EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21676486	Expression and function of retinoblastoma binding protein 6 (RBBP6) in human lung cancer.	Immunobiology	2011 Oct	Motadi LR	doi: 10.1016/j.imbio.2011.05.004
24703106	Silencing RBBP6 (Retinoblastoma Binding Protein 6) sensitises breast cancer cells MCF7 to staurosporine and camptothecin-induced cell death.	Immunobiology	2014 Aug	Moela P	doi: 10.1016/j.imbio.2014.03.002
29369481	RBBP6 increases radioresistance and serves as a therapeutic target for preoperative radiotherapy in colorectal cancer.	Cancer Sci	2018 Apr	Xiao C	doi: 10.1111/cas.13516

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr16	24569549	Missense_Mutation	novel	L953F	0.45
ACC	chr16	24571509	Missense_Mutation	novel	E1481D	0.25
BLCA	chr16	24571350	Missense_Mutation	novel	E1428D	0.3
BLCA	chr16	24570970	Missense_Mutation	novel	D1302H	0.21
BLCA	chr16	24572061	Silent	novel	L1665L	0.31
BLCA	chr16	24571660	Missense_Mutation	NA	S1532G	0.2
BLCA	chr16	24561705	Missense_Mutation	NA	F314C	0.08
BLCA	chr16	24571186	Missense_Mutation	novel	Q1374E	0.2
BLCA	chr16	24559578	Missense_Mutation	novel	D250H	0.25
BLCA	chr16	24555854	Silent	novel	P157P	0.91
BLCA	chr16	24572061	Silent	novel	L1665L	0.06
BLCA	chr16	24555905	Silent	novel	C174C	0.59
BLCA	chr16	24571667	Missense_Mutation	rs763378882	S1534Y	0.51
BLCA	chr16	24567331	Missense_Mutation	rs144821029	P593L	0.7
BLCA	chr16	24555645	Missense_Mutation	NA	E127K	0.15
BLCA	chr16	24555679	Missense_Mutation	novel	S138C	0.28
BLCA	chr16	24555692	Nonsense_Mutation	novel	Y142*	0.1
BLCA	chr16	24569428	Frame_Shift_Ins	novel	*T914Lfs10**	0.08
BLCA	chr16	24569430	Frame_Shift_Ins	novel	*T914Ifs12**	0.08
BLCA	chr16	24569263	Missense_Mutation	NA	E858G	0.37
BLCA	chr16	24571336	Nonsense_Mutation	novel	Q1424*	0.36
BLCA	chr16	24567249	Missense_Mutation	NA	P566S	0.2
BLCA	chr16	24571126	Missense_Mutation	novel	T1354A	0.13
BLCA	chr16	24571720	Missense_Mutation	NA	K1552E	0.26
BLCA	chr16	24570068	Missense_Mutation	novel	K1126N	0.53
BLCA	chr16	24572069	Missense_Mutation	novel	K1668R	0.54
BLCA	chr16	24553512	Splice_Site	NA	X102_splice	0.21
BLCA	chr16	24571137	Silent	novel	S1357S	0.41
BLCA	chr16	24571679	Missense_Mutation	novel	R1538T	0.22
BRCA	chr16	24563297	Splice_Site	NA	X462_splice	0.16
BRCA	chr16	24555359	Intron	novel		0.14
BRCA	chr16	24553516	Missense_Mutation	novel	D103H	0.05
BRCA	chr16	24569194	Frame_Shift_Del	novel	*R835Kfs60**	0.07
BRCA	chr16	24567173	In_Frame_Del	novel	R541_S542del	0.54
BRCA	chr16	24567175	Missense_Mutation	NA	R541T	0.33
BRCA	chr16	24567829	Missense_Mutation	NA	D664N	0.18
BRCA	chr16	24568910	Missense_Mutation	novel	K740N	0.08
BRCA	chr16	24555394	Intron	novel		0.27
BRCA	chr16	24549112	Intron	novel		0.17
BRCA	chr16	24571167	Missense_Mutation	rs750648345	S1367R	0.33
BRCA	chr16	24569329	Missense_Mutation	novel	R880T	0.12
BRCA	chr16	24571044	In_Frame_Del	novel	S1328_E1329del	0.2
BRCA	chr16	24549032	Intron	NA		0.1
BRCA	chr16	24568747	Missense_Mutation	novel	S686Y	0.23
BRCA	chr16	24555869	Silent	NA	F162F	0.24
BRCA	chr16	24563236	Missense_Mutation	rs774633010	A443S	0.22
BRCA	chr16	24569925	Missense_Mutation	NA	Q1079E	0.11
BRCA	chr16	24571562	Missense_Mutation	NA	D1499G	0.29
BRCA	chr16	24555840	Missense_Mutation	NA	G153R	0.16
BRCA	chr16	24568947	Missense_Mutation	novel	Y753N	0.12
BRCA	chr16	24567489	Nonsense_Mutation	NA	R646*	0.39
CESC	chr16	24571573	Frame_Shift_Ins	novel	*R1503Lfs61**	0.17
CESC	chr16	24559564	Missense_Mutation	novel	S245Y	0.36
CESC	chr16	24561664	Silent	novel	H300H	0.26
CESC	chr16	24546174	Missense_Mutation	NA	D60N	0.25
CESC	chr16	24567182	Silent	NA	Q543Q	0.48
COAD	chr16	24569868	Frame_Shift_Del	NA	*A1062Pfs49**	0.3
COAD	chr16	24572063	Missense_Mutation	novel	K1666T	0.37
COAD	chr16	24569949	Frame_Shift_Ins	novel	*R1089Qfs6**	0.18
COAD	chr16	24569465	Silent	novel	P925P	0.33
COAD	chr16	24540483	5'UTR	novel		0.33
COAD	chr16	24571204	Missense_Mutation	rs755614989	V1380M	0.29
COAD	chr16	24555879	Missense_Mutation	novel	K166E	0.35	zf-CCHC_2
COAD	chr16	24555632	Silent	novel	E122E	0.39
COAD	chr16	24571229	Missense_Mutation	novel	E1388A	0.37
COAD	chr16	24570045	Missense_Mutation	NA	K1119E	0.11
COAD	chr16	24561910	Silent	rs747859597	P346P	0.29
COAD	chr16	24571483	Frame_Shift_Del	NA	*T1475Lfs20**	0.3
COAD	chr16	24569068	Missense_Mutation	rs371006887	R793H	0.07
COAD	chr16	24572345	Missense_Mutation	NA	S1760N	0.17
COAD	chr16	24568876	Missense_Mutation	NA	R729Q	0.26
COAD	chr16	24569868	Frame_Shift_Del	NA	*A1062Pfs49**	0.3
COAD	chr16	24567175	Missense_Mutation	novel	R541I	0.35
COAD	chr16	24570222	Missense_Mutation	NA	P1178S	0.31
COAD	chr16	24571360	Frame_Shift_Ins	novel	*D1432Vfs9**	0.04
COAD	chr16	24549136	Intron	novel		0.21
COAD	chr16	24571113	Frame_Shift_Del	NA	*N1351Mfs9**	0.45
COAD	chr16	24569501	Frame_Shift_Del	novel	*R939Efs11**	0.32
DLBC	chr16	24546197	Missense_Mutation	novel	N67K	0.29
ESCA	chr16	24571367	Missense_Mutation	novel	L1434Q	0.29
ESCA	chr16	24571900	Missense_Mutation	novel	V1612I	0.17
ESCA	chr16	24572569	3'UTR	novel		0.1
ESCA	chr16	24572649	3'UTR	novel		0.21
ESCA	chr16	24570365	Missense_Mutation	rs767099633	I1225M	0.19
ESCA	chr16	24569885	Silent	novel	E1065E	0.43
ESCA	chr16	24567390	Missense_Mutation	novel	T613A	0.4
GBM	chr16	24570448	Missense_Mutation	novel	R1253Q	0.29
GBM	chr16	24571606	Missense_Mutation	NA	K1514Q	0.57
GBM	chr16	24570167	Frame_Shift_Del	novel	F1160*	0.46
GBM	chr16	24546199	Missense_Mutation	novel	S68Y	0.47
GBM	chr16	24568963	Missense_Mutation	rs370877300	S758L	0.22
GBM	chr16	24570234	Missense_Mutation	rs562711301	R1182C	0.23
GBM	chr16	24568772	Silent	novel	S694S	0.5
GBM	chr16	24540788	Silent	NA	K54K	0.72
GBM	chr16	24570904	Missense_Mutation	rs149805045	R1280W	0.11
GBM	chr16	24569934	Frame_Shift_Ins	novel	*I1084Nfs11**	0.26
GBM	chr16	24569791	Missense_Mutation	rs199891868	I1034T	0.5
HNSC	chr16	24569234	Silent	novel	G848G	0.19
HNSC	chr16	24569543	Silent	novel	P951P	0.19
HNSC	chr16	24568751	Silent	novel	K687K	0.3
HNSC	chr16	24570424	Missense_Mutation	novel	E1245A	0.26
HNSC	chr16	24555871	Missense_Mutation	novel	R163H	0.35	zf-CCHC_2
HNSC	chr16	24571390	Missense_Mutation	novel	S1442C	0.03
HNSC	chr16	24540667	Missense_Mutation	novel	Y14C	0.22
HNSC	chr16	24540696	Missense_Mutation	novel	I24V	0.22
HNSC	chr16	24567217	Missense_Mutation	novel	V555G	0.23
KICH	chr16	24571639	Frame_Shift_Del	novel	*G1525Efs37**	0.37
KIRC	chr16	24553553	Missense_Mutation	novel	T115K	0.17
KIRC	chr16	24572489	3'UTR	novel		0.34
KIRC	chr16	24540640	Frame_Shift_Ins	novel	*Y6Lfs2**	0.27
KIRC	chr16	24571574	Missense_Mutation	rs780815708	R1503Q	0.37
KIRC	chr16	24570396	Missense_Mutation	NA	E1236K	0.27
KIRP	chr16	24569758	Missense_Mutation	NA	N1023I	0.36
KIRP	chr16	24570172	Missense_Mutation	NA	E1161V	0.35
KIRP	chr16	24570937	Missense_Mutation	NA	T1291P	0.43
KIRP	chr16	24567198	Missense_Mutation	novel	S549P	0.29
KIRP	chr16	24571622	Missense_Mutation	NA	R1519T	0.2
LAML	chr16	24570876	Missense_Mutation	novel	S1270R	0.08
LAML	chr16	24555359	Intron	novel		1
LAML	chr16	24540626	5'UTR	novel		0.12
LAML	chr16	24569180	Missense_Mutation	novel	W830C	0.05
LAML	chr16	24569543	Frame_Shift_Del	novel	*E952Sfs3**	0.03
LAML	chr16	24571313	Missense_Mutation	NA	P1416R	0.04
LGG	chr16	24556425	Nonsense_Mutation	novel	Y218*	0.23
LGG	chr16	24570000	Frame_Shift_Del	novel	*P1104Qfs7**	0.41
LGG	chr16	24540566	5'UTR	novel		0.33
LGG	chr16	24556360	Missense_Mutation	novel	R196I	0.41
LGG	chr16	24567178	Nonsense_Mutation	novel	S542*	0.35
LGG	chr16	24569800	Missense_Mutation	novel	P1037H	0.47
LGG	chr16	24572231	Frame_Shift_Del	novel	*Q1724Gfs18**	0.26
LGG	chr16	24571645	Missense_Mutation	novel	G1527R	0.37
LGG	chr16	24571387	Frame_Shift_Del	novel	*L1443Vfs8**	0.26
LIHC	chr16	24569158	Frame_Shift_Del	novel	*E825Nfs70**	0.38
LIHC	chr16	24571720	Missense_Mutation	NA	K1552E	0.17
LIHC	chr16	24571858	Frame_Shift_Ins	novel	E1599*	0.21
LIHC	chr16	24567831	Missense_Mutation	NA	D664E	0.08
LIHC	chr16	24572297	Missense_Mutation	novel	H1744R	0.48
LUAD	chr16	24559632	Missense_Mutation	novel	D268H	0.07
LUAD	chr16	24571136	Missense_Mutation	novel	S1357L	0.12
LUAD	chr16	24569136	Missense_Mutation	NA	V816I	0.25
LUAD	chr16	24572127	Frame_Shift_Del	novel	*S1688Afs100**	0.35
LUAD	chr16	24569040	Frame_Shift_Del	novel	R784*	0.37
LUAD	chr16	24555690	Missense_Mutation	novel	Y142N	0.15
LUAD	chr16	24568950	Missense_Mutation	rs543399143	H754Y	0.18
LUAD	chr16	24571602	Frame_Shift_Del	novel	*K1514Qfs47**	0.17
LUAD	chr16	24555611	Splice_Region	novel		0.31
LUAD	chr16	24569301	Missense_Mutation	novel	R871W	0.45
LUAD	chr16	24567280	Missense_Mutation	novel	P576L	0.25
LUAD	chr16	24567185	Missense_Mutation	NA	R544S	0.18
LUAD	chr16	24571978	Nonsense_Mutation	novel	E1638*	0.35
LUAD	chr16	24571045	Nonsense_Mutation	NA	E1327*	0.58
LUAD	chr16	24570982	Missense_Mutation	NA	P1306S	0.26
LUAD	chr16	24562160	Missense_Mutation	rs748181118	R430W	0.22
LUAD	chr16	24570469	Missense_Mutation	NA	G1260V	0.42
LUAD	chr16	24570988	Nonsense_Mutation	NA	E1308*	0.11
LUAD	chr16	24571390	Missense_Mutation	novel	S1442C	0.07
LUAD	chr16	24540662	Silent	novel	L12L	0.19
LUAD	chr16	24553542	Silent	novel	L111L	0.08
LUAD	chr16	24553543	Missense_Mutation	novel	A112S	0.08
LUAD	chr16	24569262	Missense_Mutation	NA	E858K	0.11
LUAD	chr16	24571520	Missense_Mutation	novel	S1485Y	0.19
LUSC	chr16	24567241	Missense_Mutation	novel	P563L	0.28
LUSC	chr16	24569760	Missense_Mutation	novel	D1024N	0.2
LUSC	chr16	24572160	Silent	NA	V1698V	0.22
LUSC	chr16	24561823	Splice_Site	NA	X318_splice	0.25
LUSC	chr16	24561824	Missense_Mutation	novel	A318S	0.25
LUSC	chr16	24571366	Missense_Mutation	rs768495546	L1434V	0.18
LUSC	chr16	24567336	Missense_Mutation	novel	A595S	0.29
LUSC	chr16	24553512	Splice_Site	NA	X102_splice	0.08
LUSC	chr16	24570197	Missense_Mutation	NA	K1169N	0.42
LUSC	chr16	24567486	Missense_Mutation	novel	Q645E	0.66
LUSC	chr16	24568896	Missense_Mutation	novel	R736G	0.34
LUSC	chr16	24572002	Missense_Mutation	novel	S1646G	0.3
LUSC	chr16	24555843	Missense_Mutation	NA	P154S	0.23
LUSC	chr16	24571139	Missense_Mutation	NA	N1358S	0.32
LUSC	chr16	24567398	Missense_Mutation	novel	W615C	0.26
LUSC	chr16	24561855	Missense_Mutation	rs368305107	Y328C	0.79
LUSC	chr16	24569217	Missense_Mutation	novel	K843E	0.34
LUSC	chr16	24561686	Missense_Mutation	novel	A308S	0.22
LUSC	chr16	24555622	Missense_Mutation	novel	N119S	0.06
LUSC	chr16	24569840	Missense_Mutation	novel	E1050D	0.22
LUSC	chr16	24571077	Missense_Mutation	rs757556265	Q1337H	0.49
OV	chr16	24540688	Missense_Mutation	novel	G21E	0.07
OV	chr16	24540570	5'UTR	novel		0.2
OV	chr16	24571248	Silent	NA	N1394N	0.27
OV	chr16	24555359	Intron	novel		0.25
OV	chr16	24569988	Nonsense_Mutation	NA	Q1100*	0.26
OV	chr16	24570324	Missense_Mutation	novel	N1212H	0.09
OV	chr16	24570086	Silent	rs758077429	K1132K	0.08
OV	chr16	24548950	Missense_Mutation	NA	R91Q	0.13
OV	chr16	24568856	Silent	novel	S722S	0.06
OV	chr16	24569440	Missense_Mutation	novel	K917R	0.17
OV	chr16	24555359	Intron	novel		0.16
OV	chr16	24555359	Intron	novel		1
OV	chr16	24571804	Frame_Shift_Del	novel	*K1580Rfs6**	0.13
OV	chr16	24555359	Intron	novel		0.14
PAAD	chr16	24549021	Intron	novel		0.28
PAAD	chr16	24563244	Missense_Mutation	novel	E445D	0.03
PAAD	chr16	24570158	Silent	rs760944143	V1156V	0.06
PAAD	chr16	24570301	Missense_Mutation	rs760684099	A1204V	0.18
PAAD	chr16	24568849	Missense_Mutation	novel	S720I	0.07
PRAD	chr16	24556373	Missense_Mutation	NA	M200I	0.18
PRAD	chr16	24563653	Silent	NA	P503P	0.22
PRAD	chr16	24571654	Frame_Shift_Del	novel	*S1532Vfs30**	0.3
READ	chr16	24571462	Missense_Mutation	NA	D1466Y	0.3
READ	chr16	24571685	Missense_Mutation	novel	R1540K	0.19
READ	chr16	24567477	Missense_Mutation	novel	Y642H	0.53
READ	chr16	24571633	Frame_Shift_Del	NA	*G1525Efs37**	0.21
READ	chr16	24571603	Missense_Mutation	novel	N1513H	0.15
READ	chr16	24567160	Missense_Mutation	novel	R536Q	0.41
READ	chr16	24567449	Missense_Mutation	novel	Q632H	0.39
READ	chr16	24569875	Missense_Mutation	NA	A1062V	0.42
READ	chr16	24571381	Missense_Mutation	novel	N1439H	0.41
READ	chr16	24549057	Intron	novel		0.19
READ	chr16	24561864	Missense_Mutation	novel	R331I	0.38
READ	chr16	24567501	Nonsense_Mutation	NA	E650*	0.47
READ	chr16	24570292	Missense_Mutation	rs770698834	S1201Y	0.16
SARC	chr16	24572017	Missense_Mutation	novel	S1651T	0.38
SARC	chr16	24569772	Missense_Mutation	novel	V1028L	0.09
SARC	chr16	24571862	Frame_Shift_Del	novel	*E1601Sfs18**	0.46
SARC	chr16	24570193	Missense_Mutation	rs748441167	S1168L	0.44
SKCM	chr16	24569847	Missense_Mutation	NA	P1053S	0.33
SKCM	chr16	24561951	Missense_Mutation	NA	S360F	0.22
SKCM	chr16	24564854	Silent	novel	R526R	0.25
SKCM	chr16	24571653	Silent	NA	S1529S	0.28
SKCM	chr16	24568831	Missense_Mutation	rs772826182	S714F	0.42
SKCM	chr16	24567276	Missense_Mutation	NA	P575S	0.12
SKCM	chr16	24569850	Nonsense_Mutation	NA	R1054*	0.43
SKCM	chr16	24571905	Silent	NA	K1613K	0.45
SKCM	chr16	24568974	Missense_Mutation	NA	P762S	0.13
SKCM	chr16	24567276	Missense_Mutation	NA	P575S	0.29
SKCM	chr16	24571440	Silent	novel	S1458S	0.08
SKCM	chr16	24562038	Missense_Mutation	NA	S389F	0.05
SKCM	chr16	24569848	Missense_Mutation	NA	P1053L	0.56
SKCM	chr16	24570169	Missense_Mutation	NA	F1160C	0.08
SKCM	chr16	24571923	Missense_Mutation	NA	S1619R	0.07
SKCM	chr16	24568829	Silent	novel	R713R	0.27
SKCM	chr16	24571771	Missense_Mutation	rs191159591	R1569C	0.24
SKCM	chr16	24572142	Silent	novel	S1692S	0.47
SKCM	chr16	24569247	Missense_Mutation	novel	P853S	0.19
SKCM	chr16	24562160	Missense_Mutation	rs748181118	R430W	0.33
SKCM	chr16	24562016	Missense_Mutation	rs149108517	P382S	0.41
SKCM	chr16	24567351	Missense_Mutation	NA	P600S	0.07
SKCM	chr16	24568981	Missense_Mutation	NA	R764K	0.1
SKCM	chr16	24569855	Frame_Shift_Del	novel	*E1056Nfs55**	0.28
SKCM	chr16	24569040	Missense_Mutation	rs146591085	R784C	0.39
SKCM	chr16	24567357	Missense_Mutation	NA	P602S	0.45
SKCM	chr16	24567366	Missense_Mutation	NA	P605S	0.18
SKCM	chr16	24567270	Missense_Mutation	NA	P573S	0.38
SKCM	chr16	24568885	Missense_Mutation	NA	P732L	0.24
SKCM	chr16	24571771	Missense_Mutation	rs191159591	R1569C	0.1
SKCM	chr16	24570443	Silent	NA	V1251V	0.23
SKCM	chr16	24571133	Missense_Mutation	novel	P1356L	0.52
SKCM	chr16	24568755	Missense_Mutation	novel	P689S	0.36
SKCM	chr16	24563637	Missense_Mutation	novel	P498L	0.27
SKCM	chr16	24567463	Missense_Mutation	NA	S637F	0.36
SKCM	chr16	24571759	Missense_Mutation	NA	P1565S	0.19
SKCM	chr16	24571379	Missense_Mutation	rs759584684	G1438E	0.16
SKCM	chr16	24571472	Missense_Mutation	NA	P1469L	0.17
SKCM	chr16	24569724	Missense_Mutation	novel	P1012S	0.31
SKCM	chr16	24567351	Missense_Mutation	novel	P600T	0.33
SKCM	chr16	24567874	Missense_Mutation	rs757145338	R679C	0.24
SKCM	chr16	24555624	Silent	NA	L120L	0.5
SKCM	chr16	24555869	Silent	NA	F162F	0.28
SKCM	chr16	24570999	Silent	NA	I1311I	0.35
SKCM	chr16	24567403	Missense_Mutation	NA	S617L	0.2
STAD	chr16	24568822	Missense_Mutation	rs758145892	R711H	0.24
STAD	chr16	24571421	Missense_Mutation	rs138495629	T1452M	0.34
STAD	chr16	24567798	Missense_Mutation	novel	K653N	0.25
STAD	chr16	24569230	Missense_Mutation	rs767988268	A847V	0.09
STAD	chr16	24570344	Missense_Mutation	NA	K1218N	0.19
STAD	chr16	24568828	Missense_Mutation	NA	R713H	0.21
STAD	chr16	24571778	Missense_Mutation	NA	K1571T	0.21
STAD	chr16	24571669	Missense_Mutation	novel	S1535G	0.32
STAD	chr16	24570460	Missense_Mutation	NA	G1257E	0.24
STAD	chr16	24540709	Missense_Mutation	NA	D28A	0.32
STAD	chr16	24567356	Silent	NA	P601P	0.36
STAD	chr16	24567336	Missense_Mutation	rs199538396	A595T	0.41
STAD	chr16	24567506	Splice_Site	novel	X651_splice	0.42
STAD	chr16	24570980	Missense_Mutation	rs148664608	A1305V	0.36
STAD	chr16	24571561	Missense_Mutation	novel	D1499N	0.28
STAD	chr16	24567224	Silent	NA	V557V	0.07
STAD	chr16	24569774	Silent	NA	V1028V	0.22
STAD	chr16	24570269	Silent	NA	R1193R	0.12
STAD	chr16	24571875	Frame_Shift_Ins	novel	*T1604Nfs5**	0.14
STAD	chr16	24569431	Missense_Mutation	novel	T914R	0.09
STAD	chr16	24555862	Missense_Mutation	rs770951060	T160M	0.06	zf-CCHC_2
STAD	chr16	24568954	Missense_Mutation	rs199798897	R755Q	0.2
STAD	chr16	24568774	Missense_Mutation	NA	Y695C	0.26
STAD	chr16	24571483	Frame_Shift_Del	NA	*T1475Lfs20**	0.19
STAD	chr16	24571300	Nonsense_Mutation	novel	E1412*	0.16
STAD	chr16	24569430	Missense_Mutation	NA	T914A	0.16
STAD	chr16	24569970	Missense_Mutation	NA	K1094E	0.12
STAD	chr16	24567874	Missense_Mutation	rs757145338	R679C	0.09
STAD	chr16	24571483	Frame_Shift_Del	NA	*T1475Lfs20**	0.35
STAD	chr16	24556447	Missense_Mutation	NA	A225V	0.09
STAD	chr16	24572204	Missense_Mutation	rs374147465	S1713N	0.41
TGCT	chr16	24556367	Frame_Shift_Del	novel	*F198Lfs2**	0.11
THCA	chr16	24556431	Missense_Mutation	novel	I220V	0.31
THCA	chr16	24571117	In_Frame_Ins	novel	N1351delinsRITKY	0.07
THCA	chr16	24564859	Nonsense_Mutation	novel	C528*	0.19
THCA	chr16	24564860	Frame_Shift_Ins	novel	*Y529Lfs70**	0.13
THCA	chr16	24569428	Frame_Shift_Ins	novel	*T914Lfs10**	0.23
THCA	chr16	24569430	Frame_Shift_Ins	novel	*T914Ifs12**	0.23
THCA	chr16	24569428	In_Frame_Ins	novel	N913_T914insLYNIF	0.08
THCA	chr16	24569699	Frame_Shift_Ins	novel	*K1004Tfs33**	0.42
THCA	chr16	24569921	In_Frame_Ins	novel	S1077_S1078insVWF	0.06
THCA	chr16	24569923	Missense_Mutation	novel	S1078Y	0.02
THYM	chr16	24569393	Frame_Shift_Del	novel	*K901Nfs49**	0.11
THYM	chr16	24570169	Frame_Shift_Del	novel	*E1161Lfs3**	0.13
UCEC	chr16	24563483	Nonsense_Mutation	NA	Q483*	0.49
UCEC	chr16	24549218	Intron	novel		0.28
UCEC	chr16	24556313	Missense_Mutation	NA	K180N	0.4
UCEC	chr16	24540502	5'UTR	novel		0.48
UCEC	chr16	24563278	Missense_Mutation	rs765269870	A457T	0.3
UCEC	chr16	24568953	Nonsense_Mutation	NA	R755*	0.15
UCEC	chr16	24569140	Missense_Mutation	NA	D817A	0.28
UCEC	chr16	24571620	Missense_Mutation	NA	E1518D	0.3
UCEC	chr16	24540716	Missense_Mutation	novel	K30N	0.12
UCEC	chr16	24569703	Missense_Mutation	novel	D1005Y	0.43
UCEC	chr16	24570235	Missense_Mutation	rs116616570	R1182H	0.23
UCEC	chr16	24571072	Missense_Mutation	novel	T1336A	0.4
UCEC	chr16	24572387	Missense_Mutation	novel	K1774T	0.37
UCEC	chr16	24572553	3'UTR	novel		0.33
UCEC	chr16	24540587	5'UTR	novel		0.44
UCEC	chr16	24555863	Silent	rs140732312	T160T	0.32
UCEC	chr16	24561885	Missense_Mutation	NA	P338H	0.23
UCEC	chr16	24570935	Missense_Mutation	NA	R1290Q	0.39
UCEC	chr16	24572271	Missense_Mutation	NA	K1735N	0.33
UCEC	chr16	24570029	Missense_Mutation	novel	D1113E	0.29
UCEC	chr16	24571221	Missense_Mutation	rs779589665	I1385M	0.36
UCEC	chr16	24570378	Nonsense_Mutation	NA	E1230*	0.38
UCEC	chr16	24572611	3'UTR	novel		0.5
UCEC	chr16	24569020	Missense_Mutation	novel	R777M	0.36
UCEC	chr16	24572271	Missense_Mutation	NA	K1735N	0.26
UCEC	chr16	24569584	Missense_Mutation	rs773916079	G965D	0.38
UCEC	chr16	24570287	Silent	novel	K1199K	0.4
UCEC	chr16	24572084	Missense_Mutation	rs535785282	A1673V	0.3
UCEC	chr16	24555692	Silent	rs763639576	Y142Y	0.3
UCEC	chr16	24540623	5'UTR	novel		0.43
UCEC	chr16	24571363	Missense_Mutation	NA	R1433C	0.16
UCEC	chr16	24571667	Missense_Mutation	rs763378882	S1534Y	0.13
UCEC	chr16	24569364	Nonsense_Mutation	NA	R892*	0.19
UCEC	chr16	24571905	Silent	NA	K1613K	0.2
UCEC	chr16	24555674	Silent	rs559784053	S136S	0.17
UCEC	chr16	24563635	Silent	novel	R497R	0.09
UCEC	chr16	24568954	Missense_Mutation	rs199798897	R755Q	0.26
UCEC	chr16	24571054	Missense_Mutation	NA	E1330K	0.34
UCEC	chr16	24571515	Silent	novel	S1483S	0.04
UCEC	chr16	24572129	Missense_Mutation	novel	S1688I	0.27
UCEC	chr16	24569167	Missense_Mutation	rs367639774	R826H	0.1
UCEC	chr16	24572364	Missense_Mutation	novel	K1766N	0.45
UCEC	chr16	24562018	Silent	rs768823495	P382P	0.41
UCEC	chr16	24568877	Silent	novel	R729R	0.08
UCEC	chr16	24570475	Missense_Mutation	NA	S1262I	0.5
UCEC	chr16	24570934	Nonsense_Mutation	NA	R1290*	0.46
UCEC	chr16	24569014	Missense_Mutation	rs368671422	A775V	0.37
UCEC	chr16	24570309	Frame_Shift_Del	NA	*I1209Sfs47**	0.56
UCEC	chr16	24562084	Nonsense_Mutation	novel	*A405Lfs4**	0.04
UCEC	chr16	24561865	In_Frame_Del	NA	L332del	0.39
UCEC	chr16	24548950	Missense_Mutation	NA	R91Q	0.27
UCEC	chr16	24567501	Nonsense_Mutation	NA	E650*	0.59
UCEC	chr16	24555370	Intron	novel		0.33
UCEC	chr16	24569491	Missense_Mutation	novel	K934R	0.38
UCEC	chr16	24569890	Missense_Mutation	NA	P1067L	0.65
UCEC	chr16	24570345	Missense_Mutation	novel	I1219V	0.41
UCEC	chr16	24570497	Splice_Region	novel	T1269T	0.08
UCEC	chr16	24569014	Missense_Mutation	rs368671422	A775V	0.43
UCEC	chr16	24569764	Missense_Mutation	novel	G1025E	0.37
UCEC	chr16	24540470	5'UTR	novel		0.32
UCEC	chr16	24570309	Frame_Shift_Del	NA	*I1209Sfs47**	0.41
UCEC	chr16	24571653	Frame_Shift_Ins	novel	*S1532Kfs2**	0.27
UCEC	chr16	24567490	Missense_Mutation	rs751022695	R646Q	0.4
UCEC	chr16	24570378	Nonsense_Mutation	NA	E1230*	0.24
UCEC	chr16	24570916	Nonsense_Mutation	NA	E1284*	0.4
UCEC	chr16	24571582	Missense_Mutation	novel	D1506Y	0.67
UCEC	chr16	24567420	Missense_Mutation	novel	A623T	0.29
UCEC	chr16	24572295	Silent	novel	K1743K	0.21
UCEC	chr16	24555674	Silent	rs559784053	S136S	0.62
UCEC	chr16	24559568	Silent	novel	S246S	0.53
UCEC	chr16	24569541	Missense_Mutation	novel	P951T	0.44
UCEC	chr16	24561848	Missense_Mutation	NA	T326A	0.41
UCEC	chr16	24549078	Intron	novel		0.35
UCEC	chr16	24571633	Frame_Shift_Del	NA	*G1525Efs37**	0.43
UCEC	chr16	24563631	Missense_Mutation	NA	A496V	0.35
UCEC	chr16	24546228	Nonsense_Mutation	novel	G78*	0.3
UCEC	chr16	24568771	Missense_Mutation	rs754328844	S694L	0.3
UCEC	chr16	24570187	Missense_Mutation	novel	K1166R	0.4
UCEC	chr16	24562112	In_Frame_Ins	novel	A414delinsVLSS	0.07
UCEC	chr16	24562114	Silent	novel	A414A	0.05
UCEC	chr16	24569851	Missense_Mutation	rs376526154	R1054Q	0.24
UCEC	chr16	24571667	Missense_Mutation	rs763378882	S1534Y	0.33
UCEC	chr16	24568839	Frame_Shift_Ins	novel	*R717Lfs100**	0.03
UCEC	chr16	24569890	Missense_Mutation	NA	P1067L	0.2
UCEC	chr16	24571482	Frame_Shift_Ins	rs747289496	*T1475Nfs2**	0.33
UCEC	chr16	24569752	Missense_Mutation	rs756879107	R1021Q	0.35
UCEC	chr16	24570286	Missense_Mutation	novel	K1199T	0.38
UCEC	chr16	24572359	Frame_Shift_Ins	novel	*H1765Qfs12**	0.18
UCEC	chr16	24567870	Missense_Mutation	novel	K677N	0.39
UCEC	chr16	24561870	Missense_Mutation	novel	R333Q	0.43
UCEC	chr16	24567874	Missense_Mutation	rs757145338	R679C	0.21
UCEC	chr16	24571771	Missense_Mutation	rs191159591	R1569C	0.35
UCEC	chr16	24572081	Missense_Mutation	novel	K1672T	0.35
UCEC	chr16	24555570	Intron	novel		0.37
UCEC	chr16	24567175	Missense_Mutation	novel	R541I	0.31
UCEC	chr16	24570949	Missense_Mutation	novel	T1295A	0.52
UCEC	chr16	24572611	3'UTR	novel		0.19
UCEC	chr16	24571483	Frame_Shift_Del	NA	*T1475Lfs20**	0.53
UCEC	chr16	24572421	Missense_Mutation	novel	Q1785H	0.42
UCEC	chr16	24569506	Missense_Mutation	novel	R939I	0.04
UCEC	chr16	24568966	Missense_Mutation	novel	R759T	0.08
UCEC	chr16	24570934	Nonsense_Mutation	NA	R1290*	0.42
UCEC	chr16	24567294	Missense_Mutation	novel	P581S	0.06
UCEC	chr16	24570934	Nonsense_Mutation	NA	R1290*	0.14
UCEC	chr16	24556448	Splice_Site	NA	X225_splice	0.44
UCEC	chr16	24553529	Missense_Mutation	rs368643832	A107V	0.28
UCEC	chr16	24567489	Nonsense_Mutation	NA	R646*	0.35
UCEC	chr16	24569224	Missense_Mutation	novel	Y845C	0.31
UCEC	chr16	24569212	Missense_Mutation	novel	Y841F	0.5
UCEC	chr16	24571113	Frame_Shift_Del	NA	*N1351Mfs9**	0.23
UCEC	chr16	24569777	Frame_Shift_Ins	novel	*E1032Rfs8**	0.41
UCEC	chr16	24571431	Silent	NA	K1455K	0.52
UCEC	chr16	24567501	Nonsense_Mutation	NA	E650*	0.17
UCEC	chr16	24572444	Frame_Shift_Del	novel		0.47
UCEC	chr16	24570916	Nonsense_Mutation	NA	E1284*	0.27
UCEC	chr16	24572026	Nonsense_Mutation	NA	E1654*	0.39
UCEC	chr16	24555580	Intron	novel		0.06
UCEC	chr16	24540718	Missense_Mutation	novel	K31T	0.17
UCEC	chr16	24546202	Missense_Mutation	novel	S69F	0.4
UCEC	chr16	24553527	Silent	rs141654910	S106S	0.33
UCEC	chr16	24567197	Silent	novel	P548P	0.18
UCEC	chr16	24568958	Silent	novel	S756S	0.14
UCEC	chr16	24569510	Silent	novel	R940R	0.2
UCEC	chr16	24569731	Missense_Mutation	novel	A1014V	0.16
UCEC	chr16	24572410	Missense_Mutation	novel	K1782Q	0.33
UCEC	chr16	24567501	Nonsense_Mutation	NA	E650*	0.41
UCEC	chr16	24572275	Missense_Mutation	novel	K1737E	0.4
UCEC	chr16	24548961	Missense_Mutation	NA	A95S	0.34
UCEC	chr16	24555359	Intron	novel		0.2
UCEC	chr16	24555820	Splice_Site	NA	X146_splice	0.28
UCEC	chr16	24561823	Splice_Site	NA	X318_splice	0.36
UCEC	chr16	24571154	Missense_Mutation	novel	P1363L	0.41
UCEC	chr16	24572051	Missense_Mutation	NA	S1662Y	0.33
UCEC	chr16	24555570	Intron	novel		0.34
UCEC	chr16	24570980	Missense_Mutation	rs148664608	A1305V	0.5
UCEC	chr16	24571818	Silent	novel	G1584G	0.27
UCS	chr16	24570042	Missense_Mutation	novel	V1118I	0.19
UCS	chr16	24548949	Nonsense_Mutation	novel	R91*	0.5
UCS	chr16	24555863	Silent	rs140732312	T160T	0.36
UCS	chr16	24571248	Missense_Mutation	novel	N1394K	0.48

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.0833	0.23475
GBM	DEL	0.1005	0.0057085

Survival Analysis

Cancer	P-value	Q-value
HNSC	0.037	Kaplan-Meier Survival Analysis
PRAD	0.045	Kaplan-Meier Survival Analysis
LUSC	0.037	Kaplan-Meier Survival Analysis
BLCA	0.035	Kaplan-Meier Survival Analysis
CESC	0.036	Kaplan-Meier Survival Analysis
READ	0.032	Kaplan-Meier Survival Analysis
GBM	0.027	Kaplan-Meier Survival Analysis
LIHC	0.014	Kaplan-Meier Survival Analysis
OV	0.025	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000122257 (Gene tree)
Gene ID: 5930
Gene Symbol: RBBP6
Alias: P2P-R|PACT|SNAMA
Full Name: RB binding protein 6, ubiquitin ligase
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 35,171 bases
Position: chr16:24,537,693-24,572,863
Accession: 9889
RBP type: canonical RBP
Summary: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000481477	zf-CCHC_2	PF13696.6	1.5e-09	1	1
ENSP00000457716	zf-CCHC_2	PF13696.6	4.4e-09	1	1
ENSP00000316291	zf-CCHC_2	PF13696.6	1.4e-08	1	1
ENSP00000496720	zf-CCHC_2	PF13696.6	1.4e-08	1	1
ENSP00000317872	zf-CCHC_2	PF13696.6	1.5e-08	1	1
ENSP00000370427	zf-CCHC_2	PF13696.6	1.7e-08	1	1
ENSP00000456750	zf-CCHC_2	PF13696.6	1.8e-08	1	1
ENSP00000481477	zf-CCHC	PF00098.23	3e-05	1	1
ENSP00000457716	zf-CCHC	PF00098.23	8.2e-05	1	1
ENSP00000370427	zf-CCHC	PF00098.23	0.00014	1	1
ENSP00000456750	zf-CCHC	PF00098.23	0.00014	1	1
ENSP00000496720	zf-CCHC	PF00098.23	0.00025	1	1
ENSP00000316291	zf-CCHC	PF00098.23	0.00027	1	1
ENSP00000317872	zf-CCHC	PF00098.23	0.00028	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29084250	KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation.	PLoS Pathog	2017 Oct 30	Sharma NR	doi: 10.1371/journal.ppat.1006677
22578083	Discovery of novel glucose-regulated proteins in isolated human pancreatic islets using LC-MS/MS-based proteomics.	J Proteome Res	2012 Jul 6	Schrimpe-Rutledge AC	doi: 10.1021/pr3002996
9037032	The proliferation potential protein-related (P2P-R) gene with domains encoding heterogeneous nuclear ribonucleoprotein association and Rb1 binding shows repressed expression during terminal differentiation.	Proc Natl Acad Sci U S A	1997 Feb 18	Witte MM	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000568015	RBBP6-210	695	-	ENSP00000460821	158 (aa)	-	I3L3Y2
ENST00000319715	RBBP6-201	6840	-	ENSP00000317872	1792 (aa)	-	Q7Z6E9
ENST00000562430	RBBP6-205	6482	-	-	- (aa)	-	-
ENST00000452655	RBBP6-204	854	-	ENSP00000390537	118 (aa)	-	Q7Z6E9
ENST00000564726	RBBP6-208	514	-	-	- (aa)	-	-
ENST00000564314	RBBP6-207	3361	-	ENSP00000456750	1008 (aa)	-	H3BSK8
ENST00000567686	RBBP6-209	1138	-	ENSP00000457716	300 (aa)	-	H3BUN0
ENST00000568316	RBBP6-211	556	-	-	- (aa)	-	-
ENST00000613729	RBBP6-213	1946	-	-	- (aa)	-	-
ENST00000348022	RBBP6-202	5739	-	ENSP00000316291	1758 (aa)	-	Q7Z6E9
ENST00000646282	RBBP6-214	5332	-	ENSP00000496720	1759 (aa)	-	A0A2R8Y880
ENST00000381039	RBBP6-203	3384	-	ENSP00000370427	952 (aa)	-	Q7Z6E9
ENST00000570185	RBBP6-212	505	-	-	- (aa)	-	-
ENST00000562683	RBBP6-206	529	-	ENSP00000481477	138 (aa)	-	A0A087WY32

Gene Model

Click here to download ENSG00000122257's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000122257	von Willebrand Factor	5.46929428156633E-6	17903294
ENSG00000122257	von Willebrand Factor	4.2474517914842E-7	17903294
ENSG00000122257	Stroke	5.2457805E-004	19369658
ENSG00000122257	Galvanic Skin Response	7E-6	25387706
ENSG00000122257	Galvanic Skin Response	3E-6	25387706
ENSG00000122257	Motor Activity	9E-6	23251661

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000122257	rs7195386	16	24567137	A	Obesity-related traits	23251661	[NR] min/d increase	0.03	EFO_0003940
ENSG00000122257	rs7195386	16	24567137	C	Body mass index	28892062	[0.0091-0.0209] kg/m2 decrease	0.015	EFO_0004340
ENSG00000122257	rs7195386	16	24567137	T	Body mass index	30108127	[NR] unit increase	0.013	EFO_0004340
ENSG00000122257	rs7195386	16	24567137	?	Body mass index	30595370			EFO_0004340

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000122257's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000122257	RBBP6	100	98.667	ENSAMEG00000009312	RBBP6	98	92.351	Ailuropoda_melanoleuca
ENSG00000122257	RBBP6	97	97.761	ENSAPLG00000009569	RBBP6	94	72.209	Anas_platyrhynchos
ENSG00000122257	RBBP6	95	96.947	ENSACAG00000011794	RBBP6	100	70.446	Anolis_carolinensis
ENSG00000122257	RBBP6	100	100.000	ENSANAG00000037384	RBBP6	100	98.104	Aotus_nancymaae
ENSG00000122257	RBBP6	100	99.000	ENSBTAG00000009441	RBBP6	92	92.347	Bos_taurus
ENSG00000122257	RBBP6	100	99.107	ENSCJAG00000020661	RBBP6	100	97.490	Callithrix_jacchus
ENSG00000122257	RBBP6	100	98.667	ENSCAFG00000017566	RBBP6	98	94.432	Canis_familiaris
ENSG00000122257	RBBP6	99	98.529	ENSCAFG00020021283	-	93	99.010	Canis_lupus_dingo
ENSG00000122257	RBBP6	100	99.000	ENSCHIG00000013732	RBBP6	92	92.007	Capra_hircus
ENSG00000122257	RBBP6	100	99.667	ENSTSYG00000000822	RBBP6	100	98.148	Carlito_syrichta
ENSG00000122257	RBBP6	97	82.090	ENSCAPG00000012399	RBBP6	96	90.120	Cavia_aperea
ENSG00000122257	RBBP6	97	100.000	ENSCPOG00000040025	RBBP6	98	91.297	Cavia_porcellus
ENSG00000122257	RBBP6	100	100.000	ENSCCAG00000023229	RBBP6	100	99.306	Cebus_capucinus
ENSG00000122257	RBBP6	100	100.000	ENSCATG00000033601	RBBP6	100	99.306	Cercocebus_atys
ENSG00000122257	RBBP6	100	97.667	ENSCLAG00000009872	RBBP6	98	90.961	Chinchilla_lanigera
ENSG00000122257	RBBP6	100	100.000	ENSCSAG00000006609	RBBP6	100	98.828	Chlorocebus_sabaeus
ENSG00000122257	RBBP6	100	99.000	ENSCHOG00000000278	RBBP6	76	93.309	Choloepus_hoffmanni
ENSG00000122257	RBBP6	100	96.203	ENSCPBG00000001818	RBBP6	95	79.623	Chrysemys_picta_bellii
ENSG00000122257	RBBP6	100	100.000	ENSCANG00000039613	RBBP6	100	99.074	Colobus_angolensis_palliatus
ENSG00000122257	RBBP6	100	98.101	ENSCGRG00001017193	Rbbp6	93	91.545	Cricetulus_griseus_chok1gshd
ENSG00000122257	RBBP6	100	98.101	ENSCGRG00000011887	Rbbp6	93	91.545	Cricetulus_griseus_crigri
ENSG00000122257	RBBP6	100	99.000	ENSDNOG00000048802	RBBP6	100	94.200	Dasypus_novemcinctus
ENSG00000122257	RBBP6	97	100.000	ENSDORG00000010285	Rbbp6	96	90.153	Dipodomys_ordii
ENSG00000122257	RBBP6	99	98.529	ENSEASG00005017682	-	95	99.552	Equus_asinus_asinus
ENSG00000122257	RBBP6	99	98.529	ENSECAG00000014572	-	94	98.655	Equus_caballus
ENSG00000122257	RBBP6	97	100.000	ENSEEUG00000001683	RBBP6	94	91.571	Erinaceus_europaeus
ENSG00000122257	RBBP6	100	98.667	ENSFCAG00000043694	RBBP6	94	94.622	Felis_catus
ENSG00000122257	RBBP6	97	97.761	ENSFALG00000003750	RBBP6	95	69.729	Ficedula_albicollis
ENSG00000122257	RBBP6	100	98.667	ENSFDAG00000013132	RBBP6	98	92.504	Fukomys_damarensis
ENSG00000122257	RBBP6	100	96.667	ENSGALG00000006043	RBBP6	86	79.507	Gallus_gallus
ENSG00000122257	RBBP6	100	96.333	ENSGAGG00000004371	RBBP6	95	80.189	Gopherus_agassizii
ENSG00000122257	RBBP6	100	100.000	ENSGGOG00000007137	RBBP6	100	99.537	Gorilla_gorilla
ENSG00000122257	RBBP6	100	98.667	ENSHGLG00000008327	RBBP6	98	91.923	Heterocephalus_glaber_female
ENSG00000122257	RBBP6	97	99.254	ENSHGLG00100007773	RBBP6	98	86.505	Heterocephalus_glaber_male
ENSG00000122257	RBBP6	100	99.333	ENSSTOG00000016006	RBBP6	100	94.757	Ictidomys_tridecemlineatus
ENSG00000122257	RBBP6	97	100.000	ENSJJAG00000014549	Rbbp6	95	88.909	Jaculus_jaculus
ENSG00000122257	RBBP6	100	93.333	ENSLACG00000012333	RBBP6	94	60.944	Latimeria_chalumnae
ENSG00000122257	RBBP6	100	86.333	ENSLOCG00000005487	RBBP6	95	53.873	Lepisosteus_oculatus
ENSG00000122257	RBBP6	100	98.667	ENSLAFG00000009528	RBBP6	100	93.586	Loxodonta_africana
ENSG00000122257	RBBP6	100	100.000	ENSMFAG00000038627	RBBP6	100	99.537	Macaca_fascicularis
ENSG00000122257	RBBP6	100	100.000	ENSMMUG00000015908	RBBP6	100	99.537	Macaca_mulatta
ENSG00000122257	RBBP6	100	100.000	ENSMNEG00000033630	RBBP6	100	99.537	Macaca_nemestrina
ENSG00000122257	RBBP6	100	100.000	ENSMLEG00000030073	RBBP6	100	99.537	Mandrillus_leucophaeus
ENSG00000122257	RBBP6	97	98.507	ENSMGAG00000006423	RBBP6	96	72.026	Meleagris_gallopavo
ENSG00000122257	RBBP6	100	99.333	ENSMICG00000008059	RBBP6	100	98.611	Microcebus_murinus
ENSG00000122257	RBBP6	91	92.857	ENSMODG00000024435	-	97	88.263	Monodelphis_domestica
ENSG00000122257	RBBP6	91	88.095	ENSMODG00000024434	-	96	85.047	Monodelphis_domestica
ENSG00000122257	RBBP6	91	88.095	ENSMODG00000024432	-	96	84.579	Monodelphis_domestica
ENSG00000122257	RBBP6	100	83.699	ENSMODG00000016318	-	100	81.044	Monodelphis_domestica
ENSG00000122257	RBBP6	96	98.496	MGP_CAROLIEiJ_G0030424	-	100	95.844	Mus_caroli
ENSG00000122257	RBBP6	100	98.007	ENSMUSG00000030779	Rbbp6	98	88.619	Mus_musculus
ENSG00000122257	RBBP6	100	97.010	MGP_PahariEiJ_G0013634	Rbbp6	93	90.684	Mus_pahari
ENSG00000122257	RBBP6	100	98.007	MGP_SPRETEiJ_G0031538	Rbbp6	94	88.364	Mus_spretus
ENSG00000122257	RBBP6	100	98.667	ENSMPUG00000012318	RBBP6	92	91.605	Mustela_putorius_furo
ENSG00000122257	RBBP6	99	91.367	ENSMLUG00000024100	-	97	89.316	Myotis_lucifugus
ENSG00000122257	RBBP6	100	98.333	ENSMLUG00000010601	-	94	91.795	Myotis_lucifugus
ENSG00000122257	RBBP6	99	86.765	ENSMLUG00000022254	-	92	85.000	Myotis_lucifugus
ENSG00000122257	RBBP6	100	80.380	ENSMLUG00000027720	-	84	82.008	Myotis_lucifugus
ENSG00000122257	RBBP6	100	81.013	ENSMLUG00000026698	-	85	82.008	Myotis_lucifugus
ENSG00000122257	RBBP6	97	100.000	ENSNGAG00000002381	Rbbp6	92	89.116	Nannospalax_galili
ENSG00000122257	RBBP6	100	100.000	ENSNLEG00000011896	RBBP6	100	99.537	Nomascus_leucogenys
ENSG00000122257	RBBP6	100	81.646	ENSMEUG00000014491	RBBP6	88	81.447	Notamacropus_eugenii
ENSG00000122257	RBBP6	97	100.000	ENSOPRG00000016272	RBBP6	59	99.415	Ochotona_princeps
ENSG00000122257	RBBP6	97	99.254	ENSODEG00000012319	RBBP6	96	86.838	Octodon_degus
ENSG00000122257	RBBP6	100	88.304	ENSOANG00000007673	RBBP6	96	81.060	Ornithorhynchus_anatinus
ENSG00000122257	RBBP6	100	99.000	ENSOCUG00000004346	RBBP6	97	90.780	Oryctolagus_cuniculus
ENSG00000122257	RBBP6	100	99.667	ENSOGAG00000026986	RBBP6	100	96.488	Otolemur_garnettii
ENSG00000122257	RBBP6	100	99.000	ENSOARG00000017741	RBBP6	92	90.752	Ovis_aries
ENSG00000122257	RBBP6	100	99.425	ENSPPAG00000023595	RBBP6	100	97.879	Pan_paniscus
ENSG00000122257	RBBP6	100	98.667	ENSPPRG00000004074	RBBP6	94	94.504	Panthera_pardus
ENSG00000122257	RBBP6	100	98.667	ENSPTIG00000010342	RBBP6	94	94.444	Panthera_tigris_altaica
ENSG00000122257	RBBP6	100	100.000	ENSPTRG00000007897	RBBP6	100	99.769	Pan_troglodytes
ENSG00000122257	RBBP6	100	99.667	ENSPANG00000019625	RBBP6	100	99.306	Papio_anubis
ENSG00000122257	RBBP6	97	97.015	ENSPSIG00000004108	RBBP6	92	72.000	Pelodiscus_sinensis
ENSG00000122257	RBBP6	100	97.468	ENSPCIG00000014000	RBBP6	94	84.247	Phascolarctos_cinereus
ENSG00000122257	RBBP6	100	100.000	ENSPPYG00000007201	RBBP6	100	98.976	Pongo_abelii
ENSG00000122257	RBBP6	100	99.333	ENSPCOG00000021939	RBBP6	100	98.380	Propithecus_coquereli
ENSG00000122257	RBBP6	97	100.000	ENSPVAG00000001110	RBBP6	83	90.520	Pteropus_vampyrus
ENSG00000122257	RBBP6	100	98.339	ENSRNOG00000012806	Rbbp6	94	88.614	Rattus_norvegicus
ENSG00000122257	RBBP6	100	100.000	ENSRBIG00000004517	RBBP6	100	95.594	Rhinopithecus_bieti
ENSG00000122257	RBBP6	100	100.000	ENSRROG00000032092	RBBP6	100	99.537	Rhinopithecus_roxellana
ENSG00000122257	RBBP6	100	99.008	ENSSBOG00000021666	RBBP6	100	97.546	Saimiri_boliviensis_boliviensis
ENSG00000122257	RBBP6	99	92.647	ENSSHAG00000002006	-	93	94.595	Sarcophilus_harrisii
ENSG00000122257	RBBP6	100	98.333	ENSSHAG00000004727	-	100	85.047	Sarcophilus_harrisii
ENSG00000122257	RBBP6	100	84.000	ENSSFOG00015014316	RBBP6	83	65.703	Scleropages_formosus
ENSG00000122257	RBBP6	97	98.507	ENSSARG00000004977	RBBP6	100	89.480	Sorex_araneus
ENSG00000122257	RBBP6	97	97.015	ENSSPUG00000010682	RBBP6	89	82.493	Sphenodon_punctatus
ENSG00000122257	RBBP6	100	98.667	ENSSSCG00000007830	RBBP6	100	93.370	Sus_scrofa
ENSG00000122257	RBBP6	97	97.761	ENSTGUG00000006185	RBBP6	95	70.024	Taeniopygia_guttata
ENSG00000122257	RBBP6	97	99.254	ENSTTRG00000002696	RBBP6	94	92.335	Tursiops_truncatus
ENSG00000122257	RBBP6	99	98.529	ENSUAMG00000006649	-	94	96.413	Ursus_americanus
ENSG00000122257	RBBP6	97	100.000	ENSUMAG00000008537	RBBP6	98	92.955	Ursus_maritimus
ENSG00000122257	RBBP6	97	100.000	ENSVPAG00000006458	RBBP6	79	94.013	Vicugna_pacos
ENSG00000122257	RBBP6	100	98.667	ENSVVUG00000005484	RBBP6	98	94.432	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000209	protein polyubiquitination	-	TAS	Process
GO:0001701	in utero embryonic development	-	IEA	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0004842	ubiquitin-protein transferase activity	18851979.	IDA	Function
GO:0005515	protein binding	18624398.18851979.24726359.	IPI	Function
GO:0005694	chromosome	-	IEA	Component
GO:0005730	nucleolus	-	IEA	Component
GO:0005813	centrosome	20873783.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006260	DNA replication	-	IEA	Process
GO:0006275	regulation of DNA replication	24726359.	IMP	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0006511	ubiquitin-dependent protein catabolic process	18851979.	IDA	Process
GO:0006511	ubiquitin-dependent protein catabolic process	24726359.	IMP	Process
GO:0006974	cellular response to DNA damage stimulus	24726359.	IMP	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0016607	nuclear speck	-	IDA	Component
GO:0019901	protein kinase binding	20873783.	IPI	Function
GO:0032991	protein-containing complex	20873783.	IDA	Component
GO:0035264	multicellular organism growth	-	IEA	Process
GO:0048568	embryonic organ development	-	IEA	Process
GO:0061053	somite development	-	IEA	Process
GO:0061630	ubiquitin protein ligase activity	24726359.	IMP	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.