EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr9	4844670	Missense_Mutation	novel	E286K	0.17
BLCA	chr9	4793019	5'UTR	novel		0.3
BRCA	chr9	4826926	Missense_Mutation	novel	R93C	0.1	RTC
BRCA	chr9	4850331	Intron	rs533430622		0.2
BRCA	chr9	4841274	Silent	NA	V209V	0.69
CESC	chr9	4793082	5'UTR	novel		0.39
CHOL	chr9	4841229	Splice_Region	novel		0.31
COAD	chr9	4826997	Silent	NA	V116V	0.29
COAD	chr9	4849456	Missense_Mutation	rs781574564	V293I	0.29
COAD	chr9	4841261	Missense_Mutation	rs745330205	A205V	0.22
COAD	chr9	4860138	Missense_Mutation	rs142051884	R329W	0.44
COAD	chr9	4860423	3'UTR	novel		0.28
COAD	chr9	4827002	Missense_Mutation	novel	R118L	0.29
COAD	chr9	4860210	Missense_Mutation	NA	G353W	0.24
ESCA	chr9	4792968	5'UTR	novel		0.35
ESCA	chr9	4793197	Missense_Mutation	novel	R36W	0.4	RTC
GBM	chr9	4834265	Missense_Mutation	novel	A195V	0.06
GBM	chr9	4849551	Splice_Site	novel	X324_splice	0.5
GBM	chr9	4860322	3'UTR	novel		0.35
GBM	chr9	4826973	Silent	novel	F108F	0.05
HNSC	chr9	4826916	Silent	novel	C89C	0.09
HNSC	chr9	4844556	Missense_Mutation	novel	E248K	0.22
LUAD	chr9	4833225	Silent	NA	L152L	0.19
LUAD	chr9	4844632	Missense_Mutation	NA	E273A	0.24
LUAD	chr9	4844522	Splice_Region	novel		0.3
LUSC	chr9	4823599	Missense_Mutation	rs115216700	R63Q	0.58	RTC
LUSC	chr9	4841242	Missense_Mutation	novel	R199S	0.2
LUSC	chr9	4844532	Missense_Mutation	NA	G240C	0.79
OV	chr9	4860180	Missense_Mutation	novel	T343S	0.05
OV	chr9	4833200	Missense_Mutation	novel	G144V	0.04
PRAD	chr9	4834198	Missense_Mutation	NA	V173M	0.52
READ	chr9	4823599	Missense_Mutation	rs115216700	R63Q	0.22	RTC
READ	chr9	4849482	Silent	rs767438290	A301A	0.27
READ	chr9	4844526	Missense_Mutation	NA	S238P	0.36
SARC	chr9	4849484	Missense_Mutation	novel	L302P	0.21
SARC	chr9	4860199	Missense_Mutation	novel	E349V	0.3
SKCM	chr9	4849544	Missense_Mutation	novel	P322L	0.36
SKCM	chr9	4860309	3'UTR	novel		0.27
SKCM	chr9	4793151	Silent	novel	L20L	0.38
SKCM	chr9	4849543	Missense_Mutation	novel	P322S	0.4
SKCM	chr9	4826983	Missense_Mutation	NA	P112S	0.48
SKCM	chr9	4850297	Intron	novel		0.82
SKCM	chr9	4826886	Silent	NA	L79L	0.05
SKCM	chr9	4841214	Intron	novel		0.26
SKCM	chr9	4844531	Silent	rs749284895	P239P	0.22
SKCM	chr9	4844532	Missense_Mutation	novel	G240S	0.22
SKCM	chr9	4834165	Missense_Mutation	rs148074533	G162R	0.17
SKCM	chr9	4823558	Silent	rs747429340	A49A	0.29
SKCM	chr9	4826969	Missense_Mutation	NA	P107L	0.17
STAD	chr9	4793106	Silent	NA	A5A	0.48
STAD	chr9	4841245	Missense_Mutation	rs371417592	V200M	0.35
STAD	chr9	4849482	Silent	rs767438290	A301A	0.25
STAD	chr9	4844593	Missense_Mutation	NA	A260V	0.24
UCEC	chr9	4793123	Missense_Mutation	novel	A11G	0.33	RTC
UCEC	chr9	4833153	Splice_Site	novel	X129_splice	0.31
UCEC	chr9	4826985	Silent	rs377073783	P112P	0.34
UCEC	chr9	4850328	Intron	NA		0.13
UCEC	chr9	4841235	Nonsense_Mutation	novel	Y196*	0.17
UCEC	chr9	4826920	Missense_Mutation	rs150920079	V91I	0.45	RTC
UCEC	chr9	4841288	Missense_Mutation	novel	S214I	0.19
UCEC	chr9	4850366	Intron	novel		0.09
UCEC	chr9	4860151	Missense_Mutation	novel	S333N	0.37
UCEC	chr9	4834150	Missense_Mutation	rs116589736	R157W	0.32
UCEC	chr9	4823588	Silent	rs768617640	T59T	0.36
UCEC	chr9	4826988	Frame_Shift_Del	novel	I115*	0.45
UCEC	chr9	4841288	Missense_Mutation	novel	S214N	0.08
UCEC	chr9	4833175	Missense_Mutation	novel	A136T	0.48
UCEC	chr9	4860329	3'UTR	rs191788496		0.5
UCEC	chr9	4826938	Missense_Mutation	novel	Y97H	0.06	RTC
UCEC	chr9	4826993	Missense_Mutation	NA	I115T	0.13
UCEC	chr9	4823599	Missense_Mutation	rs115216700	R63Q	0.43	RTC
UCEC	chr9	4834227	Silent	rs374022520	L182L	0.44
UCEC	chr9	4834209	Silent	rs532877046	V176V	0.27
UCEC	chr9	4792971	5'UTR	novel		0.48
UCEC	chr9	4834177	Missense_Mutation	novel	E166K	0.53
UCEC	chr9	4849482	Silent	rs767438290	A301A	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.1544	0.073854
LAML	DEL	0.0105	0.24147
OV	DEL	0.4318	0.00059831
STAD	AMP	0.1088	0.0062179
TGCT	DEL	0.3867	7.3329e-05
THCA	DEL	0.0301	0.24038
THYM	DEL	0.0325	0.022012

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0068	Kaplan-Meier Survival Analysis
KIRC	0.00036	Kaplan-Meier Survival Analysis
SARC	0.015	Kaplan-Meier Survival Analysis
UCS	0.006	Kaplan-Meier Survival Analysis
BRCA	0.018	Kaplan-Meier Survival Analysis
KIRP	0.048	Kaplan-Meier Survival Analysis
PAAD	0.048	Kaplan-Meier Survival Analysis
BLCA	0.043	Kaplan-Meier Survival Analysis
CESC	0.023	Kaplan-Meier Survival Analysis
UCEC	0.048	Kaplan-Meier Survival Analysis
GBM	0.0063	Kaplan-Meier Survival Analysis
LIHC	0.00089	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000120158 (Gene tree)
Gene ID: 10171
Gene Symbol: RCL1
Alias: RPCL1|RNAC
Full Name: RNA terminal phosphate cyclase like 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 93,084 bases
Position: chr9:4,792,834-4,885,917
Accession: 17687
RBP type: canonical RBP
Summary: (RNA Terminal Phosphate Cyclase Like 1) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and RNA-3'-phosphate cyclase activity. An important paralog of this gene is RTCA.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000371169	RTC	PF01137.21	1.4e-60	1	1
ENSP00000371151	RTC	PF01137.21	2.2e-33	1	1
ENSP00000412000	RTC	PF01137.21	7.6e-12	1	1
ENSP00000371147	RTC	PF01137.21	7.2e-07	1	1
ENSP00000371149	RTC	PF01137.21	7.2e-07	1	1
ENSP00000388096	RTC	PF01137.21	7.2e-07	1	1
ENSP00000412000	RTC_insert	PF05189.13	8e-37	1	1
ENSP00000371169	RTC_insert	PF05189.13	2.4e-36	1	1
ENSP00000413381	RTC_insert	PF05189.13	1.6e-29	1	1
ENSP00000371147	RTC_insert	PF05189.13	3.7e-29	1	1
ENSP00000371149	RTC_insert	PF05189.13	3.7e-29	1	1
ENSP00000388096	RTC_insert	PF05189.13	3.7e-29	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
19332556	A novel small-subunit processome assembly intermediate that contains the U3 snoRNP, nucleolin, RRP5, and DBP4.	Mol Cell Biol	2009 Jun	Turner AJ	doi: 10.1128/MCB.00029-09
21367972	Crystal structure of Rcl1, an essential component of the eukaryal pre-rRNA processosome implicated in 18s rRNA biogenesis.	RNA	2011 Apr	Tanaka N	doi: 10.1261/rna.2571811
16376378	GTP-dependent formation of a ribonucleoprotein subcomplex required for ribosome biogenesis.	J Mol Biol	2006 Feb 17	Karbstein K	-
31217256	Rrp5 Establishes a Checkpoint for 60S Assembly During 40S Maturation.	RNA	2019 Jun 19	Khoshnevis S	doi: 10.1261/rna.071225.119
16307926	An essential GTPase promotes assembly of preribosomal RNA processing complexes.	Mol Cell	2005 Nov 23	Karbstein K	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000441844	RCL1-205	497	-	ENSP00000413381	137 (aa)	-	Q5VZU2
ENST00000381750	RCL1-204	2134	XM_006716715	ENSP00000371169	373 (aa)	XP_006716778	Q9Y2P8
ENST00000442869	RCL1-206	1644	-	ENSP00000412000	215 (aa)	-	Q5VZU3
ENST00000381728	RCL1-201	758	XM_017014176	ENSP00000371147	187 (aa)	XP_016869665	Q9Y2P8
ENST00000473230	RCL1-209	441	-	-	- (aa)	-	-
ENST00000381732	RCL1-203	804	-	ENSP00000371151	175 (aa)	-	Q5VYW8
ENST00000381730	RCL1-202	801	-	ENSP00000371149	187 (aa)	-	Q9Y2P8
ENST00000448872	RCL1-208	1459	XM_011517673	ENSP00000388096	187 (aa)	XP_011515975	Q9Y2P8
ENST00000445485	RCL1-207	1878	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000120158's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000120158	Hemoglobin A, Glycosylated	6.945E-06	19875614
ENSG00000120158	Heart Failure	9.1760822E-004	-
ENSG00000120158	Platelet Function Tests	1.7895200E-005	-
ENSG00000120158	Platelet Function Tests	7.9723527E-006	-
ENSG00000120158	Erythrocyte Count	1E-8	28017375
ENSG00000120158	Platelet Count	1E-29	22139419
ENSG00000120158	Erythrocyte Count	1E-19	23222517
ENSG00000120158	Erythrocyte Count	2E-7	23263863
ENSG00000120158	Erythrocyte Indices	1E-8	28017375
ENSG00000120158	Erythrocyte Indices	2E-9	28017375
ENSG00000120158	Erythrocyte Count	3E-14	20139978
ENSG00000120158	Platelet Count	1E-9	24026423
ENSG00000120158	Erythrocyte Indices	6E-11	20139978
ENSG00000120158	Hemoglobins	6E-11	20139978
ENSG00000120158	Erythrocyte Count	1E-11	28017375
ENSG00000120158	Platelet Count	1E-6	23263863
ENSG00000120158	Erythrocyte Count	3E-20	19862010
ENSG00000120158	Erythrocyte Indices	2E-14	19862010
ENSG00000120158	Erythrocyte Count	5E-23	28017375
ENSG00000120158	Erythrocyte Indices	5E-6	23263863

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000120158	rs7853365	9	4855858	C	High light scatter reticulocyte percentage of red cells	27863252	[0.028-0.046] unit decrease	0.03710078	EFO_0007986
ENSG00000120158	rs17803780	9	4849647	C	Mean corpuscular hemoglobin	27863252	[0.081-0.098] unit decrease	0.08967346	EFO_0004527
ENSG00000120158	rs7874244	9	4847570	C	Red blood cell count	27863252	[0.053-0.07] unit increase	0.0619076	EFO_0004305
ENSG00000120158	rs17803780	9	4849647	C	Mean corpuscular volume	27863252	[0.088-0.105] unit decrease	0.09619212	EFO_0004526
ENSG00000120158	rs2236496	9	4844265	C	Mean corpuscular hemoglobin	20139978	[0.053-0.101] unit decrease	0.077	EFO_0004509\|EFO_0004527
ENSG00000120158	rs2236496	9	4844265	C	Mean corpuscular volume	20139978	[0.066-0.114] unit decrease	0.09	EFO_0004526
ENSG00000120158	rs10758658	9	4856877	?	Red blood cell count	28017375			EFO_0004305
ENSG00000120158	rs10758658	9	4856877	A	Mean corpuscular volume	28017375	[0.0028-0.0052] unit decrease	0.004	EFO_0004526
ENSG00000120158	rs10758658	9	4856877	?	Mean corpuscular volume	28017375			EFO_0004526
ENSG00000120158	rs10758656	9	4852599	A	Mean corpuscular hemoglobin	28017375	[0.0026-0.0054] unit increase	0.004	EFO_0004527
ENSG00000120158	rs10758658	9	4856877	?	Mean corpuscular hemoglobin	28017375			EFO_0004527
ENSG00000120158	rs2236496	9	4844265	C	Red blood cell traits	23222517	[0.22-0.34] unit decrease	0.279	EFO_0004526
ENSG00000120158	rs457287	9	4834394	A	Platelet count	23263863	[3.55-8.42] unit decrease	5.987	EFO_0004309
ENSG00000120158	rs2236496	9	4844265	T	Mean corpuscular volume	23263863	[0.26-0.57] unit increase	0.4162	EFO_0004526
ENSG00000120158	rs10815094	9	4845520	A	Mean corpuscular hemoglobin	23263863	[0.083-0.209] unit increase	0.1461	EFO_0004527
ENSG00000120158	rs13300663	9	4814948	C	Platelet count	22139419	[4.64-6.53] 10^9/l increase	5.585	EFO_0004309
ENSG00000120158	rs10758658	9	4856877	A	Mean corpuscular volume	19862010	[0.003-0.005] fl decrease	0	EFO_0004526
ENSG00000120158	rs10758658	9	4856877	A	Mean corpuscular hemoglobin	19862010	[0.004-0.006] pg decrease	0	EFO_0004527
ENSG00000120158	rs10758658	9	4856877	?	Red blood cell count	29403010	[0.028-0.045] unit increase novel	0.03646	EFO_0004305
ENSG00000120158	rs10758656	9	4852599	?	Mean corpuscular volume	29403010	[0.07-0.087] unit decrease novel	0.07883	EFO_0004526
ENSG00000120158	rs3824430	9	4847168	?	Mean corpuscular hemoglobin	29403010	[0.062-0.079] unit decrease novel	0.07049	EFO_0004527
ENSG00000120158	rs12351570	9	4806633	?	Platelet count	29403010	[0.069-0.099] unit decrease novel	0.08416	EFO_0004309
ENSG00000120158	rs10758656	9	4852599	G	Immature fraction of reticulocytes	27863252	[0.056-0.073] unit decrease	0.06415109	EFO_0007986
ENSG00000120158	rs10974808	9	4840380	G	Platelet count	27863252	[0.11-0.13] unit increase	0.1217556	EFO_0004309
ENSG00000120158	rs1887430	9	4856234	A	Platelet count	27863252	[0.063-0.078] unit increase	0.07034669	EFO_0004309
ENSG00000120158	rs10815095	9	4848297	G	Red cell distribution width	27863252	[0.032-0.049] unit increase	0.04005609	EFO_0005192
ENSG00000120158	rs7853365	9	4855858	C	High light scatter reticulocyte count	27863252	[0.019-0.036] unit decrease	0.02752521	EFO_0007986
ENSG00000120158	rs10974808	9	4840380	G	Plateletcrit	27863252	[0.13-0.15] unit increase	0.1356046	EFO_0007985
ENSG00000120158	rs1887430	9	4856234	A	Plateletcrit	27863252	[0.071-0.086] unit increase	0.07844472	EFO_0007985
ENSG00000120158	rs296847	9	4793798	T	Eosinophil counts	27863252	[0.015-0.03] unit increase	0.02221495	EFO_0004842
ENSG00000120158	rs10739069	9	4863305	A	Red cell distribution width	28957414	[0.031-0.05] unit increase	0.0407602	EFO_0005192
ENSG00000120158	rs10758656	9	4852599	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000120158	rs10758656	9	4852599	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000120158	rs10758656	9	4852599	?	Red blood cell count	30595370			EFO_0004305
ENSG00000120158	rs460182	9	4850613	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000120158's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000120158	RCL1	96	87.023	ENSAPOG00000015666	rcl1	100	78.877	Acanthochromis_polyacanthus
ENSG00000120158	RCL1	100	97.674	ENSAMEG00000002631	RCL1	100	97.587	Ailuropoda_melanoleuca
ENSG00000120158	RCL1	96	87.786	ENSACIG00000021195	rcl1	99	79.459	Amphilophus_citrinellus
ENSG00000120158	RCL1	96	85.496	ENSAOCG00000002223	rcl1	100	78.342	Amphiprion_ocellaris
ENSG00000120158	RCL1	96	85.496	ENSAPEG00000006905	rcl1	100	78.610	Amphiprion_percula
ENSG00000120158	RCL1	100	78.704	ENSATEG00000020026	rcl1	99	76.757	Anabas_testudineus
ENSG00000120158	RCL1	100	86.047	ENSAPLG00000006031	RCL1	100	87.195	Anas_platyrhynchos
ENSG00000120158	RCL1	100	85.581	ENSACAG00000003640	RCL1	100	85.255	Anolis_carolinensis
ENSG00000120158	RCL1	100	99.535	ENSANAG00000037372	RCL1	100	98.928	Aotus_nancymaae
ENSG00000120158	RCL1	100	82.870	ENSACLG00000021724	rcl1	99	78.919	Astatotilapia_calliptera
ENSG00000120158	RCL1	96	84.733	ENSAMXG00000033394	rcl1	99	78.533	Astyanax_mexicanus
ENSG00000120158	RCL1	99	47.340	WBGene00022852	ZK1127.5	99	47.340	Caenorhabditis_elegans
ENSG00000120158	RCL1	100	99.732	ENSCJAG00000011202	RCL1	100	99.732	Callithrix_jacchus
ENSG00000120158	RCL1	100	97.209	ENSCAFG00000002091	RCL1	100	96.515	Canis_familiaris
ENSG00000120158	RCL1	100	97.209	ENSCAFG00020000638	RCL1	78	96.515	Canis_lupus_dingo
ENSG00000120158	RCL1	100	96.515	ENSCHIG00000012407	RCL1	100	96.515	Capra_hircus
ENSG00000120158	RCL1	100	99.070	ENSTSYG00000009592	RCL1	100	97.326	Carlito_syrichta
ENSG00000120158	RCL1	68	80.925	ENSCAPG00000013575	RCL1	100	80.925	Cavia_aperea
ENSG00000120158	RCL1	100	97.674	ENSCPOG00000015354	RCL1	100	97.319	Cavia_porcellus
ENSG00000120158	RCL1	100	99.732	ENSCCAG00000033505	RCL1	100	99.732	Cebus_capucinus
ENSG00000120158	RCL1	100	99.465	ENSCATG00000034721	RCL1	100	99.465	Cercocebus_atys
ENSG00000120158	RCL1	100	97.587	ENSCLAG00000007445	RCL1	100	97.587	Chinchilla_lanigera
ENSG00000120158	RCL1	100	99.535	ENSCSAG00000008811	RCL1	100	99.464	Chlorocebus_sabaeus
ENSG00000120158	RCL1	96	95.420	ENSCHOG00000007216	RCL1	100	82.043	Choloepus_hoffmanni
ENSG00000120158	RCL1	100	89.302	ENSCPBG00000025481	RCL1	94	89.362	Chrysemys_picta_bellii
ENSG00000120158	RCL1	99	58.525	ENSCING00000019565	-	98	58.919	Ciona_intestinalis
ENSG00000120158	RCL1	96	30.374	ENSCING00000007875	-	55	30.374	Ciona_intestinalis
ENSG00000120158	RCL1	96	30.806	ENSCSAVG00000007269	-	55	30.806	Ciona_savignyi
ENSG00000120158	RCL1	100	100.000	ENSCANG00000027099	RCL1	100	99.732	Colobus_angolensis_palliatus
ENSG00000120158	RCL1	100	96.247	ENSCGRG00001013748	Rcl1	100	96.247	Cricetulus_griseus_chok1gshd
ENSG00000120158	RCL1	97	95.673	ENSCGRG00000005843	Rcl1	99	96.037	Cricetulus_griseus_crigri
ENSG00000120158	RCL1	100	81.944	ENSCSEG00000000712	rcl1	97	79.459	Cynoglossus_semilaevis
ENSG00000120158	RCL1	100	82.407	ENSCVAG00000011536	rcl1	99	80.541	Cyprinodon_variegatus
ENSG00000120158	RCL1	96	86.260	ENSDARG00000038312	rcl1	100	76.567	Danio_rerio
ENSG00000120158	RCL1	100	96.744	ENSDNOG00000019911	RCL1	100	96.981	Dasypus_novemcinctus
ENSG00000120158	RCL1	100	97.209	ENSDORG00000015645	Rcl1	100	96.783	Dipodomys_ordii
ENSG00000120158	RCL1	99	53.968	FBgn0020909	Rtc1	98	53.968	Drosophila_melanogaster
ENSG00000120158	RCL1	72	100.000	ENSETEG00000014087	-	82	100.000	Echinops_telfairi
ENSG00000120158	RCL1	100	53.600	ENSEBUG00000016621	-	100	53.600	Eptatretus_burgeri
ENSG00000120158	RCL1	100	97.855	ENSEASG00005010653	RCL1	100	97.855	Equus_asinus_asinus
ENSG00000120158	RCL1	100	97.855	ENSECAG00000015973	RCL1	100	97.855	Equus_caballus
ENSG00000120158	RCL1	96	95.420	ENSEEUG00000009801	RCL1	100	82.038	Erinaceus_europaeus
ENSG00000120158	RCL1	100	77.778	ENSELUG00000007353	rcl1	100	75.936	Esox_lucius
ENSG00000120158	RCL1	100	95.710	ENSFCAG00000014557	RCL1	100	95.710	Felis_catus
ENSG00000120158	RCL1	100	85.581	ENSFALG00000010553	RCL1	94	82.817	Ficedula_albicollis
ENSG00000120158	RCL1	100	96.744	ENSFDAG00000004209	RCL1	100	96.636	Fukomys_damarensis
ENSG00000120158	RCL1	100	82.407	ENSFHEG00000011228	rcl1	99	80.000	Fundulus_heteroclitus
ENSG00000120158	RCL1	96	84.733	ENSGMOG00000004677	rcl1	99	77.838	Gadus_morhua
ENSG00000120158	RCL1	99	86.179	ENSGALG00000015024	RCL1	99	86.179	Gallus_gallus
ENSG00000120158	RCL1	100	80.556	ENSGAFG00000007257	rcl1	99	78.378	Gambusia_affinis
ENSG00000120158	RCL1	100	80.093	ENSGACG00000017474	rcl1	100	77.540	Gasterosteus_aculeatus
ENSG00000120158	RCL1	100	90.233	ENSGAGG00000003689	RCL1	100	89.812	Gopherus_agassizii
ENSG00000120158	RCL1	100	99.535	ENSGGOG00000015041	RCL1	100	99.465	Gorilla_gorilla
ENSG00000120158	RCL1	100	83.333	ENSHBUG00000001393	rcl1	99	79.189	Haplochromis_burtoni
ENSG00000120158	RCL1	97	87.293	ENSHGLG00000005368	-	100	80.965	Heterocephalus_glaber_female
ENSG00000120158	RCL1	100	97.674	ENSHGLG00000016452	RCL1	100	97.587	Heterocephalus_glaber_female
ENSG00000120158	RCL1	98	86.567	ENSHGLG00100018010	-	100	82.038	Heterocephalus_glaber_male
ENSG00000120158	RCL1	100	97.674	ENSHGLG00100008718	-	100	90.617	Heterocephalus_glaber_male
ENSG00000120158	RCL1	100	81.019	ENSHCOG00000020170	rcl1	99	78.378	Hippocampus_comes
ENSG00000120158	RCL1	100	81.019	ENSIPUG00000018054	RCL1	99	79.891	Ictalurus_punctatus
ENSG00000120158	RCL1	100	97.587	ENSSTOG00000000023	RCL1	100	97.587	Ictidomys_tridecemlineatus
ENSG00000120158	RCL1	93	72.637	ENSJJAG00000000764	-	98	72.637	Jaculus_jaculus
ENSG00000120158	RCL1	100	96.279	ENSJJAG00000022803	-	100	95.710	Jaculus_jaculus
ENSG00000120158	RCL1	100	84.718	ENSJJAG00000015632	-	100	84.718	Jaculus_jaculus
ENSG00000120158	RCL1	100	79.630	ENSKMAG00000011946	rcl1	99	78.202	Kryptolebias_marmoratus
ENSG00000120158	RCL1	100	83.333	ENSLBEG00000003957	rcl1	99	76.216	Labrus_bergylta
ENSG00000120158	RCL1	96	85.496	ENSLACG00000004594	RCL1	98	85.489	Latimeria_chalumnae
ENSG00000120158	RCL1	100	84.651	ENSLOCG00000010148	rcl1	98	81.769	Lepisosteus_oculatus
ENSG00000120158	RCL1	100	93.834	ENSLAFG00000017495	RCL1	100	93.834	Loxodonta_africana
ENSG00000120158	RCL1	100	99.535	ENSMFAG00000037906	RCL1	100	99.464	Macaca_fascicularis
ENSG00000120158	RCL1	100	93.714	ENSMMUG00000041751	-	100	93.714	Macaca_mulatta
ENSG00000120158	RCL1	100	99.535	ENSMNEG00000012288	RCL1	100	99.465	Macaca_nemestrina
ENSG00000120158	RCL1	100	99.535	ENSMLEG00000043088	RCL1	100	99.464	Mandrillus_leucophaeus
ENSG00000120158	RCL1	72	30.247	ENSMLEG00000042151	RTCA	51	30.247	Mandrillus_leucophaeus
ENSG00000120158	RCL1	96	85.496	ENSMAMG00000008311	rcl1	99	79.189	Mastacembelus_armatus
ENSG00000120158	RCL1	100	82.870	ENSMZEG00005017292	rcl1	99	78.919	Maylandia_zebra
ENSG00000120158	RCL1	100	84.018	ENSMGAG00000002245	RCL1	100	84.018	Meleagris_gallopavo
ENSG00000120158	RCL1	100	96.279	ENSMAUG00000008922	Rcl1	100	96.279	Mesocricetus_auratus
ENSG00000120158	RCL1	100	97.209	ENSMICG00000015562	RCL1	100	97.051	Microcebus_murinus
ENSG00000120158	RCL1	100	97.319	ENSMOCG00000012145	Rcl1	100	97.319	Microtus_ochrogaster
ENSG00000120158	RCL1	96	81.679	ENSMMOG00000021264	rcl1	99	76.011	Mola_mola
ENSG00000120158	RCL1	96	93.130	ENSMODG00000015377	RCL1	94	93.803	Monodelphis_domestica
ENSG00000120158	RCL1	100	80.093	ENSMALG00000018618	rcl1	99	77.838	Monopterus_albus
ENSG00000120158	RCL1	100	97.051	MGP_CAROLIEiJ_G0022853	Rcl1	100	97.051	Mus_caroli
ENSG00000120158	RCL1	100	97.051	ENSMUSG00000024785	Rcl1	100	97.051	Mus_musculus
ENSG00000120158	RCL1	100	96.744	MGP_PahariEiJ_G0014346	Rcl1	100	97.059	Mus_pahari
ENSG00000120158	RCL1	100	96.247	MGP_SPRETEiJ_G0023771	Rcl1	100	96.471	Mus_spretus
ENSG00000120158	RCL1	100	96.515	ENSMPUG00000004998	RCL1	100	96.515	Mustela_putorius_furo
ENSG00000120158	RCL1	100	97.051	ENSMLUG00000009654	RCL1	100	97.051	Myotis_lucifugus
ENSG00000120158	RCL1	100	97.674	ENSNGAG00000015327	Rcl1	100	97.587	Nannospalax_galili
ENSG00000120158	RCL1	97	30.415	ENSNGAG00000011540	Rtca	59	30.415	Nannospalax_galili
ENSG00000120158	RCL1	100	82.870	ENSNBRG00000019854	rcl1	96	74.581	Neolamprologus_brichardi
ENSG00000120158	RCL1	100	96.783	ENSNLEG00000008891	RCL1	100	96.783	Nomascus_leucogenys
ENSG00000120158	RCL1	97	94.231	ENSMEUG00000007653	RCL1	100	87.131	Notamacropus_eugenii
ENSG00000120158	RCL1	100	96.783	ENSOPRG00000010965	RCL1	100	96.783	Ochotona_princeps
ENSG00000120158	RCL1	98	96.739	ENSODEG00000004151	RCL1	96	81.098	Octodon_degus
ENSG00000120158	RCL1	100	82.870	ENSONIG00000003871	rcl1	99	78.919	Oreochromis_niloticus
ENSG00000120158	RCL1	97	88.152	ENSOANG00000013193	-	100	87.747	Ornithorhynchus_anatinus
ENSG00000120158	RCL1	75	83.333	ENSOANG00000013194	-	100	83.333	Ornithorhynchus_anatinus
ENSG00000120158	RCL1	100	98.605	ENSOCUG00000008161	RCL1	100	98.391	Oryctolagus_cuniculus
ENSG00000120158	RCL1	96	83.206	ENSORLG00000010443	rcl1	100	76.471	Oryzias_latipes
ENSG00000120158	RCL1	96	83.206	ENSORLG00020012211	rcl1	100	76.471	Oryzias_latipes_hni
ENSG00000120158	RCL1	100	78.704	ENSORLG00015001122	rcl1	100	76.203	Oryzias_latipes_hsok
ENSG00000120158	RCL1	100	81.019	ENSOMEG00000022976	rcl1	88	78.075	Oryzias_melastigma
ENSG00000120158	RCL1	100	96.279	ENSOGAG00000007480	RCL1	100	95.979	Otolemur_garnettii
ENSG00000120158	RCL1	100	96.783	ENSOARG00000013463	RCL1	100	96.783	Ovis_aries
ENSG00000120158	RCL1	96	30.189	ENSPPAG00000035119	RTCA	65	30.189	Pan_paniscus
ENSG00000120158	RCL1	100	100.000	ENSPPAG00000037958	RCL1	100	99.732	Pan_paniscus
ENSG00000120158	RCL1	100	94.906	ENSPPRG00000022645	RCL1	100	94.906	Panthera_pardus
ENSG00000120158	RCL1	100	94.884	ENSPTIG00000019031	RCL1	100	94.884	Panthera_tigris_altaica
ENSG00000120158	RCL1	100	100.000	ENSPTRG00000020743	RCL1	100	100.000	Pan_troglodytes
ENSG00000120158	RCL1	100	99.535	ENSPANG00000025151	RCL1	100	99.464	Papio_anubis
ENSG00000120158	RCL1	96	87.786	ENSPKIG00000021022	rcl1	100	78.075	Paramormyrops_kingsleyae
ENSG00000120158	RCL1	100	89.302	ENSPSIG00000012302	RCL1	100	89.634	Pelodiscus_sinensis
ENSG00000120158	RCL1	100	79.630	ENSPMGG00000024007	rcl1	100	76.738	Periophthalmus_magnuspinnatus
ENSG00000120158	RCL1	100	97.319	ENSPEMG00000023275	Rcl1	100	97.319	Peromyscus_maniculatus_bairdii
ENSG00000120158	RCL1	97	30.959	ENSPMAG00000009110	rtca	96	30.959	Petromyzon_marinus
ENSG00000120158	RCL1	93	72.656	ENSPMAG00000005419	-	95	69.663	Petromyzon_marinus
ENSG00000120158	RCL1	100	94.102	ENSPCIG00000000188	RCL1	100	94.102	Phascolarctos_cinereus
ENSG00000120158	RCL1	100	81.481	ENSPFOG00000019682	rcl1	99	79.189	Poecilia_formosa
ENSG00000120158	RCL1	100	81.481	ENSPLAG00000022354	rcl1	99	79.189	Poecilia_latipinna
ENSG00000120158	RCL1	100	81.481	ENSPMEG00000008131	rcl1	99	79.189	Poecilia_mexicana
ENSG00000120158	RCL1	100	81.019	ENSPREG00000008032	rcl1	99	78.919	Poecilia_reticulata
ENSG00000120158	RCL1	100	99.732	ENSPPYG00000019244	RCL1	100	99.732	Pongo_abelii
ENSG00000120158	RCL1	100	86.059	ENSPCAG00000001440	RCL1	100	86.059	Procavia_capensis
ENSG00000120158	RCL1	100	99.070	ENSPCOG00000009611	RCL1	100	98.396	Propithecus_coquereli
ENSG00000120158	RCL1	100	97.319	ENSPVAG00000015752	RCL1	100	97.319	Pteropus_vampyrus
ENSG00000120158	RCL1	100	82.870	ENSPNYG00000012910	rcl1	99	78.919	Pundamilia_nyererei
ENSG00000120158	RCL1	96	86.260	ENSPNAG00000028307	rcl1	92	78.552	Pygocentrus_nattereri
ENSG00000120158	RCL1	100	96.783	ENSRNOG00000015491	Rcl1	100	96.783	Rattus_norvegicus
ENSG00000120158	RCL1	100	99.535	ENSRBIG00000035818	RCL1	100	99.464	Rhinopithecus_bieti
ENSG00000120158	RCL1	100	99.535	ENSRROG00000029781	RCL1	100	99.465	Rhinopithecus_roxellana
ENSG00000120158	RCL1	98	36.486	YOL010W	-	97	35.310	Saccharomyces_cerevisiae
ENSG00000120158	RCL1	100	99.196	ENSSBOG00000026369	RCL1	100	99.196	Saimiri_boliviensis_boliviensis
ENSG00000120158	RCL1	96	93.333	ENSSHAG00000014086	RCL1	100	92.727	Sarcophilus_harrisii
ENSG00000120158	RCL1	96	87.023	ENSSFOG00015023020	rcl1	100	78.342	Scleropages_formosus
ENSG00000120158	RCL1	100	80.556	ENSSMAG00000019751	rcl1	85	79.189	Scophthalmus_maximus
ENSG00000120158	RCL1	100	80.556	ENSSDUG00000006349	rcl1	100	78.075	Seriola_dumerili
ENSG00000120158	RCL1	100	81.481	ENSSLDG00000022076	rcl1	100	78.342	Seriola_lalandi_dorsalis
ENSG00000120158	RCL1	96	30.660	ENSSARG00000013993	RTCA	64	30.660	Sorex_araneus
ENSG00000120158	RCL1	100	96.744	ENSSARG00000009260	RCL1	100	96.247	Sorex_araneus
ENSG00000120158	RCL1	100	90.233	ENSSPUG00000016330	RCL1	100	88.204	Sphenodon_punctatus
ENSG00000120158	RCL1	100	82.407	ENSSPAG00000018038	rcl1	100	80.214	Stegastes_partitus
ENSG00000120158	RCL1	100	99.070	ENSSSCG00000005217	RCL1	83	98.123	Sus_scrofa
ENSG00000120158	RCL1	100	85.067	ENSTGUG00000005138	RCL1	100	85.067	Taeniopygia_guttata
ENSG00000120158	RCL1	100	81.019	ENSTRUG00000010493	rcl1	99	78.649	Takifugu_rubripes
ENSG00000120158	RCL1	100	79.630	ENSTNIG00000013214	rcl1	99	77.507	Tetraodon_nigroviridis
ENSG00000120158	RCL1	100	97.209	ENSTBEG00000016339	RCL1	100	90.885	Tupaia_belangeri
ENSG00000120158	RCL1	100	96.783	ENSTTRG00000016525	RCL1	100	96.783	Tursiops_truncatus
ENSG00000120158	RCL1	100	97.674	ENSUAMG00000005598	RCL1	100	97.587	Ursus_americanus
ENSG00000120158	RCL1	100	96.744	ENSUMAG00000017890	RCL1	97	96.636	Ursus_maritimus
ENSG00000120158	RCL1	100	98.605	ENSVPAG00000009188	RCL1	100	98.165	Vicugna_pacos
ENSG00000120158	RCL1	100	97.209	ENSVVUG00000007304	RCL1	89	96.646	Vulpes_vulpes
ENSG00000120158	RCL1	100	75.401	ENSXETG00000000592	rcl1	100	75.401	Xenopus_tropicalis
ENSG00000120158	RCL1	100	81.481	ENSXCOG00000004922	rcl1	99	79.189	Xiphophorus_couchianus
ENSG00000120158	RCL1	59	30.455	ENSXCOG00000008002	rtca	63	30.455	Xiphophorus_couchianus
ENSG00000120158	RCL1	100	81.481	ENSXMAG00000022366	RCL1	99	79.189	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	-	IEA	Process
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	-	IEA	Process
GO:0004521	endoribonuclease activity	21873635.	IBA	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0008150	biological_process	-	ND	Process

EuRBPDB

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.