EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23881279	Plakophilin-associated RNA-binding proteins in prostate cancer and their implications in tumor progression and metastasis.	Virchows Arch	2013 Sep	Yang C	doi: 10.1007/s00428-013-1452-y
27606879	RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.	PLoS Genet	2016 Sep 8	Majumder M	doi: 10.1371/journal.pgen.1006306
28767039	FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion.	Elife	2017 Aug 2	Fan Y	doi: 10.7554/eLife.26129.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr3	180968149	Nonsense_Mutation	novel	R433*	0.86
ACC	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.94
BLCA	chr3	180968141	Missense_Mutation	rs746038547	R430Q	0.23
BLCA	chr3	180912733	Silent	NA	Y16Y	0.33
BLCA	chr3	180957881	Nonsense_Mutation	NA	R315*	0.33
BLCA	chr3	180968252	Missense_Mutation	novel	S467Y	0.46
BLCA	chr3	180970289	Missense_Mutation	novel	D512N	0.22
BLCA	chr3	180976169	Silent	rs760920008	N581N	0.26
BLCA	chr3	180957832	Silent	NA	G298G	0.12
BRCA	chr3	180968076	Silent	rs759723969	P408P	0.25
BRCA	chr3	180968091	Silent	NA	S413S	0.29
BRCA	chr3	180962899	Missense_Mutation	NA	R365T	0.34
BRCA	chr3	180976263	Missense_Mutation	NA	E613Q	0.29
BRCA	chr3	180957854	Missense_Mutation	NA	E306Q	0.18
BRCA	chr3	180975337	Missense_Mutation	NA	R543K	0.3
BRCA	chr3	180970162	Silent	NA	L469L	0.29
BRCA	chr3	180951453	Missense_Mutation	rs755691527	F262L	0.13
BRCA	chr3	180976294	3'UTR	novel		0.14
BRCA	chr3	180961505	Missense_Mutation	novel	S343N	0.09
CESC	chr3	180970306	Silent	NA	L517L	0.14
CESC	chr3	180912662	5'UTR	rs761272179		0.26
CESC	chr3	180948777	Frame_Shift_Del	novel	*Y161Tfs8**	0.45
CESC	chr3	180951421	Missense_Mutation	novel	A252T	0.21
CESC	chr3	180968150	Missense_Mutation	rs371485992	R433Q	0.46
CESC	chr3	180976191	Missense_Mutation	rs751470533	D589N	0.36
CESC	chr3	180977064	3'UTR	novel		0.5
CESC	chr3	180935198	Frame_Shift_Del	NA	*E58Kfs8**	0.2
CESC	chr3	180968101	Missense_Mutation	novel	D417H	0.15
CESC	chr3	180948374	Missense_Mutation	NA	D100H	0.18
CESC	chr3	180949250	Silent	novel	K179K	0.09
CESC	chr3	180948487	Missense_Mutation	NA	L137F	0.12
CESC	chr3	180968109	Silent	novel	L419L	0.24
COAD	chr3	180948777	Frame_Shift_Del	novel	*Y161Tfs8**	0.33
COAD	chr3	180949236	Nonsense_Mutation	novel	E175*	0.25
COAD	chr3	180962896	Missense_Mutation	novel	L364P	0.19
COAD	chr3	180975330	Missense_Mutation	novel	I541V	0.27
COAD	chr3	180976171	Missense_Mutation	NA	G582D	0.29
COAD	chr3	180963045	Missense_Mutation	NA	G385R	0.35
COAD	chr3	180957832	Frame_Shift_Del	novel	*N300Mfs8**	0.11
COAD	chr3	180948439	Frame_Shift_Ins	NA	*N124Kfs5**	0.32
COAD	chr3	180948439	Frame_Shift_Ins	NA	*N124Kfs5**	0.3
COAD	chr3	180953776	Frame_Shift_Del	novel	*K274Rfs23**	0.23
COAD	chr3	180963060	Missense_Mutation	NA	R390C	0.24
COAD	chr3	180963040	Nonsense_Mutation	novel	Y383*	0.07
COAD	chr3	180970330	Frame_Shift_Ins	novel	*T526Sfs13**	0.07
COAD	chr3	180962931	Nonsense_Mutation	novel	R376*	0.46
COAD	chr3	180961499	Missense_Mutation	NA	K341T	0.25
COAD	chr3	180976275	Silent	novel	L617L	0.29
ESCA	chr3	180935208	Missense_Mutation	novel	I59V	0.41
ESCA	chr3	180976183	Missense_Mutation	novel	A586V	0.26
ESCA	chr3	180968227	Missense_Mutation	rs199785386	R459C	0.13
ESCA	chr3	180915513	Intron	novel		0.08
ESCA	chr3	180970229	Missense_Mutation	novel	D492N	0.1
GBM	chr3	180976316	3'UTR	novel		0.47
GBM	chr3	180976329	3'UTR	novel		0.4
GBM	chr3	180976330	3'UTR	novel		0.4
GBM	chr3	180949290	Missense_Mutation	NA	R193C	0.55
GBM	chr3	180970262	Missense_Mutation	novel	R503C	0.61
GBM	chr3	180949282	Missense_Mutation	NA	R190Q	0.4
GBM	chr3	180933383	Frame_Shift_Del	novel	*N34Kfs11**	0.23	KH_1
HNSC	chr3	180968201	Missense_Mutation	NA	S450L	0.32
HNSC	chr3	180968080	Missense_Mutation	novel	E410K	0.12
HNSC	chr3	180951342	Silent	novel	V225V	0.08
HNSC	chr3	180975342	Missense_Mutation	novel	E545K	0.24
HNSC	chr3	180970328	Missense_Mutation	novel	D525N	0.06
HNSC	chr3	180970354	Silent	novel	G533G	0.1
HNSC	chr3	180970295	Missense_Mutation	novel	D514H	0.15
HNSC	chr3	180933379	Missense_Mutation	novel	E33Q	0.26	KH_1
KIRP	chr3	180976352	3'UTR	novel		0.48
KIRP	chr3	180970231	Silent	NA	D492D	0.26
LGG	chr3	180968103	Silent	novel	D417D	0.42
LIHC	chr3	180948356	Missense_Mutation	novel	I94V	0.41
LIHC	chr3	180935193	Missense_Mutation	novel	D54Y	0.5
LIHC	chr3	180948394	Silent	novel	I106I	0.1
LUAD	chr3	180957927	Splice_Site	novel	X330_splice	0.23
LUAD	chr3	180953794	Silent	NA	F278F	0.21
LUAD	chr3	180912710	Missense_Mutation	novel	R9C	0.15	KH_1
LUAD	chr3	180975320	Silent	novel	V537V	0.14
LUAD	chr3	180953776	Frame_Shift_Del	novel	*K274Rfs23**	0.18
LUAD	chr3	180968201	Missense_Mutation	NA	S450L	0.22
LUAD	chr3	180949225	Splice_Site	NA	X172_splice	0.11
LUAD	chr3	180957886	Silent	novel	V316V	0.45
LUAD	chr3	180957887	Nonsense_Mutation	novel	R317*	0.45
LUSC	chr3	180968113	Missense_Mutation	novel	D421N	0.27
LUSC	chr3	180976393	3'UTR	novel		0.13
LUSC	chr3	180951363	Silent	novel	L232L	0.57
LUSC	chr3	180968092	Missense_Mutation	novel	E414Q	0.22
LUSC	chr3	180968134	Missense_Mutation	NA	D428N	0.09
LUSC	chr3	180949284	Missense_Mutation	novel	S191G	0.15
LUSC	chr3	180947875	Missense_Mutation	novel	R70T	0.35
LUSC	chr3	180953824	Silent	NA	V288V	0.1
LUSC	chr3	180949282	Missense_Mutation	NA	R190L	0.27
LUSC	chr3	180963007	Splice_Region	novel		0.06
LUSC	chr3	180953761	Splice_Site	NA	X268_splice	0.04
LUSC	chr3	180912723	Missense_Mutation	NA	G13V	0.17	KH_1
LUSC	chr3	180948439	Frame_Shift_Ins	NA	*N124Kfs5**	0.23
LUSC	chr3	180947921	Silent	novel	R85R	0.1
LUSC	chr3	180963046	Missense_Mutation	novel	G385E	0.05
OV	chr3	180968181	Silent	NA	G443G	0.43
OV	chr3	180951301	Missense_Mutation	novel	T212S	0.05
OV	chr3	180968080	Frame_Shift_Ins	NA	*T411Nfs4**	0.24
OV	chr3	180912697	Silent	novel	L4L	0.03
PAAD	chr3	180970281	Missense_Mutation	novel	R509Q	0.06
PAAD	chr3	180948407	Nonsense_Mutation	novel	R111*	0.16
PCPG	chr3	180912708	Missense_Mutation	novel	V8G	0.25	KH_1
PRAD	chr3	180957831	Frame_Shift_Ins	novel	*N300Kfs20**	0.34
READ	chr3	180975375	Nonsense_Mutation	NA	E556*	0.25
READ	chr3	180970295	Missense_Mutation	novel	D514N	0.21
READ	chr3	180957823	Silent	NA	K295K	0.54
READ	chr3	180968215	Missense_Mutation	rs762872016	R455C	0.1
READ	chr3	180948456	Missense_Mutation	novel	F127S	0.13
READ	chr3	180912670	5'UTR	rs751860476		0.3
READ	chr3	180951352	Missense_Mutation	novel	L229V	0.11
READ	chr3	180963042	Missense_Mutation	novel	S384G	0.28
SARC	chr3	180962907	Missense_Mutation	novel	R368C	0.26
SKCM	chr3	180976377	3'UTR	novel		0.46
SKCM	chr3	180963067	Missense_Mutation	NA	G392E	0.31
SKCM	chr3	180968069	Missense_Mutation	NA	S406F	0.2
SKCM	chr3	180970313	Missense_Mutation	NA	G520R	0.09
STAD	chr3	180968159	Missense_Mutation	rs374389670	R436H	0.1
STAD	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.57
STAD	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.31
STAD	chr3	180976150	Missense_Mutation	novel	P575L	0.5
STAD	chr3	180976393	3'UTR	novel		0.3
STAD	chr3	180968216	Missense_Mutation	NA	R455H	0.24
STAD	chr3	180968159	Missense_Mutation	rs374389670	R436H	0.17
STAD	chr3	180976393	3'UTR	novel		0.23
STAD	chr3	180948442	Silent	novel	K122K	0.15
STAD	chr3	180948370	Silent	rs369357473	A98A	0.15
STAD	chr3	180951317	Missense_Mutation	NA	A217V	0.16
STAD	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.35
STAD	chr3	180948433	Silent	NA	K119K	0.22
STAD	chr3	180935197	Frame_Shift_Ins	novel	*E58Rfs3**	0.21
STAD	chr3	180970268	Missense_Mutation	NA	R505W	0.21
UCEC	chr3	180948420	Missense_Mutation	NA	V115D	0.05
UCEC	chr3	180915486	Intron	novel		0.31
UCEC	chr3	180976319	3'UTR	novel		0.26
UCEC	chr3	180970349	Missense_Mutation	NA	N532H	0.31
UCEC	chr3	180976415	3'UTR	novel		0.54
UCEC	chr3	180970260	Missense_Mutation	rs545661459	R502H	0.27
UCEC	chr3	180976234	Missense_Mutation	novel	I603S	0.09
UCEC	chr3	180976493	3'UTR	novel		0.28
UCEC	chr3	180977111	3'UTR	novel		0.35
UCEC	chr3	180949280	Frame_Shift_Del	novel	*R190Yfs10**	0.16
UCEC	chr3	180949282	Missense_Mutation	NA	R190Q	0.15
UCEC	chr3	180970281	Missense_Mutation	novel	R509Q	0.37
UCEC	chr3	180976347	3'UTR	novel		0.37
UCEC	chr3	180962946	Splice_Region	novel		0.3
UCEC	chr3	180976190	Silent	rs765240173	G588G	0.47
UCEC	chr3	180953836	Silent	rs767362600	L292L	0.25
UCEC	chr3	180970176	Missense_Mutation	NA	S474N	0.11
UCEC	chr3	180949298	Missense_Mutation	NA	K195N	0.14
UCEC	chr3	180948377	Missense_Mutation	NA	A101T	0.32
UCEC	chr3	180935152	Missense_Mutation	NA	R40H	0.45	KH_1
UCEC	chr3	180935226	Missense_Mutation	novel	V65I	0.14
UCEC	chr3	180976738	3'UTR	novel		0.36
UCEC	chr3	180915480	Intron	novel		0.32
UCEC	chr3	180957929	Splice_Site	NA	X330_splice	0.37
UCEC	chr3	180948440	Frame_Shift_Del	novel	*N124Yfs4**	0.15
UCEC	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.33
UCEC	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.33
UCEC	chr3	180963001	Intron	novel		0.09
UCEC	chr3	180976124	Frame_Shift_Del	novel	*D568Mfs2**	0.5
UCEC	chr3	180951421	Missense_Mutation	novel	A252T	0.47
UCEC	chr3	180977030	3'UTR	novel		0.53
UCEC	chr3	180970269	Missense_Mutation	novel	R505Q	0.24
UCEC	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.32
UCEC	chr3	180935205	Nonsense_Mutation	novel	E58*	0.38
UCEC	chr3	180949295	Silent	rs779926830	T194T	0.39
UCEC	chr3	180948776	Missense_Mutation	novel	I159V	0.34
UCEC	chr3	180977064	3'UTR	novel		0.6
UCEC	chr3	180951355	Missense_Mutation	novel	M230V	0.19
UCEC	chr3	180975399	Nonsense_Mutation	novel	E564*	0.15
UCEC	chr3	180976289	Silent	novel	S621S	0.28
UCEC	chr3	180976378	3'UTR	novel		0.2
UCEC	chr3	180951462	Silent	rs771379697	Y265Y	0.4
UCEC	chr3	180948407	Nonsense_Mutation	novel	R111*	0.41
UCEC	chr3	180970263	Missense_Mutation	rs143480969	R503H	0.39
UCEC	chr3	180976377	3'UTR	novel		0.36
UCEC	chr3	180976731	3'UTR	novel		0.4
UCEC	chr3	180948440	Frame_Shift_Del	rs756304971	*N124Ifs14**	0.4
UCEC	chr3	180948738	Missense_Mutation	novel	A146V	0.38
UCEC	chr3	180948442	Missense_Mutation	novel	K122N	0.5
UCEC	chr3	180957929	Splice_Site	NA	X330_splice	0.44
UCEC	chr3	180961505	Missense_Mutation	novel	S343N	0.23
UCEC	chr3	180970176	Missense_Mutation	NA	S474N	0.32
UCEC	chr3	180948737	Missense_Mutation	NA	A146T	0.32
UCEC	chr3	180976227	Nonsense_Mutation	novel	E601*	0.06
UCEC	chr3	180968252	Missense_Mutation	novel	S467Y	0.17
UCEC	chr3	180976286	Silent	novel	V620V	0.1
UCEC	chr3	180977094	3'UTR	novel		0.34
UCEC	chr3	180953772	Missense_Mutation	novel	A271D	0.25
UCEC	chr3	180968179	Nonsense_Mutation	novel	G443*	0.22
UCEC	chr3	180915491	Intron	NA		0.39
UCEC	chr3	180970330	Missense_Mutation	rs775129645	D525E	0.29
UCEC	chr3	180948377	Missense_Mutation	NA	A101T	0.07
UCEC	chr3	180977080	3'UTR	novel		0.47
UCEC	chr3	180976192	Missense_Mutation	novel	D589G	0.04
UCEC	chr3	180962981	Intron	novel		0.5
UCEC	chr3	180977073	3'UTR	novel		0.57
UCEC	chr3	180968061	Silent	novel	S403S	0.07
UCEC	chr3	180953777	Missense_Mutation	NA	K273Q	0.48
UCEC	chr3	180976393	3'UTR	novel		0.71
UCEC	chr3	180970269	Missense_Mutation	novel	R505Q	0.46
UCEC	chr3	180948413	Missense_Mutation	NA	R113W	0.5
UCEC	chr3	180975324	Missense_Mutation	NA	D539Y	0.17
UCEC	chr3	180957831	Frame_Shift_Ins	novel	*N300Kfs20**	0.18
UCEC	chr3	180968104	Missense_Mutation	novel	E418K	0.38
UCEC	chr3	180976177	Missense_Mutation	rs371671972	T584I	0.21
UCEC	chr3	180976324	3'UTR	novel		0.13
UCEC	chr3	180948493	Missense_Mutation	NA	E139D	0.32
UCEC	chr3	180957929	Splice_Site	NA	X330_splice	0.27
UCEC	chr3	180948722	Missense_Mutation	novel	C141R	0.62
UCEC	chr3	180953789	Missense_Mutation	NA	G277S	0.48
UCEC	chr3	180962936	Silent	novel	Q377Q	0.43
UCEC	chr3	180976703	3'UTR	novel		0.24
UCEC	chr3	180977132	3'UTR	novel		0.33
UCS	chr3	180970289	Missense_Mutation	novel	D512N	0.34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.4436	0.0018563
HNSC	AMP	0.6897	4.7635e-57
KIRC	AMP	0.1231	2.0306e-05
KIRP	AMP	0.3264	0.15981
LGG	AMP	0.0312	0.0013532
PAAD	AMP	0.1033	0.16151
SARC	DEL	0.1556	0.0086757
TGCT	AMP	0.2533	7.0307e-05

Survival Analysis

Cancer	P-value	Q-value
ACC	0.047	Kaplan-Meier Survival Analysis
HNSC	0.0028	Kaplan-Meier Survival Analysis
SKCM	0.013	Kaplan-Meier Survival Analysis
PRAD	0.03	Kaplan-Meier Survival Analysis
KIRP	0.00011	Kaplan-Meier Survival Analysis
COAD	0.025	Kaplan-Meier Survival Analysis
PAAD	0.0036	Kaplan-Meier Survival Analysis
BLCA	0.042	Kaplan-Meier Survival Analysis
READ	0.03	Kaplan-Meier Survival Analysis
LAML	0.00055	Kaplan-Meier Survival Analysis
KICH	0.011	Kaplan-Meier Survival Analysis
UCEC	0.00076	Kaplan-Meier Survival Analysis
LIHC	0.00025	Kaplan-Meier Survival Analysis
LGG	0.049	Kaplan-Meier Survival Analysis
LUAD	0.001	Kaplan-Meier Survival Analysis
UVM	0.001	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000114416 (Gene tree)
Gene ID: 8087
Gene Symbol: FXR1
Alias: N
Full Name: FMR1 autosomal homolog 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 114,613 bases
Position: chr3:180,868,141-180,982,753
Accession: 4023
RBP type: canonical RBP
Summary: The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000420515	KH_1	PF00013.29	1.7e-16	1	2
ENSP00000420515	KH_1	PF00013.29	1.7e-16	2	2
ENSP00000420643	KH_1	PF00013.29	2e-16	1	2
ENSP00000420643	KH_1	PF00013.29	2e-16	2	2
ENSP00000307633	KH_1	PF00013.29	2.3e-16	1	2
ENSP00000307633	KH_1	PF00013.29	2.3e-16	2	2
ENSP00000388828	KH_1	PF00013.29	2.5e-16	1	2
ENSP00000388828	KH_1	PF00013.29	2.5e-16	2	2
ENSP00000418097	KH_1	PF00013.29	3.2e-16	1	2
ENSP00000418097	KH_1	PF00013.29	3.2e-16	2	2
ENSP00000350170	KH_1	PF00013.29	3.3e-16	1	1
ENSP00000388828	Agenet	PF05641.12	8.8e-15	1	2
ENSP00000388828	Agenet	PF05641.12	8.8e-15	2	2
ENSP00000350170	Agenet	PF05641.12	1.4e-14	1	2
ENSP00000350170	Agenet	PF05641.12	1.4e-14	2	2
ENSP00000417513	Agenet	PF05641.12	1.1e-12	1	1
ENSP00000418097	Agenet	PF05641.12	1.4e-10	1	1
ENSP00000420643	Agenet	PF05641.12	8.1e-06	1	1
ENSP00000420515	FXMRP1_C_core	PF12235.8	9.9e-29	1	2
ENSP00000420515	FXMRP1_C_core	PF12235.8	9.9e-29	2	2
ENSP00000420643	FXMRP1_C_core	PF12235.8	1.4e-28	1	2
ENSP00000420643	FXMRP1_C_core	PF12235.8	1.4e-28	2	2
ENSP00000388828	FXMRP1_C_core	PF12235.8	2.2e-28	1	2
ENSP00000388828	FXMRP1_C_core	PF12235.8	2.2e-28	2	2
ENSP00000307633	FXMRP1_C_core	PF12235.8	2.2e-27	1	2
ENSP00000307633	FXMRP1_C_core	PF12235.8	2.2e-27	2	2
ENSP00000418097	FXMRP1_C_core	PF12235.8	2.5e-27	1	2
ENSP00000418097	FXMRP1_C_core	PF12235.8	2.5e-27	2	2
ENSP00000350170	FXMRP1_C_core	PF12235.8	3.7e-27	1	2
ENSP00000350170	FXMRP1_C_core	PF12235.8	3.7e-27	2	2
ENSP00000418027	FXMRP1_C_core	PF12235.8	2.4e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29101288	Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.	Circulation	2018 Feb 6	Chu M	doi: 10.1161/CIRCULATIONAHA.117.028976
23235829	FMRP targets distinct mRNA sequence elements to regulate protein expression.	Nature	2012 Dec 20	Ascano M Jr	doi: 10.1038/nature11737
21771594	Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery.	FEBS Lett	2011 Aug 19	Goncalves Kde A	doi: 10.1016/j.febslet.2011.07.010
27783624	Correction: RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.	PLoS Genet	2016 Oct 26	Majumder M	doi: 10.1371/journal.pgen.1006411
10546896	Biology of the fragile X mental retardation protein, an RNA-binding protein.	Biochem Cell Biol	1999	Khandjian EW	-
10196376	Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations.	Hum Mol Genet	1999 May	Tamanini F	-
7781595	FXR1, an autosomal homolog of the fragile X mental retardation gene.	EMBO J	1995 Jun 1	Siomi MC	-
11162447	Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle.	Biochem Biophys Res Commun	2000 Dec 29	Ceman S	-
11157796	Evidence that fragile X mental retardation protein is a negative regulator of translation.	Hum Mol Genet	2001 Feb 15	Laggerbauer B	-
11019488	Molecular mechanisms of fragile X syndrome.	J Med Invest	2000 Aug	Inoue SB	-
10912798	Immunocytochemical and biochemical characterization of FMRP, FXR1P, and FXR2P in the mouse.	Exp Cell Res	2000 Jul 10	Bakker CE	-
10888599	The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.	Hum Mol Genet	2000 Jun 12	Tamanini F	-
16000371	The RNA-binding protein fragile X-related 1 regulates somite formation in Xenopus laevis.	Mol Biol Cell	2005 Sep	Huot ME	-
15378363	Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships.	Dev Genes Evol	2004 Nov	Tucker B	-
15128702	Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.	Hum Mol Genet	2004 Jul 1	Mientjes EJ	-
19487368	Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.	Hum Mol Genet	2009 Sep 1	Darnell JC	doi: 10.1093/hmg/ddp255
19276651	Translation regulation of mRNAs by the fragile X family of proteins through the microRNA pathway.	RNA Biol	2009 Apr-Jun	Cheever A	-
18628314	Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients.	J Med Genet	2008 Oct	Davidovic L	doi: 10.1136/jmg.2008.060541
17868361	Posttranscriptional gene expression regulation in CpG-activated macrophages depends on FXR1P RNA-binding protein.	FEMS Immunol Med Microbiol	2007 Nov	Lachance C	-
22730312	Expression of RNA-binding proteins DND1 and FXR1 in the porcine ovary, and during oocyte maturation and early embryo development.	Mol Reprod Dev	2012 Aug	Yang CX	doi: 10.1002/mrd.22059
22522693	Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions.	J Comp Neurol	2012 Nov 1	Akins MR	doi: 10.1002/cne.23123.
22022532	Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.	PLoS One	2011	Cook D	doi: 10.1371/journal.pone.0026120
20197067	FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development.	Dev Biol	2010 May 1	Gessert S	doi: 10.1016/j.ydbio.2010.02.031
28028731	Frameshift Mutation of FXR1 Encoding a RNA-Binding Protein in Gastric and Colorectal Cancers with Microsatellite Instability.	Pathol Oncol Res	2017 Apr	Jo YS	doi: 10.1007/s12253-016-0177-z
25733852	The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers.	Proc Natl Acad Sci U S A	2015 Mar 17	Qian J	doi: 10.1073/pnas.1421975112
25681562	Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development.	Int J Dev Neurosci	2015 May	Bonaccorso CM	doi: 10.1016/j.ijdevneu.2015.02.004
25456134	FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation.	Cell Rep	2014 Nov 20	Cook D	doi: 10.1016/j.celrep.2014.10.028
25225333	Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins.	Mol Cell Biol	2014 Dec 1	Fischer-Keso R	doi: 10.1128/MCB.00766-14
23974796	Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step.	EMBO J	2013 Oct 16	Gumireddy K	doi: 10.1038/emboj.2013.188
23555284	A novel role for the RNA-binding protein FXR1P in myoblasts cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA stability.	PLoS Genet	2013 Mar	Davidovic L	doi: 10.1371/journal.pgen.1003367
23582851	Fragile hearts: new insights into translational control in cardiac muscle.	Trends Cardiovasc Med	2013 Nov	Zarnescu DC	doi: 10.1016/j.tcm.2013.03.003
26844700	MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells.	Cell Death Dis	2016 Feb 4	Cardinali B	doi: 10.1038/cddis.2016.10.
27229378	Regulation of monocyte induced cell migration by the RNA binding protein, FXR1.	Cell Cycle	2016 Jul 17	Le Tonqueze O	doi: 10.1080/15384101.2016.1189040
26240334	FXR1P is a GSK3β substrate regulating mood and emotion processing.	Proc Natl Acad Sci U S A	2015 Aug 18	Del'Guidice T	doi: 10.1073/pnas.1506491112
25962042	Fragile X family members have important and non-overlapping functions.	Biomol Concepts	2011 Oct 1	Winograd C	doi: 10.1515/BMC.2011.033.
28767039	FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion.	Elife	2017 Aug 2	Fan Y	doi: 10.7554/eLife.26129.
29608406	Immunohistochemical Expression of FXR1 in Canine Normal Tissues and Melanomas.	J Histochem Cytochem	2018 Aug	Nordio L	doi: 10.1369/0022155418766292
30151344	Regulation of Adult Neurogenesis by the Fragile X Family of RNA Binding Proteins.	Brain Plast	2018 Aug 10	Patzlaff NE	doi: 10.3233/BPL-170061.
30691465	FXR1 promotes the malignant biological behavior of glioma cells via stabilizing MIR17HG.	J Exp Clin Cancer Res	2019 Jan 28	Cao S	doi: 10.1186/s13046-018-0991-0.
30746571	The RNA-binding protein FXR1 modulates prostate cancer progression by regulating FBXO4.	Funct Integr Genomics	2019 May	Cao H	doi: 10.1007/s10142-019-00661-8
30755307	Muscle-Specific FXR1 Isoforms in Squamous Cell Cancer.	Trends Cancer	2019 Feb	McClure JJ	doi: 10.1016/j.trecan.2018.12.001
30770808	Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy.	Nat Commun	2019 Feb 15	Estan MC	doi: 10.1038/s41467-019-08548-9.
30894247	FXR1 expression domain in Wilms tumor.	J Pediatr Surg	2019 Jun	Phelps HM	doi: 10.1016/j.jpedsurg.2019.02.030

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000461801	FXR1-205	410	-	-	- (aa)	-	-
ENST00000479176	FXR1-213	541	-	-	- (aa)	-	-
ENST00000469882	FXR1-208	570	-	ENSP00000419793	119 (aa)	-	C9JZE0
ENST00000484042	FXR1-217	562	-	ENSP00000417513	151 (aa)	-	C9JAJ4
ENST00000461044	FXR1-204	601	-	-	- (aa)	-	-
ENST00000472339	FXR1-209	2130	-	-	- (aa)	-	-
ENST00000481383	FXR1-215	909	-	-	- (aa)	-	-
ENST00000465551	FXR1-206	572	-	ENSP00000418724	94 (aa)	-	C9IZ22
ENST00000475315	FXR1-211	2341	-	-	- (aa)	-	-
ENST00000473375	FXR1-210	483	-	-	- (aa)	-	-
ENST00000491062	FXR1-220	1768	-	ENSP00000420643	490 (aa)	-	E9PFF5
ENST00000484958	FXR1-219	824	-	ENSP00000419933	123 (aa)	-	C9JY20
ENST00000305586	FXR1-201	3277	XM_006713775	ENSP00000307633	536 (aa)	XP_006713838	P51114
ENST00000491674	FXR1-221	365	-	ENSP00000419047	19 (aa)	-	C9JYQ6
ENST00000476672	FXR1-212	976	-	-	- (aa)	-	-
ENST00000357559	FXR1-202	8711	XM_005247813	ENSP00000350170	621 (aa)	XP_005247870	P51114
ENST00000498658	FXR1-222	683	-	-	- (aa)	-	-
ENST00000445140	FXR1-203	2651	XM_005247816	ENSP00000388828	539 (aa)	XP_005247873	P51114
ENST00000468861	FXR1-207	1989	XM_017007300	ENSP00000420515	454 (aa)	XP_016862789	E7EU85
ENST00000484790	FXR1-218	571	-	ENSP00000417125	75 (aa)	-	C9J5B4
ENST00000480918	FXR1-214	1996	-	ENSP00000418097	608 (aa)	-	B4DXZ6
ENST00000482125	FXR1-216	739	-	ENSP00000418027	246 (aa)	-	H7C4S4

Gene Model

Click here to download ENSG00000114416's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000114416	Gallbladder Diseases	8.11426262097292E-5	-
ENSG00000114416	Bipolar Disorder	4E-6	26433762
ENSG00000114416	Binge-Eating Disorder	4E-6	26433762
ENSG00000114416	Bipolar Disorder	1E-6	26433762
ENSG00000114416	Binge-Eating Disorder	1E-6	26433762

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000114416	rs1805576	3	180949777	G	Bipolar disorder and eating disorder	26433762	[NR]	1.79	EFO_0005203\|EFO_0000289
ENSG00000114416	rs1805576	3	180949777	G	Eating disorder in bipolar disorder	26433762	[NR]	1.71	EFO_0005203\|EFO_0000289
ENSG00000114416	rs13096210	3	180881530	C	Schizophrenia	26198764	[NR]	1.1363636	EFO_0000692
ENSG00000114416	rs519618	3	180946882	?	General cognitive ability	29844566	z-score decrease	5.006	EFO_0004337
ENSG00000114416	rs768882952	3	180940263	?	Reaction time	29844566	[0.0042-0.0108] unit decrease	0.0075016	EFO_0008393
ENSG00000114416	rs34796896	3	180905467	?	Schizophrenia	29483656	[1.06-1.11]	1.087	EFO_0000692
ENSG00000114416	rs115732722	3	180973246	A	Educational attainment (years of education)	30038396	[0.027-0.056] unit decrease	0.0415	EFO_0004784
ENSG00000114416	rs34796896	3	180905467	G	Schizophrenia	30285260	[1.06-1.11]	1.086	EFO_0000692

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000114416's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000114416	FXR1	95	77.465	ENSG00000102081	FMR1	95	79.381
ENSG00000114416	FXR1	100	76.000	ENSG00000129245	FXR2	99	77.778

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000114416	FXR1	100	69.106	ENSAPOG00000003062	fxr2	98	58.219	Acanthochromis_polyacanthus
ENSG00000114416	FXR1	95	77.465	ENSAPOG00000006422	fmr1	78	64.544	Acanthochromis_polyacanthus
ENSG00000114416	FXR1	99	83.784	ENSAPOG00000017058	fxr1	100	64.265	Acanthochromis_polyacanthus
ENSG00000114416	FXR1	100	100.000	ENSAMEG00000012185	FXR1	100	90.950	Ailuropoda_melanoleuca
ENSG00000114416	FXR1	95	77.465	ENSAMEG00000014996	FMR1	72	74.251	Ailuropoda_melanoleuca
ENSG00000114416	FXR1	100	76.000	ENSAMEG00000016775	FXR2	98	57.485	Ailuropoda_melanoleuca
ENSG00000114416	FXR1	100	76.423	ENSACIG00000023354	fxr1	97	69.671	Amphilophus_citrinellus
ENSG00000114416	FXR1	95	74.648	ENSACIG00000022552	fmr1	84	65.533	Amphilophus_citrinellus
ENSG00000114416	FXR1	100	70.732	ENSACIG00000021149	fxr2	100	54.247	Amphilophus_citrinellus
ENSG00000114416	FXR1	95	77.465	ENSAOCG00000008025	fmr1	86	65.021	Amphiprion_ocellaris
ENSG00000114416	FXR1	99	83.784	ENSAOCG00000022178	fxr1	97	71.039	Amphiprion_ocellaris
ENSG00000114416	FXR1	100	69.106	ENSAOCG00000007975	fxr2	98	58.562	Amphiprion_ocellaris
ENSG00000114416	FXR1	99	83.784	ENSAPEG00000014981	fxr1	97	69.608	Amphiprion_percula
ENSG00000114416	FXR1	95	77.465	ENSAPEG00000015355	fmr1	78	64.195	Amphiprion_percula
ENSG00000114416	FXR1	100	69.106	ENSAPEG00000017208	fxr2	98	58.390	Amphiprion_percula
ENSG00000114416	FXR1	100	70.732	ENSATEG00000019423	fxr2	100	56.250	Anabas_testudineus
ENSG00000114416	FXR1	95	77.465	ENSATEG00000017772	fmr1	78	65.032	Anabas_testudineus
ENSG00000114416	FXR1	99	78.378	ENSATEG00000022488	fxr1	99	65.564	Anabas_testudineus
ENSG00000114416	FXR1	100	97.333	ENSAPLG00000010032	FXR1	100	84.708	Anas_platyrhynchos
ENSG00000114416	FXR1	95	76.056	ENSAPLG00000003811	FMR1	75	73.041	Anas_platyrhynchos
ENSG00000114416	FXR1	100	92.000	ENSACAG00000003918	FXR1	100	83.634	Anolis_carolinensis
ENSG00000114416	FXR1	95	77.465	ENSACAG00000007899	FMR1	73	73.101	Anolis_carolinensis
ENSG00000114416	FXR1	99	39.655	ENSACAG00000000561	-	95	39.792	Anolis_carolinensis
ENSG00000114416	FXR1	100	100.000	ENSANAG00000026001	FXR1	100	100.000	Aotus_nancymaae
ENSG00000114416	FXR1	100	76.000	ENSANAG00000023710	FXR2	98	57.664	Aotus_nancymaae
ENSG00000114416	FXR1	95	77.465	ENSANAG00000026715	FMR1	99	74.830	Aotus_nancymaae
ENSG00000114416	FXR1	100	70.732	ENSACLG00000010657	fxr2	100	56.028	Astatotilapia_calliptera
ENSG00000114416	FXR1	95	74.648	ENSACLG00000021559	fmr1	78	64.744	Astatotilapia_calliptera
ENSG00000114416	FXR1	99	81.081	ENSACLG00000025812	fxr1	100	62.375	Astatotilapia_calliptera
ENSG00000114416	FXR1	99	83.784	ENSAMXG00000001357	fxr1	100	71.822	Astyanax_mexicanus
ENSG00000114416	FXR1	100	73.333	ENSAMXG00000003585	fxr2	99	57.206	Astyanax_mexicanus
ENSG00000114416	FXR1	95	76.056	ENSAMXG00000000371	fmr1	80	66.521	Astyanax_mexicanus
ENSG00000114416	FXR1	100	100.000	ENSBTAG00000016457	FXR1	100	99.814	Bos_taurus
ENSG00000114416	FXR1	100	76.000	ENSBTAG00000005462	FXR2	95	61.626	Bos_taurus
ENSG00000114416	FXR1	95	77.465	ENSBTAG00000012552	FMR1	72	74.251	Bos_taurus
ENSG00000114416	FXR1	100	100.000	ENSCJAG00000012802	FXR1	100	100.000	Callithrix_jacchus
ENSG00000114416	FXR1	95	77.465	ENSCJAG00000003925	FMR1	99	74.830	Callithrix_jacchus
ENSG00000114416	FXR1	100	76.000	ENSCJAG00000015063	FXR2	98	57.664	Callithrix_jacchus
ENSG00000114416	FXR1	100	100.000	ENSCAFG00000011582	FXR1	100	99.814	Canis_familiaris
ENSG00000114416	FXR1	95	77.465	ENSCAFG00000019085	FMR1	74	74.251	Canis_familiaris
ENSG00000114416	FXR1	100	76.000	ENSCAFG00000016685	FXR2	98	57.602	Canis_familiaris
ENSG00000114416	FXR1	100	76.000	ENSCAFG00020007819	FXR2	98	58.102	Canis_lupus_dingo
ENSG00000114416	FXR1	100	100.000	ENSCAFG00020023527	FXR1	100	99.678	Canis_lupus_dingo
ENSG00000114416	FXR1	95	77.465	ENSCAFG00020024366	FMR1	81	74.251	Canis_lupus_dingo
ENSG00000114416	FXR1	95	77.465	ENSCHIG00000000198	FMR1	72	73.952	Capra_hircus
ENSG00000114416	FXR1	100	100.000	ENSCHIG00000017202	FXR1	100	99.517	Capra_hircus
ENSG00000114416	FXR1	100	76.000	ENSCHIG00000004007	FXR2	98	57.956	Capra_hircus
ENSG00000114416	FXR1	100	100.000	ENSTSYG00000001610	FXR1	100	99.629	Carlito_syrichta
ENSG00000114416	FXR1	95	77.465	ENSTSYG00000014392	FMR1	95	74.205	Carlito_syrichta
ENSG00000114416	FXR1	100	74.667	ENSTSYG00000004564	FXR2	98	58.841	Carlito_syrichta
ENSG00000114416	FXR1	100	100.000	ENSCAPG00000007992	FXR1	100	89.800	Cavia_aperea
ENSG00000114416	FXR1	100	76.000	ENSCAPG00000006378	FXR2	99	57.794	Cavia_aperea
ENSG00000114416	FXR1	95	76.056	ENSCAPG00000008575	FMR1	79	51.501	Cavia_aperea
ENSG00000114416	FXR1	100	100.000	ENSCPOG00000010418	FXR1	100	99.034	Cavia_porcellus
ENSG00000114416	FXR1	100	76.000	ENSCPOG00000023303	FXR2	95	60.091	Cavia_porcellus
ENSG00000114416	FXR1	95	76.056	ENSCPOG00000003723	FMR1	75	73.418	Cavia_porcellus
ENSG00000114416	FXR1	100	100.000	ENSCCAG00000025006	FXR1	97	98.507	Cebus_capucinus
ENSG00000114416	FXR1	99	60.777	ENSCCAG00000013516	FXR2	98	55.036	Cebus_capucinus
ENSG00000114416	FXR1	95	77.465	ENSCCAG00000021737	FMR1	99	74.830	Cebus_capucinus
ENSG00000114416	FXR1	95	77.465	ENSCATG00000038319	FMR1	99	74.830	Cercocebus_atys
ENSG00000114416	FXR1	100	100.000	ENSCATG00000040925	FXR1	100	100.000	Cercocebus_atys
ENSG00000114416	FXR1	100	76.000	ENSCATG00000039859	FXR2	98	57.810	Cercocebus_atys
ENSG00000114416	FXR1	95	76.056	ENSCLAG00000001233	FMR1	74	73.418	Chinchilla_lanigera
ENSG00000114416	FXR1	100	76.000	ENSCLAG00000007322	FXR2	98	58.333	Chinchilla_lanigera
ENSG00000114416	FXR1	100	100.000	ENSCLAG00000014182	FXR1	100	98.873	Chinchilla_lanigera
ENSG00000114416	FXR1	100	100.000	ENSCSAG00000013179	FXR1	100	95.833	Chlorocebus_sabaeus
ENSG00000114416	FXR1	95	77.465	ENSCSAG00000007281	FMR1	81	63.434	Chlorocebus_sabaeus
ENSG00000114416	FXR1	100	76.000	ENSCSAG00000011386	FXR2	98	57.810	Chlorocebus_sabaeus
ENSG00000114416	FXR1	100	59.350	ENSCHOG00000013177	-	54	68.421	Choloepus_hoffmanni
ENSG00000114416	FXR1	100	100.000	ENSCHOG00000012877	FXR1	86	100.000	Choloepus_hoffmanni
ENSG00000114416	FXR1	100	98.667	ENSCPBG00000000223	FXR1	100	90.937	Chrysemys_picta_bellii
ENSG00000114416	FXR1	95	76.056	ENSCPBG00000020840	FMR1	82	68.182	Chrysemys_picta_bellii
ENSG00000114416	FXR1	100	77.333	ENSCPBG00000004747	FXR2	68	77.143	Chrysemys_picta_bellii
ENSG00000114416	FXR1	95	47.222	ENSCING00000008519	-	91	51.049	Ciona_intestinalis
ENSG00000114416	FXR1	95	48.611	ENSCSAVG00000007423	-	90	51.014	Ciona_savignyi
ENSG00000114416	FXR1	95	77.465	ENSCANG00000033482	FMR1	99	74.830	Colobus_angolensis_palliatus
ENSG00000114416	FXR1	100	76.000	ENSCANG00000039094	FXR2	98	57.810	Colobus_angolensis_palliatus
ENSG00000114416	FXR1	99	100.000	ENSCANG00000028959	FXR1	100	100.000	Colobus_angolensis_palliatus
ENSG00000114416	FXR1	95	76.056	ENSCGRG00001012567	Fmr1	80	73.653	Cricetulus_griseus_chok1gshd
ENSG00000114416	FXR1	100	100.000	ENSCGRG00001024795	Fxr1	100	98.390	Cricetulus_griseus_chok1gshd
ENSG00000114416	FXR1	100	76.000	ENSCGRG00001000488	Fxr2	98	57.910	Cricetulus_griseus_chok1gshd
ENSG00000114416	FXR1	95	76.056	ENSCGRG00000005009	Fmr1	78	72.327	Cricetulus_griseus_crigri
ENSG00000114416	FXR1	100	76.000	ENSCGRG00000012580	Fxr2	100	57.185	Cricetulus_griseus_crigri
ENSG00000114416	FXR1	100	100.000	ENSCGRG00000000624	Fxr1	97	98.344	Cricetulus_griseus_crigri
ENSG00000114416	FXR1	100	65.546	ENSCSEG00000016308	fmr1	79	68.254	Cynoglossus_semilaevis
ENSG00000114416	FXR1	100	70.667	ENSCSEG00000013667	fxr2	100	54.993	Cynoglossus_semilaevis
ENSG00000114416	FXR1	99	81.081	ENSCSEG00000001597	fxr1	100	66.667	Cynoglossus_semilaevis
ENSG00000114416	FXR1	99	85.135	ENSCVAG00000000711	fxr1	100	63.324	Cyprinodon_variegatus
ENSG00000114416	FXR1	100	68.000	ENSCVAG00000008490	fxr2	99	59.891	Cyprinodon_variegatus
ENSG00000114416	FXR1	95	73.239	ENSCVAG00000011644	fmr1	82	69.501	Cyprinodon_variegatus
ENSG00000114416	FXR1	100	70.732	ENSDARG00000016260	fxr2	99	62.755	Danio_rerio
ENSG00000114416	FXR1	99	79.730	ENSDARG00000022968	fxr1	98	72.846	Danio_rerio
ENSG00000114416	FXR1	95	76.056	ENSDARG00000037433	fmr1	80	65.570	Danio_rerio
ENSG00000114416	FXR1	95	76.056	ENSDNOG00000019486	FMR1	72	73.653	Dasypus_novemcinctus
ENSG00000114416	FXR1	100	76.000	ENSDNOG00000001047	FXR2	98	57.664	Dasypus_novemcinctus
ENSG00000114416	FXR1	97	70.168	ENSDNOG00000032775	-	100	63.668	Dasypus_novemcinctus
ENSG00000114416	FXR1	100	100.000	ENSDNOG00000019065	-	100	99.780	Dasypus_novemcinctus
ENSG00000114416	FXR1	99	98.776	ENSDORG00000005853	Fxr1	100	95.775	Dipodomys_ordii
ENSG00000114416	FXR1	100	76.000	ENSDORG00000014232	Fxr2	100	58.036	Dipodomys_ordii
ENSG00000114416	FXR1	95	76.056	ENSDORG00000012501	Fmr1	79	74.251	Dipodomys_ordii
ENSG00000114416	FXR1	100	36.975	FBgn0028734	Fmr1	71	49.086	Drosophila_melanogaster
ENSG00000114416	FXR1	95	74.648	ENSETEG00000006061	FMR1	57	75.862	Echinops_telfairi
ENSG00000114416	FXR1	100	99.187	ENSETEG00000006891	FXR1	100	97.345	Echinops_telfairi
ENSG00000114416	FXR1	100	74.667	ENSETEG00000018613	FXR2	94	58.089	Echinops_telfairi
ENSG00000114416	FXR1	95	60.563	ENSEBUG00000008785	fmr1	94	43.942	Eptatretus_burgeri
ENSG00000114416	FXR1	99	77.027	ENSEBUG00000005529	fxr1	97	62.166	Eptatretus_burgeri
ENSG00000114416	FXR1	95	77.465	ENSEASG00005014017	FMR1	87	58.700	Equus_asinus_asinus
ENSG00000114416	FXR1	100	99.187	ENSEASG00005016818	FXR1	100	95.370	Equus_asinus_asinus
ENSG00000114416	FXR1	100	76.000	ENSEASG00005019301	FXR2	98	58.102	Equus_asinus_asinus
ENSG00000114416	FXR1	95	77.465	ENSECAG00000032767	FMR1	81	63.232	Equus_caballus
ENSG00000114416	FXR1	100	99.629	ENSECAG00000007560	FXR1	100	99.629	Equus_caballus
ENSG00000114416	FXR1	100	76.000	ENSECAG00000007051	FXR2	98	57.956	Equus_caballus
ENSG00000114416	FXR1	100	76.000	ENSEEUG00000013410	FXR2	94	55.606	Erinaceus_europaeus
ENSG00000114416	FXR1	100	100.000	ENSEEUG00000006823	FXR1	99	98.226	Erinaceus_europaeus
ENSG00000114416	FXR1	72	61.775	ENSEEUG00000015366	FMR1	68	61.775	Erinaceus_europaeus
ENSG00000114416	FXR1	95	73.239	ENSELUG00000013325	fmr1	79	63.559	Esox_lucius
ENSG00000114416	FXR1	100	78.862	ENSELUG00000012917	fxr1	97	71.143	Esox_lucius
ENSG00000114416	FXR1	100	66.406	ENSELUG00000023014	fxr2	94	58.806	Esox_lucius
ENSG00000114416	FXR1	100	98.667	ENSFCAG00000022259	FXR1	99	93.554	Felis_catus
ENSG00000114416	FXR1	100	76.000	ENSFCAG00000009620	FXR2	98	57.810	Felis_catus
ENSG00000114416	FXR1	95	77.465	ENSFCAG00000007228	FMR1	72	74.251	Felis_catus
ENSG00000114416	FXR1	100	97.333	ENSFALG00000008301	FXR1	95	84.848	Ficedula_albicollis
ENSG00000114416	FXR1	95	76.056	ENSFALG00000012085	FMR1	84	67.749	Ficedula_albicollis
ENSG00000114416	FXR1	95	76.056	ENSFDAG00000017613	FMR1	72	74.367	Fukomys_damarensis
ENSG00000114416	FXR1	100	100.000	ENSFDAG00000019934	FXR1	100	99.344	Fukomys_damarensis
ENSG00000114416	FXR1	100	74.667	ENSFDAG00000013401	FXR2	99	58.333	Fukomys_damarensis
ENSG00000114416	FXR1	50	86.667	ENSFHEG00000003734	-	99	86.667	Fundulus_heteroclitus
ENSG00000114416	FXR1	95	77.465	ENSFHEG00000000636	fmr1	78	64.544	Fundulus_heteroclitus
ENSG00000114416	FXR1	72	56.742	ENSFHEG00000003714	fxr1	86	69.778	Fundulus_heteroclitus
ENSG00000114416	FXR1	100	69.333	ENSFHEG00000023088	fxr2	99	56.477	Fundulus_heteroclitus
ENSG00000114416	FXR1	100	67.480	ENSGMOG00000011293	fxr2	71	61.426	Gadus_morhua
ENSG00000114416	FXR1	99	71.622	ENSGMOG00000006141	fmr1	88	65.148	Gadus_morhua
ENSG00000114416	FXR1	100	80.000	ENSGMOG00000000446	fxr1	88	80.168	Gadus_morhua
ENSG00000114416	FXR1	95	76.056	ENSGALG00000009177	FMR1	84	67.965	Gallus_gallus
ENSG00000114416	FXR1	100	97.333	ENSGALG00000008864	FXR1	99	91.089	Gallus_gallus
ENSG00000114416	FXR1	99	82.432	ENSGAFG00000010906	fxr1	100	63.861	Gambusia_affinis
ENSG00000114416	FXR1	100	69.333	ENSGAFG00000001957	fxr2	99	56.769	Gambusia_affinis
ENSG00000114416	FXR1	99	74.324	ENSGAFG00000015494	fmr1	70	64.018	Gambusia_affinis
ENSG00000114416	FXR1	99	82.432	ENSGACG00000006052	fxr1	95	67.727	Gasterosteus_aculeatus
ENSG00000114416	FXR1	95	74.648	ENSGACG00000018742	fmr1	79	67.342	Gasterosteus_aculeatus
ENSG00000114416	FXR1	100	67.480	ENSGACG00000019983	fxr2	100	55.021	Gasterosteus_aculeatus
ENSG00000114416	FXR1	100	98.667	ENSGAGG00000025290	FXR1	100	88.391	Gopherus_agassizii
ENSG00000114416	FXR1	95	76.056	ENSGAGG00000024559	FMR1	80	67.111	Gopherus_agassizii
ENSG00000114416	FXR1	95	77.465	ENSGGOG00000010373	FMR1	99	73.285	Gorilla_gorilla
ENSG00000114416	FXR1	100	76.000	ENSGGOG00000024357	FXR2	98	57.810	Gorilla_gorilla
ENSG00000114416	FXR1	100	100.000	ENSGGOG00000009957	-	100	100.000	Gorilla_gorilla
ENSG00000114416	FXR1	100	70.732	ENSHBUG00000009073	fxr2	100	55.887	Haplochromis_burtoni
ENSG00000114416	FXR1	99	81.081	ENSHBUG00000004901	fxr1	100	62.661	Haplochromis_burtoni
ENSG00000114416	FXR1	95	74.648	ENSHBUG00000012534	fmr1	88	65.801	Haplochromis_burtoni
ENSG00000114416	FXR1	100	76.000	ENSHGLG00000012247	FXR2	98	58.272	Heterocephalus_glaber_female
ENSG00000114416	FXR1	100	100.000	ENSHGLG00000018814	FXR1	100	99.034	Heterocephalus_glaber_female
ENSG00000114416	FXR1	95	76.056	ENSHGLG00000000576	FMR1	73	74.251	Heterocephalus_glaber_female
ENSG00000114416	FXR1	95	76.056	ENSHGLG00100008323	FMR1	84	62.062	Heterocephalus_glaber_male
ENSG00000114416	FXR1	100	100.000	ENSHGLG00100017463	FXR1	100	99.443	Heterocephalus_glaber_male
ENSG00000114416	FXR1	100	76.000	ENSHGLG00100018506	FXR2	98	57.247	Heterocephalus_glaber_male
ENSG00000114416	FXR1	100	73.171	ENSHCOG00000010198	FXR1	100	74.733	Hippocampus_comes
ENSG00000114416	FXR1	100	68.000	ENSHCOG00000010418	fxr2	100	53.890	Hippocampus_comes
ENSG00000114416	FXR1	100	73.171	ENSHCOG00000010273	fxr1	84	75.641	Hippocampus_comes
ENSG00000114416	FXR1	100	73.171	ENSHCOG00000010337	fxr1	99	64.111	Hippocampus_comes
ENSG00000114416	FXR1	95	73.239	ENSHCOG00000004757	fmr1	83	61.966	Hippocampus_comes
ENSG00000114416	FXR1	100	82.667	ENSIPUG00000024597	fxr1	100	65.496	Ictalurus_punctatus
ENSG00000114416	FXR1	100	70.667	ENSIPUG00000022953	fxr2	99	59.789	Ictalurus_punctatus
ENSG00000114416	FXR1	95	76.056	ENSIPUG00000014418	fmr1-b	85	65.035	Ictalurus_punctatus
ENSG00000114416	FXR1	100	76.000	ENSSTOG00000005657	FXR2	98	58.626	Ictidomys_tridecemlineatus
ENSG00000114416	FXR1	100	100.000	ENSSTOG00000010612	FXR1	100	99.195	Ictidomys_tridecemlineatus
ENSG00000114416	FXR1	95	76.056	ENSSTOG00000003260	FMR1	81	63.030	Ictidomys_tridecemlineatus
ENSG00000114416	FXR1	99	70.270	ENSJJAG00000008538	-	97	73.810	Jaculus_jaculus
ENSG00000114416	FXR1	100	76.000	ENSJJAG00000016434	Fxr2	98	58.721	Jaculus_jaculus
ENSG00000114416	FXR1	99	98.374	ENSJJAG00000019175	Fxr1	100	95.815	Jaculus_jaculus
ENSG00000114416	FXR1	100	69.333	ENSKMAG00000014569	fxr2	99	57.164	Kryptolebias_marmoratus
ENSG00000114416	FXR1	99	86.486	ENSKMAG00000004687	fxr1	100	60.231	Kryptolebias_marmoratus
ENSG00000114416	FXR1	99	74.324	ENSKMAG00000006554	fmr1	90	64.882	Kryptolebias_marmoratus
ENSG00000114416	FXR1	99	81.081	ENSLBEG00000015038	fxr1	99	67.886	Labrus_bergylta
ENSG00000114416	FXR1	99	81.081	ENSLBEG00000011791	-	99	69.391	Labrus_bergylta
ENSG00000114416	FXR1	95	77.465	ENSLBEG00000014381	fmr1	80	62.340	Labrus_bergylta
ENSG00000114416	FXR1	100	68.293	ENSLBEG00000000923	fxr2	97	60.788	Labrus_bergylta
ENSG00000114416	FXR1	100	76.000	ENSLACG00000006238	FXR2	97	65.529	Latimeria_chalumnae
ENSG00000114416	FXR1	100	84.000	ENSLACG00000011290	FXR1	100	79.601	Latimeria_chalumnae
ENSG00000114416	FXR1	95	74.648	ENSLACG00000005358	FMR1	61	76.923	Latimeria_chalumnae
ENSG00000114416	FXR1	95	77.465	ENSLOCG00000015397	fmr1	81	61.569	Lepisosteus_oculatus
ENSG00000114416	FXR1	100	88.000	ENSLOCG00000000589	fxr1	100	72.117	Lepisosteus_oculatus
ENSG00000114416	FXR1	85	74.419	ENSLOCG00000013240	fxr2	100	42.517	Lepisosteus_oculatus
ENSG00000114416	FXR1	95	77.465	ENSLAFG00000013592	FMR1	73	71.257	Loxodonta_africana
ENSG00000114416	FXR1	100	76.000	ENSLAFG00000001114	FXR2	100	57.919	Loxodonta_africana
ENSG00000114416	FXR1	100	100.000	ENSLAFG00000001908	FXR1	100	98.873	Loxodonta_africana
ENSG00000114416	FXR1	100	100.000	ENSMFAG00000040264	FXR1	100	100.000	Macaca_fascicularis
ENSG00000114416	FXR1	95	77.465	ENSMFAG00000000241	FMR1	99	74.830	Macaca_fascicularis
ENSG00000114416	FXR1	100	76.000	ENSMFAG00000043282	FXR2	98	57.810	Macaca_fascicularis
ENSG00000114416	FXR1	95	77.465	ENSMMUG00000015814	FMR1	99	74.830	Macaca_mulatta
ENSG00000114416	FXR1	100	100.000	ENSMMUG00000012105	FXR1	100	100.000	Macaca_mulatta
ENSG00000114416	FXR1	100	76.000	ENSMMUG00000013510	FXR2	98	57.810	Macaca_mulatta
ENSG00000114416	FXR1	100	100.000	ENSMNEG00000031733	FXR1	100	100.000	Macaca_nemestrina
ENSG00000114416	FXR1	100	76.000	ENSMNEG00000031195	FXR2	98	57.810	Macaca_nemestrina
ENSG00000114416	FXR1	95	77.465	ENSMNEG00000024342	FMR1	99	74.830	Macaca_nemestrina
ENSG00000114416	FXR1	100	100.000	ENSMLEG00000041270	FXR1	100	100.000	Mandrillus_leucophaeus
ENSG00000114416	FXR1	95	77.465	ENSMLEG00000035664	FMR1	99	74.830	Mandrillus_leucophaeus
ENSG00000114416	FXR1	100	76.000	ENSMLEG00000034764	FXR2	99	57.810	Mandrillus_leucophaeus
ENSG00000114416	FXR1	95	74.648	ENSMAMG00000000787	fmr1	78	63.866	Mastacembelus_armatus
ENSG00000114416	FXR1	100	70.732	ENSMAMG00000004616	fxr2	100	55.540	Mastacembelus_armatus
ENSG00000114416	FXR1	99	83.784	ENSMAMG00000012607	fxr1	100	67.216	Mastacembelus_armatus
ENSG00000114416	FXR1	99	81.081	ENSMZEG00005015679	fxr1	100	62.554	Maylandia_zebra
ENSG00000114416	FXR1	100	70.161	ENSMZEG00005007512	FXR2	98	60.436	Maylandia_zebra
ENSG00000114416	FXR1	100	70.732	ENSMZEG00005028541	fxr2	100	57.184	Maylandia_zebra
ENSG00000114416	FXR1	95	74.648	ENSMZEG00005005455	fmr1	78	64.744	Maylandia_zebra
ENSG00000114416	FXR1	100	97.333	ENSMGAG00000009602	FXR1	100	86.076	Meleagris_gallopavo
ENSG00000114416	FXR1	95	76.056	ENSMGAG00000008270	FMR1	81	67.040	Meleagris_gallopavo
ENSG00000114416	FXR1	100	76.000	ENSMAUG00000002021	Fxr2	98	58.309	Mesocricetus_auratus
ENSG00000114416	FXR1	100	100.000	ENSMAUG00000001188	Fxr1	100	98.390	Mesocricetus_auratus
ENSG00000114416	FXR1	95	76.056	ENSMAUG00000000336	-	92	72.481	Mesocricetus_auratus
ENSG00000114416	FXR1	100	100.000	ENSMICG00000048978	-	100	96.111	Microcebus_murinus
ENSG00000114416	FXR1	100	86.593	ENSMICG00000033163	-	100	84.818	Microcebus_murinus
ENSG00000114416	FXR1	100	76.000	ENSMICG00000014799	FXR2	98	57.749	Microcebus_murinus
ENSG00000114416	FXR1	99	74.324	ENSMICG00000000838	FMR1	99	74.490	Microcebus_murinus
ENSG00000114416	FXR1	100	76.000	ENSMOCG00000019049	Fxr2	98	58.370	Microtus_ochrogaster
ENSG00000114416	FXR1	100	100.000	ENSMOCG00000017707	Fxr1	100	99.425	Microtus_ochrogaster
ENSG00000114416	FXR1	95	76.056	ENSMOCG00000005190	Fmr1	78	73.054	Microtus_ochrogaster
ENSG00000114416	FXR1	100	69.919	ENSMMOG00000012192	fxr2	88	61.017	Mola_mola
ENSG00000114416	FXR1	99	75.676	ENSMMOG00000010038	fmr1	77	65.076	Mola_mola
ENSG00000114416	FXR1	99	82.432	ENSMMOG00000001546	fxr1	99	71.002	Mola_mola
ENSG00000114416	FXR1	95	74.648	ENSMODG00000005550	FMR1	74	73.353	Monodelphis_domestica
ENSG00000114416	FXR1	100	100.000	ENSMODG00000021294	FXR1	100	88.520	Monodelphis_domestica
ENSG00000114416	FXR1	100	74.667	ENSMODG00000007179	FXR2	100	55.184	Monodelphis_domestica
ENSG00000114416	FXR1	99	83.784	ENSMALG00000019947	fxr1	100	64.317	Monopterus_albus
ENSG00000114416	FXR1	100	70.732	ENSMALG00000003105	fxr2	99	60.702	Monopterus_albus
ENSG00000114416	FXR1	95	77.465	ENSMALG00000012587	fmr1	78	65.106	Monopterus_albus
ENSG00000114416	FXR1	100	100.000	MGP_CAROLIEiJ_G0024927	Fxr1	100	98.229	Mus_caroli
ENSG00000114416	FXR1	95	76.056	MGP_CAROLIEiJ_G0033121	Fmr1	75	73.952	Mus_caroli
ENSG00000114416	FXR1	100	76.000	MGP_CAROLIEiJ_G0016578	Fxr2	98	58.601	Mus_caroli
ENSG00000114416	FXR1	95	76.056	ENSMUSG00000000838	Fmr1	75	73.952	Mus_musculus
ENSG00000114416	FXR1	100	100.000	ENSMUSG00000027680	Fxr1	100	99.258	Mus_musculus
ENSG00000114416	FXR1	100	74.667	ENSMUSG00000018765	Fxr2	98	58.163	Mus_musculus
ENSG00000114416	FXR1	95	76.056	MGP_PahariEiJ_G0031663	Fmr1	75	73.952	Mus_pahari
ENSG00000114416	FXR1	100	100.000	MGP_PahariEiJ_G0026371	Fxr1	100	98.390	Mus_pahari
ENSG00000114416	FXR1	100	76.000	MGP_PahariEiJ_G0017709	Fxr2	98	58.163	Mus_pahari
ENSG00000114416	FXR1	100	100.000	MGP_SPRETEiJ_G0025861	Fxr1	100	98.229	Mus_spretus
ENSG00000114416	FXR1	100	74.667	MGP_SPRETEiJ_G0017414	Fxr2	98	58.017	Mus_spretus
ENSG00000114416	FXR1	95	76.056	MGP_SPRETEiJ_G0034275	Fmr1	75	73.952	Mus_spretus
ENSG00000114416	FXR1	100	76.000	ENSMPUG00000009051	FXR2	98	55.714	Mustela_putorius_furo
ENSG00000114416	FXR1	100	100.000	ENSMPUG00000002333	FXR1	100	95.525	Mustela_putorius_furo
ENSG00000114416	FXR1	95	77.465	ENSMPUG00000011485	FMR1	74	74.251	Mustela_putorius_furo
ENSG00000114416	FXR1	100	76.000	ENSMLUG00000003438	FXR2	99	58.900	Myotis_lucifugus
ENSG00000114416	FXR1	95	77.465	ENSMLUG00000000587	FMR1	72	74.551	Myotis_lucifugus
ENSG00000114416	FXR1	100	100.000	ENSMLUG00000006840	FXR1	100	91.074	Myotis_lucifugus
ENSG00000114416	FXR1	100	76.000	ENSNGAG00000016236	Fxr2	98	57.933	Nannospalax_galili
ENSG00000114416	FXR1	95	74.648	ENSNGAG00000020908	Fmr1	84	61.396	Nannospalax_galili
ENSG00000114416	FXR1	100	100.000	ENSNGAG00000021726	Fxr1	100	99.042	Nannospalax_galili
ENSG00000114416	FXR1	100	70.732	ENSNBRG00000012358	fxr2	100	55.745	Neolamprologus_brichardi
ENSG00000114416	FXR1	99	81.081	ENSNBRG00000021072	fxr1	94	68.912	Neolamprologus_brichardi
ENSG00000114416	FXR1	95	74.648	ENSNBRG00000022213	fmr1	88	65.368	Neolamprologus_brichardi
ENSG00000114416	FXR1	100	100.000	ENSNLEG00000005928	FXR1	100	100.000	Nomascus_leucogenys
ENSG00000114416	FXR1	95	77.465	ENSNLEG00000013269	FMR1	99	73.469	Nomascus_leucogenys
ENSG00000114416	FXR1	100	76.000	ENSNLEG00000009662	FXR2	98	56.672	Nomascus_leucogenys
ENSG00000114416	FXR1	100	93.617	ENSNLEG00000031391	-	95	82.812	Nomascus_leucogenys
ENSG00000114416	FXR1	60	74.242	ENSMEUG00000014280	-	61	74.242	Notamacropus_eugenii
ENSG00000114416	FXR1	100	100.000	ENSMEUG00000004706	FXR1	82	91.928	Notamacropus_eugenii
ENSG00000114416	FXR1	100	74.667	ENSOPRG00000017108	FXR2	94	58.089	Ochotona_princeps
ENSG00000114416	FXR1	100	100.000	ENSOPRG00000009223	FXR1	100	93.212	Ochotona_princeps
ENSG00000114416	FXR1	83	77.778	ENSODEG00000017803	FXR2	98	56.140	Octodon_degus
ENSG00000114416	FXR1	95	76.056	ENSODEG00000008377	FMR1	84	61.856	Octodon_degus
ENSG00000114416	FXR1	99	70.980	ENSODEG00000000998	-	100	65.120	Octodon_degus
ENSG00000114416	FXR1	100	99.194	ENSODEG00000001069	-	100	90.413	Octodon_degus
ENSG00000114416	FXR1	100	96.748	ENSODEG00000006177	-	91	96.735	Octodon_degus
ENSG00000114416	FXR1	100	70.732	ENSONIG00000018373	fxr2	100	55.887	Oreochromis_niloticus
ENSG00000114416	FXR1	95	76.056	ENSONIG00000015823	fmr1	78	64.957	Oreochromis_niloticus
ENSG00000114416	FXR1	99	79.730	ENSONIG00000003740	fxr1	100	66.069	Oreochromis_niloticus
ENSG00000114416	FXR1	98	97.991	ENSOANG00000011045	FXR1	99	94.393	Ornithorhynchus_anatinus
ENSG00000114416	FXR1	95	76.056	ENSOANG00000001097	FMR1	76	70.740	Ornithorhynchus_anatinus
ENSG00000114416	FXR1	100	74.667	ENSOANG00000005646	-	62	73.404	Ornithorhynchus_anatinus
ENSG00000114416	FXR1	95	77.465	ENSOCUG00000014621	FMR1	73	73.952	Oryctolagus_cuniculus
ENSG00000114416	FXR1	100	76.000	ENSOCUG00000010393	FXR2	99	56.994	Oryctolagus_cuniculus
ENSG00000114416	FXR1	100	100.000	ENSOCUG00000023518	FXR1	85	91.285	Oryctolagus_cuniculus
ENSG00000114416	FXR1	95	78.873	ENSORLG00000009094	fmr1	78	65.525	Oryzias_latipes
ENSG00000114416	FXR1	100	70.667	ENSORLG00000011571	fxr2	99	57.206	Oryzias_latipes
ENSG00000114416	FXR1	99	83.784	ENSORLG00000011787	fxr1	100	62.700	Oryzias_latipes
ENSG00000114416	FXR1	100	69.333	ENSORLG00020012552	fxr2	93	63.529	Oryzias_latipes_hni
ENSG00000114416	FXR1	99	83.784	ENSORLG00020005318	fxr1	100	65.000	Oryzias_latipes_hni
ENSG00000114416	FXR1	95	78.873	ENSORLG00020020254	fmr1	78	65.665	Oryzias_latipes_hni
ENSG00000114416	FXR1	100	70.667	ENSORLG00015013785	fxr2	99	57.206	Oryzias_latipes_hsok
ENSG00000114416	FXR1	99	83.784	ENSORLG00015003151	fxr1	100	65.000	Oryzias_latipes_hsok
ENSG00000114416	FXR1	95	78.873	ENSORLG00015015300	fmr1	78	65.525	Oryzias_latipes_hsok
ENSG00000114416	FXR1	95	78.873	ENSOMEG00000017281	fmr1	78	65.591	Oryzias_melastigma
ENSG00000114416	FXR1	99	83.784	ENSOMEG00000011753	fxr1	99	68.013	Oryzias_melastigma
ENSG00000114416	FXR1	100	69.333	ENSOMEG00000005986	fxr2	95	59.145	Oryzias_melastigma
ENSG00000114416	FXR1	100	76.000	ENSOGAG00000008146	FXR2	98	58.041	Otolemur_garnettii
ENSG00000114416	FXR1	100	100.000	ENSOGAG00000008751	FXR1	100	99.678	Otolemur_garnettii
ENSG00000114416	FXR1	95	76.056	ENSOGAG00000013061	FMR1	73	73.952	Otolemur_garnettii
ENSG00000114416	FXR1	100	76.000	ENSOARG00000014984	FXR2	98	57.372	Ovis_aries
ENSG00000114416	FXR1	100	100.000	ENSOARG00000020674	FXR1	100	99.357	Ovis_aries
ENSG00000114416	FXR1	95	77.465	ENSOARG00000009673	FMR1	72	73.952	Ovis_aries
ENSG00000114416	FXR1	99	61.484	ENSPPAG00000029387	FXR2	99	55.233	Pan_paniscus
ENSG00000114416	FXR1	100	100.000	ENSPPAG00000037630	-	100	100.000	Pan_paniscus
ENSG00000114416	FXR1	95	77.465	ENSPPAG00000041836	FMR1	99	74.150	Pan_paniscus
ENSG00000114416	FXR1	100	76.000	ENSPPRG00000009200	-	98	57.810	Panthera_pardus
ENSG00000114416	FXR1	100	100.000	ENSPPRG00000004943	FXR1	100	99.814	Panthera_pardus
ENSG00000114416	FXR1	100	62.602	ENSPPRG00000015847	-	96	65.267	Panthera_pardus
ENSG00000114416	FXR1	95	77.465	ENSPPRG00000018962	FMR1	72	74.251	Panthera_pardus
ENSG00000114416	FXR1	100	100.000	ENSPTIG00000019748	FXR1	100	99.814	Panthera_tigris_altaica
ENSG00000114416	FXR1	95	77.465	ENSPTIG00000019115	FMR1	84	67.478	Panthera_tigris_altaica
ENSG00000114416	FXR1	100	76.000	ENSPTIG00000007284	FXR2	93	56.176	Panthera_tigris_altaica
ENSG00000114416	FXR1	100	76.000	ENSPTRG00000008698	FXR2	98	57.810	Pan_troglodytes
ENSG00000114416	FXR1	95	77.465	ENSPTRG00000022349	FMR1	99	74.150	Pan_troglodytes
ENSG00000114416	FXR1	100	100.000	ENSPTRG00000015656	-	100	100.000	Pan_troglodytes
ENSG00000114416	FXR1	100	76.000	ENSPANG00000024057	FXR2	98	57.810	Papio_anubis
ENSG00000114416	FXR1	100	100.000	ENSPANG00000011899	FXR1	99	97.531	Papio_anubis
ENSG00000114416	FXR1	95	77.465	ENSPANG00000018447	FMR1	99	74.007	Papio_anubis
ENSG00000114416	FXR1	95	71.831	ENSPKIG00000001628	fmr1	79	66.157	Paramormyrops_kingsleyae
ENSG00000114416	FXR1	100	66.667	ENSPKIG00000014091	FXR1	99	60.494	Paramormyrops_kingsleyae
ENSG00000114416	FXR1	100	67.480	ENSPKIG00000025286	fxr2	99	58.185	Paramormyrops_kingsleyae
ENSG00000114416	FXR1	100	78.862	ENSPKIG00000002030	fxr1	99	70.382	Paramormyrops_kingsleyae
ENSG00000114416	FXR1	100	98.667	ENSPSIG00000007616	FXR1	97	83.969	Pelodiscus_sinensis
ENSG00000114416	FXR1	95	76.056	ENSPSIG00000009079	FMR1	81	66.372	Pelodiscus_sinensis
ENSG00000114416	FXR1	100	77.333	ENSPSIG00000008173	FXR2	97	60.217	Pelodiscus_sinensis
ENSG00000114416	FXR1	100	70.732	ENSPMGG00000005453	fxr2	87	57.118	Periophthalmus_magnuspinnatus
ENSG00000114416	FXR1	95	73.239	ENSPMGG00000013391	fmr1	80	71.693	Periophthalmus_magnuspinnatus
ENSG00000114416	FXR1	99	82.432	ENSPMGG00000014074	fxr1	97	72.998	Periophthalmus_magnuspinnatus
ENSG00000114416	FXR1	100	100.000	ENSPEMG00000012962	Fxr1	100	99.617	Peromyscus_maniculatus_bairdii
ENSG00000114416	FXR1	100	76.000	ENSPEMG00000019239	Fxr2	98	60.000	Peromyscus_maniculatus_bairdii
ENSG00000114416	FXR1	95	76.056	ENSPEMG00000017439	Fmr1	78	73.653	Peromyscus_maniculatus_bairdii
ENSG00000114416	FXR1	99	68.919	ENSPMAG00000007610	-	89	60.103	Petromyzon_marinus
ENSG00000114416	FXR1	95	76.056	ENSPMAG00000002849	-	99	53.859	Petromyzon_marinus
ENSG00000114416	FXR1	100	74.667	ENSPCIG00000028979	FXR2	98	58.150	Phascolarctos_cinereus
ENSG00000114416	FXR1	100	100.000	ENSPCIG00000026314	FXR1	100	96.790	Phascolarctos_cinereus
ENSG00000114416	FXR1	95	74.648	ENSPCIG00000022498	FMR1	77	73.353	Phascolarctos_cinereus
ENSG00000114416	FXR1	99	83.784	ENSPFOG00000014691	fxr1	97	65.861	Poecilia_formosa
ENSG00000114416	FXR1	100	70.667	ENSPFOG00000006858	fxr2	99	57.630	Poecilia_formosa
ENSG00000114416	FXR1	99	74.324	ENSPFOG00000004138	fmr1	77	64.392	Poecilia_formosa
ENSG00000114416	FXR1	100	70.667	ENSPLAG00000006074	fxr2	99	56.295	Poecilia_latipinna
ENSG00000114416	FXR1	99	83.784	ENSPLAG00000023193	fxr1	97	68.504	Poecilia_latipinna
ENSG00000114416	FXR1	99	74.324	ENSPLAG00000005126	fmr1	77	64.668	Poecilia_latipinna
ENSG00000114416	FXR1	99	74.324	ENSPMEG00000003164	fmr1	77	64.392	Poecilia_mexicana
ENSG00000114416	FXR1	99	83.784	ENSPMEG00000019092	fxr1	99	68.394	Poecilia_mexicana
ENSG00000114416	FXR1	100	70.667	ENSPMEG00000024257	fxr2	99	56.377	Poecilia_mexicana
ENSG00000114416	FXR1	100	69.333	ENSPREG00000002076	fxr2	99	57.481	Poecilia_reticulata
ENSG00000114416	FXR1	99	77.027	ENSPREG00000022738	fxr1	98	69.755	Poecilia_reticulata
ENSG00000114416	FXR1	99	72.973	ENSPREG00000003249	fmr1	78	70.561	Poecilia_reticulata
ENSG00000114416	FXR1	95	77.465	ENSPPYG00000020797	FMR1	85	62.028	Pongo_abelii
ENSG00000114416	FXR1	100	100.000	ENSPPYG00000014327	FXR1	100	100.000	Pongo_abelii
ENSG00000114416	FXR1	100	76.000	ENSPPYG00000007930	FXR2	92	54.367	Pongo_abelii
ENSG00000114416	FXR1	95	77.465	ENSPCAG00000011936	FMR1	74	74.251	Procavia_capensis
ENSG00000114416	FXR1	93	75.714	ENSPCAG00000013184	FXR2	98	59.717	Procavia_capensis
ENSG00000114416	FXR1	95	77.465	ENSPCOG00000028651	FMR1	99	74.830	Propithecus_coquereli
ENSG00000114416	FXR1	100	100.000	ENSPCOG00000020057	FXR1	100	95.169	Propithecus_coquereli
ENSG00000114416	FXR1	100	76.000	ENSPCOG00000024603	FXR2	98	57.749	Propithecus_coquereli
ENSG00000114416	FXR1	95	76.056	ENSPVAG00000013386	FMR1	72	73.952	Pteropus_vampyrus
ENSG00000114416	FXR1	100	100.000	ENSPVAG00000002823	FXR1	100	92.743	Pteropus_vampyrus
ENSG00000114416	FXR1	100	76.000	ENSPVAG00000016306	FXR2	92	58.735	Pteropus_vampyrus
ENSG00000114416	FXR1	95	74.648	ENSPNYG00000000045	fmr1	84	72.135	Pundamilia_nyererei
ENSG00000114416	FXR1	100	70.732	ENSPNYG00000018583	fxr2	100	55.887	Pundamilia_nyererei
ENSG00000114416	FXR1	99	81.081	ENSPNYG00000014047	fxr1	100	64.785	Pundamilia_nyererei
ENSG00000114416	FXR1	100	73.333	ENSPNAG00000013032	fxr2	99	56.765	Pygocentrus_nattereri
ENSG00000114416	FXR1	95	76.056	ENSPNAG00000006251	fmr1	80	67.325	Pygocentrus_nattereri
ENSG00000114416	FXR1	100	82.114	ENSPNAG00000021229	fxr1	94	70.000	Pygocentrus_nattereri
ENSG00000114416	FXR1	100	100.000	ENSRNOG00000051480	Fxr1	99	94.306	Rattus_norvegicus
ENSG00000114416	FXR1	95	76.056	ENSRNOG00000057464	Fmr1	75	73.952	Rattus_norvegicus
ENSG00000114416	FXR1	100	76.000	ENSRNOG00000011876	Fxr2	98	58.163	Rattus_norvegicus
ENSG00000114416	FXR1	100	100.000	ENSRBIG00000036968	FXR1	100	90.836	Rhinopithecus_bieti
ENSG00000114416	FXR1	100	76.000	ENSRBIG00000034647	FXR2	98	57.664	Rhinopithecus_bieti
ENSG00000114416	FXR1	79	51.860	ENSRBIG00000028998	FMR1	84	50.740	Rhinopithecus_bieti
ENSG00000114416	FXR1	100	100.000	ENSRROG00000034524	FXR1	100	100.000	Rhinopithecus_roxellana
ENSG00000114416	FXR1	95	77.465	ENSRROG00000044396	FMR1	99	72.632	Rhinopithecus_roxellana
ENSG00000114416	FXR1	100	76.000	ENSRROG00000035470	FXR2	98	57.664	Rhinopithecus_roxellana
ENSG00000114416	FXR1	99	74.324	ENSSBOG00000026623	FMR1	99	74.830	Saimiri_boliviensis_boliviensis
ENSG00000114416	FXR1	100	76.000	ENSSBOG00000031395	FXR2	100	57.478	Saimiri_boliviensis_boliviensis
ENSG00000114416	FXR1	100	100.000	ENSSBOG00000033567	FXR1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000114416	FXR1	100	74.667	ENSSHAG00000015678	FXR2	98	57.941	Sarcophilus_harrisii
ENSG00000114416	FXR1	95	74.648	ENSSHAG00000012940	FMR1	74	73.214	Sarcophilus_harrisii
ENSG00000114416	FXR1	100	100.000	ENSSHAG00000018625	FXR1	95	96.540	Sarcophilus_harrisii
ENSG00000114416	FXR1	99	87.838	ENSSFOG00015008103	fxr1	99	73.130	Scleropages_formosus
ENSG00000114416	FXR1	100	76.000	ENSSFOG00015013518	FXR1	77	67.754	Scleropages_formosus
ENSG00000114416	FXR1	95	76.056	ENSSFOG00015004051	fmr1	81	67.686	Scleropages_formosus
ENSG00000114416	FXR1	100	69.106	ENSSFOG00015016623	fxr2	97	64.211	Scleropages_formosus
ENSG00000114416	FXR1	100	69.333	ENSSMAG00000013659	fxr2	100	54.455	Scophthalmus_maximus
ENSG00000114416	FXR1	99	83.784	ENSSMAG00000019240	fxr1	96	70.420	Scophthalmus_maximus
ENSG00000114416	FXR1	95	74.648	ENSSMAG00000013698	fmr1	75	70.619	Scophthalmus_maximus
ENSG00000114416	FXR1	99	82.432	ENSSDUG00000016557	fxr1	100	65.625	Seriola_dumerili
ENSG00000114416	FXR1	100	69.333	ENSSDUG00000018392	fxr2	100	55.304	Seriola_dumerili
ENSG00000114416	FXR1	95	76.056	ENSSDUG00000013947	fmr1	84	62.708	Seriola_dumerili
ENSG00000114416	FXR1	95	76.056	ENSSLDG00000022042	fmr1	79	69.129	Seriola_lalandi_dorsalis
ENSG00000114416	FXR1	99	82.432	ENSSLDG00000018386	fxr1	98	71.986	Seriola_lalandi_dorsalis
ENSG00000114416	FXR1	100	69.333	ENSSLDG00000017119	fxr2	100	55.163	Seriola_lalandi_dorsalis
ENSG00000114416	FXR1	100	100.000	ENSSARG00000011976	FXR1	89	97.386	Sorex_araneus
ENSG00000114416	FXR1	100	74.667	ENSSARG00000006113	FXR2	92	50.830	Sorex_araneus
ENSG00000114416	FXR1	95	77.465	ENSSARG00000003475	FMR1	70	74.359	Sorex_araneus
ENSG00000114416	FXR1	99	97.333	ENSSPUG00000014501	FXR1	100	97.333	Sphenodon_punctatus
ENSG00000114416	FXR1	95	76.056	ENSSPUG00000014177	FMR1	84	67.342	Sphenodon_punctatus
ENSG00000114416	FXR1	100	69.106	ENSSPAG00000007975	fxr2	96	60.035	Stegastes_partitus
ENSG00000114416	FXR1	99	83.784	ENSSPAG00000010538	fxr1	99	68.174	Stegastes_partitus
ENSG00000114416	FXR1	95	76.056	ENSSPAG00000005758	fmr1	77	64.468	Stegastes_partitus
ENSG00000114416	FXR1	100	100.000	ENSSSCG00000011769	FXR1	100	99.629	Sus_scrofa
ENSG00000114416	FXR1	100	76.000	ENSSSCG00000017953	FXR2	99	58.248	Sus_scrofa
ENSG00000114416	FXR1	95	77.465	ENSSSCG00000012727	FMR1	88	63.232	Sus_scrofa
ENSG00000114416	FXR1	95	76.056	ENSTGUG00000004735	FMR1	85	60.941	Taeniopygia_guttata
ENSG00000114416	FXR1	100	97.333	ENSTGUG00000010560	FXR1	100	84.697	Taeniopygia_guttata
ENSG00000114416	FXR1	100	65.041	ENSTRUG00000010696	fxr2	93	55.452	Takifugu_rubripes
ENSG00000114416	FXR1	99	74.324	ENSTRUG00000003486	fxr1	100	61.976	Takifugu_rubripes
ENSG00000114416	FXR1	95	71.831	ENSTRUG00000005362	fmr1	80	58.952	Takifugu_rubripes
ENSG00000114416	FXR1	99	77.027	ENSTNIG00000003790	fxr1	100	61.061	Tetraodon_nigroviridis
ENSG00000114416	FXR1	95	73.239	ENSTNIG00000010121	fmr1	80	62.000	Tetraodon_nigroviridis
ENSG00000114416	FXR1	100	66.667	ENSTNIG00000005118	fxr2	99	59.541	Tetraodon_nigroviridis
ENSG00000114416	FXR1	100	76.000	ENSTBEG00000002514	FXR2	94	54.071	Tupaia_belangeri
ENSG00000114416	FXR1	95	74.648	ENSTBEG00000003253	FMR1	60	71.429	Tupaia_belangeri
ENSG00000114416	FXR1	65	100.000	ENSTBEG00000007370	-	65	100.000	Tupaia_belangeri
ENSG00000114416	FXR1	95	77.465	ENSTTRG00000000613	FMR1	73	72.910	Tursiops_truncatus
ENSG00000114416	FXR1	100	76.000	ENSTTRG00000010231	FXR2	92	58.522	Tursiops_truncatus
ENSG00000114416	FXR1	100	100.000	ENSTTRG00000014698	FXR1	100	99.356	Tursiops_truncatus
ENSG00000114416	FXR1	99	74.324	ENSUAMG00000013787	FMR1	95	73.118	Ursus_americanus
ENSG00000114416	FXR1	100	76.000	ENSUAMG00000001330	FXR2	98	58.419	Ursus_americanus
ENSG00000114416	FXR1	100	100.000	ENSUAMG00000006833	FXR1	100	99.627	Ursus_americanus
ENSG00000114416	FXR1	100	100.000	ENSUMAG00000007061	FXR1	100	99.627	Ursus_maritimus
ENSG00000114416	FXR1	95	77.465	ENSUMAG00000009869	FMR1	98	70.588	Ursus_maritimus
ENSG00000114416	FXR1	100	76.000	ENSUMAG00000016725	FXR2	100	55.058	Ursus_maritimus
ENSG00000114416	FXR1	100	100.000	ENSVPAG00000003384	FXR1	100	99.503	Vicugna_pacos
ENSG00000114416	FXR1	95	77.465	ENSVPAG00000008700	FMR1	71	74.051	Vicugna_pacos
ENSG00000114416	FXR1	100	76.000	ENSVPAG00000000147	FXR2	86	66.667	Vicugna_pacos
ENSG00000114416	FXR1	100	100.000	ENSVVUG00000006660	FXR1	100	99.678	Vulpes_vulpes
ENSG00000114416	FXR1	95	77.465	ENSVVUG00000000753	FMR1	70	73.333	Vulpes_vulpes
ENSG00000114416	FXR1	100	76.000	ENSVVUG00000027916	FXR2	73	58.248	Vulpes_vulpes
ENSG00000114416	FXR1	95	76.056	ENSXETG00000019647	fmr1	82	68.615	Xenopus_tropicalis
ENSG00000114416	FXR1	100	85.366	ENSXETG00000019441	fxr1	100	84.154	Xenopus_tropicalis
ENSG00000114416	FXR1	100	69.333	ENSXCOG00000005798	fxr2	93	73.214	Xiphophorus_couchianus
ENSG00000114416	FXR1	99	61.111	ENSXCOG00000008158	fxr1	95	59.768	Xiphophorus_couchianus
ENSG00000114416	FXR1	99	74.324	ENSXCOG00000013342	fmr1	90	65.727	Xiphophorus_couchianus
ENSG00000114416	FXR1	99	74.324	ENSXMAG00000000827	fmr1	78	64.668	Xiphophorus_maculatus
ENSG00000114416	FXR1	100	69.333	ENSXMAG00000011669	fxr2	99	56.769	Xiphophorus_maculatus
ENSG00000114416	FXR1	99	83.784	ENSXMAG00000000666	fxr1	100	66.265	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0005515	protein binding	7489725.11157796.15380484.16571602.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005730	nucleolus	10888599.	TAS	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005844	polysome	21873635.	IBA	Component
GO:0006915	apoptotic process	9642279.	TAS	Process
GO:0007517	muscle organ development	-	IEA	Process
GO:0014069	postsynaptic density	21873635.	IBA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0017148	negative regulation of translation	21873635.	IBA	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0030424	axon	21873635.	IBA	Component
GO:0033592	RNA strand annealing activity	17057366.	IDA	Function
GO:0035770	ribonucleoprotein granule	21873635.	IBA	Component
GO:0036464	cytoplasmic ribonucleoprotein granule	21873635.	IBA	Component
GO:0042803	protein homodimerization activity	21873635.	IBA	Function
GO:0042803	protein homodimerization activity	7489725.	IDA	Function
GO:0043025	neuronal cell body	21873635.	IBA	Component
GO:0043034	costamere	-	IEA	Component
GO:0043197	dendritic spine	21873635.	IBA	Component
GO:0043488	regulation of mRNA stability	21873635.	IBA	Process
GO:0045182	translation regulator activity	21873635.	IBA	Function
GO:0045727	positive regulation of translation	21873635.	IBA	Process
GO:0046982	protein heterodimerization activity	7489725.	IDA	Function
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component
GO:0098978	glutamatergic synapse	-	IEA	Component
GO:2000637	positive regulation of gene silencing by miRNA	17057366.	IDA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.