EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21360563	hZIP1 zinc transporter down-regulation in prostate cancer involves the overexpression of ras responsive element binding protein-1 (RREB-1).	Prostate	2011 Oct 1	Zou J	doi: 10.1002/pros.21368
19802870	Ras responsive element binding protein-1 (RREB-1) down-regulates hZIP1 expression in prostate cancer cells.	Prostate	2010 Feb 15	Milon BC	doi: 10.1002/pros.21063.
21703425	RREB1 transcription factor splice variants in urologic cancer.	Am J Pathol	2011 Jul	Nitz MD	doi: 10.1016/j.ajpath.2011.03.038.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr6	7229273	Nonsense_Mutation	NA	Q392*	0.2
BLCA	chr6	7248723	Missense_Mutation	rs767996104	N1607D	0.23
BLCA	chr6	7231243	In_Frame_Del	novel	L1052_L1065del	0.08
BLCA	chr6	7181948	Missense_Mutation	novel	D13H	0.27
BLCA	chr6	7229294	Nonsense_Mutation	NA	Q399*	0.29
BLCA	chr6	7230160	Silent	novel	I687I	0.34
BLCA	chr6	7247142	Missense_Mutation	novel	K1509N	0.12
BLCA	chr6	7182072	Missense_Mutation	NA	R54K	0.62
BLCA	chr6	7231197	Missense_Mutation	novel	S1033L	0.11
BLCA	chr6	7248593	Silent	novel	Q1563Q	0.14
BLCA	chr6	7230169	Silent	NA	L690L	0.32
BLCA	chr6	7229273	Nonsense_Mutation	NA	Q392*	0.19
BLCA	chr6	7231171	Silent	NA	V1024V	0.26
BLCA	chr6	7210822	Silent	NA	E148E	0.28
BLCA	chr6	7231857	Missense_Mutation	novel	R1253L	0.5
BLCA	chr6	7231726	Silent	rs765867404	A1209A	0.33
BLCA	chr6	7229303	Nonsense_Mutation	novel	Q402*	0.32
BLCA	chr6	7229303	Nonsense_Mutation	novel	Q402*	0.13
BLCA	chr6	7230397	Silent	novel	R766R	0.41
BLCA	chr6	7230255	Missense_Mutation	novel	R719H	0.28
BLCA	chr6	7229486	Frame_Shift_Del	novel	*A464Sfs9**	0.79
BRCA	chr6	7189206	Silent	NA	G103G	0.56
BRCA	chr6	7248593	Missense_Mutation	NA	Q1563H	0.17
BRCA	chr6	7229052	Missense_Mutation	novel	C318F	0.13
BRCA	chr6	7248772	Missense_Mutation	novel	A1623G	0.27
BRCA	chr6	7229735	Missense_Mutation	novel	P546S	0.19
BRCA	chr6	7247122	Missense_Mutation	novel	V1503M	0.16
BRCA	chr6	7211603	Missense_Mutation	NA	E201K	0.34
BRCA	chr6	7189256	Missense_Mutation	NA	S120F	0.35
BRCA	chr6	7230187	Missense_Mutation	novel	E696D	0.1
BRCA	chr6	7248538	Missense_Mutation	novel	C1545S	0.09
BRCA	chr6	7182028	Silent	novel	G39G	0.24
BRCA	chr6	7226620	Silent	rs780237679	T287T	0.25
BRCA	chr6	7247108	Missense_Mutation	novel	D1498G	0.3
BRCA	chr6	7211696	Missense_Mutation	NA	D232N	0.19
CESC	chr6	7230857	Silent	novel	L920L	0.27
CESC	chr6	7230862	Missense_Mutation	NA	S921R	0.17
CESC	chr6	7246665	Silent	novel	G1350G	0.45
CESC	chr6	7182019	Missense_Mutation	NA	S36R	0.42
CESC	chr6	7249325	3'UTR	novel		0.36
CESC	chr6	7229519	Silent	NA	L474L	0.27
CESC	chr6	7189256	Missense_Mutation	NA	S120C	0.43
CHOL	chr6	7248925	Missense_Mutation	novel	L1674R	0.5
CHOL	chr6	7189309	Missense_Mutation	NA	G138W	0.5
COAD	chr6	7210871	Missense_Mutation	novel	R165C	0.05
COAD	chr6	7229006	Missense_Mutation	novel	E303K	0.12
COAD	chr6	7246423	Splice_Site	novel	X1270_splice	0.22
COAD	chr6	7240466	Intron	rs758136517		0.45
COAD	chr6	7247047	Missense_Mutation	NA	E1478K	0.35
COAD	chr6	7231623	Missense_Mutation	NA	S1175N	0.18
COAD	chr6	7231683	Missense_Mutation	rs745990582	P1195L	0.32
COAD	chr6	7230982	Missense_Mutation	NA	E961D	0.26
COAD	chr6	7181800	Intron	novel		0.46
COAD	chr6	7187518	Missense_Mutation	novel	R86C	0.21
COAD	chr6	7229024	Missense_Mutation	NA	C309R	0.28
COAD	chr6	7229646	Missense_Mutation	rs751013989	R516Q	0.17
COAD	chr6	7230152	Missense_Mutation	NA	A685T	0.28
COAD	chr6	7230189	Missense_Mutation	NA	R697Q	0.33
DLBC	chr6	7229992	Silent	novel	G631G	0.61
ESCA	chr6	7230047	Nonsense_Mutation	novel	Q650*	0.57
ESCA	chr6	7249962	3'UTR	novel		0.31
ESCA	chr6	7181763	Intron	novel		0.38
ESCA	chr6	7249213	3'UTR	novel		0.13
GBM	chr6	7229626	Silent	novel	P509P	0.09
GBM	chr6	7231698	Missense_Mutation	NA	A1200V	0.18
GBM	chr6	7229018	Missense_Mutation	NA	R307W	0.54
GBM	chr6	7189227	Silent	novel	S110S	0.23
GBM	chr6	7230245	Missense_Mutation	novel	R716W	0.24
GBM	chr6	7230777	Missense_Mutation	rs375275893	A893V	0.21
GBM	chr6	7231032	Missense_Mutation	novel	S978Y	0.26
GBM	chr6	7247086	Missense_Mutation	novel	D1491N	0.27
GBM	chr6	7226552	Missense_Mutation	novel	A265P	0.04
GBM	chr6	7229009	Missense_Mutation	novel	T304A	0.25
GBM	chr6	7226652	Missense_Mutation	novel	S298Y	0.44
GBM	chr6	7230457	Silent	rs750780730	G786G	0.79
HNSC	chr6	7230004	Silent	novel	T635T	0.15
HNSC	chr6	7229130	Missense_Mutation	novel	G344D	0.37
HNSC	chr6	7229536	Silent	rs760414247	S479S	0.11
HNSC	chr6	7230674	Missense_Mutation	novel	L859F	0.42
HNSC	chr6	7231879	Silent	novel	S1260S	0.6
HNSC	chr6	7231880	Silent	NA	L1261L	0.59
HNSC	chr6	7181747	Intron	novel		0.38
HNSC	chr6	7230331	Silent	novel	L744L	0.32
HNSC	chr6	7230988	Silent	novel	A963A	0.76
HNSC	chr6	7229340	Missense_Mutation	novel	P414L	0.33
HNSC	chr6	7210816	Frame_Shift_Del	novel	*E148Sfs11**	0.24
HNSC	chr6	7229903	Missense_Mutation	novel	I602V	0.28	zf-C2H2
HNSC	chr6	7229091	Missense_Mutation	novel	L331R	0.5
KICH	chr6	7231395	Missense_Mutation	rs376220493	T1099M	0.38
KIRC	chr6	7230081	Missense_Mutation	NA	H661R	0.43
KIRC	chr6	7211765	Intron	novel		0.29
KIRC	chr6	7231160	Missense_Mutation	NA	S1021T	0.22
KIRC	chr6	7230129	Missense_Mutation	NA	D677V	0.2
KIRC	chr6	7229147	Missense_Mutation	NA	A350T	0.16
KIRC	chr6	7231033	Silent	NA	S978S	0.41
KIRP	chr6	7248961	Frame_Shift_Del	novel	E1687T	0.38
KIRP	chr6	7189316	Missense_Mutation	novel	M140T	0.29
LAML	chr6	7230358	Silent	NA	T753T	0.33
LAML	chr6	7240595	Intron	novel		0.34
LGG	chr6	7230777	Missense_Mutation	rs375275893	A893V	0.07
LGG	chr6	7181755	Intron	novel		0.21
LGG	chr6	7240473	Intron	NA		0.27
LGG	chr6	7240582	Intron	novel		0.54
LGG	chr6	7230289	Silent	NA	I730I	0.44
LGG	chr6	7231249	Silent	rs146203523	P1050P	0.34
LGG	chr6	7229595	Missense_Mutation	NA	A499V	0.16
LGG	chr6	7231806	Missense_Mutation	rs374868150	R1236Q	0.35
LIHC	chr6	7231302	Missense_Mutation	novel	I1068T	0.74
LIHC	chr6	7181843	Intron	novel		0.3
LIHC	chr6	7231204	Silent	NA	L1035L	0.27
LIHC	chr6	7230175	Silent	novel	T692T	0.48
LUAD	chr6	7231300	Silent	rs756143736	S1067S	0.1
LUAD	chr6	7230748	Silent	NA	S883S	0.18
LUAD	chr6	7248796	Missense_Mutation	novel	H1631R	0.34
LUAD	chr6	7210904	Missense_Mutation	NA	H176D	0.11
LUAD	chr6	7230853	Silent	NA	S918S	0.54
LUAD	chr6	7229259	Missense_Mutation	novel	D387G	0.91
LUAD	chr6	7229994	Missense_Mutation	novel	G632V	0.46
LUAD	chr6	7181899	5'UTR	novel		0.32
LUAD	chr6	7230065	Missense_Mutation	NA	G656R	0.14
LUAD	chr6	7240501	Intron	novel		0.3
LUAD	chr6	7210819	Missense_Mutation	novel	H147Q	0.42
LUAD	chr6	7229950	Missense_Mutation	novel	E617D	0.49
LUAD	chr6	7230499	Silent	novel	A800A	0.18
LUAD	chr6	7231197	Missense_Mutation	novel	S1033L	0.15
LUAD	chr6	7230896	Nonsense_Mutation	novel	E933*	0.31
LUAD	chr6	7229582	Missense_Mutation	NA	A495S	0.05
LUAD	chr6	7231584	Missense_Mutation	rs201015406	R1162L	0.23
LUAD	chr6	7181793	Intron	novel		0.51
LUAD	chr6	7210877	Nonsense_Mutation	novel	R167*	0.06
LUAD	chr6	7229116	Silent	NA	V339V	0.18
LUAD	chr6	7231754	Missense_Mutation	novel	S1219C	0.31
LUAD	chr6	7229906	Nonsense_Mutation	NA	E603*	0.22
LUAD	chr6	7230320	Missense_Mutation	NA	A741P	0.31
LUAD	chr6	7229384	Missense_Mutation	novel	A429S	0.13
LUAD	chr6	7229381	Missense_Mutation	novel	P428A	0.15
LUAD	chr6	7229666	Missense_Mutation	novel	T523S	0.26
LUAD	chr6	7229803	Silent	rs770296374	G568G	0.4
LUAD	chr6	7231021	Silent	NA	A974A	0.3
LUSC	chr6	7247174	Missense_Mutation	novel	R1520Q	0.1
LUSC	chr6	7230758	Missense_Mutation	novel	E887K	0.32
LUSC	chr6	7231234	Silent	novel	L1045L	0.3
LUSC	chr6	7231847	Missense_Mutation	NA	H1250Y	0.39
LUSC	chr6	7248685	Missense_Mutation	novel	N1594S	0.5
LUSC	chr6	7229649	Missense_Mutation	NA	T517M	0.21
LUSC	chr6	7211573	Missense_Mutation	novel	M191V	0.22
LUSC	chr6	7230965	Missense_Mutation	NA	A956S	0.41
LUSC	chr6	7229861	Missense_Mutation	NA	G588C	0.55	zf-C2H2
LUSC	chr6	7231161	Missense_Mutation	NA	S1021L	0.26
LUSC	chr6	7246994	Missense_Mutation	novel	G1460V	0.57
LUSC	chr6	7181860	Intron	novel		0.28
LUSC	chr6	7231588	Silent	rs200032827	P1163P	0.55
LUSC	chr6	7231683	Missense_Mutation	rs745990582	P1195L	0.25
LUSC	chr6	7247210	Missense_Mutation	novel	R1532L	0.32
LUSC	chr6	7247145	Missense_Mutation	NA	R1510S	0.46
LUSC	chr6	7248814	Missense_Mutation	novel	T1637K	0.48
LUSC	chr6	7247121	Silent	rs200867216	S1502S	0.38
LUSC	chr6	7229846	Frame_Shift_Ins	novel	*A584Gfs8**	0.15	zf-C2H2
OV	chr6	7231717	Missense_Mutation	novel	D1206E	0.1
OV	chr6	7226583	Missense_Mutation	NA	P275H	0.25
OV	chr6	7230258	Missense_Mutation	novel	K720R	0.04
OV	chr6	7230259	Frame_Shift_Ins	novel	*K721Rfs20**	0.04
OV	chr6	7230700	Silent	rs769736395	N867N	0.07
OV	chr6	7230957	Frame_Shift_Ins	novel	*S954Vfs10**	0.06
OV	chr6	7230607	Silent	NA	A836A	0.33
OV	chr6	7226493	Missense_Mutation	novel	R245L	0.13
OV	chr6	7181936	Frame_Shift_Del	novel	L9*	0.07
OV	chr6	7211717	Splice_Region	novel		0.1
OV	chr6	7240482	Intron	NA		0.33
OV	chr6	7182064	Silent	NA	R51R	0.15
OV	chr6	7182065	Missense_Mutation	novel	I52V	0.13
OV	chr6	7230444	Missense_Mutation	NA	G782V	0.12
OV	chr6	7226575	Missense_Mutation	novel	Q272H	0.03
OV	chr6	7248519	Missense_Mutation	NA	P1539A	0.22
OV	chr6	7230151	Silent	NA	A684A	0.4
OV	chr6	7240448	Intron	novel		0.16
OV	chr6	7229157	Missense_Mutation	novel	L353P	0.12
OV	chr6	7231039	Silent	NA	P980P	0.28
PAAD	chr6	7229035	Missense_Mutation	novel	E312D	0.05
PAAD	chr6	7229036	Nonsense_Mutation	novel	Q313*	0.06
PAAD	chr6	7230337	Frame_Shift_Del	novel	*D746Efs167**	0.57
PAAD	chr6	7246741	Missense_Mutation	NA	E1376K	0.2
PAAD	chr6	7210877	Nonsense_Mutation	novel	R167*	0.17
PAAD	chr6	7229362	Silent	rs140980354	G421G	0.21
PAAD	chr6	7229646	Missense_Mutation	novel	R516L	0.05
PAAD	chr6	7230174	Missense_Mutation	rs756773469	T692M	0.15
PAAD	chr6	7231793	Silent	novel	L1232L	0.22
PAAD	chr6	7247085	Silent	novel	D1490D	0.21
PAAD	chr6	7230962	Missense_Mutation	rs754945001	E955K	0.16
PAAD	chr6	7226595	Frame_Shift_Ins	novel	*G280Vfs6**	0.05
PAAD	chr6	7229054	Frame_Shift_Ins	novel	*C321Hfs3**	0.15
PAAD	chr6	7231555	In_Frame_Del	novel	G1154_R1160del	0.04
PAAD	chr6	7229237	Missense_Mutation	rs747673605	A380T	0.19
PRAD	chr6	7230378	Missense_Mutation	NA	E760G	0.06
PRAD	chr6	7231174	Frame_Shift_Del	novel	*L1029Efs61**	0.11
PRAD	chr6	7229826	Missense_Mutation	rs745668051	R576Q	0.29
PRAD	chr6	7240457	Intron	novel		0.18
PRAD	chr6	7229070	Missense_Mutation	rs756205550	A324V	0.43
PRAD	chr6	7229845	Silent	novel	P582P	0.43
READ	chr6	7247168	Missense_Mutation	novel	N1518S	0.05
READ	chr6	7231068	Missense_Mutation	NA	E990V	0.13
READ	chr6	7211795	Intron	novel		0.31
READ	chr6	7231309	Missense_Mutation	NA	Q1070H	0.33
SARC	chr6	7247083	Missense_Mutation	rs776759831	D1490N	0.83
SARC	chr6	7230621	Missense_Mutation	rs778172996	A841V	0.41
SKCM	chr6	7210893	Missense_Mutation	NA	R172K	0.17
SKCM	chr6	7229294	Nonsense_Mutation	NA	Q399*	0.69
SKCM	chr6	7229700	Missense_Mutation	NA	S534F	0.29
SKCM	chr6	7229543	Missense_Mutation	NA	P482S	0.81
SKCM	chr6	7231205	Silent	novel	L1036L	0.13
SKCM	chr6	7248587	Silent	rs374502214	I1561I	0.12
SKCM	chr6	7230395	Missense_Mutation	NA	R766C	0.32
SKCM	chr6	7247035	Missense_Mutation	rs201769527	P1474S	0.42
SKCM	chr6	7230132	Missense_Mutation	NA	Y678S	0.11
SKCM	chr6	7230807	Missense_Mutation	NA	S903L	0.28
SKCM	chr6	7230220	Silent	NA	P707P	0.52
SKCM	chr6	7229911	Silent	NA	A604A	0.31
SKCM	chr6	7210859	Missense_Mutation	NA	S161P	0.11
SKCM	chr6	7230616	Silent	rs751045274	A839A	0.21
SKCM	chr6	7231399	Silent	NA	A1100A	0.3
SKCM	chr6	7231642	Silent	NA	I1181I	0.2
SKCM	chr6	7181925	Missense_Mutation	rs745441379	S5L	0.23
SKCM	chr6	7229194	Silent	NA	A365A	0.76
SKCM	chr6	7230892	Silent	rs182302012	S931S	0.29
SKCM	chr6	7229543	Missense_Mutation	NA	P482S	0.2
SKCM	chr6	7229311	Silent	rs142150270	P404P	0.24
SKCM	chr6	7229273	Nonsense_Mutation	NA	Q392*	0.43
SKCM	chr6	7231139	Silent	NA	L1014L	0.27
SKCM	chr6	7247040	Silent	rs531724612	S1475S	0.25
SKCM	chr6	7230853	Silent	NA	S918S	0.34
SKCM	chr6	7230150	Missense_Mutation	NA	A684V	0.3
SKCM	chr6	7230151	Silent	NA	A684A	0.3
SKCM	chr6	7230395	Missense_Mutation	NA	R766C	0.26
SKCM	chr6	7229167	Silent	rs139799223	D356D	0.14
SKCM	chr6	7231669	Silent	NA	T1190T	0.29
SKCM	chr6	7230872	Silent	NA	L925L	0.31
SKCM	chr6	7230916	Silent	NA	I939I	0.16
SKCM	chr6	7231419	Missense_Mutation	rs368515443	S1107F	0.34
SKCM	chr6	7181909	5'UTR	novel		0.14
SKCM	chr6	7240590	Intron	NA		0.47
SKCM	chr6	7230720	Missense_Mutation	rs780527620	P874L	0.61
SKCM	chr6	7229380	Silent	rs200496428	L427L	0.19
SKCM	chr6	7231312	Silent	novel	I1071I	0.08
SKCM	chr6	7210857	Missense_Mutation	NA	P160L	0.34
SKCM	chr6	7230651	Missense_Mutation	rs754554711	A851V	0.4
SKCM	chr6	7231089	Missense_Mutation	rs370598103	P997L	0.35
SKCM	chr6	7230738	Missense_Mutation	NA	P880L	0.05
STAD	chr6	7230369	Missense_Mutation	NA	L757P	0.19
STAD	chr6	7210917	Frame_Shift_Ins	novel	*E181Rfs9**	0.4
STAD	chr6	7189204	Missense_Mutation	rs201588284	G103R	0.15
STAD	chr6	7181917	Silent	rs149124719	T2T	0.17
STAD	chr6	7231844	Frame_Shift_Del	novel	*H1250Tfs36**	0.12
STAD	chr6	7231642	Silent	NA	I1181I	0.17
STAD	chr6	7226522	Missense_Mutation	rs138181401	A255T	0.11
STAD	chr6	7229650	Silent	rs756686713	T517T	0.05
STAD	chr6	7229018	Missense_Mutation	NA	R307W	0.19
STAD	chr6	7229397	Missense_Mutation	novel	S433I	0.43
STAD	chr6	7231590	Missense_Mutation	rs371044808	R1164H	0.38
STAD	chr6	7247082	Silent	novel	S1489S	0.12
STAD	chr6	7229032	Silent	rs751985080	S311S	0.3
STAD	chr6	7229017	Silent	NA	L306L	0.26
STAD	chr6	7248539	Silent	NA	C1545C	0.17
STAD	chr6	7181986	Missense_Mutation	NA	M25I	0.16
STAD	chr6	7240579	Intron	novel		0.2
STAD	chr6	7230152	Missense_Mutation	NA	A685T	0.48
STAD	chr6	7247200	Missense_Mutation	NA	R1529W	0.29
STAD	chr6	7230918	Missense_Mutation	NA	P940L	0.19
STAD	chr6	7231590	Missense_Mutation	rs371044808	R1164H	0.32
STAD	chr6	7246677	Silent	NA	D1354D	0.47
STAD	chr6	7248691	Missense_Mutation	NA	A1596V	0.16
STAD	chr6	7230376	Silent	novel	G759G	0.41
STAD	chr6	7230433	Silent	rs769663945	R778R	0.17
STAD	chr6	7226654	Missense_Mutation	NA	Q299E	0.07
STAD	chr6	7229657	Missense_Mutation	NA	A520T	0.06
STAD	chr6	7231355	Missense_Mutation	rs763437605	V1086M	0.25
STAD	chr6	7211681	Missense_Mutation	NA	M227V	0.27
STAD	chr6	7229165	Missense_Mutation	NA	D356N	0.3
STAD	chr6	7230075	Missense_Mutation	NA	R659H	0.41
STAD	chr6	7210934	Missense_Mutation	NA	A186T	0.06
STAD	chr6	7226524	Silent	rs759101444	A255A	0.16
STAD	chr6	7231739	Missense_Mutation	rs146641651	D1214N	0.22
STAD	chr6	7230255	Missense_Mutation	novel	R719H	0.08
STAD	chr6	7247052	Silent	NA	S1479S	0.24
THCA	chr6	7231705	Silent	NA	D1202D	0.09
THYM	chr6	7210919	Nonsense_Mutation	novel	E181*	0.16
UCEC	chr6	7211584	Silent	rs144915615	D194D	0.49
UCEC	chr6	7230325	Silent	rs756374152	A742A	0.32
UCEC	chr6	7211730	Intron	novel		0.39
UCEC	chr6	7246578	Silent	rs770076990	P1321P	0.44
UCEC	chr6	7181797	Intron	novel		0.48
UCEC	chr6	7247176	Missense_Mutation	novel	F1521L	0.4
UCEC	chr6	7248741	Missense_Mutation	novel	A1613T	0.28
UCEC	chr6	7249115	3'UTR	novel		0.3
UCEC	chr6	7246532	Missense_Mutation	novel	A1306V	0.31
UCEC	chr6	7249799	3'UTR	rs570695709		0.3
UCEC	chr6	7247061	Missense_Mutation	NA	E1482D	0.29
UCEC	chr6	7229120	Missense_Mutation	novel	A341T	0.38
UCEC	chr6	7230057	Missense_Mutation	novel	A653V	0.38
UCEC	chr6	7248679	Missense_Mutation	rs778865424	S1592N	0.48
UCEC	chr6	7246656	Silent	novel	D1347D	0.53
UCEC	chr6	7229033	Missense_Mutation	rs147528961	E312K	0.23
UCEC	chr6	7230278	Missense_Mutation	novel	R727C	0.4
UCEC	chr6	7246679	Missense_Mutation	NA	A1355V	0.48
UCEC	chr6	7248869	Silent	novel	A1655A	0.31
UCEC	chr6	7176746	5'UTR	novel		0.27
UCEC	chr6	7246639	Missense_Mutation	NA	E1342K	0.38
UCEC	chr6	7229384	Missense_Mutation	rs368606725	A429T	0.45
UCEC	chr6	7229070	Missense_Mutation	rs756205550	A324V	0.13
UCEC	chr6	7211828	Intron	novel		0.13
UCEC	chr6	7229121	Missense_Mutation	NA	A341V	0.31
UCEC	chr6	7187493	Silent	novel	T77T	0.45
UCEC	chr6	7230809	Nonsense_Mutation	novel	Q904*	0.48
UCEC	chr6	7246628	Missense_Mutation	novel	E1338A	0.25
UCEC	chr6	7229168	Missense_Mutation	rs370083804	A357T	0.14
UCEC	chr6	7210844	Missense_Mutation	novel	A156S	0.23
UCEC	chr6	7247121	Silent	rs200867216	S1502S	0.25
UCEC	chr6	7248839	Silent	novel	G1645G	0.25
UCEC	chr6	7182063	Missense_Mutation	novel	R51Q	0.16
UCEC	chr6	7247082	Silent	novel	S1489S	0.51
UCEC	chr6	7231590	Missense_Mutation	rs371044808	R1164H	0.38
UCEC	chr6	7229532	Missense_Mutation	rs772060078	A478V	0.35
UCEC	chr6	7229494	Silent	rs138539147	I465I	0.45
UCEC	chr6	7229519	Missense_Mutation	novel	L474M	0.43
UCEC	chr6	7248641	Silent	novel	E1579E	0.5
UCEC	chr6	7229929	Missense_Mutation	novel	M610I	0.39
UCEC	chr6	7231697	Missense_Mutation	novel	A1200T	0.08
UCEC	chr6	7248508	Splice_Region	novel		0.34
UCEC	chr6	7181916	Missense_Mutation	rs755998409	T2M	0.16
UCEC	chr6	7230737	Missense_Mutation	novel	P880T	0.39
UCEC	chr6	7240466	Intron	rs758136517		0.6
UCEC	chr6	7229921	Silent	rs758121441	L608L	0.33
UCEC	chr6	7210871	Missense_Mutation	novel	R165C	0.28
UCEC	chr6	7231679	Missense_Mutation	NA	S1194G	0.54
UCEC	chr6	7230404	Missense_Mutation	NA	R769C	0.29
UCEC	chr6	7246578	Silent	rs770076990	P1321P	0.44
UCEC	chr6	7249357	3'UTR	novel		0.24
UCEC	chr6	7230940	Silent	novel	D947D	0.41
UCEC	chr6	7181976	Missense_Mutation	novel	S22L	0.09
UCEC	chr6	7231642	Silent	NA	I1181I	0.29
UCEC	chr6	7229005	Silent	rs775130340	C302C	0.27
UCEC	chr6	7231624	Silent	rs760574142	S1175S	0.3
UCEC	chr6	7248644	Silent	novel	R1580R	0.28
UCEC	chr6	7246559	Missense_Mutation	rs375377458	T1315M	0.42
UCEC	chr6	7226513	Missense_Mutation	novel	R252C	0.05
UCEC	chr6	7230625	Silent	novel	S842S	0.54
UCEC	chr6	7230082	Silent	rs755607248	H661H	0.2
UCEC	chr6	7230905	Missense_Mutation	rs768531355	D936N	0.42
UCEC	chr6	7249316	3'UTR	novel		0.47
UCEC	chr6	7230240	Missense_Mutation	novel	C714Y	0.69
UCEC	chr6	7230137	Missense_Mutation	NA	A680T	0.57
UCEC	chr6	7181993	Missense_Mutation	novel	G28W	0.46
UCEC	chr6	7182012	Missense_Mutation	novel	G34A	0.41
UCEC	chr6	7226514	Missense_Mutation	rs145465865	R252H	0.06
UCEC	chr6	7229174	Missense_Mutation	novel	D359Y	0.37
UCEC	chr6	7230171	Missense_Mutation	rs115829227	R691H	0.24
UCEC	chr6	7246499	Missense_Mutation	rs748359571	P1295L	0.26
UCEC	chr6	7249281	3'UTR	novel		0.28
UCEC	chr6	7249918	3'UTR	rs531005884		0.09
UCEC	chr6	7226524	Silent	rs759101444	A255A	0.28
UCEC	chr6	7229230	Silent	novel	P377P	0.26
UCEC	chr6	7230817	Silent	NA	G906G	0.32
UCEC	chr6	7229343	Missense_Mutation	novel	F415S	0.61
UCEC	chr6	7230238	Silent	novel	N713N	0.34
UCEC	chr6	7248843	Missense_Mutation	novel	G1647S	0.22
UCEC	chr6	7246897	Missense_Mutation	novel	A1428T	0.6
UCEC	chr6	7249105	3'UTR	novel		0.44
UCEC	chr6	7181929	Silent	rs779379387	P6P	0.42
UCEC	chr6	7230961	Silent	rs147699375	S954S	0.56
UCEC	chr6	7248639	Missense_Mutation	NA	E1579K	0.22
UCEC	chr6	7231436	Missense_Mutation	NA	T1113A	0.25
UCEC	chr6	7248728	Silent	novel	A1608A	0.5
UCEC	chr6	7230003	Missense_Mutation	novel	T635M	0.33
UCEC	chr6	7229446	Silent	novel	Q449Q	0.51
UCEC	chr6	7187438	Missense_Mutation	rs558705748	T59M	0.56
UCEC	chr6	7229494	Silent	rs138539147	I465I	0.45
UCEC	chr6	7248984	3'UTR	novel		0.43
UCEC	chr6	7210906	Silent	rs746694845	H176H	0.52
UCEC	chr6	7231840	Silent	rs745482753	T1247T	0.3
UCS	chr6	7246948	Frame_Shift_Del	novel	*E1447Rfs81**	0.91
UCS	chr6	7240457	Intron	novel		0.08

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1889	0.19267
CESC	DEL	0.1186	0.046699
HNSC	DEL	0.1245	0.0011062
LIHC	AMP	0.3757	1.013e-05
LUSC	DEL	0.2036	0.00029978
PAAD	DEL	0.2989	0.00010152
PRAD	DEL	0.0772	0.059223
SARC	DEL	0.249	0.014376
SKCM	AMP	0.5341	6.548e-09
UVM	AMP	0.55	2.0409e-06

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0015	Kaplan-Meier Survival Analysis
STAD	0.0021	Kaplan-Meier Survival Analysis
MESO	0.032	Kaplan-Meier Survival Analysis
HNSC	0.0075	Kaplan-Meier Survival Analysis
SKCM	0.00099	Kaplan-Meier Survival Analysis
KIRP	0.0023	Kaplan-Meier Survival Analysis
READ	0.035	Kaplan-Meier Survival Analysis
LAML	0.0015	Kaplan-Meier Survival Analysis
GBM	0.04	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
UVM	0.00011	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000124782 (Gene tree)
Gene ID: 6239
Gene Symbol: RREB1
Alias: HNT
Full Name: ras responsive element binding protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 144,384 bases
Position: chr6:7,107,597-7,251,980
Accession: 10449
RBP type: canonical RBP
Summary: The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000369270	zf-C2H2	PF00096.26	5.3e-40	1	4
ENSP00000369270	zf-C2H2	PF00096.26	5.3e-40	2	4
ENSP00000369270	zf-C2H2	PF00096.26	5.3e-40	3	4
ENSP00000369270	zf-C2H2	PF00096.26	5.3e-40	4	4
ENSP00000305560	zf-C2H2	PF00096.26	9.5e-39	1	4
ENSP00000305560	zf-C2H2	PF00096.26	9.5e-39	2	4
ENSP00000305560	zf-C2H2	PF00096.26	9.5e-39	3	4
ENSP00000305560	zf-C2H2	PF00096.26	9.5e-39	4	4
ENSP00000369265	zf-C2H2	PF00096.26	9.5e-39	1	4
ENSP00000369265	zf-C2H2	PF00096.26	9.5e-39	2	4
ENSP00000369265	zf-C2H2	PF00096.26	9.5e-39	3	4
ENSP00000369265	zf-C2H2	PF00096.26	9.5e-39	4	4
ENSP00000335574	zf-C2H2	PF00096.26	7.4e-35	1	5
ENSP00000335574	zf-C2H2	PF00096.26	7.4e-35	2	5
ENSP00000335574	zf-C2H2	PF00096.26	7.4e-35	3	5
ENSP00000335574	zf-C2H2	PF00096.26	7.4e-35	4	5
ENSP00000335574	zf-C2H2	PF00096.26	7.4e-35	5	5
ENSP00000419511	zf-C2H2	PF00096.26	1.4e-27	1	4
ENSP00000419511	zf-C2H2	PF00096.26	1.4e-27	2	4
ENSP00000419511	zf-C2H2	PF00096.26	1.4e-27	3	4
ENSP00000419511	zf-C2H2	PF00096.26	1.4e-27	4	4
ENSP00000483108	zf-C2H2	PF00096.26	3.4e-15	1	4
ENSP00000483108	zf-C2H2	PF00096.26	3.4e-15	2	4
ENSP00000483108	zf-C2H2	PF00096.26	3.4e-15	3	4
ENSP00000483108	zf-C2H2	PF00096.26	3.4e-15	4	4
ENSP00000420299	zf-C2H2	PF00096.26	3.5e-15	1	3
ENSP00000420299	zf-C2H2	PF00096.26	3.5e-15	2	3
ENSP00000420299	zf-C2H2	PF00096.26	3.5e-15	3	3
ENSP00000420519	zf-C2H2	PF00096.26	1.9e-10	1	2
ENSP00000420519	zf-C2H2	PF00096.26	1.9e-10	2	2
ENSP00000305560	zf-met	PF12874.7	8.9e-08	1	1
ENSP00000369265	zf-met	PF12874.7	8.9e-08	1	1
ENSP00000420299	zf-met	PF12874.7	2.9e-07	1	2
ENSP00000420299	zf-met	PF12874.7	2.9e-07	2	2
ENSP00000420519	zf-met	PF12874.7	3.7e-05	1	2
ENSP00000420519	zf-met	PF12874.7	3.7e-05	2	2
ENSP00000369270	zf-met	PF12874.7	0.00017	1	1
ENSP00000483108	zf-met	PF12874.7	0.0007	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28341660	The noncoding RNA linc-ADAMTS5 cooperates with RREB1 to protect from intervertebral disc degeneration through inhibiting ADAMTS5 expression.	Clin Sci (Lond)	2017 May 1	Wang K	doi: 10.1042/CS20160918

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000483150	RREB1-208	2833	-	ENSP00000419511	778 (aa)	-	C9JU34
ENST00000379933	RREB1-203	5826	-	ENSP00000369265	1687 (aa)	-	Q92766
ENST00000379938	RREB1-204	8778	-	ENSP00000369270	1742 (aa)	-	Q92766
ENST00000471433	RREB1-206	1021	-	ENSP00000420299	164 (aa)	-	C9JPJ6
ENST00000334984	RREB1-201	5789	-	ENSP00000335574	1476 (aa)	-	Q92766
ENST00000491191	RREB1-209	998	-	ENSP00000420519	136 (aa)	-	C9JE09
ENST00000611109	RREB1-210	3563	-	ENSP00000483108	755 (aa)	-	A0A087X055
ENST00000475946	RREB1-207	9067	-	-	- (aa)	-	-
ENST00000349384	RREB1-202	7440	-	ENSP00000305560	1687 (aa)	-	Q92766
ENST00000467782	RREB1-205	243	-	ENSP00000420571	4 (aa)	-	UPI0001B793E2

Gene Model

Click here to download ENSG00000124782's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000124782	Parkinson Disease	4.356362E-8	17052657
ENSG00000124782	Social Support	3.1540000E-005	-
ENSG00000124782	Platelet Function Tests	4.5300000E-006	-
ENSG00000124782	Platelet Function Tests	9.9400000E-006	-
ENSG00000124782	Adipose Tissue	1E-8	27918534
ENSG00000124782	Body Mass Index	1E-8	27918534
ENSG00000124782	Waist-Hip Ratio	3E-8	23966867
ENSG00000124782	Multiple System Atrophy	3E-6	27629089
ENSG00000124782	Glucose	3E-7	22581228
ENSG00000124782	Body Mass Index	3E-7	22581228
ENSG00000124782	Adipose Tissue	6E-9	27918534
ENSG00000124782	Body Mass Index	6E-9	27918534
ENSG00000124782	Diabetes Mellitus, Type 2	1E-9	24509480
ENSG00000124782	Optic Disk	2E-8	28073927
ENSG00000124782	Macular Degeneration	1E-6	20385826
ENSG00000124782	Adipose Tissue	2E-6	27918534
ENSG00000124782	Body Mass Index	2E-6	27918534
ENSG00000124782	Adipose Tissue	4E-6	22589738
ENSG00000124782	Body Mass Index	4E-6	22589738
ENSG00000124782	Adipose Tissue	4E-6	22589738
ENSG00000124782	Body Mass Index	4E-6	22589738
ENSG00000124782	Multiple Sclerosis	3E-6	21833088
ENSG00000124782	Body Mass Index	9E-6	27918534
ENSG00000124782	Subcutaneous Fat, Abdominal	9E-6	27918534
ENSG00000124782	Optic Disk	2E-10	28073927

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000124782	rs557074	6	7144958	G	Monocyte count	27863252	[0.022-0.04] unit increase	0.03105644	EFO_0005091
ENSG00000124782	rs55986493	6	7156526	T	Monocyte count	27863252	[0.029-0.057] unit increase	0.04291104	EFO_0005091
ENSG00000124782	rs57996771	6	7157434	C	Reticulocyte count	27863252	[0.023-0.043] unit increase	0.03306844	EFO_0007986
ENSG00000124782	rs75757892	6	7232156	T	Red blood cell count	27863252	[0.023-0.041] unit increase	0.03181995	EFO_0004305
ENSG00000124782	rs11755724	6	7118757	A	Multiple sclerosis	21833088	[1.06-1.09]	1.08	EFO_0003885
ENSG00000124782	rs1413700	6	7216251	G	Multiple system atrophy	27629089		1.39	EFO_1001050
ENSG00000124782	rs11755724	6	7118757	G	Age-related macular degeneration	20385826	[1.09-1.14]	1.15	EFO_0001365
ENSG00000124782	rs6931262	6	7217284	T	Waist-hip ratio	23966867	[0.04-0.08] unit increase	0.06	EFO_0004343
ENSG00000124782	rs2714337	6	7240344	A	Fasting blood glucose	22581228	[0.0071-0.0173] unit decrease	0.0122	EFO_0004465
ENSG00000124782	rs2714337	6	7240344	A	Fasting blood glucose (BMI interaction)	22581228	[-0.00087-0.00141] unit decrease	2.68E-04	EFO_0004340\|EFO_0004465
ENSG00000124782	rs9379084	6	7231610	G	Heel bone mineral density	28869591	[0.024-0.056] unit increase	0.0397905	EFO_0009270
ENSG00000124782	rs9379084	6	7231610	G	Heel bone mineral density	28869591	[0.031-0.052] unit increase	0.0413825	EFO_0009270
ENSG00000124782	rs9379084	6	7231610	G	Heel bone mineral density	28869591	[0.027-0.056] unit increase	0.0410614	EFO_0009270
ENSG00000124782	rs75757892	6	7232156	T	Self-reported math ability (MTAG)	30038396	[0.0087-0.0181] unit increase	0.0134	EFO_0004875
ENSG00000124782	rs147287945	6	7223333	G	Eotaxin levels	27989323	[0.081-0.204] SD units increase	0.1428	EFO_0008122
ENSG00000124782	rs75757892	6	7232156	T	Hematocrit	27863252	[0.025-0.043] unit increase	0.03442745	EFO_0004348
ENSG00000124782	rs1285886	6	7140598	A	Lymphocyte counts	27863252	[0.02-0.038] unit increase	0.02893744	EFO_0004587
ENSG00000124782	rs55986493	6	7156526	T	Myeloid white cell count	27863252	[0.029-0.057] unit increase	0.04286195	EFO_0007988
ENSG00000124782	rs57996771	6	7157434	C	Reticulocyte fraction of red cells	27863252	[0.023-0.043] unit increase	0.03274342	EFO_0007986
ENSG00000124782	rs11303054	6	7138928	C	White blood cell count	27863252	[0.021-0.038] unit increase	0.02959356	EFO_0004308
ENSG00000124782	rs57996771	6	7157434	C	High light scatter reticulocyte count	27863252	[0.02-0.039] unit increase	0.02934395	EFO_0007986
ENSG00000124782	rs4960295	6	7205563	A	Vertical cup-disc ratio	28073927	[0.005-0.009] unit increase	0.007	EFO_0006939
ENSG00000124782	rs4960295	6	7205563	A	Vertical cup-disc ratio	28073927	[0.005-0.009] unit increase	0.007	EFO_0006939
ENSG00000124782	rs1334577	6	7211518	A	Neutrophil count	27863252	[0.017-0.033] unit decrease	0.02485225	EFO_0004833
ENSG00000124782	rs1334577	6	7211518	A	Sum basophil neutrophil counts	27863252	[0.017-0.033] unit decrease	0.02474309	EFO_0004833\|EFO_0005090
ENSG00000124782	rs9379084	6	7231610	?	Heel bone mineral density	30048462	[0.032-0.045] unit increase	0.0389254	EFO_0009270
ENSG00000124782	rs2842352	6	7250804	?	Heel bone mineral density	30048462	[0.013-0.025] unit increase	0.0189983	EFO_0009270
ENSG00000124782	rs9379084	6	7231610	G	Heel bone mineral density	30598549	[0.028-0.04] unit increase	0.0340199	EFO_0009270
ENSG00000124782	rs3904600	6	7109432	?	Balding type 1	30595370			EFO_0007825
ENSG00000124782	rs2714338	6	7250727	?	Balding type 1	30595370			EFO_0007825
ENSG00000124782	rs9379084	6	7231610	?	Type 2 diabetes	30595370			EFO_0001360
ENSG00000124782	rs687467	6	7127843	?	Lung function (FVC)	30595370			EFO_0004312
ENSG00000124782	rs3904600	6	7109432	?	Waist-hip ratio	30595370			EFO_0004343
ENSG00000124782	rs1285886	6	7140598	?	White blood cell count	30595370			EFO_0004308
ENSG00000124782	rs75757892	6	7232156	?	Red blood cell count	30595370			EFO_0004305
ENSG00000124782	rs4960289	6	7146117	?	Lung function (FEV1/FVC)	30595370			EFO_0004713
ENSG00000124782	rs1334576	6	7211585	A	Pulse pressure	30224653	[0.081-0.149] unit decrease	0.1149	EFO_0005763
ENSG00000124782	rs76052955	6	7213674	A	Pulse pressure	30578418	[0.11-0.21] mmHg increase	0.1613	EFO_0005763
ENSG00000124782	rs9379084	6	7231610	?	Heel bone mineral density	30595370			EFO_0009270
ENSG00000124782	rs9379084	6	7231610	A	Breast cancer	29059683	[0.028-0.069] unit increase	0.0486	EFO_0000305
ENSG00000124782	rs1334576	6	7211585	G	Waist-to-hip ratio adjusted for BMI (additive genetic model)	30778226	[0.013-0.021] unit increase	0.0171	EFO_0007788
ENSG00000124782	rs1334576	6	7211585	G	Waist-to-hip ratio adjusted for BMI (additive genetic model)	30778226	[0.012-0.021] unit increase	0.0166	EFO_0007788
ENSG00000124782	rs1334576	6	7211585	G	Waist-to-hip ratio adjusted for BMI (additive genetic model)	30778226	[0.015-0.027] unit increase	0.0209	EFO_0007788
ENSG00000124782	rs1334576	6	7211585	G	Waist-to-hip ratio adjusted for BMI (additive genetic model)	30778226	[0.0079-0.0201] unit increase	0.014	EFO_0007788
ENSG00000124782	rs1334576	6	7211585	G	Waist-to-hip ratio adjusted for BMI (additive genetic model)	30778226	[0.014-0.026] unit increase	0.0202	EFO_0007788
ENSG00000124782	rs9379084	6	7231610	G	Type 2 diabetes	29632382	[1.06-1.11]	1.08	EFO_0001360
ENSG00000124782	rs9379084	6	7231610	G	Type 2 diabetes (adjusted for BMI)	29632382	[1.07-1.13]	1.1	EFO_0001360
ENSG00000124782	rs9379084	6	7231610	G	Type 2 diabetes	29632382	[1.07-1.13]	1.1	EFO_0001360
ENSG00000124782	rs9379084	6	7231610	G	Type 2 diabetes (adjusted for BMI)	29632382	[1.06-1.12]	1.09	EFO_0001360
ENSG00000124782	rs35742417	6	7247111	C	Type 2 diabetes	29632382	[1.03-1.06]	1.04	EFO_0001360
ENSG00000124782	rs35742417	6	7247111	C	Type 2 diabetes (adjusted for BMI)	29632382	[1.02-1.06]	1.04	EFO_0001360
ENSG00000124782	rs35742417	6	7247111	C	Type 2 diabetes	29632382	(1.02-1.06)	1.04	EFO_0001360
ENSG00000124782	rs35742417	6	7247111	C	Type 2 diabetes (adjusted for BMI)	29632382	[1.02-1.06]	1.04	EFO_0001360

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000124782's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000124782	RREB1	59	42.982	ENSAPEG00000002682	-	73	45.902	Amphiprion_percula
ENSG00000124782	RREB1	97	80.000	ENSAPLG00000004726	RREB1	100	63.754	Anas_platyrhynchos
ENSG00000124782	RREB1	97	74.016	ENSACAG00000000520	RREB1	100	61.051	Anolis_carolinensis
ENSG00000124782	RREB1	100	98.529	ENSANAG00000029040	RREB1	100	94.792	Aotus_nancymaae
ENSG00000124782	RREB1	99	67.470	ENSAMXG00000019028	rreb1a	94	45.559	Astyanax_mexicanus
ENSG00000124782	RREB1	76	73.600	ENSAMXG00000015314	rreb1b	96	43.486	Astyanax_mexicanus
ENSG00000124782	RREB1	100	98.780	ENSCJAG00000021358	RREB1	100	95.475	Callithrix_jacchus
ENSG00000124782	RREB1	100	96.341	ENSCAFG00000009527	RREB1	100	88.180	Canis_familiaris
ENSG00000124782	RREB1	100	96.341	ENSCAFG00020013260	RREB1	100	81.492	Canis_lupus_dingo
ENSG00000124782	RREB1	100	98.780	ENSCCAG00000021905	RREB1	100	95.249	Cebus_capucinus
ENSG00000124782	RREB1	100	99.390	ENSCATG00000043662	RREB1	100	98.263	Cercocebus_atys
ENSG00000124782	RREB1	100	99.390	ENSCSAG00000007376	RREB1	100	96.670	Chlorocebus_sabaeus
ENSG00000124782	RREB1	99	86.667	ENSCPBG00000008709	RREB1	100	65.133	Chrysemys_picta_bellii
ENSG00000124782	RREB1	100	99.390	ENSCANG00000032835	RREB1	100	96.979	Colobus_angolensis_palliatus
ENSG00000124782	RREB1	91	57.386	ENSCSEG00000018342	rreb1a	88	50.980	Cynoglossus_semilaevis
ENSG00000124782	RREB1	95	63.910	ENSDARG00000063701	rreb1a	92	62.245	Danio_rerio
ENSG00000124782	RREB1	100	96.341	ENSDORG00000006979	Rreb1	99	87.793	Dipodomys_ordii
ENSG00000124782	RREB1	100	96.341	ENSEASG00005012054	RREB1	100	82.379	Equus_asinus_asinus
ENSG00000124782	RREB1	100	96.341	ENSECAG00000018169	RREB1	94	88.713	Equus_caballus
ENSG00000124782	RREB1	98	86.466	ENSFALG00000013231	RREB1	96	63.673	Ficedula_albicollis
ENSG00000124782	RREB1	100	95.588	ENSFDAG00000004213	RREB1	96	68.487	Fukomys_damarensis
ENSG00000124782	RREB1	100	84.756	ENSGALG00000012799	RREB1	100	63.093	Gallus_gallus
ENSG00000124782	RREB1	92	77.080	ENSGAGG00000002213	RREB1	100	63.074	Gopherus_agassizii
ENSG00000124782	RREB1	100	99.486	ENSGGOG00000004561	RREB1	100	99.169	Gorilla_gorilla
ENSG00000124782	RREB1	93	62.092	ENSLBEG00000013512	rreb1a	85	50.980	Labrus_bergylta
ENSG00000124782	RREB1	99	77.439	ENSLACG00000009283	RREB1	99	54.340	Latimeria_chalumnae
ENSG00000124782	RREB1	93	76.562	ENSLOCG00000011702	rreb1b	96	51.724	Lepisosteus_oculatus
ENSG00000124782	RREB1	100	93.382	ENSLAFG00000005300	RREB1	100	78.100	Loxodonta_africana
ENSG00000124782	RREB1	100	99.390	ENSMFAG00000000389	RREB1	100	98.187	Macaca_fascicularis
ENSG00000124782	RREB1	100	99.390	ENSMMUG00000007852	RREB1	100	97.961	Macaca_mulatta
ENSG00000124782	RREB1	100	99.390	ENSMNEG00000038556	RREB1	100	98.187	Macaca_nemestrina
ENSG00000124782	RREB1	100	99.390	ENSMLEG00000040965	RREB1	100	98.187	Mandrillus_leucophaeus
ENSG00000124782	RREB1	88	88.966	ENSMGAG00000003910	RREB1	100	62.829	Meleagris_gallopavo
ENSG00000124782	RREB1	100	95.244	ENSMICG00000003683	RREB1	100	91.053	Microcebus_murinus
ENSG00000124782	RREB1	100	89.706	ENSMODG00000009892	RREB1	100	70.922	Monodelphis_domestica
ENSG00000124782	RREB1	100	95.732	ENSMPUG00000000558	RREB1	100	82.452	Mustela_putorius_furo
ENSG00000124782	RREB1	100	96.341	ENSMLUG00000013153	RREB1	100	81.935	Myotis_lucifugus
ENSG00000124782	RREB1	100	96.341	ENSNGAG00000021506	Rreb1	100	83.737	Nannospalax_galili
ENSG00000124782	RREB1	74	72.143	ENSNBRG00000016744	rreb1a	85	54.082	Neolamprologus_brichardi
ENSG00000124782	RREB1	100	99.390	ENSNLEG00000011554	RREB1	100	99.018	Nomascus_leucogenys
ENSG00000124782	RREB1	100	88.415	ENSMEUG00000015377	RREB1	100	72.629	Notamacropus_eugenii
ENSG00000124782	RREB1	100	90.441	ENSOPRG00000001966	RREB1	88	77.527	Ochotona_princeps
ENSG00000124782	RREB1	100	85.403	ENSODEG00000007124	RREB1	100	77.876	Octodon_degus
ENSG00000124782	RREB1	88	61.194	ENSOMEG00000001389	rreb1a	68	94.118	Oryzias_melastigma
ENSG00000124782	RREB1	100	95.732	ENSOGAG00000025755	RREB1	100	81.353	Otolemur_garnettii
ENSG00000124782	RREB1	100	99.743	ENSPPAG00000037017	RREB1	100	99.698	Pan_paniscus
ENSG00000124782	RREB1	100	96.341	ENSPPRG00000012144	RREB1	100	83.771	Panthera_pardus
ENSG00000124782	RREB1	100	99.743	ENSPTRG00000017697	RREB1	100	99.622	Pan_troglodytes
ENSG00000124782	RREB1	100	99.390	ENSPANG00000019553	RREB1	100	97.961	Papio_anubis
ENSG00000124782	RREB1	92	63.934	ENSPKIG00000006372	rreb1b	91	53.403	Paramormyrops_kingsleyae
ENSG00000124782	RREB1	88	90.345	ENSPSIG00000006582	RREB1	100	63.435	Pelodiscus_sinensis
ENSG00000124782	RREB1	100	94.118	ENSPEMG00000014153	Rreb1	100	80.201	Peromyscus_maniculatus_bairdii
ENSG00000124782	RREB1	92	82.418	ENSPCIG00000012644	RREB1	100	70.413	Phascolarctos_cinereus
ENSG00000124782	RREB1	100	99.100	ENSPPYG00000016204	RREB1	100	97.819	Pongo_abelii
ENSG00000124782	RREB1	100	96.324	ENSPCOG00000014821	RREB1	100	91.573	Propithecus_coquereli
ENSG00000124782	RREB1	100	96.341	ENSPVAG00000014081	RREB1	100	82.924	Pteropus_vampyrus
ENSG00000124782	RREB1	96	65.409	ENSPNAG00000000486	rreb1a	89	51.600	Pygocentrus_nattereri
ENSG00000124782	RREB1	100	93.382	ENSRNOG00000015701	Rreb1	100	79.263	Rattus_norvegicus
ENSG00000124782	RREB1	100	99.390	ENSRROG00000039603	RREB1	100	97.508	Rhinopithecus_roxellana
ENSG00000124782	RREB1	100	98.780	ENSSBOG00000025257	RREB1	100	94.800	Saimiri_boliviensis_boliviensis
ENSG00000124782	RREB1	100	88.971	ENSSHAG00000005295	RREB1	91	83.184	Sarcophilus_harrisii
ENSG00000124782	RREB1	88	70.470	ENSSFOG00015001117	rreb1b	93	48.257	Scleropages_formosus
ENSG00000124782	RREB1	88	88.276	ENSSPUG00000007686	RREB1	100	63.300	Sphenodon_punctatus
ENSG00000124782	RREB1	100	84.756	ENSTGUG00000002309	RREB1	100	65.530	Taeniopygia_guttata
ENSG00000124782	RREB1	100	95.122	ENSUAMG00000003741	RREB1	100	82.864	Ursus_americanus
ENSG00000124782	RREB1	100	96.341	ENSVVUG00000005050	RREB1	96	88.444	Vulpes_vulpes
ENSG00000124782	RREB1	96	81.529	ENSXETG00000015435	rreb1	98	55.556	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0000122	negative regulation of transcription by RNA polymerase II	20133935.	IMP	Process
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	21873635.	IBA	Function
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	8816445.	IDA	Function
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	21873635.	IBA	Function
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	20133935.	IMP	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	21873635.	IBA	Function
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	8816445.	IDA	Function
GO:0001650	fibrillar center	-	IDA	Component
GO:0003700	DNA-binding transcription factor activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	9305772.	TAS	Component
GO:0005737	cytoplasm	9305772.	TAS	Component
GO:0006355	regulation of transcription, DNA-templated	9305772.	TAS	Process
GO:0006366	transcription by RNA polymerase II	8816445.	TAS	Process
GO:0007265	Ras protein signal transduction	8816445.	TAS	Process
GO:0007275	multicellular organism development	8816445.	TAS	Process
GO:0010634	positive regulation of epithelial cell migration	18394891.	IMP	Process
GO:0016604	nuclear body	9305772.	TAS	Component
GO:0016607	nuclear speck	-	IDA	Component
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	18394891.	IMP	Process
GO:0045893	positive regulation of transcription, DNA-templated	9305772.	TAS	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	8816445.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	18394891.	IMP	Process
GO:1903691	positive regulation of wound healing, spreading of epidermal cells	18394891.	IMP	Process
GO:2000394	positive regulation of lamellipodium morphogenesis	18394891.	IMP	Process

EuRBPDB

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PPI

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