EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21175803	Aberrant expression and localization of hnRNP-A2/B1 is a common event in human gastric adenocarcinoma.	J Gastroenterol Hepatol	2011 Jan	Jing GJ	doi: 10.1111/j.1440-1746.2010.06482.x.
15703215	The microtubule-associated protein tumor overexpressed gene binds to the RNA trafficking protein heterogeneous nuclear ribonucleoprotein A2.	Mol Biol Cell	2005 Apr	Kosturko LD	-
21321999	The localization of hnRNP A2/B1 in nuclear matrix and the aberrant expression during the RA-induced differentiation of human neuroblastoma SK-N-SH cells.	J Cell Biochem	2011 Jul	Liang Y	doi: 10.1002/jcb.23063.
12065097	Increased expression of heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP) in pancreatic tissue from smokers and pancreatic tumor cells.	Cancer Lett	2002 Sep 26	Yan-Sanders Y	-
21547579	VHL genetic alteration in CCRCC does not determine de-regulation of HIF, CAIX, hnRNP A2/B1 and osteopontin.	Cell Oncol (Dordr)	2011 Jun	Nyhan MJ	doi: 10.1007/s13402-011-0029-5
26774881	hnRNPA2/B1 activates cyclooxygenase-2 and promotes tumor growth in human lung cancers.	Mol Oncol	2016 Apr	Xuan Y	doi: 10.1016/j.molonc.2015.11.010
24823909	The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer.	RNA Biol	2014	Stockley J	-
28831131	Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression.	Sci Rep	2017 Aug 22	Hung CY	doi: 10.1038/s41598-017-09558-7.
18461365	Establishment of a new method, transcription-reverse transcription concerted reaction, for detection of plasma hnRNP B1 mRNA, a biomarker of lung cancer.	J Cancer Res Clin Oncol	2008 Nov	Sato A	doi: 10.1007/s00432-008-0402-6
15147968	Post-transcriptional regulation of glucose transporter-1 by an AU-rich element in the 3'UTR and by hnRNP A2.	Biochem Biophys Res Commun	2004 Jun 11	Griffin ME	-
26805816	Unraveling Molecular Differences of Gastric Cancer by Label-Free Quantitative Proteomics Analysis.	Int J Mol Sci	2016 Jan 21	Dai P	doi: 10.3390/ijms17010069.
17067748	Prognostic and diagnostic relevance of hnRNP A2/B1, hnRNP B1 and S100 A2 in non-small cell lung cancer.	Cancer Detect Prev	2006	Zech VF	-
21642356	Fyn requires HnRNPA2B1 and Sam68 to synergistically regulate apoptosis in pancreatic cancer.	Carcinogenesis	2011 Oct	Chen ZY	doi: 10.1093/carcin/bgr088
23658645	HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells.	PLoS One	2013 Apr 29	Guo R	doi: 10.1371/journal.pone.0062729
22325225	[Expression of EGFR, survivn and hnRNPA2/B1 in bronchial brushing cytology specimens and their significance in diagnosis of lung cancer].	Zhonghua Zhong Liu Za Zhi	2011 Aug	Lu SS	-
28351333	Splicing factor hnRNPA2B1 contributes to tumorigenic potential of breast cancer cells through STAT3 and ERK1/2 signaling pathway.	Tumour Biol	2017 Mar	Hu Y	doi: 10.1177/1010428317694318.
27989750	The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition.	Free Radic Biol Med	2016 Dec	Brandi J	doi: 10.1016/j.freeradbiomed.2016.10.499
29328485	Knockdown of hnRNP A2/B1 inhibits cell proliferation, invasion and cell cycle triggering apoptosis in cervical cancer via PI3K/AKT signaling pathway.	Oncol Rep	2018 Mar	Shi X	doi: 10.3892/or.2018.6195

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr7	26197356	Missense_Mutation	novel	D87H	0.28
BLCA	chr7	26196438	Silent	rs75052951	F219F	0.25
BLCA	chr7	26197661	Silent	NA	R38R	0.23
BLCA	chr7	26192529	Missense_Mutation	novel	R350K	0.36
BLCA	chr7	26200695	5'UTR	novel		0.49
BLCA	chr7	26197675	Missense_Mutation	novel	E34K	0.11
BLCA	chr7	26200729	5'UTR	novel		0.3
BLCA	chr7	26196889	Missense_Mutation	NA	I143M	0.52	RRM_1
BLCA	chr7	26200708	5'UTR	novel		0.29
BLCA	chr7	26197389	Missense_Mutation	novel	D76H	0.32
BLCA	chr7	26200719	5'UTR	novel		0.39
BLCA	chr7	26192528	Silent	novel	R350R	0.25
BLCA	chr7	26196921	Missense_Mutation	NA	E133Q	0.29	RRM_1
BLCA	chr7	26196570	Missense_Mutation	novel	R200S	0.24
BLCA	chr7	26197729	Missense_Mutation	novel	E16Q	0.28
BLCA	chr7	26200578	5'UTR	novel		0.37
BLCA	chr7	26197684	Missense_Mutation	NA	E31Q	0.21
BLCA	chr7	26197675	Missense_Mutation	novel	E34K	0.19
BRCA	chr7	26193683	Nonsense_Mutation	NA	G257*	0.2
BRCA	chr7	26197350	Frame_Shift_Del	novel	*P83Efs2**	0.31
BRCA	chr7	26197651	Missense_Mutation	NA	E42Q	0.16
BRCA	chr7	26196991	Silent	novel	V109V	0.24
BRCA	chr7	26193583	Missense_Mutation	NA	Y290C	0.44
BRCA	chr7	26193300	Missense_Mutation	NA	K317N	0.33
BRCA	chr7	26197406	Missense_Mutation	novel	S70L	0.19
BRCA	chr7	26200676	5'UTR	novel		0.27
BRCA	chr7	26197729	Missense_Mutation	NA	E16K	0.19
CESC	chr7	26192121	3'UTR	novel		0.26
CESC	chr7	26197664	Silent	novel	L37L	0.28
CESC	chr7	26191058	3'UTR	NA		0.33
CESC	chr7	26196450	Silent	rs780448110	G215G	0.27
CESC	chr7	26190219	3'UTR	novel		0.14
CHOL	chr7	26197701	Missense_Mutation	novel	I25T	0.63
COAD	chr7	26193368	Splice_Site	NA	X293_splice	0.42
COAD	chr7	26197430	Missense_Mutation	NA	R62I	0.37
COAD	chr7	26193312	In_Frame_Del	NA	Y313del	0.27
COAD	chr7	26196591	Missense_Mutation	NA	M193I	0.35
COAD	chr7	26196605	Missense_Mutation	NA	S189P	0.35
COAD	chr7	26193375	Splice_Site	NA	X293_splice	0.15
COAD	chr7	26196429	Silent	novel	G222G	0.08
ESCA	chr7	26192139	3'UTR	novel		0.1
ESCA	chr7	26192054	3'UTR	novel		0.23
ESCA	chr7	26192156	3'UTR	novel		0.29
ESCA	chr7	26200794	5'Flank	novel		0.54
ESCA	chr7	26200729	5'UTR	novel		0.19
ESCA	chr7	26193611	Missense_Mutation	novel	G281R	0.08
ESCA	chr7	26200711	5'UTR	NA		0.26
GBM	chr7	26196610	Missense_Mutation	NA	A187V	0.2
HNSC	chr7	26200676	5'UTR	novel		0.27
HNSC	chr7	26196828	Missense_Mutation	novel	D164N	0.11	RRM_1
HNSC	chr7	26193259	Missense_Mutation	rs770089393	Y331C	0.37
HNSC	chr7	26193671	Missense_Mutation	rs375157988	G261S	0.26
HNSC	chr7	26193264	Frame_Shift_Ins	novel	*P330Tfs37**	0.22
HNSC	chr7	26196601	Missense_Mutation	novel	R190T	0.28
HNSC	chr7	26196459	Silent	novel	S212S	0.19
HNSC	chr7	26200749	5'Flank	novel		0.25
KICH	chr7	26200609	5'UTR	novel		0.15
KIRC	chr7	26195892	Missense_Mutation	NA	R238S	0.19
KIRP	chr7	26200716	5'UTR	novel		0.74
KIRP	chr7	26195854	Silent	novel	G250G	0.46
KIRP	chr7	26195889	Missense_Mutation	NA	G239R	0.45
LIHC	chr7	26196828	Missense_Mutation	novel	D164Y	0.46	RRM_1
LIHC	chr7	26197645	Missense_Mutation	NA	W44G	0.25
LIHC	chr7	26200714	5'UTR	novel		0.54
LIHC	chr7	26193288	Silent	rs774142726	F321F	0.32
LIHC	chr7	26193318	In_Frame_Del	novel	S311del	0.37
LUAD	chr7	26193257	Missense_Mutation	novel	G332C	0.11
LUAD	chr7	26197456	Missense_Mutation	NA	M53I	0.08
LUAD	chr7	26197356	Missense_Mutation	novel	D87H	0.09
LUAD	chr7	26193689	Missense_Mutation	NA	N255Y	0.4
LUAD	chr7	26200767	5'Flank	novel		0.44
LUAD	chr7	26197395	Nonsense_Mutation	novel	E74*	0.06
LUAD	chr7	26196445	Missense_Mutation	novel	G217V	0.33
LUAD	chr7	26192571	Missense_Mutation	novel	Y336C	0.25
LUAD	chr7	26195906	Missense_Mutation	NA	G233A	0.16
LUAD	chr7	26200571	Splice_Site	novel	X2_splice	0.14
LUSC	chr7	26195894	Missense_Mutation	NA	G237V	0.38
LUSC	chr7	26200774	5'Flank	novel		0.33
LUSC	chr7	26195862	Nonsense_Mutation	novel	G248*	0.07
LUSC	chr7	26200725	5'UTR	rs566739502		0.15
LUSC	chr7	26197341	Missense_Mutation	NA	E92Q	0.12
LUSC	chr7	26197341	Missense_Mutation	NA	E92Q	0.17
OV	chr7	26193606	Silent	NA	G282G	0.9
READ	chr7	26192276	3'UTR	rs548602926		0.45
SARC	chr7	26190471	3'UTR	novel		0.44
SKCM	chr7	26197641	Missense_Mutation	novel	G45V	0.31
SKCM	chr7	26197310	Splice_Site	novel	X100_splice	0.35
SKCM	chr7	26192567	Silent	NA	G337G	0.37
SKCM	chr7	26192553	Missense_Mutation	novel	G342E	0.66
SKCM	chr7	26192554	Missense_Mutation	novel	G342R	0.66
SKCM	chr7	26196596	Missense_Mutation	NA	E192K	0.63
SKCM	chr7	26193659	Missense_Mutation	NA	G265R	0.37
SKCM	chr7	26192554	Missense_Mutation	novel	G342R	0.32
SKCM	chr7	26193340	Missense_Mutation	NA	G304E	0.24
SKCM	chr7	26200639	5'UTR	novel		0.26
SKCM	chr7	26197016	Missense_Mutation	novel	E101G	0.5
SKCM	chr7	26196878	Missense_Mutation	NA	R147K	0.27	RRM_1
STAD	chr7	26193677	Missense_Mutation	NA	S259C	0.23
STAD	chr7	26193264	Frame_Shift_Ins	novel	*P330Tfs37**	0.1
STAD	chr7	26193696	Splice_Site	NA	X253_splice	0.23
STAD	chr7	26195892	Missense_Mutation	NA	R238C	0.23
STAD	chr7	26196905	Frame_Shift_Ins	novel	*I138Nfs2**	0.13	RRM_1
STAD	chr7	26192524	Nonsense_Mutation	novel	R352*	0.26
STAD	chr7	26197338	Missense_Mutation	NA	P93S	0.21
STAD	chr7	26196814	In_Frame_Ins	novel	D167_K168insN	0.28	RRM_1
THYM	chr7	26200708	5'UTR	novel		0.08
UCEC	chr7	26193610	Missense_Mutation	novel	G281V	0.15
UCEC	chr7	26200741	5'UTR	novel		0.38
UCEC	chr7	26193374	Splice_Site	NA	X293_splice	0.42
UCEC	chr7	26191210	3'UTR	novel		0.53
UCEC	chr7	26192338	Splice_Region	novel		0.21
UCEC	chr7	26190366	3'UTR	novel		0.22
UCEC	chr7	26197327	Silent	novel	A96A	0.35
UCEC	chr7	26196806	Splice_Site	novel	X171_splice	0.05
UCEC	chr7	26196929	Missense_Mutation	novel	D130A	0.19	RRM_1
UCEC	chr7	26197722	Missense_Mutation	novel	E18G	0.18
UCEC	chr7	26196904	Silent	novel	I138I	0.41
UCEC	chr7	26193603	Silent	NA	Y283Y	0.47
UCEC	chr7	26200678	5'UTR	novel		0.38
UCEC	chr7	26197620	Splice_Site	novel	X51_splice	0.45
UCEC	chr7	26190485	3'UTR	novel		0.3
UCEC	chr7	26190918	3'UTR	novel		0.38
UCEC	chr7	26193375	Splice_Site	NA	X293_splice	0.51
UCEC	chr7	26191853	3'UTR	novel		0.26
UCEC	chr7	26191055	3'UTR	novel		0.47
UCEC	chr7	26191931	3'UTR	novel		0.33
UCEC	chr7	26193269	Missense_Mutation	NA	G328W	0.07
UCEC	chr7	26191911	3'UTR	novel		0.63
UCEC	chr7	26192121	3'UTR	novel		0.39
UCEC	chr7	26195892	Missense_Mutation	NA	R238C	0.32
UCEC	chr7	26192518	Nonstop_Mutation	novel	354Rext13	0.37
UCEC	chr7	26191033	3'UTR	novel		0.4
UCEC	chr7	26192277	3'UTR	novel		0.38
UCEC	chr7	26191913	3'UTR	novel		0.47
UCEC	chr7	26190038	3'UTR	novel		0.36
UCEC	chr7	26192121	3'UTR	novel		0.33
UCEC	chr7	26197682	Missense_Mutation	novel	E31D	0.45
UCEC	chr7	26192121	3'UTR	novel		0.52
UCEC	chr7	26200722	5'UTR	novel		0.34
UCEC	chr7	26192121	3'UTR	novel		0.41
UCEC	chr7	26193375	Splice_Site	novel	X293_splice	0.43
UCEC	chr7	26196951	Missense_Mutation	novel	T123A	0.21	RRM_1
UCEC	chr7	26197460	Missense_Mutation	novel	V52A	0.3
UCEC	chr7	26200784	5'Flank	NA		0.34
UCEC	chr7	26192202	3'UTR	novel		0.29
UCEC	chr7	26190286	3'UTR	novel		0.47
UCEC	chr7	26192121	3'UTR	novel		0.54
UCEC	chr7	26197689	Missense_Mutation	NA	S29N	0.11
UCEC	chr7	26193265	Frame_Shift_Del	NA	*G329Dfs42**	0.44
UCEC	chr7	26190168	3'UTR	novel		0.38
UCS	chr7	26195873	Missense_Mutation	rs775496049	Y244C	0.72

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LUAD	AMP	0.4419	0.17291
PRAD	AMP	0.1402	0.02772
THCA	DEL	0	0.27619

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0035	Kaplan-Meier Survival Analysis
KIRC	0.00019	Kaplan-Meier Survival Analysis
STAD	0.0096	Kaplan-Meier Survival Analysis
SARC	0.0018	Kaplan-Meier Survival Analysis
MESO	0.017	Kaplan-Meier Survival Analysis
ACC	0.0002	Kaplan-Meier Survival Analysis
PRAD	0.0069	Kaplan-Meier Survival Analysis
ESCA	0.013	Kaplan-Meier Survival Analysis
BLCA	0.043	Kaplan-Meier Survival Analysis
LAML	0.039	Kaplan-Meier Survival Analysis
KICH	0.0067	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.00026	Kaplan-Meier Survival Analysis
UVM	0.023	Kaplan-Meier Survival Analysis
OV	0.004	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000122566 (Gene tree)
Gene ID: 3181
Gene Symbol: HNRNPA2B1
Alias: HNRPA2B1
Full Name: heterogeneous nuclear ribonucleoprotein A2/B1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 28,473 bases
Position: chr7:26,173,057-26,201,529
Accession: 5033
RBP type: canonical RBP
Summary: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000478691	RRM_1	PF00076.22	4.6e-32	1	2
ENSP00000478691	RRM_1	PF00076.22	4.6e-32	2	2
ENSP00000349101	RRM_1	PF00076.22	1e-31	1	2
ENSP00000349101	RRM_1	PF00076.22	1e-31	2	2
ENSP00000497298	RRM_1	PF00076.22	1e-31	1	2
ENSP00000497298	RRM_1	PF00076.22	1e-31	2	2
ENSP00000346694	RRM_1	PF00076.22	1.2e-31	1	2
ENSP00000346694	RRM_1	PF00076.22	1.2e-31	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28980860	behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.	Autophagy	2017	Uversky VN	doi: 10.1080/15548627.2017.1384889
29916022	Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD.	Adv Neurobiol	2018	Shenouda M	doi: 10.1007/978-3-319-89689-2_9.
29684050	Intronic PAH gene mutations cause a splicing defect by a novel mechanism involving U1snRNP binding downstream of the 5' splice site.	PLoS Genet	2018 Apr 23	Martinez-Pizarro A	doi: 10.1371/journal.pgen.1007360
11222913	Characterization of hnRNP A2 and B1 using monoclonal antibodies: intracellular distribution and metabolism through cell cycle.	Immunol Lett	2001 Feb 1	Kamma H	-
28993733	LncRNA-uc002mbe.2 Interacting with hnRNPA2B1 Mediates AKT Deactivation and p21 Up-Regulation Induced by Trichostatin in Liver Cancer Cells.	Front Pharmacol	2017 Sep 25	Chen T	doi: 10.3389/fphar.2017.00669
31272829	Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.	Neuron	2019 Jun 18	Fang MY	doi: 10.1016/j.neuron.2019.05.048
16170352	Heterogeneous nuclear ribonucleoprotein A2 is a SET-binding protein and a PP2A inhibitor.	Oncogene	2006 Jan 12	Vera J	-
10197602	Heterogeneous nuclear ribonucleoprotein B1 as a new marker of early detection for human lung cancers.	Cancer Res	1999 Apr 1	Sueoka E	-
20421594	Histochemical mapping of hnRNP A2/B1 in rat brain after ischemia-reperfusion insults.	J Histochem Cytochem	2010 Aug	Liu Y	doi: 10.1369/jhc.2010.955021
25375143	Analysis of nuclear export sequence regions of FUS-Related RNA-binding proteins in essential tremor.	PLoS One	2014 Nov 6	Lorenzo-Betancor O	doi: 10.1371/journal.pone.0111989
26744327	Genetic interaction of hnRNPA2B1 and DNAJB6 in a Drosophila model of multisystem proteinopathy.	Hum Mol Genet	2016 Mar 1	Li S	doi: 10.1093/hmg/ddv627
24823909	The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer.	RNA Biol	2014	Stockley J	-
23938467	Linking spermatid ribonucleic acid (RNA) binding protein and retrogene diversity to reproductive success.	Mol Cell Proteomics	2013 Nov	Chapman KM	doi: 10.1074/mcp.M113.030585
23495120	Heterogeneous nuclear ribonucleoprotein A2/B1 regulates the self-renewal and pluripotency of human embryonic stem cells via the control of the G1/S transition.	Stem Cells	2013 Dec	Choi HS	doi: 10.1002/stem.1366.
28343865	Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.	Neuron	2017 Apr 5	Ishiguro T	doi: 10.1016/j.neuron.2017.02.046
26321680	HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events.	Cell	2015 Sep 10	Alarcon CR	doi: 10.1016/j.cell.2015.08.011
26728149	Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.	Acta Neuropathol	2016 Apr	Daigle JG	doi: 10.1007/s00401-015-1530-0
26362252	Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D.	Hum Mol Genet	2015 Dec 1	Bengoechea R	doi: 10.1093/hmg/ddv363
29203801	De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies.	Sci Rep	2017 Dec 4	Mitsuhashi K	doi: 10.1038/s41598-017-17209-0.
29344170	Phosphorylation of Ser6 in hnRNPA1 by S6K2 regulates glucose metabolism and cell growth in colorectal cancer.	Oncol Lett	2017 Dec	Sun Y	doi: 10.3892/ol.2017.7085
29405028	Next Generation Sequencing and ALS: known genes, different phenotyphes.	Arch Ital Biol	2017 Dec 1	Campopiano R	doi: 10.12871/00039829201742.
30157547	RNA-Binding Proteins in Amyotrophic Lateral Sclerosis.	Mol Cells	2018 Sep 30	Zhao M	doi: 10.14348/molcells.2018.0243
30397184	The SH3 domain of Fyn kinase interacts with and induces liquid-liquid phase separation of the low-complexity domain of hnRNPA2.	J Biol Chem	2018 Dec 21	Amaya J	doi: 10.1074/jbc.RA118.005120
30660504	Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors.	Trends Cell Biol	2019 Apr	Guo L	doi: 10.1016/j.tcb.2018.12.004
31235510	Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli.	J Exp Med	2019 Jun 24	Lee H	doi: 10.1084/jem.20182313
25124043	Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia.	J Biol Chem	2014 Sep 26	Kasim M	doi: 10.1074/jbc.M114.579391
26663205	A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism.	Hepatology	2016 Jul	Lan X	doi: 10.1002/hep.28391

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000354667	HNRNPA2B1-201	3664	XM_005249729	ENSP00000346694	353 (aa)	XP_005249786	P22626
ENST00000618183	HNRNPA2B1-209	3539	-	ENSP00000478691	261 (aa)	-	A0A087WUI2
ENST00000463181	HNRNPA2B1-204	6284	-	-	- (aa)	-	-
ENST00000490912	HNRNPA2B1-206	5328	-	-	- (aa)	-	-
ENST00000476233	HNRNPA2B1-205	1220	-	-	- (aa)	-	-
ENST00000356674	HNRNPA2B1-202	1711	XM_017012109	ENSP00000349101	341 (aa)	XP_016867598	P22626
ENST00000360787	HNRNPA2B1-203	1724	-	ENSP00000354021	353 (aa)	-	P22626
ENST00000495810	HNRNPA2B1-207	482	-	-	- (aa)	-	-
ENST00000608362	HNRNPA2B1-208	3497	-	ENSP00000497298	341 (aa)	-	UPI000002B298

Gene Model

Click here to download ENSG00000122566's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000122566's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000122566	HNRNPA2B1	77	32.886	ENSG00000120948	TARDBP	91	30.208
ENSG00000122566	HNRNPA2B1	76	41.176	ENSG00000138668	HNRNPD	100	42.735
ENSG00000122566	HNRNPA2B1	61	33.696	ENSG00000090621	PABPC4	69	32.990
ENSG00000122566	HNRNPA2B1	72	40.828	ENSG00000071626	DAZAP1	54	40.000
ENSG00000122566	HNRNPA2B1	79	46.053	ENSG00000099622	CIRBP	91	47.887
ENSG00000122566	HNRNPA2B1	62	37.500	ENSG00000174740	PABPC5	78	34.524
ENSG00000122566	HNRNPA2B1	76	79.444	ENSG00000170144	HNRNPA3	53	79.444
ENSG00000122566	HNRNPA2B1	67	43.750	ENSG00000135097	MSI1	54	43.750
ENSG00000122566	HNRNPA2B1	62	33.333	ENSG00000101489	CELF4	50	39.344
ENSG00000122566	HNRNPA2B1	69	37.569	ENSG00000197451	HNRNPAB	65	37.895
ENSG00000122566	HNRNPA2B1	72	37.113	ENSG00000132819	RBM38	82	37.113
ENSG00000122566	HNRNPA2B1	68	55.618	ENSG00000177733	HNRNPA0	64	54.082
ENSG00000122566	HNRNPA2B1	84	80.447	ENSG00000135486	HNRNPA1	99	80.357
ENSG00000122566	HNRNPA2B1	84	78.212	ENSG00000139675	HNRNPA1L2	63	75.385
ENSG00000122566	HNRNPA2B1	84	37.963	ENSG00000153944	MSI2	77	50.000
ENSG00000122566	HNRNPA2B1	58	40.816	ENSG00000131051	RBM39	64	40.816
ENSG00000122566	HNRNPA2B1	51	44.776	ENSG00000147274	RBMX	83	47.541
ENSG00000122566	HNRNPA2B1	73	38.824	ENSG00000152795	HNRNPDL	62	38.542
ENSG00000122566	HNRNPA2B1	71	32.911	ENSG00000140488	CELF6	63	33.333
ENSG00000122566	HNRNPA2B1	55	41.791	ENSG00000213516	RBMXL1	53	37.349
ENSG00000122566	HNRNPA2B1	55	44.898	ENSG00000100461	RBM23	50	44.898

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000122566	HNRNPA2B1	99	99.716	ENSAMEG00000005983	HNRNPA2B1	99	99.716	Ailuropoda_melanoleuca
ENSG00000122566	HNRNPA2B1	100	98.240	ENSAPLG00000012019	HNRNPA2B1	99	97.143	Anas_platyrhynchos
ENSG00000122566	HNRNPA2B1	99	94.100	ENSACAG00000012992	HNRNPA2B1	98	93.294	Anolis_carolinensis
ENSG00000122566	HNRNPA2B1	100	98.534	ENSANAG00000020524	-	99	98.817	Aotus_nancymaae
ENSG00000122566	HNRNPA2B1	100	100.000	ENSANAG00000033016	HNRNPA2B1	100	100.000	Aotus_nancymaae
ENSG00000122566	HNRNPA2B1	100	100.000	ENSBTAG00000005726	HNRNPA2B1	100	100.000	Bos_taurus
ENSG00000122566	HNRNPA2B1	95	71.255	ENSBTAG00000054873	-	99	71.255	Bos_taurus
ENSG00000122566	HNRNPA2B1	64	71.591	ENSBTAG00000054428	-	92	70.787	Bos_taurus
ENSG00000122566	HNRNPA2B1	92	79.310	ENSBTAG00000051697	-	73	98.857	Bos_taurus
ENSG00000122566	HNRNPA2B1	63	84.932	ENSBTAG00000053612	-	71	84.932	Bos_taurus
ENSG00000122566	HNRNPA2B1	95	70.245	ENSBTAG00000038680	-	55	76.961	Bos_taurus
ENSG00000122566	HNRNPA2B1	96	68.639	ENSBTAG00000011195	-	64	73.529	Bos_taurus
ENSG00000122566	HNRNPA2B1	93	79.211	ENSCJAG00000047538	-	70	97.368	Callithrix_jacchus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCJAG00000007908	HNRNPA2B1	100	100.000	Callithrix_jacchus
ENSG00000122566	HNRNPA2B1	99	99.716	ENSCAFG00000002885	HNRNPA2B1	100	100.000	Canis_familiaris
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCAFG00020003488	HNRNPA2B1	100	100.000	Canis_lupus_dingo
ENSG00000122566	HNRNPA2B1	95	64.615	ENSCHIG00000011148	-	92	60.486	Capra_hircus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCHIG00000022444	HNRNPA2B1	100	100.000	Capra_hircus
ENSG00000122566	HNRNPA2B1	74	78.351	ENSCHIG00000026095	-	67	75.336	Capra_hircus
ENSG00000122566	HNRNPA2B1	96	70.948	ENSCHIG00000015823	-	66	80.269	Capra_hircus
ENSG00000122566	HNRNPA2B1	95	84.049	ENSCHIG00000011000	-	98	85.549	Capra_hircus
ENSG00000122566	HNRNPA2B1	74	79.381	ENSCHIG00000008431	-	80	80.296	Capra_hircus
ENSG00000122566	HNRNPA2B1	94	69.255	ENSCHIG00000015804	-	64	75.785	Capra_hircus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSTSYG00000008124	HNRNPA2B1	100	100.000	Carlito_syrichta
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCPOG00000036630	HNRNPA2B1	100	100.000	Cavia_porcellus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCCAG00000029074	HNRNPA2B1	100	100.000	Cebus_capucinus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCATG00000033325	HNRNPA2B1	100	100.000	Cercocebus_atys
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCLAG00000014058	HNRNPA2B1	100	100.000	Chinchilla_lanigera
ENSG00000122566	HNRNPA2B1	91	81.905	ENSCLAG00000016182	-	65	92.825	Chinchilla_lanigera
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCSAG00000014175	HNRNPA2B1	100	100.000	Chlorocebus_sabaeus
ENSG00000122566	HNRNPA2B1	93	91.824	ENSCSAG00000005140	-	100	91.824	Chlorocebus_sabaeus
ENSG00000122566	HNRNPA2B1	99	99.705	ENSCHOG00000013832	HNRNPA2B1	100	99.705	Choloepus_hoffmanni
ENSG00000122566	HNRNPA2B1	99	100.000	ENSCPBG00000022485	HNRNPA2B1	98	99.125	Chrysemys_picta_bellii
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCANG00000028734	HNRNPA2B1	100	100.000	Colobus_angolensis_palliatus
ENSG00000122566	HNRNPA2B1	94	64.919	ENSCGRG00001020496	-	94	68.293	Cricetulus_griseus_chok1gshd
ENSG00000122566	HNRNPA2B1	100	100.000	ENSCGRG00001022416	-	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000122566	HNRNPA2B1	99	99.716	ENSCGRG00000015964	-	99	99.716	Cricetulus_griseus_crigri
ENSG00000122566	HNRNPA2B1	94	64.919	ENSCGRG00000010922	-	94	68.293	Cricetulus_griseus_crigri
ENSG00000122566	HNRNPA2B1	99	99.150	ENSDNOG00000012928	-	99	99.150	Dasypus_novemcinctus
ENSG00000122566	HNRNPA2B1	100	99.707	ENSDNOG00000046740	-	93	99.707	Dasypus_novemcinctus
ENSG00000122566	HNRNPA2B1	89	69.508	ENSDNOG00000043784	-	66	71.681	Dasypus_novemcinctus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSDORG00000005482	Hnrnpa2b1	100	100.000	Dipodomys_ordii
ENSG00000122566	HNRNPA2B1	99	87.500	ENSETEG00000018577	HNRNPA2B1	100	87.500	Echinops_telfairi
ENSG00000122566	HNRNPA2B1	100	100.000	ENSEASG00005022108	HNRNPA2B1	54	100.000	Equus_asinus_asinus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSECAG00000000782	HNRNPA2B1	54	100.000	Equus_caballus
ENSG00000122566	HNRNPA2B1	99	87.143	ENSEEUG00000014880	HNRNPA2B1	100	87.143	Erinaceus_europaeus
ENSG00000122566	HNRNPA2B1	95	66.667	ENSFCAG00000036293	-	100	66.667	Felis_catus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSFCAG00000027765	HNRNPA2B1	100	100.000	Felis_catus
ENSG00000122566	HNRNPA2B1	99	98.525	ENSFALG00000009527	HNRNPA2B1	99	98.525	Ficedula_albicollis
ENSG00000122566	HNRNPA2B1	100	100.000	ENSFDAG00000000793	HNRNPA2B1	100	100.000	Fukomys_damarensis
ENSG00000122566	HNRNPA2B1	99	98.820	ENSGALG00000011036	HNRNPA2B1	99	98.820	Gallus_gallus
ENSG00000122566	HNRNPA2B1	99	100.000	ENSGAGG00000006799	HNRNPA2B1	98	99.125	Gopherus_agassizii
ENSG00000122566	HNRNPA2B1	100	100.000	ENSGGOG00000017072	HNRNPA2B1	100	100.000	Gorilla_gorilla
ENSG00000122566	HNRNPA2B1	94	81.191	ENSHGLG00000010704	-	93	80.805	Heterocephalus_glaber_female
ENSG00000122566	HNRNPA2B1	100	100.000	ENSHGLG00000015396	HNRNPA2B1	100	100.000	Heterocephalus_glaber_female
ENSG00000122566	HNRNPA2B1	94	81.191	ENSHGLG00100009903	-	93	80.805	Heterocephalus_glaber_male
ENSG00000122566	HNRNPA2B1	100	100.000	ENSHGLG00100004637	HNRNPA2B1	100	100.000	Heterocephalus_glaber_male
ENSG00000122566	HNRNPA2B1	92	71.975	ENSSTOG00000025552	-	65	73.991	Ictidomys_tridecemlineatus
ENSG00000122566	HNRNPA2B1	98	79.870	ENSSTOG00000024155	-	50	95.105	Ictidomys_tridecemlineatus
ENSG00000122566	HNRNPA2B1	94	85.366	ENSSTOG00000029449	-	97	85.366	Ictidomys_tridecemlineatus
ENSG00000122566	HNRNPA2B1	94	79.688	ENSSTOG00000026412	-	57	84.896	Ictidomys_tridecemlineatus
ENSG00000122566	HNRNPA2B1	100	99.717	ENSSTOG00000006202	-	100	99.717	Ictidomys_tridecemlineatus
ENSG00000122566	HNRNPA2B1	92	81.818	ENSSTOG00000034171	-	100	83.636	Ictidomys_tridecemlineatus
ENSG00000122566	HNRNPA2B1	99	99.716	ENSJJAG00000000278	-	95	99.716	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	99	99.716	ENSJJAG00000000423	-	95	99.716	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	91	85.804	ENSJJAG00000016790	-	94	85.893	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	89	85.246	ENSJJAG00000018972	-	95	84.691	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	91	78.505	ENSJJAG00000023126	-	78	89.076	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	100	78.070	ENSJJAG00000012306	-	74	90.308	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	90	81.013	ENSJJAG00000022256	-	80	92.946	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	98	81.641	ENSJJAG00000013880	-	100	80.469	Jaculus_jaculus
ENSG00000122566	HNRNPA2B1	84	85.047	ENSLACG00000013590	HNRNPA2B1	80	83.190	Latimeria_chalumnae
ENSG00000122566	HNRNPA2B1	100	99.413	ENSLAFG00000006902	HNRNPA2B1	99	99.148	Loxodonta_africana
ENSG00000122566	HNRNPA2B1	100	100.000	ENSMFAG00000002536	HNRNPA2B1	100	100.000	Macaca_fascicularis
ENSG00000122566	HNRNPA2B1	100	100.000	ENSMMUG00000003619	HNRNPA2B1	100	100.000	Macaca_mulatta
ENSG00000122566	HNRNPA2B1	100	100.000	ENSMNEG00000029148	HNRNPA2B1	100	100.000	Macaca_nemestrina
ENSG00000122566	HNRNPA2B1	100	100.000	ENSMLEG00000040848	HNRNPA2B1	100	100.000	Mandrillus_leucophaeus
ENSG00000122566	HNRNPA2B1	99	98.820	ENSMGAG00000010635	HNRNPA2B1	100	98.820	Meleagris_gallopavo
ENSG00000122566	HNRNPA2B1	100	100.000	ENSMAUG00000005706	-	100	100.000	Mesocricetus_auratus
ENSG00000122566	HNRNPA2B1	93	75.000	ENSMAUG00000015003	-	75	92.241	Mesocricetus_auratus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSMICG00000030570	HNRNPA2B1	100	100.000	Microcebus_murinus
ENSG00000122566	HNRNPA2B1	100	82.642	ENSMICG00000002750	-	100	82.642	Microcebus_murinus
ENSG00000122566	HNRNPA2B1	94	77.188	ENSMOCG00000021250	-	72	85.593	Microtus_ochrogaster
ENSG00000122566	HNRNPA2B1	100	100.000	ENSMOCG00000009258	-	100	100.000	Microtus_ochrogaster
ENSG00000122566	HNRNPA2B1	98	99.668	ENSMODG00000000603	HNRNPA2B1	100	99.668	Monodelphis_domestica
ENSG00000122566	HNRNPA2B1	100	100.000	MGP_CAROLIEiJ_G0028377	Hnrnpa2b1	100	100.000	Mus_caroli
ENSG00000122566	HNRNPA2B1	100	99.717	ENSMUSG00000004980	Hnrnpa2b1	100	99.717	Mus_musculus
ENSG00000122566	HNRNPA2B1	100	99.433	MGP_PahariEiJ_G0022127	Hnrnpa2b1	100	99.433	Mus_pahari
ENSG00000122566	HNRNPA2B1	100	99.717	MGP_SPRETEiJ_G0029379	Hnrnpa2b1	100	99.717	Mus_spretus
ENSG00000122566	HNRNPA2B1	99	99.716	ENSMPUG00000004554	HNRNPA2B1	99	99.716	Mustela_putorius_furo
ENSG00000122566	HNRNPA2B1	100	84.884	ENSMPUG00000017012	-	100	88.270	Mustela_putorius_furo
ENSG00000122566	HNRNPA2B1	100	97.654	ENSMLUG00000028687	-	92	97.654	Myotis_lucifugus
ENSG00000122566	HNRNPA2B1	99	97.688	ENSMLUG00000007578	HNRNPA2B1	98	97.688	Myotis_lucifugus
ENSG00000122566	HNRNPA2B1	100	99.433	ENSNGAG00000015156	-	100	99.433	Nannospalax_galili
ENSG00000122566	HNRNPA2B1	95	61.923	ENSNGAG00000000224	-	99	61.686	Nannospalax_galili
ENSG00000122566	HNRNPA2B1	94	73.984	ENSNGAG00000017267	-	82	73.984	Nannospalax_galili
ENSG00000122566	HNRNPA2B1	100	90.616	ENSNGAG00000017486	-	99	89.398	Nannospalax_galili
ENSG00000122566	HNRNPA2B1	100	100.000	ENSNLEG00000014918	HNRNPA2B1	100	100.000	Nomascus_leucogenys
ENSG00000122566	HNRNPA2B1	70	98.745	ENSMEUG00000014479	-	77	98.745	Notamacropus_eugenii
ENSG00000122566	HNRNPA2B1	99	99.705	ENSMEUG00000001084	HNRNPA2B1	100	99.705	Notamacropus_eugenii
ENSG00000122566	HNRNPA2B1	74	70.256	ENSMEUG00000001826	-	52	74.545	Notamacropus_eugenii
ENSG00000122566	HNRNPA2B1	98	99.007	ENSOPRG00000011698	HNRNPA2B1	76	99.007	Ochotona_princeps
ENSG00000122566	HNRNPA2B1	100	96.481	ENSODEG00000018537	-	100	96.481	Octodon_degus
ENSG00000122566	HNRNPA2B1	99	78.682	ENSODEG00000005746	-	96	78.682	Octodon_degus
ENSG00000122566	HNRNPA2B1	92	78.328	ENSODEG00000005464	-	73	79.675	Octodon_degus
ENSG00000122566	HNRNPA2B1	99	74.702	ENSODEG00000009329	-	91	75.719	Octodon_degus
ENSG00000122566	HNRNPA2B1	99	89.941	ENSODEG00000000652	-	93	88.685	Octodon_degus
ENSG00000122566	HNRNPA2B1	100	97.734	ENSODEG00000008757	-	100	97.734	Octodon_degus
ENSG00000122566	HNRNPA2B1	100	98.837	ENSOANG00000009159	HNRNPA2B1	87	98.837	Ornithorhynchus_anatinus
ENSG00000122566	HNRNPA2B1	99	99.148	ENSOCUG00000026859	HNRNPA2B1	99	99.148	Oryctolagus_cuniculus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSOGAG00000015353	HNRNPA2B1	100	100.000	Otolemur_garnettii
ENSG00000122566	HNRNPA2B1	96	65.443	ENSOGAG00000031950	-	58	75.138	Otolemur_garnettii
ENSG00000122566	HNRNPA2B1	74	77.835	ENSOARG00000003965	-	60	76.585	Ovis_aries
ENSG00000122566	HNRNPA2B1	92	88.217	ENSOARG00000005535	-	99	89.349	Ovis_aries
ENSG00000122566	HNRNPA2B1	74	78.866	ENSOARG00000008025	-	74	79.803	Ovis_aries
ENSG00000122566	HNRNPA2B1	95	70.898	ENSOARG00000001157	-	67	76.793	Ovis_aries
ENSG00000122566	HNRNPA2B1	74	64.286	ENSOARG00000013811	-	99	62.605	Ovis_aries
ENSG00000122566	HNRNPA2B1	100	100.000	ENSOARG00000010132	HNRNPA2B1	100	100.000	Ovis_aries
ENSG00000122566	HNRNPA2B1	93	71.609	ENSOARG00000004416	-	66	76.793	Ovis_aries
ENSG00000122566	HNRNPA2B1	74	78.351	ENSOARG00000016439	-	63	77.073	Ovis_aries
ENSG00000122566	HNRNPA2B1	100	100.000	ENSPPAG00000037520	HNRNPA2B1	100	100.000	Pan_paniscus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSPPRG00000019212	HNRNPA2B1	100	100.000	Panthera_pardus
ENSG00000122566	HNRNPA2B1	67	73.864	ENSPTIG00000006805	-	76	75.814	Panthera_tigris_altaica
ENSG00000122566	HNRNPA2B1	100	100.000	ENSPTIG00000019833	HNRNPA2B1	100	100.000	Panthera_tigris_altaica
ENSG00000122566	HNRNPA2B1	100	100.000	ENSPTRG00000019002	HNRNPA2B1	100	100.000	Pan_troglodytes
ENSG00000122566	HNRNPA2B1	100	100.000	ENSPANG00000021598	HNRNPA2B1	100	100.000	Papio_anubis
ENSG00000122566	HNRNPA2B1	99	87.611	ENSPSIG00000002659	HNRNPA2B1	94	91.254	Pelodiscus_sinensis
ENSG00000122566	HNRNPA2B1	100	100.000	ENSPEMG00000014384	Hnrnpa2b1	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000122566	HNRNPA2B1	80	70.556	ENSPMAG00000008270	HNRNPA2B1	78	68.586	Petromyzon_marinus
ENSG00000122566	HNRNPA2B1	99	74.041	ENSPCIG00000013729	HNRNPA2B1	70	78.059	Phascolarctos_cinereus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSPPYG00000017715	HNRNPA2B1	100	100.000	Pongo_abelii
ENSG00000122566	HNRNPA2B1	84	91.284	ENSPCOG00000026324	HNRNPA2B1	86	97.487	Propithecus_coquereli
ENSG00000122566	HNRNPA2B1	99	100.000	ENSPVAG00000006296	HNRNPA2B1	100	100.000	Pteropus_vampyrus
ENSG00000122566	HNRNPA2B1	99	99.716	ENSRNOG00000011175	Hnrnpa2b1	100	99.716	Rattus_norvegicus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSRBIG00000015923	-	100	100.000	Rhinopithecus_bieti
ENSG00000122566	HNRNPA2B1	93	73.780	ENSRBIG00000039719	-	74	86.134	Rhinopithecus_bieti
ENSG00000122566	HNRNPA2B1	100	95.184	ENSRROG00000008368	-	100	95.184	Rhinopithecus_roxellana
ENSG00000122566	HNRNPA2B1	100	100.000	ENSRROG00000020443	-	100	100.000	Rhinopithecus_roxellana
ENSG00000122566	HNRNPA2B1	100	100.000	ENSSBOG00000005245	HNRNPA2B1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000122566	HNRNPA2B1	100	96.481	ENSSHAG00000017930	HNRNPA2B1	96	96.481	Sarcophilus_harrisii
ENSG00000122566	HNRNPA2B1	67	100.000	ENSSARG00000007984	-	52	100.000	Sorex_araneus
ENSG00000122566	HNRNPA2B1	99	98.525	ENSSPUG00000015955	HNRNPA2B1	98	97.668	Sphenodon_punctatus
ENSG00000122566	HNRNPA2B1	96	62.458	ENSSSCG00000013611	-	57	67.725	Sus_scrofa
ENSG00000122566	HNRNPA2B1	100	100.000	ENSSSCG00000036350	HNRNPA2B1	100	100.000	Sus_scrofa
ENSG00000122566	HNRNPA2B1	94	73.668	ENSSSCG00000012503	-	51	80.899	Sus_scrofa
ENSG00000122566	HNRNPA2B1	93	80.122	ENSSSCG00000013607	-	93	78.899	Sus_scrofa
ENSG00000122566	HNRNPA2B1	99	85.251	ENSTGUG00000002869	HNRNPA2B1	63	97.696	Taeniopygia_guttata
ENSG00000122566	HNRNPA2B1	97	84.211	ENSTBEG00000003219	-	99	82.591	Tupaia_belangeri
ENSG00000122566	HNRNPA2B1	100	100.000	ENSTTRG00000000709	HNRNPA2B1	83	100.000	Tursiops_truncatus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSUAMG00000025628	HNRNPA2B1	100	100.000	Ursus_americanus
ENSG00000122566	HNRNPA2B1	100	100.000	ENSUMAG00000001699	HNRNPA2B1	100	100.000	Ursus_maritimus
ENSG00000122566	HNRNPA2B1	99	97.050	ENSVPAG00000010417	HNRNPA2B1	100	97.050	Vicugna_pacos
ENSG00000122566	HNRNPA2B1	100	100.000	ENSVVUG00000000484	HNRNPA2B1	100	100.000	Vulpes_vulpes
ENSG00000122566	HNRNPA2B1	69	93.923	ENSXETG00000012170	hnrnpa2b1	70	85.776	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0000398	mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	9731529.11991638.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	26321680.	IMP	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0000781	chromosome, telomeric region	-	ISS	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003723	RNA binding	15659580.	IDA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	10567417.	IDA	Function
GO:0005515	protein binding	17289661.18519039.21784977.22720776.23976881.24549040.24965446.26321680.26496610.30021884.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	22720776.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005681	spliceosomal complex	9731529.	IDA	Component
GO:0005737	cytoplasm	24356509.	IDA	Component
GO:0006397	mRNA processing	2557628.	IDA	Process
GO:0006406	mRNA export from nucleus	10567417.	IDA	Process
GO:0015030	Cajal body	-	ISS	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016070	RNA metabolic process	-	TAS	Process
GO:0016363	nuclear matrix	-	ISS	Component
GO:0031053	primary miRNA processing	26321680.	IDA	Process
GO:0035198	miRNA binding	24356509.	IDA	Function
GO:0035722	interleukin-12-mediated signaling pathway	-	TAS	Process
GO:0043047	single-stranded telomeric DNA binding	15659580.	IDA	Function
GO:0044806	G-quadruplex DNA unwinding	-	ISS	Process
GO:0048025	negative regulation of mRNA splicing, via spliceosome	-	IEA	Process
GO:0050658	RNA transport	17004321.	IDA	Process
GO:0070062	extracellular exosome	24356509.	IDA	Component
GO:0070062	extracellular exosome	-	TAS	Component
GO:0071013	catalytic step 2 spliceosome	11991638.	IDA	Component
GO:0097157	pre-mRNA intronic binding	-	IEA	Function
GO:0098505	G-rich strand telomeric DNA binding	-	ISS	Function
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	-	ISS	Process
GO:1905663	positive regulation of telomerase RNA reverse transcriptase activity	-	ISS	Process
GO:1990247	N6-methyladenosine-containing RNA binding	26321680.	IDA	Function
GO:1990428	miRNA transport	24356509.	IDA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component
GO:1990904	ribonucleoprotein complex	2557628.17289661.	IDA	Component

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

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Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.