EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23408445	Genetic variants of AICDA/CASP14 associated with childhood brain tumor.	Genet Mol Res	2013 Jun 20	Jeon S	doi: 10.4238/2013.January.30.1.
21290192	Aberrant expression and mutation-inducing activity of AID in human lung cancer.	Ann Surg Oncol	2011 Jul	Shinmura K	doi: 10.1245/s10434-011-1568-8
23198547	[Chronic inflammation and gastric cancer development].	Nihon Rinsho	2012 Oct	Chiba T	-
24351917	Expression of activation-induced cytidine deaminase in oral epithelial dysplasia and oral squamous cell carcinoma.	J Oral Sci	2013	Miyazaki Y	-
21109971	Ectopic expression of activation-induced cytidine deaminase caused by epigenetics modification.	Oncol Rep	2011 Jan	Tatemichi M	-
20927319	Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy.	Neoplasia	2010 Oct	Fujita H	-
20878190	Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers.	J Gastroenterol	2011 Jan	Endo Y	doi: 10.1007/s00535-010-0326-1
25849121	AID expression increased by TNF-α is associated with class switch recombination of Igα gene in cancers.	Cell Mol Immunol	2016 Jul	Duan Z	doi: 10.1038/cmi.2015.26

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr12	8606928	Silent	rs777729620	Y31Y	0.5
BLCA	chr12	8604873	Silent	novel	F159F	0.59
BLCA	chr12	8604839	Missense_Mutation	novel	R171S	0.33
BLCA	chr12	8606928	Silent	rs777729620	Y31Y	0.35
BLCA	chr12	8605405	Silent	NA	T79T	0.28
BLCA	chr12	8604839	Missense_Mutation	novel	R171S	0.17
BRCA	chr12	8606965	Missense_Mutation	novel	R19H	0.09
BRCA	chr12	8606876	Missense_Mutation	novel	L49I	0.28
BRCA	chr12	8604189	3'UTR	novel		0.42
CESC	chr12	8607013	Splice_Site	NA	X3_splice	0.12
CESC	chr12	8603799	3'UTR	novel		0.3
COAD	chr12	8605411	Silent	rs754343795	R77R	0.41
COAD	chr12	8604812	Missense_Mutation	NA	L180I	0.34
COAD	chr12	8605429	Missense_Mutation	NA	D71E	0.34
COAD	chr12	8604192	3'UTR	novel		0.1
COAD	chr12	8606966	Missense_Mutation	NA	R19C	0.29
COAD	chr12	8605444	Silent	NA	S66S	0.08
COAD	chr12	8605248	Missense_Mutation	NA	A132T	0.24	APOBEC_N
COAD	chr12	8612815	5'UTR	novel		0.45
COAD	chr12	8604209	3'UTR	novel		0.32
COAD	chr12	8606915	Missense_Mutation	rs200228627	R36C	0.09
COAD	chr12	8605483	Splice_Region	NA	N53N	0.28
COAD	chr12	8605281	Missense_Mutation	NA	A121T	0.38	APOBEC_N
COAD	chr12	8604209	3'UTR	novel		0.33
COAD	chr12	8604880	Missense_Mutation	NA	R157I	0.39
COAD	chr12	8604821	Missense_Mutation	novel	R177W	0.04
ESCA	chr12	8612792	5'UTR	novel		0.2
ESCA	chr12	8604307	Missense_Mutation	novel	A192T	0.19
ESCA	chr12	8605246	Silent	rs763771833	A132A	0.37
ESCA	chr12	8606991	Missense_Mutation	novel	K10N	0.11
GBM	chr12	8605410	Missense_Mutation	NA	V78I	0.32
GBM	chr12	8606914	Missense_Mutation	rs759799595	R36H	0.86
GBM	chr12	8605412	Missense_Mutation	NA	R77H	0.4
GBM	chr12	8605411	Silent	rs754343795	R77R	0.35
GBM	chr12	8605377	Missense_Mutation	rs772899277	D89N	0.41
GBM	chr12	8612821	5'UTR	novel		0.12
HNSC	chr12	8605445	Missense_Mutation	NA	S66L	0.12
HNSC	chr12	8605254	Missense_Mutation	novel	H130Y	0.48	APOBEC_N
KICH	chr12	8604817	Missense_Mutation	novel	R178H	0.32
KICH	chr12	8606906	Missense_Mutation	novel	A39T	0.16
KIRC	chr12	8605421	Missense_Mutation	NA	R74H	0.43
LGG	chr12	8605347	Nonsense_Mutation	rs757606065	R99*	0.2
LIHC	chr12	8606918	Missense_Mutation	NA	R35W	0.34
LIHC	chr12	8604109	3'UTR	novel		0.5
LIHC	chr12	8606935	Missense_Mutation	NA	L29R	0.38
LUAD	chr12	8606947	Missense_Mutation	novel	R25L	0.22
LUAD	chr12	8604307	Missense_Mutation	novel	A192S	0.45
LUAD	chr12	8604249	3'UTR	novel		0.37
LUAD	chr12	8605402	Missense_Mutation	NA	W80C	0.11
LUAD	chr12	8604818	Missense_Mutation	NA	R178C	0.46
LUSC	chr12	8605447	Silent	rs371803016	I65I	0.13
LUSC	chr12	8605342	Silent	novel	G100G	0.25
LUSC	chr12	8605413	Missense_Mutation	novel	R77G	0.28
LUSC	chr12	8605251	Missense_Mutation	NA	R131G	0.15	APOBEC_N
LUSC	chr12	8605253	Missense_Mutation	novel	H130P	0.21	APOBEC_N
LUSC	chr12	8604261	3'UTR	novel		0.21
LUSC	chr12	8605251	Missense_Mutation	NA	R131G	0.21	APOBEC_N
LUSC	chr12	8612826	5'UTR	novel		0.2
LUSC	chr12	8604247	3'UTR	novel		0.39
LUSC	chr12	8605423	Silent	novel	G73G	0.41
OV	chr12	8612785	5'UTR	novel		0.35
PRAD	chr12	8605444	Silent	NA	S66S	0.08
PRAD	chr12	8605311	Missense_Mutation	NA	A111T	0.42	APOBEC_N
READ	chr12	8604914	Missense_Mutation	novel	Y146H	0.36
READ	chr12	8605310	Missense_Mutation	NA	A111V	0.17	APOBEC_N
SARC	chr12	8604132	3'UTR	novel		0.19
SKCM	chr12	8605342	Silent	NA	G100G	0.66
SKCM	chr12	8605342	Silent	NA	G100G	0.49
SKCM	chr12	8604884	Missense_Mutation	rs775814283	E156K	0.6
SKCM	chr12	8604812	Missense_Mutation	NA	L180F	0.45
SKCM	chr12	8605456	Silent	NA	L62L	0.17
SKCM	chr12	8605273	Silent	rs199980715	P123P	0.58
SKCM	chr12	8605445	Missense_Mutation	NA	S66L	0.24
SKCM	chr12	8604839	Missense_Mutation	rs373061990	R171C	0.31
SKCM	chr12	8606994	Silent	novel	R9R	0.48
SKCM	chr12	8604884	Missense_Mutation	rs775814283	E156K	0.14
SKCM	chr12	8605456	Silent	NA	L62L	0.14
SKCM	chr12	8604844	Missense_Mutation	NA	S169L	0.4
SKCM	chr12	8605270	Silent	novel	E124E	0.5
STAD	chr12	8605263	Missense_Mutation	rs141451637	R127W	0.27	APOBEC_N
STAD	chr12	8605410	Missense_Mutation	NA	V78I	0.35
STAD	chr12	8607013	Splice_Site	NA	X3_splice	0.2
THCA	chr12	8604894	Nonsense_Mutation	novel	*E153Ifs4**	0.06
UCEC	chr12	8605372	Silent	NA	C90C	0.23
UCEC	chr12	8612805	5'UTR	novel		0.31
UCEC	chr12	8605356	Missense_Mutation	NA	D96Y	0.26
UCEC	chr12	8604163	3'UTR	novel		0.43
UCEC	chr12	8606886	Silent	novel	D45D	0.28
UCEC	chr12	8604263	3'UTR	novel		0.25
UCEC	chr12	8612836	5'UTR	novel		0.3
UCEC	chr12	8603630	3'UTR	novel		0.3
UCEC	chr12	8604818	Missense_Mutation	NA	R178C	0.31
UCEC	chr12	8605482	Missense_Mutation	NA	G54S	0.65
UCEC	chr12	8605444	Silent	NA	S66S	0.34
UCEC	chr12	8604884	Missense_Mutation	rs775814283	E156K	0.25
UCEC	chr12	8605331	Missense_Mutation	novel	L104P	0.21	APOBEC_N
UCEC	chr12	8603823	3'UTR	novel		0.41
UCEC	chr12	8605246	Silent	rs763771833	A132A	0.47
UCEC	chr12	8603791	3'UTR	novel		0.36
UCEC	chr12	8605311	Missense_Mutation	NA	A111T	0.43	APOBEC_N
UCEC	chr12	8605242	Frame_Shift_Del	novel	*V134Cfs3**	0.36	APOBEC_N
UCEC	chr12	8605262	Missense_Mutation	NA	R127Q	0.5	APOBEC_N
UCEC	chr12	8604194	3'UTR	novel		0.09
UCEC	chr12	8604156	3'UTR	novel		0.31
UCEC	chr12	8605295	Missense_Mutation	novel	C116Y	0.26	APOBEC_N
UCEC	chr12	8612837	5'UTR	novel		0.56
UCEC	chr12	8605309	Silent	rs374478573	A111A	0.34
UCEC	chr12	8604184	3'UTR	novel		0.21
UCEC	chr12	8606872	Missense_Mutation	rs775067086	R50H	0.22

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
COAD	DEL	0.082	0.087189
DLBC	DEL	0.125	0.11856
LUAD	DEL	0.2016	1.5736e-06
MESO	DEL	0.0805	0.17495
PAAD	DEL	0.1413	0.0019175
READ	DEL	0.1152	0.064633
STAD	DEL	0.1565	0.00030002
TGCT	AMP	0.9467	3.5918e-21
THYM	AMP	0.0325	0.24554

Survival Analysis

Cancer	P-value	Q-value
THYM	0.042	Kaplan-Meier Survival Analysis
HNSC	0.005	Kaplan-Meier Survival Analysis
BRCA	0.043	Kaplan-Meier Survival Analysis
KIRP	0.0009	Kaplan-Meier Survival Analysis
PAAD	0.044	Kaplan-Meier Survival Analysis
CESC	0.011	Kaplan-Meier Survival Analysis
OV	0.025	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000111732 (Gene tree)
Gene ID: 57379
Gene Symbol: AICDA
Alias: HIGM2|CDA2|ARP2|AID
Full Name: activation induced cytidine deaminase
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 10,723 bases
Position: chr12:8,602,166-8,612,888
Accession: 13203
RBP type: canonical RBP
Summary: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000443060	APOBEC_N	PF08210.11	7.5e-61	1	1
ENSP00000229335	APOBEC_N	PF08210.11	7.6e-61	1	1
ENSP00000445691	APOBEC_N	PF08210.11	3.2e-49	1	1
ENSP00000439103	APOBEC_N	PF08210.11	1.8e-43	1	1
ENSP00000439538	APOBEC_N	PF08210.11	1e-09	1	1
ENSP00000443060	APOBEC_C	PF05240.14	1.4e-28	1	1
ENSP00000229335	APOBEC_C	PF05240.14	1.4e-28	1	1
ENSP00000445691	APOBEC_C	PF05240.14	3e-16	1	1
ENSP00000439103	APOBEC_C	PF05240.14	1.9e-10	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
24630719	Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex.	Cell	2014 Mar 13	Hadziselimovic N	doi: 10.1016/j.cell.2014.01.054.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000537228	AICDA-202	667	-	ENSP00000445691	188 (aa)	-	Q9GZX7
ENST00000545512	AICDA-205	592	-	ENSP00000443060	197 (aa)	-	H0YGF6
ENST00000229335	AICDA-201	2819	-	ENSP00000229335	198 (aa)	-	Q9GZX7
ENST00000544516	AICDA-204	206	-	ENSP00000439538	68 (aa)	-	H0YFP1
ENST00000545576	AICDA-206	923	-	-	- (aa)	-	-
ENST00000543081	AICDA-203	1075	XM_011520773	ENSP00000439103	144 (aa)	XP_011519075	H0YFL3

Gene Model

Click here to download ENSG00000111732's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04672	Intestinal immune network for IgA production	KEGG
hsa05340	Primary immunodeficiency	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000111732	Alzheimer Disease	5E-7	26830138
ENSG00000111732	Age of Onset	5E-7	26830138

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000111732	rs3794318	12	8605947	A	Alzheimer disease and age of onset	26830138	unit decrease	5.043	EFO_0000249\|EFO_0004847

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000111732's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000111732	AICDA	99	56.731	ENSAPOG00000023552	aicda	98	58.947	Acanthochromis_polyacanthus
ENSG00000111732	AICDA	99	95.918	ENSAMEG00000007082	AICDA	99	95.918	Ailuropoda_melanoleuca
ENSG00000111732	AICDA	99	59.898	ENSACIG00000012301	aicda	100	59.898	Amphilophus_citrinellus
ENSG00000111732	AICDA	100	58.291	ENSAOCG00000000482	aicda	100	58.291	Amphiprion_ocellaris
ENSG00000111732	AICDA	100	58.291	ENSAPEG00000009755	aicda	100	58.291	Amphiprion_percula
ENSG00000111732	AICDA	99	60.101	ENSATEG00000022035	aicda	97	60.101	Anabas_testudineus
ENSG00000111732	AICDA	99	90.306	ENSAPLG00000013954	AICDA	98	90.306	Anas_platyrhynchos
ENSG00000111732	AICDA	100	85.859	ENSACAG00000017441	AICDA	99	85.859	Anolis_carolinensis
ENSG00000111732	AICDA	100	96.970	ENSANAG00000022438	AICDA	100	96.970	Aotus_nancymaae
ENSG00000111732	AICDA	99	59.898	ENSACLG00000022679	aicda	100	59.898	Astatotilapia_calliptera
ENSG00000111732	AICDA	99	55.844	ENSAMXG00000037242	aicda	65	55.128	Astyanax_mexicanus
ENSG00000111732	AICDA	100	94.472	ENSBTAG00000018849	AICDA	100	94.472	Bos_taurus
ENSG00000111732	AICDA	100	96.970	ENSCJAG00000018856	AICDA	100	96.970	Callithrix_jacchus
ENSG00000111732	AICDA	100	94.949	ENSCAFG00000013897	AICDA	85	94.949	Canis_familiaris
ENSG00000111732	AICDA	100	93.939	ENSCAFG00020003515	AICDA	97	93.939	Canis_lupus_dingo
ENSG00000111732	AICDA	100	91.960	ENSCHIG00000012409	AICDA	100	91.960	Capra_hircus
ENSG00000111732	AICDA	100	95.455	ENSTSYG00000011304	AICDA	100	95.455	Carlito_syrichta
ENSG00000111732	AICDA	98	93.782	ENSCPOG00000039255	-	100	93.782	Cavia_porcellus
ENSG00000111732	AICDA	98	95.337	ENSCPOG00000030440	-	100	95.337	Cavia_porcellus
ENSG00000111732	AICDA	97	92.857	ENSCPOG00000037838	-	100	92.818	Cavia_porcellus
ENSG00000111732	AICDA	97	96.429	ENSCCAG00000030398	AICDA	88	96.429	Cebus_capucinus
ENSG00000111732	AICDA	100	97.475	ENSCATG00000039986	AICDA	100	97.475	Cercocebus_atys
ENSG00000111732	AICDA	99	97.449	ENSCSAG00000009663	AICDA	100	97.449	Chlorocebus_sabaeus
ENSG00000111732	AICDA	97	90.780	ENSCHOG00000010248	AICDA	100	73.367	Choloepus_hoffmanni
ENSG00000111732	AICDA	99	89.286	ENSCPBG00000014337	AICDA	98	89.286	Chrysemys_picta_bellii
ENSG00000111732	AICDA	100	97.475	ENSCANG00000035131	AICDA	100	97.475	Colobus_angolensis_palliatus
ENSG00000111732	AICDA	100	93.939	ENSCGRG00001009654	Aicda	100	93.939	Cricetulus_griseus_chok1gshd
ENSG00000111732	AICDA	100	93.939	ENSCGRG00000013829	Aicda	100	93.939	Cricetulus_griseus_crigri
ENSG00000111732	AICDA	100	56.190	ENSCSEG00000018589	aicda	98	56.190	Cynoglossus_semilaevis
ENSG00000111732	AICDA	99	60.000	ENSCVAG00000001218	aicda	99	60.000	Cyprinodon_variegatus
ENSG00000111732	AICDA	100	60.870	ENSDARG00000015734	aicda	98	60.870	Danio_rerio
ENSG00000111732	AICDA	97	89.286	ENSETEG00000014702	AICDA	99	90.503	Echinops_telfairi
ENSG00000111732	AICDA	100	93.939	ENSEASG00005015947	AICDA	100	93.939	Equus_asinus_asinus
ENSG00000111732	AICDA	100	95.455	ENSECAG00000018578	AICDA	100	95.455	Equus_caballus
ENSG00000111732	AICDA	97	90.714	ENSEEUG00000013899	AICDA	99	91.620	Erinaceus_europaeus
ENSG00000111732	AICDA	99	56.459	ENSELUG00000016293	aicda	98	56.459	Esox_lucius
ENSG00000111732	AICDA	100	95.960	ENSFCAG00000006052	AICDA	85	95.960	Felis_catus
ENSG00000111732	AICDA	99	83.673	ENSFALG00000007261	AICDA	100	83.673	Ficedula_albicollis
ENSG00000111732	AICDA	97	82.857	ENSFDAG00000011141	AICDA	100	85.635	Fukomys_damarensis
ENSG00000111732	AICDA	98	57.282	ENSFHEG00000015733	aicda	99	57.282	Fundulus_heteroclitus
ENSG00000111732	AICDA	100	57.820	ENSGMOG00000004114	aicda	98	57.820	Gadus_morhua
ENSG00000111732	AICDA	100	89.899	ENSGALG00000014280	AICDA	100	89.899	Gallus_gallus
ENSG00000111732	AICDA	99	55.072	ENSGAFG00000013758	aicda	95	55.072	Gambusia_affinis
ENSG00000111732	AICDA	100	54.762	ENSGACG00000010521	aicda	98	54.762	Gasterosteus_aculeatus
ENSG00000111732	AICDA	99	88.265	ENSGAGG00000011838	-	98	88.265	Gopherus_agassizii
ENSG00000111732	AICDA	100	88.384	ENSGAGG00000011839	-	100	88.384	Gopherus_agassizii
ENSG00000111732	AICDA	100	100.000	ENSGGOG00000003338	AICDA	100	100.000	Gorilla_gorilla
ENSG00000111732	AICDA	99	59.898	ENSHBUG00000014333	aicda	100	59.898	Haplochromis_burtoni
ENSG00000111732	AICDA	99	97.449	ENSHGLG00000001443	AICDA	98	97.449	Heterocephalus_glaber_female
ENSG00000111732	AICDA	100	96.970	ENSHGLG00100001381	AICDA	100	96.970	Heterocephalus_glaber_male
ENSG00000111732	AICDA	100	58.706	ENSHCOG00000018886	aicda	100	58.706	Hippocampus_comes
ENSG00000111732	AICDA	100	56.938	ENSIPUG00000007380	aicda	99	56.938	Ictalurus_punctatus
ENSG00000111732	AICDA	100	95.960	ENSSTOG00000010972	AICDA	100	95.960	Ictidomys_tridecemlineatus
ENSG00000111732	AICDA	97	94.286	ENSJJAG00000000908	Aicda	100	95.028	Jaculus_jaculus
ENSG00000111732	AICDA	100	59.799	ENSKMAG00000006359	aicda	100	59.799	Kryptolebias_marmoratus
ENSG00000111732	AICDA	100	55.769	ENSLBEG00000015351	aicda	100	56.667	Labrus_bergylta
ENSG00000111732	AICDA	96	70.290	ENSLACG00000009320	aicda	93	70.290	Latimeria_chalumnae
ENSG00000111732	AICDA	64	65.079	ENSLOCG00000008158	aicda	98	65.079	Lepisosteus_oculatus
ENSG00000111732	AICDA	99	92.308	ENSLAFG00000000721	AICDA	100	92.308	Loxodonta_africana
ENSG00000111732	AICDA	100	97.475	ENSMFAG00000037834	AICDA	100	97.475	Macaca_fascicularis
ENSG00000111732	AICDA	100	97.475	ENSMMUG00000019134	AICDA	100	97.475	Macaca_mulatta
ENSG00000111732	AICDA	100	97.475	ENSMNEG00000043421	AICDA	100	97.475	Macaca_nemestrina
ENSG00000111732	AICDA	75	97.959	ENSMLEG00000039759	-	99	88.757	Mandrillus_leucophaeus
ENSG00000111732	AICDA	100	97.475	ENSMLEG00000040938	AICDA	100	97.475	Mandrillus_leucophaeus
ENSG00000111732	AICDA	100	56.667	ENSMAMG00000020032	aicda	98	56.667	Mastacembelus_armatus
ENSG00000111732	AICDA	99	59.898	ENSMZEG00005016678	aicda	100	59.898	Maylandia_zebra
ENSG00000111732	AICDA	99	89.796	ENSMGAG00000013942	AICDA	100	89.796	Meleagris_gallopavo
ENSG00000111732	AICDA	100	93.939	ENSMAUG00000012229	Aicda	100	93.939	Mesocricetus_auratus
ENSG00000111732	AICDA	100	95.980	ENSMICG00000011695	AICDA	100	95.980	Microcebus_murinus
ENSG00000111732	AICDA	100	93.434	ENSMOCG00000022460	Aicda	100	93.434	Microtus_ochrogaster
ENSG00000111732	AICDA	100	56.667	ENSMMOG00000016707	aicda	98	56.667	Mola_mola
ENSG00000111732	AICDA	98	92.228	ENSMODG00000018002	AICDA	100	92.228	Monodelphis_domestica
ENSG00000111732	AICDA	100	56.190	ENSMALG00000010442	aicda	98	56.190	Monopterus_albus
ENSG00000111732	AICDA	97	92.143	MGP_CAROLIEiJ_G0028824	-	100	92.254	Mus_caroli
ENSG00000111732	AICDA	100	92.424	ENSMUSG00000040627	Aicda	100	93.333	Mus_musculus
ENSG00000111732	AICDA	100	93.434	MGP_PahariEiJ_G0022579	Aicda	100	96.667	Mus_pahari
ENSG00000111732	AICDA	100	92.424	MGP_SPRETEiJ_G0029856	Aicda	100	93.333	Mus_spretus
ENSG00000111732	AICDA	100	95.455	ENSMPUG00000017533	AICDA	94	95.455	Mustela_putorius_furo
ENSG00000111732	AICDA	99	95.408	ENSMLUG00000007881	AICDA	99	95.408	Myotis_lucifugus
ENSG00000111732	AICDA	100	96.465	ENSNGAG00000023430	Aicda	100	96.465	Nannospalax_galili
ENSG00000111732	AICDA	100	56.667	ENSNBRG00000000070	aicda	96	60.000	Neolamprologus_brichardi
ENSG00000111732	AICDA	100	96.465	ENSNLEG00000001917	AICDA	100	96.465	Nomascus_leucogenys
ENSG00000111732	AICDA	99	91.327	ENSMEUG00000006570	AICDA	98	91.327	Notamacropus_eugenii
ENSG00000111732	AICDA	99	89.744	ENSOPRG00000013486	AICDA	100	89.744	Ochotona_princeps
ENSG00000111732	AICDA	99	93.846	ENSODEG00000001235	AICDA	100	93.370	Octodon_degus
ENSG00000111732	AICDA	100	56.190	ENSONIG00000012823	aicda	98	56.190	Oreochromis_niloticus
ENSG00000111732	AICDA	99	94.388	ENSOANG00000007150	AICDA	99	94.388	Ornithorhynchus_anatinus
ENSG00000111732	AICDA	98	94.301	ENSOCUG00000023739	AICDA	100	94.301	Oryctolagus_cuniculus
ENSG00000111732	AICDA	100	58.000	ENSORLG00000011705	aicda	100	58.000	Oryzias_latipes
ENSG00000111732	AICDA	100	58.000	ENSORLG00020006547	aicda	100	58.000	Oryzias_latipes_hni
ENSG00000111732	AICDA	99	58.376	ENSORLG00015012504	aicda	98	58.376	Oryzias_latipes_hsok
ENSG00000111732	AICDA	100	58.000	ENSOMEG00000011880	aicda	98	58.000	Oryzias_melastigma
ENSG00000111732	AICDA	99	97.449	ENSOGAG00000026770	AICDA	99	97.449	Otolemur_garnettii
ENSG00000111732	AICDA	100	91.045	ENSOARG00000001982	AICDA	100	91.045	Ovis_aries
ENSG00000111732	AICDA	100	100.000	ENSPPAG00000038169	AICDA	100	100.000	Pan_paniscus
ENSG00000111732	AICDA	100	95.960	ENSPPRG00000012985	AICDA	100	95.960	Panthera_pardus
ENSG00000111732	AICDA	100	95.960	ENSPTIG00000020074	AICDA	100	95.960	Panthera_tigris_altaica
ENSG00000111732	AICDA	100	99.495	ENSPTRG00000004640	AICDA	100	99.495	Pan_troglodytes
ENSG00000111732	AICDA	100	97.475	ENSPANG00000017883	AICDA	100	97.475	Papio_anubis
ENSG00000111732	AICDA	92	61.579	ENSPKIG00000001499	aicda	100	61.579	Paramormyrops_kingsleyae
ENSG00000111732	AICDA	99	89.796	ENSPSIG00000013283	AICDA	100	89.796	Pelodiscus_sinensis
ENSG00000111732	AICDA	95	58.586	ENSPMGG00000014598	aicda	93	58.794	Periophthalmus_magnuspinnatus
ENSG00000111732	AICDA	100	94.444	ENSPEMG00000008352	Aicda	100	94.444	Peromyscus_maniculatus_bairdii
ENSG00000111732	AICDA	100	93.434	ENSPCIG00000023974	AICDA	100	93.434	Phascolarctos_cinereus
ENSG00000111732	AICDA	95	55.882	ENSPFOG00000011197	aicda	97	52.459	Poecilia_formosa
ENSG00000111732	AICDA	100	55.714	ENSPLAG00000014098	aicda	100	55.714	Poecilia_latipinna
ENSG00000111732	AICDA	100	55.714	ENSPMEG00000024203	aicda	98	55.714	Poecilia_mexicana
ENSG00000111732	AICDA	100	55.714	ENSPREG00000009041	aicda	98	55.714	Poecilia_reticulata
ENSG00000111732	AICDA	99	98.469	ENSPPYG00000004242	AICDA	100	98.469	Pongo_abelii
ENSG00000111732	AICDA	74	84.000	ENSPCAG00000009544	-	54	92.727	Procavia_capensis
ENSG00000111732	AICDA	90	95.082	ENSPCOG00000019228	-	91	95.082	Propithecus_coquereli
ENSG00000111732	AICDA	68	94.776	ENSPCOG00000003380	-	80	94.776	Propithecus_coquereli
ENSG00000111732	AICDA	100	93.939	ENSPVAG00000012185	AICDA	100	93.939	Pteropus_vampyrus
ENSG00000111732	AICDA	99	59.898	ENSPNYG00000000988	aicda	100	59.898	Pundamilia_nyererei
ENSG00000111732	AICDA	100	61.722	ENSPNAG00000019237	aicda	99	62.136	Pygocentrus_nattereri
ENSG00000111732	AICDA	100	93.939	ENSRNOG00000015478	Aicda	100	93.939	Rattus_norvegicus
ENSG00000111732	AICDA	100	97.475	ENSRBIG00000026659	AICDA	100	97.475	Rhinopithecus_bieti
ENSG00000111732	AICDA	100	97.475	ENSRROG00000032866	AICDA	100	97.475	Rhinopithecus_roxellana
ENSG00000111732	AICDA	97	95.714	ENSSBOG00000035758	AICDA	88	95.714	Saimiri_boliviensis_boliviensis
ENSG00000111732	AICDA	100	92.424	ENSSHAG00000008694	AICDA	100	92.424	Sarcophilus_harrisii
ENSG00000111732	AICDA	100	59.420	ENSSFOG00015001695	aicda	98	59.420	Scleropages_formosus
ENSG00000111732	AICDA	99	55.769	ENSSMAG00000012339	aicda	89	55.769	Scophthalmus_maximus
ENSG00000111732	AICDA	99	59.391	ENSSDUG00000009894	aicda	97	59.391	Seriola_dumerili
ENSG00000111732	AICDA	99	59.184	ENSSLDG00000023022	aicda	98	56.190	Seriola_lalandi_dorsalis
ENSG00000111732	AICDA	98	83.420	ENSSPUG00000009022	AICDA	98	83.420	Sphenodon_punctatus
ENSG00000111732	AICDA	100	55.238	ENSSPAG00000021499	aicda	66	55.238	Stegastes_partitus
ENSG00000111732	AICDA	100	93.434	ENSSSCG00000000667	AICDA	100	93.434	Sus_scrofa
ENSG00000111732	AICDA	99	82.653	ENSTGUG00000013115	AICDA	100	82.653	Taeniopygia_guttata
ENSG00000111732	AICDA	99	54.589	ENSTRUG00000007079	aicda	98	54.545	Takifugu_rubripes
ENSG00000111732	AICDA	99	55.238	ENSTNIG00000008118	aicda	98	55.238	Tetraodon_nigroviridis
ENSG00000111732	AICDA	84	90.909	ENSTBEG00000002559	AICDA	100	64.796	Tupaia_belangeri
ENSG00000111732	AICDA	97	93.617	ENSTTRG00000000703	AICDA	100	95.055	Tursiops_truncatus
ENSG00000111732	AICDA	97	95.833	ENSUAMG00000011642	AICDA	98	95.833	Ursus_americanus
ENSG00000111732	AICDA	97	95.833	ENSUMAG00000016540	AICDA	98	95.833	Ursus_maritimus
ENSG00000111732	AICDA	74	95.890	ENSVPAG00000003950	AICDA	99	95.890	Vicugna_pacos
ENSG00000111732	AICDA	99	70.051	ENSXETG00000023905	aicda	98	70.051	Xenopus_tropicalis
ENSG00000111732	AICDA	99	55.612	ENSXCOG00000019386	aicda	90	55.612	Xiphophorus_couchianus
ENSG00000111732	AICDA	99	57.143	ENSXMAG00000011889	aicda	91	57.143	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000178	exosome (RNase complex)	21255825.	IDA	Component
GO:0000932	P-body	21873635.	IBA	Component
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0004126	cytidine deaminase activity	21873635.	IBA	Function
GO:0004126	cytidine deaminase activity	18722174.	IDA	Function
GO:0004126	cytidine deaminase activity	10950930.	NAS	Function
GO:0005515	protein binding	16387847.18722174.19412186.21385873.21518874.21722948.22085931.26867650.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	14769937.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	14769937.18722174.	IDA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0009972	cytidine deamination	-	IEA	Process
GO:0010529	negative regulation of transposition	21873635.	IBA	Process
GO:0016445	somatic diversification of immunoglobulins	18722174.	IDA	Process
GO:0016446	somatic hypermutation of immunoglobulin genes	21518874.	IMP	Process
GO:0016554	cytidine to uridine editing	21873635.	IBA	Process
GO:0030183	B cell differentiation	11007475.	NAS	Process
GO:0031625	ubiquitin protein ligase binding	23277564.	IPI	Function
GO:0033262	regulation of nuclear cell cycle DNA replication	19734146.	IMP	Process
GO:0042742	defense response to bacterium	-	IEA	Process
GO:0042802	identical protein binding	19412186.	IPI	Function
GO:0045190	isotype switching	-	IEA	Process
GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	21873635.	IBA	Process
GO:0051607	defense response to virus	21873635.	IBA	Process
GO:0070383	DNA cytosine deamination	21873635.	IBA	Process
GO:0071222	cellular response to lipopolysaccharide	-	IEA	Process
GO:0080111	DNA demethylation	21873635.	IBA	Process
GO:0080111	DNA demethylation	21496894.	IDA	Process
GO:0090310	negative regulation of methylation-dependent chromatin silencing	21496894.	IDA	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

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Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.