EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
18607064	Molecular detection of neuron-specific ELAV-like-positive cells in the peripheral blood of patients with small-cell lung cancer.	Cell Oncol	2008	D'Alessandro V	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr9	23693477	Frame_Shift_Ins	novel	*N241Kfs18**	0.38
ACC	chr9	23701606	Splice_Site	novel	X163_splice	0.42
ACC	chr9	23765008	Intron	novel		0.22
BLCA	chr9	23731073	Missense_Mutation	NA	E94D	0.21
BLCA	chr9	23731089	Missense_Mutation	novel	D89G	0.06
BLCA	chr9	23731041	Missense_Mutation	novel	L105R	0.43
BLCA	chr9	23701421	Missense_Mutation	NA	R224K	0.12
BLCA	chr9	23692863	Missense_Mutation	novel	D258E	0.07
BRCA	chr9	23692329	3'UTR	novel		0.3
BRCA	chr9	23690828	3'Flank	novel		0.19
BRCA	chr9	23691624	3'Flank	novel		0.13
BRCA	chr9	23762223	Frame_Shift_Ins	novel	*Q4Hfs22**	0.1	RRM_5
BRCA	chr9	23692711	Missense_Mutation	NA	R309H	0.04
CESC	chr9	23690806	3'Flank	novel		0.31
CESC	chr9	23690996	3'Flank	novel		0.26
CESC	chr9	23701538	Missense_Mutation	rs758305724	G185D	0.28
CESC	chr9	23691253	3'Flank	novel		0.18
CESC	chr9	23690169	3'Flank	novel		0.5
CESC	chr9	23704957	Missense_Mutation	rs568766646	R150C	0.34
CESC	chr9	23692079	3'UTR	rs571465628		0.55
CESC	chr9	23692326	3'UTR	novel		0.21
CESC	chr9	23762093	Nonsense_Mutation	NA	Q48*	0.11	RRM_5
CESC	chr9	23701543	Missense_Mutation	novel	I183M	0.6
CESC	chr9	23762106	Silent	rs141278970	V43V	0.48
CESC	chr9	23731046	Silent	novel	L103L	0.14
CHOL	chr9	23690363	3'Flank	novel		0.31
COAD	chr9	23704922	Silent	rs747705065	V161V	0.25
COAD	chr9	23701403	Missense_Mutation	novel	L230P	0.3
COAD	chr9	23704956	Missense_Mutation	novel	R150H	0.24
COAD	chr9	23762157	Silent	NA	S26S	0.4
COAD	chr9	23692545	3'UTR	novel		0.06
COAD	chr9	23731024	Missense_Mutation	novel	K111Q	0.7
COAD	chr9	23705041	Missense_Mutation	NA	I122V	0.21
COAD	chr9	23701566	Nonsense_Mutation	NA	R176*	0.31
COAD	chr9	23692726	Missense_Mutation	novel	N304S	0.07
COAD	chr9	23692805	Missense_Mutation	NA	I278L	0.25
COAD	chr9	23705024	Missense_Mutation	novel	L127F	0.16
COAD	chr9	23692263	3'UTR	novel		0.44
COAD	chr9	23701463	Frame_Shift_Ins	novel	*T210Nfs29**	0.11
COAD	chr9	23762185	Missense_Mutation	NA	G17A	0.37	RRM_5
COAD	chr9	23692321	3'UTR	novel		0.25
DLBC	chr9	23762081	Nonsense_Mutation	novel	Q52*	0.27	RRM_5
ESCA	chr9	23704943	Silent	novel	S154S	0.38
ESCA	chr9	23690152	3'Flank	novel		0.56
ESCA	chr9	23691516	3'Flank	novel		0.22
ESCA	chr9	23690997	3'Flank	novel		0.42
ESCA	chr9	23690408	3'Flank	novel		0.28
ESCA	chr9	23691152	3'Flank	novel		0.08
ESCA	chr9	23692819	Missense_Mutation	NA	G273E	0.4
ESCA	chr9	23690234	3'Flank	novel		0.76
ESCA	chr9	23690731	3'Flank	novel		0.34
ESCA	chr9	23691516	3'Flank	novel		0.42
ESCA	chr9	23692569	Silent	rs372576559	T356T	0.33
ESCA	chr9	23692297	3'UTR	novel		0.4
ESCA	chr9	23704935	Missense_Mutation	novel	L157R	0.41
ESCA	chr9	23691892	3'UTR	novel		0.47
GBM	chr9	23701593	Missense_Mutation	rs748871054	G167C	0.45
GBM	chr9	23762067	Missense_Mutation	novel	K56N	0.2	RRM_5
GBM	chr9	23765011	Intron	rs777529292		0.25
HNSC	chr9	23765015	Intron	novel		0.1
HNSC	chr9	23762149	Missense_Mutation	novel	V29A	0.11	RRM_5
HNSC	chr9	23704956	Missense_Mutation	novel	R150P	0.07
HNSC	chr9	23692609	Missense_Mutation	novel	G343E	0.41
HNSC	chr9	23731117	Missense_Mutation	novel	L80M	0.31
HNSC	chr9	23762232	Translation_Start_Site	novel	M1?	0.28	RRM_5
HNSC	chr9	23704930	Missense_Mutation	novel	D159H	0.15
HNSC	chr9	23701498	Silent	novel	I198I	0.23
KIRC	chr9	23705051	Silent	NA	S118S	0.29
KIRC	chr9	23704957	Missense_Mutation	rs568766646	R150C	0.06
KIRP	chr9	23762207	Missense_Mutation	NA	T10A	0.19	RRM_5
LGG	chr9	23701566	Nonsense_Mutation	NA	R176*	0.07
LIHC	chr9	23705040	Missense_Mutation	novel	I122T	0.07
LIHC	chr9	23762195	Missense_Mutation	novel	T14A	0.32	RRM_5
LIHC	chr9	23692403	3'UTR	novel		0.4
LUAD	chr9	23692778	Missense_Mutation	novel	A287S	0.35
LUAD	chr9	23692664	Missense_Mutation	NA	T325S	0.26
LUAD	chr9	23705018	Silent	rs372563684	V129V	0.09
LUAD	chr9	23701547	Missense_Mutation	novel	A182V	0.38
LUAD	chr9	23692848	Missense_Mutation	NA	L263F	0.26
LUAD	chr9	23693458	Missense_Mutation	NA	G248R	0.12
LUAD	chr9	23701586	Missense_Mutation	novel	G169V	0.13
LUAD	chr9	23692772	Missense_Mutation	NA	E289Q	0.18
LUAD	chr9	23704927	Nonsense_Mutation	novel	Q160*	0.39
LUAD	chr9	23701587	Missense_Mutation	NA	G169W	0.43
LUAD	chr9	23762205	Silent	novel	T10T	0.19
LUAD	chr9	23762139	Silent	novel	G32G	0.33
LUAD	chr9	23701603	Splice_Region	rs773876308	G163G	0.2
LUAD	chr9	23762247	Splice_Site	NA		0.35
LUAD	chr9	23701400	Missense_Mutation	NA	A231D	0.2
LUSC	chr9	23701423	Silent	rs767990129	N223N	0.41
LUSC	chr9	23701400	Missense_Mutation	novel	A231V	0.21
LUSC	chr9	23692678	Missense_Mutation	rs780367763	G320V	0.27
LUSC	chr9	23701386	Missense_Mutation	NA	R236G	0.14
LUSC	chr9	23762158	Nonsense_Mutation	novel	S26*	0.21	RRM_5
LUSC	chr9	23692829	Missense_Mutation	novel	G270R	0.23
LUSC	chr9	23762133	Silent	NA	T34T	0.6
LUSC	chr9	23762134	Missense_Mutation	NA	T34K	0.61	RRM_5
LUSC	chr9	23701404	Silent	novel	L230L	0.57
LUSC	chr9	23692787	Missense_Mutation	novel	A284S	0.2
LUSC	chr9	23692788	Silent	novel	L283L	0.21
LUSC	chr9	23692770	Missense_Mutation	novel	E289D	0.73
LUSC	chr9	23701596	Missense_Mutation	NA	R166W	0.42
LUSC	chr9	23692779	Missense_Mutation	novel	D286E	0.4
LUSC	chr9	23692820	Missense_Mutation	NA	G273R	0.46
LUSC	chr9	23701559	Missense_Mutation	novel	E178G	0.05
MESO	chr9	23705061	Missense_Mutation	novel	A115D	0.17
OV	chr9	23692600	Missense_Mutation	NA	V346E	0.43
OV	chr9	23692737	Silent	NA	G300G	0.57
OV	chr9	23762250	Splice_Region	novel		0.05
OV	chr9	23765070	Intron	novel		0.36
OV	chr9	23692359	3'UTR	novel		0.35
OV	chr9	23762156	Missense_Mutation	novel	S27T	0.1	RRM_5
PAAD	chr9	23692690	Missense_Mutation	rs769220559	C316Y	0.16
PAAD	chr9	23701386	Missense_Mutation	rs772784712	R236C	0.04
PAAD	chr9	23705057	Silent	novel	R116R	0.2
PAAD	chr9	23765068	Intron	novel		0.21
PAAD	chr9	23692695	Missense_Mutation	novel	N314K	0.04
PRAD	chr9	23731125	Missense_Mutation	NA	G77A	0.38
PRAD	chr9	23692532	3'UTR	novel		0.2
PRAD	chr9	23701425	Missense_Mutation	NA	N223D	0.12
READ	chr9	23762158	Missense_Mutation	rs146832864	S26L	0.39	RRM_5
READ	chr9	23701473	Missense_Mutation	NA	S207R	0.18
SARC	chr9	23691893	3'UTR	novel		0.11
SARC	chr9	23765030	Intron	novel		0.23
SKCM	chr9	23692544	3'UTR	novel		0.22
SKCM	chr9	23762096	Missense_Mutation	novel	P47S	0.9	RRM_5
SKCM	chr9	23701507	Silent	rs768188398	T195T	0.18
SKCM	chr9	23704942	Missense_Mutation	NA	R155C	0.57
SKCM	chr9	23765043	Intron	novel		0.83
SKCM	chr9	23701463	Missense_Mutation	NA	T210I	0.08
SKCM	chr9	23701578	Nonsense_Mutation	NA	R172*	0.86
SKCM	chr9	23705043	Missense_Mutation	NA	S121C	0.91
SKCM	chr9	23762231	Missense_Mutation	NA	E2K	0.29	RRM_5
SKCM	chr9	23692819	Missense_Mutation	NA	G273E	0.08
SKCM	chr9	23762158	Missense_Mutation	rs146832864	S26L	0.26	RRM_5
SKCM	chr9	23692810	Nonsense_Mutation	NA	W276*	0.25
SKCM	chr9	23692790	Silent	novel	L283L	0.65
SKCM	chr9	23765036	Intron	rs780922027		0.28
SKCM	chr9	23762045	Missense_Mutation	NA	E64K	0.2
SKCM	chr9	23704988	Silent	NA	K139K	0.35
SKCM	chr9	23765008	Intron	novel		0.32
SKCM	chr9	23705066	Silent	NA	S113S	0.64
SKCM	chr9	23705067	Missense_Mutation	NA	S113F	0.69
SKCM	chr9	23762055	Silent	novel	G60G	0.12
SKCM	chr9	23692799	Missense_Mutation	NA	V280L	0.43
SKCM	chr9	23731086	Missense_Mutation	NA	P90L	0.38
SKCM	chr9	23692764	Silent	NA	I291I	0.77
SKCM	chr9	23762158	Missense_Mutation	rs146832864	S26L	0.54	RRM_5
SKCM	chr9	23704931	Silent	NA	V158V	0.11
SKCM	chr9	23704968	Missense_Mutation	NA	S146L	0.15
SKCM	chr9	23701408	Silent	NA	G228G	0.64
SKCM	chr9	23731050	Missense_Mutation	NA	G102E	0.61
SKCM	chr9	23705035	Missense_Mutation	novel	D124N	0.19
SKCM	chr9	23762247	Splice_Site	NA		0.56
SKCM	chr9	23704942	Missense_Mutation	NA	R155C	0.78
SKCM	chr9	23762231	Missense_Mutation	NA	E2K	0.68	RRM_5
SKCM	chr9	23692857	Missense_Mutation	NA	M260I	0.22
SKCM	chr9	23701577	Missense_Mutation	NA	R172Q	0.92
SKCM	chr9	23692764	Silent	NA	I291I	0.7
SKCM	chr9	23704976	Silent	rs767310033	Q143Q	0.51
SKCM	chr9	23701492	Silent	novel	V200V	0.43
SKCM	chr9	23701591	Silent	NA	G167G	0.04
SKCM	chr9	23692588	Missense_Mutation	NA	S350F	1
SKCM	chr9	23731113	Missense_Mutation	NA	G81E	0.35
SKCM	chr9	23701598	Missense_Mutation	NA	S165L	0.74
SKCM	chr9	23704988	Missense_Mutation	NA	K139N	0.39
STAD	chr9	23692863	Silent	rs138657080	D258D	0.33
STAD	chr9	23762087	Missense_Mutation	rs753157617	M50V	0.05	RRM_5
STAD	chr9	23762154	Silent	NA	S27S	0.33
STAD	chr9	23762122	Missense_Mutation	NA	K38R	0.17	RRM_5
STAD	chr9	23731064	Missense_Mutation	NA	I97M	0.06
STAD	chr9	23692747	Missense_Mutation	novel	G297E	0.09
STAD	chr9	23701595	Missense_Mutation	NA	R166M	0.31
STAD	chr9	23731062	Missense_Mutation	novel	N98I	0.12
STAD	chr9	23701498	Missense_Mutation	NA	I198M	0.59
STAD	chr9	23705058	Missense_Mutation	NA	R116H	0.41
STAD	chr9	23704957	Missense_Mutation	rs568766646	R150C	0.06
STAD	chr9	23762098	Missense_Mutation	NA	L46P	0.14	RRM_5
STAD	chr9	23762206	Missense_Mutation	novel	T10I	0.22	RRM_5
STAD	chr9	23692862	Missense_Mutation	NA	G259R	0.42
STAD	chr9	23692712	Missense_Mutation	novel	R309C	0.21
STAD	chr9	23705058	Missense_Mutation	NA	R116H	0.34
THYM	chr9	23690649	3'Flank	novel		0.09
UCEC	chr9	23701378	Splice_Site	novel	X238_splice	0.04
UCEC	chr9	23762101	Missense_Mutation	NA	Y45C	0.29	RRM_5
UCEC	chr9	23691719	3'Flank	novel		0.33
UCEC	chr9	23690408	3'Flank	novel		0.23
UCEC	chr9	23692772	Nonsense_Mutation	novel	E289*	0.07
UCEC	chr9	23690292	3'Flank	novel		0.29
UCEC	chr9	23692109	3'UTR	novel		0.26
UCEC	chr9	23762198	Missense_Mutation	novel	N13H	0.36	RRM_5
UCEC	chr9	23691166	3'Flank	novel		0.19
UCEC	chr9	23691762	3'Flank	novel		0.36
UCEC	chr9	23690953	3'Flank	novel		0.31
UCEC	chr9	23690274	3'Flank	novel		0.53
UCEC	chr9	23731047	Missense_Mutation	novel	L103S	0.36
UCEC	chr9	23691023	3'Flank	novel		0.36
UCEC	chr9	23691576	3'Flank	novel		0.29
UCEC	chr9	23690311	3'Flank	novel		0.41
UCEC	chr9	23691637	3'Flank	novel		0.57
UCEC	chr9	23691930	3'UTR	novel		0.42
UCEC	chr9	23692206	3'UTR	novel		0.5
UCEC	chr9	23701545	Missense_Mutation	novel	I183V	0.34
UCEC	chr9	23690369	3'Flank	novel		0.21
UCEC	chr9	23704931	Silent	NA	V158V	0.16
UCEC	chr9	23692735	Missense_Mutation	NA	A301D	0.18
UCEC	chr9	23705001	Missense_Mutation	novel	T135I	0.14
UCEC	chr9	23691763	3'Flank	novel		0.34
UCEC	chr9	23691442	3'Flank	novel		0.36
UCEC	chr9	23691701	3'Flank	novel		0.22
UCEC	chr9	23692742	Missense_Mutation	novel	F299V	0.47
UCEC	chr9	23691093	3'Flank	novel		0.44
UCEC	chr9	23691457	3'Flank	novel		0.36
UCEC	chr9	23691649	3'Flank	rs547077075		0.43
UCEC	chr9	23692380	3'UTR	novel		0.58
UCEC	chr9	23704959	Missense_Mutation	NA	G149E	0.32
UCEC	chr9	23690667	3'Flank	novel		0.56
UCEC	chr9	23691452	3'Flank	novel		0.4
UCEC	chr9	23691264	3'Flank	novel		0.3
UCEC	chr9	23690584	3'Flank	novel		0.36
UCEC	chr9	23691023	3'Flank	novel		0.42
UCEC	chr9	23691736	3'Flank	novel		0.36
UCEC	chr9	23690746	3'Flank	novel		0.41
UCEC	chr9	23690408	3'Flank	novel		0.35
UCEC	chr9	23690668	3'Flank	rs765970343		0.72
UCEC	chr9	23691100	3'Flank	novel		0.18
UCEC	chr9	23691884	3'UTR	novel		0.15
UCEC	chr9	23692843	Missense_Mutation	novel	G265V	0.19
UCEC	chr9	23705003	Missense_Mutation	novel	K134N	0.64
UCEC	chr9	23690244	3'Flank	novel		0.33
UCEC	chr9	23690668	3'Flank	rs765970343		0.27
UCEC	chr9	23691245	3'Flank	novel		0.35
UCEC	chr9	23691514	3'Flank	novel		0.26
UCEC	chr9	23692004	3'UTR	novel		0.28
UCEC	chr9	23692160	3'UTR	novel		0.4
UCEC	chr9	23690994	3'Flank	novel		0.21
UCEC	chr9	23691475	3'Flank	novel		0.2
UCEC	chr9	23692422	3'UTR	novel		0.14
UCEC	chr9	23690408	3'Flank	novel		0.5
UCEC	chr9	23690666	3'Flank	novel		0.2
UCEC	chr9	23690766	3'Flank	novel		0.38
UCEC	chr9	23691517	3'Flank	novel		0.5
UCEC	chr9	23691256	3'Flank	novel		0.39
UCEC	chr9	23690632	3'Flank	novel		0.38
UCEC	chr9	23692313	3'UTR	novel		0.52
UCEC	chr9	23705054	Silent	novel	P117P	0.24
UCEC	chr9	23691516	3'Flank	novel		0.24
UCEC	chr9	23690662	3'Flank	novel		0.44
UCEC	chr9	23692533	3'UTR	novel		0.55
UCEC	chr9	23692839	Silent	novel	I266I	0.43
UCEC	chr9	23690822	3'Flank	novel		0.2
UCEC	chr9	23704941	Missense_Mutation	novel	R155H	0.38
UCEC	chr9	23691578	3'Flank	novel		0.33
UCEC	chr9	23692167	3'UTR	rs202039694		0.49
UCEC	chr9	23690432	3'Flank	novel		0.14
UCEC	chr9	23692004	3'UTR	novel		0.38
UCEC	chr9	23691516	3'Flank	novel		0.26
UCEC	chr9	23731073	Silent	rs201108944	E94E	0.39
UCEC	chr9	23691432	3'Flank	novel		0.28
UCEC	chr9	23731106	Silent	novel	G83G	0.5
UCEC	chr9	23701575	Missense_Mutation	novel	F173L	0.23
UCEC	chr9	23691905	3'UTR	novel		0.29
UCEC	chr9	23690408	3'Flank	novel		0.39
UCEC	chr9	23701520	In_Frame_Ins	novel	P191delinsQVDS	0.03
UCEC	chr9	23690996	3'Flank	novel		0.05
UCEC	chr9	23701516	Silent	rs542871954	P192P	0.23
UCEC	chr9	23701463	Missense_Mutation	novel	T210N	0.3
UCEC	chr9	23731021	Splice_Site	novel	X111_splice	0.26
UCEC	chr9	23762082	Silent	NA	T51T	0.22
UCEC	chr9	23691822	3'UTR	novel		0.36
UCEC	chr9	23692313	3'UTR	novel		0.54
UCEC	chr9	23692405	3'UTR	novel		0.52
UCEC	chr9	23692853	Missense_Mutation	novel	S262C	0.2
UCEC	chr9	23690625	3'Flank	novel		0.5
UCEC	chr9	23690244	3'Flank	novel		0.42
UCEC	chr9	23691514	3'Flank	novel		0.34
UCEC	chr9	23691719	3'Flank	novel		0.24
UCEC	chr9	23691900	3'UTR	novel		0.26
UCEC	chr9	23692249	3'UTR	novel		0.52
UCEC	chr9	23690339	3'Flank	novel		0.36
UCEC	chr9	23765026	Intron	novel		0.44
UCS	chr9	23692554	3'UTR	novel		0.37
UCS	chr9	23762160	Missense_Mutation	novel	C25W	0.05	RRM_5
UCS	chr9	23692639	Missense_Mutation	NA	A333V	0.29

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LAML	DEL	0.0052	0.24147
TGCT	DEL	0.34	7.3329e-05
THCA	DEL	0.0301	0.24038
THYM	DEL	0.0325	0.022012

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00038	Kaplan-Meier Survival Analysis
SARC	0.013	Kaplan-Meier Survival Analysis
MESO	0.0014	Kaplan-Meier Survival Analysis
KIRP	0.025	Kaplan-Meier Survival Analysis
PAAD	0.002	Kaplan-Meier Survival Analysis
READ	0.041	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.048	Kaplan-Meier Survival Analysis
UVM	0.01	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000107105 (Gene tree)
Gene ID: 1993
Gene Symbol: ELAVL2
Alias: HuB|HEL-N1
Full Name: ELAV like RNA binding protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 160,603 bases
Position: chr9:23,690,104-23,850,706
Accession: 3313
RBP type: canonical RBP
Summary: The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000223951	RRM_5	PF13893.6	3.2e-12	1	2
ENSP00000223951	RRM_5	PF13893.6	3.2e-12	2	2
ENSP00000369460	RRM_5	PF13893.6	3.8e-12	1	2
ENSP00000369460	RRM_5	PF13893.6	3.8e-12	2	2
ENSP00000380479	RRM_5	PF13893.6	3.8e-12	1	2
ENSP00000380479	RRM_5	PF13893.6	3.8e-12	2	2
ENSP00000440998	RRM_5	PF13893.6	3.8e-12	1	2
ENSP00000440998	RRM_5	PF13893.6	3.8e-12	2	2
ENSP00000369453	RRM_5	PF13893.6	5.5e-12	1	2
ENSP00000369453	RRM_5	PF13893.6	5.5e-12	2	2
ENSP00000412602	RRM_5	PF13893.6	1.5e-05	1	1
ENSP00000223951	RRM_1	PF00076.22	2.4e-66	1	3
ENSP00000223951	RRM_1	PF00076.22	2.4e-66	2	3
ENSP00000223951	RRM_1	PF00076.22	2.4e-66	3	3
ENSP00000369460	RRM_1	PF00076.22	2.9e-66	1	3
ENSP00000369460	RRM_1	PF00076.22	2.9e-66	2	3
ENSP00000369460	RRM_1	PF00076.22	2.9e-66	3	3
ENSP00000380479	RRM_1	PF00076.22	2.9e-66	1	3
ENSP00000380479	RRM_1	PF00076.22	2.9e-66	2	3
ENSP00000380479	RRM_1	PF00076.22	2.9e-66	3	3
ENSP00000440998	RRM_1	PF00076.22	2.9e-66	1	3
ENSP00000440998	RRM_1	PF00076.22	2.9e-66	2	3
ENSP00000440998	RRM_1	PF00076.22	2.9e-66	3	3
ENSP00000369453	RRM_1	PF00076.22	4.2e-66	1	3
ENSP00000369453	RRM_1	PF00076.22	4.2e-66	2	3
ENSP00000369453	RRM_1	PF00076.22	4.2e-66	3	3
ENSP00000412602	RRM_1	PF00076.22	2.3e-42	1	2
ENSP00000412602	RRM_1	PF00076.22	2.3e-42	2	2
ENSP00000391757	RRM_1	PF00076.22	3.7e-15	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
8497264	Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.	Mol Cell Biol	1993 Jun	Levine TD	-
8158249	Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor.	J Neurosci	1994 Apr	King PH	-
21337467	Regulation of hub mRNA stability and translation by miR430 and the dead end protein promotes preferential expression in zebrafish primordial germ cells.	Dev Dyn	2011 Mar	Mickoleit M	doi: 10.1002/dvdy.22571.
8643372	Hel-N1, an RNA-binding protein, is a ligand for an A + U rich region of the GLUT1 3' UTR.	Nucleic Acids Symp Ser	1995	Jain RG	-
11573004	Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins.	Proc Natl Acad Sci U S A	2001 Sep 25	Quattrone A	-
7541976	Hu antigens: reactivity with Hu antibodies, tumor expression, and major immunogenic sites.	Ann Neurol	1995 Jul	Manley GT	-
10079173	Analysis of the RNA recognition motifs of human neuronal ELAV-like proteins in binding to a cytokine mRNA.	Biochem Biophys Res Commun	1999 Mar 16	Sakai K	-
9815574	Neuron-specific hel-N1 and HuD as novel molecular markers of neuroblastoma: a correlation of HuD messenger RNA levels with favorable prognostic features.	Clin Cancer Res	1997 Oct	Ball NS	-
9393760	Genomic organization and mutation analysis of Hel-N1 in lung cancers with chromosome 9p21 deletions.	Cancer Res	1997 Dec 1	Cairns P	-
10449789	Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems.	Proc Natl Acad Sci U S A	1999 Aug 17	Akamatsu W	-
9045688	The Elav-like proteins bind to a conserved regulatory element in the 3'-untranslated region of GAP-43 mRNA.	J Biol Chem	1997 Mar 7	Chung S	-
9001249	Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes.	Mol Cell Biol	1997 Feb	Jain RG	-
8619556	Expression of Hel-N1 and Hel-N2 in small-cell lung carcinoma.	Ann Neurol	1996 May	King PH	-
8053656	Autoantibodies against the Hel-N1 RNA-binding protein among patients with lung carcinoma: an association with type I anti-neuronal nuclear antibodies.	Ann Neurol	1994 Aug	Dropcho EJ	-
8036161	GRSF-1: a poly(A)+ mRNA binding protein which interacts with a conserved G-rich element.	Nucleic Acids Res	1994 Jun 25	Qian Z	-
7972035	Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.	Proc Natl Acad Sci U S A	1994 Nov 8	Gao FB	-
7828887	Hel-N2: a novel isoform of Hel-N1 which is conserved in rat neural tissue and produced in early embryogenesis.	Gene	1994 Dec 30	King PH	-
12900401	Characterization of the interaction between neuronal RNA-binding protein HuD and AU-rich RNA.	J Biol Chem	2003 Oct 10	Park-Lee S	-
15764704	The RNA-binding protein HuD regulates neuronal cell identity and maturation.	Proc Natl Acad Sci U S A	2005 Mar 22	Akamatsu W	-
14745023	Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory.	Proc Natl Acad Sci U S A	2004 Feb 3	Pascale A	-
20159993	Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members.	Nucleic Acids Res	2010 Jun	Wang H	doi: 10.1093/nar/gkq028
20047656	A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins.	BMC Bioinformatics	2010 Jan 4	Enstero M	doi: 10.1186/1471-2105-11-6.
18405437	Bovine oocytes and early embryos express Staufen and ELAVL RNA-binding proteins.	Zygote	2008 May	Calder MD	doi: 10.1017/S096719940700456X.
17035636	A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators.	Mol Biol Cell	2006 Dec	Zhu H	-
21695151	HuB (elavl2) mRNA is restricted to the germ cells by post-transcriptional mechanisms including stabilisation of the message by DAZL.	PLoS One	2011	Wiszniak SE	doi: 10.1371/journal.pone.0020773
21368052	MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors.	J Neurosci	2011 Mar 2	Shibata M	doi: 10.1523/JNEUROSCI.5085-10.2011.
27071691	The exon junction complex in neural development and neurodevelopmental disease.	Int J Dev Neurosci	2016 Dec	McMahon JJ	doi: 10.1016/j.ijdevneu.2016.03.006
26325429	Acute reduction of neuronal RNA binding Elavl2 protein and Gap43 mRNA in mouse hippocampus after kainic acid treatment.	Biochem Biophys Res Commun	2015 Oct 9	Ohtsuka T	doi: 10.1016/j.bbrc.2015.08.103
29614249	Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.	Neurosci Res	2018 Oct	Ogawa Y	doi: 10.1016/j.neures.2018.03.008
29626565	Antidepressant-like actions by silencing of neuronal ELAV-like RNA-binding proteins HuB and HuC in a model of depression in male mice.	Neuropharmacology	2018 Jun	Sanna MD	doi: 10.1016/j.neuropharm.2018.04.001
30696738	Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1.	MBio	2019 Jan 29	Xu J	doi: 10.1128/mBio.02687-18.
31013625	RNA-Binding Proteins HuB, HuC, and HuD are Distinctly Regulated in Dorsal Root Ganglia Neurons from STZ-Sensitive Compared to STZ-Resistant Diabetic Mice.	Int J Mol Sci	2019 Apr 22	Mustaciosu CC	doi: 10.3390/ijms20081965.
31037778	Integrative analyses of key genes and regulatory elements in fluoride-affected osteosarcoma.	J Cell Biochem	2019 Sep	Li M	doi: 10.1002/jcb.28807

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000223951	ELAVL2-201	3763	-	ENSP00000223951	346 (aa)	-	Q12926
ENST00000462649	ELAVL2-207	424	-	-	- (aa)	-	-
ENST00000440102	ELAVL2-206	723	-	ENSP00000412602	189 (aa)	-	B1AM48
ENST00000397312	ELAVL2-204	3805	-	ENSP00000380479	359 (aa)	-	Q12926
ENST00000423281	ELAVL2-205	777	XM_024447438	ENSP00000391757	90 (aa)	XP_024303206	C9JB16
ENST00000544538	ELAVL2-208	3789	XM_005251393	ENSP00000440998	359 (aa)	XP_005251450	Q12926
ENST00000380110	ELAVL2-202	3691	XM_006716735	ENSP00000369453	389 (aa)	XP_006716798	A0A0A0MRX1
ENST00000380117	ELAVL2-203	2370	-	ENSP00000369460	359 (aa)	-	Q12926

Gene Model

Click here to download ENSG00000107105's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000107105	Prostatic Neoplasms	5.1290000E-005	21372204
ENSG00000107105	Prostatic Neoplasms	8.9460000E-005	18264096
ENSG00000107105	Heart Failure	6.7967817E-004	-
ENSG00000107105	Anthropometry	9.2820000E-005	-
ENSG00000107105	Coronary Artery Disease	8.3860000E-005	-
ENSG00000107105	Cardiovascular System	3.9620000E-005	-
ENSG00000107105	Cardiovascular System	5.0150000E-005	-
ENSG00000107105	Cardiovascular Physiological Phenomena	2.0450000E-005	-
ENSG00000107105	Platelet Function Tests	3.5100000E-006	-
ENSG00000107105	Platelet Function Tests	1.6125500E-005	-
ENSG00000107105	Platelet Function Tests	2.0499800E-005	-
ENSG00000107105	Platelet Function Tests	8.0477812E-006	-
ENSG00000107105	Platelet Function Tests	1.1963553E-006	-
ENSG00000107105	Platelet Function Tests	3.4194549E-007	-
ENSG00000107105	Platelet Function Tests	1.8164455E-007	-
ENSG00000107105	Platelet Function Tests	5.1248542E-006	-
ENSG00000107105	Platelet Function Tests	2.8057700E-005	-
ENSG00000107105	Child Development Disorders, Pervasive	1.3861000E-005	-
ENSG00000107105	Child Development Disorders, Pervasive	1.7001000E-006	-
ENSG00000107105	Child Development Disorders, Pervasive	1.4349000E-005	-
ENSG00000107105	Body Weight	3E-6	19197348
ENSG00000107105	S-(3-hydroxypropyl)cysteine N-acetate	5E-8	26053186
ENSG00000107105	Smoking Cessation	5E-8	26053186
ENSG00000107105	fibrinogen D fragment	6E-6	21502573

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000107105	rs3793577	9	23737629	A	Neuroticism	29255261	z score decrease	5.066	EFO_0007660
ENSG00000107105	rs2026037	9	23762531	T	Intelligence (MTAG)	29326435	[0.015-0.031] unit increase	0.023047743	EFO_0004337
ENSG00000107105	rs702222	9	23805571	T	Cognitive performance	30038396	[0.014-0.026] unit decrease	0.02	EFO_0008354
ENSG00000107105	rs1329044	9	23747793	T	Educational attainment (MTAG)	30038396	[0.012-0.018] unit increase	0.015	EFO_0004784
ENSG00000107105	rs1329044	9	23747793	T	Self-reported math ability	30038396	[0.016-0.026] unit increase	0.0213	EFO_0004875
ENSG00000107105	rs7038525	9	23772279	C	Highest math class taken	30038396	[0.015-0.027] unit increase	0.0208	EFO_0004875
ENSG00000107105	rs1329044	9	23747793	T	Self-reported math ability (MTAG)	30038396	[0.018-0.027] unit increase	0.0227	EFO_0004875
ENSG00000107105	rs1329044	9	23747793	T	Highest math class taken (MTAG)	30038396	[0.018-0.027] unit increase	0.0223	EFO_0004875
ENSG00000107105	rs7038525	9	23772279	T	Cognitive performance (MTAG)	30038396	[0.018-0.03] unit decrease	0.0241	EFO_0008354
ENSG00000107105	rs702223	9	23813842	A	General cognitive ability	29844566	z-score decrease	6.409	EFO_0004337
ENSG00000107105	rs7038525	9	23772279	T	General cognitive ability	29844566	z-score decrease	5.929	EFO_0004337
ENSG00000107105	rs810681	9	23799241	A	General cognitive ability	29844566	z-score decrease	5.632	EFO_0004337
ENSG00000107105	rs702222	9	23805571	T	Intelligence	29942086	z-score decrease	6.905	EFO_0004337
ENSG00000107105	rs7038525	9	23772279	T	Intelligence	29942086	z-score decrease	5.957	EFO_0004337
ENSG00000107105	rs810681	9	23799241	A	Intelligence	29942086	z-score decrease	5.77	EFO_0004337
ENSG00000107105	rs10811965	9	23741280	T	Depression	29942085	z score decrease	5.629	EFO_0003761
ENSG00000107105	rs3793577	9	23737629	A	Depression	29942085	z score decrease	6.992	EFO_0003761
ENSG00000107105	rs10119773	9	23736402	A	Feeling guilty	29500382	z score decrease	6.62	EFO_0009595
ENSG00000107105	rs10119773	9	23736402	A	Neurociticism	29500382	z score decrease	6.83	EFO_0007660
ENSG00000107105	rs12057071	9	23759370	C	Glomerular filtration rate change in heart transplantation	30160337	[7.89-18.39] unit increase	13.14	EFO_0007043\|EFO_0006829
ENSG00000107105	rs10119773	9	23736402	A	Neuroticism	29942085	z score decrease	5.997	EFO_0007660
ENSG00000107105	rs1329044	9	23747793	T	Educational attainment (years of education)	30038396	[0.0097-0.0171] unit increase	0.0134	EFO_0004784
ENSG00000107105	rs11793074	9	23820072	A	Insomnia symptoms (never/rarely vs. usually)	30804566	[1.02-1.05]	1.03	EFO_0007876
ENSG00000107105	rs11793074	9	23820072	A	Insomnia symptoms (never/rarely vs. sometimes/usually)	30804566	[1.02-1.05]	1.03	EFO_0007876
ENSG00000107105	rs2771046	9	23810890	A	Alcohol consumption (drinks per week) (MTAG)	30643251	[0.0062-0.0128] unit increase	0.00946371	EFO_0007878
ENSG00000107105	rs3793577	9	23737629	G	Depression	30718901	[1.02-1.03]	1.0214505	EFO_0003761
ENSG00000107105	rs3793577	9	23737629	G	Positive affect	30643256	[0.0059-0.0103] unit increase	0.00809184	EFO_0007869
ENSG00000107105	rs12236195	9	23751702	T	Positive affect	30643256	[0.0054-0.011] unit increase	0.008193224	EFO_0007869
ENSG00000107105	rs3793577	9	23737629	G	Neuroticism	30643256	[0.0077-0.0134] unit increase	0.010534243	EFO_0007660
ENSG00000107105	rs12236195	9	23751702	T	Neuroticism	30643256	[0.0071-0.0144] unit increase	0.010758697	EFO_0007660
ENSG00000107105	rs3793577	9	23737629	G	Depressive symptoms	30643256	[0.0049-0.0086] unit increase	0.006741048	EFO_0007006
ENSG00000107105	rs12236195	9	23751702	T	Depressive symptoms	30643256	[0.0045-0.0091] unit increase	0.006799609	EFO_0007006
ENSG00000107105	rs10119773	9	23736402	?	Neuroticism	30595370			EFO_0007660
ENSG00000107105	rs3793577	9	23737629	G	Well-being spectrum (multivariate analysis)	30643256	[0.0048-0.0084] unit increase	0.006601051	EFO_0007869
ENSG00000107105	rs3793577	9	23737629	G	Life satisfaction	30643256	[0.0062-0.011] unit increase	0.008610851	EFO_0007869

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000107105's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000107105	ELAVL2	88	34.783	ENSG00000155636	RBM45	61	34.783
ENSG00000107105	ELAVL2	93	30.939	ENSG00000143368	SF3B4	74	35.294
ENSG00000107105	ELAVL2	91	37.079	ENSG00000076067	RBMS2	56	36.181
ENSG00000107105	ELAVL2	84	37.342	ENSG00000153250	RBMS1	94	38.095
ENSG00000107105	ELAVL2	89	37.349	ENSG00000070756	PABPC1	95	41.935
ENSG00000107105	ELAVL2	89	32.450	ENSG00000151846	PABPC3	61	32.450
ENSG00000107105	ELAVL2	79	32.468	ENSG00000161547	SRSF2	70	32.468
ENSG00000107105	ELAVL2	79	34.211	ENSG00000184388	PABPC1L2B	80	34.211
ENSG00000107105	ELAVL2	89	35.802	ENSG00000174740	PABPC5	97	35.802
ENSG00000107105	ELAVL2	96	34.615	ENSG00000116001	TIA1	84	34.615
ENSG00000107105	ELAVL2	99	30.337	ENSG00000254535	PABPC4L	94	30.178
ENSG00000107105	ELAVL2	71	37.097	ENSG00000132819	RBM38	59	37.097
ENSG00000107105	ELAVL2	78	30.201	ENSG00000099783	HNRNPM	52	30.201
ENSG00000107105	ELAVL2	90	32.692	ENSG00000149187	CELF1	93	32.955
ENSG00000107105	ELAVL2	89	30.000	ENSG00000138668	HNRNPD	99	36.170
ENSG00000107105	ELAVL2	100	31.522	ENSG00000140488	CELF6	90	37.037
ENSG00000107105	ELAVL2	91	38.202	ENSG00000144642	RBMS3	82	36.667
ENSG00000107105	ELAVL2	79	34.211	ENSG00000186288	PABPC1L2A	80	34.211
ENSG00000107105	ELAVL2	75	35.714	ENSG00000179950	PUF60	62	35.714
ENSG00000107105	ELAVL2	89	34.940	ENSG00000090621	PABPC4	97	35.294
ENSG00000107105	ELAVL2	83	40.816	ENSG00000161082	CELF5	89	30.857
ENSG00000107105	ELAVL2	93	34.615	ENSG00000151923	TIAL1	91	35.211
ENSG00000107105	ELAVL2	91	35.135	ENSG00000100461	RBM23	63	35.135
ENSG00000107105	ELAVL2	78	35.714	ENSG00000213516	RBMXL1	53	34.118
ENSG00000107105	ELAVL2	93	40.000	ENSG00000101104	PABPC1L	96	40.000
ENSG00000107105	ELAVL2	100	34.066	ENSG00000101489	CELF4	62	36.000
ENSG00000107105	ELAVL2	100	94.444	ENSG00000162374	ELAVL4	99	89.071
ENSG00000107105	ELAVL2	90	34.615	ENSG00000048740	CELF2	60	39.506
ENSG00000107105	ELAVL2	77	36.364	ENSG00000099622	CIRBP	94	37.500
ENSG00000107105	ELAVL2	78	35.714	ENSG00000147274	RBMX	87	34.328
ENSG00000107105	ELAVL2	81	31.507	ENSG00000130811	EIF3G	64	31.944
ENSG00000107105	ELAVL2	74	31.343	ENSG00000265241	RBM8A	70	33.784
ENSG00000107105	ELAVL2	100	87.778	ENSG00000196361	ELAVL3	99	80.874
ENSG00000107105	ELAVL2	89	41.975	ENSG00000159409	CELF3	63	41.975
ENSG00000107105	ELAVL2	92	40.541	ENSG00000131051	RBM39	93	40.000
ENSG00000107105	ELAVL2	88	31.579	ENSG00000120948	TARDBP	53	31.579
ENSG00000107105	ELAVL2	100	71.111	ENSG00000066044	ELAVL1	97	76.948

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000107105	ELAVL2	100	94.180	ENSAPOG00000022121	ELAVL2	100	92.031	Acanthochromis_polyacanthus
ENSG00000107105	ELAVL2	100	100.000	ENSAMEG00000007555	ELAVL2	100	100.000	Ailuropoda_melanoleuca
ENSG00000107105	ELAVL2	100	95.373	ENSACIG00000010855	ELAVL2	100	95.373	Amphilophus_citrinellus
ENSG00000107105	ELAVL2	100	95.373	ENSAOCG00000019468	ELAVL2	100	95.373	Amphiprion_ocellaris
ENSG00000107105	ELAVL2	100	95.373	ENSAPEG00000023474	ELAVL2	100	95.373	Amphiprion_percula
ENSG00000107105	ELAVL2	100	95.543	ENSATEG00000018073	ELAVL2	100	95.543	Anabas_testudineus
ENSG00000107105	ELAVL2	100	97.172	ENSAPLG00000010429	ELAVL2	100	97.172	Anas_platyrhynchos
ENSG00000107105	ELAVL2	100	99.486	ENSACAG00000017521	ELAVL2	94	99.486	Anolis_carolinensis
ENSG00000107105	ELAVL2	100	100.000	ENSANAG00000032553	ELAVL2	100	99.743	Aotus_nancymaae
ENSG00000107105	ELAVL2	100	95.373	ENSACLG00000002715	ELAVL2	100	95.373	Astatotilapia_calliptera
ENSG00000107105	ELAVL2	100	95.373	ENSAMXG00000036990	ELAVL2	100	95.373	Astyanax_mexicanus
ENSG00000107105	ELAVL2	100	100.000	ENSBTAG00000046348	ELAVL2	100	100.000	Bos_taurus
ENSG00000107105	ELAVL2	100	100.000	ENSCJAG00000008064	ELAVL2	100	100.000	Callithrix_jacchus
ENSG00000107105	ELAVL2	100	100.000	ENSCAFG00000001688	ELAVL2	100	99.743	Canis_familiaris
ENSG00000107105	ELAVL2	100	100.000	ENSCAFG00020013836	ELAVL2	100	100.000	Canis_lupus_dingo
ENSG00000107105	ELAVL2	100	100.000	ENSCHIG00000025894	ELAVL2	100	100.000	Capra_hircus
ENSG00000107105	ELAVL2	100	100.000	ENSTSYG00000013066	ELAVL2	100	100.000	Carlito_syrichta
ENSG00000107105	ELAVL2	100	100.000	ENSCAPG00000003609	ELAVL2	100	93.291	Cavia_aperea
ENSG00000107105	ELAVL2	100	100.000	ENSCPOG00000010472	ELAVL2	100	99.743	Cavia_porcellus
ENSG00000107105	ELAVL2	100	100.000	ENSCCAG00000024508	ELAVL2	100	100.000	Cebus_capucinus
ENSG00000107105	ELAVL2	100	100.000	ENSCATG00000012522	ELAVL2	100	100.000	Cercocebus_atys
ENSG00000107105	ELAVL2	100	100.000	ENSCLAG00000003388	ELAVL2	100	100.000	Chinchilla_lanigera
ENSG00000107105	ELAVL2	100	100.000	ENSCSAG00000009718	ELAVL2	100	99.743	Chlorocebus_sabaeus
ENSG00000107105	ELAVL2	100	100.000	ENSCHOG00000000635	ELAVL2	80	99.476	Choloepus_hoffmanni
ENSG00000107105	ELAVL2	100	99.486	ENSCPBG00000007841	ELAVL2	100	99.486	Chrysemys_picta_bellii
ENSG00000107105	ELAVL2	100	65.217	ENSCING00000004712	-	98	60.052	Ciona_intestinalis
ENSG00000107105	ELAVL2	100	65.217	ENSCSAVG00000003440	-	99	66.773	Ciona_savignyi
ENSG00000107105	ELAVL2	100	100.000	ENSCANG00000043179	ELAVL2	100	100.000	Colobus_angolensis_palliatus
ENSG00000107105	ELAVL2	100	100.000	ENSCGRG00001024409	Elavl2	100	99.486	Cricetulus_griseus_chok1gshd
ENSG00000107105	ELAVL2	100	100.000	ENSCGRG00000000487	Elavl2	100	99.486	Cricetulus_griseus_crigri
ENSG00000107105	ELAVL2	100	95.116	ENSCSEG00000006335	elavl2	100	95.116	Cynoglossus_semilaevis
ENSG00000107105	ELAVL2	100	94.602	ENSCVAG00000013913	ELAVL2	100	94.602	Cyprinodon_variegatus
ENSG00000107105	ELAVL2	100	91.538	ENSDARG00000040732	elavl2	100	92.529	Danio_rerio
ENSG00000107105	ELAVL2	100	100.000	ENSDNOG00000035657	ELAVL2	100	100.000	Dasypus_novemcinctus
ENSG00000107105	ELAVL2	100	100.000	ENSDORG00000010437	Elavl2	100	100.000	Dipodomys_ordii
ENSG00000107105	ELAVL2	94	61.473	FBgn0086675	fne	97	61.960	Drosophila_melanogaster
ENSG00000107105	ELAVL2	83	75.817	FBgn0010263	Rbp9	82	60.753	Drosophila_melanogaster
ENSG00000107105	ELAVL2	100	100.000	ENSETEG00000006134	ELAVL2	100	99.229	Echinops_telfairi
ENSG00000107105	ELAVL2	100	83.333	ENSEBUG00000016008	elavl2	97	83.860	Eptatretus_burgeri
ENSG00000107105	ELAVL2	100	91.111	ENSEBUG00000008179	-	100	84.011	Eptatretus_burgeri
ENSG00000107105	ELAVL2	100	63.333	ENSEBUG00000000352	-	95	66.987	Eptatretus_burgeri
ENSG00000107105	ELAVL2	100	100.000	ENSEASG00005004697	ELAVL2	100	99.743	Equus_asinus_asinus
ENSG00000107105	ELAVL2	100	100.000	ENSECAG00000020142	ELAVL2	100	99.743	Equus_caballus
ENSG00000107105	ELAVL2	100	100.000	ENSEEUG00000008733	ELAVL2	100	85.090	Erinaceus_europaeus
ENSG00000107105	ELAVL2	100	96.144	ENSELUG00000010026	ELAVL2	100	96.144	Esox_lucius
ENSG00000107105	ELAVL2	100	100.000	ENSFCAG00000011976	ELAVL2	100	100.000	Felis_catus
ENSG00000107105	ELAVL2	100	97.778	ENSFALG00000007363	ELAVL2	100	97.172	Ficedula_albicollis
ENSG00000107105	ELAVL2	100	100.000	ENSFDAG00000018820	ELAVL2	100	99.486	Fukomys_damarensis
ENSG00000107105	ELAVL2	100	94.180	ENSFHEG00000010307	ELAVL2	100	91.774	Fundulus_heteroclitus
ENSG00000107105	ELAVL2	100	95.000	ENSGMOG00000011182	ELAVL2	100	95.278	Gadus_morhua
ENSG00000107105	ELAVL2	100	96.667	ENSGALG00000015799	ELAVL2	100	96.401	Gallus_gallus
ENSG00000107105	ELAVL2	100	95.373	ENSGAFG00000016517	ELAVL2	92	95.373	Gambusia_affinis
ENSG00000107105	ELAVL2	100	95.000	ENSGACG00000019484	elavl2	100	95.278	Gasterosteus_aculeatus
ENSG00000107105	ELAVL2	59	84.211	ENSGAGG00000005858	-	99	84.211	Gopherus_agassizii
ENSG00000107105	ELAVL2	100	99.486	ENSGAGG00000022382	ELAVL2	100	99.486	Gopherus_agassizii
ENSG00000107105	ELAVL2	100	100.000	ENSGGOG00000003678	ELAVL2	100	100.000	Gorilla_gorilla
ENSG00000107105	ELAVL2	100	95.373	ENSHBUG00000005968	ELAVL2	100	95.373	Haplochromis_burtoni
ENSG00000107105	ELAVL2	100	100.000	ENSHGLG00000005423	ELAVL2	100	100.000	Heterocephalus_glaber_female
ENSG00000107105	ELAVL2	100	100.000	ENSHGLG00100002344	ELAVL2	100	100.000	Heterocephalus_glaber_male
ENSG00000107105	ELAVL2	100	91.005	ENSHCOG00000005961	elavl2	100	89.203	Hippocampus_comes
ENSG00000107105	ELAVL2	100	93.333	ENSIPUG00000012337	elavl2	94	93.915	Ictalurus_punctatus
ENSG00000107105	ELAVL2	100	100.000	ENSSTOG00000007792	ELAVL2	100	99.486	Ictidomys_tridecemlineatus
ENSG00000107105	ELAVL2	100	100.000	ENSJJAG00000008247	Elavl2	100	100.000	Jaculus_jaculus
ENSG00000107105	ELAVL2	100	94.602	ENSKMAG00000006299	ELAVL2	100	94.602	Kryptolebias_marmoratus
ENSG00000107105	ELAVL2	100	95.373	ENSLBEG00000027924	ELAVL2	100	95.373	Labrus_bergylta
ENSG00000107105	ELAVL2	100	98.329	ENSLACG00000010888	ELAVL2	100	98.201	Latimeria_chalumnae
ENSG00000107105	ELAVL2	100	96.144	ENSLOCG00000012575	ELAVL2	100	96.144	Lepisosteus_oculatus
ENSG00000107105	ELAVL2	100	100.000	ENSLAFG00000009938	ELAVL2	100	100.000	Loxodonta_africana
ENSG00000107105	ELAVL2	100	100.000	ENSMFAG00000039694	ELAVL2	100	100.000	Macaca_fascicularis
ENSG00000107105	ELAVL2	100	100.000	ENSMMUG00000010038	ELAVL2	100	100.000	Macaca_mulatta
ENSG00000107105	ELAVL2	100	100.000	ENSMNEG00000032526	ELAVL2	100	100.000	Macaca_nemestrina
ENSG00000107105	ELAVL2	53	100.000	ENSMLEG00000027781	-	100	100.000	Mandrillus_leucophaeus
ENSG00000107105	ELAVL2	100	94.429	ENSMAMG00000004806	ELAVL2	100	94.429	Mastacembelus_armatus
ENSG00000107105	ELAVL2	100	95.373	ENSMZEG00005000778	ELAVL2	100	95.373	Maylandia_zebra
ENSG00000107105	ELAVL2	98	81.250	ENSMGAG00000008665	ELAVL2	85	81.250	Meleagris_gallopavo
ENSG00000107105	ELAVL2	100	100.000	ENSMAUG00000011955	Elavl2	100	99.743	Mesocricetus_auratus
ENSG00000107105	ELAVL2	100	100.000	ENSMICG00000001558	ELAVL2	100	100.000	Microcebus_murinus
ENSG00000107105	ELAVL2	100	100.000	ENSMOCG00000016960	Elavl2	100	99.743	Microtus_ochrogaster
ENSG00000107105	ELAVL2	100	94.722	ENSMMOG00000012031	ELAVL2	100	95.000	Mola_mola
ENSG00000107105	ELAVL2	100	99.486	ENSMODG00000003936	ELAVL2	100	99.486	Monodelphis_domestica
ENSG00000107105	ELAVL2	100	95.265	ENSMALG00000003411	elavl2	96	95.116	Monopterus_albus
ENSG00000107105	ELAVL2	100	100.000	MGP_CAROLIEiJ_G0026159	Elavl2	100	99.743	Mus_caroli
ENSG00000107105	ELAVL2	100	100.000	ENSMUSG00000008489	Elavl2	100	99.743	Mus_musculus
ENSG00000107105	ELAVL2	100	100.000	MGP_PahariEiJ_G0028496	Elavl2	100	99.743	Mus_pahari
ENSG00000107105	ELAVL2	100	100.000	MGP_SPRETEiJ_G0027124	Elavl2	100	99.743	Mus_spretus
ENSG00000107105	ELAVL2	100	100.000	ENSMPUG00000015967	ELAVL2	100	99.743	Mustela_putorius_furo
ENSG00000107105	ELAVL2	100	100.000	ENSMLUG00000014210	ELAVL2	98	96.561	Myotis_lucifugus
ENSG00000107105	ELAVL2	100	100.000	ENSNGAG00000014535	Elavl2	100	99.743	Nannospalax_galili
ENSG00000107105	ELAVL2	100	94.444	ENSNBRG00000023764	-	100	91.469	Neolamprologus_brichardi
ENSG00000107105	ELAVL2	100	93.333	ENSNBRG00000010284	ELAVL2	100	86.246	Neolamprologus_brichardi
ENSG00000107105	ELAVL2	100	100.000	ENSNLEG00000016382	ELAVL2	100	100.000	Nomascus_leucogenys
ENSG00000107105	ELAVL2	100	97.778	ENSMEUG00000006499	ELAVL2	100	89.717	Notamacropus_eugenii
ENSG00000107105	ELAVL2	100	100.000	ENSOPRG00000012874	ELAVL2	100	99.486	Ochotona_princeps
ENSG00000107105	ELAVL2	100	100.000	ENSODEG00000002531	ELAVL2	100	100.000	Octodon_degus
ENSG00000107105	ELAVL2	100	94.180	ENSONIG00000007552	ELAVL2	100	93.548	Oreochromis_niloticus
ENSG00000107105	ELAVL2	100	98.889	ENSOANG00000009634	ELAVL2	97	93.333	Ornithorhynchus_anatinus
ENSG00000107105	ELAVL2	100	100.000	ENSOCUG00000005891	ELAVL2	100	99.743	Oryctolagus_cuniculus
ENSG00000107105	ELAVL2	100	95.116	ENSORLG00000004217	ELAVL2	100	95.116	Oryzias_latipes
ENSG00000107105	ELAVL2	100	95.116	ENSORLG00020016040	ELAVL2	100	95.116	Oryzias_latipes_hni
ENSG00000107105	ELAVL2	100	95.116	ENSORLG00015013661	ELAVL2	100	95.116	Oryzias_latipes_hsok
ENSG00000107105	ELAVL2	100	95.116	ENSOMEG00000005178	ELAVL2	100	95.116	Oryzias_melastigma
ENSG00000107105	ELAVL2	100	100.000	ENSOGAG00000016228	ELAVL2	98	97.819	Otolemur_garnettii
ENSG00000107105	ELAVL2	100	100.000	ENSOARG00000014465	ELAVL2	100	99.743	Ovis_aries
ENSG00000107105	ELAVL2	100	100.000	ENSPPAG00000041539	ELAVL2	100	99.743	Pan_paniscus
ENSG00000107105	ELAVL2	100	100.000	ENSPPRG00000018510	ELAVL2	100	100.000	Panthera_pardus
ENSG00000107105	ELAVL2	100	100.000	ENSPTIG00000005627	ELAVL2	100	100.000	Panthera_tigris_altaica
ENSG00000107105	ELAVL2	100	100.000	ENSPTRG00000020830	ELAVL2	100	100.000	Pan_troglodytes
ENSG00000107105	ELAVL2	100	100.000	ENSPANG00000025263	ELAVL2	100	99.743	Papio_anubis
ENSG00000107105	ELAVL2	100	95.373	ENSPKIG00000001903	-	100	95.373	Paramormyrops_kingsleyae
ENSG00000107105	ELAVL2	100	95.887	ENSPKIG00000006187	ELAVL2	100	95.887	Paramormyrops_kingsleyae
ENSG00000107105	ELAVL2	100	98.889	ENSPSIG00000015330	ELAVL2	100	99.357	Pelodiscus_sinensis
ENSG00000107105	ELAVL2	100	94.167	ENSPMGG00000022018	elavl2	100	94.444	Periophthalmus_magnuspinnatus
ENSG00000107105	ELAVL2	100	100.000	ENSPEMG00000014101	Elavl2	100	99.743	Peromyscus_maniculatus_bairdii
ENSG00000107105	ELAVL2	100	99.471	ENSPCIG00000011696	ELAVL2	100	99.229	Phascolarctos_cinereus
ENSG00000107105	ELAVL2	100	95.116	ENSPFOG00000003436	ELAVL2	92	95.116	Poecilia_formosa
ENSG00000107105	ELAVL2	100	95.116	ENSPLAG00000005203	ELAVL2	100	95.000	Poecilia_latipinna
ENSG00000107105	ELAVL2	100	95.116	ENSPMEG00000021929	ELAVL2	100	91.774	Poecilia_mexicana
ENSG00000107105	ELAVL2	100	95.116	ENSPREG00000017160	ELAVL2	100	95.116	Poecilia_reticulata
ENSG00000107105	ELAVL2	100	100.000	ENSPPYG00000019166	ELAVL2	100	99.743	Pongo_abelii
ENSG00000107105	ELAVL2	100	100.000	ENSPCAG00000014998	ELAVL2	100	95.887	Procavia_capensis
ENSG00000107105	ELAVL2	100	100.000	ENSPCOG00000022819	ELAVL2	100	100.000	Propithecus_coquereli
ENSG00000107105	ELAVL2	100	100.000	ENSPVAG00000002688	ELAVL2	100	99.486	Pteropus_vampyrus
ENSG00000107105	ELAVL2	100	95.373	ENSPNYG00000001514	ELAVL2	100	95.373	Pundamilia_nyererei
ENSG00000107105	ELAVL2	100	94.859	ENSPNAG00000029068	ELAVL2	100	94.859	Pygocentrus_nattereri
ENSG00000107105	ELAVL2	100	100.000	ENSRNOG00000006853	Elavl2	100	99.486	Rattus_norvegicus
ENSG00000107105	ELAVL2	100	100.000	ENSRBIG00000029495	ELAVL2	100	100.000	Rhinopithecus_bieti
ENSG00000107105	ELAVL2	100	100.000	ENSRROG00000041782	ELAVL2	100	100.000	Rhinopithecus_roxellana
ENSG00000107105	ELAVL2	100	100.000	ENSSBOG00000028114	ELAVL2	100	99.743	Saimiri_boliviensis_boliviensis
ENSG00000107105	ELAVL2	100	98.942	ENSSHAG00000006756	ELAVL2	100	98.559	Sarcophilus_harrisii
ENSG00000107105	ELAVL2	100	94.344	ENSSFOG00015018252	elavl2	100	94.344	Scleropages_formosus
ENSG00000107105	ELAVL2	100	91.005	ENSSFOG00015001257	ELAVL2	100	90.488	Scleropages_formosus
ENSG00000107105	ELAVL2	100	95.373	ENSSMAG00000010745	ELAVL2	100	95.373	Scophthalmus_maximus
ENSG00000107105	ELAVL2	100	95.373	ENSSDUG00000008140	ELAVL2	100	95.373	Seriola_dumerili
ENSG00000107105	ELAVL2	100	95.000	ENSSLDG00000008455	ELAVL2	100	95.278	Seriola_lalandi_dorsalis
ENSG00000107105	ELAVL2	100	100.000	ENSSARG00000005702	ELAVL2	100	99.486	Sorex_araneus
ENSG00000107105	ELAVL2	100	99.471	ENSSPUG00000001246	ELAVL2	100	99.444	Sphenodon_punctatus
ENSG00000107105	ELAVL2	100	95.000	ENSSPAG00000002388	ELAVL2	100	95.278	Stegastes_partitus
ENSG00000107105	ELAVL2	100	100.000	ENSSSCG00000005130	ELAVL2	100	100.000	Sus_scrofa
ENSG00000107105	ELAVL2	100	93.122	ENSTGUG00000001349	ELAVL2	99	89.096	Taeniopygia_guttata
ENSG00000107105	ELAVL2	100	94.167	ENSTNIG00000011312	elavl2	97	94.505	Tetraodon_nigroviridis
ENSG00000107105	ELAVL2	100	100.000	ENSTBEG00000017759	ELAVL2	100	87.661	Tupaia_belangeri
ENSG00000107105	ELAVL2	100	99.721	ENSTTRG00000011656	ELAVL2	100	99.229	Tursiops_truncatus
ENSG00000107105	ELAVL2	100	100.000	ENSUAMG00000018679	ELAVL2	100	100.000	Ursus_americanus
ENSG00000107105	ELAVL2	100	100.000	ENSUMAG00000005644	ELAVL2	100	100.000	Ursus_maritimus
ENSG00000107105	ELAVL2	100	100.000	ENSVPAG00000005109	ELAVL2	100	99.486	Vicugna_pacos
ENSG00000107105	ELAVL2	100	100.000	ENSVVUG00000021291	ELAVL2	100	100.000	Vulpes_vulpes
ENSG00000107105	ELAVL2	100	96.825	ENSXETG00000009387	elavl2	100	97.315	Xenopus_tropicalis
ENSG00000107105	ELAVL2	100	95.101	ENSXCOG00000002464	ELAVL2	99	95.101	Xiphophorus_couchianus
ENSG00000107105	ELAVL2	100	95.373	ENSXMAG00000029211	ELAVL2	92	95.373	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003730	mRNA 3'-UTR binding	8158249.	TAS	Function
GO:0005515	protein binding	17289661.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006355	regulation of transcription, DNA-templated	8158249.	TAS	Process

EuRBPDB

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

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Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.