EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21187441	Provision of continuous maturation signaling to dendritic cells by RIG-I-stimulating cytosolic RNA synthesis of Sendai virus.	J Immunol	2011 Feb 1	Okano S	doi: 10.4049/jimmunol.0901641
24360797	Hepatic RIG-I predicts survival and interferon-α therapeutic response in hepatocellular carcinoma.	Cancer Cell	2014 Jan 13	Hou J	doi: 10.1016/j.ccr.2013.11.011
26910120	microRNA-34a-Upregulated Retinoic Acid-Inducible Gene-I Promotes Apoptosis and Delays Cell Cycle Transition in Cervical Cancer Cells.	DNA Cell Biol	2016 Jun	Wang JH	doi: 10.1089/dna.2015.3130
26336994	Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs.	Oncotarget	2015 Oct 6	Yuan D	doi: 10.18632/oncotarget.4869.
28057020	RNA virus receptor Rig-I monitors gut microbiota and inhibits colitis-associated colorectal cancer.	J Exp Clin Cancer Res	2017 Jan 5	Zhu H	doi: 10.1186/s13046-016-0471-3.
28940253	The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.	J Pathol	2018 Jan	Shu XS	doi: 10.1002/path.4986
29496994	Fascin1 suppresses RIG-I-like receptor signaling and interferon-β production by associating with I??B kinase (IKK) in colon cancer.	J Biol Chem	2018 Apr 27	Matsumura T	doi: 10.1074/jbc.M117.819201

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr9	32457145	Missense_Mutation	novel	D919N	0.18
BLCA	chr9	32467824	Missense_Mutation	novel	Q708L	0.08
BLCA	chr9	32500811	Missense_Mutation	NA	H79Y	0.05
BLCA	chr9	32489412	Missense_Mutation	novel	R244K	0.52
BLCA	chr9	32488169	Missense_Mutation	novel	E330Q	0.13	ResIII
BLCA	chr9	32485208	Missense_Mutation	novel	E483Q	0.4
BLCA	chr9	32492518	Missense_Mutation	novel	M148I	0.22
BLCA	chr9	32457123	Nonstop_Mutation	novel	926Sext33	0.28
BLCA	chr9	32487492	Frame_Shift_Del	novel	*Q451Lfs24**	0.12
BRCA	chr9	32487533	Missense_Mutation	NA	V438A	0.2
BRCA	chr9	32459496	Missense_Mutation	NA	H786Y	0.38
BRCA	chr9	32491386	Silent	NA	D202D	0.23
BRCA	chr9	32492526	Missense_Mutation	novel	K146Q	0.07
BRCA	chr9	32457351	Missense_Mutation	novel	P850Q	0.1
CESC	chr9	32526104	Missense_Mutation	novel	D21E	0.19
CESC	chr9	32473039	Frame_Shift_Del	novel	*P651Lfs6**	0.09
CESC	chr9	32485208	Missense_Mutation	NA	E483K	0.36
CESC	chr9	32480240	Frame_Shift_Ins	novel	D585*	0.09
CESC	chr9	32488110	Missense_Mutation	novel	Q349H	0.28	ResIII
CESC	chr9	32481409	Missense_Mutation	novel	F523L	0.37
COAD	chr9	32481342	Missense_Mutation	rs377702259	R546W	0.4
COAD	chr9	32466438	Missense_Mutation	NA	R730T	0.12
COAD	chr9	32526103	Missense_Mutation	novel	P22S	0.3
COAD	chr9	32457381	Missense_Mutation	novel	E840G	0.05
COAD	chr9	32500898	Missense_Mutation	novel	P50T	0.23
COAD	chr9	32457303	Missense_Mutation	rs751722546	R866Q	0.17
COAD	chr9	32459431	Frame_Shift_Del	novel	*K807Nfs17**	0.09
COAD	chr9	32492510	Missense_Mutation	novel	G151D	0.06
COAD	chr9	32493803	Silent	novel	L127L	0.15
COAD	chr9	32481338	Splice_Site	novel	X546_splice	0.23
COAD	chr9	32491322	Missense_Mutation	NA	E224K	0.12
COAD	chr9	32457058	3'UTR	novel		0.35
COAD	chr9	32488835	Frame_Shift_Del	NA	*K284Nfs63**	0.23	ResIII
COAD	chr9	32488081	Missense_Mutation	rs759405155	T359M	0.36	ResIII
COAD	chr9	32457202	Missense_Mutation	NA	G900R	0.1
COAD	chr9	32457188	Silent	novel	L904L	0.13
COAD	chr9	32473006	In_Frame_Del	novel	P658_L661del	0.33
COAD	chr9	32480270	Nonsense_Mutation	rs371404578	R575*	0.38
COAD	chr9	32480256	Silent	rs116612738	F579F	0.17
COAD	chr9	32489412	Missense_Mutation	rs143106649	R244I	0.18
COAD	chr9	32467875	Missense_Mutation	novel	H691R	0.07
COAD	chr9	32457322	Missense_Mutation	novel	A860T	0.31
COAD	chr9	32459464	Frame_Shift_Del	novel	*K796Nfs28**	0.2
ESCA	chr9	32459472	Nonsense_Mutation	rs760856237	Q794*	0.77
GBM	chr9	32489367	Missense_Mutation	novel	N259T	0.17	ResIII
GBM	chr9	32526243	5'UTR	novel		0.38
GBM	chr9	32488740	Missense_Mutation	novel	R316K	0.06	ResIII
GBM	chr9	32492503	Missense_Mutation	novel	E153D	0.2
GBM	chr9	32457234	Missense_Mutation	rs191688102	I889T	0.44
GBM	chr9	32457163	Frame_Shift_Ins	novel	*F913Lfs2**	0.07
HNSC	chr9	32493897	Missense_Mutation	novel	K96T	0.78
HNSC	chr9	32488814	Silent	novel	G291G	0.24
HNSC	chr9	32472996	Missense_Mutation	novel	G665S	0.17
HNSC	chr9	32493815	Silent	novel	I123I	0.51
HNSC	chr9	32500914	Missense_Mutation	novel	E44D	0.07
KIRC	chr9	32457092	3'UTR	novel		0.17
KIRC	chr9	32488011	Silent	rs151092988	P382P	0.49
KIRC	chr9	32480248	Missense_Mutation	NA	I582N	0.2
KIRP	chr9	32467855	Frame_Shift_Del	novel	*I693Qfs27**	0.4
KIRP	chr9	32466291	Frame_Shift_Del	novel	*K779Rfs45**	0.39
KIRP	chr9	32488731	Splice_Region	rs533070525		0.38
KIRP	chr9	32459422	Nonsense_Mutation	NA	C810*	0.08
KIRP	chr9	32467859	Silent	rs767862296	A696A	0.45
LIHC	chr9	32457128	Silent	novel	S924S	0.21
LIHC	chr9	32489380	Missense_Mutation	NA	M255V	0.13	ResIII
LUAD	chr9	32487953	Silent	NA	L402L	0.34
LUAD	chr9	32466355	Missense_Mutation	NA	E758Q	0.05
LUAD	chr9	32488880	Silent	novel	G269G	0.25
LUAD	chr9	32481384	Missense_Mutation	novel	S532C	0.74
LUAD	chr9	32500930	Missense_Mutation	NA	Q39L	0.18
LUAD	chr9	32480283	Silent	NA	F570F	0.11
LUAD	chr9	32500902	Missense_Mutation	novel	K48N	0.13
LUAD	chr9	32492482	Silent	NA	L160L	0.19
LUSC	chr9	32459402	Missense_Mutation	novel	A817V	0.04
LUSC	chr9	32493810	Missense_Mutation	novel	S125F	0.4
LUSC	chr9	32477064	Silent	novel	L614L	0.34
LUSC	chr9	32491367	Missense_Mutation	novel	I209V	0.43
LUSC	chr9	32488095	Missense_Mutation	NA	N354K	0.23	ResIII
LUSC	chr9	32488840	Nonsense_Mutation	novel	K283*	0.31	ResIII
LUSC	chr9	32489367	Frame_Shift_Del	novel	*N259Tfs3**	0.06	ResIII
LUSC	chr9	32500849	Missense_Mutation	novel	E66V	0.89
LUSC	chr9	32526091	Missense_Mutation	NA	L26M	0.17
LUSC	chr9	32487627	Missense_Mutation	novel	G407W	0.26	ResIII
OV	chr9	32488766	In_Frame_Del	novel	V293_K307del	0.07	ResIII
OV	chr9	32487986	Missense_Mutation	NA	L391V	0.35	ResIII
OV	chr9	32485259	Missense_Mutation	rs769162572	R466W	0.5
OV	chr9	32493811	Missense_Mutation	NA	S125P	0.35
OV	chr9	32488119	Missense_Mutation	novel	L346F	0.29	ResIII
OV	chr9	32457406	Missense_Mutation	rs567033543	T832A	0.13
PAAD	chr9	32488123	Missense_Mutation	novel	I345T	0.23	ResIII
PRAD	chr9	32457355	Missense_Mutation	novel	K849E	0.25
PRAD	chr9	32466307	Missense_Mutation	novel	A774S	0.38
PRAD	chr9	32488834	Frame_Shift_Ins	novel	*F285Ifs20**	0.41	ResIII
PRAD	chr9	32491394	Missense_Mutation	novel	L200F	0.32
READ	chr9	32493916	Missense_Mutation	NA	E90K	0.25
READ	chr9	32466355	Nonsense_Mutation	rs553716308	E758*	0.34
READ	chr9	32480317	Missense_Mutation	novel	R559Q	0.06
READ	chr9	32493820	Missense_Mutation	rs749687427	D122N	0.41
SARC	chr9	32500872	Silent	novel	L58L	0.17
SKCM	chr9	32500836	Silent	NA	F70F	0.6
SKCM	chr9	32500847	Missense_Mutation	NA	E67K	0.41
SKCM	chr9	32500877	Missense_Mutation	novel	F57L	0.13
SKCM	chr9	32493805	Silent	NA	L127L	0.14
SKCM	chr9	32500836	Silent	NA	F70F	0.36
SKCM	chr9	32487518	Missense_Mutation	NA	K443R	0.08
SKCM	chr9	32477027	Missense_Mutation	NA	E627K	0.2
SKCM	chr9	32457028	3'UTR	novel		0.53
STAD	chr9	32457004	3'UTR	novel		0.47
STAD	chr9	32493806	Missense_Mutation	novel	D126E	0.1
STAD	chr9	32487539	Missense_Mutation	rs139635230	A436V	0.33
STAD	chr9	32492460	Missense_Mutation	rs757063794	P168S	0.06
STAD	chr9	32488857	Missense_Mutation	NA	I277R	0.6	ResIII
STAD	chr9	32481368	Missense_Mutation	NA	A537V	0.2
STAD	chr9	32457029	3'UTR	novel		0.46
STAD	chr9	32481359	Frame_Shift_Del	novel	*L540Yfs21**	0.4
STAD	chr9	32459464	Frame_Shift_Del	novel	*K796Nfs28**	0.41
STAD	chr9	32488797	Missense_Mutation	rs765663574	A297V	0.18	ResIII
STAD	chr9	32492513	Missense_Mutation	novel	A150V	0.07
STAD	chr9	32457365	Silent	novel	R845R	0.33
STAD	chr9	32457296	Missense_Mutation	NA	N868K	0.09
STAD	chr9	32487521	Missense_Mutation	novel	V442A	0.33
STAD	chr9	32487590	Frame_Shift_Del	novel	*N419Tfs20**	0.24
STAD	chr9	32467895	Silent	novel	A684A	0.08
STAD	chr9	32457017	3'UTR	novel		0.12
STAD	chr9	32485237	Missense_Mutation	NA	Y473C	0.23
STAD	chr9	32526166	Translation_Start_Site	NA	M1?	0.39
THCA	chr9	32457324	Missense_Mutation	rs754726367	R859K	0.15
THYM	chr9	32477117	Missense_Mutation	novel	L597I	0.09
UCEC	chr9	32459431	Frame_Shift_Del	novel	*K807Nfs17**	0.52
UCEC	chr9	32493803	Silent	NA	L127L	0.31
UCEC	chr9	32493847	Nonsense_Mutation	NA	E113*	0.23
UCEC	chr9	32459489	Missense_Mutation	NA	K788T	0.27
UCEC	chr9	32466347	Missense_Mutation	NA	M760I	0.26
UCEC	chr9	32488819	Missense_Mutation	novel	K290Q	0.16	ResIII
UCEC	chr9	32457125	Missense_Mutation	novel	K925N	0.18
UCEC	chr9	32459493	Missense_Mutation	novel	E787K	0.11
UCEC	chr9	32488076	Missense_Mutation	NA	P361S	0.4	ResIII
UCEC	chr9	32498316	Intron	novel		0.16
UCEC	chr9	32481342	Missense_Mutation	rs377702259	R546W	0.07
UCEC	chr9	32489412	Missense_Mutation	rs143106649	R244I	0.45
UCEC	chr9	32491327	Missense_Mutation	NA	L222R	0.4
UCEC	chr9	32459456	Missense_Mutation	novel	P799H	0.35
UCEC	chr9	32457182	Silent	rs751820024	S906S	0.37
UCEC	chr9	32487538	Silent	rs146824214	A436A	0.49
UCEC	chr9	32457285	Missense_Mutation	novel	D872G	0.19
UCEC	chr9	32488889	Splice_Site	NA	X267_splice	0.16
UCEC	chr9	32491422	Splice_Site	NA	X191_splice	0.21
UCEC	chr9	32493847	Nonsense_Mutation	NA	E113*	0.21
UCEC	chr9	32467919	Silent	rs772210224	P676P	0.1
UCEC	chr9	32500828	Frame_Shift_Del	novel	*E67Vfs5**	0.32
UCEC	chr9	32457014	3'UTR	novel		0.26
UCEC	chr9	32487979	Missense_Mutation	novel	Q393L	0.34	ResIII
UCEC	chr9	32457155	Missense_Mutation	novel	K915N	0.5
UCEC	chr9	32467811	Silent	NA	V712V	0.4
UCEC	chr9	32457089	3'UTR	novel		0.22
UCEC	chr9	32477114	Nonsense_Mutation	novel	E598*	0.48
UCEC	chr9	32457409	Missense_Mutation	novel	Y831H	0.13
UCEC	chr9	32489427	Missense_Mutation	novel	S239N	0.21
UCEC	chr9	32457038	3'UTR	rs571546684		0.51
UCEC	chr9	32473013	Missense_Mutation	novel	G659D	0.48
UCEC	chr9	32487539	Missense_Mutation	rs139635230	A436V	0.42
UCEC	chr9	32480297	Missense_Mutation	novel	Y566H	0.5
UCEC	chr9	32457001	3'UTR	novel		0.4
UCEC	chr9	32466340	Missense_Mutation	novel	D763Y	0.09
UCEC	chr9	32488121	Missense_Mutation	novel	L346V	0.14	ResIII
UCEC	chr9	32493810	Missense_Mutation	novel	S125F	0.15
UCEC	chr9	32481380	Missense_Mutation	novel	R533M	0.09
UCEC	chr9	32477063	Missense_Mutation	novel	C615R	0.1
UCEC	chr9	32526090	Missense_Mutation	novel	L26P	0.16
UCEC	chr9	32477112	Missense_Mutation	NA	E598D	0.49
UCEC	chr9	32477075	Missense_Mutation	NA	L611I	0.26
UCEC	chr9	32480219	Missense_Mutation	NA	E592K	0.38
UCEC	chr9	32487945	Missense_Mutation	novel	Q404H	0.18	ResIII
UCEC	chr9	32459385	Missense_Mutation	rs755657492	V823I	0.25
UCEC	chr9	32467927	Missense_Mutation	novel	T674P	0.05
UCEC	chr9	32476999	Missense_Mutation	novel	T636I	0.05
UCEC	chr9	32481387	Nonsense_Mutation	novel	E531*	0.28
UCEC	chr9	32488011	Silent	rs151092988	P382P	0.3

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LAML	DEL	0.0052	0.24147
TGCT	DEL	0.32	7.3329e-05
THCA	DEL	0.0261	0.24038
THYM	DEL	0.0244	0.022012

Survival Analysis

Cancer	P-value	Q-value
THYM	0.021	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.0038	Kaplan-Meier Survival Analysis
MESO	0.0082	Kaplan-Meier Survival Analysis
ACC	0.037	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
PAAD	0.0028	Kaplan-Meier Survival Analysis
READ	0.04	Kaplan-Meier Survival Analysis
UCEC	0.0035	Kaplan-Meier Survival Analysis
LGG	0.00025	Kaplan-Meier Survival Analysis
THCA	0.013	Kaplan-Meier Survival Analysis
LUAD	0.038	Kaplan-Meier Survival Analysis
UVM	0.045	Kaplan-Meier Survival Analysis
OV	0.011	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000107201 (Gene tree)
Gene ID: 23586
Gene Symbol: DDX58
Alias: RIG-I|FLJ13599|DKFZp434J1111|RIG-1|RIG1
Full Name: DExD/H-box helicase 58
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 71,023 bases
Position: chr9:32,455,302-32,526,324
Accession: 19102
RBP type: canonical RBP
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000369197	ResIII	PF04851.15	6e-17	1	1
ENSP00000369213	ResIII	PF04851.15	1.1e-16	1	1
ENSP00000369197	RIG-I_C-RD	PF11648.8	6e-36	1	1
ENSP00000369213	RIG-I_C-RD	PF11648.8	9.8e-36	1	1
ENSP00000369197	DEAD	PF00270.29	8.6e-18	1	1
ENSP00000369213	DEAD	PF00270.29	1.8e-17	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25172485	Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs.	J Immunol	2014 Oct 1	Yang S	doi: 10.4049/jimmunol.1401136
19478455	Crystallization and preliminary crystallographic studies of human RIG-I in complex with double-stranded RNA.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2009 Jun 1	Moon H	doi: 10.1107/S1744309109018405
19380577	Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.	J Biol Chem	2009 Jun 26	Takahasi K	doi: 10.1074/jbc.M109.007179
21947008	Structural basis of RNA recognition and activation by innate immune receptor RIG-I.	Nature	2011 Sep 25	Jiang F	doi: 10.1038/nature10537.
20961956	Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.	Nucleic Acids Res	2011 Mar	Lu C	doi: 10.1093/nar/gkq974
26354181	IKK negatively regulates RIG-I via direct phosphorylation.	J Med Virol	2016 Apr	Zhang X	doi: 10.1002/jmv.24376
16877044	siRNA and isRNA: two edges of one sword.	Mol Ther	2006 Oct	Schlee M	-
20127681	DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.	Eur J Immunol	2010 Apr	Oshiumi H	doi: 10.1002/eji.200940203.
19587032	Role for the paramyxovirus genomic promoter in limiting host cell antiviral responses and cell killing.	J Virol	2009 Sep	Manuse MJ	doi: 10.1128/JVI.01055-09
19531363	Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5.	Arch Biochem Biophys	2009 Aug 1	Li X	doi: 10.1016/j.abb.2009.06.008
18550659	Cellular La protein shields nonsegmented negative-strand RNA viral leader RNA from RIG-I and enhances virus growth by diverse mechanisms.	J Virol	2008 Aug	Bitko V	doi: 10.1128/JVI.02762-07
18268020	Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity.	J Biol Chem	2008 Apr 4	Gee P	doi: 10.1074/jbc.M706777200
17190814	Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.	Proc Natl Acad Sci U S A	2007 Jan 9	Saito T	-
22301138	Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5.	J Virol	2012 Apr	Xing J	doi: 10.1128/JVI.06713-11
21632559	RNA helicase retinoic acid-inducible gene I as a sensor of Hantaan virus replication.	J Gen Virol	2011 Sep	Lee MH	doi: 10.1099/vir.0.032367-0
27574504	Dependence of RIG-I Nucleic Acid-Binding and ATP Hydrolysis on Activation of Type I Interferon Response.	Immune Netw	2016 Aug	Baek YM	doi: 10.4110/in.2016.16.4.249
24067967	Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein.	J Virol	2013 Dec	Kew C	doi: 10.1128/JVI.02564-13
28180316	Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding.	Nucleic Acids Res	2017 Feb 17	Fitzgerald ME	doi: 10.1093/nar/gkw816.
27651356	RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling.	MBio	2016 Sep 20	Durbin AF	doi: 10.1128/mBio.00833-16.
27625396	-	-	-	-	-
26215161	Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5.	BMC Biol	2015 Jul 28	Louber J	doi: 10.1186/s12915-015-0166-9.
26187414	A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.	Immunity	2015 Jul 21	Schuberth-Wagner C	doi: 10.1016/j.immuni.2015.06.015
26200004	A Sense of Self: RIG-I's Tolerance to Host RNA.	Immunity	2015 Jul 21	Schoggins JW	doi: 10.1016/j.immuni.2015.06.022.
29453856	Defective RNA sensing by RIG-I in severe influenza virus infection.	Clin Exp Immunol	2018 Jun	Jorgensen SE	doi: 10.1111/cei.13120
30047865	Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants.	Elife	2018 Jul 26	Lassig C	doi: 10.7554/eLife.38958.
30804210	The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response.	J Biol Chem	2019 Apr 19	Kim SS	doi: 10.1074/jbc.RA118.005868
21288362	Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling.	Virol J	2011 Feb 2	Pachler K	doi: 10.1186/1743-422X-8-48.
19374188	[Structural and functional views of the intracellular viral RNA sensor RIG-I].	Uirusu	2008 Dec	Go S	-
19224987	Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities.	J Virol	2009 May	Uzri D	doi: 10.1128/JVI.02449-08
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Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000379883	DDX58-202	4353	-	ENSP00000369213	925 (aa)	-	O95786
ENST00000379868	DDX58-201	4089	-	ENSP00000369197	722 (aa)	-	A2A376

Gene Model

Click here to download ENSG00000107201's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04064	NF-kappa B signaling pathway	KEGG
hsa04622	RIG-I-like receptor signaling pathway	KEGG
hsa04623	Cytosolic DNA-sensing pathway	KEGG
hsa05160	Hepatitis C	KEGG
hsa05161	Hepatitis B	KEGG
hsa05162	Measles	KEGG
hsa05164	Influenza A	KEGG
hsa05168	Herpes simplex virus 1 infection	KEGG
hsa05169	Epstein-Barr virus infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000107201	Psoriasis	6E-6	26626624
ENSG00000107201	Psoriasis	4E-7	25903422
ENSG00000107201	Psoriasis	4E-12	25574825
ENSG00000107201	Psoriasis	6E-9	25574825
ENSG00000107201	Menarche	2E-6	26312577
ENSG00000107201	Bone Density	2E-6	26312577

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000107201	rs11795343	9	32523739	T	Psoriasis vulgaris	26626624	NR	1.101	EFO_1001494
ENSG00000107201	rs11795343	9	32523739	T	Psoriasis	25574825	[1.155-1.226]	1.19	EFO_0000676
ENSG00000107201	rs11795343	9	32523739	?	Inflammatory skin disease	25574825			EFO_0000676
ENSG00000107201	rs10738889	9	32458055	?	Bone mineral density (spine) and age at menarche	26312577			EFO_0004703\|EFO_0007701
ENSG00000107201	rs11795343	9	32523739	T	Psoriasis	23143594		1.11	EFO_0000676

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000107201's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000107201	DDX58	96	34.667	ENSG00000115267	IFIH1	97	31.115
ENSG00000107201	DDX58	94	32.184	ENSG00000108771	DHX58	95	37.755

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000107201	DDX58	95	33.286	ENSAPOG00000017013	dhx58	98	33.286	Acanthochromis_polyacanthus
ENSG00000107201	DDX58	97	34.097	ENSAPOG00000024529	ifih1	98	31.010	Acanthochromis_polyacanthus
ENSG00000107201	DDX58	100	81.155	ENSAMEG00000003766	DDX58	100	79.699	Ailuropoda_melanoleuca
ENSG00000107201	DDX58	95	34.626	ENSAMEG00000005698	IFIH1	69	35.027	Ailuropoda_melanoleuca
ENSG00000107201	DDX58	94	31.556	ENSAMEG00000005941	DHX58	97	31.556	Ailuropoda_melanoleuca
ENSG00000107201	DDX58	94	34.410	ENSACIG00000021179	ifih1	69	34.415	Amphilophus_citrinellus
ENSG00000107201	DDX58	52	31.100	ENSACIG00000010684	dhx58	86	31.100	Amphilophus_citrinellus
ENSG00000107201	DDX58	93	32.899	ENSACIG00000010643	dhx58	97	32.899	Amphilophus_citrinellus
ENSG00000107201	DDX58	97	34.235	ENSAOCG00000014773	ifih1	98	31.199	Amphiprion_ocellaris
ENSG00000107201	DDX58	93	33.622	ENSAOCG00000016713	dhx58	97	33.622	Amphiprion_ocellaris
ENSG00000107201	DDX58	93	33.478	ENSAPEG00000004817	dhx58	97	33.478	Amphiprion_percula
ENSG00000107201	DDX58	97	34.235	ENSAPEG00000018872	ifih1	98	31.199	Amphiprion_percula
ENSG00000107201	DDX58	94	33.238	ENSATEG00000001847	dhx58	97	33.238	Anabas_testudineus
ENSG00000107201	DDX58	94	32.959	ENSATEG00000018364	ifih1	70	32.959	Anabas_testudineus
ENSG00000107201	DDX58	99	56.006	ENSAPLG00000015091	DDX58	99	54.524	Anas_platyrhynchos
ENSG00000107201	DDX58	94	34.262	ENSAPLG00000010913	IFIH1	68	34.262	Anas_platyrhynchos
ENSG00000107201	DDX58	99	49.309	ENSACAG00000001354	DDX58	100	46.939	Anolis_carolinensis
ENSG00000107201	DDX58	93	34.789	ENSACAG00000014017	IFIH1	68	34.789	Anolis_carolinensis
ENSG00000107201	DDX58	94	32.046	ENSACAG00000012501	DHX58	98	32.046	Anolis_carolinensis
ENSG00000107201	DDX58	97	35.302	ENSANAG00000028163	IFIH1	98	31.884	Aotus_nancymaae
ENSG00000107201	DDX58	92	94.681	ENSANAG00000031893	DDX58	99	94.681	Aotus_nancymaae
ENSG00000107201	DDX58	94	32.040	ENSANAG00000029056	DHX58	99	32.626	Aotus_nancymaae
ENSG00000107201	DDX58	94	33.240	ENSACLG00000012934	ifih1	69	33.240	Astatotilapia_calliptera
ENSG00000107201	DDX58	96	32.107	ENSACLG00000002582	dhx58	98	32.107	Astatotilapia_calliptera
ENSG00000107201	DDX58	93	33.671	ENSACLG00000002574	dhx58	97	33.671	Astatotilapia_calliptera
ENSG00000107201	DDX58	95	51.585	ENSAMXG00000015795	-	99	46.186	Astyanax_mexicanus
ENSG00000107201	DDX58	94	31.838	ENSAMXG00000030658	dhx58	96	31.838	Astyanax_mexicanus
ENSG00000107201	DDX58	94	35.211	ENSAMXG00000010023	ifih1	85	31.284	Astyanax_mexicanus
ENSG00000107201	DDX58	96	33.647	ENSBTAG00000008142	IFIH1	96	30.267	Bos_taurus
ENSG00000107201	DDX58	99	80.854	ENSBTAG00000003366	DDX58	91	80.323	Bos_taurus
ENSG00000107201	DDX58	94	31.746	ENSBTAG00000046580	DHX58	98	31.746	Bos_taurus
ENSG00000107201	DDX58	97	35.171	ENSCJAG00000005956	IFIH1	98	31.691	Callithrix_jacchus
ENSG00000107201	DDX58	94	31.753	ENSCJAG00000014852	DHX58	97	31.753	Callithrix_jacchus
ENSG00000107201	DDX58	100	94.875	ENSCJAG00000007741	DDX58	100	94.270	Callithrix_jacchus
ENSG00000107201	DDX58	94	32.612	ENSCAFG00000015720	DHX58	97	32.612	Canis_familiaris
ENSG00000107201	DDX58	99	82.621	ENSCAFG00000001807	DDX58	99	81.701	Canis_familiaris
ENSG00000107201	DDX58	96	34.483	ENSCAFG00000010438	IFIH1	70	34.748	Canis_familiaris
ENSG00000107201	DDX58	94	32.518	ENSCAFG00020013642	DHX58	99	33.473	Canis_lupus_dingo
ENSG00000107201	DDX58	96	34.483	ENSCAFG00020004329	IFIH1	97	31.814	Canis_lupus_dingo
ENSG00000107201	DDX58	100	81.981	ENSCAFG00020014567	DDX58	98	81.096	Canis_lupus_dingo
ENSG00000107201	DDX58	99	80.165	ENSCHIG00000025883	DDX58	98	79.570	Capra_hircus
ENSG00000107201	DDX58	96	34.091	ENSCHIG00000019848	IFIH1	96	30.875	Capra_hircus
ENSG00000107201	DDX58	94	31.178	ENSCHIG00000017011	DHX58	98	31.178	Capra_hircus
ENSG00000107201	DDX58	92	34.583	ENSTSYG00000005900	IFIH1	97	31.176	Carlito_syrichta
ENSG00000107201	DDX58	100	85.734	ENSTSYG00000004200	DDX58	100	84.881	Carlito_syrichta
ENSG00000107201	DDX58	50	30.423	ENSTSYG00000032842	-	95	30.423	Carlito_syrichta
ENSG00000107201	DDX58	82	31.639	ENSCAPG00000016521	DHX58	99	31.475	Cavia_aperea
ENSG00000107201	DDX58	100	60.246	ENSCAPG00000007816	DDX58	100	59.133	Cavia_aperea
ENSG00000107201	DDX58	95	33.649	ENSCAPG00000009502	IFIH1	97	32.999	Cavia_aperea
ENSG00000107201	DDX58	96	34.048	ENSCPOG00000007154	IFIH1	97	31.465	Cavia_porcellus
ENSG00000107201	DDX58	100	78.255	ENSCPOG00000001598	DDX58	100	76.998	Cavia_porcellus
ENSG00000107201	DDX58	94	31.313	ENSCPOG00000023721	DHX58	97	31.169	Cavia_porcellus
ENSG00000107201	DDX58	94	31.897	ENSCCAG00000022542	DHX58	97	31.897	Cebus_capucinus
ENSG00000107201	DDX58	97	35.039	ENSCCAG00000027248	IFIH1	98	31.594	Cebus_capucinus
ENSG00000107201	DDX58	100	93.213	ENSCCAG00000036752	DDX58	100	93.189	Cebus_capucinus
ENSG00000107201	DDX58	100	96.973	ENSCATG00000040246	DDX58	100	96.973	Cercocebus_atys
ENSG00000107201	DDX58	96	34.672	ENSCATG00000032062	IFIH1	97	31.146	Cercocebus_atys
ENSG00000107201	DDX58	94	32.328	ENSCATG00000043180	DHX58	96	35.514	Cercocebus_atys
ENSG00000107201	DDX58	98	31.342	ENSCLAG00000008509	IFIH1	97	31.342	Chinchilla_lanigera
ENSG00000107201	DDX58	100	77.147	ENSCLAG00000002351	DDX58	100	76.142	Chinchilla_lanigera
ENSG00000107201	DDX58	94	31.412	ENSCLAG00000013960	DHX58	97	31.556	Chinchilla_lanigera
ENSG00000107201	DDX58	96	34.672	ENSCSAG00000015614	IFIH1	97	31.109	Chlorocebus_sabaeus
ENSG00000107201	DDX58	94	32.184	ENSCSAG00000003082	DHX58	97	32.184	Chlorocebus_sabaeus
ENSG00000107201	DDX58	100	96.541	ENSCSAG00000009834	DDX58	100	96.541	Chlorocebus_sabaeus
ENSG00000107201	DDX58	99	74.483	ENSCHOG00000009019	DDX58	93	74.365	Choloepus_hoffmanni
ENSG00000107201	DDX58	90	32.684	ENSCPBG00000006804	DHX58	95	32.684	Chrysemys_picta_bellii
ENSG00000107201	DDX58	99	58.832	ENSCPBG00000008101	DDX58	99	56.821	Chrysemys_picta_bellii
ENSG00000107201	DDX58	94	34.521	ENSCPBG00000026441	IFIH1	69	34.530	Chrysemys_picta_bellii
ENSG00000107201	DDX58	91	31.471	ENSCING00000009744	-	97	31.471	Ciona_intestinalis
ENSG00000107201	DDX58	94	31.897	ENSCANG00000031041	DHX58	97	31.897	Colobus_angolensis_palliatus
ENSG00000107201	DDX58	92	35.466	ENSCANG00000031775	IFIH1	97	31.176	Colobus_angolensis_palliatus
ENSG00000107201	DDX58	100	96.973	ENSCANG00000031971	DDX58	100	96.973	Colobus_angolensis_palliatus
ENSG00000107201	DDX58	99	79.612	ENSCGRG00001024123	Ddx58	99	79.027	Cricetulus_griseus_chok1gshd
ENSG00000107201	DDX58	94	34.600	ENSCGRG00001024740	Ifih1	96	31.166	Cricetulus_griseus_chok1gshd
ENSG00000107201	DDX58	94	32.756	ENSCGRG00001010336	Dhx58	97	32.756	Cricetulus_griseus_chok1gshd
ENSG00000107201	DDX58	94	34.600	ENSCGRG00000010637	Ifih1	96	31.166	Cricetulus_griseus_crigri
ENSG00000107201	DDX58	99	70.645	ENSCGRG00000003581	Ddx58	99	70.645	Cricetulus_griseus_crigri
ENSG00000107201	DDX58	94	32.756	ENSCGRG00000008364	Dhx58	97	32.756	Cricetulus_griseus_crigri
ENSG00000107201	DDX58	93	31.205	ENSCSEG00000021382	dhx58	96	31.205	Cynoglossus_semilaevis
ENSG00000107201	DDX58	94	32.821	ENSCSEG00000010056	ifih1	90	30.796	Cynoglossus_semilaevis
ENSG00000107201	DDX58	94	34.262	ENSCVAG00000002089	ifih1	95	31.217	Cyprinodon_variegatus
ENSG00000107201	DDX58	95	33.906	ENSCVAG00000009503	dhx58	98	33.906	Cyprinodon_variegatus
ENSG00000107201	DDX58	99	30.276	ENSDARG00000018553	ifih1	97	35.203	Danio_rerio
ENSG00000107201	DDX58	94	33.333	ENSDARG00000089463	dhx58	99	34.186	Danio_rerio
ENSG00000107201	DDX58	73	30.115	ENSDNOG00000043127	DHX58	97	30.115	Dasypus_novemcinctus
ENSG00000107201	DDX58	100	80.220	ENSDNOG00000003968	DDX58	100	79.077	Dasypus_novemcinctus
ENSG00000107201	DDX58	96	34.441	ENSDNOG00000012100	IFIH1	93	31.841	Dasypus_novemcinctus
ENSG00000107201	DDX58	96	34.501	ENSDORG00000001907	Ifih1	97	31.884	Dipodomys_ordii
ENSG00000107201	DDX58	94	30.836	ENSDORG00000006815	Dhx58	98	30.836	Dipodomys_ordii
ENSG00000107201	DDX58	99	78.363	ENSDORG00000027625	Ddx58	99	77.670	Dipodomys_ordii
ENSG00000107201	DDX58	94	36.466	ENSEBUG00000014150	DDX58	97	36.908	Eptatretus_burgeri
ENSG00000107201	DDX58	80	34.343	ENSEBUG00000012092	IFIH1	89	34.343	Eptatretus_burgeri
ENSG00000107201	DDX58	94	32.281	ENSEBUG00000007527	dhx58	99	31.019	Eptatretus_burgeri
ENSG00000107201	DDX58	93	31.250	ENSEASG00005009112	DHX58	97	31.178	Equus_asinus_asinus
ENSG00000107201	DDX58	100	82.393	ENSEASG00005004589	DDX58	91	81.633	Equus_asinus_asinus
ENSG00000107201	DDX58	90	31.118	ENSEASG00005022976	IFIH1	99	31.118	Equus_asinus_asinus
ENSG00000107201	DDX58	99	82.507	ENSECAG00000021989	DDX58	99	81.971	Equus_caballus
ENSG00000107201	DDX58	94	34.563	ENSECAG00000007881	IFIH1	95	31.682	Equus_caballus
ENSG00000107201	DDX58	93	31.433	ENSECAG00000011439	DHX58	97	31.304	Equus_caballus
ENSG00000107201	DDX58	93	34.444	ENSEEUG00000005153	IFIH1	68	34.722	Erinaceus_europaeus
ENSG00000107201	DDX58	86	76.596	ENSEEUG00000015254	DDX58	86	76.596	Erinaceus_europaeus
ENSG00000107201	DDX58	84	42.540	ENSELUG00000005444	-	95	42.540	Esox_lucius
ENSG00000107201	DDX58	94	33.761	ENSELUG00000018439	dhx58	97	33.761	Esox_lucius
ENSG00000107201	DDX58	94	32.418	ENSELUG00000019690	ifih1	74	32.548	Esox_lucius
ENSG00000107201	DDX58	100	84.319	ENSFCAG00000001294	DDX58	100	82.492	Felis_catus
ENSG00000107201	DDX58	96	34.441	ENSFCAG00000023951	IFIH1	70	34.441	Felis_catus
ENSG00000107201	DDX58	94	33.141	ENSFCAG00000002145	DHX58	96	33.141	Felis_catus
ENSG00000107201	DDX58	99	55.989	ENSFALG00000001146	DDX58	99	54.732	Ficedula_albicollis
ENSG00000107201	DDX58	87	32.198	ENSFALG00000000653	DHX58	97	32.198	Ficedula_albicollis
ENSG00000107201	DDX58	94	34.807	ENSFALG00000000721	IFIH1	68	34.807	Ficedula_albicollis
ENSG00000107201	DDX58	94	31.077	ENSFDAG00000018042	DHX58	94	30.979	Fukomys_damarensis
ENSG00000107201	DDX58	72	77.735	ENSFDAG00000011958	-	100	77.735	Fukomys_damarensis
ENSG00000107201	DDX58	93	33.379	ENSFDAG00000013122	IFIH1	93	30.660	Fukomys_damarensis
ENSG00000107201	DDX58	94	35.294	ENSFHEG00000022714	ifih1	95	31.983	Fundulus_heteroclitus
ENSG00000107201	DDX58	95	34.659	ENSFHEG00000012195	dhx58	98	34.659	Fundulus_heteroclitus
ENSG00000107201	DDX58	93	31.772	ENSGMOG00000015145	dhx58	97	31.772	Gadus_morhua
ENSG00000107201	DDX58	93	33.048	ENSGMOG00000014790	ifih1	68	33.048	Gadus_morhua
ENSG00000107201	DDX58	96	33.691	ENSGALG00000041192	IFIH1	65	33.691	Gallus_gallus
ENSG00000107201	DDX58	93	32.023	ENSGALG00000023821	DHX58	97	32.023	Gallus_gallus
ENSG00000107201	DDX58	94	35.162	ENSGAFG00000007593	ifih1	95	31.707	Gambusia_affinis
ENSG00000107201	DDX58	93	33.864	ENSGAFG00000000986	dhx58	98	33.864	Gambusia_affinis
ENSG00000107201	DDX58	93	33.624	ENSGACG00000008740	dhx58	96	33.624	Gasterosteus_aculeatus
ENSG00000107201	DDX58	94	33.801	ENSGACG00000005518	ifih1	68	33.801	Gasterosteus_aculeatus
ENSG00000107201	DDX58	97	34.718	ENSGAGG00000007126	IFIH1	71	34.834	Gopherus_agassizii
ENSG00000107201	DDX58	99	58.275	ENSGAGG00000018278	DDX58	99	56.284	Gopherus_agassizii
ENSG00000107201	DDX58	90	33.234	ENSGAGG00000023270	DHX58	95	33.234	Gopherus_agassizii
ENSG00000107201	DDX58	96	34.800	ENSGGOG00000015893	IFIH1	97	31.115	Gorilla_gorilla
ENSG00000107201	DDX58	100	99.861	ENSGGOG00000016335	DDX58	100	99.784	Gorilla_gorilla
ENSG00000107201	DDX58	94	31.897	ENSGGOG00000005458	DHX58	97	31.897	Gorilla_gorilla
ENSG00000107201	DDX58	93	33.526	ENSHBUG00000001953	dhx58	97	33.526	Haplochromis_burtoni
ENSG00000107201	DDX58	96	32.532	ENSHBUG00000001963	dhx58	98	32.532	Haplochromis_burtoni
ENSG00000107201	DDX58	99	32.680	ENSHBUG00000004855	ifih1	75	32.680	Haplochromis_burtoni
ENSG00000107201	DDX58	92	32.719	ENSHGLG00000011529	DHX58	82	32.719	Heterocephalus_glaber_female
ENSG00000107201	DDX58	100	79.778	ENSHGLG00000016504	DDX58	100	78.294	Heterocephalus_glaber_female
ENSG00000107201	DDX58	96	31.841	ENSHGLG00000008772	IFIH1	93	30.739	Heterocephalus_glaber_female
ENSG00000107201	DDX58	96	31.714	ENSHGLG00100002141	IFIH1	93	30.640	Heterocephalus_glaber_male
ENSG00000107201	DDX58	100	79.778	ENSHGLG00100000205	DDX58	100	78.294	Heterocephalus_glaber_male
ENSG00000107201	DDX58	94	31.124	ENSHGLG00100009705	DHX58	97	31.124	Heterocephalus_glaber_male
ENSG00000107201	DDX58	96	31.586	ENSHCOG00000004788	dhx58	99	31.728	Hippocampus_comes
ENSG00000107201	DDX58	99	33.690	ENSHCOG00000016423	ifih1	95	30.901	Hippocampus_comes
ENSG00000107201	DDX58	94	32.272	ENSIPUG00000019893	dhx58	97	32.272	Ictalurus_punctatus
ENSG00000107201	DDX58	94	35.112	ENSIPUG00000013367	ifih1	68	35.112	Ictalurus_punctatus
ENSG00000107201	DDX58	99	47.548	ENSIPUG00000003114	ddx58	99	42.887	Ictalurus_punctatus
ENSG00000107201	DDX58	99	80.389	ENSSTOG00000006994	DDX58	99	79.523	Ictidomys_tridecemlineatus
ENSG00000107201	DDX58	96	33.512	ENSSTOG00000004953	IFIH1	97	30.315	Ictidomys_tridecemlineatus
ENSG00000107201	DDX58	94	31.169	ENSSTOG00000006524	DHX58	97	31.169	Ictidomys_tridecemlineatus
ENSG00000107201	DDX58	79	78.962	ENSJJAG00000004582	Ddx58	99	78.962	Jaculus_jaculus
ENSG00000107201	DDX58	98	31.020	ENSJJAG00000018669	Ifih1	97	31.020	Jaculus_jaculus
ENSG00000107201	DDX58	93	30.836	ENSJJAG00000000855	Dhx58	97	30.647	Jaculus_jaculus
ENSG00000107201	DDX58	95	32.956	ENSKMAG00000020096	dhx58	99	32.956	Kryptolebias_marmoratus
ENSG00000107201	DDX58	98	33.244	ENSKMAG00000014309	ifih1	98	30.325	Kryptolebias_marmoratus
ENSG00000107201	DDX58	94	32.999	ENSLBEG00000004224	dhx58	97	32.999	Labrus_bergylta
ENSG00000107201	DDX58	99	34.166	ENSLBEG00000005389	ifih1	95	31.563	Labrus_bergylta
ENSG00000107201	DDX58	98	53.073	ENSLACG00000000411	DDX58	99	50.915	Latimeria_chalumnae
ENSG00000107201	DDX58	94	30.780	ENSLACG00000011208	DHX58	98	30.780	Latimeria_chalumnae
ENSG00000107201	DDX58	94	36.740	ENSLACG00000011448	IFIH1	95	36.740	Latimeria_chalumnae
ENSG00000107201	DDX58	98	43.436	ENSLOCG00000006504	-	97	43.436	Lepisosteus_oculatus
ENSG00000107201	DDX58	95	34.758	ENSLOCG00000012582	dhx58	97	34.758	Lepisosteus_oculatus
ENSG00000107201	DDX58	99	51.791	ENSLOCG00000013422	DDX58	98	48.822	Lepisosteus_oculatus
ENSG00000107201	DDX58	94	35.154	ENSLOCG00000008460	ifih1	97	31.004	Lepisosteus_oculatus
ENSG00000107201	DDX58	92	36.155	ENSLAFG00000009997	IFIH1	67	36.155	Loxodonta_africana
ENSG00000107201	DDX58	100	80.959	ENSLAFG00000005416	DDX58	100	79.336	Loxodonta_africana
ENSG00000107201	DDX58	94	30.504	ENSLAFG00000027301	DHX58	97	30.504	Loxodonta_africana
ENSG00000107201	DDX58	96	34.672	ENSMFAG00000003848	IFIH1	97	31.109	Macaca_fascicularis
ENSG00000107201	DDX58	94	32.328	ENSMFAG00000034530	DHX58	96	35.514	Macaca_fascicularis
ENSG00000107201	DDX58	100	95.152	ENSMFAG00000045674	DDX58	100	95.152	Macaca_fascicularis
ENSG00000107201	DDX58	94	32.328	ENSMMUG00000014755	DHX58	96	35.514	Macaca_mulatta
ENSG00000107201	DDX58	100	95.784	ENSMMUG00000012442	DDX58	100	95.784	Macaca_mulatta
ENSG00000107201	DDX58	96	34.672	ENSMMUG00000003202	IFIH1	97	31.109	Macaca_mulatta
ENSG00000107201	DDX58	100	95.892	ENSMNEG00000041909	DDX58	100	95.892	Macaca_nemestrina
ENSG00000107201	DDX58	94	32.328	ENSMNEG00000043994	DHX58	96	35.514	Macaca_nemestrina
ENSG00000107201	DDX58	96	34.672	ENSMNEG00000032734	IFIH1	97	31.109	Macaca_nemestrina
ENSG00000107201	DDX58	94	32.328	ENSMLEG00000042616	DHX58	96	35.514	Mandrillus_leucophaeus
ENSG00000107201	DDX58	100	96.108	ENSMLEG00000029982	DDX58	100	96.108	Mandrillus_leucophaeus
ENSG00000107201	DDX58	96	34.806	ENSMLEG00000000107	IFIH1	70	34.806	Mandrillus_leucophaeus
ENSG00000107201	DDX58	94	33.939	ENSMAMG00000003380	ifih1	95	31.441	Mastacembelus_armatus
ENSG00000107201	DDX58	93	32.602	ENSMAMG00000022316	dhx58	96	32.602	Mastacembelus_armatus
ENSG00000107201	DDX58	93	33.815	ENSMZEG00005022742	dhx58	97	33.815	Maylandia_zebra
ENSG00000107201	DDX58	96	32.673	ENSMZEG00005022739	dhx58	98	32.673	Maylandia_zebra
ENSG00000107201	DDX58	94	33.240	ENSMZEG00005007158	ifih1	70	33.240	Maylandia_zebra
ENSG00000107201	DDX58	96	33.917	ENSMGAG00000010882	IFIH1	72	33.917	Meleagris_gallopavo
ENSG00000107201	DDX58	82	31.220	ENSMGAG00000006752	DHX58	97	31.220	Meleagris_gallopavo
ENSG00000107201	DDX58	94	32.374	ENSMAUG00000019934	Dhx58	97	32.225	Mesocricetus_auratus
ENSG00000107201	DDX58	99	79.057	ENSMAUG00000021814	Ddx58	99	74.190	Mesocricetus_auratus
ENSG00000107201	DDX58	94	33.829	ENSMICG00000005405	IFIH1	95	30.709	Microcebus_murinus
ENSG00000107201	DDX58	100	88.227	ENSMICG00000006555	DDX58	100	88.227	Microcebus_murinus
ENSG00000107201	DDX58	97	30.833	ENSMOCG00000011565	Ifih1	96	30.833	Microtus_ochrogaster
ENSG00000107201	DDX58	94	32.277	ENSMOCG00000019066	Dhx58	97	32.421	Microtus_ochrogaster
ENSG00000107201	DDX58	88	78.807	ENSMOCG00000006173	Ddx58	99	78.807	Microtus_ochrogaster
ENSG00000107201	DDX58	94	34.631	ENSMMOG00000003652	ifih1	95	30.922	Mola_mola
ENSG00000107201	DDX58	93	33.186	ENSMMOG00000020631	dhx58	96	33.186	Mola_mola
ENSG00000107201	DDX58	99	30.179	ENSMODG00000005628	IFIH1	98	30.179	Monodelphis_domestica
ENSG00000107201	DDX58	94	31.358	ENSMODG00000014782	DHX58	96	31.358	Monodelphis_domestica
ENSG00000107201	DDX58	93	33.721	ENSMALG00000006556	dhx58	97	33.721	Monopterus_albus
ENSG00000107201	DDX58	98	33.950	ENSMALG00000015489	ifih1	98	30.589	Monopterus_albus
ENSG00000107201	DDX58	96	31.661	MGP_CAROLIEiJ_G0023594	Ifih1	95	31.661	Mus_caroli
ENSG00000107201	DDX58	94	33.237	MGP_CAROLIEiJ_G0017181	Dhx58	97	33.237	Mus_caroli
ENSG00000107201	DDX58	99	77.917	MGP_CAROLIEiJ_G0025893	Ddx58	99	76.649	Mus_caroli
ENSG00000107201	DDX58	99	78.194	ENSMUSG00000040296	Ddx58	99	77.081	Mus_musculus
ENSG00000107201	DDX58	92	34.535	ENSMUSG00000026896	Ifih1	93	32.051	Mus_musculus
ENSG00000107201	DDX58	94	33.622	ENSMUSG00000017830	Dhx58	97	33.622	Mus_musculus
ENSG00000107201	DDX58	94	33.285	MGP_PahariEiJ_G0018311	Dhx58	97	33.285	Mus_pahari
ENSG00000107201	DDX58	99	70.000	MGP_PahariEiJ_G0024016	Ddx58	99	69.405	Mus_pahari
ENSG00000107201	DDX58	98	30.502	MGP_PahariEiJ_G0025045	Ifih1	97	30.502	Mus_pahari
ENSG00000107201	DDX58	92	34.258	MGP_SPRETEiJ_G0024516	Ifih1	93	31.624	Mus_spretus
ENSG00000107201	DDX58	94	33.622	MGP_SPRETEiJ_G0018024	Dhx58	97	33.622	Mus_spretus
ENSG00000107201	DDX58	99	77.778	MGP_SPRETEiJ_G0026842	Ddx58	99	76.541	Mus_spretus
ENSG00000107201	DDX58	93	80.560	ENSMPUG00000004319	DDX58	91	79.882	Mustela_putorius_furo
ENSG00000107201	DDX58	94	32.853	ENSMPUG00000010568	DHX58	97	32.853	Mustela_putorius_furo
ENSG00000107201	DDX58	96	34.840	ENSMPUG00000000564	IFIH1	70	35.372	Mustela_putorius_furo
ENSG00000107201	DDX58	92	34.626	ENSMLUG00000009505	IFIH1	96	30.754	Myotis_lucifugus
ENSG00000107201	DDX58	99	81.981	ENSMLUG00000003041	DDX58	100	81.633	Myotis_lucifugus
ENSG00000107201	DDX58	94	31.457	ENSMLUG00000012001	DHX58	97	31.457	Myotis_lucifugus
ENSG00000107201	DDX58	100	78.393	ENSNGAG00000003642	Ddx58	100	77.754	Nannospalax_galili
ENSG00000107201	DDX58	98	30.967	ENSNGAG00000012752	Ifih1	97	30.967	Nannospalax_galili
ENSG00000107201	DDX58	93	31.936	ENSNGAG00000017107	Dhx58	96	32.277	Nannospalax_galili
ENSG00000107201	DDX58	96	32.390	ENSNBRG00000018263	dhx58	98	32.390	Neolamprologus_brichardi
ENSG00000107201	DDX58	93	33.817	ENSNBRG00000018515	dhx58	96	33.817	Neolamprologus_brichardi
ENSG00000107201	DDX58	94	33.801	ENSNBRG00000014585	ifih1	95	30.526	Neolamprologus_brichardi
ENSG00000107201	DDX58	98	31.655	ENSNLEG00000026782	IFIH1	97	31.655	Nomascus_leucogenys
ENSG00000107201	DDX58	83	86.644	ENSNLEG00000034971	-	95	86.644	Nomascus_leucogenys
ENSG00000107201	DDX58	92	30.362	ENSMEUG00000003310	IFIH1	68	30.362	Notamacropus_eugenii
ENSG00000107201	DDX58	94	33.671	ENSMEUG00000005569	DHX58	99	33.671	Notamacropus_eugenii
ENSG00000107201	DDX58	86	65.979	ENSMEUG00000011210	-	81	65.979	Notamacropus_eugenii
ENSG00000107201	DDX58	94	32.319	ENSOPRG00000000753	DHX58	97	32.319	Ochotona_princeps
ENSG00000107201	DDX58	88	69.704	ENSOPRG00000016806	-	79	69.697	Ochotona_princeps
ENSG00000107201	DDX58	76	32.776	ENSOPRG00000015760	IFIH1	57	32.776	Ochotona_princeps
ENSG00000107201	DDX58	96	33.869	ENSODEG00000013586	IFIH1	96	31.276	Octodon_degus
ENSG00000107201	DDX58	100	77.424	ENSODEG00000015750	DDX58	100	76.458	Octodon_degus
ENSG00000107201	DDX58	94	31.556	ENSODEG00000017902	DHX58	97	31.556	Octodon_degus
ENSG00000107201	DDX58	94	33.566	ENSONIG00000008901	ifih1	69	33.566	Oreochromis_niloticus
ENSG00000107201	DDX58	99	63.764	ENSOANG00000012131	DDX58	99	61.814	Ornithorhynchus_anatinus
ENSG00000107201	DDX58	86	36.157	ENSOANG00000006194	IFIH1	81	32.426	Ornithorhynchus_anatinus
ENSG00000107201	DDX58	94	32.319	ENSOCUG00000013278	DHX58	97	32.319	Oryctolagus_cuniculus
ENSG00000107201	DDX58	100	79.086	ENSOCUG00000004710	DDX58	100	78.196	Oryctolagus_cuniculus
ENSG00000107201	DDX58	92	35.794	ENSOCUG00000002863	IFIH1	94	31.864	Oryctolagus_cuniculus
ENSG00000107201	DDX58	95	32.528	ENSORLG00000003825	dhx58	97	32.518	Oryzias_latipes
ENSG00000107201	DDX58	98	33.869	ENSORLG00000016902	ifih1	98	31.552	Oryzias_latipes
ENSG00000107201	DDX58	95	32.244	ENSORLG00020008521	dhx58	97	32.230	Oryzias_latipes_hni
ENSG00000107201	DDX58	98	33.869	ENSORLG00020022369	ifih1	98	31.452	Oryzias_latipes_hni
ENSG00000107201	DDX58	95	32.244	ENSORLG00015022015	dhx58	97	32.230	Oryzias_latipes_hsok
ENSG00000107201	DDX58	98	33.869	ENSORLG00015017957	ifih1	98	31.452	Oryzias_latipes_hsok
ENSG00000107201	DDX58	93	33.906	ENSOMEG00000023054	dhx58	99	33.906	Oryzias_melastigma
ENSG00000107201	DDX58	99	31.420	ENSOMEG00000002513	ifih1	98	31.521	Oryzias_melastigma
ENSG00000107201	DDX58	74	33.028	ENSOMEG00000023026	dhx58	95	33.028	Oryzias_melastigma
ENSG00000107201	DDX58	100	85.180	ENSOGAG00000010536	DDX58	100	84.449	Otolemur_garnettii
ENSG00000107201	DDX58	93	34.716	ENSOGAG00000012611	IFIH1	68	34.716	Otolemur_garnettii
ENSG00000107201	DDX58	93	30.636	ENSOGAG00000025321	DHX58	96	30.636	Otolemur_garnettii
ENSG00000107201	DDX58	99	79.890	ENSOARG00000014731	DDX58	98	79.355	Ovis_aries
ENSG00000107201	DDX58	96	34.137	ENSOARG00000006142	IFIH1	96	30.754	Ovis_aries
ENSG00000107201	DDX58	94	31.746	ENSOARG00000018383	DHX58	98	31.746	Ovis_aries
ENSG00000107201	DDX58	96	34.667	ENSPPAG00000038665	IFIH1	97	31.115	Pan_paniscus
ENSG00000107201	DDX58	100	99.892	ENSPPAG00000041750	DDX58	100	99.892	Pan_paniscus
ENSG00000107201	DDX58	94	32.184	ENSPPAG00000031118	DHX58	97	32.184	Pan_paniscus
ENSG00000107201	DDX58	100	84.594	ENSPPRG00000010161	DDX58	100	82.707	Panthera_pardus
ENSG00000107201	DDX58	94	32.853	ENSPPRG00000004933	DHX58	96	32.853	Panthera_pardus
ENSG00000107201	DDX58	96	34.441	ENSPPRG00000024685	IFIH1	70	34.441	Panthera_pardus
ENSG00000107201	DDX58	94	32.997	ENSPTIG00000007982	DHX58	96	32.997	Panthera_tigris_altaica
ENSG00000107201	DDX58	96	34.441	ENSPTIG00000019898	IFIH1	69	34.441	Panthera_tigris_altaica
ENSG00000107201	DDX58	100	84.594	ENSPTIG00000015345	DDX58	100	82.599	Panthera_tigris_altaica
ENSG00000107201	DDX58	100	100.000	ENSPTRG00000020844	DDX58	100	100.000	Pan_troglodytes
ENSG00000107201	DDX58	94	32.184	ENSPTRG00000009191	DHX58	97	32.184	Pan_troglodytes
ENSG00000107201	DDX58	96	34.667	ENSPTRG00000012582	IFIH1	97	31.115	Pan_troglodytes
ENSG00000107201	DDX58	94	35.238	ENSPANG00000023890	IFIH1	94	31.281	Papio_anubis
ENSG00000107201	DDX58	100	96.324	ENSPANG00000025269	DDX58	100	96.324	Papio_anubis
ENSG00000107201	DDX58	94	32.328	ENSPANG00000021475	DHX58	96	35.514	Papio_anubis
ENSG00000107201	DDX58	99	50.345	ENSPKIG00000017174	DDX58	99	47.966	Paramormyrops_kingsleyae
ENSG00000107201	DDX58	94	34.429	ENSPKIG00000020140	dhx58	97	34.789	Paramormyrops_kingsleyae
ENSG00000107201	DDX58	94	34.225	ENSPKIG00000001054	ifih1	71	34.507	Paramormyrops_kingsleyae
ENSG00000107201	DDX58	94	34.759	ENSPSIG00000007364	IFIH1	95	30.495	Pelodiscus_sinensis
ENSG00000107201	DDX58	99	58.889	ENSPSIG00000013490	DDX58	99	56.681	Pelodiscus_sinensis
ENSG00000107201	DDX58	97	31.806	ENSPMGG00000006236	ifih1	95	30.552	Periophthalmus_magnuspinnatus
ENSG00000107201	DDX58	95	33.381	ENSPMGG00000010442	dhx58	98	33.381	Periophthalmus_magnuspinnatus
ENSG00000107201	DDX58	94	32.323	ENSPEMG00000018681	Dhx58	97	32.323	Peromyscus_maniculatus_bairdii
ENSG00000107201	DDX58	94	34.328	ENSPEMG00000014586	Ifih1	93	31.045	Peromyscus_maniculatus_bairdii
ENSG00000107201	DDX58	99	79.861	ENSPEMG00000012372	Ddx58	99	79.676	Peromyscus_maniculatus_bairdii
ENSG00000107201	DDX58	78	42.660	ENSPMAG00000009697	DDX58	96	42.660	Petromyzon_marinus
ENSG00000107201	DDX58	69	31.041	ENSPMAG00000007346	-	99	31.189	Petromyzon_marinus
ENSG00000107201	DDX58	99	67.538	ENSPCIG00000029320	RIG-I	99	64.850	Phascolarctos_cinereus
ENSG00000107201	DDX58	92	34.310	ENSPCIG00000030338	IFIH1	74	34.449	Phascolarctos_cinereus
ENSG00000107201	DDX58	94	32.615	ENSPCIG00000020229	LGP2	98	32.615	Phascolarctos_cinereus
ENSG00000107201	DDX58	99	31.670	ENSPFOG00000017223	ifih1	97	31.670	Poecilia_formosa
ENSG00000107201	DDX58	94	34.483	ENSPFOG00000011777	dhx58	98	34.483	Poecilia_formosa
ENSG00000107201	DDX58	99	31.670	ENSPLAG00000000949	ifih1	97	31.670	Poecilia_latipinna
ENSG00000107201	DDX58	94	34.339	ENSPLAG00000021657	dhx58	98	34.339	Poecilia_latipinna
ENSG00000107201	DDX58	94	34.438	ENSPMEG00000011404	dhx58	98	34.438	Poecilia_mexicana
ENSG00000107201	DDX58	99	31.606	ENSPMEG00000016070	ifih1	97	31.606	Poecilia_mexicana
ENSG00000107201	DDX58	96	35.422	ENSPREG00000007796	ifih1	97	31.122	Poecilia_reticulata
ENSG00000107201	DDX58	94	34.582	ENSPREG00000010240	dhx58	98	34.582	Poecilia_reticulata
ENSG00000107201	DDX58	100	98.476	ENSPPYG00000019149	DDX58	100	98.743	Pongo_abelii
ENSG00000107201	DDX58	96	34.441	ENSPPYG00000012887	IFIH1	70	34.441	Pongo_abelii
ENSG00000107201	DDX58	67	36.278	ENSPCAG00000007680	IFIH1	86	30.947	Procavia_capensis
ENSG00000107201	DDX58	76	30.243	ENSPCAG00000016244	DHX58	86	30.243	Procavia_capensis
ENSG00000107201	DDX58	65	81.707	ENSPCAG00000016086	-	71	81.707	Procavia_capensis
ENSG00000107201	DDX58	96	33.865	ENSPCOG00000021673	IFIH1	97	30.574	Propithecus_coquereli
ENSG00000107201	DDX58	100	84.488	ENSPCOG00000027117	DDX58	99	84.488	Propithecus_coquereli
ENSG00000107201	DDX58	100	84.319	ENSPVAG00000009207	DDX58	100	83.333	Pteropus_vampyrus
ENSG00000107201	DDX58	94	31.594	ENSPVAG00000003855	DHX58	97	31.594	Pteropus_vampyrus
ENSG00000107201	DDX58	90	31.489	ENSPVAG00000002643	IFIH1	67	31.631	Pteropus_vampyrus
ENSG00000107201	DDX58	94	33.380	ENSPNYG00000002971	ifih1	94	30.083	Pundamilia_nyererei
ENSG00000107201	DDX58	93	33.965	ENSPNYG00000010782	dhx58	97	33.965	Pundamilia_nyererei
ENSG00000107201	DDX58	80	37.681	ENSPNYG00000010709	dhx58	98	37.681	Pundamilia_nyererei
ENSG00000107201	DDX58	94	32.997	ENSPNAG00000028648	dhx58	97	32.997	Pygocentrus_nattereri
ENSG00000107201	DDX58	99	34.533	ENSPNAG00000023802	ifih1	85	32.143	Pygocentrus_nattereri
ENSG00000107201	DDX58	95	50.794	ENSPNAG00000002347	-	99	45.435	Pygocentrus_nattereri
ENSG00000107201	DDX58	64	76.351	ENSRNOG00000006384	Ddx58	99	76.351	Rattus_norvegicus
ENSG00000107201	DDX58	92	34.163	ENSRNOG00000006227	Ifih1	68	34.163	Rattus_norvegicus
ENSG00000107201	DDX58	94	33.813	ENSRNOG00000018247	Dhx58	97	33.813	Rattus_norvegicus
ENSG00000107201	DDX58	94	34.789	ENSRBIG00000029188	IFIH1	98	30.915	Rhinopithecus_bieti
ENSG00000107201	DDX58	94	32.328	ENSRBIG00000028906	DHX58	96	35.514	Rhinopithecus_bieti
ENSG00000107201	DDX58	100	96.676	ENSRBIG00000040257	DDX58	100	96.676	Rhinopithecus_bieti
ENSG00000107201	DDX58	100	96.649	ENSRROG00000029512	DDX58	100	96.649	Rhinopithecus_roxellana
ENSG00000107201	DDX58	96	34.672	ENSRROG00000030959	IFIH1	97	30.882	Rhinopithecus_roxellana
ENSG00000107201	DDX58	86	31.669	ENSRROG00000035891	DHX58	96	35.514	Rhinopithecus_roxellana
ENSG00000107201	DDX58	94	31.897	ENSSBOG00000020589	DHX58	97	31.897	Saimiri_boliviensis_boliviensis
ENSG00000107201	DDX58	99	31.014	ENSSBOG00000026205	IFIH1	97	31.832	Saimiri_boliviensis_boliviensis
ENSG00000107201	DDX58	99	93.620	ENSSBOG00000030627	DDX58	99	93.506	Saimiri_boliviensis_boliviensis
ENSG00000107201	DDX58	94	33.572	ENSSHAG00000006130	DHX58	98	33.572	Sarcophilus_harrisii
ENSG00000107201	DDX58	97	30.336	ENSSHAG00000017981	IFIH1	96	30.435	Sarcophilus_harrisii
ENSG00000107201	DDX58	94	52.632	ENSSFOG00015017386	ddx58	99	47.329	Scleropages_formosus
ENSG00000107201	DDX58	94	34.685	ENSSFOG00015022705	ifih1	76	34.825	Scleropages_formosus
ENSG00000107201	DDX58	94	34.776	ENSSFOG00015023124	dhx58	97	34.776	Scleropages_formosus
ENSG00000107201	DDX58	99	30.378	ENSSMAG00000012345	ifih1	99	31.102	Scophthalmus_maximus
ENSG00000107201	DDX58	96	32.815	ENSSMAG00000007427	dhx58	99	32.815	Scophthalmus_maximus
ENSG00000107201	DDX58	98	33.862	ENSSDUG00000019000	ifih1	98	30.715	Seriola_dumerili
ENSG00000107201	DDX58	94	32.235	ENSSDUG00000022971	dhx58	97	32.235	Seriola_dumerili
ENSG00000107201	DDX58	98	33.995	ENSSLDG00000016351	ifih1	98	30.653	Seriola_lalandi_dorsalis
ENSG00000107201	DDX58	94	32.235	ENSSLDG00000017659	dhx58	97	32.235	Seriola_lalandi_dorsalis
ENSG00000107201	DDX58	92	68.538	ENSSARG00000008445	DDX58	93	68.538	Sorex_araneus
ENSG00000107201	DDX58	67	31.481	ENSSARG00000002192	DHX58	72	31.481	Sorex_araneus
ENSG00000107201	DDX58	96	33.243	ENSSPUG00000017377	IFIH1	84	30.174	Sphenodon_punctatus
ENSG00000107201	DDX58	94	32.851	ENSSPUG00000012993	DHX58	98	32.851	Sphenodon_punctatus
ENSG00000107201	DDX58	99	59.218	ENSSPUG00000002608	DDX58	99	56.606	Sphenodon_punctatus
ENSG00000107201	DDX58	99	30.031	ENSSPAG00000000528	ifih1	98	30.271	Stegastes_partitus
ENSG00000107201	DDX58	93	33.527	ENSSPAG00000006485	dhx58	97	33.527	Stegastes_partitus
ENSG00000107201	DDX58	99	79.201	ENSSSCG00000030408	DDX58	99	79.976	Sus_scrofa
ENSG00000107201	DDX58	94	32.035	ENSSSCG00000017416	DHX58	97	32.035	Sus_scrofa
ENSG00000107201	DDX58	97	31.031	ENSSSCG00000015897	IFIH1	96	31.134	Sus_scrofa
ENSG00000107201	DDX58	94	34.328	ENSTGUG00000006914	IFIH1	69	34.328	Taeniopygia_guttata
ENSG00000107201	DDX58	94	32.950	ENSTGUG00000002516	DHX58	99	32.950	Taeniopygia_guttata
ENSG00000107201	DDX58	97	55.064	ENSTGUG00000001516	DDX58	100	53.115	Taeniopygia_guttata
ENSG00000107201	DDX58	99	30.426	ENSTRUG00000001413	ifih1	97	30.426	Takifugu_rubripes
ENSG00000107201	DDX58	93	34.626	ENSTRUG00000015710	dhx58	97	34.638	Takifugu_rubripes
ENSG00000107201	DDX58	93	33.041	ENSTNIG00000011713	dhx58	95	33.041	Tetraodon_nigroviridis
ENSG00000107201	DDX58	94	33.146	ENSTNIG00000016500	ifih1	68	33.146	Tetraodon_nigroviridis
ENSG00000107201	DDX58	54	35.889	ENSTBEG00000005427	DHX58	56	35.889	Tupaia_belangeri
ENSG00000107201	DDX58	91	31.769	ENSTBEG00000005625	IFIH1	88	31.769	Tupaia_belangeri
ENSG00000107201	DDX58	94	31.511	ENSTTRG00000006650	DHX58	97	31.655	Tursiops_truncatus
ENSG00000107201	DDX58	92	31.528	ENSTTRG00000013780	IFIH1	68	31.528	Tursiops_truncatus
ENSG00000107201	DDX58	99	78.225	ENSTTRG00000016993	DDX58	99	78.316	Tursiops_truncatus
ENSG00000107201	DDX58	94	31.548	ENSUAMG00000024348	DHX58	97	31.548	Ursus_americanus
ENSG00000107201	DDX58	100	82.271	ENSUAMG00000020703	DDX58	100	80.778	Ursus_americanus
ENSG00000107201	DDX58	95	34.707	ENSUAMG00000015811	IFIH1	96	31.893	Ursus_americanus
ENSG00000107201	DDX58	93	34.959	ENSUMAG00000012031	IFIH1	95	31.663	Ursus_maritimus
ENSG00000107201	DDX58	100	81.431	ENSUMAG00000005813	DDX58	100	80.021	Ursus_maritimus
ENSG00000107201	DDX58	94	30.483	ENSUMAG00000023000	DHX58	98	30.483	Ursus_maritimus
ENSG00000107201	DDX58	100	78.393	ENSVPAG00000009880	DDX58	99	78.876	Vicugna_pacos
ENSG00000107201	DDX58	92	31.944	ENSVPAG00000010823	IFIH1	79	32.361	Vicugna_pacos
ENSG00000107201	DDX58	96	34.574	ENSVVUG00000018569	IFIH1	97	31.445	Vulpes_vulpes
ENSG00000107201	DDX58	100	81.706	ENSVVUG00000021149	DDX58	100	81.158	Vulpes_vulpes
ENSG00000107201	DDX58	94	31.250	ENSVVUG00000020914	DHX58	97	31.250	Vulpes_vulpes
ENSG00000107201	DDX58	93	33.616	ENSXETG00000013176	ifih1	67	33.616	Xenopus_tropicalis
ENSG00000107201	DDX58	94	33.141	ENSXETG00000002302	dhx58	97	33.143	Xenopus_tropicalis
ENSG00000107201	DDX58	99	51.140	ENSXETG00000009200	ddx58	99	51.140	Xenopus_tropicalis
ENSG00000107201	DDX58	98	35.207	ENSXCOG00000019338	ifih1	93	31.965	Xiphophorus_couchianus
ENSG00000107201	DDX58	97	35.142	ENSXMAG00000011536	ifih1	93	32.324	Xiphophorus_maculatus
ENSG00000107201	DDX58	94	34.339	ENSXMAG00000008899	dhx58	98	34.339	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002230	positive regulation of defense response to virus by host	19609254.	IMP	Process
GO:0002735	positive regulation of myeloid dendritic cell cytokine production	-	ISS	Process
GO:0003690	double-stranded DNA binding	-	IEA	Function
GO:0003725	double-stranded RNA binding	19576794.	IDA	Function
GO:0003725	double-stranded RNA binding	19211564.	IMP	Function
GO:0003725	double-stranded RNA binding	17079289.	TAS	Function
GO:0003727	single-stranded RNA binding	19211564.	IMP	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	16127453.16177806.16281057.17079289.17190814.17460044.18636086.18724357.19017631.19164550.19193793.19419966.20007272.20127681.20434986.20818395.21102435.21791617.21813773.21903422.22152002.22301138.22328336.22623778.23552410.23843640.23870315.24360797.24478431.27824081.30193849.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005737	cytoplasm	21102435.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005923	bicellular tight junction	19122199.	IDA	Component
GO:0008270	zinc ion binding	18243112.	IDA	Function
GO:0009597	detection of virus	17079289.	IDA	Process
GO:0009615	response to virus	21616437.	TAS	Process
GO:0010628	positive regulation of gene expression	24409285.	IDA	Process
GO:0015629	actin cytoskeleton	19122199.	IDA	Component
GO:0016032	viral process	-	IEA	Process
GO:0016579	protein deubiquitination	-	TAS	Process
GO:0030334	regulation of cell migration	19122199.	IDA	Process
GO:0031625	ubiquitin protein ligase binding	26471729.	IPI	Function
GO:0032480	negative regulation of type I interferon production	-	TAS	Process
GO:0032587	ruffle membrane	19122199.	IDA	Component
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	24409285.	IDA	Process
GO:0032727	positive regulation of interferon-alpha production	19576794.	IDA	Process
GO:0032727	positive regulation of interferon-alpha production	19609254.	IMP	Process
GO:0032728	positive regulation of interferon-beta production	17079289.	IDA	Process
GO:0032728	positive regulation of interferon-beta production	19211564.19609254.19631370.	IMP	Process
GO:0032755	positive regulation of interleukin-6 production	24409285.	IDA	Process
GO:0032757	positive regulation of interleukin-8 production	24409285.	IDA	Process
GO:0034344	regulation of type III interferon production	21616437.	TAS	Process
GO:0035549	positive regulation of interferon-beta secretion	21957149.	IMP	Process
GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	21616437.	TAS	Process
GO:0039529	RIG-I signaling pathway	19211564.	IMP	Process
GO:0042802	identical protein binding	21102435.	IPI	Function
GO:0043330	response to exogenous dsRNA	-	ISS	Process
GO:0045087	innate immune response	19609254.19631370.	IMP	Process
GO:0045087	innate immune response	-	TAS	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	17079289.	IDA	Process
GO:0051091	positive regulation of DNA-binding transcription factor activity	17079289.	IDA	Process
GO:0051607	defense response to virus	21478870.	IDA	Process
GO:0051607	defense response to virus	-	TAS	Process
GO:0060760	positive regulation of response to cytokine stimulus	21957149.	IMP	Process
GO:0071360	cellular response to exogenous dsRNA	21957149.	IMP	Process
GO:1902741	positive regulation of interferon-alpha secretion	21957149.	IMP	Process
GO:1904469	positive regulation of tumor necrosis factor secretion	21957149.	IMP	Process
GO:2000778	positive regulation of interleukin-6 secretion	21957149.	IMP	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.