EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27720713	Up-regulation of GTPBP4 in colorectal carcinoma is responsible for tumor metastasis.	Biochem Biophys Res Commun	2016 Nov 4	Yu H	doi: 10.1016/j.bbrc.2016.10.010
17210637	Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein.	Mol Cell Biol	2007 Mar	Lee H	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr10	996130	Silent	NA	L116L	0.19
BLCA	chr10	1015859	Missense_Mutation	NA	R572Q	0.43
BLCA	chr10	1017310	3'UTR	novel		0.43
BLCA	chr10	1017263	3'UTR	novel		0.27
BRCA	chr10	988464	5'UTR	NA		0.22
BRCA	chr10	1000835	Silent	rs376563095	L271L	0.14
BRCA	chr10	996109	Silent	novel	V109V	0.24
BRCA	chr10	992489	Missense_Mutation	NA	D17Y	0.38
BRCA	chr10	992527	Missense_Mutation	novel	K29N	0.08
BRCA	chr10	996202	Silent	NA	V140V	0.21
BRCA	chr10	999038	Silent	rs567535488	A199A	0.1
BRCA	chr10	1012599	Silent	rs369794717	L493L	0.07
CESC	chr10	997203	Splice_Region	novel		0.33
CESC	chr10	992608	Missense_Mutation	novel	Q56H	0.09
CESC	chr10	1015841	Missense_Mutation	rs773394843	R566Q	0.34
CESC	chr10	988451	5'UTR	novel		0.24
CESC	chr10	1000793	Silent	novel	L257L	0.22
CESC	chr10	997302	Silent	novel	I185I	0.39
CESC	chr10	996258	Intron	NA		0.38
CESC	chr10	1007023	Silent	rs767893119	C336C	0.51
CHOL	chr10	1007034	Missense_Mutation	novel	L340W	0.17
COAD	chr10	1014283	Missense_Mutation	NA	L527I	0.4
COAD	chr10	1012649	Missense_Mutation	rs372753265	R510Q	0.07
COAD	chr10	1019429	3'UTR	novel		0.24
COAD	chr10	995971	Missense_Mutation	NA	D88N	0.35
COAD	chr10	1007093	Silent	NA	L360L	0.34
COAD	chr10	1017243	3'UTR	rs369588499		0.25
COAD	chr10	988427	5'UTR	novel		0.14
COAD	chr10	1005878	Nonsense_Mutation	novel	E325*	0.06
COAD	chr10	1012582	Nonsense_Mutation	NA	R488*	0.41
COAD	chr10	1012464	Splice_Site	novel	X449_splice	0.16
COAD	chr10	1014310	Missense_Mutation	NA	D536N	0.21
COAD	chr10	996915	Intron	novel		0.45
ESCA	chr10	1015844	Missense_Mutation	novel	S567T	0.14
GBM	chr10	1015859	Missense_Mutation	NA	R572Q	0.21
GBM	chr10	1015872	Silent	novel	D576D	0.49
GBM	chr10	996125	Nonsense_Mutation	novel	R115*	0.27
GBM	chr10	1019441	3'UTR	novel		0.36
HNSC	chr10	999084	Missense_Mutation	novel	L215V	0.34
HNSC	chr10	1000721	Silent	rs138136568	R233R	0.23
HNSC	chr10	1017119	Missense_Mutation	novel	K599N	0.19
HNSC	chr10	1010508	Silent	novel	P444P	0.11
HNSC	chr10	992636	Missense_Mutation	novel	L66V	0.39
HNSC	chr10	988510	Missense_Mutation	novel	V11L	0.77
KIRC	chr10	997056	Intron	novel		0.28
KIRC	chr10	1017366	3'UTR	novel		0.13
KIRP	chr10	997290	Silent	novel	K181K	0.46
KIRP	chr10	1015820	Missense_Mutation	NA	A559D	0.34
LGG	chr10	1015859	Missense_Mutation	NA	R572Q	0.04
LGG	chr10	996157	Frame_Shift_Ins	novel	*C126Lfs44**	0.14
LIHC	chr10	1017249	3'UTR	novel		0.42
LUAD	chr10	988459	5'UTR	novel		0.28
LUAD	chr10	992535	Missense_Mutation	NA	T32N	0.18
LUAD	chr10	988491	Nonsense_Mutation	novel	Y4*	0.22
LUAD	chr10	997114	Intron	novel		0.1
LUAD	chr10	1008980	Missense_Mutation	NA	E379V	0.19
LUAD	chr10	1014287	Missense_Mutation	NA	G528V	0.17
LUAD	chr10	1000856	Silent	novel	L278L	0.2
LUAD	chr10	1017300	3'UTR	rs755735176		0.28
LUSC	chr10	988408	5'UTR	novel		0.2
LUSC	chr10	995939	Missense_Mutation	NA	P77L	0.25
LUSC	chr10	997189	Intron	novel		0.12
LUSC	chr10	1009015	Missense_Mutation	novel	E391K	0.21
LUSC	chr10	1007083	Silent	NA	V356V	0.25
LUSC	chr10	996258	Intron	NA		0.56
LUSC	chr10	997296	Missense_Mutation	NA	S183R	0.24
LUSC	chr10	1012583	Missense_Mutation	rs369802399	R488Q	0.28
LUSC	chr10	1015868	Missense_Mutation	NA	R575P	0.24
LUSC	chr10	1007026	Missense_Mutation	novel	D337E	0.27
LUSC	chr10	997250	Missense_Mutation	rs149028639	T168I	0.05
OV	chr10	1000862	Silent	NA	I280I	0.25
OV	chr10	1017322	3'UTR	novel		0.06
OV	chr10	1017323	3'UTR	novel		0.07
PAAD	chr10	1012581	Silent	novel	I487I	0.26
PRAD	chr10	999056	Silent	novel	L205L	0.3
READ	chr10	997279	Missense_Mutation	novel	N178Y	0.21
READ	chr10	996156	Missense_Mutation	rs374244248	R125H	0.16
READ	chr10	1012464	Splice_Site	novel	X449_splice	0.33
READ	chr10	1017445	3'UTR	novel		0.32
READ	chr10	1017122	Missense_Mutation	NA	M600I	0.3
SKCM	chr10	996181	Silent	NA	A133A	0.17
SKCM	chr10	1000763	Silent	novel	L247L	0.43
SKCM	chr10	1000764	Missense_Mutation	rs199736710	R248C	0.42
SKCM	chr10	1008994	Missense_Mutation	novel	R384S	0.13
SKCM	chr10	1007042	Nonsense_Mutation	rs267602345	R343*	0.09
SKCM	chr10	995980	Missense_Mutation	rs141121079	H91Y	0.41
SKCM	chr10	992636	Silent	NA	L66L	0.31
SKCM	chr10	1000764	Missense_Mutation	rs199736710	R248C	0.34
SKCM	chr10	1017158	Silent	rs367578877	H612H	0.31
SKCM	chr10	1017160	Frame_Shift_Del	novel	*V613Gfs4**	0.3
SKCM	chr10	995938	Missense_Mutation	NA	P77S	0.45
SKCM	chr10	1015817	Missense_Mutation	rs755370801	S558F	0.32
SKCM	chr10	997293	Silent	NA	S182S	0.32
SKCM	chr10	995938	Missense_Mutation	NA	P77S	0.2
SKCM	chr10	1015839	Silent	novel	A565A	0.42
SKCM	chr10	995938	Missense_Mutation	NA	P77S	0.59
SKCM	chr10	992648	Missense_Mutation	NA	P70S	0.17
SKCM	chr10	997203	Splice_Region	novel		0.9
SKCM	chr10	1009022	Missense_Mutation	rs201448915	S393F	0.65
SKCM	chr10	1015781	Missense_Mutation	novel	S546F	0.5
SKCM	chr10	997224	Silent	novel	S159S	0.47
SKCM	chr10	992569	Silent	NA	I43I	0.51
STAD	chr10	1012649	Missense_Mutation	rs372753265	R510Q	0.29
STAD	chr10	1007093	Silent	NA	L360L	0.09
STAD	chr10	1009555	Silent	novel	G406G	0.31
STAD	chr10	1012474	Nonsense_Mutation	NA	E452*	0.23
STAD	chr10	1012637	Missense_Mutation	novel	P506H	0.09
STAD	chr10	997210	Missense_Mutation	NA	R155C	0.27
THCA	chr10	1000859	Silent	NA	F279F	0.07
THCA	chr10	1014310	Missense_Mutation	NA	D536N	0.43
THCA	chr10	996122	Frame_Shift_Ins	novel	*V114Dfs52**	0.17
THCA	chr10	1000765	Missense_Mutation	novel	R248L	0.12
THYM	chr10	999088	Missense_Mutation	rs566484717	R216H	0.27
UCEC	chr10	1015859	Missense_Mutation	novel	R572L	0.08
UCEC	chr10	992642	Missense_Mutation	NA	D68Y	0.49
UCEC	chr10	1017146	Missense_Mutation	novel	E608D	0.21
UCEC	chr10	1012640	Missense_Mutation	NA	R507K	0.26
UCEC	chr10	996018	Missense_Mutation	novel	K103N	0.21
UCEC	chr10	1007096	Missense_Mutation	rs776366252	H361Y	0.25
UCEC	chr10	999051	Missense_Mutation	novel	S204P	0.08
UCEC	chr10	1007059	Missense_Mutation	NA	M348I	0.74
UCEC	chr10	1017255	3'UTR	novel		0.36
UCEC	chr10	1019504	3'UTR	novel		0.2
UCEC	chr10	996027	Silent	novel	V106V	0.27
UCEC	chr10	1007115	Missense_Mutation	novel	R367K	0.29
UCEC	chr10	996178	Silent	rs139148950	A132A	0.2
UCEC	chr10	996295	Intron	novel		0.36
UCEC	chr10	999038	Silent	rs567535488	A199A	0.31
UCEC	chr10	1015868	Missense_Mutation	rs369165113	R575H	0.4
UCEC	chr10	1012561	Nonsense_Mutation	NA	R481*	0.35
UCEC	chr10	992633	Missense_Mutation	novel	I65L	0.54
UCEC	chr10	996119	Missense_Mutation	novel	Y113H	0.25
UCEC	chr10	1015790	Missense_Mutation	novel	I549T	0.26
UCEC	chr10	1017149	Silent	rs140905340	A609A	0.35
UCEC	chr10	996174	Missense_Mutation	rs201468419	R131H	0.55
UCEC	chr10	1007123	Missense_Mutation	NA	D370N	0.31
UCEC	chr10	1005845	Nonsense_Mutation	novel	G314*	0.24
UCEC	chr10	1017121	Missense_Mutation	novel	M600R	0.38
UCEC	chr10	992512	Silent	rs764628176	S24S	0.37
UCEC	chr10	1012543	Missense_Mutation	rs752236545	E475K	0.59
UCEC	chr10	1017335	3'UTR	novel		0.39
UCEC	chr10	992523	Missense_Mutation	rs774844408	R28Q	0.3
UCEC	chr10	1010467	Nonsense_Mutation	novel	E431*	0.26	NOG1
UCEC	chr10	1000983	Silent	NA	K294K	0.08
UCEC	chr10	1009538	Missense_Mutation	novel	L401I	0.17	NOG1
UCEC	chr10	1012649	Missense_Mutation	rs372753265	R510Q	0.11
UCEC	chr10	1012582	Nonsense_Mutation	NA	R488*	0.23
UCEC	chr10	999088	Missense_Mutation	rs566484717	R216H	0.1
UCEC	chr10	1019429	3'UTR	novel		0.27
UCEC	chr10	1012649	Missense_Mutation	rs372753265	R510Q	0.5
UCEC	chr10	996391	Intron	novel		0.1
UCEC	chr10	1015806	Missense_Mutation	novel	K554N	0.17
UCEC	chr10	1019390	3'UTR	novel		0.27
UCEC	chr10	992488	Splice_Site	novel	X17_splice	0.08
UCEC	chr10	1019416	3'UTR	novel		0.34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1333	0.19593
CHOL	DEL	0.1944	0.00040262
COAD	DEL	0.122	0.050084
ESCA	DEL	0.2228	0.041463
GBM	DEL	0.7851	5.7274e-07
HNSC	DEL	0.2605	0.033155
KIRC	AMP	0.0189	0.17403
KIRC	DEL	0.0947	0.0074281
KIRP	DEL	0.0521	0.085174
LGG	AMP	0.1228	1.9574e-05
LGG	DEL	0.154	1.1681e-13
LUAD	DEL	0.1531	0.0018747
MESO	DEL	0.3103	0.088547
OV	AMP	0.399	0.00024063
PAAD	DEL	0.163	0.11332
READ	DEL	0.1333	0.189
SARC	DEL	0.4241	0.0013077
SKCM	DEL	0.4605	0.10277
STAD	DEL	0.1315	0.13903
TGCT	DEL	0.4533	0.055393

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.015	Kaplan-Meier Survival Analysis
SARC	0.031	Kaplan-Meier Survival Analysis
ACC	0.00015	Kaplan-Meier Survival Analysis
HNSC	0.039	Kaplan-Meier Survival Analysis
BRCA	0.0027	Kaplan-Meier Survival Analysis
KIRP	0.0017	Kaplan-Meier Survival Analysis
CESC	0.023	Kaplan-Meier Survival Analysis
UCEC	0.0023	Kaplan-Meier Survival Analysis
GBM	0.032	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.05	Kaplan-Meier Survival Analysis
UVM	0.034	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000107937 (Gene tree)
Gene ID: 23560
Gene Symbol: GTPBP4
Alias: CRFG|NGB|FLJ10690|FLJ10686|NOG1
Full Name: GTP binding protein 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 31,918 bases
Position: chr10:988,019-1,019,936
Accession: 21535
RBP type: canonical RBP
Summary: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000354040	NOG1	PF06858.14	1.2e-25	1	1
ENSP00000354040	MMR_HSR1	PF01926.23	4.2e-18	1	1
ENSP00000354040	NOGCT	PF08155.11	7.7e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000491261	GTPBP4-204	373	-	-	- (aa)	-	-
ENST00000360059	GTPBP4-201	756	-	ENSP00000353168	140 (aa)	-	Q5T3R7
ENST00000491635	GTPBP4-205	2220	-	-	- (aa)	-	-
ENST00000483839	GTPBP4-203	596	-	-	- (aa)	-	-
ENST00000360803	GTPBP4-202	5075	XM_024447921	ENSP00000354040	634 (aa)	XP_024303689	Q9BZE4

Gene Model

Click here to download ENSG00000107937's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000107937	rs1044261	10	1019770	T	Chronic kidney disease	26831199	[1.09-1.22]	1.15	EFO_0003884
ENSG00000107937	rs1044261	10	1019770	T	Glomerular filtration rate (creatinine)	26831199	[0.0082-0.0144] unit decrease	0.0113	EFO_0005208\|EFO_0004518

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000107937's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000107937	GTPBP4	100	94.286	ENSAPOG00000020433	gtpbp4	100	78.740	Acanthochromis_polyacanthus
ENSG00000107937	GTPBP4	100	97.857	ENSAMEG00000001845	GTPBP4	100	92.902	Ailuropoda_melanoleuca
ENSG00000107937	GTPBP4	100	94.286	ENSACIG00000018629	gtpbp4	100	79.180	Amphilophus_citrinellus
ENSG00000107937	GTPBP4	100	94.286	ENSAOCG00000000427	gtpbp4	93	82.965	Amphiprion_ocellaris
ENSG00000107937	GTPBP4	100	94.286	ENSAPEG00000002544	gtpbp4	100	83.123	Amphiprion_percula
ENSG00000107937	GTPBP4	100	95.714	ENSATEG00000012635	gtpbp4	95	83.438	Anabas_testudineus
ENSG00000107937	GTPBP4	52	80.665	ENSAPLG00000013790	-	100	80.665	Anas_platyrhynchos
ENSG00000107937	GTPBP4	100	95.000	ENSACAG00000002943	GTPBP4	100	84.543	Anolis_carolinensis
ENSG00000107937	GTPBP4	99	94.964	ENSANAG00000022188	-	99	84.177	Aotus_nancymaae
ENSG00000107937	GTPBP4	100	87.857	ENSANAG00000029209	-	100	91.040	Aotus_nancymaae
ENSG00000107937	GTPBP4	100	93.571	ENSACLG00000026330	gtpbp4	92	92.667	Astatotilapia_calliptera
ENSG00000107937	GTPBP4	100	96.429	ENSAMXG00000019771	gtpbp4	100	82.808	Astyanax_mexicanus
ENSG00000107937	GTPBP4	85	82.353	ENSBTAG00000054119	-	90	78.981	Bos_taurus
ENSG00000107937	GTPBP4	100	99.286	ENSBTAG00000014917	GTPBP4	100	93.849	Bos_taurus
ENSG00000107937	GTPBP4	99	74.638	WBGene00020297	nog-1	99	52.693	Caenorhabditis_elegans
ENSG00000107937	GTPBP4	100	100.000	ENSCJAG00000008494	-	100	97.642	Callithrix_jacchus
ENSG00000107937	GTPBP4	100	97.857	ENSCJAG00000022962	-	100	96.226	Callithrix_jacchus
ENSG00000107937	GTPBP4	100	97.857	ENSCAFG00000005536	GTPBP4	100	93.867	Canis_familiaris
ENSG00000107937	GTPBP4	100	97.857	ENSCAFG00020004307	GTPBP4	100	94.164	Canis_lupus_dingo
ENSG00000107937	GTPBP4	100	99.286	ENSCHIG00000018346	GTPBP4	100	93.849	Capra_hircus
ENSG00000107937	GTPBP4	100	100.000	ENSTSYG00000004977	GTPBP4	100	95.268	Carlito_syrichta
ENSG00000107937	GTPBP4	99	83.307	ENSCAPG00000002134	GTPBP4	99	83.307	Cavia_aperea
ENSG00000107937	GTPBP4	100	99.286	ENSCPOG00000013736	GTPBP4	100	94.953	Cavia_porcellus
ENSG00000107937	GTPBP4	100	99.286	ENSCCAG00000021627	-	92	97.156	Cebus_capucinus
ENSG00000107937	GTPBP4	100	74.132	ENSCCAG00000030115	-	100	74.132	Cebus_capucinus
ENSG00000107937	GTPBP4	100	100.000	ENSCATG00000004303	GTPBP4	100	98.107	Cercocebus_atys
ENSG00000107937	GTPBP4	100	99.286	ENSCLAG00000011323	GTPBP4	100	94.795	Chinchilla_lanigera
ENSG00000107937	GTPBP4	100	100.000	ENSCSAG00000014097	GTPBP4	100	98.265	Chlorocebus_sabaeus
ENSG00000107937	GTPBP4	100	98.571	ENSCHOG00000012602	GTPBP4	88	96.765	Choloepus_hoffmanni
ENSG00000107937	GTPBP4	100	95.714	ENSCPBG00000008398	GTPBP4	100	85.962	Chrysemys_picta_bellii
ENSG00000107937	GTPBP4	100	82.857	ENSCING00000001957	-	100	64.441	Ciona_intestinalis
ENSG00000107937	GTPBP4	100	82.857	ENSCSAVG00000009793	-	99	78.317	Ciona_savignyi
ENSG00000107937	GTPBP4	100	99.286	ENSCANG00000014168	GTPBP4	100	93.250	Colobus_angolensis_palliatus
ENSG00000107937	GTPBP4	100	99.286	ENSCGRG00001013765	Gtpbp4	100	95.584	Cricetulus_griseus_chok1gshd
ENSG00000107937	GTPBP4	100	99.286	ENSCGRG00000012171	Gtpbp4	100	95.584	Cricetulus_griseus_crigri
ENSG00000107937	GTPBP4	100	95.000	ENSCSEG00000007352	gtpbp4	100	78.076	Cynoglossus_semilaevis
ENSG00000107937	GTPBP4	100	92.857	ENSCVAG00000008993	gtpbp4	100	81.546	Cyprinodon_variegatus
ENSG00000107937	GTPBP4	100	97.143	ENSDARG00000018961	gtpbp4	100	82.650	Danio_rerio
ENSG00000107937	GTPBP4	67	92.941	ENSDNOG00000006746	GTPBP4	100	92.941	Dasypus_novemcinctus
ENSG00000107937	GTPBP4	82	100.000	ENSDORG00000010884	Gtpbp4	96	100.000	Dipodomys_ordii
ENSG00000107937	GTPBP4	99	82.014	FBgn0028473	Non1	100	58.869	Drosophila_melanogaster
ENSG00000107937	GTPBP4	100	99.286	ENSETEG00000016840	-	71	90.816	Echinops_telfairi
ENSG00000107937	GTPBP4	100	89.286	ENSEBUG00000010311	gtpbp4	99	63.738	Eptatretus_burgeri
ENSG00000107937	GTPBP4	100	98.571	ENSEASG00005019082	GTPBP4	100	94.795	Equus_asinus_asinus
ENSG00000107937	GTPBP4	100	98.571	ENSECAG00000001700	GTPBP4	100	94.795	Equus_caballus
ENSG00000107937	GTPBP4	100	97.857	ENSEEUG00000009889	GTPBP4	91	93.261	Erinaceus_europaeus
ENSG00000107937	GTPBP4	100	96.429	ENSELUG00000008578	gtpbp4	96	81.772	Esox_lucius
ENSG00000107937	GTPBP4	100	99.286	ENSFCAG00000026213	GTPBP4	100	94.795	Felis_catus
ENSG00000107937	GTPBP4	100	96.429	ENSFALG00000006971	GTPBP4	87	86.593	Ficedula_albicollis
ENSG00000107937	GTPBP4	100	99.286	ENSFDAG00000000998	GTPBP4	100	95.110	Fukomys_damarensis
ENSG00000107937	GTPBP4	100	93.571	ENSFHEG00000012922	gtpbp4	100	82.650	Fundulus_heteroclitus
ENSG00000107937	GTPBP4	100	95.714	ENSGMOG00000016090	gtpbp4	100	81.230	Gadus_morhua
ENSG00000107937	GTPBP4	100	96.429	ENSGALG00000006703	GTPBP4	100	86.120	Gallus_gallus
ENSG00000107937	GTPBP4	100	93.571	ENSGAFG00000002075	gtpbp4	100	83.123	Gambusia_affinis
ENSG00000107937	GTPBP4	100	93.571	ENSGACG00000017481	gtpbp4	100	81.703	Gasterosteus_aculeatus
ENSG00000107937	GTPBP4	100	95.714	ENSGAGG00000018689	GTPBP4	100	86.201	Gopherus_agassizii
ENSG00000107937	GTPBP4	100	99.527	ENSGGOG00000013372	GTPBP4	100	99.527	Gorilla_gorilla
ENSG00000107937	GTPBP4	100	93.571	ENSHBUG00000000192	gtpbp4	100	83.281	Haplochromis_burtoni
ENSG00000107937	GTPBP4	100	99.286	ENSHGLG00000013071	GTPBP4	100	94.637	Heterocephalus_glaber_female
ENSG00000107937	GTPBP4	100	99.286	ENSHGLG00100017850	GTPBP4	100	94.637	Heterocephalus_glaber_male
ENSG00000107937	GTPBP4	100	90.000	ENSHGLG00100002964	-	100	86.614	Heterocephalus_glaber_male
ENSG00000107937	GTPBP4	100	95.714	ENSHCOG00000011543	gtpbp4	100	82.520	Hippocampus_comes
ENSG00000107937	GTPBP4	100	95.714	ENSIPUG00000014417	GTPBP4	100	83.596	Ictalurus_punctatus
ENSG00000107937	GTPBP4	100	97.857	ENSSTOG00000010042	-	100	94.953	Ictidomys_tridecemlineatus
ENSG00000107937	GTPBP4	100	86.593	ENSSTOG00000023023	-	100	86.593	Ictidomys_tridecemlineatus
ENSG00000107937	GTPBP4	100	98.571	ENSJJAG00000010021	Gtpbp4	100	93.218	Jaculus_jaculus
ENSG00000107937	GTPBP4	100	93.571	ENSKMAG00000021705	gtpbp4	100	81.073	Kryptolebias_marmoratus
ENSG00000107937	GTPBP4	100	95.000	ENSLBEG00000021419	gtpbp4	100	81.293	Labrus_bergylta
ENSG00000107937	GTPBP4	100	95.000	ENSLACG00000001449	GTPBP4	100	83.438	Latimeria_chalumnae
ENSG00000107937	GTPBP4	100	97.143	ENSLOCG00000012279	gtpbp4	100	81.077	Lepisosteus_oculatus
ENSG00000107937	GTPBP4	100	99.286	ENSLAFG00000018578	GTPBP4	100	94.006	Loxodonta_africana
ENSG00000107937	GTPBP4	100	100.000	ENSMFAG00000046251	GTPBP4	100	97.792	Macaca_fascicularis
ENSG00000107937	GTPBP4	100	94.953	ENSMMUG00000010813	GTPBP4	100	94.953	Macaca_mulatta
ENSG00000107937	GTPBP4	100	100.000	ENSMNEG00000044366	GTPBP4	100	97.950	Macaca_nemestrina
ENSG00000107937	GTPBP4	100	99.286	ENSMLEG00000039605	GTPBP4	100	97.792	Mandrillus_leucophaeus
ENSG00000107937	GTPBP4	100	95.000	ENSMAMG00000013763	gtpbp4	92	83.912	Mastacembelus_armatus
ENSG00000107937	GTPBP4	100	93.571	ENSMZEG00005006621	gtpbp4	100	83.438	Maylandia_zebra
ENSG00000107937	GTPBP4	100	98.571	ENSMAUG00000000571	Gtpbp4	100	95.110	Mesocricetus_auratus
ENSG00000107937	GTPBP4	100	100.000	ENSMICG00000013332	GTPBP4	100	95.584	Microcebus_murinus
ENSG00000107937	GTPBP4	100	98.571	ENSMOCG00000002209	Gtpbp4	100	95.584	Microtus_ochrogaster
ENSG00000107937	GTPBP4	100	95.000	ENSMMOG00000011257	gtpbp4	100	79.180	Mola_mola
ENSG00000107937	GTPBP4	100	97.143	ENSMODG00000005978	GTPBP4	100	90.221	Monodelphis_domestica
ENSG00000107937	GTPBP4	100	95.000	ENSMALG00000012488	gtpbp4	100	82.019	Monopterus_albus
ENSG00000107937	GTPBP4	100	97.857	MGP_CAROLIEiJ_G0018215	Gtpbp4	100	93.659	Mus_caroli
ENSG00000107937	GTPBP4	100	97.857	ENSMUSG00000021149	Gtpbp4	100	94.795	Mus_musculus
ENSG00000107937	GTPBP4	100	98.571	MGP_PahariEiJ_G0019265	Gtpbp4	100	94.637	Mus_pahari
ENSG00000107937	GTPBP4	100	97.857	MGP_SPRETEiJ_G0019073	Gtpbp4	100	94.620	Mus_spretus
ENSG00000107937	GTPBP4	100	98.571	ENSMPUG00000016221	GTPBP4	100	92.845	Mustela_putorius_furo
ENSG00000107937	GTPBP4	100	99.286	ENSMLUG00000028192	GTPBP4	100	93.849	Myotis_lucifugus
ENSG00000107937	GTPBP4	100	97.857	ENSNGAG00000015364	Gtpbp4	100	94.164	Nannospalax_galili
ENSG00000107937	GTPBP4	87	82.222	ENSNBRG00000019965	gtpbp4	86	82.222	Neolamprologus_brichardi
ENSG00000107937	GTPBP4	100	100.000	ENSNLEG00000013495	GTPBP4	100	98.580	Nomascus_leucogenys
ENSG00000107937	GTPBP4	81	98.246	ENSMEUG00000016215	-	72	90.625	Notamacropus_eugenii
ENSG00000107937	GTPBP4	100	99.286	ENSOPRG00000008671	GTPBP4	86	97.844	Ochotona_princeps
ENSG00000107937	GTPBP4	100	99.286	ENSODEG00000000962	-	100	95.584	Octodon_degus
ENSG00000107937	GTPBP4	100	97.143	ENSODEG00000019152	-	100	93.375	Octodon_degus
ENSG00000107937	GTPBP4	100	94.286	ENSONIG00000017707	gtpbp4	100	83.438	Oreochromis_niloticus
ENSG00000107937	GTPBP4	100	97.143	ENSOANG00000006095	-	99	87.066	Ornithorhynchus_anatinus
ENSG00000107937	GTPBP4	100	84.615	ENSOCUG00000014716	-	100	87.071	Oryctolagus_cuniculus
ENSG00000107937	GTPBP4	100	98.571	ENSOCUG00000016120	-	100	93.218	Oryctolagus_cuniculus
ENSG00000107937	GTPBP4	100	95.000	ENSORLG00000006151	gtpbp4	100	81.861	Oryzias_latipes
ENSG00000107937	GTPBP4	100	95.000	ENSORLG00020020899	gtpbp4	100	81.861	Oryzias_latipes_hni
ENSG00000107937	GTPBP4	100	95.000	ENSORLG00015020562	gtpbp4	100	81.703	Oryzias_latipes_hsok
ENSG00000107937	GTPBP4	100	94.286	ENSOMEG00000019684	gtpbp4	100	82.019	Oryzias_melastigma
ENSG00000107937	GTPBP4	100	100.000	ENSOGAG00000011941	GTPBP4	100	96.372	Otolemur_garnettii
ENSG00000107937	GTPBP4	100	99.286	ENSOARG00000015047	GTPBP4	100	92.936	Ovis_aries
ENSG00000107937	GTPBP4	100	100.000	ENSPPAG00000042066	GTPBP4	100	99.842	Pan_paniscus
ENSG00000107937	GTPBP4	100	99.286	ENSPPRG00000009895	GTPBP4	100	94.795	Panthera_pardus
ENSG00000107937	GTPBP4	100	99.286	ENSPTIG00000008569	GTPBP4	100	94.795	Panthera_tigris_altaica
ENSG00000107937	GTPBP4	100	100.000	ENSPTRG00000002236	GTPBP4	87	99.117	Pan_troglodytes
ENSG00000107937	GTPBP4	100	99.286	ENSPANG00000023543	GTPBP4	100	97.950	Papio_anubis
ENSG00000107937	GTPBP4	100	96.429	ENSPKIG00000012301	gtpbp4	100	82.492	Paramormyrops_kingsleyae
ENSG00000107937	GTPBP4	100	96.429	ENSPSIG00000005442	GTPBP4	93	91.036	Pelodiscus_sinensis
ENSG00000107937	GTPBP4	100	95.714	ENSPMGG00000001462	gtpbp4	100	79.495	Periophthalmus_magnuspinnatus
ENSG00000107937	GTPBP4	100	97.857	ENSPEMG00000015091	-	100	94.795	Peromyscus_maniculatus_bairdii
ENSG00000107937	GTPBP4	100	88.571	ENSPEMG00000012279	-	100	69.716	Peromyscus_maniculatus_bairdii
ENSG00000107937	GTPBP4	100	92.857	ENSPMAG00000000905	gtpbp4	100	75.394	Petromyzon_marinus
ENSG00000107937	GTPBP4	100	97.143	ENSPCIG00000026082	GTPBP4	100	89.905	Phascolarctos_cinereus
ENSG00000107937	GTPBP4	100	93.571	ENSPFOG00000000026	gtpbp4	100	83.123	Poecilia_formosa
ENSG00000107937	GTPBP4	100	93.571	ENSPLAG00000002898	gtpbp4	97	83.419	Poecilia_latipinna
ENSG00000107937	GTPBP4	100	93.571	ENSPMEG00000016422	gtpbp4	100	83.281	Poecilia_mexicana
ENSG00000107937	GTPBP4	100	93.571	ENSPREG00000019870	gtpbp4	100	79.180	Poecilia_reticulata
ENSG00000107937	GTPBP4	100	100.000	ENSPPYG00000002037	GTPBP4	100	99.054	Pongo_abelii
ENSG00000107937	GTPBP4	100	100.000	ENSPCOG00000014602	-	100	89.593	Propithecus_coquereli
ENSG00000107937	GTPBP4	100	99.286	ENSPCOG00000014382	-	100	90.694	Propithecus_coquereli
ENSG00000107937	GTPBP4	100	99.286	ENSPVAG00000005882	GTPBP4	86	95.283	Pteropus_vampyrus
ENSG00000107937	GTPBP4	100	73.975	ENSPNYG00000024251	gtpbp4	100	73.975	Pundamilia_nyererei
ENSG00000107937	GTPBP4	100	96.429	ENSPNAG00000019977	gtpbp4	100	83.438	Pygocentrus_nattereri
ENSG00000107937	GTPBP4	100	97.857	ENSRNOG00000016217	Gtpbp4	100	94.182	Rattus_norvegicus
ENSG00000107937	GTPBP4	100	100.000	ENSRBIG00000028875	GTPBP4	100	97.476	Rhinopithecus_bieti
ENSG00000107937	GTPBP4	100	100.000	ENSRROG00000030798	GTPBP4	100	97.476	Rhinopithecus_roxellana
ENSG00000107937	GTPBP4	99	62.319	YPL093W	-	99	46.202	Saccharomyces_cerevisiae
ENSG00000107937	GTPBP4	100	100.000	ENSSBOG00000028421	GTPBP4	100	97.170	Saimiri_boliviensis_boliviensis
ENSG00000107937	GTPBP4	100	97.857	ENSSHAG00000014713	GTPBP4	94	89.331	Sarcophilus_harrisii
ENSG00000107937	GTPBP4	100	96.429	ENSSFOG00015003167	gtpbp4	100	82.965	Scleropages_formosus
ENSG00000107937	GTPBP4	100	94.286	ENSSMAG00000005863	gtpbp4	100	82.650	Scophthalmus_maximus
ENSG00000107937	GTPBP4	100	95.714	ENSSDUG00000006534	gtpbp4	100	82.334	Seriola_dumerili
ENSG00000107937	GTPBP4	100	95.714	ENSSLDG00000020688	gtpbp4	100	82.492	Seriola_lalandi_dorsalis
ENSG00000107937	GTPBP4	61	99.010	ENSSARG00000003409	-	79	99.010	Sorex_araneus
ENSG00000107937	GTPBP4	100	96.429	ENSSPUG00000002153	GTPBP4	100	86.278	Sphenodon_punctatus
ENSG00000107937	GTPBP4	63	72.040	ENSSPAG00000014583	gtpbp4	100	72.040	Stegastes_partitus
ENSG00000107937	GTPBP4	84	91.525	ENSSPAG00000014611	-	72	92.667	Stegastes_partitus
ENSG00000107937	GTPBP4	100	98.571	ENSSSCG00000028602	GTPBP4	100	91.640	Sus_scrofa
ENSG00000107937	GTPBP4	100	96.429	ENSTGUG00000000820	GTPBP4	100	85.669	Taeniopygia_guttata
ENSG00000107937	GTPBP4	100	95.714	ENSTRUG00000003900	gtpbp4	100	81.546	Takifugu_rubripes
ENSG00000107937	GTPBP4	100	95.714	ENSTNIG00000007992	gtpbp4	100	82.965	Tetraodon_nigroviridis
ENSG00000107937	GTPBP4	81	99.123	ENSTBEG00000003613	GTPBP4	100	79.186	Tupaia_belangeri
ENSG00000107937	GTPBP4	100	97.857	ENSTTRG00000011163	GTPBP4	100	87.969	Tursiops_truncatus
ENSG00000107937	GTPBP4	100	97.857	ENSUAMG00000013191	GTPBP4	100	93.375	Ursus_americanus
ENSG00000107937	GTPBP4	100	97.857	ENSUMAG00000016138	GTPBP4	100	92.845	Ursus_maritimus
ENSG00000107937	GTPBP4	100	98.571	ENSVVUG00000008608	GTPBP4	98	94.006	Vulpes_vulpes
ENSG00000107937	GTPBP4	100	95.714	ENSXETG00000018097	gtpbp4	100	75.976	Xenopus_tropicalis
ENSG00000107937	GTPBP4	100	93.571	ENSXCOG00000019953	gtpbp4	98	76.923	Xiphophorus_couchianus
ENSG00000107937	GTPBP4	100	93.571	ENSXMAG00000006719	gtpbp4	100	82.418	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	17210637.	IDA	Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	-	IEA	Process
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003924	GTPase activity	17210637.	IDA	Function
GO:0005515	protein binding	17210637.	IPI	Function
GO:0005525	GTP binding	17210637.	IDA	Function
GO:0005634	nucleus	21630459.	HDA	Component
GO:0005634	nucleus	17210637.	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005737	cytoplasm	17210637.	IDA	Component
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0008156	negative regulation of DNA replication	17210637.	IMP	Process
GO:0008285	negative regulation of cell proliferation	17210637.	IMP	Process
GO:0016020	membrane	16210410.19946888.	HDA	Component
GO:0022408	negative regulation of cell-cell adhesion	17210637.	IDA	Process
GO:0030336	negative regulation of cell migration	17210637.	IDA	Process
GO:0031397	negative regulation of protein ubiquitination	17210637.	IDA	Process
GO:0031965	nuclear membrane	-	IDA	Component
GO:0033342	negative regulation of collagen binding	17210637.	IMP	Process
GO:0048471	perinuclear region of cytoplasm	17210637.	IDA	Component
GO:0050821	protein stabilization	17210637.	IDA	Process

EuRBPDB

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.