EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25808865	PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy.	Cancer Res	2015 May 15	Hsieh CL	doi: 10.1158/0008-5472.CAN-14-3602
30431129	Tumor suppressor PLZF regulated by lncRNA ANRIL suppresses proliferation and epithelial mesenchymal transformation of gastric cancer cells.	Oncol Rep	2019 Feb	Wang JB	doi: 10.3892/or.2018.6866
16828757	A novel cervical cancer suppressor 3 (CCS-3) interacts with the BTB domain of PLZF and inhibits the cell growth by inducing apoptosis.	FEBS Lett	2006 Jul 24	Rho SB	-
18771349	Increased expression of the tumor suppressor PLZF is a continuous predictor of long-term survival in malignant melanoma patients.	Cancer Biother Radiopharm	2008 Aug	Brunner G	doi: 10.1089/cbr.2008.0473.
25807461	Loss of PLZF expression in prostate cancer by immunohistochemistry correlates with tumor aggressiveness and metastasis.	PLoS One	2015 Mar 25	Xiao GQ	doi: 10.1371/journal.pone.0121318
24339862	PLZF mediates the PTEN/AKT/FOXO3a signaling in suppression of prostate tumorigenesis.	PLoS One	2013 Dec 10	Cao J	doi: 10.1371/journal.pone.0077922
23280881	Identification of a novel promyelocytic leukemia zinc-finger isoform required for colorectal cancer cell growth and survival.	Int J Cancer	2013 Jul	Jones C	doi: 10.1002/ijc.28008
23804241	Hypermethylation reduces expression of tumor-suppressor PLZF and regulates proliferation and apoptosis in non-small-cell lung cancers.	FASEB J	2013 Oct	Wang X	doi: 10.1096/fj.13-229070
16637071	PLZF regulates Pbx1 transcription and Pbx1-HoxC8 complex leads to androgen-independent prostate cancer proliferation.	Prostate	2006 Jul 1	Kikugawa T	-
20945532	The Promyelocytic Leukemia Zinc Finger (PLZF) gene is a novel transcriptional target of the CCAAT-Displacement-protein (CUX1) repressor.	FEBS J	2010 Oct	Frechette I	-
26297253	Down-regulation of cytoplasmic PLZF correlates with high tumor grade and tumor aggression in non-small cell lung carcinoma.	Hum Pathol	2015 Nov	Xiao GQ	doi: 10.1016/j.humpath.2015.06.021

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr11	114064437	Silent	novel	F379F	0.23
BLCA	chr11	114063753	Silent	novel	R151R	0.26
BLCA	chr11	114063489	Silent	NA	F63F	0.86
BLCA	chr11	114063378	Missense_Mutation	novel	Q26H	0.17
BLCA	chr11	114063598	Missense_Mutation	novel	D100H	0.35
BLCA	chr11	114063688	Missense_Mutation	rs755612134	D130N	0.6
BRCA	chr11	114064309	Missense_Mutation	NA	L337V	0.52
BRCA	chr11	114064497	Silent	NA	S399S	0.42
BRCA	chr11	114250590	3'UTR	novel		0.29
BRCA	chr11	114063572	Missense_Mutation	NA	T91M	0.28
BRCA	chr11	114064001	Missense_Mutation	novel	R234L	0.19
BRCA	chr11	114187106	Intron	novel		0.2
BRCA	chr11	114064534	Missense_Mutation	rs779712380	E412K	0.7
CESC	chr11	114064117	Missense_Mutation	NA	E273K	0.46
CESC	chr11	114064065	Missense_Mutation	novel	D255E	0.8
CESC	chr11	114063714	Silent	rs147951342	A138A	0.16
CESC	chr11	114064305	Silent	rs113757018	S335S	0.69
CESC	chr11	114156405	Missense_Mutation	rs747010083	R446Q	0.34
CESC	chr11	114064295	Missense_Mutation	NA	G332V	0.43
CESC	chr11	114242281	Missense_Mutation	NA	C523S	0.73	zf-C2H2
CESC	chr11	114064201	Missense_Mutation	novel	E301K	0.19
CHOL	chr11	114250522	Silent	novel	I663I	0.59
COAD	chr11	114064148	Missense_Mutation	NA	P283L	0.51
COAD	chr11	114250637	3'UTR	novel		0.33
COAD	chr11	114242197	Frame_Shift_Ins	NA	*G496Wfs27**	0.28
COAD	chr11	114247301	Silent	NA	C576C	0.32
COAD	chr11	114250587	3'UTR	novel		0.25
COAD	chr11	114064400	Missense_Mutation	NA	D367A	0.11
COAD	chr11	114156404	Missense_Mutation	NA	R446W	0.12
COAD	chr11	114064381	Missense_Mutation	rs750494052	A361S	0.16
COAD	chr11	114187052	Intron	NA		0.4
COAD	chr11	114064347	Silent	rs200705288	P349P	0.53
COAD	chr11	114250349	Missense_Mutation	novel	L606V	0.08
COAD	chr11	114064278	Silent	rs760505512	P326P	0.2
COAD	chr11	114156368	Missense_Mutation	novel	C434S	0.06
COAD	chr11	114063477	Silent	NA	F59F	0.3
COAD	chr11	114063572	Missense_Mutation	NA	T91M	0.35
COAD	chr11	114187120	Intron	novel		0.5
COAD	chr11	114186952	Missense_Mutation	NA	A456V	0.4
COAD	chr11	114186983	Silent	rs116547293	C466C	0.36
COAD	chr11	114247223	Missense_Mutation	NA	F550L	0.3
COAD	chr11	114156365	Missense_Mutation	rs538741723	G433R	0.38
COAD	chr11	114247346	Silent	rs778496413	T591T	0.5
COAD	chr11	114187099	Intron	NA		0.34
COAD	chr11	114250403	Missense_Mutation	NA	H624Y	0.32
COAD	chr11	114250531	Silent	NA	T666T	0.23
COAD	chr11	114063646	Missense_Mutation	NA	E116K	0.15
COAD	chr11	114187021	In_Frame_Ins	novel	H479delinsQLC	0.04
COAD	chr11	114063312	Frame_Shift_Del	NA	*M6Wfs3**	0.47
COAD	chr11	114063557	Missense_Mutation	NA	Y86C	0.31
COAD	chr11	114242205	Missense_Mutation	NA	R498C	0.33
DLBC	chr11	114156364	Silent	rs148436647	Y432Y	0.19
ESCA	chr11	114063246	5'UTR	novel		0.5
ESCA	chr11	114242252	Silent	novel	A513A	0.26
ESCA	chr11	114247318	Missense_Mutation	novel	K582R	0.11
ESCA	chr11	114156371	Missense_Mutation	novel	E435K	0.06
GBM	chr11	114156434	Frame_Shift_Del	novel		0.3
GBM	chr11	114187061	Intron	novel		0.08
GBM	chr11	114063772	Missense_Mutation	novel	I158L	0.13
GBM	chr11	114156374	Frame_Shift_Del	novel	*L436Sfs12**	0.71
GBM	chr11	114250560	3'UTR	novel		0.33
GBM	chr11	114063494	Missense_Mutation	novel	R65H	0.47
GBM	chr11	114063614	Frame_Shift_Del	novel	*A105Gfs15**	0.15
HNSC	chr11	114156386	Silent	novel	R440R	0.25
HNSC	chr11	114250480	Missense_Mutation	NA	M649I	0.11
HNSC	chr11	114247256	Silent	novel	L561L	0.5
HNSC	chr11	114064184	Missense_Mutation	novel	L295Q	0.27
HNSC	chr11	114064549	Missense_Mutation	NA	E417K	0.71
HNSC	chr11	114250340	Missense_Mutation	novel	E603Q	0.48
HNSC	chr11	114064143	Silent	novel	G281G	0.26
HNSC	chr11	114063939	Silent	novel	L213L	0.31
HNSC	chr11	114250366	Silent	novel	S611S	0.25
HNSC	chr11	114156416	Missense_Mutation	rs776974563	H450Y	0.14
HNSC	chr11	114063633	Silent	rs200027612	I111I	0.7
KICH	chr11	114063573	Silent	novel	T91T	0.08
KIRC	chr11	114187048	Intron	novel		0.18
KIRC	chr11	114063698	Missense_Mutation	rs370480903	T133M	0.35
KIRC	chr11	114063791	Frame_Shift_Del	novel	*E164Gfs70**	0.15
LAML	chr11	114187130	Intron	novel		0.58
LAML	chr11	114250496	Missense_Mutation	rs755884048	E655K	0.2
LGG	chr11	114242259	Missense_Mutation	NA	R516C	0.33
LIHC	chr11	114242285	Silent	NA	N524N	0.39
LIHC	chr11	114063671	Missense_Mutation	novel	T124N	0.18
LUAD	chr11	114064010	Missense_Mutation	NA	G237V	0.14
LUAD	chr11	114250396	Silent	novel	L621L	0.12
LUAD	chr11	114063550	Missense_Mutation	NA	L84V	0.38
LUAD	chr11	114063657	Silent	novel	L119L	0.73
LUAD	chr11	114063727	Nonsense_Mutation	novel	E143*	0.38
LUAD	chr11	114064469	Missense_Mutation	novel	E390V	0.12
LUAD	chr11	114242222	Missense_Mutation	novel	S503R	0.28
LUAD	chr11	114064463	Frame_Shift_Ins	novel	*E390Gfs26**	0.23
LUAD	chr11	114064308	Silent	NA	V336V	0.49
LUAD	chr11	114250589	3'UTR	novel		0.27
LUAD	chr11	114064032	Missense_Mutation	novel	E244D	0.57
LUAD	chr11	114242326	Missense_Mutation	NA	R538L	0.26	zf-C2H2
LUAD	chr11	114242287	Missense_Mutation	novel	R525P	0.13	zf-C2H2
LUAD	chr11	114063897	Silent	NA	T199T	0.28
LUSC	chr11	114242290	Missense_Mutation	NA	T526N	0.29	zf-C2H2
LUSC	chr11	114250543	Silent	NA	L670L	0.41
LUSC	chr11	114250416	Missense_Mutation	rs767860341	S628L	0.16
LUSC	chr11	114064278	Silent	novel	P326P	0.24
LUSC	chr11	114242253	Missense_Mutation	novel	G514C	0.36
LUSC	chr11	114242199	Frame_Shift_Del	novel	*K497Sfs121**	0.59
LUSC	chr11	114063496	Missense_Mutation	NA	N66D	0.27
LUSC	chr11	114064549	Missense_Mutation	NA	E417K	0.17
LUSC	chr11	114156335	Splice_Site	novel	X423_splice	0.4
LUSC	chr11	114063218	5'UTR	novel		0.24
LUSC	chr11	114064141	Missense_Mutation	novel	G281R	0.29
LUSC	chr11	114063361	Missense_Mutation	novel	L21M	0.17
LUSC	chr11	114063369	Missense_Mutation	novel	K23N	0.45
LUSC	chr11	114063992	Missense_Mutation	novel	G231A	0.25
LUSC	chr11	114063502	Missense_Mutation	rs779616803	Q68E	0.29
LUSC	chr11	114063869	Missense_Mutation	NA	S190L	0.05
OV	chr11	114247220	Silent	novel	E549E	0.03
OV	chr11	114063495	Silent	NA	R65R	0.39
OV	chr11	114064490	Nonsense_Mutation	novel	S397*	0.23
OV	chr11	114063519	Silent	novel	D73D	0.36
OV	chr11	114064110	Missense_Mutation	NA	D270E	0.48
OV	chr11	114064283	Missense_Mutation	novel	E328V	0.1
OV	chr11	114063948	Frame_Shift_Del	novel	*T217Lfs25**	0.4
OV	chr11	114064160	Missense_Mutation	novel	S287N	0.33
OV	chr11	114250477	Frame_Shift_Del	novel	*H648Qfs2**	0.09
OV	chr11	114064092	Frame_Shift_Ins	novel	*S265Ffs9**	0.16
OV	chr11	114064161	Missense_Mutation	novel	S287R	0.45
PAAD	chr11	114063851	Missense_Mutation	novel	S184N	0.2
PRAD	chr11	114242223	Missense_Mutation	novel	A504T	0.28
PRAD	chr11	114242317	Missense_Mutation	NA	R535H	0.44	zf-C2H2
PRAD	chr11	114063251	5'UTR	rs371858413		0.13
PRAD	chr11	114247317	Missense_Mutation	novel	K582E	0.15
READ	chr11	114242205	Missense_Mutation	NA	R498C	0.35
READ	chr11	114063572	Missense_Mutation	NA	T91M	0.38
READ	chr11	114064153	Nonsense_Mutation	NA	R285*	0.29
READ	chr11	114186997	Missense_Mutation	rs761753131	S471L	0.28
READ	chr11	114242234	Silent	rs753894958	Q507Q	0.53
SARC	chr11	114063527	Missense_Mutation	novel	S76L	0.29
SKCM	chr11	114250556	3'UTR	novel		0.14
SKCM	chr11	114064010	Missense_Mutation	NA	G237E	0.5
SKCM	chr11	114156376	Silent	NA	L436L	0.58
SKCM	chr11	114250465	Silent	rs765990632	S644S	0.38
SKCM	chr11	114064097	Missense_Mutation	NA	G266E	0.23
SKCM	chr11	114063414	Silent	novel	I38I	0.18
SKCM	chr11	114064349	Missense_Mutation	NA	S350F	0.35
SKCM	chr11	114064107	Silent	novel	G269G	0.42
SKCM	chr11	114064108	Missense_Mutation	novel	D270N	0.43
SKCM	chr11	114064196	Missense_Mutation	novel	R299Q	0.34
SKCM	chr11	114250580	3'UTR	rs373656983		0.38
SKCM	chr11	114063837	Silent	rs368971745	P179P	0.56
SKCM	chr11	114064549	Missense_Mutation	NA	E417K	0.49
SKCM	chr11	114242325	Missense_Mutation	NA	R538C	0.33	zf-C2H2
SKCM	chr11	114063864	Silent	novel	S188S	0.7
SKCM	chr11	114063985	Silent	rs751396403	L229L	0.33
SKCM	chr11	114064101	Silent	NA	G267G	0.26
SKCM	chr11	114063842	Missense_Mutation	NA	V181G	0.28
SKCM	chr11	114064169	Missense_Mutation	NA	T290I	0.46
SKCM	chr11	114250335	Missense_Mutation	novel	P601L	0.19
SKCM	chr11	114242186	Silent	NA	F491F	0.38
SKCM	chr11	114063771	Silent	NA	F157F	0.34
SKCM	chr11	114247291	Missense_Mutation	NA	P573L	0.15
SKCM	chr11	114063786	Silent	NA	S162S	0.1
SKCM	chr11	114063492	Silent	rs764601942	H64H	0.37
SKCM	chr11	114250410	Missense_Mutation	NA	G626D	0.15
SKCM	chr11	114064179	Silent	novel	R293R	0.2
SKCM	chr11	114187071	Intron	novel		0.27
SKCM	chr11	114063403	Missense_Mutation	NA	D35N	0.58
SKCM	chr11	114063935	Missense_Mutation	NA	S212F	0.07
SKCM	chr11	114250446	Missense_Mutation	NA	Y638C	0.26
SKCM	chr11	114242186	Silent	NA	F491F	0.43
SKCM	chr11	114247296	Missense_Mutation	rs145635689	E575K	0.45
SKCM	chr11	114064327	Missense_Mutation	NA	D343N	0.55
SKCM	chr11	114064256	Missense_Mutation	rs772815592	R319Q	0.35
STAD	chr11	114063403	Missense_Mutation	NA	D35N	0.13
STAD	chr11	114242256	Missense_Mutation	rs758738597	V515M	0.25
STAD	chr11	114064019	Missense_Mutation	NA	E240G	0.15
STAD	chr11	114247362	Missense_Mutation	NA	T597P	0.35
STAD	chr11	114064162	Missense_Mutation	NA	V288I	0.22
STAD	chr11	114187018	Missense_Mutation	NA	T478R	0.16
STAD	chr11	114063457	Missense_Mutation	novel	A53T	0.18
STAD	chr11	114242287	Missense_Mutation	rs762592730	R525H	0.46	zf-C2H2
STAD	chr11	114250531	Silent	NA	T666T	0.32
STAD	chr11	114242259	Missense_Mutation	NA	R516C	0.17
STAD	chr11	114242196	Missense_Mutation	NA	C495G	0.15
STAD	chr11	114247318	Missense_Mutation	NA	K582T	0.07
STAD	chr11	114064523	Missense_Mutation	NA	V408E	0.45
STAD	chr11	114063536	Missense_Mutation	NA	T79S	0.15
STAD	chr11	114063577	Frame_Shift_Ins	novel	*A94Sfs8**	0.3
STAD	chr11	114156387	Missense_Mutation	rs797011179	R440Q	0.24
STAD	chr11	114063388	Missense_Mutation	NA	A30T	0.2
STAD	chr11	114242286	Missense_Mutation	rs748787166	R525C	0.23	zf-C2H2
STAD	chr11	114242255	Silent	rs147709798	G514G	0.26
STAD	chr11	114063651	Silent	NA	Q117Q	0.09
STAD	chr11	114250411	Silent	NA	G626G	0.1
STAD	chr11	114247318	Missense_Mutation	NA	K582T	0.22
UCEC	chr11	114063776	Missense_Mutation	rs771820953	S159L	0.49
UCEC	chr11	114186997	Missense_Mutation	rs761753131	S471L	0.35
UCEC	chr11	114064208	Missense_Mutation	NA	A303V	0.23
UCEC	chr11	114064163	Missense_Mutation	novel	V288A	0.2
UCEC	chr11	114064036	Missense_Mutation	NA	M246V	0.43
UCEC	chr11	114250511	Missense_Mutation	NA	D660N	0.37
UCEC	chr11	114250481	Missense_Mutation	novel	K650E	0.5
UCEC	chr11	114064110	Silent	NA	D270D	0.26
UCEC	chr11	114250566	3'UTR	novel		0.5
UCEC	chr11	114247295	Silent	rs753518284	Y574Y	0.35
UCEC	chr11	114247307	Silent	novel	G578G	0.26
UCEC	chr11	114247349	Missense_Mutation	novel	H592Q	0.37
UCEC	chr11	114064347	Silent	rs200705288	P349P	0.21
UCEC	chr11	114063740	Missense_Mutation	NA	D147G	0.43
UCEC	chr11	114186968	Silent	NA	F461F	0.32
UCEC	chr11	114063493	Missense_Mutation	rs754172517	R65C	0.23
UCEC	chr11	114242215	Missense_Mutation	rs774040543	A501V	0.35
UCEC	chr11	114063228	5'UTR	novel		0.3
UCEC	chr11	114063742	Missense_Mutation	rs368725888	R148C	0.24
UCEC	chr11	114064134	Missense_Mutation	novel	E278D	0.13
UCEC	chr11	114063777	Silent	rs552316073	S159S	0.5
UCEC	chr11	114063316	Missense_Mutation	novel	M6L	0.41
UCEC	chr11	114250530	Missense_Mutation	novel	T666M	0.35
UCEC	chr11	114063752	Missense_Mutation	rs753220958	R151Q	0.34
UCEC	chr11	114063457	Missense_Mutation	novel	A53T	0.55
UCEC	chr11	114242317	Missense_Mutation	NA	R535H	0.26	zf-C2H2
UCEC	chr11	114250324	Splice_Site	NA	X598_splice	0.14
UCEC	chr11	114063288	5'UTR	rs751604008		0.32
UCEC	chr11	114063526	Missense_Mutation	novel	S76P	0.42
UCEC	chr11	114250427	Missense_Mutation	novel	C632R	0.36
UCEC	chr11	114250566	3'UTR	novel		0.44
UCEC	chr11	114250507	Silent	rs757004570	P658P	0.3
UCEC	chr11	114247249	Missense_Mutation	novel	S559N	0.38
UCEC	chr11	114247301	Nonsense_Mutation	novel	C576*	0.37
UCEC	chr11	114063717	Missense_Mutation	novel	D139E	0.15
UCEC	chr11	114064058	Missense_Mutation	novel	S253I	0.14
UCEC	chr11	114064413	Frame_Shift_Ins	NA	*L374Afs42**	0.5
UCEC	chr11	114156360	Missense_Mutation	NA	T431M	0.25
UCEC	chr11	114247358	Silent	NA	V595V	0.27
UCEC	chr11	114063585	Missense_Mutation	novel	K95N	0.23
UCEC	chr11	114063714	Silent	NA	A138A	0.56
UCEC	chr11	114250649	3'UTR	novel		0.33
UCEC	chr11	114064259	Missense_Mutation	NA	P320L	0.24
UCEC	chr11	114242288	Silent	NA	R525R	0.42
UCEC	chr11	114063261	5'UTR	novel		0.41
UCEC	chr11	114063869	Nonsense_Mutation	NA	S190*	0.39
UCEC	chr11	114250510	Silent	rs201532309	P659P	0.31
UCEC	chr11	114063618	Silent	rs367557148	A106A	0.19
UCEC	chr11	114063861	Silent	novel	V187V	0.33
UCEC	chr11	114242180	Silent	rs140189842	A489A	0.23
UCEC	chr11	114064212	Missense_Mutation	novel	E304D	0.5
UCEC	chr11	114063738	Missense_Mutation	novel	E146D	0.34
UCEC	chr11	114064160	Missense_Mutation	novel	S287I	0.36
UCS	chr11	114063245	5'UTR	rs565938914		0.31

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.299	0.00015732
BRCA	DEL	0.4694	7.1709e-58
CESC	DEL	0.5017	1.0762e-32
CHOL	DEL	0.3056	0.048655
ESCA	AMP	0.1033	0.018342
HNSC	DEL	0.4138	1.8879e-21
KIRP	DEL	0.1042	2.839e-05
LIHC	DEL	0.2027	0.00030497
LUAD	DEL	0.1764	4.2393e-06
MESO	DEL	0.2069	0.0023183
PRAD	DEL	0.1016	0.00026046
READ	DEL	0.2	0.054114
SARC	DEL	0.4397	1.8105e-09
SKCM	DEL	0.4768	3.6825e-28
STAD	DEL	0.1678	8.3734e-05
TGCT	DEL	0.7667	0.21504
UCS	DEL	0.4107	0.086462

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.0092	Kaplan-Meier Survival Analysis
MESO	0.00022	Kaplan-Meier Survival Analysis
ACC	0.013	Kaplan-Meier Survival Analysis
SKCM	0.049	Kaplan-Meier Survival Analysis
LUSC	0.00095	Kaplan-Meier Survival Analysis
KIRP	0.0046	Kaplan-Meier Survival Analysis
BLCA	0.014	Kaplan-Meier Survival Analysis
LAML	0.01	Kaplan-Meier Survival Analysis
KICH	0.014	Kaplan-Meier Survival Analysis
LIHC	0.024	Kaplan-Meier Survival Analysis
LGG	0.0034	Kaplan-Meier Survival Analysis
OV	0.0033	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000109906 (Gene tree)
Gene ID: 7704
Gene Symbol: ZBTB16
Alias: PLZF|ZNF145
Full Name: zinc finger and BTB domain containing 16
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 191,098 bases
Position: chr11:114,059,579-114,250,676
Accession: 12930
RBP type: canonical RBP
Summary: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000338157	zf-C2H2	PF00096.26	4.4e-27	1	5
ENSP00000338157	zf-C2H2	PF00096.26	4.4e-27	2	5
ENSP00000338157	zf-C2H2	PF00096.26	4.4e-27	3	5
ENSP00000338157	zf-C2H2	PF00096.26	4.4e-27	4	5
ENSP00000338157	zf-C2H2	PF00096.26	4.4e-27	5	5
ENSP00000376721	zf-C2H2	PF00096.26	4.4e-27	1	5
ENSP00000376721	zf-C2H2	PF00096.26	4.4e-27	2	5
ENSP00000376721	zf-C2H2	PF00096.26	4.4e-27	3	5
ENSP00000376721	zf-C2H2	PF00096.26	4.4e-27	4	5
ENSP00000376721	zf-C2H2	PF00096.26	4.4e-27	5	5
ENSP00000338157	zf-met	PF12874.7	3.3e-13	1	1
ENSP00000376721	zf-met	PF12874.7	3.3e-13	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
14645547	Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression.	Mol Cell Biol	2003 Dec	McConnell MJ	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000392996	ZBTB16-202	2287	-	ENSP00000376721	673 (aa)	-	Q05516
ENST00000535509	ZBTB16-204	727	-	-	- (aa)	-	-
ENST00000535700	ZBTB16-205	572	-	ENSP00000443013	148 (aa)	-	F5H5Y7
ENST00000544220	ZBTB16-208	773	-	ENSP00000437716	115 (aa)	-	F5H6C3
ENST00000335953	ZBTB16-201	2523	XM_017018259	ENSP00000338157	673 (aa)	XP_016873748	Q05516
ENST00000539918	ZBTB16-206	757	-	ENSP00000445047	55 (aa)	-	H0YGW2
ENST00000541602	ZBTB16-207	4427	-	-	- (aa)	-	-
ENST00000545851	ZBTB16-209	534	-	-	- (aa)	-	-
ENST00000535379	ZBTB16-203	705	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000109906's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05200	Pathways in cancer	KEGG
hsa05202	Transcriptional misregulation in cancer	KEGG
hsa05221	Acute myeloid leukemia	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000109906	Fibrinogen	3.061e-005	-
ENSG00000109906	Arteries	3.6080000E-005	-
ENSG00000109906	Blood Pressure	6.5090000E-006	-
ENSG00000109906	Blood Glucose	4.0710000E-005	-
ENSG00000109906	Potassium	5.1910000E-005	-
ENSG00000109906	Platelet Function Tests	9.4790135E-006	-
ENSG00000109906	Platelet Function Tests	4.4890126E-006	-
ENSG00000109906	Platelet Function Tests	6.2554659E-006	-
ENSG00000109906	Child Development Disorders, Pervasive	3.4047600E-005	-
ENSG00000109906	Child Development Disorders, Pervasive	2.1157100E-005	-
ENSG00000109906	Child Development Disorders, Pervasive	2.5108700E-005	-
ENSG00000109906	Child Development Disorders, Pervasive	5.6316500E-007	-
ENSG00000109906	Child Development Disorders, Pervasive	1.1437700E-005	-
ENSG00000109906	Child Development Disorders, Pervasive	1.8710000E-006	-
ENSG00000109906	Child Development Disorders, Pervasive	2.9485800E-005	-
ENSG00000109906	Child Development Disorders, Pervasive	2.0462200E-006	-
ENSG00000109906	Child Development Disorders, Pervasive	1.0554000E-005	-
ENSG00000109906	Conduct Disorder	9E-6	18846501
ENSG00000109906	Gestational Age	7E-7	27490719
ENSG00000109906	Live Birth	7E-7	27490719
ENSG00000109906	Asthma	2E-7	25918132
ENSG00000109906	Toluene 2,4-Diisocyanate	2E-7	25918132
ENSG00000109906	Glioma	6E-11	26424050

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000109906	rs73000929	11	114082900	A	Mean platelet volume	27863252	[0.065-0.103] unit increase	0.08359863	EFO_0004584
ENSG00000109906	rs17116384	11	114110519	G	Mean platelet volume	27863252	[0.021-0.036] unit increase	0.02840606	EFO_0004584
ENSG00000109906	rs585287	11	114173717	A	Gestational age at birth in premature rupture of membrane-initiated deliveries (maternal effect)	27490719			EFO_0005112\|EFO_0006921
ENSG00000109906	rs648044	11	114160077	T	Non-glioblastoma glioma	26424050	[1.17-1.34]	1.25	EFO_0000326
ENSG00000109906	rs17116334	11	114091040	T	Conduct disorder (maternal expressed emotions interaction)	18846501	[NR] unit increase	1.3	EFO_0008342\|EFO_0004216
ENSG00000109906	rs3214101	11	114138686	A	Corneal astigmatism	29422769	[1.05-1.12]	1.08	EFO_1002040
ENSG00000109906	rs1784692	11	114078510	T	Polycystic ovary syndrome	26284813	[1.19-1.61]	1.39	EFO_0000660
ENSG00000109906	rs648044	11	114160077	A	Educational attainment (MTAG)	30038396	[0.0049-0.0103] unit increase	0.0076	EFO_0004784
ENSG00000109906	rs17116545	11	114156555	G	Eotaxin levels	27989323	[0.13-0.32] SD units increase	0.2246	EFO_0008122
ENSG00000109906	rs2846630	11	114086475	A	Granulocyte percentage of myeloid white cells	27863252	[0.029-0.043] unit increase	0.03588733	EFO_0007997
ENSG00000109906	rs2846630	11	114086475	A	Myeloid white cell count	27863252	[0.017-0.031] unit increase	0.02398292	EFO_0007988
ENSG00000109906	rs238914	11	114113387	A	Myeloid white cell count	27863252	[0.018-0.033] unit increase	0.0254177	EFO_0007988
ENSG00000109906	rs73000929	11	114082900	A	Platelet count	27863252	[0.073-0.111] unit decrease	0.09191479	EFO_0004309
ENSG00000109906	rs73000965	11	114111599	A	Platelet count	27863252	[0.02-0.036] unit decrease	0.02813931	EFO_0004309
ENSG00000109906	rs2846630	11	114086475	A	White blood cell count	27863252	[0.016-0.031] unit increase	0.02367011	EFO_0004308
ENSG00000109906	rs238914	11	114113387	A	White blood cell count	27863252	[0.016-0.03] unit increase	0.02325923	EFO_0004308
ENSG00000109906	rs648044	11	114160077	A	Non-glioblastoma glioma	28346443	1.13-1.25	1.19	EFO_0000326\|EFO_0005543
ENSG00000109906	rs2846630	11	114086475	A	Monocyte percentage of white cells	27863252	[0.027-0.042] unit decrease	0.03465779	EFO_0007989
ENSG00000109906	rs77669868	11	114169672	G	Monocyte percentage of white cells	27863252	[0.02-0.039] unit decrease	0.02964656	EFO_0007989
ENSG00000109906	rs2846630	11	114086475	A	Neutrophil count	27863252	[0.019-0.034] unit increase	0.02675765	EFO_0004833
ENSG00000109906	rs238914	11	114113387	A	Neutrophil count	27863252	[0.019-0.033] unit increase	0.02624385	EFO_0004833
ENSG00000109906	rs73000929	11	114082900	A	Plateletcrit	27863252	[0.04-0.079] unit decrease	0.0597131	EFO_0007985
ENSG00000109906	rs2846630	11	114086475	A	Granulocyte count	27863252	[0.019-0.034] unit increase	0.0266233	EFO_0007987
ENSG00000109906	rs238914	11	114113387	A	Granulocyte count	27863252	[0.019-0.033] unit increase	0.02588001	EFO_0007987
ENSG00000109906	rs2846630	11	114086475	A	Sum neutrophil eosinophil counts	27863252	[0.019-0.034] unit increase	0.0264614	EFO_0004833\|EFO_0004842
ENSG00000109906	rs238914	11	114113387	A	Sum neutrophil eosinophil counts	27863252	[0.019-0.033] unit increase	0.02592514	EFO_0004833\|EFO_0004842
ENSG00000109906	rs2846630	11	114086475	A	Sum basophil neutrophil counts	27863252	[0.019-0.034] unit increase	0.02681876	EFO_0004833\|EFO_0005090
ENSG00000109906	rs238914	11	114113387	A	Sum basophil neutrophil counts	27863252	[0.019-0.033] unit increase	0.02619009	EFO_0004833\|EFO_0005090
ENSG00000109906	rs1672691	11	114071429	A	Diisocyanate-induced asthma	25918132	[1.76-3.55]	2.5	EFO_0006995\|EFO_0000270
ENSG00000109906	rs629922	11	114194103	C	Paneth cell defects in Crohn's disease	28352666	unit increase	4.142	EFO_0007963\|EFO_0000384
ENSG00000109906	rs648044	11	114160077	A	Educational attainment (years of education)	30038396	[0.0054-0.0112] unit increase	0.0083	EFO_0004784
ENSG00000109906	rs1784692	11	114078510	T	Polycystic ovary syndrome	30566500	[0.1-0.188] unit increase	0.1438	EFO_0000660
ENSG00000109906	rs636406	11	114160370	?	Lung function (FVC)	30595370			EFO_0004312
ENSG00000109906	rs513249	11	114161870	?	Body mass index	30595370			EFO_0004340
ENSG00000109906	rs10891630	11	114140943	?	Morning person	30595370			EFO_0008328
ENSG00000109906	rs17116384	11	114110519	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000109906	rs238913	11	114113767	?	White blood cell count	30595370			EFO_0004308
ENSG00000109906	rs17116384	11	114110519	?	Red blood cell count	30595370			EFO_0004305
ENSG00000109906	rs238925	11	114104625	T	Age of smoking initiation (MTAG)	30643251	[0.0056-0.0114] unit increase	0.00849747	EFO_0005670
ENSG00000109906	rs238910	11	114116157	G	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0064-0.0107] unit decrease	0.00858535	EFO_0006527
ENSG00000109906	rs238896	11	114123783	A	Smoking initiation (ever regular vs never regular)	30643251	[0.012-0.022] unit decrease	0.016867377	EFO_0006527
ENSG00000109906	rs4936290	11	114138533	C	Chronotype	30696823		1.0231643	EFO_0008328

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000109906's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000109906	ZBTB16	100	87.162	ENSAPOG00000017643	zbtb16a	100	76.401	Acanthochromis_polyacanthus
ENSG00000109906	ZBTB16	88	80.198	ENSAPOG00000020415	zbtb16b	100	59.795	Acanthochromis_polyacanthus
ENSG00000109906	ZBTB16	100	100.000	ENSAMEG00000013292	ZBTB16	100	97.474	Ailuropoda_melanoleuca
ENSG00000109906	ZBTB16	100	87.162	ENSACIG00000012478	zbtb16a	100	76.071	Amphilophus_citrinellus
ENSG00000109906	ZBTB16	99	71.918	ENSACIG00000006854	zbtb16b	99	60.148	Amphilophus_citrinellus
ENSG00000109906	ZBTB16	97	72.028	ENSAOCG00000022870	-	100	59.795	Amphiprion_ocellaris
ENSG00000109906	ZBTB16	100	87.162	ENSAPEG00000000983	zbtb16a	100	76.514	Amphiprion_percula
ENSG00000109906	ZBTB16	88	80.198	ENSAPEG00000007796	zbtb16b	100	59.503	Amphiprion_percula
ENSG00000109906	ZBTB16	100	86.486	ENSATEG00000001020	zbtb16a	100	76.071	Anabas_testudineus
ENSG00000109906	ZBTB16	97	73.427	ENSATEG00000021683	zbtb16b	100	60.656	Anabas_testudineus
ENSG00000109906	ZBTB16	100	97.391	ENSAPLG00000002963	ZBTB16	100	86.776	Anas_platyrhynchos
ENSG00000109906	ZBTB16	100	100.000	ENSANAG00000029870	ZBTB16	100	98.960	Aotus_nancymaae
ENSG00000109906	ZBTB16	100	87.162	ENSACLG00000021957	zbtb16a	100	75.994	Astatotilapia_calliptera
ENSG00000109906	ZBTB16	100	83.784	ENSAMXG00000009872	zbtb16b	100	71.386	Astyanax_mexicanus
ENSG00000109906	ZBTB16	100	87.333	ENSAMXG00000005918	zbtb16a	100	78.088	Astyanax_mexicanus
ENSG00000109906	ZBTB16	100	100.000	ENSBTAG00000011266	ZBTB16	100	96.137	Bos_taurus
ENSG00000109906	ZBTB16	100	100.000	ENSCJAG00000011978	ZBTB16	100	99.108	Callithrix_jacchus
ENSG00000109906	ZBTB16	100	100.000	ENSCAFG00000013538	ZBTB16	100	95.988	Canis_familiaris
ENSG00000109906	ZBTB16	100	100.000	ENSCAFG00020002582	ZBTB16	100	95.988	Canis_lupus_dingo
ENSG00000109906	ZBTB16	100	100.000	ENSCHIG00000008305	ZBTB16	100	96.434	Capra_hircus
ENSG00000109906	ZBTB16	100	100.000	ENSTSYG00000007602	ZBTB16	100	98.217	Carlito_syrichta
ENSG00000109906	ZBTB16	100	99.130	ENSCAPG00000008806	ZBTB16	100	97.177	Cavia_aperea
ENSG00000109906	ZBTB16	100	99.130	ENSCPOG00000004151	ZBTB16	100	97.177	Cavia_porcellus
ENSG00000109906	ZBTB16	100	100.000	ENSCCAG00000001377	ZBTB16	100	99.108	Cebus_capucinus
ENSG00000109906	ZBTB16	100	100.000	ENSCATG00000039272	ZBTB16	100	99.257	Cercocebus_atys
ENSG00000109906	ZBTB16	100	100.000	ENSCLAG00000014819	ZBTB16	100	97.177	Chinchilla_lanigera
ENSG00000109906	ZBTB16	100	100.000	ENSCSAG00000002761	ZBTB16	100	99.406	Chlorocebus_sabaeus
ENSG00000109906	ZBTB16	100	100.000	ENSCHOG00000003888	ZBTB16	100	84.473	Choloepus_hoffmanni
ENSG00000109906	ZBTB16	100	96.522	ENSCPBG00000009377	ZBTB16	100	79.346	Chrysemys_picta_bellii
ENSG00000109906	ZBTB16	100	100.000	ENSCANG00000024434	ZBTB16	100	99.554	Colobus_angolensis_palliatus
ENSG00000109906	ZBTB16	100	100.000	ENSCGRG00001024806	Zbtb16	100	96.731	Cricetulus_griseus_chok1gshd
ENSG00000109906	ZBTB16	100	88.514	ENSCSEG00000016440	zbtb16a	100	75.775	Cynoglossus_semilaevis
ENSG00000109906	ZBTB16	88	80.198	ENSCSEG00000015300	zbtb16b	100	59.496	Cynoglossus_semilaevis
ENSG00000109906	ZBTB16	100	70.946	ENSCVAG00000020238	zbtb16b	100	57.143	Cyprinodon_variegatus
ENSG00000109906	ZBTB16	100	88.514	ENSCVAG00000007140	zbtb16a	100	76.401	Cyprinodon_variegatus
ENSG00000109906	ZBTB16	100	89.865	ENSDARG00000007184	zbtb16a	100	78.940	Danio_rerio
ENSG00000109906	ZBTB16	100	87.838	ENSDARG00000074526	zbtb16b	100	71.598	Danio_rerio
ENSG00000109906	ZBTB16	100	100.000	ENSDNOG00000047356	ZBTB16	100	97.325	Dasypus_novemcinctus
ENSG00000109906	ZBTB16	100	98.261	ENSDORG00000011901	Zbtb16	100	96.137	Dipodomys_ordii
ENSG00000109906	ZBTB16	100	100.000	ENSETEG00000001379	ZBTB16	100	95.840	Echinops_telfairi
ENSG00000109906	ZBTB16	94	62.727	ENSEBUG00000011359	zbtb16a	93	38.949	Eptatretus_burgeri
ENSG00000109906	ZBTB16	100	100.000	ENSEASG00005006684	ZBTB16	100	97.920	Equus_asinus_asinus
ENSG00000109906	ZBTB16	100	100.000	ENSECAG00000024358	ZBTB16	100	98.068	Equus_caballus
ENSG00000109906	ZBTB16	100	96.522	ENSELUG00000014779	zbtb16a	100	77.647	Esox_lucius
ENSG00000109906	ZBTB16	100	100.000	ENSFCAG00000026205	ZBTB16	100	96.880	Felis_catus
ENSG00000109906	ZBTB16	100	96.522	ENSFALG00000010031	ZBTB16	100	83.529	Ficedula_albicollis
ENSG00000109906	ZBTB16	100	100.000	ENSFDAG00000008006	ZBTB16	100	97.189	Fukomys_damarensis
ENSG00000109906	ZBTB16	98	73.793	ENSFHEG00000003322	zbtb16b	100	59.590	Fundulus_heteroclitus
ENSG00000109906	ZBTB16	100	88.514	ENSFHEG00000021769	zbtb16a	100	75.959	Fundulus_heteroclitus
ENSG00000109906	ZBTB16	90	79.808	ENSGMOG00000005711	-	83	82.400	Gadus_morhua
ENSG00000109906	ZBTB16	100	86.486	ENSGMOG00000012795	zbtb16a	99	71.679	Gadus_morhua
ENSG00000109906	ZBTB16	100	97.391	ENSGALG00000038540	ZBTB16	100	86.776	Gallus_gallus
ENSG00000109906	ZBTB16	88	80.198	ENSGAFG00000013252	zbtb16b	100	59.297	Gambusia_affinis
ENSG00000109906	ZBTB16	100	86.486	ENSGAFG00000010259	zbtb16a	100	75.811	Gambusia_affinis
ENSG00000109906	ZBTB16	100	87.838	ENSGACG00000020771	zbtb16a	100	72.767	Gasterosteus_aculeatus
ENSG00000109906	ZBTB16	99	73.288	ENSGACG00000010711	zbtb16b	99	59.884	Gasterosteus_aculeatus
ENSG00000109906	ZBTB16	100	96.522	ENSGAGG00000014176	ZBTB16	100	84.844	Gopherus_agassizii
ENSG00000109906	ZBTB16	100	100.000	ENSGGOG00000000319	ZBTB16	100	99.554	Gorilla_gorilla
ENSG00000109906	ZBTB16	100	87.162	ENSHBUG00000012173	zbtb16a	100	75.994	Haplochromis_burtoni
ENSG00000109906	ZBTB16	99	71.918	ENSHBUG00000018502	-	99	60.296	Haplochromis_burtoni
ENSG00000109906	ZBTB16	100	100.000	ENSHGLG00000007562	ZBTB16	100	97.623	Heterocephalus_glaber_female
ENSG00000109906	ZBTB16	100	100.000	ENSHGLG00100005892	ZBTB16	100	97.189	Heterocephalus_glaber_male
ENSG00000109906	ZBTB16	100	86.486	ENSHCOG00000010142	zbtb16a	100	74.415	Hippocampus_comes
ENSG00000109906	ZBTB16	88	81.188	ENSHCOG00000001662	zbtb16b	100	60.682	Hippocampus_comes
ENSG00000109906	ZBTB16	92	91.509	ENSIPUG00000013283	zbtb16b	99	70.501	Ictalurus_punctatus
ENSG00000109906	ZBTB16	100	96.522	ENSIPUG00000000764	zbtb16	100	76.730	Ictalurus_punctatus
ENSG00000109906	ZBTB16	100	100.000	ENSSTOG00000003580	ZBTB16	100	97.771	Ictidomys_tridecemlineatus
ENSG00000109906	ZBTB16	100	100.000	ENSJJAG00000019821	Zbtb16	100	96.285	Jaculus_jaculus
ENSG00000109906	ZBTB16	100	89.189	ENSKMAG00000017553	zbtb16a	100	75.258	Kryptolebias_marmoratus
ENSG00000109906	ZBTB16	97	72.028	ENSKMAG00000013166	zbtb16b	100	60.327	Kryptolebias_marmoratus
ENSG00000109906	ZBTB16	97	72.727	ENSLBEG00000022299	zbtb16b	100	60.444	Labrus_bergylta
ENSG00000109906	ZBTB16	100	87.838	ENSLBEG00000009528	zbtb16a	100	74.336	Labrus_bergylta
ENSG00000109906	ZBTB16	96	65.455	ENSLACG00000001777	-	99	43.447	Latimeria_chalumnae
ENSG00000109906	ZBTB16	100	96.522	ENSLOCG00000004636	zbtb16a	100	80.854	Lepisosteus_oculatus
ENSG00000109906	ZBTB16	100	100.000	ENSLAFG00000014626	ZBTB16	100	97.028	Loxodonta_africana
ENSG00000109906	ZBTB16	100	100.000	ENSMFAG00000008415	ZBTB16	100	99.554	Macaca_fascicularis
ENSG00000109906	ZBTB16	100	100.000	ENSMMUG00000007085	ZBTB16	100	99.554	Macaca_mulatta
ENSG00000109906	ZBTB16	100	100.000	ENSMNEG00000037837	ZBTB16	100	99.554	Macaca_nemestrina
ENSG00000109906	ZBTB16	100	100.000	ENSMLEG00000027152	ZBTB16	100	99.554	Mandrillus_leucophaeus
ENSG00000109906	ZBTB16	100	86.486	ENSMAMG00000002542	zbtb16a	100	76.401	Mastacembelus_armatus
ENSG00000109906	ZBTB16	88	81.188	ENSMAMG00000017518	zbtb16b	100	60.234	Mastacembelus_armatus
ENSG00000109906	ZBTB16	100	87.162	ENSMZEG00005010471	zbtb16a	98	73.510	Maylandia_zebra
ENSG00000109906	ZBTB16	99	71.918	ENSMZEG00005005843	zbtb16b	99	60.296	Maylandia_zebra
ENSG00000109906	ZBTB16	100	97.391	ENSMGAG00000002967	ZBTB16	100	87.073	Meleagris_gallopavo
ENSG00000109906	ZBTB16	100	100.000	ENSMAUG00000010982	Zbtb16	100	84.101	Mesocricetus_auratus
ENSG00000109906	ZBTB16	100	100.000	ENSMICG00000010072	ZBTB16	100	98.514	Microcebus_murinus
ENSG00000109906	ZBTB16	100	100.000	ENSMOCG00000001402	Zbtb16	100	96.285	Microtus_ochrogaster
ENSG00000109906	ZBTB16	95	70.213	ENSMMOG00000014257	zbtb16b	100	58.876	Mola_mola
ENSG00000109906	ZBTB16	92	95.283	ENSMMOG00000014733	zbtb16a	100	76.106	Mola_mola
ENSG00000109906	ZBTB16	100	100.000	ENSMODG00000014130	ZBTB16	100	91.988	Monodelphis_domestica
ENSG00000109906	ZBTB16	100	85.811	ENSMALG00000012920	zbtb16a	100	76.000	Monopterus_albus
ENSG00000109906	ZBTB16	100	100.000	ENSMUSG00000066687	Zbtb16	100	96.731	Mus_musculus
ENSG00000109906	ZBTB16	100	100.000	MGP_PahariEiJ_G0015038	Zbtb16	100	96.434	Mus_pahari
ENSG00000109906	ZBTB16	100	100.000	MGP_SPRETEiJ_G0033309	Zbtb16	100	96.731	Mus_spretus
ENSG00000109906	ZBTB16	100	100.000	ENSMPUG00000003929	ZBTB16	100	96.731	Mustela_putorius_furo
ENSG00000109906	ZBTB16	100	99.130	ENSMLUG00000002970	ZBTB16	100	95.111	Myotis_lucifugus
ENSG00000109906	ZBTB16	100	100.000	ENSNGAG00000016604	Zbtb16	100	97.474	Nannospalax_galili
ENSG00000109906	ZBTB16	97	72.028	ENSNBRG00000021111	zbtb16b	100	59.562	Neolamprologus_brichardi
ENSG00000109906	ZBTB16	100	87.162	ENSNBRG00000011170	zbtb16a	100	75.994	Neolamprologus_brichardi
ENSG00000109906	ZBTB16	100	100.000	ENSNLEG00000007319	ZBTB16	100	99.554	Nomascus_leucogenys
ENSG00000109906	ZBTB16	100	100.000	ENSOPRG00000012302	-	100	91.840	Ochotona_princeps
ENSG00000109906	ZBTB16	100	100.000	ENSODEG00000012587	ZBTB16	100	96.731	Octodon_degus
ENSG00000109906	ZBTB16	97	72.028	ENSONIG00000011103	zbtb16b	100	59.503	Oreochromis_niloticus
ENSG00000109906	ZBTB16	100	87.162	ENSONIG00000009495	zbtb16a	100	75.994	Oreochromis_niloticus
ENSG00000109906	ZBTB16	100	100.000	ENSOCUG00000007470	ZBTB16	100	97.028	Oryctolagus_cuniculus
ENSG00000109906	ZBTB16	92	95.283	ENSORLG00000014640	zbtb16	100	75.735	Oryzias_latipes
ENSG00000109906	ZBTB16	92	95.283	ENSORLG00020010135	zbtb16	100	75.735	Oryzias_latipes_hni
ENSG00000109906	ZBTB16	92	95.283	ENSORLG00015016751	zbtb16	100	75.735	Oryzias_latipes_hsok
ENSG00000109906	ZBTB16	92	95.283	ENSOMEG00000002434	zbtb16a	100	75.588	Oryzias_melastigma
ENSG00000109906	ZBTB16	99	73.826	ENSOMEG00000000112	zbtb16b	100	59.854	Oryzias_melastigma
ENSG00000109906	ZBTB16	100	100.000	ENSOGAG00000033673	ZBTB16	100	98.663	Otolemur_garnettii
ENSG00000109906	ZBTB16	100	100.000	ENSPPAG00000034578	ZBTB16	100	99.554	Pan_paniscus
ENSG00000109906	ZBTB16	100	100.000	ENSPPRG00000002582	ZBTB16	100	96.731	Panthera_pardus
ENSG00000109906	ZBTB16	100	100.000	ENSPTIG00000009078	ZBTB16	100	93.314	Panthera_tigris_altaica
ENSG00000109906	ZBTB16	100	100.000	ENSPTRG00000004302	ZBTB16	100	99.554	Pan_troglodytes
ENSG00000109906	ZBTB16	100	100.000	ENSPANG00000005924	ZBTB16	100	99.554	Papio_anubis
ENSG00000109906	ZBTB16	92	95.283	ENSPKIG00000008755	zbtb16a	100	79.351	Paramormyrops_kingsleyae
ENSG00000109906	ZBTB16	100	96.522	ENSPSIG00000006603	ZBTB16	100	86.478	Pelodiscus_sinensis
ENSG00000109906	ZBTB16	90	80.769	ENSPMGG00000011276	zbtb16b	99	58.222	Periophthalmus_magnuspinnatus
ENSG00000109906	ZBTB16	100	86.486	ENSPMGG00000008445	zbtb16a	100	75.444	Periophthalmus_magnuspinnatus
ENSG00000109906	ZBTB16	100	100.000	ENSPEMG00000008489	Zbtb16	100	96.880	Peromyscus_maniculatus_bairdii
ENSG00000109906	ZBTB16	86	66.923	ENSPMAG00000002911	zbtb16a	99	50.742	Petromyzon_marinus
ENSG00000109906	ZBTB16	100	100.000	ENSPCIG00000011217	ZBTB16	100	92.285	Phascolarctos_cinereus
ENSG00000109906	ZBTB16	100	86.486	ENSPFOG00000016496	zbtb16a	100	75.664	Poecilia_formosa
ENSG00000109906	ZBTB16	88	80.198	ENSPFOG00000005512	zbtb16b	100	59.297	Poecilia_formosa
ENSG00000109906	ZBTB16	88	80.198	ENSPLAG00000021831	zbtb16b	100	59.444	Poecilia_latipinna
ENSG00000109906	ZBTB16	88	80.198	ENSPMEG00000022510	zbtb16b	100	59.444	Poecilia_mexicana
ENSG00000109906	ZBTB16	100	86.486	ENSPREG00000015369	zbtb16a	100	75.369	Poecilia_reticulata
ENSG00000109906	ZBTB16	88	79.208	ENSPREG00000010666	zbtb16b	100	59.151	Poecilia_reticulata
ENSG00000109906	ZBTB16	100	100.000	ENSPPYG00000003891	ZBTB16	99	99.666	Pongo_abelii
ENSG00000109906	ZBTB16	100	100.000	ENSPCAG00000008544	ZBTB16	100	89.896	Procavia_capensis
ENSG00000109906	ZBTB16	100	100.000	ENSPCOG00000004404	ZBTB16	100	98.960	Propithecus_coquereli
ENSG00000109906	ZBTB16	100	100.000	ENSPVAG00000005291	ZBTB16	100	97.152	Pteropus_vampyrus
ENSG00000109906	ZBTB16	99	71.918	ENSPNYG00000015514	zbtb16b	99	60.296	Pundamilia_nyererei
ENSG00000109906	ZBTB16	100	87.162	ENSPNYG00000010616	zbtb16a	100	75.847	Pundamilia_nyererei
ENSG00000109906	ZBTB16	92	91.509	ENSPNAG00000012205	zbtb16b	100	71.598	Pygocentrus_nattereri
ENSG00000109906	ZBTB16	100	96.522	ENSPNAG00000014782	zbtb16a	100	79.087	Pygocentrus_nattereri
ENSG00000109906	ZBTB16	100	100.000	ENSRNOG00000029980	Zbtb16	100	96.137	Rattus_norvegicus
ENSG00000109906	ZBTB16	100	100.000	ENSRBIG00000035195	ZBTB16	100	99.554	Rhinopithecus_bieti
ENSG00000109906	ZBTB16	100	100.000	ENSRROG00000036987	ZBTB16	100	99.554	Rhinopithecus_roxellana
ENSG00000109906	ZBTB16	100	100.000	ENSSBOG00000032604	ZBTB16	100	98.960	Saimiri_boliviensis_boliviensis
ENSG00000109906	ZBTB16	100	100.000	ENSSHAG00000009882	ZBTB16	100	91.543	Sarcophilus_harrisii
ENSG00000109906	ZBTB16	96	77.465	ENSSFOG00015002679	-	100	64.083	Scleropages_formosus
ENSG00000109906	ZBTB16	99	89.116	ENSSFOG00015010445	zbtb16	100	78.139	Scleropages_formosus
ENSG00000109906	ZBTB16	88	81.188	ENSSMAG00000007679	zbtb16b	100	59.704	Scophthalmus_maximus
ENSG00000109906	ZBTB16	100	88.514	ENSSMAG00000016425	zbtb16a	97	70.561	Scophthalmus_maximus
ENSG00000109906	ZBTB16	97	72.727	ENSSDUG00000012745	zbtb16b	100	59.913	Seriola_dumerili
ENSG00000109906	ZBTB16	100	87.838	ENSSDUG00000021980	zbtb16a	100	76.696	Seriola_dumerili
ENSG00000109906	ZBTB16	100	87.838	ENSSLDG00000002956	zbtb16a	100	76.696	Seriola_lalandi_dorsalis
ENSG00000109906	ZBTB16	99	72.603	ENSSLDG00000006197	zbtb16b	99	59.971	Seriola_lalandi_dorsalis
ENSG00000109906	ZBTB16	99	71.918	ENSSPAG00000021453	zbtb16b	100	61.012	Stegastes_partitus
ENSG00000109906	ZBTB16	100	87.838	ENSSPAG00000018743	zbtb16a	100	76.219	Stegastes_partitus
ENSG00000109906	ZBTB16	100	100.000	ENSSSCG00000030095	ZBTB16	100	97.771	Sus_scrofa
ENSG00000109906	ZBTB16	92	58.454	ENSTRUG00000006950	zbtb16b	100	58.454	Takifugu_rubripes
ENSG00000109906	ZBTB16	100	85.811	ENSTRUG00000002959	zbtb16a	100	75.000	Takifugu_rubripes
ENSG00000109906	ZBTB16	92	73.529	ENSTNIG00000016189	zbtb16b	100	59.880	Tetraodon_nigroviridis
ENSG00000109906	ZBTB16	95	73.077	ENSTNIG00000005798	zbtb16a	100	76.375	Tetraodon_nigroviridis
ENSG00000109906	ZBTB16	100	100.000	ENSTBEG00000016863	ZBTB16	100	88.972	Tupaia_belangeri
ENSG00000109906	ZBTB16	100	100.000	ENSTTRG00000001510	ZBTB16	100	96.582	Tursiops_truncatus
ENSG00000109906	ZBTB16	100	100.000	ENSUMAG00000003782	ZBTB16	100	97.028	Ursus_maritimus
ENSG00000109906	ZBTB16	100	100.000	ENSVVUG00000016272	ZBTB16	100	96.137	Vulpes_vulpes
ENSG00000109906	ZBTB16	92	92.453	ENSXETG00000033139	ZBTB16	100	78.190	Xenopus_tropicalis
ENSG00000109906	ZBTB16	100	86.486	ENSXMAG00000008853	zbtb16a	100	75.628	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	12802276.	IDA	Process
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	12802276.	IDA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	12802276.	IDA	Function
GO:0001823	mesonephros development	8541544.	ISS	Process
GO:0003677	DNA binding	12802276.	IDA	Function
GO:0003677	DNA binding	9294197.	NAS	Function
GO:0003700	DNA-binding transcription factor activity	21873635.	IBA	Function
GO:0005515	protein binding	9294197.10980608.16169070.16189514.16676348.16828757.17118363.19648967.21988832.23088713.24359566.25241761.25416956.26871637.27107012.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	9294197.11929873.21547890.24359566.	IDA	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0006915	apoptotic process	9294197.	NAS	Process
GO:0007417	central nervous system development	8541544.	ISS	Process
GO:0008022	protein C-terminus binding	-	IEA	Function
GO:0008285	negative regulation of cell proliferation	-	IEA	Process
GO:0009880	embryonic pattern specification	-	IEA	Process
GO:0009952	anterior/posterior pattern specification	-	IEA	Process
GO:0016567	protein ubiquitination	-	IEA	Process
GO:0016604	nuclear body	19648967.24359566.	IDA	Component
GO:0016605	PML body	9294197.	IDA	Component
GO:0016607	nuclear speck	8541544.	IDA	Component
GO:0017053	transcriptional repressor complex	12802276.	IDA	Component
GO:0019904	protein domain specific binding	-	IEA	Function
GO:0030097	hemopoiesis	8541544.	IDA	Process
GO:0030097	hemopoiesis	9294197.	TAS	Process
GO:0030099	myeloid cell differentiation	9294197.	TAS	Process
GO:0032332	positive regulation of chondrocyte differentiation	21547890.	IMP	Process
GO:0032991	protein-containing complex	10980608.	IMP	Component
GO:0034504	protein localization to nucleus	-	IEA	Process
GO:0035116	embryonic hindlimb morphogenesis	-	IEA	Process
GO:0035136	forelimb morphogenesis	-	IEA	Process
GO:0042733	embryonic digit morphogenesis	-	IEA	Process
GO:0042802	identical protein binding	9294197.25416956.27107012.	IPI	Function
GO:0042803	protein homodimerization activity	8622986.	IDA	Function
GO:0043065	positive regulation of apoptotic process	-	IEA	Process
GO:0043565	sequence-specific DNA binding	21873635.	IBA	Function
GO:0043687	post-translational protein modification	-	TAS	Process
GO:0045600	positive regulation of fat cell differentiation	21547890.	IMP	Process
GO:0045638	negative regulation of myeloid cell differentiation	8541544.	ISS	Process
GO:0045778	positive regulation of ossification	21547890.	IDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0045892	negative regulation of transcription, DNA-templated	12802276.24359566.	IDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	9294197.	NAS	Process
GO:0045893	positive regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0045893	positive regulation of transcription, DNA-templated	21547890.	IDA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0048133	male germ-line stem cell asymmetric division	-	IEA	Process
GO:0051138	positive regulation of NK T cell differentiation	-	IEA	Process
GO:0051216	cartilage development	21547890.	IDA	Process
GO:0061036	positive regulation of cartilage development	21547890.	IDA	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

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Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.