EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
18289367	A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study.	BMC Cancer	2008 Feb 20	Hansen RD	doi: 10.1186/1471-2407-8-54.
23624123	Effects of PPP1R13L and CD3EAP variants on lung cancer susceptibility among nonsmoking Chinese women.	Gene	2013 Jul 25	Yin J	doi: 10.1016/j.gene.2013.04.017
25917613	NFKB1 common variants and PPP1R13L and CD3EAP in relation to lung cancer risk in a Chinese population.	Gene	2015 Aug 1	Yin J	doi: 10.1016/j.gene.2015.04.059
26563375	Association and interaction of NFKB1 rs28362491 insertion/deletion ATTG polymorphism and PPP1R13L and CD3EAP related to lung cancer risk in a Chinese population.	Tumour Biol	2016 Apr	Yin J	doi: 10.1007/s13277-015-4373-3
19396015	Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines.	Anticancer Drugs	2009 Mar	Nissen KK	doi: 10.1097/CAD.0b013e3283229ae3.
22335888	A specific diplotype defined by PPP1R13L rs1970764, CD3EAP rs967591 and ERCC1 rs11615 and lung cancer risk in a Chinese population.	Lung Cancer	2012 Jun	Yin J	doi: 10.1016/j.lungcan.2012.01.001
28870783	19p13.3-GADD45B common variants and 19q13.3-PPP1R13L and 19q13.3-CD3EAP in lung cancer risk among Chinese.	Chem Biol Interact	2017 Nov 1	Hou W	doi: 10.1016/j.cbi.2017.08.018
29620255	Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment.	Int J Oncol	2018 Jun	Zhang G	doi: 10.3892/ijo.2018.4347
30128886	GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population.	Curr Med Sci	2018 Aug	Yin JY	doi: 10.1007/s11596-018-1938-6

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	45407109	Missense_Mutation	rs756102625	S13F	0.1
BLCA	chr19	45408456	Missense_Mutation	novel	S163L	0.7	RNA_polI_A34
BLCA	chr19	45409243	Silent	novel	K425K	0.09
BLCA	chr19	45408952	Missense_Mutation	novel	K328N	0.29
BLCA	chr19	45409246	Silent	novel	K426K	0.39
BLCA	chr19	45409255	Missense_Mutation	NA	E429D	0.69
BRCA	chr19	45406572	5'UTR	novel		0.44
BRCA	chr19	45408745	Missense_Mutation	novel	K259N	0.12
BRCA	chr19	45409076	Missense_Mutation	NA	E370K	0.16
BRCA	chr19	45408159	Missense_Mutation	novel	S64F	0.16	RNA_polI_A34
CESC	chr19	45408692	Silent	novel	L242L	0.22
CESC	chr19	45408795	Missense_Mutation	novel	T276S	0.25
CESC	chr19	45409012	Missense_Mutation	NA	E348D	0.38
CESC	chr19	45409240	Frame_Shift_Del	novel	*K425Rfs10**	0.27
CESC	chr19	45409242	Frame_Shift_Del	novel	*K426Efs10**	0.27
CESC	chr19	45409802	3'UTR	novel		0.37
CESC	chr19	45409445	Missense_Mutation	rs372336084	E493K	0.45
COAD	chr19	45408984	Missense_Mutation	rs778451525	M339T	0.31
COAD	chr19	45408173	Missense_Mutation	rs778171085	V69I	0.1	RNA_polI_A34
COAD	chr19	45408455	Missense_Mutation	NA	S163T	0.27	RNA_polI_A34
COAD	chr19	45408582	Missense_Mutation	NA	S205L	0.5	RNA_polI_A34
COAD	chr19	45406562	5'UTR	novel		0.44
COAD	chr19	45408999	Missense_Mutation	rs146750944	T344M	0.27
COAD	chr19	45406542	5'UTR	novel		0.29
ESCA	chr19	45408614	Frame_Shift_Del	rs753626854	*N218Ifs4**	0.39	RNA_polI_A34
GBM	chr19	45408916	Frame_Shift_Del	novel	*E316Dfs24**	0.28
GBM	chr19	45408599	Missense_Mutation	rs751999730	R211W	0.16	RNA_polI_A34
HNSC	chr19	45407131	Silent	novel	A20A	0.26
HNSC	chr19	45409055	Missense_Mutation	novel	T363A	0.31
HNSC	chr19	45407134	Silent	novel	K21K	0.24
KIRC	chr19	45409426	Frame_Shift_Ins	novel	*N487Afs32**	0.08
KIRC	chr19	45409428	Missense_Mutation	novel	N487S	0.08
KIRP	chr19	45408268	Frame_Shift_Del	novel	*A101Qfs15**	0.47	RNA_polI_A34
LGG	chr19	45409083	Missense_Mutation	rs112438131	A372V	0.39
LUAD	chr19	45408140	Missense_Mutation	NA	G58R	0.26	RNA_polI_A34
LUAD	chr19	45409246	Missense_Mutation	NA	K426N	0.33
LUAD	chr19	45408721	Missense_Mutation	novel	K251N	0.06	RNA_polI_A34
LUSC	chr19	45408976	Silent	novel	Q336Q	0.17
LUSC	chr19	45408997	Silent	novel	G343G	0.06
LUSC	chr19	45409340	Missense_Mutation	novel	G458R	0.28
LUSC	chr19	45408358	Silent	novel	L130L	0.2
OV	chr19	45408195	Missense_Mutation	novel	K76M	0.11	RNA_polI_A34
OV	chr19	45408507	Missense_Mutation	novel	Q180R	0.26	RNA_polI_A34
OV	chr19	45409445	Missense_Mutation	novel	E493Q	0.26
OV	chr19	45409417	Silent	novel	G483G	0.19
OV	chr19	45408953	Frame_Shift_Del	novel	*R330Kfs8**	0.05
OV	chr19	45407168	Missense_Mutation	NA	E33K	0.46
OV	chr19	45408716	Missense_Mutation	novel	T250S	0.07	RNA_polI_A34
PRAD	chr19	45408709	Silent	rs749731534	P247P	0.38
READ	chr19	45408512	Frame_Shift_Del	NA	*T182Qfs10**	0.17	RNA_polI_A34
READ	chr19	45408142	Silent	novel	G58G	0.16
SARC	chr19	45407186	Missense_Mutation	novel	D39N	0.14
SARC	chr19	45409039	Silent	novel	L357L	0.1
SARC	chr19	45408799	Silent	rs370766397	E277E	0.37
SKCM	chr19	45408920	Silent	NA	L318L	0.14
STAD	chr19	45408614	Frame_Shift_Del	rs753626854	*N218Ifs4**	0.36	RNA_polI_A34
STAD	chr19	45408265	Silent	rs140241488	T99T	0.25
STAD	chr19	45407113	Frame_Shift_Ins	novel	*N17Qfs103**	0.09
STAD	chr19	45408465	Frame_Shift_Del	novel	*N168Tfs14**	0.22	RNA_polI_A34
STAD	chr19	45408940	Frame_Shift_Ins	novel	*T327Yfs81**	0.07
STAD	chr19	45409379	Missense_Mutation	NA	R471W	0.18
STAD	chr19	45409258	Silent	novel	R430R	0.3
STAD	chr19	45408614	Frame_Shift_Del	rs753626854	*N218Ifs4**	0.2	RNA_polI_A34
STAD	chr19	45408885	Missense_Mutation	novel	T306K	0.08
STAD	chr19	45407235	Missense_Mutation	novel	C55F	0.06	RNA_polI_A34
STAD	chr19	45408212	Missense_Mutation	novel	V82F	0.27	RNA_polI_A34
STAD	chr19	45408761	Missense_Mutation	novel	E265Q	0.26
STAD	chr19	45408890	Missense_Mutation	novel	E308Q	0.32
STAD	chr19	45409329	Missense_Mutation	NA	R454M	0.28
STAD	chr19	45408879	Missense_Mutation	NA	G304V	0.14
STAD	chr19	45408614	Frame_Shift_Del	rs753626854	*N218Ifs4**	0.16	RNA_polI_A34
STAD	chr19	45408359	Nonsense_Mutation	NA	Q131*	0.13	RNA_polI_A34
STAD	chr19	45409249	Frame_Shift_Del	novel	*K428Efs5**	0.04
STAD	chr19	45408614	Frame_Shift_Del	rs753626854	*N218Ifs4**	0.13	RNA_polI_A34
UCEC	chr19	45408855	Missense_Mutation	rs143986145	T296M	0.38
UCEC	chr19	45409276	Silent	novel	E436E	0.42
UCEC	chr19	45408393	Missense_Mutation	novel	P142H	0.19	RNA_polI_A34
UCEC	chr19	45409378	Missense_Mutation	novel	S470R	0.49
UCEC	chr19	45408924	Missense_Mutation	NA	E319G	0.16
UCEC	chr19	45408616	Silent	novel	K216K	0.32
UCEC	chr19	45407129	Missense_Mutation	novel	A20T	0.29
UCEC	chr19	45408583	Silent	rs77680493	S205S	0.35
UCEC	chr19	45409452	Missense_Mutation	novel	P495L	0.42
UCEC	chr19	45406665	5'UTR	novel		0.26
UCEC	chr19	45407164	Silent	novel	S31S	0.48
UCEC	chr19	45406529	5'UTR	novel		0.6
UCEC	chr19	45409869	3'UTR	novel		0.37
UCEC	chr19	45408614	Frame_Shift_Del	rs753626854	*N218Ifs4**	0.33	RNA_polI_A34
UCEC	chr19	45408244	Silent	rs200375319	A92A	0.43
UCEC	chr19	45408197	Missense_Mutation	novel	R77W	0.5	RNA_polI_A34
UCEC	chr19	45408143	Missense_Mutation	rs549329477	R59W	0.39	RNA_polI_A34
UCEC	chr19	45409063	Silent	rs755479894	A365A	0.37
UCEC	chr19	45409420	Silent	rs199556175	P484P	0.42
UCEC	chr19	45408614	Frame_Shift_Del	rs753626854	*N218Ifs4**	0.37	RNA_polI_A34
UCEC	chr19	45408616	Silent	novel	K216K	0.37
UCEC	chr19	45409791	3'UTR	novel		0.16
UCEC	chr19	45409460	Missense_Mutation	rs777786624	R498W	0.48
UCEC	chr19	45408396	Missense_Mutation	novel	P143H	0.23	RNA_polI_A34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0712	0.027508
KIRP	DEL	0.0417	0.054726
READ	DEL	0.0667	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1964	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00069	Kaplan-Meier Survival Analysis
SARC	0.00026	Kaplan-Meier Survival Analysis
MESO	0.00016	Kaplan-Meier Survival Analysis
HNSC	0.03	Kaplan-Meier Survival Analysis
SKCM	0.0023	Kaplan-Meier Survival Analysis
KIRP	0.0019	Kaplan-Meier Survival Analysis
UCEC	0.00046	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
LGG	0.00083	Kaplan-Meier Survival Analysis
THCA	0.031	Kaplan-Meier Survival Analysis
LUAD	0.00045	Kaplan-Meier Survival Analysis
UVM	0.012	Kaplan-Meier Survival Analysis

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000117877 (Gene tree)
Gene ID: 10849
Gene Symbol: CD3EAP
Alias: ASE-1|CAST|PAF49
Full Name: CD3e molecule associated protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 4,558 bases
Position: chr19:45,406,209-45,410,766
Accession: 24219
RBP type: canonical RBP
Summary: (CD3e Molecule Associated Protein) is a Protein Coding gene. Among its related pathways are RNA Polymerase I Promoter Escape and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include DNA-directed 5'-3' RNA polymerase activity.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000310966	RNA_polI_A34	PF08208.11	1.6e-37	1	1
ENSP00000465099	RNA_polI_A34	PF08208.11	1.6e-37	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
16809778	RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor.	Mol Cell Biol	2006 Jul	Panov KI	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000590794	CD3EAP-203	489	-	ENSP00000466503	67 (aa)	-	K7EMH2
ENST00000309424	CD3EAP-201	3286	-	ENSP00000310966	510 (aa)	-	O15446
ENST00000592852	CD3EAP-204	1061	-	ENSP00000467771	39 (aa)	-	K7EQC8
ENST00000589804	CD3EAP-202	1830	-	ENSP00000465099	512 (aa)	-	O15446

Gene Model

Click here to download ENSG00000117877's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000117877's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000117877	CD3EAP	95	67.568	ENSAMEG00000012438	CD3EAP	98	61.996	Ailuropoda_melanoleuca
ENSG00000117877	CD3EAP	100	97.436	ENSANAG00000022477	CD3EAP	100	86.019	Aotus_nancymaae
ENSG00000117877	CD3EAP	99	65.537	ENSBTAG00000023601	CD3EAP	98	65.779	Bos_taurus
ENSG00000117877	CD3EAP	100	97.436	ENSCJAG00000012689	CD3EAP	100	83.752	Callithrix_jacchus
ENSG00000117877	CD3EAP	99	57.519	ENSCAFG00000004455	CD3EAP	93	57.707	Canis_familiaris
ENSG00000117877	CD3EAP	99	59.398	ENSCAFG00020011342	CD3EAP	93	59.586	Canis_lupus_dingo
ENSG00000117877	CD3EAP	99	65.537	ENSCHIG00000022038	CD3EAP	97	65.970	Capra_hircus
ENSG00000117877	CD3EAP	99	67.647	ENSTSYG00000036564	CD3EAP	98	66.994	Carlito_syrichta
ENSG00000117877	CD3EAP	97	60.853	ENSCPOG00000033293	CD3EAP	98	60.687	Cavia_porcellus
ENSG00000117877	CD3EAP	100	83.685	ENSCCAG00000024253	CD3EAP	100	83.685	Cebus_capucinus
ENSG00000117877	CD3EAP	99	91.016	ENSCATG00000030677	CD3EAP	99	91.142	Cercocebus_atys
ENSG00000117877	CD3EAP	97	58.189	ENSCLAG00000004691	CD3EAP	87	57.736	Chinchilla_lanigera
ENSG00000117877	CD3EAP	99	90.820	ENSCSAG00000003181	CD3EAP	99	90.945	Chlorocebus_sabaeus
ENSG00000117877	CD3EAP	99	90.039	ENSCANG00000024271	CD3EAP	99	90.157	Colobus_angolensis_palliatus
ENSG00000117877	CD3EAP	85	55.430	ENSCGRG00001023584	Cd3eap	97	52.743	Cricetulus_griseus_chok1gshd
ENSG00000117877	CD3EAP	99	62.949	ENSDNOG00000041816	CD3EAP	98	62.998	Dasypus_novemcinctus
ENSG00000117877	CD3EAP	57	59.871	ENSDORG00000027052	-	87	56.704	Dipodomys_ordii
ENSG00000117877	CD3EAP	98	66.348	ENSEASG00005014188	CD3EAP	97	67.433	Equus_asinus_asinus
ENSG00000117877	CD3EAP	98	66.348	ENSECAG00000032490	CD3EAP	97	67.433	Equus_caballus
ENSG00000117877	CD3EAP	70	58.824	ENSEEUG00000012763	-	86	61.661	Erinaceus_europaeus
ENSG00000117877	CD3EAP	99	58.974	ENSFCAG00000043166	CD3EAP	99	58.974	Felis_catus
ENSG00000117877	CD3EAP	82	57.412	ENSFDAG00000012196	-	86	60.172	Fukomys_damarensis
ENSG00000117877	CD3EAP	100	100.000	ENSGGOG00000015872	-	100	97.070	Gorilla_gorilla
ENSG00000117877	CD3EAP	100	100.000	ENSGGOG00000041192	-	100	97.070	Gorilla_gorilla
ENSG00000117877	CD3EAP	100	60.952	ENSHGLG00000002795	CD3EAP	88	60.952	Heterocephalus_glaber_female
ENSG00000117877	CD3EAP	100	60.952	ENSHGLG00100006839	CD3EAP	88	60.952	Heterocephalus_glaber_male
ENSG00000117877	CD3EAP	97	58.600	ENSSTOG00000002799	CD3EAP	96	57.510	Ictidomys_tridecemlineatus
ENSG00000117877	CD3EAP	83	53.647	ENSJJAG00000013173	Cd3eap	87	55.833	Jaculus_jaculus
ENSG00000117877	CD3EAP	95	59.459	ENSLAFG00000001827	CD3EAP	84	69.359	Loxodonta_africana
ENSG00000117877	CD3EAP	99	90.039	ENSMFAG00000006908	CD3EAP	99	90.157	Macaca_fascicularis
ENSG00000117877	CD3EAP	99	90.039	ENSMNEG00000028086	CD3EAP	99	90.157	Macaca_nemestrina
ENSG00000117877	CD3EAP	99	90.856	ENSMLEG00000043530	CD3EAP	99	90.980	Mandrillus_leucophaeus
ENSG00000117877	CD3EAP	66	60.116	ENSMAUG00000007876	Cd3eap	86	58.960	Mesocricetus_auratus
ENSG00000117877	CD3EAP	99	67.954	ENSMICG00000031258	CD3EAP	98	67.057	Microcebus_murinus
ENSG00000117877	CD3EAP	66	59.347	ENSMOCG00000013766	Cd3eap	82	59.880	Microtus_ochrogaster
ENSG00000117877	CD3EAP	81	33.864	ENSMODG00000021547	-	81	39.286	Monodelphis_domestica
ENSG00000117877	CD3EAP	82	53.882	MGP_CAROLIEiJ_G0029285	Cd3eap	81	57.692	Mus_caroli
ENSG00000117877	CD3EAP	84	54.756	ENSMUSG00000047649	Cd3eap	83	58.382	Mus_musculus
ENSG00000117877	CD3EAP	84	54.608	MGP_SPRETEiJ_G0030369	Cd3eap	97	54.654	Mus_spretus
ENSG00000117877	CD3EAP	99	61.260	ENSMPUG00000005965	CD3EAP	99	61.641	Mustela_putorius_furo
ENSG00000117877	CD3EAP	95	75.676	ENSMLUG00000012319	CD3EAP	97	64.567	Myotis_lucifugus
ENSG00000117877	CD3EAP	77	66.667	ENSNGAG00000015313	Cd3eap	88	61.236	Nannospalax_galili
ENSG00000117877	CD3EAP	100	100.000	ENSNLEG00000035363	CD3EAP	100	94.902	Nomascus_leucogenys
ENSG00000117877	CD3EAP	83	59.719	ENSODEG00000007587	-	99	60.190	Octodon_degus
ENSG00000117877	CD3EAP	97	67.659	ENSOGAG00000013782	CD3EAP	99	66.602	Otolemur_garnettii
ENSG00000117877	CD3EAP	99	65.160	ENSOARG00000009943	CD3EAP	98	65.589	Ovis_aries
ENSG00000117877	CD3EAP	100	100.000	ENSPPAG00000004958	CD3EAP	100	98.828	Pan_paniscus
ENSG00000117877	CD3EAP	99	59.055	ENSPPRG00000001954	CD3EAP	99	59.449	Panthera_pardus
ENSG00000117877	CD3EAP	74	68.966	ENSPTIG00000014078	-	97	58.652	Panthera_tigris_altaica
ENSG00000117877	CD3EAP	100	100.000	ENSPTRG00000011151	CD3EAP	100	99.022	Pan_troglodytes
ENSG00000117877	CD3EAP	99	91.634	ENSPANG00000014599	CD3EAP	99	91.765	Papio_anubis
ENSG00000117877	CD3EAP	97	63.158	ENSPEMG00000018578	Cd3eap	82	63.050	Peromyscus_maniculatus_bairdii
ENSG00000117877	CD3EAP	54	40.214	ENSPCIG00000022939	-	63	48.000	Phascolarctos_cinereus
ENSG00000117877	CD3EAP	100	100.000	ENSPPYG00000010119	CD3EAP	99	95.635	Pongo_abelii
ENSG00000117877	CD3EAP	97	65.789	ENSPCAG00000012953	-	99	66.129	Procavia_capensis
ENSG00000117877	CD3EAP	100	68.511	ENSPCOG00000028780	CD3EAP	98	68.605	Propithecus_coquereli
ENSG00000117877	CD3EAP	99	66.139	ENSPVAG00000001330	CD3EAP	97	67.002	Pteropus_vampyrus
ENSG00000117877	CD3EAP	94	53.608	ENSRNOG00000016825	Cd3eap	100	52.429	Rattus_norvegicus
ENSG00000117877	CD3EAP	99	90.625	ENSRBIG00000040738	CD3EAP	99	90.748	Rhinopithecus_bieti
ENSG00000117877	CD3EAP	99	90.802	ENSRROG00000043410	CD3EAP	99	90.927	Rhinopithecus_roxellana
ENSG00000117877	CD3EAP	100	80.851	ENSSBOG00000032782	CD3EAP	100	81.044	Saimiri_boliviensis_boliviensis
ENSG00000117877	CD3EAP	68	53.258	ENSSARG00000008700	-	90	56.678	Sorex_araneus
ENSG00000117877	CD3EAP	95	70.270	ENSSSCG00000020754	CD3EAP	98	63.105	Sus_scrofa
ENSG00000117877	CD3EAP	99	64.368	ENSTTRG00000008311	CD3EAP	97	65.815	Tursiops_truncatus
ENSG00000117877	CD3EAP	99	62.311	ENSUAMG00000020204	CD3EAP	98	62.380	Ursus_americanus
ENSG00000117877	CD3EAP	99	62.311	ENSUMAG00000023587	CD3EAP	98	62.188	Ursus_maritimus
ENSG00000117877	CD3EAP	99	57.491	ENSVVUG00000004115	CD3EAP	93	58.083	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000120	RNA polymerase I transcription factor complex	9426281.	TAS	Component
GO:0001650	fibrillar center	-	IDA	Component
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	-	IEA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005694	chromosome	-	IEA	Component
GO:0005730	nucleolus	9426281.	TAS	Component
GO:0005739	mitochondrion	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006361	transcription initiation from RNA polymerase I promoter	-	TAS	Process
GO:0006362	transcription elongation from RNA polymerase I promoter	-	TAS	Process
GO:0006363	termination of RNA polymerase I transcription	-	TAS	Process
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	10373416.	TAS	Process
GO:0009303	rRNA transcription	9426281.	TAS	Process
GO:0045815	positive regulation of gene expression, epigenetic	-	TAS	Process

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Note: to get the extension of tumor abbreviations.