EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr3	42659502	Missense_Mutation	novel	E383K	0.3
BLCA	chr3	42661587	Missense_Mutation	novel	E526Q	0.16
BLCA	chr3	42663102	Missense_Mutation	novel	S571L	0.26
BLCA	chr3	42661495	Missense_Mutation	NA	C495Y	0.42
BLCA	chr3	42663905	Missense_Mutation	novel	K616E	0.2
BLCA	chr3	42663796	Splice_Site	novel	X580_splice	0.24
BRCA	chr3	42665308	3'UTR	novel		0.17
BRCA	chr3	42658499	Missense_Mutation	NA	Q48H	0.45
CESC	chr3	42659400	Nonsense_Mutation	NA	E349*	0.45
CESC	chr3	42658956	Missense_Mutation	rs775482924	G201S	0.46
CESC	chr3	42658568	Silent	novel	L71L	0.1
CESC	chr3	42663809	Missense_Mutation	NA	R584C	0.25
CESC	chr3	42665761	3'UTR	novel		0.35
CESC	chr3	42659174	Missense_Mutation	NA	Q273H	0.5
CESC	chr3	42659672	Missense_Mutation	NA	Q439H	0.53
CESC	chr3	42666868	3'Flank	novel		0.21
CESC	chr3	42661530	Nonsense_Mutation	novel	E507*	0.33
CESC	chr3	42659602	Missense_Mutation	novel	R416P	0.43
COAD	chr3	42663058	Silent	NA	S556S	0.38
COAD	chr3	42664244	Silent	novel	K630K	0.34
COAD	chr3	42661614	Missense_Mutation	novel	V535M	0.28
COAD	chr3	42659737	Missense_Mutation	rs748657390	R461H	0.19
ESCA	chr3	42665774	3'UTR	novel		0.24
ESCA	chr3	42659829	Splice_Site	novel	X491_splice	0.15
ESCA	chr3	42666319	3'Flank	novel		0.59
GBM	chr3	42661556	Silent	rs377289828	Y515Y	0.25
HNSC	chr3	42661552	Missense_Mutation	novel	G514D	0.24
LGG	chr3	42659558	Silent	novel	G401G	0.36
LUAD	chr3	42659690	Silent	novel	F445F	0.09
LUAD	chr3	42661609	Missense_Mutation	NA	A533V	0.34
LUAD	chr3	42664244	Missense_Mutation	novel	K630N	0.11
LUAD	chr3	42659793	Silent	novel	L480L	0.73
LUSC	chr3	42661611	Missense_Mutation	NA	H534Y	0.27
OV	chr3	42663830	Missense_Mutation	NA	L591V	0.42
OV	chr3	42661497	Missense_Mutation	novel	G496S	0.11
PAAD	chr3	42661608	Missense_Mutation	novel	A533T	0.08
PAAD	chr3	42663916	Silent	novel	F619F	0.23
PRAD	chr3	42663115	Silent	rs374607271	P575P	0.04
SARC	chr3	42666055	3'Flank	novel		0.43
SKCM	chr3	42659456	Silent	novel	S367S	0.58
SKCM	chr3	42663850	Silent	NA	I597I	0.34
STAD	chr3	42664390	In_Frame_Del	novel	E680del	0.55
STAD	chr3	42663917	Missense_Mutation	novel	D620N	0.26
STAD	chr3	42664340	Silent	rs539367074	C662C	0.38
STAD	chr3	42661578	Missense_Mutation	rs778441568	E523K	0.34
STAD	chr3	42659546	Silent	NA	G397G	0.26
STAD	chr3	42659574	Frame_Shift_Del	NA	*P408Lfs21**	0.27
STAD	chr3	42659794	Missense_Mutation	NA	L480Q	0.18
THYM	chr3	42658650	Missense_Mutation	novel	A99S	0.13
UCEC	chr3	42663049	Silent	rs775708314	C553C	0.27
UCEC	chr3	42658664	Silent	novel	A103A	0.1
UCEC	chr3	42661617	Missense_Mutation	rs746811113	R536C	0.09
UCEC	chr3	42664357	Missense_Mutation	novel	R668H	0.24
UCEC	chr3	42658316	5'UTR	novel		0.48
UCEC	chr3	42663895	Missense_Mutation	novel	D612E	0.08
UCEC	chr3	42658689	Missense_Mutation	novel	R112C	0.51
UCEC	chr3	42663807	Missense_Mutation	novel	E583G	0.05
UCEC	chr3	42658400	Silent	rs746083944	C15C	0.34
UCEC	chr3	42666952	3'Flank	novel		0.45
UCEC	chr3	42663808	Missense_Mutation	NA	E583D	0.23
UCEC	chr3	42658663	Missense_Mutation	novel	A103V	0.24
UCEC	chr3	42658509	Silent	NA	L52L	0.63
UCEC	chr3	42663833	Missense_Mutation	novel	R592W	0.47
UCEC	chr3	42666377	3'Flank	novel		0.23
UCEC	chr3	42659742	Missense_Mutation	novel	Q463K	0.26
UCEC	chr3	42666030	3'Flank	novel		0.26
UCEC	chr3	42659766	Missense_Mutation	NA	R471C	0.22
UCEC	chr3	42659817	Missense_Mutation	rs766624757	R488C	0.39
UCEC	chr3	42658628	Silent	rs761571204	S91S	0.13
UCEC	chr3	42658814	Missense_Mutation	novel	K153N	0.42
UCEC	chr3	42661617	Missense_Mutation	rs746811113	R536C	0.53
UCEC	chr3	42665870	3'Flank	novel		0.36
UCEC	chr3	42665992	3'Flank	novel		0.11
UCEC	chr3	42658601	Silent	rs532702617	N82N	0.25
UCEC	chr3	42658404	Missense_Mutation	novel	V17M	0.6
UCEC	chr3	42666853	3'Flank	novel		0.29
UCEC	chr3	42659704	Missense_Mutation	novel	Y450C	0.32
UCEC	chr3	42659724	Missense_Mutation	NA	V457M	0.48
UCEC	chr3	42666952	3'Flank	novel		0.24
UCEC	chr3	42666380	3'Flank	novel		0.41
UCEC	chr3	42659601	Nonsense_Mutation	novel	R416*	0.4
UCEC	chr3	42658403	Silent	novel	D16D	0.45
UCEC	chr3	42666116	3'Flank	novel		0.53
UCEC	chr3	42659770	Missense_Mutation	novel	F472Y	0.17
UCEC	chr3	42658395	Missense_Mutation	novel	L14I	0.23
UCEC	chr3	42659759	Silent	rs770741364	C468C	0.33
UCEC	chr3	42663028	Missense_Mutation	rs773137165	M546I	0.36
UCEC	chr3	42664330	Missense_Mutation	NA	P659L	0.5
UCEC	chr3	42664284	Missense_Mutation	NA	R644W	0.18	zf-C2H2
UCEC	chr3	42666042	3'Flank	novel		0.35
UCEC	chr3	42666731	3'Flank	novel		0.42
UCEC	chr3	42658404	Missense_Mutation	novel	V17M	0.32
UCEC	chr3	42659202	Missense_Mutation	novel	D283N	0.32
UCEC	chr3	42663916	Silent	novel	F619F	0.46
UCEC	chr3	42658890	Missense_Mutation	novel	P179S	0.35
UCEC	chr3	42666357	3'Flank	novel		0.36
UCEC	chr3	42658306	5'UTR	novel		0.35
UCEC	chr3	42659683	Missense_Mutation	novel	R443Q	0.45
UCEC	chr3	42661571	Missense_Mutation	NA	F520L	0.32
UCEC	chr3	42665529	3'UTR	novel		0.29
UCEC	chr3	42666359	3'Flank	novel		0.42
UCEC	chr3	42658686	Missense_Mutation	novel	A111T	0.41
UCEC	chr3	42664245	Missense_Mutation	novel	P631S	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.7778	0.02241
DLBC	DEL	0.1458	0.016959
GBM	DEL	0.0745	0.056565
PAAD	DEL	0.1685	0.030662
SKCM	DEL	0.1499	0.13887
TGCT	DEL	0.2	0.08422
THYM	DEL	0.0894	0.037527

Survival Analysis

Cancer	P-value	Q-value
SARC	0.018	Kaplan-Meier Survival Analysis
MESO	0.0057	Kaplan-Meier Survival Analysis
HNSC	0.043	Kaplan-Meier Survival Analysis
LUSC	0.01	Kaplan-Meier Survival Analysis
ESCA	0.018	Kaplan-Meier Survival Analysis
CESC	0.023	Kaplan-Meier Survival Analysis
LAML	0.015	Kaplan-Meier Survival Analysis
UCEC	0.012	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
UVM	0.00012	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000114853 (Gene tree)
Gene ID: 92999
Gene Symbol: ZBTB47
Alias: KIAA1190|DKFZp434N0615|ZNF651
Full Name: zinc finger and BTB domain containing 47
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 13,897 bases
Position: chr3:42,653,684-42,667,580
Accession: 26955
RBP type: canonical RBP
Summary: ZBTB47 (Zinc Finger And BTB Domain Containing 47) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF652.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000232974	zf-C2H2	PF00096.26	8.1e-31	1	4
ENSP00000232974	zf-C2H2	PF00096.26	8.1e-31	2	4
ENSP00000232974	zf-C2H2	PF00096.26	8.1e-31	3	4
ENSP00000232974	zf-C2H2	PF00096.26	8.1e-31	4	4
ENSP00000420968	zf-C2H2	PF00096.26	9.8e-29	1	4
ENSP00000420968	zf-C2H2	PF00096.26	9.8e-29	2	4
ENSP00000420968	zf-C2H2	PF00096.26	9.8e-29	3	4
ENSP00000420968	zf-C2H2	PF00096.26	9.8e-29	4	4
ENSP00000420968	zf-met	PF12874.7	4.9e-11	1	2
ENSP00000420968	zf-met	PF12874.7	4.9e-11	2	2
ENSP00000232974	zf-met	PF12874.7	3.1e-08	1	2
ENSP00000232974	zf-met	PF12874.7	3.1e-08	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000232974	ZBTB47-201	3781	-	ENSP00000232974	747 (aa)	-	Q9UFB7
ENST00000505904	ZBTB47-202	2456	-	ENSP00000420968	293 (aa)	-	D6RDG5

Gene Model

Click here to download ENSG00000114853's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000114853's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000114853	ZBTB47	100	87.713	ENSAMEG00000012484	ZBTB47	100	82.909	Ailuropoda_melanoleuca
ENSG00000114853	ZBTB47	100	75.701	ENSACIG00000020938	zbtb47b	81	88.077	Amphilophus_citrinellus
ENSG00000114853	ZBTB47	93	95.839	ENSANAG00000037099	ZBTB47	96	95.839	Aotus_nancymaae
ENSG00000114853	ZBTB47	88	82.759	ENSAMXG00000042191	zbtb47a	76	90.254	Astyanax_mexicanus
ENSG00000114853	ZBTB47	76	100.000	ENSBTAG00000017365	ZBTB47	84	95.636	Bos_taurus
ENSG00000114853	ZBTB47	82	97.490	ENSCJAG00000038339	ZBTB47	50	92.506	Callithrix_jacchus
ENSG00000114853	ZBTB47	100	92.542	ENSCAFG00000030889	ZBTB47	63	94.182	Canis_familiaris
ENSG00000114853	ZBTB47	100	92.542	ENSCAFG00020025264	ZBTB47	50	92.308	Canis_lupus_dingo
ENSG00000114853	ZBTB47	89	86.063	ENSTSYG00000029574	ZBTB47	94	89.137	Carlito_syrichta
ENSG00000114853	ZBTB47	93	95.960	ENSCCAG00000036182	ZBTB47	95	95.487	Cebus_capucinus
ENSG00000114853	ZBTB47	100	98.294	ENSCATG00000033756	ZBTB47	100	98.128	Cercocebus_atys
ENSG00000114853	ZBTB47	100	98.294	ENSCSAG00000016763	ZBTB47	100	98.128	Chlorocebus_sabaeus
ENSG00000114853	ZBTB47	86	92.913	ENSCPBG00000004296	ZBTB47	77	92.661	Chrysemys_picta_bellii
ENSG00000114853	ZBTB47	100	98.398	ENSCANG00000032693	ZBTB47	100	98.398	Colobus_angolensis_palliatus
ENSG00000114853	ZBTB47	94	77.739	ENSCSEG00000017606	zbtb47b	95	72.876	Cynoglossus_semilaevis
ENSG00000114853	ZBTB47	98	80.399	ENSDARG00000079547	zbtb47b	99	94.717	Danio_rerio
ENSG00000114853	ZBTB47	96	77.972	ENSDARG00000057751	zbtb47a	92	83.077	Danio_rerio
ENSG00000114853	ZBTB47	84	78.138	ENSETEG00000013682	-	99	71.212	Echinops_telfairi
ENSG00000114853	ZBTB47	85	64.113	ENSEBUG00000011263	zbtb47b	63	60.252	Eptatretus_burgeri
ENSG00000114853	ZBTB47	86	97.628	ENSEASG00005007917	ZBTB47	50	94.057	Equus_asinus_asinus
ENSG00000114853	ZBTB47	86	98.024	ENSECAG00000020244	ZBTB47	52	94.057	Equus_caballus
ENSG00000114853	ZBTB47	100	96.928	ENSFCAG00000000532	ZBTB47	100	96.928	Felis_catus
ENSG00000114853	ZBTB47	92	69.097	ENSFDAG00000019359	-	96	72.202	Fukomys_damarensis
ENSG00000114853	ZBTB47	81	96.639	ENSGALG00000005287	ZBTB47	86	93.173	Gallus_gallus
ENSG00000114853	ZBTB47	100	82.594	ENSGAFG00000005321	zbtb47b	96	85.985	Gambusia_affinis
ENSG00000114853	ZBTB47	89	85.660	ENSGACG00000003372	zbtb47b	91	79.635	Gasterosteus_aculeatus
ENSG00000114853	ZBTB47	100	100.000	ENSGGOG00000000433	ZBTB47	100	99.599	Gorilla_gorilla
ENSG00000114853	ZBTB47	83	95.455	ENSHGLG00100019142	ZBTB47	50	87.216	Heterocephalus_glaber_male
ENSG00000114853	ZBTB47	93	84.926	ENSIPUG00000011399	zbtb47b	91	85.393	Ictalurus_punctatus
ENSG00000114853	ZBTB47	78	90.000	ENSIPUG00000003040	zbtb47a	82	90.000	Ictalurus_punctatus
ENSG00000114853	ZBTB47	96	82.500	ENSKMAG00000010330	zbtb47b	80	91.209	Kryptolebias_marmoratus
ENSG00000114853	ZBTB47	100	74.923	ENSLBEG00000019067	zbtb47b	80	94.581	Labrus_bergylta
ENSG00000114853	ZBTB47	94	86.926	ENSLAFG00000003570	ZBTB47	86	92.308	Loxodonta_africana
ENSG00000114853	ZBTB47	100	98.529	ENSMFAG00000042184	ZBTB47	100	98.529	Macaca_fascicularis
ENSG00000114853	ZBTB47	100	98.529	ENSMMUG00000021243	ZBTB47	100	98.529	Macaca_mulatta
ENSG00000114853	ZBTB47	100	98.529	ENSMNEG00000027370	ZBTB47	100	98.529	Macaca_nemestrina
ENSG00000114853	ZBTB47	100	98.529	ENSMLEG00000042601	ZBTB47	100	98.529	Mandrillus_leucophaeus
ENSG00000114853	ZBTB47	100	74.303	ENSMAMG00000001808	zbtb47b	75	91.632	Mastacembelus_armatus
ENSG00000114853	ZBTB47	81	96.218	ENSMGAG00000002353	ZBTB47	85	83.284	Meleagris_gallopavo
ENSG00000114853	ZBTB47	100	97.270	ENSMICG00000049526	ZBTB47	100	90.897	Microcebus_murinus
ENSG00000114853	ZBTB47	91	89.513	ENSMODG00000013582	ZBTB47	99	78.400	Monodelphis_domestica
ENSG00000114853	ZBTB47	100	73.846	ENSMALG00000006454	zbtb47b	97	88.189	Monopterus_albus
ENSG00000114853	ZBTB47	100	94.881	ENSMPUG00000011833	ZBTB47	50	92.765	Mustela_putorius_furo
ENSG00000114853	ZBTB47	78	93.913	ENSMLUG00000001613	ZBTB47	93	91.573	Myotis_lucifugus
ENSG00000114853	ZBTB47	100	75.466	ENSNBRG00000018718	zbtb47b	79	89.764	Neolamprologus_brichardi
ENSG00000114853	ZBTB47	82	97.083	ENSMEUG00000013550	-	58	96.727	Notamacropus_eugenii
ENSG00000114853	ZBTB47	89	91.538	ENSOPRG00000016005	ZBTB47	99	91.636	Ochotona_princeps
ENSG00000114853	ZBTB47	97	81.724	ENSONIG00000005797	zbtb47b	73	85.149	Oreochromis_niloticus
ENSG00000114853	ZBTB47	71	96.172	ENSOANG00000010793	-	88	93.151	Ornithorhynchus_anatinus
ENSG00000114853	ZBTB47	80	99.574	ENSOCUG00000020899	ZBTB47	97	93.921	Oryctolagus_cuniculus
ENSG00000114853	ZBTB47	100	99.659	ENSPPAG00000028513	ZBTB47	100	99.199	Pan_paniscus
ENSG00000114853	ZBTB47	75	93.665	ENSPTIG00000013306	-	92	93.665	Panthera_tigris_altaica
ENSG00000114853	ZBTB47	100	99.659	ENSPTRG00000014798	ZBTB47	100	99.065	Pan_troglodytes
ENSG00000114853	ZBTB47	100	98.396	ENSPANG00000008922	ZBTB47	100	98.396	Papio_anubis
ENSG00000114853	ZBTB47	100	84.642	ENSPSIG00000018010	ZBTB47	50	80.223	Pelodiscus_sinensis
ENSG00000114853	ZBTB47	93	83.516	ENSPMGG00000023652	zbtb47b	74	87.633	Periophthalmus_magnuspinnatus
ENSG00000114853	ZBTB47	78	69.264	ENSPMAG00000006198	ZBTB47	70	67.068	Petromyzon_marinus
ENSG00000114853	ZBTB47	78	71.304	ENSPMAG00000007050	ZBTB47	92	64.214	Petromyzon_marinus
ENSG00000114853	ZBTB47	100	76.543	ENSPFOG00000004330	zbtb47b	53	69.036	Poecilia_formosa
ENSG00000114853	ZBTB47	100	82.253	ENSPLAG00000007917	zbtb47b	96	85.660	Poecilia_latipinna
ENSG00000114853	ZBTB47	100	82.594	ENSPMEG00000005793	zbtb47b	96	83.883	Poecilia_mexicana
ENSG00000114853	ZBTB47	85	75.269	ENSPREG00000020897	zbtb47b	58	80.579	Poecilia_reticulata
ENSG00000114853	ZBTB47	100	99.317	ENSPPYG00000029781	-	100	99.191	Pongo_abelii
ENSG00000114853	ZBTB47	100	96.928	ENSPCOG00000026676	ZBTB47	100	92.236	Propithecus_coquereli
ENSG00000114853	ZBTB47	85	80.784	ENSPNYG00000004668	zbtb47b	64	94.118	Pundamilia_nyererei
ENSG00000114853	ZBTB47	94	79.137	ENSPNAG00000004318	zbtb47a	85	84.314	Pygocentrus_nattereri
ENSG00000114853	ZBTB47	100	97.952	ENSRBIG00000036706	-	100	97.952	Rhinopithecus_bieti
ENSG00000114853	ZBTB47	100	98.396	ENSRROG00000030327	ZBTB47	100	98.396	Rhinopithecus_roxellana
ENSG00000114853	ZBTB47	92	96.517	ENSSBOG00000020906	ZBTB47	100	96.517	Saimiri_boliviensis_boliviensis
ENSG00000114853	ZBTB47	84	94.378	ENSSHAG00000007698	ZBTB47	88	87.960	Sarcophilus_harrisii
ENSG00000114853	ZBTB47	100	75.389	ENSSLDG00000014177	zbtb47b	74	93.724	Seriola_lalandi_dorsalis
ENSG00000114853	ZBTB47	51	88.732	ENSTGUG00000000271	-	62	88.732	Taeniopygia_guttata
ENSG00000114853	ZBTB47	89	79.693	ENSTGUG00000000272	ZBTB47	89	77.814	Taeniopygia_guttata
ENSG00000114853	ZBTB47	97	80.345	ENSTNIG00000001401	zbtb47b	79	84.053	Tetraodon_nigroviridis
ENSG00000114853	ZBTB47	100	77.816	ENSTTRG00000009725	ZBTB47	96	95.636	Tursiops_truncatus
ENSG00000114853	ZBTB47	100	95.222	ENSUAMG00000008413	ZBTB47	51	89.922	Ursus_americanus
ENSG00000114853	ZBTB47	100	87.031	ENSVVUG00000005205	ZBTB47	50	86.889	Vulpes_vulpes
ENSG00000114853	ZBTB47	100	81.973	ENSXETG00000006162	zbtb47	93	77.946	Xenopus_tropicalis
ENSG00000114853	ZBTB47	100	81.911	ENSXCOG00000009992	zbtb47b	88	89.200	Xiphophorus_couchianus
ENSG00000114853	ZBTB47	76	94.350	ENSXMAG00000009463	zbtb47b	94	81.781	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0006974	cellular response to DNA damage stimulus	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.