula
ENSG00000105856	HBP1	97	63.333	ENSATEG00000003902	-	97	57.172	Anabas_testudineus
ENSG00000105856	HBP1	96	72.297	ENSATEG00000016411	hbp1	99	62.933	Anabas_testudineus
ENSG00000105856	HBP1	100	92.857	ENSAPLG00000007110	HBP1	100	84.038	Anas_platyrhynchos
ENSG00000105856	HBP1	100	92.857	ENSACAG00000015023	HBP1	99	81.660	Anolis_carolinensis
ENSG00000105856	HBP1	100	100.000	ENSANAG00000022302	HBP1	100	99.222	Aotus_nancymaae
ENSG00000105856	HBP1	97	65.132	ENSACLG00000003606	HBP1	99	53.296	Astatotilapia_calliptera
ENSG00000105856	HBP1	96	72.297	ENSACLG00000004758	hbp1	95	62.577	Astatotilapia_calliptera
ENSG00000105856	HBP1	100	63.900	ENSAMXG00000017678	hbp1	97	65.835	Astyanax_mexicanus
ENSG00000105856	HBP1	100	94.358	ENSBTAG00000005524	HBP1	98	93.774	Bos_taurus
ENSG00000105856	HBP1	100	100.000	ENSCJAG00000016260	HBP1	99	99.222	Callithrix_jacchus
ENSG00000105856	HBP1	100	100.000	ENSCAFG00000003939	HBP1	98	96.498	Canis_familiaris
ENSG00000105856	HBP1	100	100.000	ENSCAFG00020023119	HBP1	98	96.498	Canis_lupus_dingo
ENSG00000105856	HBP1	100	94.358	ENSCHIG00000024405	HBP1	100	93.774	Capra_hircus
ENSG00000105856	HBP1	100	100.000	ENSTSYG00000010057	HBP1	100	98.447	Carlito_syrichta
ENSG00000105856	HBP1	100	96.429	ENSCAPG00000017460	HBP1	99	93.774	Cavia_aperea
ENSG00000105856	HBP1	100	96.429	ENSCPOG00000002375	HBP1	98	94.358	Cavia_porcellus
ENSG00000105856	HBP1	100	100.000	ENSCCAG00000026359	HBP1	100	99.222	Cebus_capucinus
ENSG00000105856	HBP1	100	100.000	ENSCATG00000021910	HBP1	100	99.416	Cercocebus_atys
ENSG00000105856	HBP1	100	97.276	ENSCLAG00000005170	HBP1	100	97.276	Chinchilla_lanigera
ENSG00000105856	HBP1	100	99.222	ENSCSAG00000011395	HBP1	98	99.222	Chlorocebus_sabaeus
ENSG00000105856	HBP1	100	96.429	ENSCHOG00000006820	HBP1	70	100.000	Choloepus_hoffmanni
ENSG00000105856	HBP1	100	89.286	ENSCPBG00000000954	HBP1	98	85.549	Chrysemys_picta_bellii
ENSG00000105856	HBP1	100	100.000	ENSCANG00000022804	HBP1	100	99.416	Colobus_angolensis_palliatus
ENSG00000105856	HBP1	100	100.000	ENSCGRG00001014437	Hbp1	98	93.592	Cricetulus_griseus_chok1gshd
ENSG00000105856	HBP1	100	100.000	ENSCGRG00000013859	Hbp1	98	93.592	Cricetulus_griseus_crigri
ENSG00000105856	HBP1	96	70.270	ENSCSEG00000003373	hbp1	99	63.061	Cynoglossus_semilaevis
ENSG00000105856	HBP1	96	72.973	ENSCVAG00000008930	hbp1	99	61.963	Cyprinodon_variegatus
ENSG00000105856	HBP1	97	62.500	ENSCVAG00000008501	-	99	53.537	Cyprinodon_variegatus
ENSG00000105856	HBP1	96	71.622	ENSDARG00000028517	hbp1	100	63.689	Danio_rerio
ENSG00000105856	HBP1	100	100.000	ENSDNOG00000004405	HBP1	95	97.471	Dasypus_novemcinctus
ENSG00000105856	HBP1	100	97.143	ENSDORG00000010576	Hbp1	97	96.338	Dipodomys_ordii
ENSG00000105856	HBP1	100	96.429	ENSETEG00000018542	HBP1	100	86.576	Echinops_telfairi
ENSG00000105856	HBP1	98	57.895	ENSEBUG00000016475	hbp1	83	45.691	Eptatretus_burgeri
ENSG00000105856	HBP1	100	100.000	ENSEASG00005017469	HBP1	91	97.082	Equus_asinus_asinus
ENSG00000105856	HBP1	100	100.000	ENSECAG00000020969	HBP1	99	97.276	Equus_caballus
ENSG00000105856	HBP1	97	67.763	ENSELUG00000006967	hbp1	99	61.538	Esox_lucius
ENSG00000105856	HBP1	97	67.114	ENSELUG00000017031	-	92	56.947	Esox_lucius
ENSG00000105856	HBP1	100	97.143	ENSFCAG00000005858	HBP1	91	94.747	Felis_catus
ENSG00000105856	HBP1	100	92.857	ENSFALG00000010259	HBP1	98	82.885	Ficedula_albicollis
ENSG00000105856	HBP1	100	97.143	ENSFDAG00000007897	HBP1	98	96.304	Fukomys_damarensis
ENSG00000105856	HBP1	97	65.563	ENSFHEG00000014389	-	99	53.626	Fundulus_heteroclitus
ENSG00000105856	HBP1	96	71.622	ENSFHEG00000008222	hbp1	99	62.168	Fundulus_heteroclitus
ENSG00000105856	HBP1	96	71.622	ENSGMOG00000013782	hbp1	99	60.861	Gadus_morhua
ENSG00000105856	HBP1	55	68.085	ENSGMOG00000014613	-	98	59.756	Gadus_morhua
ENSG00000105856	HBP1	100	92.857	ENSGALG00000008050	HBP1	98	82.692	Gallus_gallus
ENSG00000105856	HBP1	97	64.667	ENSGAFG00000004651	-	99	54.493	Gambusia_affinis
ENSG00000105856	HBP1	96	72.297	ENSGAFG00000021976	hbp1	99	62.781	Gambusia_affinis
ENSG00000105856	HBP1	96	62.914	ENSGACG00000019192	-	95	53.753	Gasterosteus_aculeatus
ENSG00000105856	HBP1	96	71.053	ENSGACG00000010054	hbp1	99	61.663	Gasterosteus_aculeatus
ENSG00000105856	HBP1	100	89.286	ENSGAGG00000023042	HBP1	98	85.164	Gopherus_agassizii
ENSG00000105856	HBP1	100	100.000	ENSGGOG00000007788	HBP1	100	99.805	Gorilla_gorilla
ENSG00000105856	HBP1	96	72.297	ENSHBUG00000004967	hbp1	98	61.554	Haplochromis_burtoni
ENSG00000105856	HBP1	97	65.563	ENSHBUG00000016198	-	99	53.672	Haplochromis_burtoni
ENSG00000105856	HBP1	100	100.000	ENSHGLG00000019188	HBP1	98	96.498	Heterocephalus_glaber_female
ENSG00000105856	HBP1	100	100.000	ENSHGLG00100001912	HBP1	98	96.498	Heterocephalus_glaber_male
ENSG00000105856	HBP1	100	80.000	ENSHGLG00100014672	-	100	73.346	Heterocephalus_glaber_male
ENSG00000105856	HBP1	96	68.919	ENSHCOG00000011877	hbp1	99	59.714	Hippocampus_comes
ENSG00000105856	HBP1	95	60.544	ENSHCOG00000010740	-	87	52.128	Hippocampus_comes
ENSG00000105856	HBP1	96	73.649	ENSIPUG00000023044	hbp1	97	65.184	Ictalurus_punctatus
ENSG00000105856	HBP1	100	100.000	ENSSTOG00000013846	HBP1	98	97.471	Ictidomys_tridecemlineatus
ENSG00000105856	HBP1	100	100.000	ENSJJAG00000015341	Hbp1	98	97.471	Jaculus_jaculus
ENSG00000105856	HBP1	96	59.732	ENSKMAG00000000266	-	96	53.659	Kryptolebias_marmoratus
ENSG00000105856	HBP1	96	74.172	ENSKMAG00000003132	hbp1	99	63.599	Kryptolebias_marmoratus
ENSG00000105856	HBP1	97	62.000	ENSLBEG00000023959	-	99	54.702	Labrus_bergylta
ENSG00000105856	HBP1	97	72.483	ENSLBEG00000012078	hbp1	99	62.245	Labrus_bergylta
ENSG00000105856	HBP1	97	78.289	ENSLACG00000009119	HBP1	97	73.745	Latimeria_chalumnae
ENSG00000105856	HBP1	96	77.027	ENSLOCG00000015822	hbp1	98	70.930	Lepisosteus_oculatus
ENSG00000105856	HBP1	100	100.000	ENSLAFG00000005317	HBP1	100	94.951	Loxodonta_africana
ENSG00000105856	HBP1	100	100.000	ENSMFAG00000030375	HBP1	100	99.416	Macaca_fascicularis
ENSG00000105856	HBP1	100	100.000	ENSMMUG00000015409	HBP1	98	99.411	Macaca_mulatta
ENSG00000105856	HBP1	100	100.000	ENSMNEG00000037516	HBP1	100	93.385	Macaca_nemestrina
ENSG00000105856	HBP1	100	100.000	ENSMLEG00000031993	HBP1	100	99.222	Mandrillus_leucophaeus
ENSG00000105856	HBP1	96	73.649	ENSMAMG00000023227	hbp1	99	63.525	Mastacembelus_armatus
ENSG00000105856	HBP1	97	67.333	ENSMAMG00000023588	-	91	57.407	Mastacembelus_armatus
ENSG00000105856	HBP1	97	72.483	ENSMZEG00005005999	hbp1	79	62.062	Maylandia_zebra
ENSG00000105856	HBP1	97	65.132	ENSMZEG00005015065	HBP1	99	53.296	Maylandia_zebra
ENSG00000105856	HBP1	100	92.857	ENSMGAG00000006880	HBP1	98	82.308	Meleagris_gallopavo
ENSG00000105856	HBP1	100	96.429	ENSMAUG00000011449	Hbp1	98	92.816	Mesocricetus_auratus
ENSG00000105856	HBP1	99	99.346	ENSMICG00000012858	HBP1	100	98.249	Microcebus_murinus
ENSG00000105856	HBP1	100	100.000	ENSMOCG00000019227	Hbp1	98	93.981	Microtus_ochrogaster
ENSG00000105856	HBP1	96	71.622	ENSMMOG00000012207	hbp1	98	59.528	Mola_mola
ENSG00000105856	HBP1	97	64.000	ENSMMOG00000010239	-	98	54.415	Mola_mola
ENSG00000105856	HBP1	100	96.429	ENSMODG00000016376	HBP1	89	90.329	Monodelphis_domestica
ENSG00000105856	HBP1	97	62.416	ENSMALG00000010834	-	95	52.664	Monopterus_albus
ENSG00000105856	HBP1	96	72.297	ENSMALG00000009884	hbp1	99	62.933	Monopterus_albus
ENSG00000105856	HBP1	100	97.143	MGP_CAROLIEiJ_G0017683	Hbp1	98	94.767	Mus_caroli
ENSG00000105856	HBP1	100	97.143	ENSMUSG00000002996	Hbp1	98	94.767	Mus_musculus
ENSG00000105856	HBP1	100	100.000	MGP_PahariEiJ_G0029441	Hbp1	98	95.146	Mus_pahari
ENSG00000105856	HBP1	100	97.143	MGP_SPRETEiJ_G0018525	Hbp1	100	94.181	Mus_spretus
ENSG00000105856	HBP1	100	100.000	ENSMPUG00000018249	HBP1	98	97.276	Mustela_putorius_furo
ENSG00000105856	HBP1	100	100.000	ENSMLUG00000012425	HBP1	98	97.860	Myotis_lucifugus
ENSG00000105856	HBP1	100	100.000	ENSNGAG00000023485	Hbp1	98	96.498	Nannospalax_galili
ENSG00000105856	HBP1	96	72.297	ENSNBRG00000001405	hbp1	98	61.554	Neolamprologus_brichardi
ENSG00000105856	HBP1	97	65.132	ENSNBRG00000017820	-	99	54.049	Neolamprologus_brichardi
ENSG00000105856	HBP1	100	100.000	ENSNLEG00000008761	HBP1	100	99.416	Nomascus_leucogenys
ENSG00000105856	HBP1	100	96.429	ENSMEUG00000011116	HBP1	90	87.500	Notamacropus_eugenii
ENSG00000105856	HBP1	100	100.000	ENSOPRG00000005315	HBP1	70	100.000	Ochotona_princeps
ENSG00000105856	HBP1	100	92.857	ENSODEG00000010517	-	99	68.811	Octodon_degus
ENSG00000105856	HBP1	100	98.571	ENSODEG00000001327	-	98	97.665	Octodon_degus
ENSG00000105856	HBP1	86	87.097	ENSODEG00000000482	-	98	72.837	Octodon_degus
ENSG00000105856	HBP1	96	71.622	ENSONIG00000008523	hbp1	99	62.577	Oreochromis_niloticus
ENSG00000105856	HBP1	97	64.935	ENSONIG00000011868	-	99	54.826	Oreochromis_niloticus
ENSG00000105856	HBP1	100	100.000	ENSOANG00000003174	HBP1	100	83.977	Ornithorhynchus_anatinus
ENSG00000105856	HBP1	100	100.000	ENSOCUG00000012758	HBP1	100	95.331	Oryctolagus_cuniculus
ENSG00000105856	HBP1	96	72.297	ENSORLG00000004396	hbp1	99	61.350	Oryzias_latipes
ENSG00000105856	HBP1	97	62.500	ENSORLG00000009474	-	99	53.831	Oryzias_latipes
ENSG00000105856	HBP1	97	72.483	ENSORLG00020000370	hbp1	99	61.350	Oryzias_latipes_hni
ENSG00000105856	HBP1	97	63.158	ENSORLG00020004269	-	99	54.023	Oryzias_latipes_hni
ENSG00000105856	HBP1	96	72.297	ENSORLG00015006557	hbp1	99	61.350	Oryzias_latipes_hsok
ENSG00000105856	HBP1	96	72.297	ENSOMEG00000012837	hbp1	99	62.168	Oryzias_melastigma
ENSG00000105856	HBP1	97	65.132	ENSOMEG00000013045	-	98	54.023	Oryzias_melastigma
ENSG00000105856	HBP1	100	97.665	ENSOGAG00000013102	HBP1	100	97.665	Otolemur_garnettii
ENSG00000105856	HBP1	100	94.163	ENSOARG00000005055	HBP1	98	93.580	Ovis_aries
ENSG00000105856	HBP1	100	100.000	ENSPPAG00000042116	HBP1	100	100.000	Pan_paniscus
ENSG00000105856	HBP1	100	97.143	ENSPPRG00000007240	HBP1	100	94.747	Panthera_pardus
ENSG00000105856	HBP1	100	97.143	ENSPTIG00000002734	HBP1	100	92.412	Panthera_tigris_altaica
ENSG00000105856	HBP1	100	100.000	ENSPTRG00000019575	HBP1	100	100.000	Pan_troglodytes
ENSG00000105856	HBP1	100	100.000	ENSPANG00000024385	HBP1	100	99.416	Papio_anubis
ENSG00000105856	HBP1	96	64.474	ENSPKIG00000016269	HBP1	98	54.951	Paramormyrops_kingsleyae
ENSG00000105856	HBP1	97	71.053	ENSPKIG00000016967	hbp1	98	63.301	Paramormyrops_kingsleyae
ENSG00000105856	HBP1	100	89.286	ENSPSIG00000012478	HBP1	92	84.586	Pelodiscus_sinensis
ENSG00000105856	HBP1	99	58.553	ENSPMGG00000008031	-	93	51.760	Periophthalmus_magnuspinnatus
ENSG00000105856	HBP1	96	72.848	ENSPMGG00000005789	hbp1	95	61.663	Periophthalmus_magnuspinnatus
ENSG00000105856	HBP1	100	97.143	ENSPEMG00000014801	Hbp1	98	94.369	Peromyscus_maniculatus_bairdii
ENSG00000105856	HBP1	97	61.333	ENSPMAG00000002631	hbp1	99	49.038	Petromyzon_marinus
ENSG00000105856	HBP1	100	96.429	ENSPCIG00000004275	HBP1	89	90.716	Phascolarctos_cinereus
ENSG00000105856	HBP1	96	72.973	ENSPFOG00000003951	hbp1	99	62.986	Poecilia_formosa
ENSG00000105856	HBP1	97	65.333	ENSPFOG00000012271	-	96	53.640	Poecilia_formosa
ENSG00000105856	HBP1	97	66.443	ENSPLAG00000012669	-	98	56.846	Poecilia_latipinna
ENSG00000105856	HBP1	96	72.973	ENSPLAG00000003142	hbp1	99	62.986	Poecilia_latipinna
ENSG00000105856	HBP1	97	65.333	ENSPMEG00000015095	-	99	53.831	Poecilia_mexicana
ENSG00000105856	HBP1	96	72.973	ENSPMEG00000003800	hbp1	99	62.986	Poecilia_mexicana
ENSG00000105856	HBP1	97	64.430	ENSPREG00000015242	-	84	62.626	Poecilia_reticulata
ENSG00000105856	HBP1	96	72.973	ENSPREG00000004000	hbp1	99	62.781	Poecilia_reticulata
ENSG00000105856	HBP1	100	100.000	ENSPPYG00000017898	HBP1	98	99.805	Pongo_abelii
ENSG00000105856	HBP1	100	100.000	ENSPCAG00000014060	HBP1	100	93.713	Procavia_capensis
ENSG00000105856	HBP1	100	96.429	ENSPCOG00000015370	HBP1	100	99.475	Propithecus_coquereli
ENSG00000105856	HBP1	100	100.000	ENSPVAG00000014543	HBP1	100	97.276	Pteropus_vampyrus
ENSG00000105856	HBP1	97	72.483	ENSPNYG00000001079	hbp1	95	62.577	Pundamilia_nyererei
ENSG00000105856	HBP1	97	65.132	ENSPNYG00000015063	HBP1	99	54.237	Pundamilia_nyererei
ENSG00000105856	HBP1	96	73.649	ENSPNAG00000029977	hbp1	97	66.603	Pygocentrus_nattereri
ENSG00000105856	HBP1	100	93.010	ENSRNOG00000008927	Hbp1	98	92.621	Rattus_norvegicus
ENSG00000105856	HBP1	100	100.000	ENSRBIG00000042410	HBP1	100	80.777	Rhinopithecus_bieti
ENSG00000105856	HBP1	100	100.000	ENSRROG00000036622	HBP1	100	99.222	Rhinopithecus_roxellana
ENSG00000105856	HBP1	100	100.000	ENSSBOG00000023603	HBP1	100	99.222	Saimiri_boliviensis_boliviensis
ENSG00000105856	HBP1	100	96.429	ENSSHAG00000010948	HBP1	98	90.329	Sarcophilus_harrisii
ENSG00000105856	HBP1	96	74.324	ENSSFOG00015011155	hbp1	100	67.767	Scleropages_formosus
ENSG00000105856	HBP1	97	61.589	ENSSMAG00000012631	-	94	53.308	Scophthalmus_maximus
ENSG00000105856	HBP1	97	71.141	ENSSMAG00000009892	hbp1	99	62.449	Scophthalmus_maximus
ENSG00000105856	HBP1	96	71.622	ENSSDUG00000022273	hbp1	99	62.986	Seriola_dumerili
ENSG00000105856	HBP1	97	64.474	ENSSDUG00000015387	-	96	53.484	Seriola_dumerili
ENSG00000105856	HBP1	94	64.583	ENSSLDG00000017324	-	99	55.894	Seriola_lalandi_dorsalis
ENSG00000105856	HBP1	96	71.622	ENSSLDG00000009669	hbp1	99	63.265	Seriola_lalandi_dorsalis
ENSG00000105856	HBP1	100	100.000	ENSSARG00000007731	HBP1	100	96.746	Sorex_araneus
ENSG00000105856	HBP1	100	89.286	ENSSPUG00000019157	HBP1	95	86.127	Sphenodon_punctatus
ENSG00000105856	HBP1	97	62.000	ENSSPAG00000009193	-	99	53.612	Stegastes_partitus
ENSG00000105856	HBP1	96	74.324	ENSSPAG00000004739	hbp1	99	62.781	Stegastes_partitus
ENSG00000105856	HBP1	100	97.143	ENSSSCG00000035673	HBP1	100	96.693	Sus_scrofa
ENSG00000105856	HBP1	100	92.857	ENSTGUG00000003100	HBP1	100	82.308	Taeniopygia_guttata
ENSG00000105856	HBP1	97	71.812	ENSTRUG00000016990	hbp1	99	62.012	Takifugu_rubripes
ENSG00000105856	HBP1	95	59.459	ENSTRUG00000011881	-	79	52.041	Takifugu_rubripes
ENSG00000105856	HBP1	96	71.622	ENSTNIG00000016027	hbp1	99	62.449	Tetraodon_nigroviridis
ENSG00000105856	HBP1	97	55.152	ENSTNIG00000002023	-	94	49.902	Tetraodon_nigroviridis
ENSG00000105856	HBP1	100	97.143	ENSTBEG00000007793	HBP1	100	84.630	Tupaia_belangeri
ENSG00000105856	HBP1	100	98.571	ENSTTRG00000006826	HBP1	100	95.525	Tursiops_truncatus
ENSG00000105856	HBP1	100	100.000	ENSUAMG00000005951	HBP1	98	96.693	Ursus_americanus
ENSG00000105856	HBP1	100	100.000	ENSUMAG00000018257	HBP1	98	96.498	Ursus_maritimus
ENSG00000105856	HBP1	90	87.664	ENSVPAG00000008629	HBP1	100	87.664	Vicugna_pacos
ENSG00000105856	HBP1	100	100.000	ENSVVUG00000022009	HBP1	98	96.498	Vulpes_vulpes
ENSG00000105856	HBP1	100	76.448	ENSXETG00000005922	hbp1	98	76.448	Xenopus_tropicalis
ENSG00000105856	HBP1	97	71.812	ENSXCOG00000020795	hbp1	91	62.268	Xiphophorus_couchianus
ENSG00000105856	HBP1	97	71.812	ENSXMAG00000016455	hbp1	99	62.577	Xiphophorus_maculatus
ENSG00000105856	HBP1	97	63.333	ENSXMAG00000007586	-	99	54.023	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	ISM	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	-	IEA	Function
GO:0005515	protein binding	23859194.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0007050	cell cycle arrest	9030690.	NAS	Process
GO:0016055	Wnt signaling pathway	-	IEA	Process
GO:0016607	nuclear speck	-	IDA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.