EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26586793	Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers.	Carcinogenesis	2016 Jan	Arora A	doi: 10.1093/carcin/bgv163
26499077	Decreased RECQL5 correlated with disease progression of osteosarcoma.	Biochem Biophys Res Commun	2015 Nov 27	Wu J	doi: 10.1016/j.bbrc.2015.10.114
21210765	RECQL5 is an important determinant for camptothecin tolerance in human colorectal cancer cells.	Biosci Rep	2011 Oct	Wang X	doi: 10.1042/BSR20100108.
25394896	Association between RECQL5 genetic polymorphisms and susceptibility to breast cancer.	Tumour Biol	2014 Dec	He YJ	doi: 10.1007/s13277-014-2528-2
24213927	Haplotype analysis of RECQL5 gene and laryngeal cancer.	Tumour Biol	2014 Mar	Qi Y	doi: 10.1007/s13277-013-1351-5

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr17	75628963	Missense_Mutation	NA	Q820H	0.07
BLCA	chr17	75628994	Missense_Mutation	novel	G810A	0.11
BLCA	chr17	75627415	3'UTR	novel		0.31
BLCA	chr17	75627332	3'UTR	novel		0.22
BLCA	chr17	75627207	3'UTR	novel		0.5
BLCA	chr17	75631493	Missense_Mutation	rs760152507	E469K	0.41
BLCA	chr17	75627471	Missense_Mutation	NA	R976L	0.44
BLCA	chr17	75628322	Missense_Mutation	NA	D901H	0.15
BLCA	chr17	75628757	Missense_Mutation	NA	C832Y	0.11
BLCA	chr17	75629049	Missense_Mutation	NA	E792K	0.09
BLCA	chr17	75629836	Missense_Mutation	novel	D607N	0.14
BLCA	chr17	75628874	Intron	novel		0.09
BLCA	chr17	75662479	Splice_Region	novel	G257G	0.24
BLCA	chr17	75665068	Missense_Mutation	novel	L79F	0.18	ResIII
BLCA	chr17	75651200	Silent	novel	F405F	0.36
BLCA	chr17	75629114	Missense_Mutation	rs202116343	R770Q	0.39
BRCA	chr17	75628751	Missense_Mutation	NA	P834L	0.13
BRCA	chr17	75658453	Missense_Mutation	rs201204572	A332T	0.51
BRCA	chr17	75650963	Intron	novel		0.5
BRCA	chr17	75661674	Missense_Mutation	NA	R269T	0.36
BRCA	chr17	75629728	Missense_Mutation	NA	P643S	0.33
BRCA	chr17	75651200	Missense_Mutation	NA	F405L	0.18
BRCA	chr17	75627647	Missense_Mutation	NA	Q951E	0.16
BRCA	chr17	75628254	Silent	NA	L923L	0.14
BRCA	chr17	75650567	Intron	novel		0.33
BRCA	chr17	75667179	5'UTR	novel		0.25
CESC	chr17	75624881	3'Flank	NA		0.32
CESC	chr17	75625843	3'Flank	novel		0.43
CESC	chr17	75626087	3'Flank	novel		0.43
CESC	chr17	75625174	3'Flank	rs763965624		0.27
CESC	chr17	75658446	Nonsense_Mutation	NA	W334*	0.15
CESC	chr17	75628338	Silent	novel	L895L	0.33
CESC	chr17	75626158	3'Flank	novel		0.1
CESC	chr17	75628813	Intron	novel		0.13
CESC	chr17	75650644	Intron	novel		0.19
CESC	chr17	75628402	Missense_Mutation	NA	S874L	0.14
CESC	chr17	75628316	Missense_Mutation	novel	F903V	0.29
CESC	chr17	75629736	Missense_Mutation	novel	D640G	0.35
CESC	chr17	75630689	Missense_Mutation	rs746220717	R550W	0.29
CESC	chr17	75631604	Missense_Mutation	rs371987831	D432N	0.2
CESC	chr17	75623963	3'Flank	rs760833606		0.2
CESC	chr17	75628379	Missense_Mutation	NA	E882K	0.11
CESC	chr17	75650568	Intron	novel		0.27
CESC	chr17	75628379	Missense_Mutation	novel	E882Q	0.29
COAD	chr17	75627431	Silent	NA	P989P	0.33
COAD	chr17	75660955	Missense_Mutation	NA	R329M	0.1
COAD	chr17	75666471	Frame_Shift_Del	NA	*F29Lfs13**	0.28	ResIII
COAD	chr17	75629416	Silent	NA	A669A	0.26
COAD	chr17	75629259	Missense_Mutation	novel	H722Y	0.29
COAD	chr17	75630673	Missense_Mutation	rs538670883	R555Q	0.5
COAD	chr17	75651174	Intron	novel		0.69
COAD	chr17	75662705	Missense_Mutation	rs369553617	R182H	0.44
COAD	chr17	75630277	Missense_Mutation	novel	E573D	0.2
COAD	chr17	75660994	Missense_Mutation	novel	T316I	0.38
COAD	chr17	75662628	Missense_Mutation	novel	H208Y	0.56
COAD	chr17	75627460	Missense_Mutation	rs761941890	E980K	0.34
COAD	chr17	75666489	Silent	novel	V23V	0.18
COAD	chr17	75631549	Missense_Mutation	NA	S450N	0.11
COAD	chr17	75630671	Missense_Mutation	NA	L556I	0.4
COAD	chr17	75666518	Missense_Mutation	novel	R14W	0.11	ResIII
COAD	chr17	75662673	Missense_Mutation	NA	A193T	0.42
COAD	chr17	75628757	Missense_Mutation	NA	C832Y	0.22
COAD	chr17	75650597	Intron	novel		0.16
COAD	chr17	75650959	Intron	novel		0.19
COAD	chr17	75662711	Missense_Mutation	rs202162742	R180H	0.43
DLBC	chr17	75658297	Splice_Site	novel	X383_splice	0.31
ESCA	chr17	75625122	3'Flank	novel		0.14
ESCA	chr17	75625807	3'Flank	novel		0.16
ESCA	chr17	75666523	Missense_Mutation	novel	P12L	0.23	ResIII
ESCA	chr17	75630987	Silent	novel	E524E	0.91
ESCA	chr17	75666448	Missense_Mutation	novel	A37V	0.25	ResIII
GBM	chr17	75629022	Missense_Mutation	NA	P801S	0.29
GBM	chr17	75662759	Missense_Mutation	novel	Q164R	0.19
GBM	chr17	75650659	Intron	novel		0.17
GBM	chr17	75651200	Missense_Mutation	novel	F405L	0.14
GBM	chr17	75628408	Missense_Mutation	rs372355133	R872H	0.1
GBM	chr17	75650504	Intron	novel		0.25
GBM	chr17	75628331	Missense_Mutation	novel	T898P	0.19
GBM	chr17	75628332	Silent	novel	P897P	0.19
GBM	chr17	75631604	Missense_Mutation	rs371987831	D432N	0.08
GBM	chr17	75650587	Intron	novel		0.26
HNSC	chr17	75665161	Missense_Mutation	novel	V48I	0.24	ResIII
HNSC	chr17	75665066	Silent	novel	L79L	0.79
HNSC	chr17	75631235	Missense_Mutation	novel	S488F	0.21
HNSC	chr17	75651175	Intron	novel		0.04
HNSC	chr17	75661035	Missense_Mutation	novel	Q302H	0.11
HNSC	chr17	75629473	Splice_Region	novel	L650L	0.14
HNSC	chr17	75629820	Missense_Mutation	rs760851276	S612C	0.08
HNSC	chr17	75628305	Silent	rs772969250	S906S	0.12
HNSC	chr17	75658431	Missense_Mutation	novel	S339Y	0.37
HNSC	chr17	75629418	Missense_Mutation	rs778590962	A669T	0.2
HNSC	chr17	75662524	Silent	rs747334511	L242L	0.36
KICH	chr17	75630266	Missense_Mutation	rs199975622	R577Q	0.39
KIRC	chr17	75661631	Silent	NA	G283G	0.26
KIRC	chr17	75667175	5'UTR	novel		0.43
KIRC	chr17	75658447	Missense_Mutation	NA	W334G	0.21
KIRC	chr17	75662669	Frame_Shift_Ins	novel	*T194Ifs35**	0.07
KIRC	chr17	75662670	In_Frame_Ins	novel	A193_T194insF	0.07
KIRC	chr17	75628706	Missense_Mutation	NA	D849V	0.35
KIRP	chr17	75658420	Missense_Mutation	novel	Y343H	0.33
LGG	chr17	75631518	Silent	novel	P460P	0.38
LGG	chr17	75651071	Intron	novel		0.46
LGG	chr17	75662506	Missense_Mutation	novel	K248N	0.08
LIHC	chr17	75629450	Missense_Mutation	novel	G658V	0.28
LUAD	chr17	75661648	Missense_Mutation	NA	E278Q	0.08
LUAD	chr17	75662884	Silent	novel	Q122Q	0.18
LUAD	chr17	75662618	Missense_Mutation	novel	K211T	0.04
LUAD	chr17	75666459	Silent	NA	L33L	0.29
LUAD	chr17	75630994	Missense_Mutation	NA	I522K	0.19
LUAD	chr17	75651147	Intron	novel		0.05
LUAD	chr17	75631225	Silent	NA	S491S	0.22
LUAD	chr17	75631552	Missense_Mutation	rs372347188	R449H	0.11
LUAD	chr17	75650999	Intron	novel		0.28
LUAD	chr17	75631595	Missense_Mutation	novel	Q435K	0.14
LUAD	chr17	75651124	Intron	novel		0.24
LUAD	chr17	75661048	Missense_Mutation	novel	R298I	0.19
LUAD	chr17	75662922	Nonsense_Mutation	novel	K110*	0.17
LUSC	chr17	75662515	Missense_Mutation	NA	F245L	0.16
LUSC	chr17	75628408	Missense_Mutation	rs372355133	R872H	0.13
LUSC	chr17	75650743	Intron	NA		0.17
LUSC	chr17	75627194	3'UTR	novel		0.71
LUSC	chr17	75651018	Intron	novel		0.08
LUSC	chr17	75661640	Silent	novel	S280S	0.59
LUSC	chr17	75627327	3'UTR	novel		0.19
LUSC	chr17	75651020	Intron	novel		0.22
LUSC	chr17	75662594	Missense_Mutation	novel	P219R	0.16
OV	chr17	75628352	Missense_Mutation	rs758403193	E891K	0.09
OV	chr17	75662697	Missense_Mutation	novel	H185D	0.07
OV	chr17	75666538	Frame_Shift_Ins	novel	*T7Sfs12**	0.05
OV	chr17	75651109	Intron	novel		0.18
OV	chr17	75650946	Intron	novel		0.38
PAAD	chr17	75628722	Missense_Mutation	novel	P844S	0.03
PRAD	chr17	75631191	Missense_Mutation	NA	E503Q	0.37
PRAD	chr17	75631665	Silent	NA	C411C	0.07
READ	chr17	75628296	Silent	rs761415779	G909G	0.19
READ	chr17	75662673	Missense_Mutation	NA	A193T	0.23
READ	chr17	75658386	Missense_Mutation	NA	G354V	0.24
READ	chr17	75651173	Intron	novel		0.29
READ	chr17	75629334	Missense_Mutation	NA	P697S	0.26
SARC	chr17	75624589	3'Flank	rs547975613		0.25
SARC	chr17	75628751	Missense_Mutation	novel	P834H	0.12
SKCM	chr17	75629268	Missense_Mutation	NA	G719S	0.29
SKCM	chr17	75665127	Missense_Mutation	NA	S59F	0.31	ResIII
SKCM	chr17	75630620	Missense_Mutation	NA	E573K	0.23
SKCM	chr17	75651262	Missense_Mutation	novel	K385E	0.24
SKCM	chr17	75627259	3'UTR	novel		0.18
SKCM	chr17	75629448	Missense_Mutation	novel	F659I	0.21
SKCM	chr17	75629449	Silent	novel	G658G	0.19
SKCM	chr17	75627460	Missense_Mutation	rs761941890	E980K	0.1
SKCM	chr17	75662846	Missense_Mutation	novel	S135L	0.26
SKCM	chr17	75662557	Silent	NA	F231F	0.3
SKCM	chr17	75628956	Missense_Mutation	novel	E823K	0.39
SKCM	chr17	75629446	Silent	rs534760049	F659F	0.13
SKCM	chr17	75662835	Nonsense_Mutation	NA	Q139*	0.13
SKCM	chr17	75629275	Silent	NA	V716V	0.26
SKCM	chr17	75662808	Missense_Mutation	rs780333281	R148C	0.31
SKCM	chr17	75629240	Missense_Mutation	NA	P728L	0.13
SKCM	chr17	75628846	Intron	novel		0.39
SKCM	chr17	75662975	Missense_Mutation	NA	T92I	0.44	ResIII
SKCM	chr17	75629464	Silent	NA	K653K	0.44
SKCM	chr17	75661039	Missense_Mutation	NA	V301G	0.07
SKCM	chr17	75631010	Missense_Mutation	NA	G517S	0.28
SKCM	chr17	75662742	Missense_Mutation	NA	R170C	0.16
SKCM	chr17	75662605	Silent	NA	I215I	0.34
SKCM	chr17	75629343	Missense_Mutation	NA	P694S	0.25
SKCM	chr17	75629252	Missense_Mutation	novel	G724E	0.58
STAD	chr17	75631157	Missense_Mutation	novel	L514P	0.24
STAD	chr17	75629428	Silent	rs768340637	P665P	0.14
STAD	chr17	75629088	Missense_Mutation	rs556638061	A779T	0.28
STAD	chr17	75650560	Intron	novel		0.43
STAD	chr17	75629077	Frame_Shift_Del	novel	*P782Rfs10**	0.11
STAD	chr17	75662890	Frame_Shift_Ins	novel	*P121Afs38**	0.2
STAD	chr17	75629248	Frame_Shift_Del	novel	*S727Pfs27**	0.46
STAD	chr17	75631225	Silent	NA	S491S	0.4
STAD	chr17	75662586	Missense_Mutation	rs765614838	R222W	0.06
STAD	chr17	75658316	Missense_Mutation	novel	K377N	0.09
STAD	chr17	75658422	Missense_Mutation	novel	G342V	0.06
STAD	chr17	75631638	Silent	rs192546084	F420F	0.14
STAD	chr17	75631606	Missense_Mutation	NA	C431Y	0.24
STAD	chr17	75629042	Missense_Mutation	NA	V794A	0.32
STAD	chr17	75627520	Missense_Mutation	novel	K960E	0.06
STAD	chr17	75630628	Missense_Mutation	rs760175418	T570I	0.2
STAD	chr17	75630627	Silent	rs376083388	T570T	0.15
STAD	chr17	75650665	Intron	novel		0.09
UCEC	chr17	75631155	Missense_Mutation	rs375117491	R515C	0.24
UCEC	chr17	75658369	Missense_Mutation	rs769730810	R360C	0.21
UCEC	chr17	75629314	Missense_Mutation	NA	E703D	0.19
UCEC	chr17	75662863	Silent	NA	T129T	0.1
UCEC	chr17	75666508	Missense_Mutation	rs767761106	R17Q	0.3	ResIII
UCEC	chr17	75625853	3'Flank	novel		0.4
UCEC	chr17	75650787	Intron	novel		0.62
UCEC	chr17	75658453	Missense_Mutation	rs201204572	A332T	0.39
UCEC	chr17	75624898	3'Flank	novel		0.32
UCEC	chr17	75625126	3'Flank	novel		0.37
UCEC	chr17	75629115	Nonsense_Mutation	rs532732579	R770*	0.46
UCEC	chr17	75650854	Intron	novel		0.67
UCEC	chr17	75630244	Silent	NA	E584E	0.07
UCEC	chr17	75630813	Missense_Mutation	NA	A537V	0.12
UCEC	chr17	75651096	Intron	rs534785198		0.17
UCEC	chr17	75660974	Missense_Mutation	NA	V323M	0.24
UCEC	chr17	75627479	Silent	NA	G973G	0.27
UCEC	chr17	75665093	Missense_Mutation	novel	K70N	0.21	ResIII
UCEC	chr17	75631004	Missense_Mutation	NA	D519Y	0.39
UCEC	chr17	75666612	Intron	novel		0.33
UCEC	chr17	75625807	3'Flank	novel		0.32
UCEC	chr17	75628686	Missense_Mutation	novel	P856S	0.28
UCEC	chr17	75630631	Missense_Mutation	rs368304075	R569H	0.46
UCEC	chr17	75622060	3'Flank	novel		0.2
UCEC	chr17	75662594	Missense_Mutation	novel	P219L	0.46
UCEC	chr17	75630626	Missense_Mutation	rs771692549	A571T	0.35
UCEC	chr17	75631494	Silent	novel	P468P	0.36
UCEC	chr17	75650448	Intron	novel		0.4
UCEC	chr17	75662620	Missense_Mutation	novel	K210N	0.22
UCEC	chr17	75666608	Intron	novel		0.22
UCEC	chr17	75662732	Missense_Mutation	novel	Y173C	0.09
UCEC	chr17	75666429	Missense_Mutation	novel	K43N	0.56	ResIII
UCEC	chr17	75624040	3'Flank	novel		0.2
UCEC	chr17	75624373	3'Flank	novel		0.2
UCEC	chr17	75625870	3'Flank	rs564610579		0.55
UCEC	chr17	75631155	Missense_Mutation	rs375117491	R515C	0.19
UCEC	chr17	75624579	3'Flank	novel		0.6
UCEC	chr17	75662945	Missense_Mutation	NA	S102L	0.38	ResIII
UCEC	chr17	75661700	Silent	novel	G260G	0.24
UCEC	chr17	75625839	3'Flank	rs758572554		0.54
UCEC	chr17	75662585	Missense_Mutation	rs762104670	R222Q	0.33
UCEC	chr17	75662727	Missense_Mutation	novel	R175C	0.18
UCEC	chr17	75666509	Silent	novel	R17R	0.21
UCEC	chr17	75623963	3'Flank	rs760833606		0.45
UCEC	chr17	75662563	Silent	NA	V229V	0.61
UCEC	chr17	75629248	Frame_Shift_Del	novel	*S727Pfs27**	0.38
UCEC	chr17	75650543	Intron	novel		0.17
UCEC	chr17	75624240	3'Flank	novel		0.38
UCEC	chr17	75661032	Silent	rs768907988	N303N	0.34
UCEC	chr17	75627462	Missense_Mutation	rs201830334	S979N	0.07
UCEC	chr17	75658352	Silent	rs147394651	R365R	0.45
UCEC	chr17	75624880	3'Flank	rs575992558		0.29
UCEC	chr17	75628293	Silent	rs768951052	V910V	0.22
UCEC	chr17	75624221	3'Flank	novel		0.46
UCEC	chr17	75625174	3'Flank	novel		0.12
UCEC	chr17	75629203	Silent	novel	S740S	0.27
UCEC	chr17	75628946	Missense_Mutation	novel	R826M	0.29
UCEC	chr17	75629017	Missense_Mutation	NA	E802D	0.27
UCEC	chr17	75651029	Intron	novel		0.25
UCEC	chr17	75662727	Missense_Mutation	novel	R175C	0.2
UCEC	chr17	75662919	Nonsense_Mutation	novel	E111*	0.19
UCEC	chr17	75666619	Intron	novel		0.23
UCEC	chr17	75625965	3'Flank	novel		0.25
UCEC	chr17	75627472	Missense_Mutation	rs752348322	R976W	0.46
UCEC	chr17	75651095	Intron	novel		0.5
UCEC	chr17	75630628	Missense_Mutation	rs760175418	T570I	0.33
UCEC	chr17	75631483	Missense_Mutation	novel	E472A	0.16
UCEC	chr17	75622060	3'Flank	novel		0.44
UCEC	chr17	75625122	3'Flank	novel		0.24
UCEC	chr17	75631616	Missense_Mutation	rs201206387	A428T	0.42
UCEC	chr17	75665061	Missense_Mutation	novel	A81V	0.34	ResIII
UCS	chr17	75665120	Silent	novel	C61C	0.48
UVM	chr17	75627466	Missense_Mutation	rs766805103	E978K	0.24

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3946	0.00012456
CESC	AMP	0.2068	2.0209e-05
GBM	AMP	0.0919	0.0035457
KIRP	AMP	0.6701	0.14801
LGG	AMP	0.0702	1.52e-05
LUSC	AMP	0.3573	0.001059
SARC	AMP	0.2412	0.032181
SKCM	AMP	0.2943	7.0388e-08
THCA	DEL	0.002	0.221
UCEC	AMP	0.154	2.3259e-11
UCS	AMP	0.4821	0.0006294
UVM	AMP	0.1625	0.054583

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00011	Kaplan-Meier Survival Analysis
MESO	0.0077	Kaplan-Meier Survival Analysis
ACC	0.019	Kaplan-Meier Survival Analysis
PRAD	0.026	Kaplan-Meier Survival Analysis
COAD	0.02	Kaplan-Meier Survival Analysis
PAAD	0.0001	Kaplan-Meier Survival Analysis
BLCA	0.045	Kaplan-Meier Survival Analysis
CESC	0.017	Kaplan-Meier Survival Analysis
READ	0.01	Kaplan-Meier Survival Analysis
UCEC	0.00062	Kaplan-Meier Survival Analysis
LIHC	0.0058	Kaplan-Meier Survival Analysis
LGG	0.027	Kaplan-Meier Survival Analysis
UVM	0.0062	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000108469 (Gene tree)
Gene ID: 9400
Gene Symbol: RECQL5
Alias: RecQ5|FLJ90603
Full Name: RecQ like helicase 5
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 40,347 bases
Position: chr17:75,626,845-75,667,191
Accession: 9950
RBP type: canonical RBP
Summary: The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000414933	ResIII	PF04851.15	4.3e-05	1	1
ENSP00000341983	ResIII	PF04851.15	4.8e-05	1	1
ENSP00000462248	ResIII	PF04851.15	4.8e-05	1	1
ENSP00000463099	ResIII	PF04851.15	6.1e-05	1	1
ENSP00000317636	ResIII	PF04851.15	0.0002	1	1
ENSP00000414933	DEAD	PF00270.29	2.9e-21	1	1
ENSP00000341983	DEAD	PF00270.29	3.3e-21	1	1
ENSP00000462248	DEAD	PF00270.29	3.3e-21	1	1
ENSP00000463099	DEAD	PF00270.29	4.3e-21	1	1
ENSP00000317636	DEAD	PF00270.29	1.8e-20	1	1
ENSP00000394820	DEAD	PF00270.29	4e-10	1	1
ENSP00000462547	DEAD	PF00270.29	1e-06	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
24253305	Molecular recognition by the KIX domain and its role in gene regulation.	Nucleic Acids Res	2014 Feb	Thakur JK	doi: 10.1093/nar/gkt1147

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000578201	RECQL5-206	1972	-	ENSP00000463099	480 (aa)	-	J3KTQ2
ENST00000317905	RECQL5-201	3704	XM_005257818	ENSP00000317636	991 (aa)	XP_005257875	O94762
ENST00000578865	RECQL5-207	1176	-	-	- (aa)	-	-
ENST00000579739	RECQL5-210	630	-	-	- (aa)	-	-
ENST00000583673	RECQL5-217	547	-	-	- (aa)	-	-
ENST00000420326	RECQL5-203	3710	-	ENSP00000414933	410 (aa)	-	O94762
ENST00000584999	RECQL5-218	1922	-	ENSP00000462248	435 (aa)	-	O94762
ENST00000585205	RECQL5-219	519	-	-	- (aa)	-	-
ENST00000340830	RECQL5-202	1749	-	ENSP00000341983	435 (aa)	-	O94762
ENST00000443199	RECQL5-205	3089	-	-	- (aa)	-	-
ENST00000423245	RECQL5-204	3576	-	ENSP00000394820	964 (aa)	-	O94762
ENST00000581825	RECQL5-213	793	-	ENSP00000462678	206 (aa)	-	J3KSV9
ENST00000581827	RECQL5-214	543	-	-	- (aa)	-	-
ENST00000582548	RECQL5-216	709	-	ENSP00000462291	236 (aa)	-	J3KS37
ENST00000582464	RECQL5-215	656	-	ENSP00000462077	118 (aa)	-	J3KRM6
ENST00000579265	RECQL5-208	333	-	-	- (aa)	-	-
ENST00000579274	RECQL5-209	182	-	-	- (aa)	-	-
ENST00000580707	RECQL5-212	948	-	ENSP00000463701	190 (aa)	-	J3QLU0
ENST00000580078	RECQL5-211	816	-	ENSP00000462547	198 (aa)	-	J3KSL7

Gene Model

Click here to download ENSG00000108469's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000108469's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000108469	RECQL5	96	64.141	ENSAPOG00000018549	recql5	99	47.116	Acanthochromis_polyacanthus
ENSG00000108469	RECQL5	100	92.457	ENSAMEG00000009566	RECQL5	100	82.460	Ailuropoda_melanoleuca
ENSG00000108469	RECQL5	97	63.819	ENSACIG00000006402	recql5	99	43.872	Amphilophus_citrinellus
ENSG00000108469	RECQL5	96	63.636	ENSAOCG00000000898	recql5	99	46.505	Amphiprion_ocellaris
ENSG00000108469	RECQL5	96	63.889	ENSAPEG00000014670	recql5	99	46.790	Amphiprion_percula
ENSG00000108469	RECQL5	96	64.646	ENSATEG00000004392	recql5	99	47.697	Anabas_testudineus
ENSG00000108469	RECQL5	99	78.431	ENSAPLG00000011106	RECQL5	99	59.663	Anas_platyrhynchos
ENSG00000108469	RECQL5	96	77.582	ENSACAG00000006875	RECQL5	97	54.906	Anolis_carolinensis
ENSG00000108469	RECQL5	100	97.561	ENSANAG00000026587	RECQL5	100	95.632	Aotus_nancymaae
ENSG00000108469	RECQL5	96	63.889	ENSACLG00000008356	recql5	97	63.889	Astatotilapia_calliptera
ENSG00000108469	RECQL5	96	65.657	ENSAMXG00000009293	recql5	97	47.969	Astyanax_mexicanus
ENSG00000108469	RECQL5	99	91.912	ENSBTAG00000011715	RECQL5	99	80.544	Bos_taurus
ENSG00000108469	RECQL5	97	42.857	WBGene00004322	rcq-5	78	37.733	Caenorhabditis_elegans
ENSG00000108469	RECQL5	100	96.341	ENSCJAG00000014183	RECQL5	99	94.457	Callithrix_jacchus
ENSG00000108469	RECQL5	100	93.187	ENSCAFG00000004860	RECQL5	100	83.199	Canis_familiaris
ENSG00000108469	RECQL5	100	93.187	ENSCAFG00020000819	RECQL5	100	83.099	Canis_lupus_dingo
ENSG00000108469	RECQL5	100	91.707	ENSCHIG00000009742	RECQL5	100	79.397	Capra_hircus
ENSG00000108469	RECQL5	100	93.171	ENSTSYG00000031875	RECQL5	99	91.475	Carlito_syrichta
ENSG00000108469	RECQL5	100	90.244	ENSCPOG00000012645	RECQL5	100	86.647	Cavia_porcellus
ENSG00000108469	RECQL5	100	97.317	ENSCCAG00000031546	RECQL5	100	95.632	Cebus_capucinus
ENSG00000108469	RECQL5	100	98.293	ENSCATG00000029763	RECQL5	100	97.471	Cercocebus_atys
ENSG00000108469	RECQL5	100	91.951	ENSCLAG00000006680	RECQL5	100	81.149	Chinchilla_lanigera
ENSG00000108469	RECQL5	100	98.537	ENSCSAG00000004842	RECQL5	100	96.670	Chlorocebus_sabaeus
ENSG00000108469	RECQL5	100	90.976	ENSCHOG00000000629	RECQL5	76	90.976	Choloepus_hoffmanni
ENSG00000108469	RECQL5	97	81.658	ENSCPBG00000028060	RECQL5	99	59.170	Chrysemys_picta_bellii
ENSG00000108469	RECQL5	96	54.386	ENSCSAVG00000004094	-	99	54.167	Ciona_savignyi
ENSG00000108469	RECQL5	100	98.293	ENSCANG00000038821	RECQL5	100	97.011	Colobus_angolensis_palliatus
ENSG00000108469	RECQL5	100	83.698	ENSCGRG00001011255	Recql5	100	73.992	Cricetulus_griseus_chok1gshd
ENSG00000108469	RECQL5	96	64.646	ENSCSEG00000017761	recql5	99	46.261	Cynoglossus_semilaevis
ENSG00000108469	RECQL5	96	63.131	ENSCVAG00000014937	recql5	98	46.881	Cyprinodon_variegatus
ENSG00000108469	RECQL5	96	63.384	ENSDARG00000059556	recql5	92	62.821	Danio_rerio
ENSG00000108469	RECQL5	93	92.969	ENSDNOG00000012832	-	100	92.969	Dasypus_novemcinctus
ENSG00000108469	RECQL5	100	90.488	ENSDORG00000004086	Recql5	100	78.024	Dipodomys_ordii
ENSG00000108469	RECQL5	96	51.372	FBgn0027375	RecQ5	95	49.887	Drosophila_melanogaster
ENSG00000108469	RECQL5	100	80.779	ENSETEG00000010420	-	81	80.779	Echinops_telfairi
ENSG00000108469	RECQL5	96	60.050	ENSEBUG00000011061	recql5	80	60.050	Eptatretus_burgeri
ENSG00000108469	RECQL5	99	93.137	ENSEASG00005000704	RECQL5	99	85.945	Equus_asinus_asinus
ENSG00000108469	RECQL5	99	93.382	ENSECAG00000007563	RECQL5	99	86.047	Equus_caballus
ENSG00000108469	RECQL5	96	64.750	ENSELUG00000017281	recql5	97	43.928	Esox_lucius
ENSG00000108469	RECQL5	100	91.971	ENSFCAG00000005751	RECQL5	100	82.460	Felis_catus
ENSG00000108469	RECQL5	97	81.000	ENSFALG00000001087	RECQL5	94	58.624	Ficedula_albicollis
ENSG00000108469	RECQL5	100	90.732	ENSFDAG00000012561	RECQL5	100	79.919	Fukomys_damarensis
ENSG00000108469	RECQL5	96	63.384	ENSFHEG00000019476	recql5	99	45.906	Fundulus_heteroclitus
ENSG00000108469	RECQL5	96	63.198	ENSGMOG00000009835	recql5	59	66.216	Gadus_morhua
ENSG00000108469	RECQL5	97	80.402	ENSGALG00000002424	RECQL5	98	58.317	Gallus_gallus
ENSG00000108469	RECQL5	96	64.394	ENSGAFG00000005911	recql5	99	46.123	Gambusia_affinis
ENSG00000108469	RECQL5	95	64.796	ENSGACG00000013287	recql5	99	44.068	Gasterosteus_aculeatus
ENSG00000108469	RECQL5	97	81.910	ENSGAGG00000006847	RECQL5	99	59.788	Gopherus_agassizii
ENSG00000108469	RECQL5	100	100.000	ENSGGOG00000009481	RECQL5	100	99.770	Gorilla_gorilla
ENSG00000108469	RECQL5	96	63.889	ENSHBUG00000020297	recql5	96	61.099	Haplochromis_burtoni
ENSG00000108469	RECQL5	100	91.707	ENSHGLG00000013222	RECQL5	100	82.442	Heterocephalus_glaber_female
ENSG00000108469	RECQL5	100	91.707	ENSHGLG00100004847	RECQL5	100	82.442	Heterocephalus_glaber_male
ENSG00000108469	RECQL5	96	60.914	ENSHCOG00000014953	recql5	97	45.445	Hippocampus_comes
ENSG00000108469	RECQL5	96	63.980	ENSIPUG00000009326	recql5	98	46.957	Ictalurus_punctatus
ENSG00000108469	RECQL5	100	90.268	ENSSTOG00000012970	RECQL5	99	81.937	Ictidomys_tridecemlineatus
ENSG00000108469	RECQL5	100	89.538	ENSJJAG00000012288	Recql5	99	78.305	Jaculus_jaculus
ENSG00000108469	RECQL5	95	64.796	ENSKMAG00000008993	recql5	99	47.554	Kryptolebias_marmoratus
ENSG00000108469	RECQL5	96	61.071	ENSLBEG00000019135	recql5	98	60.142	Labrus_bergylta
ENSG00000108469	RECQL5	94	63.660	ENSLBEG00000019206	recql5	99	45.427	Labrus_bergylta
ENSG00000108469	RECQL5	97	73.116	ENSLACG00000012080	RECQL5	97	52.626	Latimeria_chalumnae
ENSG00000108469	RECQL5	98	66.915	ENSLOCG00000011489	recql5	98	51.670	Lepisosteus_oculatus
ENSG00000108469	RECQL5	100	91.220	ENSLAFG00000008491	RECQL5	100	79.326	Loxodonta_africana
ENSG00000108469	RECQL5	100	98.049	ENSMFAG00000044550	RECQL5	100	97.241	Macaca_fascicularis
ENSG00000108469	RECQL5	100	97.805	ENSMMUG00000021635	RECQL5	100	95.964	Macaca_mulatta
ENSG00000108469	RECQL5	100	98.049	ENSMNEG00000040154	RECQL5	100	97.011	Macaca_nemestrina
ENSG00000108469	RECQL5	100	98.537	ENSMLEG00000033070	RECQL5	100	97.701	Mandrillus_leucophaeus
ENSG00000108469	RECQL5	96	63.959	ENSMAMG00000002948	recql5	99	46.550	Mastacembelus_armatus
ENSG00000108469	RECQL5	96	63.889	ENSMZEG00005008718	recql5	99	46.648	Maylandia_zebra
ENSG00000108469	RECQL5	97	80.905	ENSMGAG00000004920	RECQL5	98	58.043	Meleagris_gallopavo
ENSG00000108469	RECQL5	99	85.208	ENSMAUG00000017594	Recql5	100	73.347	Mesocricetus_auratus
ENSG00000108469	RECQL5	99	92.099	ENSMICG00000007529	RECQL5	99	86.626	Microcebus_murinus
ENSG00000108469	RECQL5	100	85.888	ENSMOCG00000019642	Recql5	100	74.899	Microtus_ochrogaster
ENSG00000108469	RECQL5	95	65.051	ENSMMOG00000012466	recql5	98	47.591	Mola_mola
ENSG00000108469	RECQL5	99	84.483	ENSMODG00000007532	RECQL5	99	64.706	Monodelphis_domestica
ENSG00000108469	RECQL5	89	63.934	ENSMALG00000019460	recql5	99	49.389	Monopterus_albus
ENSG00000108469	RECQL5	100	90.024	MGP_CAROLIEiJ_G0017420	Recql5	97	86.726	Mus_caroli
ENSG00000108469	RECQL5	100	90.511	ENSMUSG00000020752	Recql5	97	87.611	Mus_musculus
ENSG00000108469	RECQL5	100	89.781	MGP_PahariEiJ_G0018550	Recql5	97	87.168	Mus_pahari
ENSG00000108469	RECQL5	100	90.511	MGP_SPRETEiJ_G0018265	Recql5	97	87.168	Mus_spretus
ENSG00000108469	RECQL5	98	93.532	ENSMPUG00000013833	RECQL5	99	82.503	Mustela_putorius_furo
ENSG00000108469	RECQL5	100	89.952	ENSMLUG00000015374	RECQL5	98	81.000	Myotis_lucifugus
ENSG00000108469	RECQL5	100	92.195	ENSNGAG00000003784	Recql5	100	79.859	Nannospalax_galili
ENSG00000108469	RECQL5	95	61.598	ENSNBRG00000001856	recql5	99	44.401	Neolamprologus_brichardi
ENSG00000108469	RECQL5	100	99.310	ENSNLEG00000001129	RECQL5	100	99.310	Nomascus_leucogenys
ENSG00000108469	RECQL5	100	90.000	ENSOPRG00000012657	RECQL5	94	78.531	Ochotona_princeps
ENSG00000108469	RECQL5	100	63.835	ENSONIG00000019427	recql5	99	48.683	Oreochromis_niloticus
ENSG00000108469	RECQL5	97	79.198	ENSOANG00000015844	-	97	79.198	Ornithorhynchus_anatinus
ENSG00000108469	RECQL5	100	90.024	ENSOCUG00000016202	RECQL5	95	79.358	Oryctolagus_cuniculus
ENSG00000108469	RECQL5	96	63.706	ENSORLG00000012294	recql5	99	46.660	Oryzias_latipes
ENSG00000108469	RECQL5	96	63.959	ENSORLG00020012036	recql5	98	46.903	Oryzias_latipes_hni
ENSG00000108469	RECQL5	96	63.959	ENSORLG00015022707	recql5	99	46.869	Oryzias_latipes_hsok
ENSG00000108469	RECQL5	96	64.721	ENSOMEG00000019069	recql5	95	48.352	Oryzias_melastigma
ENSG00000108469	RECQL5	100	92.439	ENSOGAG00000001457	RECQL5	100	85.368	Otolemur_garnettii
ENSG00000108469	RECQL5	99	91.422	ENSOARG00000010133	RECQL5	96	78.332	Ovis_aries
ENSG00000108469	RECQL5	100	99.540	ENSPPAG00000034423	RECQL5	100	99.540	Pan_paniscus
ENSG00000108469	RECQL5	100	91.727	ENSPPRG00000004541	RECQL5	100	82.258	Panthera_pardus
ENSG00000108469	RECQL5	100	91.241	ENSPTIG00000020601	RECQL5	95	91.241	Panthera_tigris_altaica
ENSG00000108469	RECQL5	100	99.540	ENSPTRG00000009651	RECQL5	100	99.540	Pan_troglodytes
ENSG00000108469	RECQL5	100	98.293	ENSPANG00000020139	RECQL5	100	97.471	Papio_anubis
ENSG00000108469	RECQL5	97	62.633	ENSPKIG00000023225	recql5	98	47.301	Paramormyrops_kingsleyae
ENSG00000108469	RECQL5	97	80.905	ENSPSIG00000005110	-	96	80.905	Pelodiscus_sinensis
ENSG00000108469	RECQL5	96	64.394	ENSPMGG00000016582	recql5	98	43.634	Periophthalmus_magnuspinnatus
ENSG00000108469	RECQL5	100	91.727	ENSPEMG00000011938	Recql5	100	76.815	Peromyscus_maniculatus_bairdii
ENSG00000108469	RECQL5	96	65.578	ENSPMAG00000004572	recql5	100	57.869	Petromyzon_marinus
ENSG00000108469	RECQL5	99	84.521	ENSPCIG00000020398	RECQL5	99	69.310	Phascolarctos_cinereus
ENSG00000108469	RECQL5	96	63.636	ENSPFOG00000006282	recql5	99	45.366	Poecilia_formosa
ENSG00000108469	RECQL5	96	63.636	ENSPLAG00000019969	recql5	80	55.224	Poecilia_latipinna
ENSG00000108469	RECQL5	96	63.636	ENSPMEG00000024321	recql5	99	45.849	Poecilia_mexicana
ENSG00000108469	RECQL5	96	63.889	ENSPREG00000015737	recql5	83	55.821	Poecilia_reticulata
ENSG00000108469	RECQL5	100	99.268	ENSPPYG00000008632	RECQL5	100	95.751	Pongo_abelii
ENSG00000108469	RECQL5	100	90.732	ENSPCAG00000003894	RECQL5	100	72.782	Procavia_capensis
ENSG00000108469	RECQL5	100	92.195	ENSPCOG00000000050	RECQL5	100	86.794	Propithecus_coquereli
ENSG00000108469	RECQL5	100	90.976	ENSPVAG00000008452	RECQL5	100	82.560	Pteropus_vampyrus
ENSG00000108469	RECQL5	96	63.889	ENSPNYG00000017402	recql5	99	44.719	Pundamilia_nyererei
ENSG00000108469	RECQL5	95	65.561	ENSPNAG00000012993	recql5	98	48.083	Pygocentrus_nattereri
ENSG00000108469	RECQL5	100	90.754	ENSRNOG00000005107	Recql5	100	76.210	Rattus_norvegicus
ENSG00000108469	RECQL5	100	98.293	ENSRBIG00000008500	RECQL5	100	97.471	Rhinopithecus_bieti
ENSG00000108469	RECQL5	100	98.293	ENSRROG00000043301	RECQL5	100	97.471	Rhinopithecus_roxellana
ENSG00000108469	RECQL5	100	97.073	ENSSBOG00000033729	RECQL5	100	94.943	Saimiri_boliviensis_boliviensis
ENSG00000108469	RECQL5	99	82.801	ENSSHAG00000017920	RECQL5	99	65.837	Sarcophilus_harrisii
ENSG00000108469	RECQL5	96	62.879	ENSSFOG00015003752	recql5	99	46.169	Scleropages_formosus
ENSG00000108469	RECQL5	95	63.776	ENSSMAG00000009346	recql5	98	46.595	Scophthalmus_maximus
ENSG00000108469	RECQL5	96	64.899	ENSSDUG00000016220	recql5	99	46.405	Seriola_dumerili
ENSG00000108469	RECQL5	96	64.899	ENSSLDG00000000987	recql5	99	46.494	Seriola_lalandi_dorsalis
ENSG00000108469	RECQL5	97	82.000	ENSSPUG00000008872	RECQL5	92	81.265	Sphenodon_punctatus
ENSG00000108469	RECQL5	96	63.384	ENSSPAG00000011094	recql5	99	46.577	Stegastes_partitus
ENSG00000108469	RECQL5	99	91.605	ENSSSCG00000023978	RECQL5	99	81.744	Sus_scrofa
ENSG00000108469	RECQL5	97	81.250	ENSTGUG00000008444	RECQL5	99	61.083	Taeniopygia_guttata
ENSG00000108469	RECQL5	96	64.122	ENSTRUG00000008246	recql5	95	42.697	Takifugu_rubripes
ENSG00000108469	RECQL5	97	65.239	ENSTNIG00000011592	recql5	99	48.491	Tetraodon_nigroviridis
ENSG00000108469	RECQL5	78	94.565	ENSTBEG00000015250	RECQL5	65	89.286	Tupaia_belangeri
ENSG00000108469	RECQL5	89	91.257	ENSTTRG00000015879	RECQL5	100	81.962	Tursiops_truncatus
ENSG00000108469	RECQL5	100	92.457	ENSUAMG00000002850	RECQL5	100	83.165	Ursus_americanus
ENSG00000108469	RECQL5	100	92.457	ENSUMAG00000009115	RECQL5	100	83.367	Ursus_maritimus
ENSG00000108469	RECQL5	100	91.971	ENSVVUG00000011515	RECQL5	100	82.495	Vulpes_vulpes
ENSG00000108469	RECQL5	99	70.762	ENSXETG00000032721	RECQL5	99	52.605	Xenopus_tropicalis
ENSG00000108469	RECQL5	96	63.636	ENSXCOG00000018067	recql5	98	46.000	Xiphophorus_couchianus
ENSG00000108469	RECQL5	96	63.384	ENSXMAG00000012133	recql5	98	46.562	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000070	mitotic sister chromatid segregation	21873635.	IBA	Process
GO:0000278	mitotic cell cycle	22013166.	IMP	Process
GO:0000724	double-strand break repair via homologous recombination	21873635.	IBA	Process
GO:0000993	RNA polymerase II complex binding	21873635.	IBA	Function
GO:0000993	RNA polymerase II complex binding	23748380.	IDA	Function
GO:0003677	DNA binding	21873635.	IBA	Function
GO:0003678	DNA helicase activity	22013166.	IDA	Function
GO:0003678	DNA helicase activity	10710432.	NAS	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	22013166.	IDA	Component
GO:0005654	nucleoplasm	10710432.	NAS	Component
GO:0005694	chromosome	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	10710432.	NAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006259	DNA metabolic process	10710432.	NAS	Process
GO:0006260	DNA replication	21873635.	IBA	Process
GO:0006260	DNA replication	22013166.	IMP	Process
GO:0006281	DNA repair	21873635.	IBA	Process
GO:0006281	DNA repair	22973052.	IMP	Process
GO:0006310	DNA recombination	21873635.	IBA	Process
GO:0009378	four-way junction helicase activity	21873635.	IBA	Function
GO:0010165	response to X-ray	21873635.	IBA	Process
GO:0016591	RNA polymerase II, holoenzyme	22231121.	IDA	Component
GO:0032508	DNA duplex unwinding	21873635.	IBA	Process
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	21873635.	IBA	Process
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	23748380.	IDA	Process
GO:0042802	identical protein binding	21873635.	IBA	Function
GO:0043140	ATP-dependent 3'-5' DNA helicase activity	21873635.	IBA	Function
GO:0045930	negative regulation of mitotic cell cycle	21873635.	IBA	Process
GO:0051301	cell division	-	IEA	Process
GO:0051304	chromosome separation	22013166.	IMP	Process
GO:0072757	cellular response to camptothecin	-	IEA	Process
GO:1990414	replication-born double-strand break repair via sister chromatid exchange	21873635.	IBA	Process
GO:2000042	negative regulation of double-strand break repair via homologous recombination	21873635.	IBA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.