EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
18953434	Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer.	Neoplasia	2008 Nov	Gorringe KL	-
17289567	CHD5 is a tumor suppressor at human 1p36.	Cell	2007 Feb 9	Bagchi A	-
19840376	CHD5 is down-regulated through promoter hypermethylation in gastric cancer.	J Biomed Sci	2009 Oct 19	Wang X	doi: 10.1186/1423-0127-16-95.
22186629	CHD5, a tumor suppressor that is epigenetically silenced in lung cancer.	Lung Cancer	2012 Jun	Zhao R	doi: 10.1016/j.lungcan.2011.11.019
24923445	The tumor suppressor chromodomain helicase DNA-binding protein 5 (CHD5) remodels nucleosomes by unwrapping.	J Biol Chem	2014 Jul 25	Quan J	-
18698156	Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer.	Epigenetics	2008 Jul-Aug	Mulero-Navarro S	-
23948251	CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression.	Dev Cell	2013 Aug 12	Egan CM	doi: 10.1016/j.devcel.2013.07.008.
22910690	Analysis of common variations in tumor-suppressor genes on chr1p36 among Caucasian women with endometriosis.	Gynecol Oncol	2012 Nov	Falconer H	doi: 10.1016/j.ygyno.2012.08.013
23707602	Downregulation of chromatin remodeling factor CHD5 is associated with a poor prognosis in human glioma.	J Clin Neurosci	2013 Jul	Wang L	doi: 10.1016/j.jocn.2012.07.021
24243398	Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages.	Cancer	2014 Jan 15	Fatemi M	doi: 10.1002/cncr.28316
21636313	The involvement of CHD5 hypermethylation in laryngeal squamous cell carcinoma.	Oral Oncol	2011 Jul	Wang J	doi: 10.1016/j.oraloncology.2011.05.003
25247294	The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.	PLoS One	2014 Sep 23	Quan J	doi: 10.1371/journal.pone.0108066
18413720	The quest for the 1p36 tumor suppressor.	Cancer Res	2008 Apr 15	Bagchi A	doi: 10.1158/0008-5472.CAN-07-2095.
18577749	CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas.	J Natl Cancer Inst	2008 Jul 2	Fujita T	doi: 10.1093/jnci/djn176
28400267	CHD5 is a potential tumor suppressor in non small cell lung cancer (NSCLC).	Gene	2017 Jun 30	Baykara O	doi: 10.1016/j.gene.2017.04.010
26943038	The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation.	Oncotarget	2016 Apr 19	Du Z	doi: 10.18632/oncotarget.7822.
22569290	Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancer.	Breast Cancer Res	2012 May 8	Wu X	-
21860208	CHD5 Downregulation Associated with Poor Prognosis in Epithelial Ovarian Cancer.	Gynecol Obstet Invest	2011	Wong RR	doi: 10.1159/000323883
26753653	Influence of colorectal cancer tumor suppressor gene CHD5 methylation on its clinical and pathological characteristics.	J Biol Regul Homeost Agents	2015 Oct-Dec	Liu JB	-
24276239	Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.	Oncogene	2014 Nov 20	Hall WA	doi: 10.1038/onc.2013.488

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr1	6130157	Intron	novel		0.21
ACC	chr1	6136796	Silent	novel	L836L	0.24
ACC	chr1	6144098	Missense_Mutation	novel	D620E	0.03
BLCA	chr1	6129050	Missense_Mutation	NA	R1136H	0.22
BLCA	chr1	6109937	Silent	novel	L1812L	0.22
BLCA	chr1	6142190	Missense_Mutation	novel	E792Q	0.32	ResIII
BLCA	chr1	6136838	Silent	novel	L822L	0.18
BLCA	chr1	6155611	Missense_Mutation	novel	S165N	0.38
BLCA	chr1	6109929	Missense_Mutation	rs573215215	T1815M	0.62
BLCA	chr1	6121174	Missense_Mutation	novel	E1615K	0.26
BLCA	chr1	6154846	Missense_Mutation	NA	V187I	0.62
BLCA	chr1	6129040	Silent	NA	Q1139Q	0.4
BLCA	chr1	6148869	Silent	novel	L456L	0.09
BLCA	chr1	6113000	Splice_Site	novel	X1638_splice	0.31
BLCA	chr1	6121534	Missense_Mutation	novel	D1580V	0.41
BLCA	chr1	6124081	Silent	novel	G1522G	0.39
BLCA	chr1	6142232	Missense_Mutation	novel	V778I	0.22	ResIII
BLCA	chr1	6142455	Missense_Mutation	novel	T732A	0.33	ResIII
BLCA	chr1	6146263	Missense_Mutation	rs141210110	R584H	0.24
BLCA	chr1	6125826	Missense_Mutation	novel	E1371K	0.55
BLCA	chr1	6112999	Splice_Site	NA	X1638_splice	0.18
BLCA	chr1	6121123	Missense_Mutation	novel	P1632A	0.25
BLCA	chr1	6159513	Splice_Region	NA	G70G	0.5
BLCA	chr1	6142248	Silent	NA	A772A	0.76
BLCA	chr1	6130193	Intron	novel		0.34
BLCA	chr1	6124012	Silent	rs140639533	S1545S	0.21
BLCA	chr1	6142184	Missense_Mutation	NA	E794K	0.36	ResIII
BLCA	chr1	6148869	Silent	novel	L456L	0.51
BLCA	chr1	6126615	Silent	novel	I1345I	0.42
BLCA	chr1	6121165	Nonsense_Mutation	NA	R1618*	0.3
BLCA	chr1	6136833	Silent	NA	L823L	0.38
BLCA	chr1	6135283	Silent	NA	N939N	0.24
BLCA	chr1	6109868	Silent	rs575620025	L1835L	0.11
BLCA	chr1	6146746	Silent	NA	L503L	0.24
BLCA	chr1	6128857	Silent	NA	L1200L	0.07
BLCA	chr1	6110472	Silent	novel	L1768L	0.21
BRCA	chr1	6135255	Missense_Mutation	NA	R949W	0.28
BRCA	chr1	6168260	Missense_Mutation	novel	L33V	0.1
BRCA	chr1	6106405	Silent	novel	P1949P	0.33
BRCA	chr1	6128067	Silent	novel	V1294V	0.33
BRCA	chr1	6142249	Missense_Mutation	rs770153232	A772V	0.44	ResIII
BRCA	chr1	6155703	Silent	rs775725361	S134S	0.26
BRCA	chr1	6106423	Missense_Mutation	novel	N1943K	0.08
BRCA	chr1	6146375	Missense_Mutation	rs368618884	D547N	0.19
BRCA	chr1	6109915	Missense_Mutation	NA	H1820Y	0.15
BRCA	chr1	6134803	Frame_Shift_Del	NA	*G976Afs11**	0.49
BRCA	chr1	6134803	Missense_Mutation	NA	G976D	0.27
BRCA	chr1	6142193	Missense_Mutation	novel	R791W	0.4	ResIII
BRCA	chr1	6151039	Missense_Mutation	NA	K329N	0.31
BRCA	chr1	6131727	Missense_Mutation	NA	L1056M	0.17
BRCA	chr1	6142266	Silent	rs566097871	R766R	0.21
BRCA	chr1	6121533	Missense_Mutation	NA	D1580E	0.76
BRCA	chr1	6146265	Silent	NA	Y583Y	0.4
BRCA	chr1	6121237	Missense_Mutation	NA	A1594T	0.15
BRCA	chr1	6149315	Silent	novel	A364A	0.48
BRCA	chr1	6112203	Missense_Mutation	rs756114243	K1693E	0.41
CESC	chr1	6129028	Silent	novel	V1143V	0.23
CESC	chr1	6102234	3'UTR	novel		0.22
CESC	chr1	6154892	Silent	NA	L171L	0.14
CESC	chr1	6142514	Missense_Mutation	NA	R712H	0.46	ResIII
CESC	chr1	6125547	Missense_Mutation	novel	A1413T	0.5
CESC	chr1	6168262	Frame_Shift_Ins	novel	*G32Vfs15**	0.63
CESC	chr1	6109988	Frame_Shift_Ins	novel	*L1796Afs8**	0.19
CESC	chr1	6151143	Missense_Mutation	NA	E295K	0.27
CESC	chr1	6110427	Silent	novel	E1783E	0.37
CESC	chr1	6106686	Missense_Mutation	novel	R1891Q	0.55
CESC	chr1	6112921	Missense_Mutation	NA	E1664K	0.4
CESC	chr1	6144122	Silent	novel	I612I	0.11
CESC	chr1	6129064	Silent	novel	F1131F	0.08
CESC	chr1	6128581	Silent	novel	V1216V	0.19
CESC	chr1	6146355	Silent	novel	P553P	0.47
CESC	chr1	6154732	Missense_Mutation	NA	P225S	0.35
CESC	chr1	6109898	Silent	NA	L1825L	0.4
CHOL	chr1	6109916	Missense_Mutation	novel	N1819K	0.18
CHOL	chr1	6109917	Frame_Shift_Ins	novel	*N1819Tfs44**	0.18
COAD	chr1	6146395	Missense_Mutation	NA	R540H	0.19
COAD	chr1	6124609	Missense_Mutation	novel	A1483T	0.38
COAD	chr1	6124615	Missense_Mutation	NA	D1481N	0.2
COAD	chr1	6124084	Silent	NA	N1521N	0.34
COAD	chr1	6151130	Missense_Mutation	novel	S299L	0.28
COAD	chr1	6125586	Silent	novel	L1400L	0.36
COAD	chr1	6112158	Missense_Mutation	NA	A1708T	0.06
COAD	chr1	6168245	Missense_Mutation	novel	D38Y	0.21
COAD	chr1	6130297	Silent	novel	L1098L	0.24
COAD	chr1	6152470	Missense_Mutation	rs759139485	T271M	0.36
COAD	chr1	6149336	Frame_Shift_Del	novel	*C358Afs108**	0.07
COAD	chr1	6142440	Missense_Mutation	rs756337392	V737M	0.34	ResIII
COAD	chr1	6128887	Silent	rs767408616	D1190D	0.43
COAD	chr1	6101974	3'UTR	novel		0.08
COAD	chr1	6146843	Missense_Mutation	rs527562697	R471Q	0.27
COAD	chr1	6154730	Silent	rs201998865	P225P	0.39
COAD	chr1	6125158	Missense_Mutation	novel	A1446T	0.3
COAD	chr1	6142163	Missense_Mutation	rs567329094	A801T	0.45	ResIII
COAD	chr1	6109977	Missense_Mutation	novel	A1799V	0.11
COAD	chr1	6128136	Silent	rs201484104	D1271D	0.18
COAD	chr1	6106698	Frame_Shift_Del	NA	*P1887Rfs14**	0.5
COAD	chr1	6135374	Missense_Mutation	NA	A909D	0.27
COAD	chr1	6124589	Silent	rs150627163	G1489G	0.14
COAD	chr1	6130256	Missense_Mutation	novel	A1112V	0.11
COAD	chr1	6126681	Silent	novel	L1323L	0.17
COAD	chr1	6136751	Missense_Mutation	NA	R851C	0.29	ResIII
COAD	chr1	6131657	Missense_Mutation	novel	R1079Q	0.19
COAD	chr1	6142282	Missense_Mutation	novel	I761T	0.31	ResIII
COAD	chr1	6125213	Silent	novel	R1427R	0.17
COAD	chr1	6129058	Silent	rs773168274	R1133R	0.25
COAD	chr1	6128525	Missense_Mutation	rs754610815	K1235T	0.1
COAD	chr1	6149368	Missense_Mutation	novel	E347K	0.1
COAD	chr1	6111774	Splice_Site	NA	X1750_splice	0.31
COAD	chr1	6142163	Missense_Mutation	rs567329094	A801T	0.27	ResIII
COAD	chr1	6142296	Silent	rs199853430	A756A	0.59
COAD	chr1	6128887	Silent	rs767408616	D1190D	0.75
COAD	chr1	6142569	Missense_Mutation	rs774223603	D694N	0.31
COAD	chr1	6149332	Missense_Mutation	NA	D359N	0.19
COAD	chr1	6149043	Silent	NA	D398D	0.42
COAD	chr1	6128930	Missense_Mutation	NA	G1176D	0.32
COAD	chr1	6149023	Missense_Mutation	novel	E405V	0.1
COAD	chr1	6144134	Silent	NA	V608V	0.21
COAD	chr1	6151050	Missense_Mutation	novel	R326G	0.32
COAD	chr1	6149043	Silent	NA	D398D	0.5
COAD	chr1	6124012	Silent	rs140639533	S1545S	0.55
DLBC	chr1	6154778	Silent	rs575789517	A209A	0.25
DLBC	chr1	6129038	Missense_Mutation	novel	N1140I	0.17
DLBC	chr1	6136627	Silent	novel	V862V	0.1
ESCA	chr1	6151047	Missense_Mutation	rs751854770	R327C	0.38
ESCA	chr1	6136743	Missense_Mutation	novel	K853N	0.18	ResIII
ESCA	chr1	6142127	Splice_Site	novel	X812_splice	0.5
ESCA	chr1	6149362	Missense_Mutation	novel	C349R	0.18
ESCA	chr1	6136744	Missense_Mutation	novel	K853R	0.21	ResIII
ESCA	chr1	6112210	Silent	rs145305767	D1690D	0.43
ESCA	chr1	6151095	Missense_Mutation	NA	V311M	0.23
GBM	chr1	6151091	Missense_Mutation	novel	R312L	0.09
GBM	chr1	6123991	Silent	NA	P1552P	0.24
GBM	chr1	6129059	Missense_Mutation	NA	R1133H	0.29
GBM	chr1	6121122	Missense_Mutation	rs201640978	P1632L	0.58
GBM	chr1	6128999	Missense_Mutation	NA	S1153L	0.28
GBM	chr1	6146310	Silent	novel	R568R	0.16
GBM	chr1	6128585	Missense_Mutation	novel	P1215L	0.33
GBM	chr1	6106271	3'UTR	rs377199792		0.25
GBM	chr1	6125606	Missense_Mutation	novel	R1393Q	0.26
GBM	chr1	6128930	Missense_Mutation	NA	G1176D	0.22
GBM	chr1	6142329	Splice_Site	NA	X746_splice	0.15
GBM	chr1	6146250	Missense_Mutation	novel	K588N	0.19
GBM	chr1	6146686	Silent	novel	C523C	0.21
GBM	chr1	6136581	Missense_Mutation	novel	P878S	0.12	ResIII
GBM	chr1	6125142	Nonsense_Mutation	novel	W1451*	0.15
GBM	chr1	6128973	Missense_Mutation	NA	A1162S	0.27
GBM	chr1	6126676	Missense_Mutation	novel	R1325Q	0.39
GBM	chr1	6149378	Silent	NA	Q343Q	0.59
GBM	chr1	6110486	Missense_Mutation	rs752217521	R1764W	0.33
HNSC	chr1	6112938	Missense_Mutation	novel	S1658I	0.32
HNSC	chr1	6154802	Missense_Mutation	novel	F201L	0.21
HNSC	chr1	6112954	Missense_Mutation	novel	L1653V	0.18
HNSC	chr1	6149296	Missense_Mutation	novel	D371H	0.13
HNSC	chr1	6135384	Nonsense_Mutation	novel	E906*	0.19
HNSC	chr1	6142570	In_Frame_Del	novel	I693del	0.21
HNSC	chr1	6128574	Missense_Mutation	novel	I1219F	0.31
HNSC	chr1	6135249	Missense_Mutation	novel	E951K	0.12
HNSC	chr1	6130232	Missense_Mutation	novel	S1120L	0.16
KIRC	chr1	6151034	Missense_Mutation	NA	R331M	0.47
KIRC	chr1	6110473	Missense_Mutation	novel	L1768H	0.22
KIRC	chr1	6151108	Missense_Mutation	novel	I306M	0.31
KIRC	chr1	6154838	Silent	NA	G189G	0.26
KIRC	chr1	6148905	Missense_Mutation	NA	N444K	0.16
KIRP	chr1	6144128	Silent	rs779029688	Y610Y	0.52
KIRP	chr1	6152415	Silent	novel	S289S	0.18
KIRP	chr1	6154723	Missense_Mutation	NA	V228I	0.44
LAML	chr1	6149063	Missense_Mutation	novel	I392V	0.4
LGG	chr1	6142151	Frame_Shift_Ins	novel	*G805Wfs23**	0.4	ResIII
LGG	chr1	6126677	Missense_Mutation	NA	R1325W	0.18
LGG	chr1	6142266	Silent	rs566097871	R766R	0.4
LGG	chr1	6111774	Splice_Site	NA	X1750_splice	0.19
LGG	chr1	6112955	Missense_Mutation	novel	E1652D	0.35
LGG	chr1	6134748	Silent	novel	N994N	0.22
LIHC	chr1	6142126	Splice_Site	novel	X812_splice	0.36
LIHC	chr1	6146241	Nonsense_Mutation	NA	W591*	0.22
LIHC	chr1	6149265	Missense_Mutation	novel	K381T	0.47
LIHC	chr1	6168154	Missense_Mutation	novel	K68I	0.35
LIHC	chr1	6154747	Missense_Mutation	novel	V220I	0.27
LIHC	chr1	6151119	Missense_Mutation	novel	S303C	0.28
LIHC	chr1	6136747	Missense_Mutation	NA	L852H	0.31	ResIII
LIHC	chr1	6102011	3'UTR	novel		0.5
LUAD	chr1	6143891	Missense_Mutation	novel	L659V	0.16
LUAD	chr1	6154703	Silent	NA	P234P	0.9
LUAD	chr1	6136830	Silent	novel	T824T	0.1
LUAD	chr1	6144098	Silent	novel	D620D	0.29
LUAD	chr1	6134215	Silent	NA	L1019L	0.33
LUAD	chr1	6125226	Missense_Mutation	novel	G1423V	0.38
LUAD	chr1	6125227	Missense_Mutation	novel	G1423C	0.38
LUAD	chr1	6154713	Missense_Mutation	rs370035599	P231L	0.17
LUAD	chr1	6125775	Nonsense_Mutation	NA	E1388*	0.06
LUAD	chr1	6142423	Silent	novel	L742L	0.14
LUAD	chr1	6131699	Missense_Mutation	novel	Y1065C	0.16
LUAD	chr1	6111780	Silent	rs147401166	I1748I	0.08
LUAD	chr1	6146272	Missense_Mutation	NA	R581L	0.06
LUAD	chr1	6121507	Missense_Mutation	NA	P1589H	0.19
LUAD	chr1	6146338	Missense_Mutation	rs759443731	G559E	0.77
LUAD	chr1	6128602	Missense_Mutation	novel	M1209I	0.14
LUAD	chr1	6146403	Silent	rs771640708	V537V	0.43
LUAD	chr1	6136597	Silent	novel	L872L	0.15
LUAD	chr1	6134180	Missense_Mutation	NA	K1031M	0.32
LUAD	chr1	6128848	Silent	rs542019061	D1203D	0.36
LUAD	chr1	6146351	Missense_Mutation	novel	D555H	0.06
LUAD	chr1	6134754	Nonsense_Mutation	NA	C992*	0.14
LUAD	chr1	6124548	Missense_Mutation	NA	R1503H	0.16
LUAD	chr1	6126578	Missense_Mutation	NA	D1358Y	0.37
LUAD	chr1	6148898	Silent	NA	L447L	0.64
LUAD	chr1	6152534	Missense_Mutation	novel	P250T	0.38
LUAD	chr1	6136523	Missense_Mutation	NA	R897M	0.19
LUAD	chr1	6109855	Missense_Mutation	NA	Q1840K	0.28
LUAD	chr1	6125778	Missense_Mutation	novel	P1387T	0.33
LUAD	chr1	6146264	Missense_Mutation	rs751825704	R584C	0.28
LUAD	chr1	6109938	Missense_Mutation	NA	L1812Q	0.73
LUAD	chr1	6134802	Silent	novel	G976G	0.28
LUAD	chr1	6112965	Missense_Mutation	NA	D1649G	0.34
LUAD	chr1	6154827	Missense_Mutation	novel	R193L	0.48
LUAD	chr1	6155596	Splice_Region	novel		0.38
LUAD	chr1	6143930	Nonsense_Mutation	NA	E646*	0.21
LUAD	chr1	6109855	Missense_Mutation	NA	Q1840K	0.33
LUAD	chr1	6143828	Missense_Mutation	rs139532134	V680L	0.15
LUAD	chr1	6130154	Intron	novel		0.14
LUAD	chr1	6143932	Splice_Site	NA	X645_splice	0.11
LUAD	chr1	6155637	Silent	NA	H156H	0.17
LUAD	chr1	6148855	Missense_Mutation	novel	T461N	0.39
LUAD	chr1	6136785	Silent	rs368959733	I839I	0.47
LUAD	chr1	6151113	Missense_Mutation	NA	S305C	0.2
LUAD	chr1	6106771	Missense_Mutation	novel	Q1863K	0.24
LUAD	chr1	6142453	Silent	novel	T732T	0.21
LUAD	chr1	6135328	Silent	novel	L924L	0.11
LUAD	chr1	6149365	Missense_Mutation	novel	V348L	0.1
LUAD	chr1	6148880	Missense_Mutation	novel	G453S	0.32
LUAD	chr1	6125177	Missense_Mutation	novel	W1439C	0.17
LUSC	chr1	6128931	Missense_Mutation	novel	G1176C	0.2
LUSC	chr1	6109825	Missense_Mutation	novel	N1850D	0.21
LUSC	chr1	6136527	Nonsense_Mutation	NA	E896*	0.24
LUSC	chr1	6125776	Silent	rs773893368	P1387P	0.18
LUSC	chr1	6136630	Missense_Mutation	novel	R861S	0.22	ResIII
LUSC	chr1	6136798	Missense_Mutation	novel	I835N	0.09	ResIII
LUSC	chr1	6106729	Missense_Mutation	novel	R1877W	0.16
LUSC	chr1	6136574	Missense_Mutation	novel	Q880R	0.25
LUSC	chr1	6106635	Missense_Mutation	novel	G1908E	0.63
LUSC	chr1	6106636	Missense_Mutation	NA	G1908R	0.63
LUSC	chr1	6109872	Missense_Mutation	NA	C1834Y	0.08
LUSC	chr1	6152498	Missense_Mutation	novel	G262W	0.1
LUSC	chr1	6112252	Missense_Mutation	novel	E1676D	0.09
LUSC	chr1	6109941	Missense_Mutation	NA	Y1811C	0.14
LUSC	chr1	6142304	Missense_Mutation	novel	V754F	0.08	ResIII
LUSC	chr1	6134241	Missense_Mutation	NA	N1011D	0.22
LUSC	chr1	6134838	Silent	novel	L964L	0.17
LUSC	chr1	6112993	Missense_Mutation	novel	V1640L	0.36
LUSC	chr1	6135307	Silent	novel	R931R	0.69
LUSC	chr1	6128863	Silent	novel	E1198E	0.74
LUSC	chr1	6109894	Missense_Mutation	novel	A1827S	0.12
LUSC	chr1	6142604	Missense_Mutation	NA	P682L	0.45
LUSC	chr1	6152478	Silent	NA	G268G	0.38
LUSC	chr1	6128179	Missense_Mutation	novel	Y1257C	0.73
LUSC	chr1	6146326	Frame_Shift_Del	novel	*G563Afs30**	0.53
LUSC	chr1	6135278	Missense_Mutation	novel	P941Q	0.07
LUSC	chr1	6131665	Silent	novel	G1076G	0.19
LUSC	chr1	6144056	Silent	rs772371613	Y634Y	0.21
LUSC	chr1	6143820	Splice_Region	novel		0.14
LUSC	chr1	6109867	Missense_Mutation	NA	A1836T	0.6
LUSC	chr1	6128991	Missense_Mutation	novel	E1156K	0.18
MESO	chr1	6130323	Missense_Mutation	rs774559118	G1090R	0.39
OV	chr1	6142488	Missense_Mutation	NA	T721S	0.48	ResIII
OV	chr1	6112247	Missense_Mutation	novel	I1678S	0.11
OV	chr1	6109976	Silent	rs376607024	A1799A	0.97
OV	chr1	6131633	Missense_Mutation	NA	N1087I	0.28
OV	chr1	6142291	Missense_Mutation	novel	L758P	0.5	ResIII
OV	chr1	6126683	Silent	novel	L1323L	0.15
OV	chr1	6110453	Missense_Mutation	novel	E1775K	0.24
OV	chr1	6144075	Missense_Mutation	novel	D628A	0.1
OV	chr1	6142529	Missense_Mutation	novel	G707D	0.06	ResIII
OV	chr1	6128958	Missense_Mutation	NA	M1167V	0.32
OV	chr1	6146375	Missense_Mutation	novel	D547Y	0.08
OV	chr1	6155679	Silent	novel	G142G	0.06
PAAD	chr1	6106443	Missense_Mutation	novel	G1937R	0.13
PAAD	chr1	6109867	Missense_Mutation	NA	A1836T	0.1
PAAD	chr1	6121109	Silent	rs200772880	P1636P	0.09
PAAD	chr1	6124660	Missense_Mutation	novel	A1466S	0.26
PAAD	chr1	6142162	Missense_Mutation	novel	A801V	0.1	ResIII
PAAD	chr1	6151046	Missense_Mutation	rs763049065	R327H	0.09
PAAD	chr1	6154899	Splice_Site	novel	X169_splice	0.13
PAAD	chr1	6155690	Missense_Mutation	novel	A139S	0.17
PRAD	chr1	6142162	Missense_Mutation	novel	A801V	0.07	ResIII
PRAD	chr1	6106642	Missense_Mutation	NA	R1906C	0.32
PRAD	chr1	6155609	Nonsense_Mutation	novel	Q166*	0.11
PRAD	chr1	6121156	Missense_Mutation	rs772221709	R1621W	0.22
PRAD	chr1	6134721	Silent	rs780276723	A1003A	0.39
PRAD	chr1	6142553	Missense_Mutation	novel	T699I	0.33
PRAD	chr1	6146263	Missense_Mutation	rs141210110	R584H	0.34
READ	chr1	6168163	Missense_Mutation	rs761147748	R65Q	0.69
READ	chr1	6112921	Missense_Mutation	NA	E1664K	0.61
READ	chr1	6112210	Silent	rs145305767	D1690D	0.34
READ	chr1	6123990	Missense_Mutation	novel	A1553T	0.43
READ	chr1	6146250	Missense_Mutation	novel	K588N	0.1
READ	chr1	6149346	Frame_Shift_Ins	novel	*E354Gfs35**	0.73
READ	chr1	6121121	Silent	rs758058613	P1632P	0.72
READ	chr1	6131643	Missense_Mutation	rs760743983	D1084N	0.73
READ	chr1	6152448	Silent	rs200170499	F278F	0.41
SARC	chr1	6149305	Missense_Mutation	novel	V368I	0.45
SARC	chr1	6154788	Missense_Mutation	novel	A206V	0.15
SARC	chr1	6135347	Missense_Mutation	novel	K918M	0.28
SARC	chr1	6144023	Splice_Site	novel	X645_splice	0.19
SARC	chr1	6144024	Missense_Mutation	novel	R645K	0.2
SARC	chr1	6154876	Missense_Mutation	novel	P177S	0.45
SARC	chr1	6102333	3'UTR	novel		0.33
SARC	chr1	6102468	3'UTR	novel		0.45
SKCM	chr1	6125851	Silent	NA	Q1362Q	0.34
SKCM	chr1	6159441	Silent	NA	S94S	0.36
SKCM	chr1	6142271	Missense_Mutation	NA	E765K	0.52	ResIII
SKCM	chr1	6124011	Missense_Mutation	NA	D1546N	0.34
SKCM	chr1	6136599	Silent	novel	L872L	0.27
SKCM	chr1	6106765	Missense_Mutation	novel	E1865K	0.22
SKCM	chr1	6106766	Silent	novel	L1864L	0.21
SKCM	chr1	6126743	Missense_Mutation	novel	E1303K	0.59
SKCM	chr1	6149296	Missense_Mutation	novel	D371N	0.36
SKCM	chr1	6134160	Missense_Mutation	novel	D1038N	0.3
SKCM	chr1	6146763	Missense_Mutation	novel	P498S	0.36
SKCM	chr1	6128909	Missense_Mutation	NA	S1183F	0.35
SKCM	chr1	6154721	Silent	rs768857681	V228V	0.31
SKCM	chr1	6143840	Missense_Mutation	rs142551574	D676N	0.44
SKCM	chr1	6129046	Silent	rs774052512	I1137I	0.22
SKCM	chr1	6112159	Silent	rs772790386	I1707I	0.15
SKCM	chr1	6142288	Missense_Mutation	NA	S759F	0.13	ResIII
SKCM	chr1	6128207	Missense_Mutation	novel	D1248N	0.91
SKCM	chr1	6128208	Silent	novel	K1247K	0.91
SKCM	chr1	6136581	Missense_Mutation	novel	P878S	0.3	ResIII
SKCM	chr1	6146683	Silent	novel	S524S	0.34
SKCM	chr1	6146684	Missense_Mutation	novel	S524F	0.34
SKCM	chr1	6152501	Missense_Mutation	novel	D261N	0.31
SKCM	chr1	6106423	Silent	NA	N1943N	0.42
SKCM	chr1	6124550	Silent	novel	T1502T	0.33
SKCM	chr1	6143864	Missense_Mutation	NA	D668N	0.3
SKCM	chr1	6146705	Missense_Mutation	NA	G517E	0.21
SKCM	chr1	6168248	Missense_Mutation	rs778192266	D37N	0.28
SKCM	chr1	6168249	Silent	rs146996909	F36F	0.3
SKCM	chr1	6154739	Silent	novel	I222I	0.43
SKCM	chr1	6124606	Missense_Mutation	NA	E1484K	0.34
SKCM	chr1	6112254	Missense_Mutation	novel	E1676K	0.25
SKCM	chr1	6136581	Missense_Mutation	novel	P878S	0.54	ResIII
SKCM	chr1	6146370	Missense_Mutation	novel	M548I	0.36
SKCM	chr1	6124040	Missense_Mutation	NA	G1536E	0.34
SKCM	chr1	6131668	Silent	rs549235865	T1075T	0.13
SKCM	chr1	6134237	Missense_Mutation	NA	G1012D	0.3
SKCM	chr1	6131639	Missense_Mutation	novel	R1085K	0.21
SKCM	chr1	6121154	Silent	NA	R1621R	0.39
SKCM	chr1	6128871	Missense_Mutation	NA	G1196S	0.21
SKCM	chr1	6142191	Silent	NA	R791R	0.31
SKCM	chr1	6143931	Splice_Region	NA	R645R	0.41
SKCM	chr1	6159488	Missense_Mutation	NA	E79K	0.63
SKCM	chr1	6144080	Silent	rs777063752	I626I	0.79
SKCM	chr1	6106702	Missense_Mutation	NA	P1886S	0.22
SKCM	chr1	6168237	Silent	NA	F40F	0.15
SKCM	chr1	6146327	Missense_Mutation	rs150733401	G563S	0.22
SKCM	chr1	6168237	Silent	NA	F40F	0.38
SKCM	chr1	6135256	Silent	novel	V948V	0.17
SKCM	chr1	6121503	Silent	NA	L1590L	0.74
SKCM	chr1	6135289	Silent	NA	F937F	0.23
SKCM	chr1	6149297	Silent	NA	L370L	0.33
SKCM	chr1	6112183	Silent	NA	G1699G	0.24
SKCM	chr1	6125564	Missense_Mutation	NA	P1407L	0.44
SKCM	chr1	6134127	Splice_Site	NA	X1048_splice	0.15
SKCM	chr1	6124081	Silent	NA	G1522G	0.17
SKCM	chr1	6134792	Missense_Mutation	NA	V980I	0.63
SKCM	chr1	6146295	Silent	rs756370204	P573P	0.36
SKCM	chr1	6128106	Missense_Mutation	NA	M1281I	0.08
SKCM	chr1	6135361	Silent	NA	K913K	0.07
SKCM	chr1	6142136	Missense_Mutation	NA	R810C	0.21	ResIII
SKCM	chr1	6128992	Silent	NA	E1155E	0.66
SKCM	chr1	6129061	Silent	novel	S1132S	0.9
SKCM	chr1	6131666	Missense_Mutation	novel	G1076E	0.38
SKCM	chr1	6154859	Silent	novel	S182S	0.67
SKCM	chr1	6128862	Missense_Mutation	NA	E1199K	0.44
SKCM	chr1	6128865	Missense_Mutation	NA	E1198K	0.39
SKCM	chr1	6142137	Silent	rs747255491	F809F	0.16
SKCM	chr1	6144080	Silent	rs777063752	I626I	0.22
SKCM	chr1	6154868	Silent	NA	I179I	0.16
SKCM	chr1	6155718	Splice_Site	NA	X130_splice	0.29
SKCM	chr1	6135253	Silent	NA	R949R	0.48
SKCM	chr1	6109826	Silent	NA	G1849G	0.07
SKCM	chr1	6154715	Silent	novel	P230P	0.12
SKCM	chr1	6154716	Missense_Mutation	novel	P230L	0.12
SKCM	chr1	6149033	Missense_Mutation	novel	E402K	0.19
SKCM	chr1	6142177	Missense_Mutation	NA	S796F	0.75	ResIII
SKCM	chr1	6146356	Missense_Mutation	rs375622476	P553L	0.42
SKCM	chr1	6146357	Missense_Mutation	NA	P553S	0.2
SKCM	chr1	6154871	Silent	NA	K178K	0.17
SKCM	chr1	6112970	Silent	NA	I1647I	0.12
SKCM	chr1	6152450	Missense_Mutation	NA	F278I	0.1
SKCM	chr1	6159402	Silent	NA	K107K	0.5
SKCM	chr1	6144142	Missense_Mutation	NA	G606R	0.3
SKCM	chr1	6112921	Missense_Mutation	NA	E1664K	0.16
SKCM	chr1	6143890	Missense_Mutation	novel	L659P	0.34
SKCM	chr1	6154742	Silent	novel	T221T	0.18
SKCM	chr1	6142285	Missense_Mutation	rs747682429	T760I	0.47	ResIII
SKCM	chr1	6112278	Splice_Site	novel	X1668_splice	0.47
SKCM	chr1	6130174	Intron	novel		0.6
SKCM	chr1	6155601	Splice_Region	novel	L168L	0.45
SKCM	chr1	6134811	Silent	NA	S973S	0.38
SKCM	chr1	6144080	Silent	rs777063752	I626I	0.47
STAD	chr1	6129051	Missense_Mutation	NA	R1136C	0.24
STAD	chr1	6155703	Silent	rs775725361	S134S	0.16
STAD	chr1	6168163	Missense_Mutation	rs761147748	R65Q	0.05
STAD	chr1	6142539	Nonsense_Mutation	novel	Q704*	0.21	ResIII
STAD	chr1	6149332	Missense_Mutation	NA	D359N	0.32
STAD	chr1	6128910	Missense_Mutation	NA	S1183P	0.27
STAD	chr1	6155670	Silent	rs140138233	D145D	0.19
STAD	chr1	6146818	Silent	NA	E479E	0.19
STAD	chr1	6148911	Silent	NA	C442C	0.29
STAD	chr1	6131687	Missense_Mutation	NA	R1069Q	0.44
STAD	chr1	6142514	Missense_Mutation	NA	R712H	0.23	ResIII
STAD	chr1	6144066	Missense_Mutation	NA	I631T	0.28
STAD	chr1	6109895	Silent	rs200881726	N1826N	0.3
STAD	chr1	6128966	Missense_Mutation	NA	R1164H	0.31
STAD	chr1	6125234	Splice_Site	novel	X1421_splice	0.43
STAD	chr1	6129045	Missense_Mutation	novel	G1138S	0.38
STAD	chr1	6142135	Missense_Mutation	rs147522329	R810H	0.4	ResIII
STAD	chr1	6152511	Missense_Mutation	novel	K257N	0.41
STAD	chr1	6112277	Missense_Mutation	NA	D1668V	0.24
STAD	chr1	6142152	Silent	NA	S804S	0.21
STAD	chr1	6152442	Frame_Shift_Del	NA	*I281Sfs185**	0.26
STAD	chr1	6154723	Missense_Mutation	NA	V228I	0.54
STAD	chr1	6154721	Silent	rs768857681	V228V	0.16
STAD	chr1	6109900	Missense_Mutation	NA	L1825F	0.08
STAD	chr1	6124616	Silent	rs765484235	A1480A	0.2
STAD	chr1	6136750	Missense_Mutation	novel	R851H	0.31	ResIII
STAD	chr1	6124013	Missense_Mutation	rs201559496	S1545L	0.29
STAD	chr1	6126613	Missense_Mutation	NA	R1346H	0.23
STAD	chr1	6142325	Missense_Mutation	novel	H747N	0.18	ResIII
STAD	chr1	6149333	Silent	rs147670357	C358C	0.15
STAD	chr1	6121225	Missense_Mutation	rs761874883	A1598T	0.48
STAD	chr1	6146407	Missense_Mutation	NA	T536M	0.56
STAD	chr1	6124582	Missense_Mutation	rs761795865	R1492W	0.2
STAD	chr1	6154767	Missense_Mutation	rs767762669	V213A	0.12
STAD	chr1	6128060	Missense_Mutation	NA	E1297K	0.21
STAD	chr1	6111825	Silent	rs764640532	Y1733Y	0.15
STAD	chr1	6149333	Silent	rs147670357	C358C	0.11
STAD	chr1	6109943	Silent	rs191295192	A1810A	0.23
STAD	chr1	6136633	Frame_Shift_Del	novel	*F860Lfs4**	0.15	ResIII
STAD	chr1	6129005	Missense_Mutation	NA	R1151Q	0.13
STAD	chr1	6143930	Nonsense_Mutation	NA	E646*	0.39
STAD	chr1	6136633	Frame_Shift_Del	novel	*F860Lfs4**	0.12	ResIII
STAD	chr1	6144039	Missense_Mutation	NA	A640V	0.12
STAD	chr1	6152466	Silent	rs140463225	A272A	0.23
STAD	chr1	6129060	Missense_Mutation	NA	R1133C	0.17
STAD	chr1	6146319	Silent	NA	S565S	0.31
THCA	chr1	6134742	Silent	NA	P996P	0.3
THYM	chr1	6109910	Silent	rs149601798	P1821P	0.27
UCEC	chr1	6125124	Missense_Mutation	NA	R1457Q	0.22
UCEC	chr1	6136633	Frame_Shift_Del	novel	*F860Lfs4**	0.15	ResIII
UCEC	chr1	6110429	Missense_Mutation	NA	E1783K	0.35
UCEC	chr1	6134162	Missense_Mutation	rs746052525	R1037Q	0.33
UCEC	chr1	6128524	Missense_Mutation	NA	K1235N	0.47
UCEC	chr1	6146395	Missense_Mutation	NA	R540H	0.16
UCEC	chr1	6103078	3'UTR	novel		0.15
UCEC	chr1	6125109	Missense_Mutation	novel	K1462T	0.38
UCEC	chr1	6129005	Missense_Mutation	NA	R1151Q	0.31
UCEC	chr1	6155709	Silent	novel	K132K	0.32
UCEC	chr1	6159503	Missense_Mutation	novel	E74K	0.08
UCEC	chr1	6136796	Missense_Mutation	novel	L836M	0.19	ResIII
UCEC	chr1	6159373	Missense_Mutation	novel	D117G	0.26
UCEC	chr1	6112158	Missense_Mutation	NA	A1708T	0.51
UCEC	chr1	6110401	Missense_Mutation	NA	R1792M	0.39
UCEC	chr1	6106665	Missense_Mutation	novel	S1898I	0.42
UCEC	chr1	6168163	Missense_Mutation	rs761147748	R65Q	0.33
UCEC	chr1	6105109	3'UTR	novel		0.21
UCEC	chr1	6131643	Missense_Mutation	rs760743983	D1084N	0.08
UCEC	chr1	6109819	Missense_Mutation	NA	P1852S	0.18
UCEC	chr1	6112995	Missense_Mutation	novel	E1639G	0.06
UCEC	chr1	6149055	Nonsense_Mutation	NA	W394*	0.28
UCEC	chr1	6151138	Missense_Mutation	NA	R296S	0.29
UCEC	chr1	6125136	Missense_Mutation	NA	V1453A	0.3
UCEC	chr1	6110407	Missense_Mutation	NA	A1790V	0.3
UCEC	chr1	6121155	Missense_Mutation	rs147417867	R1621Q	0.12
UCEC	chr1	6149347	Missense_Mutation	NA	E354K	0.23
UCEC	chr1	6151116	Missense_Mutation	rs768430028	A304T	0.18
UCEC	chr1	6121193	Silent	rs777565554	H1608H	0.15
UCEC	chr1	6125142	Nonsense_Mutation	novel	W1451*	0.2
UCEC	chr1	6106739	Silent	rs200068048	A1873A	0.24
UCEC	chr1	6102438	3'UTR	novel		0.29
UCEC	chr1	6124638	Missense_Mutation	novel	R1473Q	0.6
UCEC	chr1	6126657	Missense_Mutation	NA	Q1331H	0.41
UCEC	chr1	6130236	Missense_Mutation	NA	D1119N	0.42
UCEC	chr1	6143862	Silent	rs139925783	D668D	0.36
UCEC	chr1	6159435	Silent	NA	N96N	0.16
UCEC	chr1	6126625	Missense_Mutation	novel	G1342D	0.31
UCEC	chr1	6142297	Missense_Mutation	rs144145989	A756V	0.5	ResIII
UCEC	chr1	6102177	3'UTR	novel		0.41
UCEC	chr1	6142156	Missense_Mutation	novel	R803Q	0.38	ResIII
UCEC	chr1	6142490	Missense_Mutation	novel	D720A	0.12	ResIII
UCEC	chr1	6159399	Missense_Mutation	novel	E108D	0.16
UCEC	chr1	6106689	Missense_Mutation	novel	A1890D	0.12
UCEC	chr1	6135329	Missense_Mutation	novel	L924P	0.2
UCEC	chr1	6154724	Silent	novel	A227A	0.33
UCEC	chr1	6154827	Missense_Mutation	novel	R193Q	0.45
UCEC	chr1	6103150	3'UTR	novel		0.26
UCEC	chr1	6106287	Missense_Mutation	NA	D1953G	0.49
UCEC	chr1	6109943	Silent	rs191295192	A1810A	0.39
UCEC	chr1	6129044	Missense_Mutation	novel	G1138D	0.33
UCEC	chr1	6144134	Silent	NA	V608V	0.53
UCEC	chr1	6126731	Frame_Shift_Del	NA	*E1307Kfs94**	0.25
UCEC	chr1	6112158	Missense_Mutation	NA	A1708T	0.51
UCEC	chr1	6135276	Missense_Mutation	rs748825072	A942T	0.53
UCEC	chr1	6130253	Missense_Mutation	novel	D1113G	0.21
UCEC	chr1	6106288	Splice_Site	novel	X1953_splice	0.5
UCEC	chr1	6129040	Missense_Mutation	novel	Q1139H	0.53
UCEC	chr1	6135394	Missense_Mutation	novel	E902D	0.22
UCEC	chr1	6136561	Missense_Mutation	novel	E884D	0.54
UCEC	chr1	6136862	Nonsense_Mutation	novel	E814*	0.59	ResIII
UCEC	chr1	6146737	Silent	novel	I506I	0.41
UCEC	chr1	6152458	Missense_Mutation	novel	K275T	0.52
UCEC	chr1	6128915	Missense_Mutation	novel	S1181L	0.17
UCEC	chr1	6136743	Missense_Mutation	novel	K853N	0.26	ResIII
UCEC	chr1	6142569	Missense_Mutation	rs774223603	D694N	0.37
UCEC	chr1	6123962	Missense_Mutation	rs781286534	P1562L	0.48
UCEC	chr1	6146404	Missense_Mutation	NA	V537A	0.44
UCEC	chr1	6128930	Missense_Mutation	NA	G1176D	0.36
UCEC	chr1	6152419	Missense_Mutation	NA	G288A	0.34
UCEC	chr1	6105388	3'UTR	novel		0.33
UCEC	chr1	6134229	Missense_Mutation	NA	D1015N	0.33
UCEC	chr1	6142188	Silent	novel	E792E	0.44
UCEC	chr1	6111871	Missense_Mutation	novel	L1718P	0.28
UCEC	chr1	6142598	Missense_Mutation	novel	V684A	0.27
UCEC	chr1	6146799	Missense_Mutation	novel	V486M	0.39
UCEC	chr1	6102235	3'UTR	novel		0.6
UCEC	chr1	6102276	3'UTR	NA		0.47
UCEC	chr1	6105234	3'UTR	novel		0.4
UCEC	chr1	6121225	Missense_Mutation	rs761874883	A1598T	0.14
UCEC	chr1	6142538	Missense_Mutation	novel	Q704P	0.15	ResIII
UCEC	chr1	6151031	Splice_Site	novel	X332_splice	0.1
UCEC	chr1	6154871	Missense_Mutation	novel	K178N	0.19
UCEC	chr1	6159438	Silent	rs368591455	P95P	0.12
UCEC	chr1	6106642	Missense_Mutation	NA	R1906C	0.4
UCEC	chr1	6124616	Silent	rs765484235	A1480A	0.39
UCEC	chr1	6130236	Missense_Mutation	NA	D1119N	0.36
UCEC	chr1	6146843	Missense_Mutation	rs527562697	R471Q	0.39
UCEC	chr1	6149036	Missense_Mutation	novel	D401N	0.5
UCEC	chr1	6151047	Missense_Mutation	rs751854770	R327C	0.41
UCEC	chr1	6106450	Silent	novel	P1934P	0.32
UCEC	chr1	6149322	Missense_Mutation	rs746309035	P362L	0.2
UCEC	chr1	6125606	Missense_Mutation	novel	R1393Q	0.33
UCEC	chr1	6143912	Missense_Mutation	novel	D652Y	0.37
UCEC	chr1	6146282	Missense_Mutation	novel	M578V	0.24
UCEC	chr1	6151046	Missense_Mutation	rs763049065	R327H	0.24
UCEC	chr1	6112158	Missense_Mutation	NA	A1708T	0.4
UCEC	chr1	6135380	Missense_Mutation	novel	E907G	0.1
UCEC	chr1	6146395	Missense_Mutation	NA	R540H	0.3
UCEC	chr1	6154660	Missense_Mutation	novel	G249W	0.39
UCEC	chr1	6102947	3'UTR	novel		0.5
UCEC	chr1	6126650	Missense_Mutation	novel	D1334Y	0.43
UCEC	chr1	6143896	Missense_Mutation	novel	K657R	0.45
UCEC	chr1	6136573	Missense_Mutation	NA	Q880H	0.2
UCEC	chr1	6159420	Missense_Mutation	novel	K101N	0.08
UCEC	chr1	6105280	3'UTR	novel		0.27
UCEC	chr1	6125175	Missense_Mutation	novel	G1440D	0.24
UCEC	chr1	6125522	Splice_Site	novel	X1420_splice	0.37
UCEC	chr1	6142236	Silent	rs754931120	Y776Y	0.38
UCEC	chr1	6102800	3'UTR	novel		0.71
UCEC	chr1	6106434	Missense_Mutation	novel	V1940I	0.19
UCEC	chr1	6112249	Silent	rs759193285	P1677P	0.36
UCEC	chr1	6142265	Missense_Mutation	NA	E767K	0.41	ResIII
UCEC	chr1	6124639	Missense_Mutation	novel	R1473W	0.36
UCEC	chr1	6136812	Silent	novel	T830T	0.25
UCEC	chr1	6102276	3'UTR	NA		0.48
UCEC	chr1	6129063	Missense_Mutation	NA	S1132G	0.56
UCEC	chr1	6136784	Missense_Mutation	NA	E840K	0.54	ResIII
UCEC	chr1	6144055	Missense_Mutation	NA	D635N	0.36
UCEC	chr1	6146745	Nonsense_Mutation	NA	E504*	0.28
UCEC	chr1	6136640	Splice_Site	novel	X859_splice	0.19
UCEC	chr1	6106287	Missense_Mutation	NA	D1953A	0.19
UCEC	chr1	6124543	Missense_Mutation	novel	G1505R	0.4
UCEC	chr1	6126619	Missense_Mutation	NA	R1344H	0.39
UCEC	chr1	6135346	Missense_Mutation	NA	K918N	0.37
UCEC	chr1	6136573	Missense_Mutation	NA	Q880H	0.32
UCEC	chr1	6124026	Missense_Mutation	novel	E1541K	0.75
UCEC	chr1	6126663	Missense_Mutation	novel	E1329D	0.58
UCEC	chr1	6128110	Missense_Mutation	novel	N1280S	0.88
UCEC	chr1	6142248	Silent	NA	A772A	0.49
UCEC	chr1	6151046	Missense_Mutation	rs763049065	R327H	0.3
UCEC	chr1	6154871	Silent	NA	K178K	0.39
UCEC	chr1	6105179	3'UTR	novel		0.46
UCEC	chr1	6136619	Missense_Mutation	novel	S865N	0.46	ResIII
UCEC	chr1	6142263	Missense_Mutation	novel	E767D	0.13	ResIII
UCEC	chr1	6149407	Missense_Mutation	novel	D334Y	0.41
UCEC	chr1	6102276	3'UTR	NA		0.47
UCEC	chr1	6125181	Missense_Mutation	novel	R1438H	0.42
UCEC	chr1	6136578	Frame_Shift_Del	novel	*L879Ffs15**	0.48
UCEC	chr1	6146822	Missense_Mutation	rs148974462	T478M	0.44
UCEC	chr1	6131656	Silent	NA	R1079R	0.12
UCEC	chr1	6102276	3'UTR	NA		0.71
UCEC	chr1	6134802	Silent	rs377324742	G976G	0.1
UCEC	chr1	6110401	Missense_Mutation	NA	R1792M	0.17
UCEC	chr1	6103028	3'UTR	novel		0.47
UCEC	chr1	6124592	Silent	rs776786583	D1488D	0.58
UCEC	chr1	6106673	Silent	rs756618256	S1895S	0.33
UCEC	chr1	6136619	Missense_Mutation	novel	S865N	0.35	ResIII
UCEC	chr1	6155703	Silent	rs775725361	S134S	0.46
UCEC	chr1	6168195	Silent	novel	K54K	0.31
UCEC	chr1	6124604	Missense_Mutation	novel	E1484D	0.42
UCS	chr1	6168163	Missense_Mutation	rs761147748	R65Q	0.19
UCS	chr1	6149403	Missense_Mutation	novel	G335A	0.49
UCS	chr1	6130315	Missense_Mutation	NA	Q1092H	0.37
UCS	chr1	6142533	Missense_Mutation	novel	E706K	0.37	ResIII
UCS	chr1	6168244	Missense_Mutation	novel	D38G	0.33
UVM	chr1	6154712	Silent	rs141326175	P231P	0.45

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.1085	0.00029523
DLBC	DEL	0.1875	0.011841
GBM	DEL	0.2097	2.0772e-26
HNSC	DEL	0.1398	7.0766e-07
KIRC	DEL	0.1458	2.3538e-09
KIRP	DEL	0.184	1.462e-09
LIHC	DEL	0.4135	1.1606e-33
LUAD	DEL	0.1492	0.0024765
LUSC	DEL	0.3513	2.5882e-07
MESO	DEL	0.3793	2.434e-07
READ	DEL	0.3758	2.1758e-10
SKCM	DEL	0.1853	5.1876e-09
TGCT	DEL	0.1867	0.00046313
UCS	DEL	0.3036	0.0051125

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0058	Kaplan-Meier Survival Analysis
MESO	0.05	Kaplan-Meier Survival Analysis
ACC	0.018	Kaplan-Meier Survival Analysis
BRCA	0.00028	Kaplan-Meier Survival Analysis
COAD	0.0048	Kaplan-Meier Survival Analysis
PAAD	0.00086	Kaplan-Meier Survival Analysis
READ	0.044	Kaplan-Meier Survival Analysis
KICH	0.0049	Kaplan-Meier Survival Analysis
UCEC	0.0001	Kaplan-Meier Survival Analysis
LIHC	0.016	Kaplan-Meier Survival Analysis
LGG	0.00078	Kaplan-Meier Survival Analysis
CHOL	0.047	Kaplan-Meier Survival Analysis
UVM	0.049	Kaplan-Meier Survival Analysis
OV	0.0099	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000116254 (Gene tree)
Gene ID: 26038
Gene Symbol: CHD5
Alias: -
Full Name: chromodomain helicase DNA binding protein 5
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 78,348 bases
Position: chr1:6,101,787-6,180,134
Accession: 16816
RBP type: canonical RBP
Summary: This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma. [provided by RefSeq, Feb 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000262450	ResIII	PF04851.15	3.1e-07	1	1

Expression

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.