EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24823640	Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.	Cancer Cell	2014 May 12	Aytes A	doi: 10.1016/j.ccr.2014.03.017.
22912832	Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas.	PLoS One	2012	Kim HE	doi: 10.1371/journal.pone.0043223
17205517	CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer.	Int J Cancer	2007 Apr 1	O'Brien SL	-
19102762	Expression of centromere protein F (CENP-F) associated with higher FDG uptake on PET/CT, detected by cDNA microarray, predicts high-risk patients with primary breast cancer.	BMC Cancer	2008 Dec 22	Ueda S	doi: 10.1186/1471-2407-8-384.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr1	214643090	Silent	rs200241672	L1584L	0.46
ACC	chr1	214643267	Silent	rs765485196	L1643L	0.51
BLCA	chr1	214644591	Nonsense_Mutation	novel	S1674*	0.1
BLCA	chr1	214632480	Missense_Mutation	novel	L442F	0.32
BLCA	chr1	214655348	Silent	novel	E2810E	0.11
BLCA	chr1	214622212	Silent	novel	E333E	0.13
BLCA	chr1	214605740	Intron	novel		0.23
BLCA	chr1	214643322	Missense_Mutation	novel	D1662H	0.18
BLCA	chr1	214658962	Silent	novel	L3025L	0.17
BLCA	chr1	214646677	Silent	novel	L2369L	0.32
BLCA	chr1	214651722	Missense_Mutation	NA	E2666Q	0.69
BLCA	chr1	214640989	Missense_Mutation	rs763766300	R884H	0.25
BLCA	chr1	214643030	Silent	novel	E1564E	0.5
BLCA	chr1	214645950	Missense_Mutation	NA	R2127H	0.41
BLCA	chr1	214641477	Frame_Shift_Del	novel	*Q1047Rfs7**	0.19
BLCA	chr1	214640022	Missense_Mutation	NA	D562H	0.21
BLCA	chr1	214652884	Silent	NA	L2739L	0.21
BLCA	chr1	214646639	Missense_Mutation	novel	L2357V	0.37
BLCA	chr1	214652889	Missense_Mutation	rs766558554	S2741L	0.5
BLCA	chr1	214620767	Missense_Mutation	NA	S229L	0.65
BLCA	chr1	214663719	Silent	rs533012183	V3090V	0.2
BLCA	chr1	214646240	Missense_Mutation	rs375601206	G2224S	0.25
BLCA	chr1	214652876	Missense_Mutation	novel	E2737Q	0.24
BLCA	chr1	214641221	Silent	NA	I961I	0.21
BLCA	chr1	214637903	Missense_Mutation	novel	S495C	0.38
BLCA	chr1	214644982	Missense_Mutation	novel	M1804I	0.15
BLCA	chr1	214639935	Nonsense_Mutation	NA	Q533*	0.4
BLCA	chr1	214641387	Nonsense_Mutation	NA	Q1017*	0.16
BLCA	chr1	214632554	Silent	rs139822426	A466A	0.08
BLCA	chr1	214642146	Missense_Mutation	novel	E1270K	0.06
BLCA	chr1	214656959	Missense_Mutation	novel	E2838K	0.2
BLCA	chr1	214663869	3'UTR	novel		0.14
BLCA	chr1	214646269	Silent	rs149273910	L2233L	0.24
BRCA	chr1	214605805	Intron	novel		0.17
BRCA	chr1	214620911	Missense_Mutation	novel	P277L	0.1
BRCA	chr1	214642111	Missense_Mutation	novel	I1258T	0.57
BRCA	chr1	214646157	Missense_Mutation	NA	R2196K	0.36
BRCA	chr1	214630585	Missense_Mutation	NA	Q416K	0.21
BRCA	chr1	214658848	Splice_Site	novel	X2988_splice	0.21
BRCA	chr1	214630576	Nonsense_Mutation	novel	E413*	0.08
BRCA	chr1	214644826	Frame_Shift_Del	novel	*P1754Tfs13**	0.09
BRCA	chr1	214642159	Missense_Mutation	rs746908378	S1274L	0.34
BRCA	chr1	214640812	Missense_Mutation	NA	S825F	0.18
BRCA	chr1	214645664	Missense_Mutation	novel	H2032D	0.09
BRCA	chr1	214613795	Missense_Mutation	novel	T14I	0.04
BRCA	chr1	214622151	Missense_Mutation	NA	N313S	0.22
BRCA	chr1	214641311	Missense_Mutation	NA	M991I	0.19
BRCA	chr1	214642284	Missense_Mutation	NA	E1316K	0.26
BRCA	chr1	214608469	Intron	novel		0.2
BRCA	chr1	214642682	Silent	NA	V1448V	0.12
BRCA	chr1	214605805	Intron	novel		0.41
BRCA	chr1	214641373	Missense_Mutation	NA	S1012L	0.12
BRCA	chr1	214641383	Frame_Shift_Del	novel	*D1016Ffs6**	0.08
BRCA	chr1	214642976	Silent	rs564882822	A1546A	0.39
BRCA	chr1	214645554	Missense_Mutation	NA	Q1995P	0.31
BRCA	chr1	214620879	Silent	NA	A266A	0.52
BRCA	chr1	214642921	Frame_Shift_Ins	novel	*S1529Vfs23**	0.17
BRCA	chr1	214640217	Missense_Mutation	rs555088086	E627K	0.11
BRCA	chr1	214663697	Missense_Mutation	novel	S3083N	0.09
CESC	chr1	214614835	Missense_Mutation	novel	E56K	0.14
CESC	chr1	214647134	Missense_Mutation	novel	E2522K	0.55
CESC	chr1	214642754	Silent	NA	L1472L	0.28
CESC	chr1	214657286	Missense_Mutation	novel	P2947S	0.17
CESC	chr1	214651831	Missense_Mutation	novel	R2702Q	0.16
CESC	chr1	214619152	Nonsense_Mutation	NA	E169*	0.41
CESC	chr1	214656980	Nonsense_Mutation	NA	E2845*	0.31
CESC	chr1	214646435	Missense_Mutation	NA	L2289V	0.36
CESC	chr1	214645960	Silent	rs200126499	A2130A	0.22
CESC	chr1	214605671	Intron	novel		0.32
CESC	chr1	214608479	Intron	novel		0.45
CESC	chr1	214613774	Missense_Mutation	novel	E7G	0.51
CESC	chr1	214614973	Missense_Mutation	novel	G102R	0.28
CESC	chr1	214639927	Missense_Mutation	novel	N530T	0.48
CESC	chr1	214641101	Missense_Mutation	novel	E921D	0.22
CESC	chr1	214641563	Silent	novel	K1075K	0.41
CESC	chr1	214642425	Missense_Mutation	novel	D1363Y	0.39
CESC	chr1	214646306	Missense_Mutation	NA	A2246S	0.2
CESC	chr1	214647343	Missense_Mutation	novel	K2591N	0.1
CESC	chr1	214645429	Silent	NA	L1953L	0.31
CESC	chr1	214608748	Intron	novel		0.12
CESC	chr1	214620939	Missense_Mutation	novel	Q286H	0.53
CESC	chr1	214622204	Nonsense_Mutation	novel	E331*	0.22
CESC	chr1	214645619	Nonsense_Mutation	novel	Q2017*	0.17
CESC	chr1	214645815	Missense_Mutation	novel	S2082L	0.22
CESC	chr1	214640276	Missense_Mutation	novel	H646Q	0.14
CESC	chr1	214637946	Silent	novel	L509L	0.24
CESC	chr1	214642687	Nonsense_Mutation	novel	S1450*	0.09
CESC	chr1	214642858	Missense_Mutation	NA	S1507C	0.32
CESC	chr1	214640316	Missense_Mutation	NA	E660K	0.59
CESC	chr1	214640961	Missense_Mutation	NA	Q875E	0.58
CHOL	chr1	214643273	Silent	NA	L1645L	0.31
COAD	chr1	214640325	Missense_Mutation	novel	E663K	0.42
COAD	chr1	214641636	Missense_Mutation	novel	M1100V	0.37
COAD	chr1	214642513	Missense_Mutation	novel	H1392L	0.09
COAD	chr1	214644591	Missense_Mutation	NA	S1674L	0.39
COAD	chr1	214629105	Missense_Mutation	NA	Q376H	0.2
COAD	chr1	214641928	Missense_Mutation	NA	E1197A	0.31
COAD	chr1	214642148	Silent	NA	E1270E	0.39
COAD	chr1	214645456	Silent	NA	Q1962Q	0.44
COAD	chr1	214647072	Missense_Mutation	NA	S2501Y	0.41
COAD	chr1	214608528	Intron	novel		0.21
COAD	chr1	214663650	Silent	rs148637528	T3067T	0.21
COAD	chr1	214646095	Silent	novel	L2175L	0.33
COAD	chr1	214641485	Missense_Mutation	NA	K1049N	0.38
COAD	chr1	214641892	Missense_Mutation	novel	R1185K	0.08
COAD	chr1	214642565	Missense_Mutation	NA	E1409D	0.36
COAD	chr1	214651850	Missense_Mutation	novel	K2708N	0.35
COAD	chr1	214608597	Intron	novel		0.4
COAD	chr1	214641691	Missense_Mutation	rs375681596	Q1118R	0.11
COAD	chr1	214622132	Nonsense_Mutation	NA	E307*	0.04
COAD	chr1	214641867	Missense_Mutation	novel	S1177A	0.12
COAD	chr1	214657094	Missense_Mutation	novel	T2883S	0.39
COAD	chr1	214614953	Frame_Shift_Del	NA	*Q96Sfs23**	0.34
COAD	chr1	214645047	Missense_Mutation	novel	I1826T	0.23
COAD	chr1	214647182	Missense_Mutation	novel	V2538L	0.36
COAD	chr1	214655330	Silent	novel	Q2804Q	0.25
COAD	chr1	214608366	Intron	novel		0.3
COAD	chr1	214640038	Missense_Mutation	novel	R567Q	0.12
COAD	chr1	214645880	Missense_Mutation	NA	A2104T	0.34
COAD	chr1	214620708	Silent	NA	R209R	0.31
COAD	chr1	214643230	Missense_Mutation	rs769388025	T1631M	0.08
COAD	chr1	214605853	Intron	novel		0.33
COAD	chr1	214622077	Splice_Site	novel	X289_splice	0.08
COAD	chr1	214646183	Missense_Mutation	rs754191320	L2205F	0.34
COAD	chr1	214645483	Frame_Shift_Del	NA	*T1974Pfs11**	0.22
COAD	chr1	214608733	Intron	novel		0.67
COAD	chr1	214608685	Intron	novel		0.31
COAD	chr1	214646131	Frame_Shift_Del	novel	*T2189Hfs3**	0.28
COAD	chr1	214642976	Silent	rs564882822	A1546A	0.23
COAD	chr1	214615018	Missense_Mutation	NA	E117K	0.18
COAD	chr1	214640672	Missense_Mutation	novel	E778D	0.13
COAD	chr1	214645449	Missense_Mutation	NA	R1960I	0.2
COAD	chr1	214657001	Nonsense_Mutation	novel	E2852*	0.1
COAD	chr1	214657310	Frame_Shift_Del	NA	*S2957Afs6**	0.52
COAD	chr1	214642368	Missense_Mutation	NA	N1344H	0.37
COAD	chr1	214642766	Silent	novel	L1476L	0.37
COAD	chr1	214641588	Nonsense_Mutation	NA	E1084*	0.32
COAD	chr1	214645950	Missense_Mutation	NA	R2127H	0.18
COAD	chr1	214646169	Missense_Mutation	NA	V2200A	0.41
COAD	chr1	214641378	Silent	NA	L1014L	0.3
COAD	chr1	214646674	Silent	NA	T2368T	0.28
COAD	chr1	214620797	Missense_Mutation	NA	R239K	0.29
COAD	chr1	214645691	Missense_Mutation	NA	E2041K	0.19
COAD	chr1	214647377	Missense_Mutation	NA	D2603N	0.25
COAD	chr1	214641223	Missense_Mutation	NA	I962S	0.21
COAD	chr1	214608538	Intron	novel		0.18
COAD	chr1	214618650	Frame_Shift_Del	novel	*I148Ffs6**	0.35
COAD	chr1	214613897	Missense_Mutation	novel	L48P	0.27
ESCA	chr1	214608603	Intron	novel		0.31
ESCA	chr1	214640898	Nonsense_Mutation	novel	E854*	0.07
ESCA	chr1	214620856	Missense_Mutation	novel	L259V	0.26
ESCA	chr1	214641406	Missense_Mutation	novel	L1023R	0.14
ESCA	chr1	214651872	Missense_Mutation	novel	D2716N	0.08
ESCA	chr1	214605944	Intron	novel		0.2
ESCA	chr1	214615030	Splice_Region	novel		0.05
ESCA	chr1	214642825	Frame_Shift_Del	novel	*A1498Qfs7**	0.16
ESCA	chr1	214629112	Missense_Mutation	novel	E379K	0.29
GBM	chr1	214646636	Missense_Mutation	NA	A2356T	0.3
GBM	chr1	214642746	Missense_Mutation	NA	E1470K	0.44
GBM	chr1	214641033	Missense_Mutation	novel	V899F	0.07
GBM	chr1	214645835	Missense_Mutation	rs754606834	V2089I	0.45
GBM	chr1	214645919	Silent	novel	L2117L	0.08
GBM	chr1	214642689	Missense_Mutation	novel	T1451A	0.04
GBM	chr1	214642493	Silent	rs139914723	D1385D	0.33
GBM	chr1	214605833	Intron	novel		0.26
GBM	chr1	214620697	Missense_Mutation	rs376653860	D206N	0.41
GBM	chr1	214646104	Missense_Mutation	novel	E2178D	0.22
GBM	chr1	214646317	Missense_Mutation	novel	Q2249H	0.19
GBM	chr1	214646426	Nonsense_Mutation	rs778236318	E2286*	0.24
GBM	chr1	214655339	Missense_Mutation	novel	E2807D	0.23
GBM	chr1	214656944	Missense_Mutation	novel	D2833N	0.2
GBM	chr1	214644866	Nonsense_Mutation	novel	Q1766*	0.1
GBM	chr1	214642411	Missense_Mutation	novel	G1358A	0.41
GBM	chr1	214642787	Missense_Mutation	novel	D1483E	0.5
GBM	chr1	214620741	Missense_Mutation	novel	Q220H	0.22
GBM	chr1	214663632	Silent	novel	I3061I	0.19
GBM	chr1	214663729	Nonsense_Mutation	NA	R3094*	0.76
GBM	chr1	214640194	Missense_Mutation	rs770366150	F619S	0.16
GBM	chr1	214641593	Missense_Mutation	novel	F1085L	0.19
GBM	chr1	214642615	Missense_Mutation	novel	C1426F	0.19
GBM	chr1	214645330	Silent	novel	Y1920Y	0.44
GBM	chr1	214646776	Missense_Mutation	novel	Q2402H	0.45
GBM	chr1	214657000	Silent	novel	E2851E	0.1
GBM	chr1	214613810	Missense_Mutation	NA	K19R	0.36
GBM	chr1	214658932	Silent	novel	L3015L	0.05
GBM	chr1	214605728	Intron	novel		0.67
HNSC	chr1	214645431	Missense_Mutation	NA	S1954L	0.17
HNSC	chr1	214651766	Silent	novel	C2680C	0.26
HNSC	chr1	214645664	Missense_Mutation	novel	H2032Y	0.06
HNSC	chr1	214605813	Intron	novel		0.34
HNSC	chr1	214657221	Frame_Shift_Del	novel	*N2926Ifs37**	0.27
HNSC	chr1	214641831	Missense_Mutation	novel	E1165Q	0.23
HNSC	chr1	214652950	Missense_Mutation	novel	K2761N	0.18
HNSC	chr1	214618593	Missense_Mutation	novel	R127T	0.44
HNSC	chr1	214646873	Frame_Shift_Ins	novel	*K2448Ifs17**	0.18
HNSC	chr1	214657143	Missense_Mutation	novel	G2899E	0.25
HNSC	chr1	214642769	Silent	novel	S1477S	0.33
HNSC	chr1	214642660	Missense_Mutation	novel	S1441L	0.25
HNSC	chr1	214640028	Nonsense_Mutation	novel	E564*	0.14
HNSC	chr1	214646004	Missense_Mutation	novel	R2145H	0.88
KIRC	chr1	214651830	Missense_Mutation	rs376987914	R2702W	0.38
KIRC	chr1	214640337	Missense_Mutation	NA	T667P	0.21
KIRC	chr1	214642354	Missense_Mutation	novel	V1339G	0.22
KIRC	chr1	214646356	Silent	NA	Q2262Q	0.27
KIRC	chr1	214640128	Missense_Mutation	novel	A597V	0.2
KIRC	chr1	214657060	Silent	NA	H2871H	0.29
KIRC	chr1	214643013	Missense_Mutation	rs764497035	Y1559H	0.08
KIRC	chr1	214645223	Missense_Mutation	NA	N1885Y	0.3
KIRC	chr1	214645548	Missense_Mutation	NA	S1993C	0.23
KIRP	chr1	214640205	Nonsense_Mutation	NA	K623*	0.4
KIRP	chr1	214652904	Missense_Mutation	NA	I2746T	0.21
KIRP	chr1	214646618	Missense_Mutation	novel	T2350A	0.34
KIRP	chr1	214642276	Missense_Mutation	NA	E1313V	0.49
KIRP	chr1	214647353	Missense_Mutation	NA	N2595Y	0.41
KIRP	chr1	214646222	Frame_Shift_Del	novel	*Q2218Kfs12**	0.84
KIRP	chr1	214658930	Missense_Mutation	novel	L3015M	0.23
KIRP	chr1	214629093	Silent	novel	S372S	0.04
LAML	chr1	214651783	Frame_Shift_Del	novel	*V2686Gfs7**	0.06
LAML	chr1	214646465	Missense_Mutation	NA	L2299V	0.48
LAML	chr1	214643117	Missense_Mutation	novel	Q1593H	0.13
LAML	chr1	214642313	Silent	novel	R1325R	0.45
LGG	chr1	214620936	Silent	rs114104425	A285A	0.19
LGG	chr1	214605752	Intron	novel		0.36
LGG	chr1	214608733	Intron	novel		0.67
LGG	chr1	214618585	Missense_Mutation	novel	E124D	0.46
LGG	chr1	214620695	Missense_Mutation	rs756993344	R205H	0.19
LGG	chr1	214638003	Splice_Site	rs374131527	X528_splice	0.39
LGG	chr1	214644782	Nonsense_Mutation	novel	K1738*	0.4
LGG	chr1	214618673	Frame_Shift_Ins	novel	*T154Rfs16**	0.08
LIHC	chr1	214643042	Missense_Mutation	NA	E1568D	0.27
LIHC	chr1	214642782	Missense_Mutation	novel	P1482S	0.36
LIHC	chr1	214608623	Intron	novel		0.35
LIHC	chr1	214645578	Missense_Mutation	NA	Q2003L	0.82
LIHC	chr1	214637922	Missense_Mutation	novel	E501D	0.05
LIHC	chr1	214644681	Missense_Mutation	novel	L1704P	0.39
LIHC	chr1	214640772	Missense_Mutation	novel	S812R	0.14
LIHC	chr1	214648741	Missense_Mutation	novel	A2633T	0.23
LUAD	chr1	214655276	Silent	NA	K2786K	0.15
LUAD	chr1	214663590	Splice_Site	NA	X3048_splice	0.54
LUAD	chr1	214645632	Missense_Mutation	rs762653487	S2021C	0.13
LUAD	chr1	214645632	Missense_Mutation	novel	S2021F	0.07
LUAD	chr1	214644851	Missense_Mutation	NA	D1761H	0.26
LUAD	chr1	214642879	Missense_Mutation	NA	G1514V	0.16
LUAD	chr1	214630560	Missense_Mutation	novel	F407L	0.19
LUAD	chr1	214641475	Missense_Mutation	NA	A1046V	0.17
LUAD	chr1	214642071	Missense_Mutation	NA	L1245F	0.16
LUAD	chr1	214644932	Missense_Mutation	NA	H1788Y	0.16
LUAD	chr1	214645429	Silent	NA	L1953L	0.16
LUAD	chr1	214645431	Missense_Mutation	NA	S1954L	0.16
LUAD	chr1	214646315	Missense_Mutation	NA	Q2249K	0.17
LUAD	chr1	214651806	Missense_Mutation	NA	E2694Q	0.21
LUAD	chr1	214652900	Missense_Mutation	rs747975726	E2745K	0.13
LUAD	chr1	214645667	Missense_Mutation	novel	L2033V	0.05
LUAD	chr1	214641887	Missense_Mutation	novel	S1183R	0.08
LUAD	chr1	214644817	Silent	novel	L1749L	0.13
LUAD	chr1	214622142	Missense_Mutation	novel	G310V	0.14
LUAD	chr1	214647969	Intron	novel		0.22
LUAD	chr1	214608694	Intron	novel		0.29
LUAD	chr1	214614887	Missense_Mutation	novel	M73T	0.06
LUAD	chr1	214640515	Missense_Mutation	NA	S726C	0.17
LUAD	chr1	214640873	Missense_Mutation	NA	M845I	0.08
LUAD	chr1	214614932	Missense_Mutation	novel	H88L	0.13
LUAD	chr1	214605869	Intron	novel		0.62
LUAD	chr1	214643263	Missense_Mutation	novel	R1642L	0.11
LUAD	chr1	214646535	Missense_Mutation	NA	Q2322P	0.05
LUAD	chr1	214643182	Missense_Mutation	novel	S1615N	0.59
LUAD	chr1	214618618	Silent	NA	A135A	0.14
LUAD	chr1	214614954	Silent	NA	S95S	0.1
LUAD	chr1	214637892	Silent	novel	L491L	0.08
LUAD	chr1	214645501	Silent	NA	L1977L	0.17
LUAD	chr1	214645502	Missense_Mutation	novel	D1978Y	0.17
LUAD	chr1	214640909	Silent	novel	V857V	0.27
LUAD	chr1	214646714	Missense_Mutation	rs779258589	G2382S	0.16
LUAD	chr1	214640397	Missense_Mutation	novel	D687Y	0.24
LUAD	chr1	214630647	Missense_Mutation	NA	Q436H	0.19
LUAD	chr1	214629085	Missense_Mutation	novel	D370N	0.26
LUAD	chr1	214645265	Missense_Mutation	NA	D1899H	0.22
LUAD	chr1	214645580	Missense_Mutation	novel	V2004L	0.26
LUAD	chr1	214640261	Missense_Mutation	NA	Q641H	0.05
LUAD	chr1	214656995	Missense_Mutation	NA	L2850F	0.2
LUAD	chr1	214644670	Missense_Mutation	NA	Q1700H	0.24
LUAD	chr1	214656949	Silent	NA	T2834T	0.18
LUAD	chr1	214646012	Nonsense_Mutation	NA	E2148*	0.45
LUAD	chr1	214645130	Nonsense_Mutation	novel	Q1854*	0.33
LUAD	chr1	214642746	Missense_Mutation	NA	E1470Q	0.3
LUAD	chr1	214642735	Missense_Mutation	NA	L1466P	0.14
LUAD	chr1	214645522	Missense_Mutation	NA	M1984I	0.44
LUAD	chr1	214620696	Silent	rs780975553	R205R	0.04
LUAD	chr1	214648712	Missense_Mutation	novel	R2623K	0.28
LUAD	chr1	214646254	Silent	novel	E2228E	0.12
LUAD	chr1	214642619	Silent	NA	Q1427Q	0.09
LUAD	chr1	214645133	Nonsense_Mutation	NA	E1855*	0.12
LUAD	chr1	214629078	Silent	novel	L367L	0.13
LUAD	chr1	214605854	Intron	novel		0.59
LUAD	chr1	214658950	Silent	novel	A3021A	0.13
LUAD	chr1	214643273	Silent	NA	L1645L	0.08
LUAD	chr1	214648768	Nonsense_Mutation	NA	E2642*	0.29
LUAD	chr1	214642032	Nonsense_Mutation	NA	E1232*	0.15
LUAD	chr1	214647109	Silent	novel	G2513G	0.42
LUAD	chr1	214658928	Missense_Mutation	novel	R3014L	0.19
LUAD	chr1	214652935	Silent	novel	L2756L	0.04
LUAD	chr1	214613791	Missense_Mutation	novel	P13A	0.41
LUAD	chr1	214641293	Silent	rs751726847	S985S	0.36
LUAD	chr1	214614945	Silent	NA	V92V	0.21
LUAD	chr1	214658956	Silent	NA	S3023S	0.3
LUSC	chr1	214637873	Missense_Mutation	novel	K485R	0.4
LUSC	chr1	214608631	Intron	novel		0.19
LUSC	chr1	214642128	Missense_Mutation	novel	C1264G	0.26
LUSC	chr1	214647215	Missense_Mutation	rs199813442	Q2549K	0.19
LUSC	chr1	214640260	Missense_Mutation	NA	Q641R	0.3
LUSC	chr1	214605953	Intron	novel		0.24
LUSC	chr1	214640474	Missense_Mutation	novel	Q712H	0.07
LUSC	chr1	214632603	Splice_Site	NA	X482_splice	0.34
LUSC	chr1	214642938	Nonsense_Mutation	NA	E1534*	0.14
LUSC	chr1	214637962	Missense_Mutation	NA	C515G	0.39
LUSC	chr1	214605971	Intron	novel		0.32
LUSC	chr1	214637946	Silent	novel	L509L	0.19
LUSC	chr1	214652885	Missense_Mutation	NA	S2740C	0.47
LUSC	chr1	214605681	Intron	NA		0.5
LUSC	chr1	214644635	Missense_Mutation	NA	D1689Y	0.27
LUSC	chr1	214605873	Intron	novel		0.3
LUSC	chr1	214645728	Missense_Mutation	novel	E2053G	0.46
LUSC	chr1	214651730	Silent	novel	T2668T	0.65
LUSC	chr1	214613778	Nonsense_Mutation	novel	W8*	0.42
LUSC	chr1	214641105	Missense_Mutation	novel	E923K	0.49
LUSC	chr1	214642718	Missense_Mutation	novel	L1460F	0.11
LUSC	chr1	214657085	Missense_Mutation	NA	M2880V	0.4
LUSC	chr1	214608648	Intron	novel		0.26
LUSC	chr1	214642637	Silent	novel	S1433S	0.32
LUSC	chr1	214641743	Missense_Mutation	novel	L1135F	0.73
LUSC	chr1	214613806	Nonsense_Mutation	NA	Q18*	0.28
LUSC	chr1	214657079	Missense_Mutation	novel	K2878E	0.58
LUSC	chr1	214646250	Nonsense_Mutation	novel	S2227*	0.58
LUSC	chr1	214641915	Missense_Mutation	novel	Q1193E	0.35
LUSC	chr1	214614902	Missense_Mutation	novel	S78N	0.19
LUSC	chr1	214618621	Missense_Mutation	novel	D136E	0.28
LUSC	chr1	214643296	Missense_Mutation	novel	R1653L	0.3
LUSC	chr1	214645234	Missense_Mutation	novel	K1888N	0.25
LUSC	chr1	214605950	Intron	novel		0.22
LUSC	chr1	214642336	Missense_Mutation	novel	R1333K	0.03
MESO	chr1	214646682	Frame_Shift_Ins	novel	*I2373Nfs28**	0.7
MESO	chr1	214640634	Silent	novel	L766L	0.32
OV	chr1	214614863	Missense_Mutation	novel	L65Q	0.11
OV	chr1	214641879	Frame_Shift_Del	rs567266370	*E1182Vfs21**	0.46
OV	chr1	214647157	Missense_Mutation	NA	N2529K	0.32
OV	chr1	214639959	Nonsense_Mutation	NA	Q541*	0.23
OV	chr1	214640523	Missense_Mutation	NA	T729S	0.13
OV	chr1	214608439	Intron	novel		0.47
OV	chr1	214640204	Nonsense_Mutation	NA	W622*	0.28
OV	chr1	214642179	Missense_Mutation	NA	T1281A	0.58
OV	chr1	214614839	Missense_Mutation	novel	N57I	0.31
OV	chr1	214614842	Frame_Shift_Del	novel	*T60Pfs6**	0.33
OV	chr1	214641706	Missense_Mutation	rs759811640	S1123N	0.42
OV	chr1	214643066	Missense_Mutation	novel	M1576I	0.21
OV	chr1	214622131	Silent	NA	K306K	0.33
OV	chr1	214642236	Silent	NA	L1300L	0.35
OV	chr1	214608662	Intron	novel		0.53
PAAD	chr1	214658963	Missense_Mutation	novel	S3026C	0.03
PAAD	chr1	214605668	Intron	novel		0.09
PAAD	chr1	214605789	Intron	novel		0.24
PAAD	chr1	214640613	Missense_Mutation	rs767318356	E759K	0.06
PAAD	chr1	214642107	Nonsense_Mutation	novel	E1257*	0.15
PAAD	chr1	214645132	Missense_Mutation	novel	Q1854H	0.18
PAAD	chr1	214646283	Missense_Mutation	novel	S2238N	0.15
PRAD	chr1	214637934	Silent	novel	L505L	0.43
PRAD	chr1	214605986	Intron	novel		0.1
PRAD	chr1	214606013	Intron	novel		0.4
PRAD	chr1	214608685	Intron	novel		0.26
PRAD	chr1	214605914	Intron	NA		0.3
PRAD	chr1	214646196	Missense_Mutation	novel	R2209M	0.34
PRAD	chr1	214652852	Nonsense_Mutation	novel	R2729*	0.13
READ	chr1	214608343	Intron	novel		0.2
READ	chr1	214620697	Missense_Mutation	rs376653860	D206N	0.18
READ	chr1	214641429	Missense_Mutation	NA	E1031K	0.29
READ	chr1	214642967	Silent	rs750577856	S1543S	0.28
READ	chr1	214656980	Nonsense_Mutation	NA	E2845*	0.22
READ	chr1	214643295	Missense_Mutation	rs569229505	R1653W	0.41
READ	chr1	214639954	In_Frame_Del	novel	L540_N545del	0.13
READ	chr1	214645610	Missense_Mutation	novel	E2014K	0.17
READ	chr1	214645483	Frame_Shift_Del	NA	*T1974Pfs11**	0.09
READ	chr1	214642966	Missense_Mutation	rs141012292	S1543L	0.21
READ	chr1	214608578	Intron	novel		0.26
READ	chr1	214652927	Nonsense_Mutation	NA	E2754*	0.2
READ	chr1	214641059	Missense_Mutation	novel	E907D	0.38
READ	chr1	214642244	Missense_Mutation	novel	E1302D	0.4
READ	chr1	214642976	Silent	rs564882822	A1546A	0.51
READ	chr1	214656989	Nonsense_Mutation	novel	E2848*	0.4
READ	chr1	214659018	Missense_Mutation	novel	R3044I	0.37
READ	chr1	214663899	3'UTR	novel		0.32
READ	chr1	214644696	Missense_Mutation	NA	I1709T	0.27
READ	chr1	214613724	5'UTR	rs111454498		0.21
READ	chr1	214614981	Silent	rs139296855	L104L	0.45
READ	chr1	214620931	Missense_Mutation	NA	K284Q	0.43
READ	chr1	214641485	Missense_Mutation	NA	K1049N	0.37
READ	chr1	214642691	Silent	rs765021891	T1451T	0.37
READ	chr1	214648770	Missense_Mutation	novel	E2642D	0.07
SARC	chr1	214605540	Intron	novel		0.15
SARC	chr1	214620706	Missense_Mutation	rs148125567	R209W	0.48
SARC	chr1	214641889	Missense_Mutation	novel	E1184G	0.3
SARC	chr1	214605546	Intron	novel		0.11
SARC	chr1	214655403	Missense_Mutation	novel	G2829S	0.32
SKCM	chr1	214605841	Intron	novel		0.17
SKCM	chr1	214639948	Missense_Mutation	NA	L537S	0.32
SKCM	chr1	214645296	Missense_Mutation	rs763314217	S1909L	0.42
SKCM	chr1	214641700	Missense_Mutation	novel	S1121F	0.37
SKCM	chr1	214644856	Silent	NA	F1762F	0.36
SKCM	chr1	214644969	Nonsense_Mutation	novel	L1800*	0.44
SKCM	chr1	214642809	Missense_Mutation	rs745591609	G1491R	0.12
SKCM	chr1	214645615	Silent	NA	L2015L	0.23
SKCM	chr1	214618634	Missense_Mutation	NA	P141S	0.47
SKCM	chr1	214642028	Silent	NA	E1230E	0.14
SKCM	chr1	214645119	Missense_Mutation	NA	S1850F	0.13
SKCM	chr1	214639922	Splice_Region	rs751697296	A528A	0.45
SKCM	chr1	214605722	Intron	novel		0.31
SKCM	chr1	214639988	Silent	NA	S550S	0.3
SKCM	chr1	214640764	Missense_Mutation	NA	S809L	0.28
SKCM	chr1	214642470	Missense_Mutation	NA	P1378S	0.08
SKCM	chr1	214620788	Missense_Mutation	NA	P236L	0.45
SKCM	chr1	214644626	Missense_Mutation	NA	P1686S	0.2
SKCM	chr1	214645847	Missense_Mutation	NA	L2093V	0.17
SKCM	chr1	214629146	Missense_Mutation	novel	K390R	0.43
SKCM	chr1	214608761	Intron	novel		0.29
SKCM	chr1	214608547	Intron	novel		0.31
SKCM	chr1	214643144	Silent	novel	Y1602Y	0.47
SKCM	chr1	214644606	Missense_Mutation	NA	S1679L	0.28
SKCM	chr1	214646712	Missense_Mutation	NA	R2381K	0.59
SKCM	chr1	214632558	Nonsense_Mutation	NA	Q468*	0.36
SKCM	chr1	214608742	Intron	novel		0.21
SKCM	chr1	214608697	Intron	novel		0.5
SKCM	chr1	214613798	Missense_Mutation	NA	R15K	0.31
SKCM	chr1	214643129	Silent	NA	C1597C	0.28
SKCM	chr1	214641014	Silent	NA	T892T	0.23
SKCM	chr1	214644861	Missense_Mutation	novel	G1764E	0.22
SKCM	chr1	214644862	Silent	novel	G1764G	0.23
SKCM	chr1	214606064	Intron	novel		0.5
SKCM	chr1	214641217	Missense_Mutation	NA	S960F	0.6
SKCM	chr1	214608679	Intron	novel		0.44
SKCM	chr1	214640190	Silent	NA	L618L	0.12
SKCM	chr1	214643135	Silent	novel	R1599R	0.46
SKCM	chr1	214645934	Missense_Mutation	NA	E2122K	0.62
SKCM	chr1	214605774	Intron	novel		0.53
SKCM	chr1	214606027	Intron	novel		0.26
SKCM	chr1	214640851	Missense_Mutation	NA	S838L	0.22
SKCM	chr1	214645119	Missense_Mutation	NA	S1850F	0.24
SKCM	chr1	214642999	Missense_Mutation	NA	S1554F	0.35
SKCM	chr1	214620819	Missense_Mutation	novel	F246L	0.49
SKCM	chr1	214645984	Silent	rs755070987	I2138I	0.25
SKCM	chr1	214643268	Nonsense_Mutation	novel	Q1644*	0.19
SKCM	chr1	214642961	Silent	novel	T1541T	0.37
SKCM	chr1	214644874	Missense_Mutation	NA	D1768E	0.13
SKCM	chr1	214651795	Missense_Mutation	NA	G2690E	0.13
SKCM	chr1	214655320	Missense_Mutation	NA	S2801F	0.15
SKCM	chr1	214605847	Intron	NA		0.42
SKCM	chr1	214605848	Intron	novel		0.42
SKCM	chr1	214642159	Missense_Mutation	rs746908378	S1274L	0.13
SKCM	chr1	214640167	Missense_Mutation	NA	E610A	0.21
SKCM	chr1	214642662	Missense_Mutation	NA	L1442I	0.65
SKCM	chr1	214608686	Intron	novel		0.65
SKCM	chr1	214640385	Missense_Mutation	NA	H683Y	0.26
SKCM	chr1	214646331	Missense_Mutation	NA	S2254F	0.22
SKCM	chr1	214652956	Silent	NA	T2763T	0.11
SKCM	chr1	214657189	Silent	NA	P2914P	0.11
SKCM	chr1	214640303	Frame_Shift_Ins	novel	*I656Afs3**	0.07
SKCM	chr1	214657277	Missense_Mutation	novel	G2944R	0.34
SKCM	chr1	214608627	Intron	novel		0.11
STAD	chr1	214644675	Missense_Mutation	NA	L1702H	0.13
STAD	chr1	214618668	Missense_Mutation	NA	P152L	0.21
STAD	chr1	214645950	Missense_Mutation	NA	R2127H	0.2
STAD	chr1	214605950	Intron	novel		0.14
STAD	chr1	214605895	Intron	novel		0.39
STAD	chr1	214642096	Missense_Mutation	NA	M1253T	0.22
STAD	chr1	214645483	Frame_Shift_Del	NA	*T1974Pfs11**	0.15
STAD	chr1	214645608	Missense_Mutation	rs150986314	T2013M	0.16
STAD	chr1	214620842	Missense_Mutation	NA	P254Q	0.2
STAD	chr1	214645483	Frame_Shift_Del	NA	*T1974Pfs11**	0.13
STAD	chr1	214657310	Frame_Shift_Del	NA	*S2957Afs6**	0.38
STAD	chr1	214657099	Missense_Mutation	NA	Q2884H	0.33
STAD	chr1	214645961	Missense_Mutation	rs181293702	D2131N	0.09
STAD	chr1	214642489	Missense_Mutation	NA	L1384S	0.19
STAD	chr1	214622191	Missense_Mutation	NA	K326N	0.13
STAD	chr1	214620936	Silent	rs114104425	A285A	0.3
STAD	chr1	214657310	Frame_Shift_Del	NA	*S2957Afs6**	0.24
STAD	chr1	214608390	Intron	novel		0.42
STAD	chr1	214657310	Frame_Shift_Del	NA	*S2957Afs6**	0.36
STAD	chr1	214642966	Missense_Mutation	rs141012292	S1543L	0.4
STAD	chr1	214642922	Nonsense_Mutation	NA	C1528*	0.22
STAD	chr1	214640759	Missense_Mutation	NA	M807I	0.22
STAD	chr1	214620848	Missense_Mutation	rs147545168	R256Q	0.21
STAD	chr1	214629063	Missense_Mutation	NA	Q362H	0.3
STAD	chr1	214640631	Missense_Mutation	NA	D765N	0.19
STAD	chr1	214642565	Missense_Mutation	NA	E1409D	0.16
STAD	chr1	214642940	Missense_Mutation	NA	E1534D	0.27
STAD	chr1	214652858	Missense_Mutation	NA	K2731E	0.59
STAD	chr1	214646026	Silent	rs559968112	L2152L	0.35
STAD	chr1	214640497	Missense_Mutation	NA	N720I	0.17
STAD	chr1	214630621	Missense_Mutation	novel	A428S	0.26
STAD	chr1	214657310	Frame_Shift_Del	NA	*S2957Afs6**	0.44
STAD	chr1	214640525	Silent	NA	T729T	0.12
STAD	chr1	214642930	Missense_Mutation	NA	L1531P	0.27
STAD	chr1	214605951	Intron	novel		0.19
STAD	chr1	214640482	Missense_Mutation	NA	Q715R	0.2
STAD	chr1	214608784	Intron	novel		0.52
STAD	chr1	214641425	Silent	NA	C1029C	0.19
STAD	chr1	214619179	Nonsense_Mutation	rs199800194	R178*	0.42
STAD	chr1	214645483	Frame_Shift_Del	NA	*T1974Pfs11**	0.44
STAD	chr1	214645704	Missense_Mutation	NA	Q2045R	0.44
STAD	chr1	214606062	Intron	novel		0.14
STAD	chr1	214608366	Intron	novel		0.3
STAD	chr1	214646093	Missense_Mutation	NA	L2175I	0.48
STAD	chr1	214642490	Silent	NA	L1384L	0.17
STAD	chr1	214642474	Missense_Mutation	NA	V1379G	0.12
STAD	chr1	214645291	Silent	NA	I1907I	0.05
STAD	chr1	214608379	Intron	novel		0.41
STAD	chr1	214608396	Intron	novel		0.23
STAD	chr1	214605869	Intron	novel		0.18
STAD	chr1	214608685	Intron	novel		0.21
STAD	chr1	214608598	Intron	novel		0.19
STAD	chr1	214605848	Intron	novel		0.19
STAD	chr1	214618655	Frame_Shift_Ins	novel	*T150Yfs11**	0.15
STAD	chr1	214645581	Missense_Mutation	NA	V2004A	0.1
STAD	chr1	214652906	Missense_Mutation	NA	D2747Y	0.34
STAD	chr1	214657310	Frame_Shift_Del	NA	*S2957Afs6**	0.15
STAD	chr1	214605853	Intron	novel		0.14
STAD	chr1	214645705	Missense_Mutation	NA	Q2045H	0.45
STAD	chr1	214656937	Silent	novel	T2830T	0.06
STAD	chr1	214642391	Silent	NA	D1351D	0.14
STAD	chr1	214642670	Silent	rs372343987	A1444A	0.35
STAD	chr1	214658866	Silent	NA	P2993P	0.37
STAD	chr1	214646521	Missense_Mutation	NA	Q2317H	0.65
STAD	chr1	214645483	Frame_Shift_Del	NA	*T1974Pfs11**	0.11
STAD	chr1	214647379	Missense_Mutation	NA	D2603E	0.64
TGCT	chr1	214614857	Missense_Mutation	novel	T63R	0.25
THCA	chr1	214618673	Frame_Shift_Ins	novel	*T154Rfs18**	0.08
THCA	chr1	214618675	Frame_Shift_Ins	novel	*P155Ffs9**	0.04
THCA	chr1	214646762	Frame_Shift_Del	novel	*T2398Qfs14**	0.08
THCA	chr1	214646764	Frame_Shift_Del	novel	N2399*	0.08
THCA	chr1	214645209	Missense_Mutation	novel	E1880G	0.37
THCA	chr1	214663869	3'UTR	novel		0.13
THCA	chr1	214608821	Intron	novel		0.62
THCA	chr1	214651814	Frame_Shift_Ins	novel	*A2697Mfs31**	0.06
THYM	chr1	214648492	Intron	novel		0.08
UCEC	chr1	214608562	Intron	NA		0.5
UCEC	chr1	214640041	Missense_Mutation	novel	D568A	0.17
UCEC	chr1	214606076	Intron	novel		0.24
UCEC	chr1	214622132	Nonsense_Mutation	NA	E307*	0.05
UCEC	chr1	214640072	Missense_Mutation	NA	E578D	0.29
UCEC	chr1	214640931	Nonsense_Mutation	NA	E865*	0.29
UCEC	chr1	214641750	Missense_Mutation	NA	E1138K	0.33
UCEC	chr1	214655368	Missense_Mutation	NA	S2817C	0.5
UCEC	chr1	214620782	Missense_Mutation	NA	R234I	0.3
UCEC	chr1	214640613	Missense_Mutation	rs767318356	E759K	0.39
UCEC	chr1	214641080	Silent	rs773927067	Q914Q	0.23
UCEC	chr1	214642851	Missense_Mutation	NA	D1505Y	0.24
UCEC	chr1	214643042	Missense_Mutation	NA	E1568D	0.2
UCEC	chr1	214646327	Nonsense_Mutation	NA	E2253*	0.28
UCEC	chr1	214651776	Missense_Mutation	novel	D2684Y	0.12
UCEC	chr1	214613887	Missense_Mutation	rs368361514	E45K	0.46
UCEC	chr1	214614934	Nonsense_Mutation	novel	E89*	0.08
UCEC	chr1	214629154	Nonsense_Mutation	novel	E393*	0.08
UCEC	chr1	214645363	Missense_Mutation	NA	E1931D	0.37
UCEC	chr1	214648767	Silent	novel	G2641G	0.08
UCEC	chr1	214605914	Intron	NA		0.28
UCEC	chr1	214640718	Missense_Mutation	novel	H794Y	0.09
UCEC	chr1	214642967	Silent	rs750577856	S1543S	0.44
UCEC	chr1	214644979	Silent	rs762547802	E1803E	0.25
UCEC	chr1	214646003	Missense_Mutation	rs114218080	R2145C	0.36
UCEC	chr1	214646587	Missense_Mutation	novel	E2339D	0.35
UCEC	chr1	214646790	Missense_Mutation	rs764028137	R2407Q	0.48
UCEC	chr1	214642828	Missense_Mutation	NA	R1497I	0.19
UCEC	chr1	214643313	Missense_Mutation	rs779677155	D1659N	0.07
UCEC	chr1	214645348	Silent	NA	E1926E	0.21
UCEC	chr1	214651761	Missense_Mutation	NA	D2679N	0.42
UCEC	chr1	214663899	3'UTR	novel		0.67
UCEC	chr1	214657345	Frame_Shift_Del	novel	*P2967Lfs19**	0.12
UCEC	chr1	214608503	Intron	novel		0.48
UCEC	chr1	214644882	Missense_Mutation	novel	N1771T	0.43
UCEC	chr1	214648494	Intron	novel		0.39
UCEC	chr1	214658866	Silent	NA	P2993P	0.36
UCEC	chr1	214663650	Silent	rs148637528	T3067T	0.36
UCEC	chr1	214646104	Missense_Mutation	novel	E2178D	0.29
UCEC	chr1	214605627	Intron	novel		0.37
UCEC	chr1	214606029	Intron	novel		0.43
UCEC	chr1	214608349	Intron	novel		0.37
UCEC	chr1	214622149	Silent	novel	V312V	0.42
UCEC	chr1	214641079	Missense_Mutation	novel	Q914R	0.33
UCEC	chr1	214642452	Nonsense_Mutation	novel	Q1372*	0.31
UCEC	chr1	214658989	Silent	novel	E3034E	0.41
UCEC	chr1	214608622	Intron	novel		0.42
UCEC	chr1	214642849	Missense_Mutation	novel	G1504E	0.15
UCEC	chr1	214645766	Nonsense_Mutation	novel	E2066*	0.25
UCEC	chr1	214605802	Intron	novel		0.17
UCEC	chr1	214619169	Silent	NA	E174E	0.23
UCEC	chr1	214647319	Frame_Shift_Ins	novel	*E2584Kfs7**	0.12
UCEC	chr1	214622203	Silent	NA	I330I	0.42
UCEC	chr1	214606034	Intron	novel		0.13
UCEC	chr1	214614891	Missense_Mutation	NA	E74D	0.22
UCEC	chr1	214629081	Silent	rs754671280	T368T	0.09
UCEC	chr1	214640601	Frame_Shift_Ins	novel	*D755Vfs15**	0.12
UCEC	chr1	214641421	Missense_Mutation	NA	R1028I	0.24
UCEC	chr1	214645481	Missense_Mutation	NA	S1971T	0.12
UCEC	chr1	214645934	Missense_Mutation	NA	E2122K	0.17
UCEC	chr1	214646858	Missense_Mutation	NA	V2430L	0.38
UCEC	chr1	214618639	Silent	rs768336181	C142C	0.17
UCEC	chr1	214640202	Missense_Mutation	novel	W622R	0.22
UCEC	chr1	214641962	Silent	rs145854163	A1208A	0.13
UCEC	chr1	214642545	Missense_Mutation	rs146731847	H1403Y	0.32
UCEC	chr1	214658950	Silent	rs749594564	A3021A	0.2
UCEC	chr1	214605873	Intron	novel		0.17
UCEC	chr1	214613882	Missense_Mutation	NA	S43I	0.29
UCEC	chr1	214645091	Missense_Mutation	NA	D1841Y	0.39
UCEC	chr1	214646650	Missense_Mutation	NA	E2360D	0.36
UCEC	chr1	214618652	Missense_Mutation	novel	K147Q	0.22
UCEC	chr1	214645372	Silent	rs746565223	C1934C	0.33
UCEC	chr1	214651850	Missense_Mutation	NA	K2708N	0.18
UCEC	chr1	214644861	Missense_Mutation	novel	G1764E	0.57
UCEC	chr1	214641876	Nonsense_Mutation	novel	*E1180delinsVSQIRQDQ**	0.06
UCEC	chr1	214608348	Intron	novel		0.2
UCEC	chr1	214614992	Missense_Mutation	novel	K108T	0.26
UCEC	chr1	214630626	Missense_Mutation	NA	K429N	0.19
UCEC	chr1	214642565	Missense_Mutation	NA	E1409D	0.41
UCEC	chr1	214645449	Missense_Mutation	NA	R1960I	0.42
UCEC	chr1	214656980	Nonsense_Mutation	NA	E2845*	0.33
UCEC	chr1	214640805	Missense_Mutation	novel	K823Q	0.34
UCEC	chr1	214644916	Missense_Mutation	rs372338929	E1782D	0.35
UCEC	chr1	214655339	Missense_Mutation	novel	E2807D	0.13
UCEC	chr1	214657321	Missense_Mutation	novel	K2958N	0.48
UCEC	chr1	214663650	Silent	rs148637528	T3067T	0.14
UCEC	chr1	214608379	Intron	novel		0.11
UCEC	chr1	214637938	Missense_Mutation	novel	A507T	0.24
UCEC	chr1	214651856	Silent	rs778437405	H2710H	0.26
UCEC	chr1	214605601	Intron	novel		0.14
UCEC	chr1	214645460	Missense_Mutation	rs139947449	R1964C	0.31
UCEC	chr1	214642101	Missense_Mutation	novel	S1255P	0.31
UCEC	chr1	214605780	Intron	novel		0.39
UCEC	chr1	214608343	Intron	novel		0.33
UCEC	chr1	214643231	Silent	rs775136005	T1631T	0.83
UCEC	chr1	214641974	Missense_Mutation	novel	Q1212H	0.45
UCEC	chr1	214632578	Missense_Mutation	novel	E474D	0.49
UCEC	chr1	214641936	Nonsense_Mutation	novel	E1200*	0.57
UCEC	chr1	214645489	Missense_Mutation	novel	K1973N	0.59
UCEC	chr1	214642699	Missense_Mutation	NA	R1454I	0.3
UCEC	chr1	214605715	Intron	novel		0.44
UCEC	chr1	214641289	Missense_Mutation	novel	A984V	0.38
UCEC	chr1	214642624	Missense_Mutation	novel	S1429N	0.49
UCEC	chr1	214658877	Missense_Mutation	novel	T2997I	0.56
UCEC	chr1	214608343	Intron	novel		0.18
UCEC	chr1	214642142	Silent	rs755038430	A1268A	0.67
UCEC	chr1	214642509	Missense_Mutation	rs141352776	E1391K	0.44
UCEC	chr1	214647101	Nonsense_Mutation	novel	E2511*	0.48
UCEC	chr1	214655396	Missense_Mutation	novel	Q2826H	0.35
UCEC	chr1	214642422	Missense_Mutation	novel	E1362K	0.36
UCEC	chr1	214647356	Frame_Shift_Ins	novel	*E2596Vfs7**	0.27
UCEC	chr1	214645521	Missense_Mutation	rs61741924	M1984T	0.08
UCEC	chr1	214655294	Silent	rs373154133	Q2792Q	0.39
UCEC	chr1	214657040	Missense_Mutation	novel	C2865R	0.25
UCEC	chr1	214620854	Missense_Mutation	NA	T258I	0.27
UCEC	chr1	214641240	Nonsense_Mutation	novel	E968*	0.45
UCEC	chr1	214641655	Missense_Mutation	rs755394404	V1106A	0.56
UCEC	chr1	214651886	Splice_Region	novel	Q2720Q	0.1
UCEC	chr1	214641936	Nonsense_Mutation	novel	E1200*	0.47
UCEC	chr1	214645466	Nonsense_Mutation	NA	E1966*	0.67
UCEC	chr1	214646880	Missense_Mutation	novel	S2437I	0.31
UCEC	chr1	214605736	Intron	novel		0.31
UCEC	chr1	214618651	Missense_Mutation	novel	Q146H	0.41
UCEC	chr1	214639947	Silent	novel	L537L	0.13
UCEC	chr1	214640544	Nonsense_Mutation	novel	E736*	0.21
UCEC	chr1	214645170	Missense_Mutation	novel	N1867S	0.11
UCEC	chr1	214645766	Nonsense_Mutation	novel	E2066*	0.13
UCEC	chr1	214646780	Nonsense_Mutation	NA	E2404*	0.19
UCEC	chr1	214648756	Nonsense_Mutation	novel	E2638*	0.12
UCEC	chr1	214605618	Intron	novel		0.42
UCEC	chr1	214618656	Missense_Mutation	novel	I148N	0.41
UCEC	chr1	214640965	Missense_Mutation	novel	S876N	0.56
UCEC	chr1	214641128	Frame_Shift_Del	novel	*K932Rfs10**	0.37
UCEC	chr1	214605620	Intron	novel		0.18
UCEC	chr1	214657310	Frame_Shift_Del	NA	*S2957Afs6**	0.24
UCEC	chr1	214629138	Silent	novel	Q387Q	0.33
UCEC	chr1	214641936	Nonsense_Mutation	novel	E1200*	0.56
UCEC	chr1	214657084	Missense_Mutation	novel	E2879D	0.22
UCEC	chr1	214608343	Intron	novel		0.06
UCEC	chr1	214608672	Intron	novel		0.32
UCEC	chr1	214642691	Silent	rs765021891	T1451T	0.38
UCEC	chr1	214646587	Missense_Mutation	novel	E2339D	0.26
UCEC	chr1	214646458	Silent	NA	E2296E	0.53
UCEC	chr1	214646629	Silent	novel	E2353E	0.41
UCEC	chr1	214657105	Silent	novel	A2886A	0.44
UCEC	chr1	214645482	Frame_Shift_Ins	rs757531591	*T1974Nfs9**	0.3
UCEC	chr1	214642825	Missense_Mutation	NA	Y1496C	0.13
UCEC	chr1	214643308	Missense_Mutation	novel	G1657A	0.05
UCEC	chr1	214645990	Missense_Mutation	NA	E2140D	0.06
UCEC	chr1	214605517	Intron	novel		0.28
UCEC	chr1	214632563	Silent	novel	A469A	0.5
UCEC	chr1	214641238	Missense_Mutation	novel	R967M	0.39
UCEC	chr1	214618609	Silent	NA	A132A	0.32
UCEC	chr1	214641606	Missense_Mutation	NA	A1090S	0.08
UCEC	chr1	214608835	Intron	novel		0.29
UCEC	chr1	214605752	Intron	novel		0.29
UCEC	chr1	214618609	Silent	NA	A132A	0.18
UCEC	chr1	214637883	Silent	NA	N488N	0.18
UCEC	chr1	214658928	Missense_Mutation	novel	R3014H	0.04
UCEC	chr1	214646854	Missense_Mutation	NA	E2428D	0.38
UCEC	chr1	214656933	Missense_Mutation	novel	G2829D	0.57
UCEC	chr1	214646582	Nonsense_Mutation	novel	*V2338Efs2**	0.1
UCEC	chr1	214657344	Frame_Shift_Ins	novel	*P2967Lfs11**	0.09
UCEC	chr1	214643042	Missense_Mutation	NA	E1568D	0.4
UCEC	chr1	214605951	Intron	novel		0.23
UCEC	chr1	214641356	Missense_Mutation	novel	E1006D	0.21
UCEC	chr1	214640114	Missense_Mutation	NA	E592D	0.48
UCEC	chr1	214640683	Missense_Mutation	NA	R782I	0.33
UCEC	chr1	214642699	Missense_Mutation	NA	R1454I	0.1
UCEC	chr1	214645303	Missense_Mutation	NA	K1911N	0.44
UCEC	chr1	214644986	Nonsense_Mutation	NA	E1806*	0.4
UCEC	chr1	214645984	Silent	rs755070987	I2138I	0.05
UCEC	chr1	214620782	Missense_Mutation	NA	R234I	0.19
UCEC	chr1	214645762	Silent	NA	E2064E	0.27
UCEC	chr1	214646062	Silent	NA	Q2164Q	0.22
UCEC	chr1	214614924	Missense_Mutation	NA	K85N	0.33
UCEC	chr1	214641991	Missense_Mutation	NA	R1218I	0.37
UCEC	chr1	214647139	Missense_Mutation	novel	E2523D	0.24
UCEC	chr1	214641485	Missense_Mutation	NA	K1049N	0.35
UCEC	chr1	214618667	Missense_Mutation	novel	P152S	0.18
UCEC	chr1	214620936	Silent	rs114104425	A285A	0.52
UCEC	chr1	214641761	Missense_Mutation	novel	K1141N	0.13
UCEC	chr1	214642428	Missense_Mutation	novel	I1364V	0.12
UCEC	chr1	214643231	Silent	rs775136005	T1631T	0.35
UCEC	chr1	214645232	Missense_Mutation	novel	K1888E	0.21
UCEC	chr1	214655303	Missense_Mutation	rs753288669	M2795I	0.35
UCEC	chr1	214657093	Missense_Mutation	novel	E2882D	0.11
UCEC	chr1	214658916	Missense_Mutation	rs753575219	R3010Q	0.31
UCEC	chr1	214645382	Missense_Mutation	rs776282020	D1938Y	0.41
UCEC	chr1	214645766	Nonsense_Mutation	novel	E2066*	0.54
UCEC	chr1	214606064	Intron	novel		0.07
UCEC	chr1	214608716	Intron	novel		0.21
UCEC	chr1	214640514	Missense_Mutation	novel	S726P	0.24
UCEC	chr1	214659018	Missense_Mutation	novel	R3044K	0.22
UCEC	chr1	214663813	3'UTR	novel		0.23
UCEC	chr1	214605871	Intron	novel		0.16
UCEC	chr1	214615028	Missense_Mutation	novel	R120M	0.11
UCEC	chr1	214618650	Frame_Shift_Del	novel	*I148Ffs6**	0.14
UCEC	chr1	214620886	Missense_Mutation	NA	S269G	0.16
UCEC	chr1	214630553	Missense_Mutation	rs761268475	R405H	0.19
UCEC	chr1	214641657	Nonsense_Mutation	NA	Q1107*	0.14
UCEC	chr1	214645501	Silent	NA	L1977L	0.18
UCEC	chr1	214645613	Missense_Mutation	novel	L2015F	0.06
UCEC	chr1	214651729	Missense_Mutation	NA	T2668I	0.13
UCEC	chr1	214652957	Missense_Mutation	novel	T2764P	0.07
UCEC	chr1	214663715	Missense_Mutation	novel	R3089M	0.09
UCEC	chr1	214663880	3'UTR	novel		0.24
UCEC	chr1	214605669	Intron	novel		0.39
UCEC	chr1	214642205	Silent	NA	L1289L	0.24
UCEC	chr1	214613868	Missense_Mutation	novel	Q38H	0.32
UCEC	chr1	214618609	Silent	NA	A132A	0.28
UCEC	chr1	214639980	Nonsense_Mutation	novel	E548*	0.47
UCEC	chr1	214641263	Silent	novel	E975E	0.47
UCEC	chr1	214642137	Missense_Mutation	novel	D1267N	0.3
UCEC	chr1	214644851	Missense_Mutation	novel	D1761N	0.36
UCEC	chr1	214655388	Missense_Mutation	novel	E2824K	0.47
UCEC	chr1	214663639	Nonsense_Mutation	novel	E3064*	0.43
UCEC	chr1	214605544	Intron	novel		0.33
UCEC	chr1	214608562	Intron	NA		0.31
UCEC	chr1	214645856	Missense_Mutation	rs371317728	A2096T	0.41
UCEC	chr1	214655330	Silent	novel	Q2804Q	0.35
UCS	chr1	214640931	Nonsense_Mutation	NA	E865*	0.32
UVM	chr1	214642777	Missense_Mutation	novel	C1480Y	0.5

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.0907	0.033566
DLBC	DEL	0.0625	0.0017831
GBM	DEL	0.0572	0.00056261
KIRC	DEL	0.0606	0.018371
LGG	DEL	0.0273	0.11599
OV	DEL	0.1313	0.18187
READ	AMP	0.2788	0.14328
SARC	DEL	0.2763	2.6086e-08
TGCT	DEL	0.02	0.16985
THCA	AMP	0.0481	0.075436
THYM	AMP	0.1789	0.24554

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0053	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.0078	Kaplan-Meier Survival Analysis
MESO	0.00012	Kaplan-Meier Survival Analysis
ACC	0.00013	Kaplan-Meier Survival Analysis
SKCM	0.0078	Kaplan-Meier Survival Analysis
KIRP	0.0001	Kaplan-Meier Survival Analysis
PAAD	0.00048	Kaplan-Meier Survival Analysis
PCPG	0.029	Kaplan-Meier Survival Analysis
KICH	0.01	Kaplan-Meier Survival Analysis
UCEC	0.0034	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.033	Kaplan-Meier Survival Analysis
LUAD	0.00012	Kaplan-Meier Survival Analysis
UVM	0.026	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000117724 (Gene tree)
Gene ID: 1063
Gene Symbol: CENPF
Alias: hcp-1
Full Name: centromere protein F
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 61,410 bases
Position: chr1:214,603,179-214,664,588
Accession: 1857
RBP type: non-canonical RBP
Summary: This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31339449	The Human- and Smooth Muscle Cell-Enriched lncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling.	Circ Res	2019 Jul 24	Mahmoud AD	doi: 10.1161/CIRCRESAHA.119.314876

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000495259	CENPF-205	345	-	-	- (aa)	-	-
ENST00000467765	CENPF-203	1427	-	-	- (aa)	-	-
ENST00000366955	CENPF-201	10307	XM_011509082	ENSP00000355922	3114 (aa)	XP_011507384	P49454
ENST00000614578	CENPF-206	528	-	ENSP00000478221	175 (aa)	-	A0A087WTY4
ENST00000469862	CENPF-204	734	-	-	- (aa)	-	-
ENST00000464322	CENPF-202	689	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000117724's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000117724	Lipoproteins, VLDL	1.37253127612943E-6	17903299
ENSG00000117724	Lipoproteins, VLDL	1.37253127612954E-6	17903299
ENSG00000117724	Lipoproteins, VLDL	2.36861733649133E-8	17903299
ENSG00000117724	Lipoproteins, VLDL	2.10980437176291E-8	17903299
ENSG00000117724	Lipoproteins, VLDL	2.10980437176284E-8	17903299
ENSG00000117724	Lipoproteins, VLDL	3.73253788472081E-8	17903299
ENSG00000117724	Lipoproteins, VLDL	1.44874025534459E-7	17903299
ENSG00000117724	Stroke	8.9298448E-004	-
ENSG00000117724	Stroke	8.4958802E-004	-
ENSG00000117724	Child Development Disorders, Pervasive	2.9000000E-005	-
ENSG00000117724	Antineoplastic Agents	5E-6	21659360
ENSG00000117724	Prostatic Neoplasms	2E-6	27515689
ENSG00000117724	Electromagnetic Radiation	2E-6	27515689

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000117724	rs438034	1	214657274	T	Response to antineoplastic agents	21659360	[1.44-2.46]	1.88	GO_0097327

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000117724's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000117724	CENPF	100	66.329	ENSMUSG00000026605	Cenpf	100	71.853	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000278	mitotic cell cycle	7542657.	IMP	Process
GO:0000775	chromosome, centromeric region	7542657.7651420.11084331.	IDA	Component
GO:0000776	kinetochore	7542657.9763420.17363900.	IDA	Component
GO:0000785	chromatin	9891037.	NAS	Component
GO:0000922	spindle pole	7542657.	IDA	Component
GO:0000940	condensed chromosome outer kinetochore	7542657.7642639.7904902.	IDA	Component
GO:0000940	condensed chromosome outer kinetochore	12974617.	TAS	Component
GO:0001822	kidney development	25564561.	IMP	Process
GO:0003682	chromatin binding	9891037.	NAS	Function
GO:0005515	protein binding	7651420.9763420.17043677.17363900.17600710.25564561.	IPI	Function
GO:0005634	nucleus	7542657.7642639.7651420.15494374.	IDA	Component
GO:0005635	nuclear envelope	12154071.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	12974617.	IDA	Component
GO:0005813	centrosome	-	IEA	Component
GO:0005819	spindle	7651420.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005930	axoneme	-	IEA	Component
GO:0007059	chromosome segregation	16252009.	IMP	Process
GO:0007059	chromosome segregation	7542657.	NAS	Process
GO:0007094	mitotic spindle assembly checkpoint	12974617.	NAS	Process
GO:0007517	muscle organ development	-	IEA	Process
GO:0008022	protein C-terminus binding	7642639.	IPI	Function
GO:0008134	transcription factor binding	15677469.	IPI	Function
GO:0008283	cell proliferation	12507285.15927522.	NAS	Process
GO:0010389	regulation of G2/M transition of mitotic cell cycle	7651420.12154071.	IMP	Process
GO:0015031	protein transport	12974617.	IDA	Process
GO:0015031	protein transport	17600710.	IMP	Process
GO:0016202	regulation of striated muscle tissue development	10373470.	ISS	Process
GO:0016363	nuclear matrix	7542657.	IDA	Component
GO:0021591	ventricular system development	25564561.	IMP	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0030496	midbody	7651420.	IDA	Component
GO:0036064	ciliary basal body	-	IEA	Component
GO:0042493	response to drug	12467231.	NAS	Process
GO:0042803	protein homodimerization activity	7642639.	IPI	Function
GO:0045120	pronucleus	-	IEA	Component
GO:0045892	negative regulation of transcription, DNA-templated	15677469.	IDA	Process
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component
GO:0051301	cell division	-	IEA	Process
GO:0051310	metaphase plate congression	15870278.	IDA	Process
GO:0051382	kinetochore assembly	16252009.	NAS	Process
GO:0051726	regulation of cell cycle	-	TAS	Process
GO:0070840	dynein complex binding	12974617.	IDA	Function
GO:0071897	DNA biosynthetic process	-	IEA	Process
GO:0097539	ciliary transition fiber	25564561.	IMP	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.