EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26265695	Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.	Blood	2015 Sep 17	Sperlazza J	doi: 10.1182/blood-2015-03-631606
23708667	The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.	Oncogene	2014 Apr 24	Cai Y	doi: 10.1038/onc.2013.178
25407497	Association of the chromodomain helicase DNA-binding protein 4 (CHD4) missense variation p.D140E with cancer: potential interaction with smoking.	Genes Chromosomes Cancer	2015 Feb	Yamada M	doi: 10.1002/gcc.22227
29305962	CHD4-mediated loss of E-cadherin determines metastatic ability in triple-negative breast cancer cells.	Exp Cell Res	2018 Feb 1	Luo CW	doi: 10.1016/j.yexcr.2017.12.032
17694084	The human Mi-2/NuRD complex and gene regulation.	Oncogene	2007 Aug 13	Denslow SA	-
25737278	Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4.	Genes Dev	2015 Mar 1	Guillemette S	doi: 10.1101/gad.256214.114.
26095183	Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma.	J Hepatol	2015 Nov	Nio K	doi: 10.1016/j.jhep.2015.06.009
27779108	RNAi screens identify CHD4 as an essential gene in breast cancer growth.	Oncotarget	2016 Dec 6	D'Alesio C	doi: 10.18632/oncotarget.12646.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr12	6570960	Missense_Mutation	NA	R1877Q	0.12
BLCA	chr12	6577820	Missense_Mutation	NA	E1776Q	0.08
BLCA	chr12	6599982	Missense_Mutation	novel	E425Q	0.23
BLCA	chr12	6573208	Nonsense_Mutation	novel	S1808*	0.09
BLCA	chr12	6591584	Splice_Site	NA	X1075_splice	0.43
BLCA	chr12	6598063	Frame_Shift_Del	novel	*Y574Sfs43**	0.29
BLCA	chr12	6582149	Silent	novel	L1501L	0.18
BLCA	chr12	6583132	Intron	novel		0.14
BLCA	chr12	6598012	Missense_Mutation	novel	E592K	0.06
BLCA	chr12	6600303	Missense_Mutation	novel	D386H	0.11
BLCA	chr12	6600939	Missense_Mutation	rs760698915	R305H	0.48
BLCA	chr12	6581084	Silent	NA	V1623V	0.21
BLCA	chr12	6593576	Missense_Mutation	novel	S785C	0.21	ResIII
BLCA	chr12	6598290	Missense_Mutation	NA	E540K	0.54
BLCA	chr12	6600274	Silent	novel	V395V	0.29
BLCA	chr12	6581709	Missense_Mutation	NA	P1541A	0.22
BLCA	chr12	6582943	Splice_Region	novel		0.29
BLCA	chr12	6583261	Missense_Mutation	NA	L1333V	0.34
BLCA	chr12	6582924	Missense_Mutation	NA	P1387L	0.16
BLCA	chr12	6583063	Missense_Mutation	NA	E1371Q	0.21
BLCA	chr12	6583363	Missense_Mutation	NA	E1299Q	0.19
BLCA	chr12	6582959	Intron	rs768105598		0.18
BLCA	chr12	6594518	Missense_Mutation	novel	E752K	0.2	ResIII
BLCA	chr12	6582247	Missense_Mutation	NA	E1469Q	0.14
BLCA	chr12	6582668	Silent	novel	F1439F	0.26
BLCA	chr12	6606305	Silent	novel	L23L	0.41
BLCA	chr12	6588300	Missense_Mutation	novel	Q1155E	0.26
BLCA	chr12	6581763	Missense_Mutation	novel	E1523Q	0.36
BLCA	chr12	6570637	3'UTR	novel		0.32
BLCA	chr12	6600390	Missense_Mutation	novel	E357K	0.19
BLCA	chr12	6573266	Missense_Mutation	novel	L1789V	0.43
BLCA	chr12	6598416	Missense_Mutation	novel	L498V	0.15
BLCA	chr12	6592007	Missense_Mutation	novel	R1000P	0.18
BLCA	chr12	6595363	Nonsense_Mutation	novel	E698*	0.39
BRCA	chr12	6581802	Missense_Mutation	NA	E1510Q	0.14
BRCA	chr12	6600550	Silent	novel	T349T	0.29
BRCA	chr12	6602094	Missense_Mutation	rs138116135	R102C	0.27
BRCA	chr12	6593114	Missense_Mutation	NA	R877W	0.3	ResIII
BRCA	chr12	6593169	Silent	NA	D858D	0.27
BRCA	chr12	6587931	Missense_Mutation	NA	R1162W	0.17
BRCA	chr12	6601385	Missense_Mutation	NA	A235P	0.69
BRCA	chr12	6602129	Missense_Mutation	NA	P90Q	0.35
BRCA	chr12	6593113	Missense_Mutation	NA	R877Q	0.44	ResIII
BRCA	chr12	6570986	Silent	NA	V1868V	0.28
BRCA	chr12	6591732	Missense_Mutation	novel	L1062V	0.05
BRCA	chr12	6599773	Splice_Region	novel	T494T	0.21
BRCA	chr12	6593472	Missense_Mutation	NA	E820K	0.18	ResIII
BRCA	chr12	6592041	Missense_Mutation	NA	I989F	0.37
BRCA	chr12	6606273	Splice_Site	NA	X34_splice	0.38
BRCA	chr12	6578894	Nonsense_Mutation	NA	E1645*	0.12
BRCA	chr12	6581141	Silent	NA	D1604D	0.13
BRCA	chr12	6602132	Missense_Mutation	novel	G89V	0.09
BRCA	chr12	6601053	Missense_Mutation	NA	G267V	0.36
BRCA	chr12	6570886	Missense_Mutation	novel	E1902K	0.08
BRCA	chr12	6600303	Missense_Mutation	NA	D386N	0.18
BRCA	chr12	6592417	Missense_Mutation	NA	R975H	0.08
BRCA	chr12	6600965	Missense_Mutation	novel	I296M	0.15
BRCA	chr12	6583251	Missense_Mutation	NA	G1336E	0.08
BRCA	chr12	6588373	Silent	novel	G1130G	0.31
BRCA	chr12	6570594	3'UTR	novel		0.27
BRCA	chr12	6583291	Missense_Mutation	NA	E1323Q	0.25
BRCA	chr12	6598072	Nonsense_Mutation	NA	R572*	0.16
BRCA	chr12	6593114	Missense_Mutation	NA	R877W	0.18	ResIII
BRCA	chr12	6570991	Missense_Mutation	NA	D1867N	0.19
BRCA	chr12	6591958	Missense_Mutation	NA	K1016N	0.38
BRCA	chr12	6587546	Silent	NA	K1239K	0.27
BRCA	chr12	6583317	Nonsense_Mutation	NA	W1314*	0.12
CESC	chr12	6570086	3'UTR	novel		0.2
CESC	chr12	6581125	Missense_Mutation	NA	E1610K	0.4
CESC	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.32
CESC	chr12	6583114	Splice_Site	NA	X1354_splice	0.61
CESC	chr12	6601696	Missense_Mutation	novel	E170G	0.64
CESC	chr12	6602477	Missense_Mutation	novel	E41K	0.3
CESC	chr12	6597989	Missense_Mutation	NA	K599N	0.27
CESC	chr12	6596082	Missense_Mutation	NA	D650N	0.53
CESC	chr12	6601662	Silent	NA	F181F	0.13
CESC	chr12	6582862	Missense_Mutation	novel	G1408S	0.65
CESC	chr12	6592745	Silent	rs748238713	L909L	0.31
CESC	chr12	6594623	Missense_Mutation	novel	E717K	0.4	ResIII
CESC	chr12	6601038	Missense_Mutation	novel	R272M	0.09
CESC	chr12	6594516	Missense_Mutation	NA	E752D	0.31	ResIII
CESC	chr12	6578633	Intron	novel		0.14
CESC	chr12	6577887	Silent	NA	Q1753Q	0.22
CESC	chr12	6602453	Missense_Mutation	rs779921079	P49A	0.18
CESC	chr12	6570093	3'UTR	novel		0.37
CESC	chr12	6599862	Missense_Mutation	NA	D465N	0.25
CESC	chr12	6581068	Missense_Mutation	rs760270237	E1629K	0.53
COAD	chr12	6578115	Silent	NA	N1714N	0.24
COAD	chr12	6597932	Missense_Mutation	novel	K618N	0.15
COAD	chr12	6582612	Splice_Region	rs773089748		0.13
COAD	chr12	6600309	Missense_Mutation	NA	L384M	0.41
COAD	chr12	6582872	Frame_Shift_Ins	NA	*L1404Ffs9**	0.42
COAD	chr12	6587885	Missense_Mutation	NA	R1177H	0.36
COAD	chr12	6596059	Silent	NA	E657E	0.32
COAD	chr12	6587834	Missense_Mutation	NA	L1194R	0.22
COAD	chr12	6588315	Missense_Mutation	NA	P1150S	0.18
COAD	chr12	6592505	Frame_Shift_Ins	NA	*L946Tfs3**	0.2
COAD	chr12	6592417	Missense_Mutation	NA	R975H	0.23
COAD	chr12	6583245	Missense_Mutation	NA	R1338I	0.21
COAD	chr12	6578406	Splice_Region	NA		0.33
COAD	chr12	6581787	Missense_Mutation	rs200017158	R1515C	0.37
COAD	chr12	6587875	Silent	NA	V1180V	0.43
COAD	chr12	6591526	Missense_Mutation	NA	E1094K	0.17
COAD	chr12	6581592	Intron	novel		0.34
COAD	chr12	6570513	3'UTR	novel		0.35
COAD	chr12	6583239	Missense_Mutation	NA	R1340H	0.31
COAD	chr12	6582870	Missense_Mutation	NA	A1405V	0.38
COAD	chr12	6581522	Intron	novel		0.12
COAD	chr12	6600216	Splice_Site	NA	X414_splice	0.19
COAD	chr12	6581787	Missense_Mutation	rs200017158	R1515C	0.08
COAD	chr12	6594536	Missense_Mutation	NA	D746N	0.41	ResIII
COAD	chr12	6591472	Missense_Mutation	NA	F1112L	0.28
COAD	chr12	6591493	Missense_Mutation	NA	R1105W	0.4
COAD	chr12	6583007	Intron	novel		0.13
COAD	chr12	6594458	Splice_Site	NA	X771_splice	0.05
COAD	chr12	6601389	Silent	rs533239676	A233A	0.24
COAD	chr12	6570945	Missense_Mutation	NA	A1882V	0.53
COAD	chr12	6581364	Frame_Shift_Del	NA	*N1569Ifs9**	0.44
COAD	chr12	6592503	Silent	rs772555151	L946L	0.28
COAD	chr12	6592417	Missense_Mutation	NA	R975H	0.37
COAD	chr12	6587889	Missense_Mutation	novel	T1176A	0.07
COAD	chr12	6591713	Missense_Mutation	NA	R1068H	0.09
COAD	chr12	6578710	Intron	novel		0.32
COAD	chr12	6583121	Splice_Region	NA		0.37
COAD	chr12	6591466	Missense_Mutation	NA	A1114T	0.32
COAD	chr12	6593587	Silent	NA	S781S	0.28
COAD	chr12	6600558	Nonsense_Mutation	NA	R347*	0.25
COAD	chr12	6582868	Missense_Mutation	NA	R1406G	0.22
COAD	chr12	6583007	Intron	novel		0.19
COAD	chr12	6600621	Missense_Mutation	NA	I326V	0.14
COAD	chr12	6588298	Splice_Region	novel	Q1155Q	0.05
COAD	chr12	6598071	Missense_Mutation	NA	R572Q	0.08
COAD	chr12	6582259	Missense_Mutation	NA	R1465W	0.33
COAD	chr12	6599826	Missense_Mutation	NA	N477D	0.28
COAD	chr12	6573233	Missense_Mutation	NA	R1800C	0.24
COAD	chr12	6583162	Intron	rs761755684		0.31
COAD	chr12	6593556	Missense_Mutation	NA	R792W	0.07	ResIII
COAD	chr12	6598386	Missense_Mutation	NA	W508R	0.32
COAD	chr12	6592417	Missense_Mutation	NA	R975H	0.34
COAD	chr12	6587441	Silent	rs746335183	N1274N	0.37
COAD	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.13
COAD	chr12	6581582	Intron	novel		0.27
COAD	chr12	6599843	Missense_Mutation	NA	Y471C	0.32
COAD	chr12	6582243	Missense_Mutation	NA	P1470L	0.21
COAD	chr12	6570955	Missense_Mutation	NA	P1879A	0.39
COAD	chr12	6598372	Silent	NA	Q512Q	0.25
DLBC	chr12	6593580	Missense_Mutation	novel	L784V	0.32	ResIII
DLBC	chr12	6601688	Nonsense_Mutation	NA	R173*	0.34
ESCA	chr12	6600557	Missense_Mutation	NA	R347Q	0.4
ESCA	chr12	6573229	Missense_Mutation	rs763955970	R1801Q	0.39
ESCA	chr12	6598222	Splice_Region	novel	Q562Q	0.14
ESCA	chr12	6591732	Missense_Mutation	novel	L1062I	0.08
ESCA	chr12	6570247	3'UTR	novel		0.27
ESCA	chr12	6570178	3'UTR	novel		0.19
GBM	chr12	6577902	Silent	novel	R1748R	0.26
GBM	chr12	6597969	Missense_Mutation	novel	A606E	0.04
GBM	chr12	6588350	Missense_Mutation	novel	A1138V	0.06
GBM	chr12	6596107	Missense_Mutation	NA	L641F	0.22
GBM	chr12	6599774	Missense_Mutation	rs375234607	T494M	0.09
GBM	chr12	6591523	Missense_Mutation	novel	R1095C	0.06
GBM	chr12	6600576	Missense_Mutation	novel	R341S	0.14
GBM	chr12	6592487	Missense_Mutation	novel	P952T	0.13
GBM	chr12	6591755	Missense_Mutation	novel	L1054P	0.11
GBM	chr12	6587755	Missense_Mutation	novel	K1220N	0.06
HNSC	chr12	6582176	Silent	novel	V1492V	0.12
HNSC	chr12	6591976	In_Frame_Del	novel	N1010del	0.05
HNSC	chr12	6600292	Silent	novel	P389P	0.13
HNSC	chr12	6600293	Missense_Mutation	novel	P389L	0.14
HNSC	chr12	6570867	Splice_Site	novel	X1907_splice	0.21
HNSC	chr12	6581732	Missense_Mutation	novel	P1533L	0.29
HNSC	chr12	6600374	Missense_Mutation	novel	V362E	0.11
HNSC	chr12	6581495	Intron	novel		0.08
HNSC	chr12	6597994	Nonsense_Mutation	NA	R598*	0.29
HNSC	chr12	6582932	Silent	novel	P1384P	0.07
HNSC	chr12	6597932	Frame_Shift_Del	novel	*K618Nfs5**	0.16
HNSC	chr12	6582280	Missense_Mutation	novel	A1458T	0.25
HNSC	chr12	6577909	Missense_Mutation	novel	Y1746C	0.22
HNSC	chr12	6583072	Missense_Mutation	novel	V1368M	0.1
HNSC	chr12	6583239	Missense_Mutation	NA	R1340H	0.27
KICH	chr12	6592474	Missense_Mutation	novel	R956L	0.44
KICH	chr12	6593564	Missense_Mutation	NA	N789S	0.29	ResIII
KIRC	chr12	6601676	Missense_Mutation	NA	N177D	0.36
KIRC	chr12	6578875	Missense_Mutation	NA	D1651A	0.17
KIRC	chr12	6601693	Missense_Mutation	NA	D171A	0.05
KIRC	chr12	6587916	Missense_Mutation	novel	K1167E	0.31
KIRC	chr12	6581661	Missense_Mutation	NA	V1557I	0.38
KIRC	chr12	6592468	Missense_Mutation	NA	L958H	0.31
KIRC	chr12	6581367	Missense_Mutation	NA	E1568A	0.28
KIRP	chr12	6598374	Nonsense_Mutation	NA	Q512*	0.15
KIRP	chr12	6602395	Missense_Mutation	NA	S68T	0.3
LAML	chr12	6592418	Missense_Mutation	NA	R975C	0.04
LAML	chr12	6582649	Missense_Mutation	novel	R1446G	0.15
LAML	chr12	6592417	Missense_Mutation	NA	R975H	0.26
LAML	chr12	6573123	Silent	novel	S1836S	0.03
LAML	chr12	6594520	Missense_Mutation	novel	D751V	0.08	ResIII
LGG	chr12	6592709	Missense_Mutation	NA	P921S	0.09
LGG	chr12	6593564	Missense_Mutation	NA	N789S	0.15	ResIII
LGG	chr12	6581131	Missense_Mutation	rs201992075	V1608I	0.41
LGG	chr12	6593521	Silent	rs112803905	V803V	0.42
LGG	chr12	6592468	Missense_Mutation	novel	L958R	0.05
LIHC	chr12	6594600	Frame_Shift_Del	novel	*D720Efs11**	0.41	ResIII
LIHC	chr12	6601697	Nonsense_Mutation	novel	E170*	0.35
LIHC	chr12	6591986	Missense_Mutation	NA	S1007F	0.49
LIHC	chr12	6581726	Missense_Mutation	NA	S1535L	0.21
LIHC	chr12	6573128	Silent	rs778830438	L1835L	0.15
LIHC	chr12	6592698	Missense_Mutation	novel	F924L	0.46
LIHC	chr12	6583338	Missense_Mutation	NA	E1307G	0.35
LIHC	chr12	6601399	Missense_Mutation	NA	A230V	0.51
LIHC	chr12	6583394	Intron	novel		0.17
LUAD	chr12	6600216	Splice_Site	NA	X414_splice	0.07
LUAD	chr12	6570950	Silent	novel	P1880P	0.16
LUAD	chr12	6593482	Missense_Mutation	NA	I816M	0.37	ResIII
LUAD	chr12	6587933	Missense_Mutation	NA	H1161R	0.3
LUAD	chr12	6606444	5'UTR	novel		0.21
LUAD	chr12	6598062	Missense_Mutation	novel	Q575L	0.06
LUAD	chr12	6597982	Missense_Mutation	NA	D602Y	0.41
LUAD	chr12	6601367	Missense_Mutation	novel	V241L	0.11
LUAD	chr12	6601451	Missense_Mutation	NA	S213G	0.12
LUAD	chr12	6598283	Missense_Mutation	NA	Q542P	0.36
LUAD	chr12	6598082	Missense_Mutation	novel	Q568H	0.68
LUAD	chr12	6599850	Missense_Mutation	novel	S469P	0.61
LUAD	chr12	6587869	Silent	novel	E1182E	0.21
LUAD	chr12	6598087	Missense_Mutation	novel	C567R	0.29
LUAD	chr12	6600363	Missense_Mutation	NA	E366Q	0.09
LUAD	chr12	6602081	Missense_Mutation	novel	E106G	0.3
LUAD	chr12	6593595	Silent	rs530395831	L779L	0.22
LUAD	chr12	6587758	Silent	novel	L1219L	0.22
LUAD	chr12	6593424	Missense_Mutation	novel	R836C	0.25	ResIII
LUAD	chr12	6581148	Missense_Mutation	rs771561972	S1602L	0.31
LUAD	chr12	6581149	Missense_Mutation	novel	S1602P	0.31
LUAD	chr12	6583473	Intron	novel		0.18
LUAD	chr12	6601328	Nonsense_Mutation	novel	E254*	0.29
LUSC	chr12	6587839	Missense_Mutation	novel	M1192I	0.16
LUSC	chr12	6583509	Intron	novel		0.65
LUSC	chr12	6594575	Missense_Mutation	NA	G733C	0.15	ResIII
LUSC	chr12	6606398	5'UTR	novel		0.31
LUSC	chr12	6570950	Frame_Shift_Ins	novel	*V1881Sfs11**	0.13
LUSC	chr12	6594492	Missense_Mutation	NA	Q760H	0.33	ResIII
LUSC	chr12	6578683	Intron	novel		0.43
LUSC	chr12	6587756	Missense_Mutation	NA	K1220R	0.43
LUSC	chr12	6587488	Missense_Mutation	NA	D1259H	0.05
LUSC	chr12	6581715	Missense_Mutation	NA	K1539E	0.25
LUSC	chr12	6593569	Silent	novel	I787I	0.06
LUSC	chr12	6583407	Intron	rs761797551		0.33
LUSC	chr12	6570594	3'UTR	novel		0.25
LUSC	chr12	6597965	Silent	NA	E607E	0.12
LUSC	chr12	6602063	Missense_Mutation	rs747906347	P112L	0.45
LUSC	chr12	6591487	Missense_Mutation	NA	E1107Q	0.1
LUSC	chr12	6602417	Missense_Mutation	novel	R61W	0.68
LUSC	chr12	6594510	Silent	novel	G754G	0.32
LUSC	chr12	6600243	Missense_Mutation	rs377488166	E406K	0.06
OV	chr12	6597939	Missense_Mutation	NA	G616E	0.13
OV	chr12	6582867	Missense_Mutation	NA	R1406L	0.19
OV	chr12	6582655	Missense_Mutation	novel	L1444I	0.44
OV	chr12	6598045	Missense_Mutation	novel	D581H	0.27
OV	chr12	6581687	Missense_Mutation	novel	D1548G	0.04
OV	chr12	6592017	Missense_Mutation	rs779545095	L997F	0.31
OV	chr12	6587559	Missense_Mutation	novel	G1235E	0.08
OV	chr12	6591792	Missense_Mutation	NA	G1042C	0.13
OV	chr12	6583675	Intron	novel		0.14
OV	chr12	6587497	Missense_Mutation	novel	R1256W	0.4
OV	chr12	6591764	Missense_Mutation	novel	K1051T	0.36
OV	chr12	6601007	Silent	NA	D282D	0.14
OV	chr12	6592013	Missense_Mutation	rs758014481	N998S	0.07
PAAD	chr12	6583379	Splice_Site	novel	X1294_splice	0.03
PAAD	chr12	6601289	Missense_Mutation	novel	G267S	0.03
PAAD	chr12	6578121	Nonsense_Mutation	novel	W1712*	0.21
PAAD	chr12	6581733	Missense_Mutation	novel	P1533T	0.15
PAAD	chr12	6591492	Missense_Mutation	NA	R1105Q	0.18
PAAD	chr12	6592751	Missense_Mutation	novel	N907H	0.04
PAAD	chr12	6598055	Silent	novel	K577K	0.2
PRAD	chr12	6593125	Missense_Mutation	NA	D873G	0.13	ResIII
PRAD	chr12	6592506	Frame_Shift_Del	novel	*K945Nfs28**	0.26
PRAD	chr12	6581576	Intron	novel		0.27
PRAD	chr12	6601962	Missense_Mutation	novel	K146E	0.24
PRAD	chr12	6601021	Missense_Mutation	novel	P278T	0.39
PRAD	chr12	6594499	Missense_Mutation	NA	T758I	0.3	ResIII
READ	chr12	6581683	Silent	novel	T1549T	0.26
READ	chr12	6592779	Silent	NA	K897K	0.25
READ	chr12	6598287	Missense_Mutation	NA	R541W	0.24
READ	chr12	6581535	Intron	novel		0.21
READ	chr12	6587447	Silent	NA	G1272G	0.58
READ	chr12	6598071	Missense_Mutation	NA	R572Q	0.17
READ	chr12	6583103	Silent	NA	D1357D	0.31
READ	chr12	6592031	Missense_Mutation	NA	R992Q	0.39
READ	chr12	6602392	Missense_Mutation	NA	K69T	0.32
SARC	chr12	6570570	3'UTR	novel		0.24
SARC	chr12	6583267	Nonsense_Mutation	novel	R1331*	0.55
SARC	chr12	6583268	Silent	rs769359634	A1330A	0.54
SARC	chr12	6606428	5'UTR	novel		0.63
SARC	chr12	6606429	5'UTR	novel		0.59
SKCM	chr12	6583121	Splice_Region	NA		0.38
SKCM	chr12	6583083	Missense_Mutation	NA	S1364F	0.19
SKCM	chr12	6591714	Missense_Mutation	NA	R1068C	0.28
SKCM	chr12	6581740	Missense_Mutation	novel	M1530I	0.54
SKCM	chr12	6598232	Missense_Mutation	NA	S559F	0.23
SKCM	chr12	6570592	3'UTR	novel		0.16
SKCM	chr12	6593191	Missense_Mutation	NA	S851F	0.11	ResIII
SKCM	chr12	6592462	Missense_Mutation	NA	A960V	0.19
SKCM	chr12	6582784	Intron	NA		0.3
SKCM	chr12	6593608	Silent	NA	S774S	0.32
SKCM	chr12	6583121	Splice_Region	NA		0.09
SKCM	chr12	6591784	Silent	NA	A1044A	0.25
SKCM	chr12	6600576	Missense_Mutation	novel	R341C	0.29
SKCM	chr12	6600577	Silent	novel	S340S	0.29
SKCM	chr12	6593099	Nonsense_Mutation	NA	Q882*	0.53	ResIII
SKCM	chr12	6582965	Intron	rs763407178		0.33
SKCM	chr12	6587899	Silent	NA	Y1172Y	0.51
SKCM	chr12	6581708	Missense_Mutation	NA	P1541L	0.55
SKCM	chr12	6591714	Missense_Mutation	NA	R1068C	0.18
SKCM	chr12	6583065	Missense_Mutation	NA	S1370L	0.46
SKCM	chr12	6596046	Nonsense_Mutation	NA	Q662*	0.11
SKCM	chr12	6581737	Silent	NA	S1531S	0.05
SKCM	chr12	6599833	Silent	novel	H474H	0.22
SKCM	chr12	6599835	Missense_Mutation	rs187920601	H474Y	0.43
SKCM	chr12	6591726	Missense_Mutation	novel	E1064K	0.45
SKCM	chr12	6592517	Nonsense_Mutation	novel	Q942*	0.23
SKCM	chr12	6592518	Silent	rs747303727	D941D	0.22
SKCM	chr12	6582943	Splice_Region	NA		0.39
SKCM	chr12	6583060	Missense_Mutation	novel	E1372K	0.25
SKCM	chr12	6594607	Missense_Mutation	NA	T722I	0.27	ResIII
SKCM	chr12	6582173	Silent	NA	L1493L	0.66
SKCM	chr12	6596104	Silent	NA	I642I	0.41
SKCM	chr12	6582894	Missense_Mutation	NA	D1397V	0.12
SKCM	chr12	6602008	Silent	rs368112823	S130S	0.42
SKCM	chr12	6602009	Missense_Mutation	rs754152386	S130F	0.39
SKCM	chr12	6600558	Nonsense_Mutation	NA	R347*	0.47
SKCM	chr12	6598421	Missense_Mutation	NA	P496L	0.07
SKCM	chr12	6578488	Silent	novel	P1680P	0.43
SKCM	chr12	6578489	Missense_Mutation	novel	P1680L	0.43
SKCM	chr12	6601711	Missense_Mutation	NA	H165L	0.27
SKCM	chr12	6596113	Silent	NA	H639H	0.2
SKCM	chr12	6582272	Silent	rs370369438	V1460V	0.29
SKCM	chr12	6570955	Missense_Mutation	novel	P1879S	0.53
SKCM	chr12	6573184	Missense_Mutation	NA	M1816T	0.25
SKCM	chr12	6593215	Missense_Mutation	NA	V843A	0.18	ResIII
SKCM	chr12	6591518	Silent	NA	I1096I	0.53
SKCM	chr12	6587795	Missense_Mutation	novel	T1207I	0.26
SKCM	chr12	6600941	Frame_Shift_Ins	novel	*R305Afs2**	0.44
STAD	chr12	6592549	Frame_Shift_Del	novel	*L931Wfs13**	0.28
STAD	chr12	6591472	Missense_Mutation	NA	F1112L	0.35
STAD	chr12	6599897	Missense_Mutation	novel	R453Q	0.26
STAD	chr12	6597955	Missense_Mutation	NA	R611C	0.33
STAD	chr12	6581323	Missense_Mutation	NA	V1583F	0.11
STAD	chr12	6596055	Missense_Mutation	NA	V659M	0.04
STAD	chr12	6594563	Silent	NA	L737L	0.21
STAD	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.21
STAD	chr12	6583173	Intron	rs761615091		0.25
STAD	chr12	6587885	Missense_Mutation	NA	R1177H	0.34
STAD	chr12	6587930	Missense_Mutation	NA	R1162Q	0.12
STAD	chr12	6600217	Splice_Region	rs761570351	C414C	0.2
STAD	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.21
STAD	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.19
STAD	chr12	6591492	Missense_Mutation	NA	R1105Q	0.35
STAD	chr12	6583253	Missense_Mutation	NA	K1335N	0.39
STAD	chr12	6598349	Missense_Mutation	NA	P520H	0.34
STAD	chr12	6578062	Missense_Mutation	NA	R1732L	0.24
STAD	chr12	6582868	Missense_Mutation	NA	R1406C	0.26
STAD	chr12	6606311	Silent	NA	D21D	0.2
STAD	chr12	6577792	Missense_Mutation	NA	R1785M	0.34
STAD	chr12	6599781	Frame_Shift_Del	novel	*R492Vfs7**	0.23
STAD	chr12	6583245	Missense_Mutation	NA	R1338I	0.34
STAD	chr12	6577904	Missense_Mutation	novel	R1748W	0.12
STAD	chr12	6606285	Frame_Shift_Del	novel	*P30Hfs172**	0.4
STAD	chr12	6583245	Missense_Mutation	NA	R1338I	0.19
STAD	chr12	6583047	Missense_Mutation	NA	D1376G	0.12
STAD	chr12	6587486	Silent	NA	D1259D	0.07
STAD	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.25
STAD	chr12	6592460	Missense_Mutation	NA	D961N	0.06
STAD	chr12	6578488	Frame_Shift_Del	novel	*K1681Rfs3**	0.18
STAD	chr12	6573233	Missense_Mutation	NA	R1800C	0.35
STAD	chr12	6582697	Nonsense_Mutation	NA	R1430*	0.26
STAD	chr12	6593493	Missense_Mutation	NA	R813C	0.16	ResIII
STAD	chr12	6578063	Missense_Mutation	rs767578728	R1732W	0.36
STAD	chr12	6587816	Missense_Mutation	NA	R1200Q	0.12
STAD	chr12	6570951	Frame_Shift_Del	novel	*P1880Sfs11**	0.24
STAD	chr12	6583240	Missense_Mutation	NA	R1340C	0.64
STAD	chr12	6577874	Missense_Mutation	NA	Y1758H	0.2
STAD	chr12	6583007	Intron	novel		0.31
STAD	chr12	6591927	Missense_Mutation	NA	V1027M	0.29
STAD	chr12	6593114	Missense_Mutation	NA	R877W	0.09	ResIII
STAD	chr12	6581702	Missense_Mutation	NA	P1543L	0.11
STAD	chr12	6592528	Missense_Mutation	novel	A938V	0.14
STAD	chr12	6592506	Frame_Shift_Del	novel	*K945Nfs28**	0.38
STAD	chr12	6595341	Missense_Mutation	NA	T705I	0.34
STAD	chr12	6578881	Missense_Mutation	NA	A1649V	0.24
STAD	chr12	6594588	Silent	rs368003608	P728P	0.26
STAD	chr12	6597955	Missense_Mutation	NA	R611C	0.06
STAD	chr12	6587476	Missense_Mutation	NA	D1263N	0.04
STAD	chr12	6591790	Silent	NA	G1042G	0.08
STAD	chr12	6592506	Frame_Shift_Del	novel	*K945Nfs28**	0.09
STAD	chr12	6583070	Silent	NA	V1368V	0.11
STAD	chr12	6593492	Missense_Mutation	NA	R813H	0.1	ResIII
STAD	chr12	6600584	Missense_Mutation	novel	R338H	0.32
STAD	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.17
UCEC	chr12	6593445	Missense_Mutation	novel	R829C	0.32	ResIII
UCEC	chr12	6593555	Missense_Mutation	NA	R792Q	0.35	ResIII
UCEC	chr12	6592815	Missense_Mutation	NA	F885L	0.32	ResIII
UCEC	chr12	6587931	Missense_Mutation	NA	R1162W	0.25
UCEC	chr12	6593555	Missense_Mutation	NA	R792Q	0.51	ResIII
UCEC	chr12	6588342	Missense_Mutation	NA	V1141L	0.47
UCEC	chr12	6591492	Missense_Mutation	novel	R1105P	0.45
UCEC	chr12	6591493	Missense_Mutation	NA	R1105W	0.41
UCEC	chr12	6583245	Missense_Mutation	NA	R1338I	0.31
UCEC	chr12	6597956	Silent	novel	E610E	0.08
UCEC	chr12	6570960	Missense_Mutation	NA	R1877Q	0.03
UCEC	chr12	6602416	Missense_Mutation	rs753831942	R61Q	0.25
UCEC	chr12	6591713	Missense_Mutation	NA	R1068H	0.39
UCEC	chr12	6593113	Missense_Mutation	NA	R877Q	0.24	ResIII
UCEC	chr12	6592053	Missense_Mutation	NA	Y985H	0.4
UCEC	chr12	6591518	Silent	NA	I1096I	0.34
UCEC	chr12	6600634	Silent	rs371206767	F321F	0.26
UCEC	chr12	6588341	Missense_Mutation	novel	V1141G	0.56
UCEC	chr12	6598286	Missense_Mutation	NA	R541Q	0.43
UCEC	chr12	6570255	3'UTR	novel		0.6
UCEC	chr12	6582830	Intron	NA		0.43
UCEC	chr12	6583524	Intron	NA		0.24
UCEC	chr12	6600557	Missense_Mutation	NA	R347Q	0.44
UCEC	chr12	6592417	Missense_Mutation	NA	R975H	0.55
UCEC	chr12	6583313	Missense_Mutation	novel	E1315D	0.49
UCEC	chr12	6600558	Nonsense_Mutation	NA	R347*	0.56
UCEC	chr12	6596097	Missense_Mutation	novel	R645W	0.41
UCEC	chr12	6601402	Missense_Mutation	novel	A229V	0.31
UCEC	chr12	6587930	Missense_Mutation	NA	R1162Q	0.22
UCEC	chr12	6592417	Missense_Mutation	NA	R975H	0.42
UCEC	chr12	6593113	Missense_Mutation	NA	R877Q	0.42	ResIII
UCEC	chr12	6592016	Missense_Mutation	NA	L997R	0.7
UCEC	chr12	6583007	Intron	novel		0.41
UCEC	chr12	6583245	Missense_Mutation	NA	R1338I	0.4
UCEC	chr12	6591526	Missense_Mutation	NA	E1094K	0.37
UCEC	chr12	6600276	Missense_Mutation	novel	V395I	0.36
UCEC	chr12	6583201	Nonsense_Mutation	novel	R1353*	0.26
UCEC	chr12	6592542	Missense_Mutation	novel	E933D	0.13
UCEC	chr12	6582931	Missense_Mutation	rs771875799	R1385C	0.44
UCEC	chr12	6591516	Missense_Mutation	novel	D1097G	0.48
UCEC	chr12	6592749	Missense_Mutation	novel	N907K	0.39
UCEC	chr12	6588383	Missense_Mutation	NA	R1127Q	0.36
UCEC	chr12	6577786	Missense_Mutation	NA	K1787R	0.44
UCEC	chr12	6581087	Missense_Mutation	NA	E1622D	0.18
UCEC	chr12	6587743	Missense_Mutation	NA	E1224D	0.24
UCEC	chr12	6601305	Missense_Mutation	NA	K261N	0.14
UCEC	chr12	6602447	Missense_Mutation	NA	L51I	0.12
UCEC	chr12	6587401	Missense_Mutation	novel	R1288W	0.43
UCEC	chr12	6591492	Missense_Mutation	NA	R1105Q	0.47
UCEC	chr12	6591714	Missense_Mutation	NA	R1068C	0.36
UCEC	chr12	6597946	Missense_Mutation	rs369228909	R614C	0.43
UCEC	chr12	6593492	Missense_Mutation	NA	R813H	0.2	ResIII
UCEC	chr12	6592417	Missense_Mutation	NA	R975H	0.41
UCEC	chr12	6591493	Missense_Mutation	NA	R1105W	0.27
UCEC	chr12	6587936	Missense_Mutation	novel	A1160G	0.44
UCEC	chr12	6591492	Missense_Mutation	NA	R1105Q	0.16
UCEC	chr12	6570158	3'UTR	novel		0.47
UCEC	chr12	6593556	Missense_Mutation	NA	R792W	0.38	ResIII
UCEC	chr12	6602498	Splice_Site	NA	X34_splice	0.23
UCEC	chr12	6573209	Missense_Mutation	NA	S1808P	0.11
UCEC	chr12	6598072	Nonsense_Mutation	NA	R572*	0.21
UCEC	chr12	6600940	Missense_Mutation	NA	R305C	0.35
UCEC	chr12	6602073	Missense_Mutation	NA	D109N	0.5
UCEC	chr12	6570347	3'UTR	novel		0.57
UCEC	chr12	6578045	Silent	novel	L1738L	0.4
UCEC	chr12	6591493	Missense_Mutation	NA	R1105W	0.42
UCEC	chr12	6583245	Missense_Mutation	NA	R1338I	0.35
UCEC	chr12	6600938	Silent	NA	R305R	0.25
UCEC	chr12	6591475	Missense_Mutation	NA	R1111C	0.11
UCEC	chr12	6578409	Nonsense_Mutation	novel	E1707*	0.22
UCEC	chr12	6582680	Silent	novel	P1435P	0.22
UCEC	chr12	6601464	Frame_Shift_Del	novel	*K208Nfs27**	0.37
UCEC	chr12	6588383	Missense_Mutation	NA	R1127Q	0.44
UCEC	chr12	6593191	Missense_Mutation	NA	S851F	0.44	ResIII
UCEC	chr12	6600290	Missense_Mutation	rs756628084	R390H	0.27
UCEC	chr12	6602389	Missense_Mutation	rs377735756	R70H	0.37
UCEC	chr12	6570427	3'UTR	novel		0.33
UCEC	chr12	6587931	Missense_Mutation	NA	R1162W	0.31
UCEC	chr12	6591513	Missense_Mutation	novel	G1098A	0.22
UCEC	chr12	6598071	Missense_Mutation	NA	R572Q	0.24
UCEC	chr12	6588374	Missense_Mutation	NA	G1130D	0.6
UCEC	chr12	6577791	Missense_Mutation	novel	R1785S	0.27
UCEC	chr12	6587874	Missense_Mutation	novel	E1181K	0.32
UCEC	chr12	6591493	Missense_Mutation	NA	R1105W	0.2
UCEC	chr12	6581064	Missense_Mutation	novel	P1630H	0.4
UCEC	chr12	6587882	Missense_Mutation	NA	A1178V	0.42
UCEC	chr12	6570537	3'UTR	novel		0.2
UCEC	chr12	6583082	Silent	novel	S1364S	0.34
UCEC	chr12	6588368	Missense_Mutation	novel	G1132V	0.52
UCEC	chr12	6597909	Missense_Mutation	NA	R626Q	0.52
UCEC	chr12	6601503	Missense_Mutation	novel	K195N	0.1
UCEC	chr12	6583245	Missense_Mutation	NA	R1338I	0.46
UCEC	chr12	6588311	Missense_Mutation	NA	H1151P	0.41
UCEC	chr12	6583245	Missense_Mutation	NA	R1338I	0.32
UCEC	chr12	6600340	Silent	rs779177743	C373C	0.45
UCEC	chr12	6591492	Missense_Mutation	novel	R1105L	0.23
UCEC	chr12	6587485	Missense_Mutation	NA	R1260C	0.81
UCEC	chr12	6597910	Nonsense_Mutation	novel	R626*	0.33
UCEC	chr12	6591493	Missense_Mutation	NA	R1105W	0.25
UCEC	chr12	6570346	3'UTR	novel		0.54
UCEC	chr12	6592417	Missense_Mutation	NA	R975H	0.49
UCEC	chr12	6587931	Missense_Mutation	NA	R1162W	0.3
UCEC	chr12	6587520	Missense_Mutation	NA	H1248P	0.4
UCEC	chr12	6570362	3'UTR	novel		0.32
UCEC	chr12	6582918	Missense_Mutation	NA	R1389H	0.33
UCEC	chr12	6587874	Missense_Mutation	novel	E1181K	0.35
UCEC	chr12	6597909	Missense_Mutation	NA	R626Q	0.21
UCEC	chr12	6593587	Silent	NA	S781S	0.27
UCEC	chr12	6594488	Missense_Mutation	novel	A762T	0.3	ResIII
UCEC	chr12	6598350	Missense_Mutation	novel	P520S	0.43
UCEC	chr12	6591493	Missense_Mutation	NA	R1105W	0.36
UCEC	chr12	6592031	Missense_Mutation	NA	R992Q	0.44
UCEC	chr12	6588353	Missense_Mutation	novel	T1137I	0.19
UCEC	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.29
UCEC	chr12	6592417	Missense_Mutation	NA	R975H	0.22
UCEC	chr12	6570302	3'UTR	novel		0.32
UCEC	chr12	6597990	Missense_Mutation	novel	K599T	0.28
UCEC	chr12	6592434	Missense_Mutation	NA	K969N	0.59
UCEC	chr12	6591513	Missense_Mutation	NA	G1098D	0.5
UCEC	chr12	6600608	Missense_Mutation	novel	S330Y	0.35
UCEC	chr12	6583302	Missense_Mutation	novel	R1319Q	0.48
UCEC	chr12	6592417	Missense_Mutation	NA	R975H	0.32
UCEC	chr12	6587931	Missense_Mutation	NA	R1162W	0.32
UCEC	chr12	6592423	Missense_Mutation	novel	I973S	0.38
UCEC	chr12	6583302	Missense_Mutation	novel	R1319Q	0.38
UCEC	chr12	6599952	Nonsense_Mutation	novel	E435*	0.36
UCEC	chr12	6600316	Missense_Mutation	novel	E381D	0.44
UCEC	chr12	6592505	Frame_Shift_Ins	NA	*L946Tfs3**	0.41
UCEC	chr12	6595402	Missense_Mutation	rs773573339	P685S	0.07
UCEC	chr12	6591493	Missense_Mutation	NA	R1105W	0.47
UCEC	chr12	6583007	Intron	novel		0.07
UCEC	chr12	6588356	Missense_Mutation	NA	A1136D	0.41
UCEC	chr12	6578066	Nonsense_Mutation	novel	R1731*	0.08
UCEC	chr12	6577864	Missense_Mutation	novel	L1761H	0.2
UCEC	chr12	6591714	Missense_Mutation	NA	R1068C	0.3
UCEC	chr12	6600385	Missense_Mutation	novel	E358D	0.36
UCEC	chr12	6592472	Missense_Mutation	NA	R957W	0.29
UCEC	chr12	6599831	Missense_Mutation	novel	C475Y	0.26
UCEC	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.3
UCEC	chr12	6583014	Intron	novel		0.2
UCEC	chr12	6582726	Missense_Mutation	novel	Q1420R	0.39
UCEC	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.46
UCEC	chr12	6573190	Missense_Mutation	NA	P1814H	0.25
UCEC	chr12	6583201	Nonsense_Mutation	novel	R1353*	0.05
UCEC	chr12	6598371	Missense_Mutation	novel	P513S	0.32
UCEC	chr12	6601417	Missense_Mutation	novel	A224V	0.18
UCEC	chr12	6601508	Missense_Mutation	NA	P194S	0.46
UCEC	chr12	6587940	Missense_Mutation	NA	R1159G	0.44
UCEC	chr12	6582648	Missense_Mutation	rs770630218	R1446K	0.25
UCEC	chr12	6587931	Missense_Mutation	NA	R1162W	0.31
UCEC	chr12	6601975	Missense_Mutation	NA	D141E	0.4
UCEC	chr12	6593125	Missense_Mutation	NA	D873G	0.31	ResIII
UCEC	chr12	6601023	Missense_Mutation	NA	S277N	0.4
UCEC	chr12	6587771	Missense_Mutation	NA	L1215R	0.3
UCEC	chr12	6583240	Missense_Mutation	NA	R1340C	0.37
UCEC	chr12	6583267	Nonsense_Mutation	novel	R1331*	0.36
UCEC	chr12	6570883	Missense_Mutation	novel	P1903S	0.21
UCEC	chr12	6578087	Missense_Mutation	novel	K1724Q	0.27
UCEC	chr12	6582696	Missense_Mutation	novel	R1430Q	0.35
UCEC	chr12	6583201	Nonsense_Mutation	novel	R1353*	0.23
UCEC	chr12	6587885	Missense_Mutation	NA	R1177H	0.19
UCEC	chr12	6591522	Missense_Mutation	novel	R1095H	0.54
UCEC	chr12	6592438	Missense_Mutation	novel	S968Y	0.22
UCEC	chr12	6593521	Silent	rs112803905	V803V	0.39
UCEC	chr12	6595394	Missense_Mutation	novel	K687N	0.17
UCEC	chr12	6597945	Missense_Mutation	novel	R614H	0.32
UCEC	chr12	6601468	Missense_Mutation	novel	A207V	0.17
UCEC	chr12	6593186	Nonsense_Mutation	novel	E853*	0.53	ResIII
UCEC	chr12	6593476	Missense_Mutation	novel	E818D	0.33	ResIII
UCEC	chr12	6577874	Missense_Mutation	NA	Y1758H	0.67
UCEC	chr12	6587940	Missense_Mutation	NA	R1159G	0.46
UCEC	chr12	6593438	Missense_Mutation	novel	G831D	0.29	ResIII
UCEC	chr12	6600340	Silent	rs779177743	C373C	0.33
UCEC	chr12	6606320	Missense_Mutation	novel	E18D	0.35
UCEC	chr12	6588378	Missense_Mutation	novel	G1129R	0.41
UCEC	chr12	6587460	Missense_Mutation	NA	T1268I	0.26
UCEC	chr12	6600545	Frame_Shift_Del	novel	*K351Rfs9**	0.29
UCEC	chr12	6602380	Frame_Shift_Del	NA	*K73Rfs129**	0.36
UCEC	chr12	6591743	Frame_Shift_Ins	novel	*M1058Nfs6**	0.22
UCEC	chr12	6593493	Missense_Mutation	NA	R813C	0.35	ResIII
UCEC	chr12	6588299	Missense_Mutation	novel	Q1155R	0.57
UCEC	chr12	6598346	Missense_Mutation	novel	R521Q	0.18
UCEC	chr12	6601017	Missense_Mutation	novel	R279H	0.45
UCEC	chr12	6570993	Missense_Mutation	novel	A1866D	0.44
UCEC	chr12	6583197	Splice_Site	novel	X1354_splice	0.38
UCEC	chr12	6591714	Missense_Mutation	NA	R1068C	0.4
UCS	chr12	6587403	Missense_Mutation	novel	V1287G	0.34
UCS	chr12	6577808	Missense_Mutation	novel	K1780E	0.98
UCS	chr12	6594550	Nonsense_Mutation	novel	W741*	0.43	ResIII
UCS	chr12	6583240	Missense_Mutation	NA	R1340C	0.38
UCS	chr12	6591493	Missense_Mutation	NA	R1105W	0.46
UCS	chr12	6591472	Missense_Mutation	NA	F1112L	0.48
UCS	chr12	6591767	Missense_Mutation	novel	G1050E	0.96
UCS	chr12	6591471	Missense_Mutation	novel	F1112S	0.73
UCS	chr12	6592029	Missense_Mutation	novel	N993H	0.36
UCS	chr12	6599972	Nonsense_Mutation	novel	S428*	0.4
UCS	chr12	6588392	Missense_Mutation	novel	L1124P	0.22
UCS	chr12	6601531	Splice_Site	novel	X186_splice	0.52

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.1042	0.11856
MESO	DEL	0.0805	0.17495
PAAD	DEL	0.125	0.0019175
TGCT	AMP	0.9467	3.5918e-21
THYM	AMP	0.0325	0.24554

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0028	Kaplan-Meier Survival Analysis
SARC	0.01	Kaplan-Meier Survival Analysis
ACC	0.038	Kaplan-Meier Survival Analysis
UCS	0.045	Kaplan-Meier Survival Analysis
HNSC	0.029	Kaplan-Meier Survival Analysis
SKCM	0.02	Kaplan-Meier Survival Analysis
KIRP	0.05	Kaplan-Meier Survival Analysis
CESC	0.018	Kaplan-Meier Survival Analysis
LAML	0.036	Kaplan-Meier Survival Analysis
KICH	0.01	Kaplan-Meier Survival Analysis
UCEC	0.0013	Kaplan-Meier Survival Analysis
LIHC	0.00097	Kaplan-Meier Survival Analysis
UVM	0.019	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000111642 (Gene tree)
Gene ID: 1108
Gene Symbol: CHD4
Alias: Mi-2b|Mi2-BETA
Full Name: chromodomain helicase DNA binding protein 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 44,443 bases
Position: chr12:6,570,082-6,614,524
Accession: 1919
RBP type: canonical RBP
Summary: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000494126	ResIII	PF04851.15	8.7e-10	1	1
ENSP00000494981	ResIII	PF04851.15	1.1e-09	1	1
ENSP00000494247	ResIII	PF04851.15	1.2e-09	1	1
ENSP00000493829	ResIII	PF04851.15	1.4e-09	1	1
ENSP00000349508	ResIII	PF04851.15	1.4e-09	1	1
ENSP00000496543	ResIII	PF04851.15	1.5e-09	1	1
ENSP00000494574	ResIII	PF04851.15	1.5e-09	1	1
ENSP00000493471	ResIII	PF04851.15	1.5e-09	1	1
ENSP00000494456	ResIII	PF04851.15	1.6e-09	1	1
ENSP00000493619	ResIII	PF04851.15	1.6e-09	1	1
ENSP00000496358	ResIII	PF04851.15	1.6e-09	1	1
ENSP00000440542	ResIII	PF04851.15	1.6e-09	1	1
ENSP00000496163	ResIII	PF04851.15	1.6e-09	1	1
ENSP00000440392	ResIII	PF04851.15	1.6e-09	1	1
ENSP00000496634	ResIII	PF04851.15	1.6e-09	1	1
ENSP00000496707	ResIII	PF04851.15	2.3e-09	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000647394	CHD4-251	1995	-	-	- (aa)	-	-
ENST00000642860	CHD4-215	1799	-	-	- (aa)	-	-
ENST00000646462	CHD4-244	2301	-	ENSP00000496291	605 (aa)	-	A0A2R8Y7I0
ENST00000645991	CHD4-238	1253	-	ENSP00000496457	73 (aa)	-	A0A2R8Y7X1
ENST00000644077	CHD4-222	1972	-	ENSP00000496233	560 (aa)	-	A0A2R8Y7M9
ENST00000647112	CHD4-249	1564	-	-	- (aa)	-	-
ENST00000642594	CHD4-211	6142	-	ENSP00000493619	1889 (aa)	-	A0A2R8Y425
ENST00000646145	CHD4-240	620	-	-	- (aa)	-	-
ENST00000647333	CHD4-250	753	-	-	- (aa)	-	-
ENST00000646268	CHD4-241	6236	-	ENSP00000495023	1377 (aa)	-	A0A2R8Y685
ENST00000644289	CHD4-225	5007	-	ENSP00000496707	1669 (aa)	-	A0A2R8Y8C1
ENST00000642637	CHD4-212	2501	-	ENSP00000495233	458 (aa)	-	A0A2R8YE38
ENST00000544484	CHD4-207	6555	-	ENSP00000440392	1937 (aa)	-	A0A0C4DGG9
ENST00000643538	CHD4-220	2533	-	ENSP00000494571	554 (aa)	-	A0A2R8Y5M9
ENST00000645645	CHD4-236	6297	XM_017018730	ENSP00000496543	1899 (aa)	XP_016874219	A0A2R8YFK9
ENST00000646787	CHD4-247	171	-	-	- (aa)	-	-
ENST00000430771	CHD4-202	527	-	-	- (aa)	-	-
ENST00000645265	CHD4-235	200	-	-	- (aa)	-	-
ENST00000646806	CHD4-248	6359	XM_017018732	ENSP00000494574	1892 (aa)	XP_016874221	A0A2R8Y5J0
ENST00000540960	CHD4-205	913	-	-	- (aa)	-	-
ENST00000545083	CHD4-208	511	-	-	- (aa)	-	-
ENST00000537634	CHD4-204	792	-	-	- (aa)	-	-
ENST00000642879	CHD4-216	6309	XM_024448804	ENSP00000494456	1920 (aa)	XP_024304572	A0A2R8Y521
ENST00000642810	CHD4-214	6630	-	ENSP00000495160	1425 (aa)	-	A0A2R8Y5Z7
ENST00000642686	CHD4-213	1204	-	-	- (aa)	-	-
ENST00000643367	CHD4-219	764	-	-	- (aa)	-	-
ENST00000646609	CHD4-246	854	-	-	- (aa)	-	-
ENST00000646608	CHD4-245	4988	-	ENSP00000493829	1554 (aa)	-	A0A2R8YDJ9
ENST00000644352	CHD4-226	4111	-	ENSP00000494981	1215 (aa)	-	A0A2R8YDW2
ENST00000645199	CHD4-234	1327	-	-	- (aa)	-	-
ENST00000643815	CHD4-221	4945	-	ENSP00000494247	1484 (aa)	-	A0A2R8YD40
ENST00000644356	CHD4-227	3075	-	-	- (aa)	-	-
ENST00000647535	CHD4-254	3099	-	-	- (aa)	-	-
ENST00000646070	CHD4-239	582	-	-	- (aa)	-	-
ENST00000645095	CHD4-232	6291	XM_006718958	ENSP00000496634	1940 (aa)	XP_006719021	Q14839
ENST00000545942	CHD4-210	1267	-	ENSP00000437506	354 (aa)	-	F5H6N4
ENST00000644652	CHD4-228	1616	-	ENSP00000495539	103 (aa)	-	A0A2R8Y6G9
ENST00000642893	CHD4-217	361	-	ENSP00000494441	16 (aa)	-	A0A2R8Y512
ENST00000645717	CHD4-237	311	-	-	- (aa)	-	-
ENST00000357008	CHD4-201	6438	XM_006718962	ENSP00000349508	1902 (aa)	XP_006719025	A0A2U3TZM0
ENST00000645005	CHD4-230	6175	XM_006718959	ENSP00000493471	1914 (aa)	XP_006719022	A0A2R8Y212
ENST00000644801	CHD4-229	5326	-	ENSP00000496660	1147 (aa)	-	A0A2R8Y8B3
ENST00000544040	CHD4-206	6582	XM_017018726	ENSP00000440542	1912 (aa)	XP_016874215	Q14839
ENST00000647483	CHD4-253	4145	-	ENSP00000494126	1262 (aa)	-	A0A2R8Y4X2
ENST00000643335	CHD4-218	6411	-	ENSP00000496358	1903 (aa)	-	A0A2R8YFD8
ENST00000645143	CHD4-233	612	-	ENSP00000495834	48 (aa)	-	A0A2R8Y795
ENST00000646360	CHD4-242	2867	-	-	- (aa)	-	-
ENST00000535717	CHD4-203	1405	-	-	- (aa)	-	-
ENST00000646366	CHD4-243	4622	-	-	- (aa)	-	-
ENST00000545584	CHD4-209	555	-	ENSP00000444614	125 (aa)	-	F5H596
ENST00000645022	CHD4-231	6673	XM_005253668	ENSP00000496163	1905 (aa)	XP_005253725	F5GWX5
ENST00000644137	CHD4-224	6499	-	ENSP00000495816	1645 (aa)	-	A0A2R8YER1
ENST00000647426	CHD4-252	168	-	-	- (aa)	-	-
ENST00000644132	CHD4-223	773	-	ENSP00000494498	51 (aa)	-	A0A2R8Y539

Gene Model

Click here to download ENSG00000111642's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05165	Human papillomavirus infection	KEGG
hsa05203	Viral carcinogenesis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000111642	Myopia, Degenerative	6E-6	23049088

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000111642	rs1057510	12	6574121	?	Myopia (pathological)	23049088	[NR]		EFO_0004207
ENSG00000111642	rs10849492	12	6611629	A	Heel bone mineral density	30598549	[0.0096-0.019] unit decrease	0.0142951	EFO_0009270
ENSG00000111642	rs7308584	12	6597578	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000111642	rs1639122	12	6601981	?	Red blood cell count	30595370			EFO_0004305
ENSG00000111642	rs1639122	12	6601981	?	Heel bone mineral density	30595370			EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000111642's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000111642	CHD4	67	37.062	ENSG00000173575	CHD2	87	68.367
ENSG00000111642	CHD4	52	36.256	ENSG00000127616	SMARCA4	91	39.437
ENSG00000111642	CHD4	99	75.184	ENSG00000170004	CHD3	99	64.038

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000111642	CHD4	99	82.594	ENSAPOG00000008935	chd4a	99	78.930	Acanthochromis_polyacanthus
ENSG00000111642	CHD4	99	74.315	ENSAPOG00000020502	-	93	71.104	Acanthochromis_polyacanthus
ENSG00000111642	CHD4	100	98.849	ENSAMEG00000014179	-	100	98.864	Ailuropoda_melanoleuca
ENSG00000111642	CHD4	99	79.487	ENSACIG00000012387	-	95	76.092	Amphilophus_citrinellus
ENSG00000111642	CHD4	99	81.547	ENSACIG00000019310	chd4a	90	92.825	Amphilophus_citrinellus
ENSG00000111642	CHD4	100	80.095	ENSAOCG00000016412	-	98	81.098	Amphiprion_ocellaris
ENSG00000111642	CHD4	99	80.725	ENSAOCG00000000507	-	98	76.157	Amphiprion_ocellaris
ENSG00000111642	CHD4	94	79.643	ENSAPEG00000001757	chd4a	99	77.347	Amphiprion_percula
ENSG00000111642	CHD4	99	80.469	ENSAPEG00000005957	-	98	75.501	Amphiprion_percula
ENSG00000111642	CHD4	99	74.485	ENSAPEG00000020306	-	89	83.019	Amphiprion_percula
ENSG00000111642	CHD4	99	75.422	ENSATEG00000000976	-	94	72.497	Anabas_testudineus
ENSG00000111642	CHD4	99	71.831	ENSATEG00000021141	-	96	75.949	Anabas_testudineus
ENSG00000111642	CHD4	91	86.675	ENSATEG00000016428	chd4a	95	86.192	Anabas_testudineus
ENSG00000111642	CHD4	99	92.626	ENSAPLG00000014146	-	100	88.468	Anas_platyrhynchos
ENSG00000111642	CHD4	99	90.583	ENSACAG00000006231	-	100	89.591	Anolis_carolinensis
ENSG00000111642	CHD4	100	100.000	ENSANAG00000035685	-	100	99.587	Aotus_nancymaae
ENSG00000111642	CHD4	99	80.272	ENSACLG00000015837	chd4a	96	77.740	Astatotilapia_calliptera
ENSG00000111642	CHD4	99	80.525	ENSACLG00000024468	-	95	78.451	Astatotilapia_calliptera
ENSG00000111642	CHD4	99	81.280	ENSAMXG00000010614	-	96	78.879	Astyanax_mexicanus
ENSG00000111642	CHD4	99	83.376	ENSAMXG00000019969	chd4a	98	79.848	Astyanax_mexicanus
ENSG00000111642	CHD4	100	98.745	ENSBTAG00000014734	CHD4	100	98.745	Bos_taurus
ENSG00000111642	CHD4	100	100.000	ENSCJAG00000008114	-	100	99.530	Callithrix_jacchus
ENSG00000111642	CHD4	100	99.435	ENSCAFG00000014929	CHD4	100	99.320	Canis_familiaris
ENSG00000111642	CHD4	100	99.313	ENSCAFG00020002892	-	100	99.313	Canis_lupus_dingo
ENSG00000111642	CHD4	100	98.635	ENSCHIG00000020766	-	100	98.635	Capra_hircus
ENSG00000111642	CHD4	99	98.584	ENSTSYG00000006069	-	98	98.739	Carlito_syrichta
ENSG00000111642	CHD4	99	98.787	ENSCPOG00000008504	-	99	98.989	Cavia_porcellus
ENSG00000111642	CHD4	100	100.000	ENSCCAG00000009686	-	100	99.582	Cebus_capucinus
ENSG00000111642	CHD4	100	100.000	ENSCATG00000006345	-	100	99.634	Cercocebus_atys
ENSG00000111642	CHD4	100	100.000	ENSCLAG00000012244	-	100	99.003	Chinchilla_lanigera
ENSG00000111642	CHD4	100	100.000	ENSCSAG00000010429	-	100	99.687	Chlorocebus_sabaeus
ENSG00000111642	CHD4	86	99.200	ENSCHOG00000000277	-	85	99.200	Choloepus_hoffmanni
ENSG00000111642	CHD4	99	92.362	ENSCPBG00000027716	-	96	90.838	Chrysemys_picta_bellii
ENSG00000111642	CHD4	99	61.107	ENSCSAVG00000004448	-	99	61.783	Ciona_savignyi
ENSG00000111642	CHD4	100	100.000	ENSCANG00000035317	-	100	99.103	Colobus_angolensis_palliatus
ENSG00000111642	CHD4	100	99.435	ENSCGRG00001020662	Chd4	100	98.022	Cricetulus_griseus_chok1gshd
ENSG00000111642	CHD4	99	99.433	ENSCGRG00000015920	Chd4	100	98.333	Cricetulus_griseus_crigri
ENSG00000111642	CHD4	99	74.880	ENSCSEG00000018096	-	92	70.290	Cynoglossus_semilaevis
ENSG00000111642	CHD4	99	81.625	ENSCSEG00000019943	-	98	77.412	Cynoglossus_semilaevis
ENSG00000111642	CHD4	92	88.235	ENSCSEG00000017173	chd4a	92	88.235	Cynoglossus_semilaevis
ENSG00000111642	CHD4	99	74.696	ENSCVAG00000016412	-	94	71.397	Cyprinodon_variegatus
ENSG00000111642	CHD4	91	93.151	ENSCVAG00000004940	chd4a	90	92.727	Cyprinodon_variegatus
ENSG00000111642	CHD4	99	81.178	ENSCVAG00000001128	-	96	78.551	Cyprinodon_variegatus
ENSG00000111642	CHD4	99	80.702	ENSDARG00000063535	chd4a	93	78.918	Danio_rerio
ENSG00000111642	CHD4	100	98.589	ENSDNOG00000001134	-	100	98.589	Dasypus_novemcinctus
ENSG00000111642	CHD4	99	97.243	ENSDORG00000001847	Chd4	98	97.119	Dipodomys_ordii
ENSG00000111642	CHD4	88	73.419	ENSEBUG00000012670	chd4a	92	75.847	Eptatretus_burgeri
ENSG00000111642	CHD4	100	99.435	ENSEASG00005016150	-	100	99.268	Equus_asinus_asinus
ENSG00000111642	CHD4	100	99.435	ENSECAG00000022005	CHD4	100	99.268	Equus_caballus
ENSG00000111642	CHD4	99	81.127	ENSELUG00000021276	chd4a	95	79.394	Esox_lucius
ENSG00000111642	CHD4	99	81.258	ENSELUG00000018086	-	97	79.540	Esox_lucius
ENSG00000111642	CHD4	100	99.435	ENSFCAG00000006877	-	100	99.320	Felis_catus
ENSG00000111642	CHD4	96	92.599	ENSFALG00000004785	-	97	94.208	Ficedula_albicollis
ENSG00000111642	CHD4	100	100.000	ENSFDAG00000020219	-	100	96.774	Fukomys_damarensis
ENSG00000111642	CHD4	87	90.067	ENSFHEG00000012736	-	97	79.191	Fundulus_heteroclitus
ENSG00000111642	CHD4	91	82.949	ENSFHEG00000003253	-	93	80.531	Fundulus_heteroclitus
ENSG00000111642	CHD4	99	79.520	ENSFHEG00000002013	chd4a	95	76.781	Fundulus_heteroclitus
ENSG00000111642	CHD4	82	97.561	ENSGMOG00000017923	-	73	97.959	Gadus_morhua
ENSG00000111642	CHD4	78	81.320	ENSGMOG00000015722	chd4a	99	81.273	Gadus_morhua
ENSG00000111642	CHD4	70	88.259	ENSGMOG00000003394	-	78	88.259	Gadus_morhua
ENSG00000111642	CHD4	90	90.522	ENSGALG00000013565	-	98	91.958	Gallus_gallus
ENSG00000111642	CHD4	99	78.832	ENSGAFG00000002778	chd4a	93	77.333	Gambusia_affinis
ENSG00000111642	CHD4	84	91.743	ENSGAFG00000014337	-	96	88.462	Gambusia_affinis
ENSG00000111642	CHD4	99	80.504	ENSGACG00000018705	chd4a	99	76.253	Gasterosteus_aculeatus
ENSG00000111642	CHD4	72	83.781	ENSGACG00000010099	-	99	77.019	Gasterosteus_aculeatus
ENSG00000111642	CHD4	99	92.234	ENSGAGG00000001416	-	97	90.365	Gopherus_agassizii
ENSG00000111642	CHD4	100	100.000	ENSGGOG00000001930	CHD4	100	99.948	Gorilla_gorilla
ENSG00000111642	CHD4	99	80.049	ENSHBUG00000019146	chd4a	95	75.251	Haplochromis_burtoni
ENSG00000111642	CHD4	99	80.589	ENSHBUG00000016000	-	95	78.451	Haplochromis_burtoni
ENSG00000111642	CHD4	100	100.000	ENSHGLG00000003093	-	100	98.845	Heterocephalus_glaber_female
ENSG00000111642	CHD4	100	100.000	ENSHGLG00100007450	-	100	98.797	Heterocephalus_glaber_male
ENSG00000111642	CHD4	96	79.225	ENSHCOG00000017525	-	98	74.941	Hippocampus_comes
ENSG00000111642	CHD4	99	64.286	ENSHCOG00000014308	-	88	74.038	Hippocampus_comes
ENSG00000111642	CHD4	99	83.398	ENSIPUG00000005694	chd4	96	80.666	Ictalurus_punctatus
ENSG00000111642	CHD4	100	98.870	ENSSTOG00000007601	-	99	98.951	Ictidomys_tridecemlineatus
ENSG00000111642	CHD4	100	98.065	ENSJJAG00000012394	Chd4	100	98.105	Jaculus_jaculus
ENSG00000111642	CHD4	99	80.215	ENSKMAG00000007932	-	92	77.372	Kryptolebias_marmoratus
ENSG00000111642	CHD4	99	80.245	ENSKMAG00000019286	chd4a	95	77.697	Kryptolebias_marmoratus
ENSG00000111642	CHD4	99	74.441	ENSKMAG00000017827	-	90	79.736	Kryptolebias_marmoratus
ENSG00000111642	CHD4	99	79.750	ENSLBEG00000012434	CHD4	92	75.484	Labrus_bergylta
ENSG00000111642	CHD4	99	74.877	ENSLBEG00000026652	-	95	73.635	Labrus_bergylta
ENSG00000111642	CHD4	99	78.701	ENSLOCG00000007438	chd4a	95	76.590	Lepisosteus_oculatus
ENSG00000111642	CHD4	100	99.435	ENSLAFG00000022842	-	100	95.766	Loxodonta_africana
ENSG00000111642	CHD4	100	100.000	ENSMFAG00000003188	-	100	99.738	Macaca_fascicularis
ENSG00000111642	CHD4	100	100.000	ENSMMUG00000018685	-	100	99.742	Macaca_mulatta
ENSG00000111642	CHD4	100	100.000	ENSMNEG00000044776	-	100	97.883	Macaca_nemestrina
ENSG00000111642	CHD4	100	100.000	ENSMLEG00000024661	-	100	97.780	Mandrillus_leucophaeus
ENSG00000111642	CHD4	99	80.038	ENSMAMG00000002584	-	89	85.714	Mastacembelus_armatus
ENSG00000111642	CHD4	99	74.326	ENSMAMG00000002137	-	91	70.296	Mastacembelus_armatus
ENSG00000111642	CHD4	100	81.923	ENSMAMG00000018954	chd4a	96	78.080	Mastacembelus_armatus
ENSG00000111642	CHD4	99	81.159	ENSMZEG00005001706	chd4a	96	77.728	Maylandia_zebra
ENSG00000111642	CHD4	99	80.525	ENSMZEG00005017761	-	95	78.395	Maylandia_zebra
ENSG00000111642	CHD4	99	92.816	ENSMGAG00000014084	-	100	90.716	Meleagris_gallopavo
ENSG00000111642	CHD4	100	99.435	ENSMICG00000006588	-	100	99.425	Microcebus_murinus
ENSG00000111642	CHD4	100	99.200	ENSMOCG00000020624	Chd4	100	98.381	Microtus_ochrogaster
ENSG00000111642	CHD4	99	79.833	ENSMMOG00000015971	-	95	76.802	Mola_mola
ENSG00000111642	CHD4	99	81.981	ENSMMOG00000000073	chd4a	99	76.710	Mola_mola
ENSG00000111642	CHD4	99	64.337	ENSMMOG00000013429	-	86	75.653	Mola_mola
ENSG00000111642	CHD4	99	95.521	ENSMODG00000018094	-	100	96.993	Monodelphis_domestica
ENSG00000111642	CHD4	99	80.505	ENSMALG00000005766	chd4a	96	76.602	Monopterus_albus
ENSG00000111642	CHD4	100	80.228	ENSMALG00000022494	-	95	77.001	Monopterus_albus
ENSG00000111642	CHD4	100	98.588	ENSMUSG00000063870	Chd4	100	98.172	Mus_musculus
ENSG00000111642	CHD4	100	98.588	MGP_SPRETEiJ_G0029911	Chd4	100	98.174	Mus_spretus
ENSG00000111642	CHD4	100	99.268	ENSMPUG00000016859	-	100	99.268	Mustela_putorius_furo
ENSG00000111642	CHD4	100	98.902	ENSMLUG00000014343	-	99	98.902	Myotis_lucifugus
ENSG00000111642	CHD4	100	98.023	ENSNGAG00000016920	Chd4	100	97.019	Nannospalax_galili
ENSG00000111642	CHD4	99	80.397	ENSNBRG00000021576	-	95	78.395	Neolamprologus_brichardi
ENSG00000111642	CHD4	100	98.195	ENSNLEG00000004330	-	96	98.700	Nomascus_leucogenys
ENSG00000111642	CHD4	94	99.200	ENSMEUG00000015294	-	84	99.200	Notamacropus_eugenii
ENSG00000111642	CHD4	100	97.740	ENSOPRG00000003477	-	84	99.531	Ochotona_princeps
ENSG00000111642	CHD4	100	100.000	ENSODEG00000003114	-	99	98.896	Octodon_degus
ENSG00000111642	CHD4	99	81.749	ENSONIG00000006992	chd4a	93	79.922	Oreochromis_niloticus
ENSG00000111642	CHD4	99	80.400	ENSONIG00000012953	-	94	78.675	Oreochromis_niloticus
ENSG00000111642	CHD4	100	98.039	ENSOCUG00000008215	-	99	96.653	Oryctolagus_cuniculus
ENSG00000111642	CHD4	99	79.863	ENSORLG00000006310	chd4a	93	77.948	Oryzias_latipes
ENSG00000111642	CHD4	99	81.240	ENSORLG00000012477	-	96	77.273	Oryzias_latipes
ENSG00000111642	CHD4	99	74.830	ENSORLG00000017190	-	90	82.273	Oryzias_latipes
ENSG00000111642	CHD4	99	79.963	ENSORLG00020006529	chd4a	93	77.948	Oryzias_latipes_hni
ENSG00000111642	CHD4	99	80.252	ENSORLG00020004891	-	92	76.721	Oryzias_latipes_hni
ENSG00000111642	CHD4	99	63.864	ENSORLG00020011739	-	87	75.335	Oryzias_latipes_hni
ENSG00000111642	CHD4	100	81.818	ENSORLG00015019674	chd4a	96	78.283	Oryzias_latipes_hsok
ENSG00000111642	CHD4	99	81.549	ENSORLG00015010692	-	96	78.400	Oryzias_latipes_hsok
ENSG00000111642	CHD4	91	90.747	ENSOMEG00000016394	chd4a	90	92.377	Oryzias_melastigma
ENSG00000111642	CHD4	99	70.907	ENSOMEG00000014929	-	93	69.052	Oryzias_melastigma
ENSG00000111642	CHD4	99	81.030	ENSOMEG00000013408	-	91	77.465	Oryzias_melastigma
ENSG00000111642	CHD4	100	99.153	ENSOGAG00000010031	-	100	99.124	Otolemur_garnettii
ENSG00000111642	CHD4	99	98.585	ENSOARG00000007398	-	100	98.618	Ovis_aries
ENSG00000111642	CHD4	100	100.000	ENSPPAG00000029007	-	100	99.948	Pan_paniscus
ENSG00000111642	CHD4	100	99.435	ENSPPRG00000001388	-	100	99.226	Panthera_pardus
ENSG00000111642	CHD4	100	99.268	ENSPTIG00000010979	-	100	99.268	Panthera_tigris_altaica
ENSG00000111642	CHD4	100	100.000	ENSPTRG00000004580	CHD4	100	99.948	Pan_troglodytes
ENSG00000111642	CHD4	100	100.000	ENSPANG00000025409	-	100	99.690	Papio_anubis
ENSG00000111642	CHD4	99	84.228	ENSPKIG00000008268	chd4a	93	81.232	Paramormyrops_kingsleyae
ENSG00000111642	CHD4	98	74.079	ENSPKIG00000012023	-	95	71.896	Paramormyrops_kingsleyae
ENSG00000111642	CHD4	99	90.950	ENSPSIG00000015546	-	99	88.711	Pelodiscus_sinensis
ENSG00000111642	CHD4	95	74.062	ENSPMGG00000007681	-	99	70.412	Periophthalmus_magnuspinnatus
ENSG00000111642	CHD4	99	81.706	ENSPMGG00000022981	chd4a	97	79.403	Periophthalmus_magnuspinnatus
ENSG00000111642	CHD4	100	98.870	ENSPEMG00000010290	Chd4	100	96.552	Peromyscus_maniculatus_bairdii
ENSG00000111642	CHD4	99	97.540	ENSPCIG00000001846	-	100	97.718	Phascolarctos_cinereus
ENSG00000111642	CHD4	99	80.299	ENSPFOG00000009089	chd4a	93	78.758	Poecilia_formosa
ENSG00000111642	CHD4	100	65.630	ENSPFOG00000016981	-	92	70.933	Poecilia_formosa
ENSG00000111642	CHD4	99	79.600	ENSPFOG00000013889	-	96	76.438	Poecilia_formosa
ENSG00000111642	CHD4	99	79.793	ENSPLAG00000012712	chd4a	93	77.627	Poecilia_latipinna
ENSG00000111642	CHD4	99	80.013	ENSPLAG00000004006	-	91	79.704	Poecilia_latipinna
ENSG00000111642	CHD4	99	75.161	ENSPMEG00000015657	-	94	71.380	Poecilia_mexicana
ENSG00000111642	CHD4	99	80.556	ENSPMEG00000009633	chd4a	94	78.346	Poecilia_mexicana
ENSG00000111642	CHD4	99	80.475	ENSPMEG00000006064	-	96	75.975	Poecilia_mexicana
ENSG00000111642	CHD4	95	73.778	ENSPREG00000014285	-	88	82.249	Poecilia_reticulata
ENSG00000111642	CHD4	99	79.687	ENSPREG00000011359	-	92	76.426	Poecilia_reticulata
ENSG00000111642	CHD4	89	94.500	ENSPREG00000001202	chd4a	90	94.500	Poecilia_reticulata
ENSG00000111642	CHD4	99	97.968	ENSPPYG00000004192	-	100	97.968	Pongo_abelii
ENSG00000111642	CHD4	98	95.826	ENSPCAG00000007120	-	85	100.000	Procavia_capensis
ENSG00000111642	CHD4	100	99.435	ENSPCOG00000018635	-	100	99.263	Propithecus_coquereli
ENSG00000111642	CHD4	98	98.951	ENSPVAG00000012574	-	100	98.951	Pteropus_vampyrus
ENSG00000111642	CHD4	99	79.648	ENSPNYG00000023020	-	92	76.978	Pundamilia_nyererei
ENSG00000111642	CHD4	99	81.918	ENSPNYG00000002663	chd4a	94	79.337	Pundamilia_nyererei
ENSG00000111642	CHD4	100	81.923	ENSPNAG00000011129	-	94	79.066	Pygocentrus_nattereri
ENSG00000111642	CHD4	92	93.254	ENSPNAG00000009629	chd4a	92	87.137	Pygocentrus_nattereri
ENSG00000111642	CHD4	100	97.657	ENSRNOG00000018309	Chd4	100	97.657	Rattus_norvegicus
ENSG00000111642	CHD4	100	100.000	ENSRBIG00000041491	-	100	99.676	Rhinopithecus_bieti
ENSG00000111642	CHD4	100	100.000	ENSRROG00000042446	-	100	99.686	Rhinopithecus_roxellana
ENSG00000111642	CHD4	100	100.000	ENSSBOG00000020782	-	100	98.425	Saimiri_boliviensis_boliviensis
ENSG00000111642	CHD4	100	90.459	ENSSHAG00000015079	-	95	94.312	Sarcophilus_harrisii
ENSG00000111642	CHD4	99	83.622	ENSSFOG00015002908	chd4	96	80.588	Scleropages_formosus
ENSG00000111642	CHD4	96	95.673	ENSSMAG00000012594	chd4a	95	79.227	Scophthalmus_maximus
ENSG00000111642	CHD4	99	80.525	ENSSMAG00000010969	-	95	75.403	Scophthalmus_maximus
ENSG00000111642	CHD4	99	72.684	ENSSMAG00000017926	-	92	69.295	Scophthalmus_maximus
ENSG00000111642	CHD4	99	81.031	ENSSDUG00000012051	-	93	76.944	Seriola_dumerili
ENSG00000111642	CHD4	99	81.777	ENSSDUG00000002891	chd4a	97	79.134	Seriola_dumerili
ENSG00000111642	CHD4	99	74.537	ENSSLDG00000019750	-	95	70.773	Seriola_lalandi_dorsalis
ENSG00000111642	CHD4	99	79.433	ENSSLDG00000018645	chd4a	98	77.288	Seriola_lalandi_dorsalis
ENSG00000111642	CHD4	92	89.810	ENSSLDG00000023821	-	87	86.333	Seriola_lalandi_dorsalis
ENSG00000111642	CHD4	92	88.785	ENSSARG00000012988	-	72	100.000	Sorex_araneus
ENSG00000111642	CHD4	99	89.350	ENSSPUG00000015131	-	100	89.902	Sphenodon_punctatus
ENSG00000111642	CHD4	99	81.496	ENSSPAG00000013983	chd4a	99	78.571	Stegastes_partitus
ENSG00000111642	CHD4	99	74.887	ENSSPAG00000018749	-	94	71.516	Stegastes_partitus
ENSG00000111642	CHD4	100	99.200	ENSSSCG00000000697	-	100	99.003	Sus_scrofa
ENSG00000111642	CHD4	99	91.892	ENSTGUG00000013329	-	100	90.016	Taeniopygia_guttata
ENSG00000111642	CHD4	99	81.536	ENSTRUG00000007202	-	99	76.503	Takifugu_rubripes
ENSG00000111642	CHD4	99	74.693	ENSTRUG00000007623	-	88	77.974	Takifugu_rubripes
ENSG00000111642	CHD4	99	81.355	ENSTNIG00000008031	-	98	76.756	Tetraodon_nigroviridis
ENSG00000111642	CHD4	99	70.793	ENSTNIG00000004095	-	95	75.630	Tetraodon_nigroviridis
ENSG00000111642	CHD4	98	96.370	ENSTBEG00000011379	-	90	100.000	Tupaia_belangeri
ENSG00000111642	CHD4	98	97.448	ENSTTRG00000016102	-	97	98.305	Tursiops_truncatus
ENSG00000111642	CHD4	100	99.718	ENSUAMG00000016452	-	100	99.226	Ursus_americanus
ENSG00000111642	CHD4	100	98.039	ENSUMAG00000005336	-	98	99.149	Ursus_maritimus
ENSG00000111642	CHD4	100	99.435	ENSVVUG00000011414	-	100	99.320	Vulpes_vulpes
ENSG00000111642	CHD4	99	85.749	ENSXETG00000026410	chd4	100	92.865	Xenopus_tropicalis
ENSG00000111642	CHD4	87	82.888	ENSXETG00000018961	-	99	82.029	Xenopus_tropicalis
ENSG00000111642	CHD4	99	81.118	ENSXCOG00000019269	-	96	76.533	Xiphophorus_couchianus
ENSG00000111642	CHD4	89	83.074	ENSXMAG00000001037	chd4a	88	83.746	Xiphophorus_maculatus
ENSG00000111642	CHD4	99	75.167	ENSXMAG00000014686	-	93	82.727	Xiphophorus_maculatus
ENSG00000111642	CHD4	99	80.989	ENSXMAG00000011263	-	96	76.408	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000790	nuclear chromatin	16217013.	HDA	Component
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	16217013.	HDA	Function
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	16217013.	HDA	Function
GO:0001103	RNA polymerase II repressing transcription factor binding	22926524.	IPI	Function
GO:0003677	DNA binding	9326634.	TAS	Function
GO:0004003	ATP-dependent DNA helicase activity	9326634.	TAS	Function
GO:0005515	protein binding	9804427.10220385.17314511.19644445.20693977.21258344.21555454.22720776.23752268.25150861.26859351.28977666.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	22720776.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	17626165.	IDA	Component
GO:0005813	centrosome	17626165.	IDA	Component
GO:0006357	regulation of transcription by RNA polymerase II	9326634.	TAS	Process
GO:0008270	zinc ion binding	7560064.	TAS	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0016581	NuRD complex	19644445.	IDA	Component
GO:0031492	nucleosomal DNA binding	16217013.	HDA	Function
GO:0032508	DNA duplex unwinding	-	IEA	Process
GO:0032991	protein-containing complex	16217013.	HDA	Component
GO:0042826	histone deacetylase binding	27616479.	IPI	Function
GO:0043044	ATP-dependent chromatin remodeling	16217013.	HDA	Process
GO:1901796	regulation of signal transduction by p53 class mediator	-	TAS	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.