EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
16631123	Expression analysis and prognostic significance of the SRA1 gene, in ovarian cancer.	Biochem Biophys Res Commun	2006 Jun 2	Leoutsakou T	-
15493872	SR-A1, a member of the human pre-mRNA splicing factor family, and its expression in colon cancer progression.	Biol Chem	2004 Sep	Mathioudaki K	-
29787824	Discovery and expression analysis of novel transcripts of the human SR-related CTD-associated factor 1 (SCAF1) gene in human cancer cells using Next-Generation Sequencing.	Gene	2018 Sep 5	Adamopoulos PG	doi: 10.1016/j.gene.2018.05.044

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr19	49654417	Missense_Mutation	rs779360567	Q1129E	0.2
ACC	chr19	49653577	Missense_Mutation	novel	S1063C	0.17
BLCA	chr19	49651476	Missense_Mutation	rs770076860	R363W	0.43
BLCA	chr19	49652698	Missense_Mutation	NA	R770Q	0.44
BLCA	chr19	49651467	Missense_Mutation	novel	E360K	0.65
BLCA	chr19	49652410	Missense_Mutation	NA	S674W	0.3
BLCA	chr19	49645063	Missense_Mutation	novel	E13K	0.08
BLCA	chr19	49652520	Missense_Mutation	NA	D711N	0.59
BRCA	chr19	49653431	Frame_Shift_Del	novel	*A1015Lfs92**	1
BRCA	chr19	49654735	Silent	novel	P1161P	0.49
BRCA	chr19	49657880	Silent	rs754907754	A1246A	0.58
BRCA	chr19	49645401	Silent	NA	P52P	0.14
BRCA	chr19	49658619	3'UTR	novel		0.15
BRCA	chr19	49652709	Missense_Mutation	NA	D774Y	0.16
BRCA	chr19	49652803	Nonsense_Mutation	NA	S805*	0.33
CESC	chr19	49645110	Silent	rs752202548	T28T	0.43
CESC	chr19	49651286	Silent	NA	E299E	0.28
CESC	chr19	49652721	Missense_Mutation	rs751197713	R778W	0.1
CESC	chr19	49652340	Missense_Mutation	novel	G651S	0.36
CESC	chr19	49652671	Missense_Mutation	rs772383494	S761C	0.25
CESC	chr19	49645362	Missense_Mutation	novel	I39M	0.18
CESC	chr19	49651284	Missense_Mutation	novel	E299Q	0.19
CHOL	chr19	49652728	In_Frame_Del	novel	D785_R790del	0.08
COAD	chr19	49658262	Missense_Mutation	novel	R1268W	0.25
COAD	chr19	49650881	Silent	rs769175493	S164S	0.1
COAD	chr19	49645115	Missense_Mutation	novel	S30Y	0.28
COAD	chr19	49651154	Silent	rs746197159	G255G	0.43
COAD	chr19	49652813	Silent	rs771383795	P808P	0.34
COAD	chr19	49652955	Missense_Mutation	novel	S856T	0.34
COAD	chr19	49646613	Missense_Mutation	novel	L117M	0.21
COAD	chr19	49658305	Missense_Mutation	rs760624103	R1282H	0.37
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.26
COAD	chr19	49645110	Silent	rs752202548	T28T	0.34
COAD	chr19	49658318	Frame_Shift_Del	novel	*P1288Qfs57**	0.5
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.38
COAD	chr19	49654731	Missense_Mutation	NA	G1160V	0.43
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.13
COAD	chr19	49653320	Silent	rs575769784	P977P	0.55
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.5
COAD	chr19	49653098	Missense_Mutation	novel	K903N	0.14
COAD	chr19	49657767	Missense_Mutation	novel	K1209E	0.31
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.32
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.46
COAD	chr19	49651059	Nonsense_Mutation	novel	R224*	0.25
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.57
COAD	chr19	49654727	Missense_Mutation	NA	P1159T	0.28
COAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.37
COAD	chr19	49653548	Silent	rs375665533	A1053A	0.41
COAD	chr19	49645110	Silent	rs752202548	T28T	0.17
ESCA	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.78
ESCA	chr19	49650871	Missense_Mutation	novel	S161C	0.56
ESCA	chr19	49658483	3'UTR	novel		0.61
ESCA	chr19	49654700	Missense_Mutation	novel	P1150A	0.11
ESCA	chr19	49645083	Silent	rs200923973	G19G	0.35
GBM	chr19	49646192	Missense_Mutation	novel	D84G	0.23
GBM	chr19	49652867	Silent	novel	C826C	0.51
GBM	chr19	49658259	Frame_Shift_Ins	novel	*V1267Afs79**	0.29
GBM	chr19	49658261	In_Frame_Ins	novel	V1267_R1268insVLTLCF	0.27
HNSC	chr19	49651358	Silent	rs372506690	D323D	0.5
HNSC	chr19	49654690	Missense_Mutation	novel	M1146I	0.09
HNSC	chr19	49654389	Silent	rs767686210	A1119A	0.25
HNSC	chr19	49646810	Missense_Mutation	novel	A153V	0.5
HNSC	chr19	49654855	Frame_Shift_Ins	novel	*D1203Gfs4**	0.26
KIRP	chr19	49657789	Missense_Mutation	novel	R1216L	0.25
KIRP	chr19	49652265	Missense_Mutation	novel	R626W	0.51
KIRP	chr19	49652872	Missense_Mutation	novel	S828Y	0.35
KIRP	chr19	49658295	Missense_Mutation	NA	K1279Q	0.5
LGG	chr19	49653443	Silent	NA	R1018R	0.97
LGG	chr19	49652487	Missense_Mutation	rs771601240	A700T	0.48
LGG	chr19	49651340	Silent	rs370259405	D317D	0.16
LIHC	chr19	49653621	Missense_Mutation	novel	V1078F	0.49
LIHC	chr19	49650924	Missense_Mutation	NA	T179P	0.32
LIHC	chr19	49652751	Missense_Mutation	novel	R788W	0.23
LUAD	chr19	49645134	Splice_Region	novel	L36L	0.34
LUAD	chr19	49645041	Silent	novel	D5D	0.19
LUAD	chr19	49651513	Missense_Mutation	novel	G375V	0.2
LUAD	chr19	49646780	Missense_Mutation	novel	P143H	0.32
LUAD	chr19	49654714	Silent	novel	S1154S	0.09
LUAD	chr19	49650899	Silent	novel	T170T	0.58
LUAD	chr19	49645412	Splice_Site	NA	X56_splice	0.49
LUAD	chr19	49646559	Missense_Mutation	novel	G99W	0.18
LUAD	chr19	49646117	Missense_Mutation	rs146838422	R59Q	0.16
LUAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.83
LUAD	chr19	49650926	Silent	novel	T179T	0.18
LUAD	chr19	49658300	Silent	rs575013180	H1280H	0.39
LUSC	chr19	49654703	Missense_Mutation	novel	V1151L	0.75
LUSC	chr19	49653656	Silent	novel	P1089P	0.45
LUSC	chr19	49652445	Missense_Mutation	novel	V686L	0.33
LUSC	chr19	49651999	Missense_Mutation	NA	S537L	0.75
OV	chr19	49658458	3'UTR	novel		0.43
OV	chr19	49651077	Missense_Mutation	NA	P230A	0.44
OV	chr19	49650968	Silent	novel	A193A	0.15
OV	chr19	49651081	Missense_Mutation	novel	F231C	0.29
OV	chr19	49650930	Missense_Mutation	novel	D181H	0.68
OV	chr19	49651077	Missense_Mutation	NA	P230A	0.84
OV	chr19	49645026	5'UTR	novel		0.29
OV	chr19	49650909	Missense_Mutation	novel	H174D	0.75
OV	chr19	49652709	Missense_Mutation	NA	D774Y	0.35
OV	chr19	49651075	Missense_Mutation	NA	D229G	0.87
OV	chr19	49651074	Missense_Mutation	novel	D229N	0.61
PAAD	chr19	49651375	Missense_Mutation	rs754690731	P329L	0.24
PAAD	chr19	49651053	Missense_Mutation	novel	A222T	0.08
PAAD	chr19	49657799	Silent	rs777006031	E1219E	0.15
PCPG	chr19	49653512	Nonsense_Mutation	novel	P1042*	0.31
PRAD	chr19	49652845	Missense_Mutation	novel	S819F	0.53
PRAD	chr19	49651393	Missense_Mutation	rs749233252	T335M	0.23
PRAD	chr19	49651394	Silent	novel	T335T	0.31
READ	chr19	49652529	Missense_Mutation	rs756716435	D714N	0.38
READ	chr19	49645363	Missense_Mutation	novel	Q40K	0.08
READ	chr19	49650955	Frame_Shift_Del	novel	*S191Pfs120**	0.13
READ	chr19	49652749	Missense_Mutation	novel	D787G	0.32
SARC	chr19	49646750	Missense_Mutation	rs759490334	R133Q	0.14
SARC	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.52
SKCM	chr19	49658328	Missense_Mutation	novel	P1290S	0.41
SKCM	chr19	49654737	Missense_Mutation	NA	S1162F	0.39
SKCM	chr19	49654797	Missense_Mutation	NA	P1182L	0.58
SKCM	chr19	49652681	Silent	novel	R764R	0.42
SKCM	chr19	49651275	Missense_Mutation	NA	R296C	0.37
SKCM	chr19	49651386	Missense_Mutation	NA	P333S	0.52
SKCM	chr19	49652438	Silent	novel	R683R	0.35
SKCM	chr19	49658320	Missense_Mutation	novel	P1287L	0.29
SKCM	chr19	49658321	Silent	novel	P1287P	0.25
SKCM	chr19	49658329	Missense_Mutation	NA	P1290L	0.75
SKCM	chr19	49654852	Silent	NA	G1200G	0.62
SKCM	chr19	49653011	Silent	NA	S874S	0.6
SKCM	chr19	49645048	Nonsense_Mutation	NA	R8*	0.29
SKCM	chr19	49646131	Nonsense_Mutation	NA	R64*	0.58
SKCM	chr19	49654725	Missense_Mutation	NA	P1158L	0.34
SKCM	chr19	49646768	Missense_Mutation	novel	P139L	0.67
SKCM	chr19	49646769	Silent	rs764431608	P139P	0.63
SKCM	chr19	49652876	Silent	NA	R829R	0.4
SKCM	chr19	49651448	Silent	NA	F353F	0.33
SKCM	chr19	49646583	Missense_Mutation	rs267605589	P107S	0.41
SKCM	chr19	49654796	Missense_Mutation	NA	P1182S	0.14
SKCM	chr19	49646772	Silent	rs754146923	I140I	0.74
SKCM	chr19	49654661	Missense_Mutation	novel	H1137Y	0.23
SKCM	chr19	49652677	Missense_Mutation	novel	S763F	0.6
SKCM	chr19	49652783	Silent	novel	P798P	0.5
SKCM	chr19	49646529	Silent	novel	L89L	0.59
SKCM	chr19	49652640	Missense_Mutation	rs779551629	R751W	0.38
SKCM	chr19	49653006	Missense_Mutation	NA	R873C	0.14
SKCM	chr19	49652688	Missense_Mutation	NA	G767R	0.78
SKCM	chr19	49653177	Missense_Mutation	NA	G930R	0.62
SKCM	chr19	49652848	Missense_Mutation	NA	S820L	0.17
SKCM	chr19	49653017	Silent	novel	F876F	0.35
SKCM	chr19	49645123	Missense_Mutation	NA	A33S	0.13
SKCM	chr19	49651156	Missense_Mutation	novel	S256F	0.43
STAD	chr19	49652932	Missense_Mutation	NA	T848S	0.2
STAD	chr19	49654785	Frame_Shift_Del	novel	*P1180Hfs10**	0.4
STAD	chr19	49652381	Silent	NA	A664A	0.42
STAD	chr19	49652497	Missense_Mutation	NA	R703Q	0.41
STAD	chr19	49645109	Missense_Mutation	rs767108871	T28M	0.21
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.2
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.35
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.33
STAD	chr19	49653364	Missense_Mutation	NA	S992L	0.71
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.5
STAD	chr19	49654774	Silent	rs61741246	G1174G	0.43
STAD	chr19	49651149	Missense_Mutation	NA	T254A	0.07
STAD	chr19	49653006	Missense_Mutation	NA	R873C	0.35
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.35
STAD	chr19	49653443	Silent	NA	R1018R	0.32
STAD	chr19	49658265	Missense_Mutation	novel	A1269T	0.2
STAD	chr19	49658278	Missense_Mutation	NA	R1273H	0.59
STAD	chr19	49652433	Missense_Mutation	NA	R682C	0.26
STAD	chr19	49646146	Missense_Mutation	NA	R69W	0.32
STAD	chr19	49658318	Frame_Shift_Del	novel	*P1288Qfs57**	0.18
STAD	chr19	49646606	Silent	NA	R114R	0.22
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.28
STAD	chr19	49654375	Missense_Mutation	novel	E1115Q	0.18
STAD	chr19	49652436	Frame_Shift_Ins	novel	*A685Gfs27**	0.4
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.61
STAD	chr19	49652437	Frame_Shift_Del	NA	*A685Pfs53**	0.39
STAD	chr19	49653451	Missense_Mutation	NA	A1021V	0.3
STAD	chr19	49654785	Frame_Shift_Del	novel	*P1180Hfs10**	0.37
STAD	chr19	49651359	Missense_Mutation	NA	A324T	0.23
STAD	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.67
TGCT	chr19	49645412	Splice_Site	NA	X56_splice	0.19
TGCT	chr19	49646567	Silent	novel	V101V	0.24
THCA	chr19	49651072	Missense_Mutation	NA	Y228C	0.34
THCA	chr19	49651366	Frame_Shift_Ins	novel	*T327Hfs19**	0.07
UCEC	chr19	49652791	Missense_Mutation	rs375947171	S801L	0.22
UCEC	chr19	49650881	Silent	rs769175493	S164S	0.46
UCEC	chr19	49651064	Silent	rs763988897	F225F	0.21
UCEC	chr19	49652722	Missense_Mutation	rs780683585	R778Q	0.65
UCEC	chr19	49651429	Missense_Mutation	novel	A347V	0.38
UCEC	chr19	49652644	Missense_Mutation	novel	R752H	0.21
UCEC	chr19	49653527	Silent	rs762617715	T1046T	0.48
UCEC	chr19	49645110	Silent	rs752202548	T28T	0.5
UCEC	chr19	49651276	Missense_Mutation	novel	R296H	0.3
UCEC	chr19	49651359	Missense_Mutation	NA	A324T	0.52
UCEC	chr19	49646816	Missense_Mutation	NA	R155K	0.17
UCEC	chr19	49653207	Missense_Mutation	NA	V940M	0.28
UCEC	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.44
UCEC	chr19	49651241	Missense_Mutation	rs760729742	E284D	0.4
UCEC	chr19	49651111	Missense_Mutation	novel	P241L	0.11
UCEC	chr19	49652573	Silent	novel	R728R	0.3
UCEC	chr19	49658305	Missense_Mutation	rs760624103	R1282H	0.6
UCEC	chr19	49645109	Missense_Mutation	rs767108871	T28M	0.26
UCEC	chr19	49652986	Missense_Mutation	novel	F866S	0.27
UCEC	chr19	49652991	Missense_Mutation	novel	R868C	0.42
UCEC	chr19	49645110	Silent	rs752202548	T28T	0.44
UCEC	chr19	49653441	Nonsense_Mutation	NA	R1018*	0.53
UCEC	chr19	49658215	Missense_Mutation	novel	H1252R	0.3
UCEC	chr19	49654785	Frame_Shift_Del	NA	*T1181Pfs28**	0.37
UCEC	chr19	49652554	Missense_Mutation	NA	P722L	0.29
UCEC	chr19	49657870	Missense_Mutation	novel	L1243P	0.13
UCEC	chr19	49652478	Missense_Mutation	novel	D697N	0.28
UCEC	chr19	49652903	Silent	novel	A838A	0.38
UCEC	chr19	49651349	Silent	novel	P320P	0.43
UCEC	chr19	49652772	Missense_Mutation	novel	A795T	0.24
UCEC	chr19	49657881	Missense_Mutation	novel	V1247I	0.48
UCEC	chr19	49653571	Missense_Mutation	rs768633107	A1061V	0.27
UCEC	chr19	49654663	Silent	novel	H1137H	0.3
UCEC	chr19	49654697	Missense_Mutation	novel	A1149T	0.47
UCEC	chr19	49652679	Missense_Mutation	rs764284987	R764W	0.36
UCEC	chr19	49657797	Missense_Mutation	NA	E1219K	0.09
UCEC	chr19	49654713	Missense_Mutation	novel	S1154Y	0.32
UCEC	chr19	49646145	Silent	novel	C68C	0.45
UCEC	chr19	49654785	Frame_Shift_Del	novel	*P1180Hfs10**	0.4
UCEC	chr19	49652954	Silent	novel	A855A	0.35
UCEC	chr19	49652775	Silent	rs753735532	R796R	0.34
UCS	chr19	49651358	Silent	rs372506690	D323D	0.6
UCS	chr19	49652486	Silent	novel	F699F	0.27

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0881	0.027508
KIRP	DEL	0.0486	0.054726
LUAD	DEL	0.2539	1.5526e-05
LUSC	DEL	0.2116	1.1877e-06
PAAD	DEL	0.0815	0.035089
READ	DEL	0.0909	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1786	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0048	Kaplan-Meier Survival Analysis
MESO	0.00043	Kaplan-Meier Survival Analysis
ACC	0.00027	Kaplan-Meier Survival Analysis
SKCM	0.00074	Kaplan-Meier Survival Analysis
PRAD	0.0056	Kaplan-Meier Survival Analysis
KIRP	0.025	Kaplan-Meier Survival Analysis
COAD	0.0038	Kaplan-Meier Survival Analysis
PAAD	0.015	Kaplan-Meier Survival Analysis
BLCA	0.041	Kaplan-Meier Survival Analysis
LAML	0.013	Kaplan-Meier Survival Analysis
LIHC	0.0071	Kaplan-Meier Survival Analysis
LGG	0.017	Kaplan-Meier Survival Analysis
LUAD	0.011	Kaplan-Meier Survival Analysis
UVM	0.039	Kaplan-Meier Survival Analysis
OV	0.043	Kaplan-Meier Survival Analysis

Description

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000126461 (Gene tree)
Gene ID: 58506
Gene Symbol: SCAF1
Alias: SR-A1|FLJ00034
Full Name: SR-related CTD associated factor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 18,147 bases
Position: chr19:49,640,503-49,658,649
Accession: 30403
RBP type: non-canonical RBP
Summary: (SR-Related CTD Associated Factor 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA binding and protein domain specific binding. An important paralog of this gene is PHRF1.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000595242	SCAF1-202	463	-	ENSP00000472276	119 (aa)	-	M0R232
ENST00000598359	SCAF1-203	662	-	ENSP00000473210	203 (aa)	-	M0R3G4
ENST00000360565	SCAF1-201	4306	XM_005259122	ENSP00000353769	1312 (aa)	XP_005259179	Q9H7N4
ENST00000601038	SCAF1-204	491	-	ENSP00000472649	98 (aa)	-	M0R2L3

Gene Model

Click here to download ENSG00000126461's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000126461	rs7508148	19	49648885	?	Schizophrenia	29483656	[1.06-1.1]	1.08	EFO_0000692
ENSG00000126461	rs189349094	19	49642643	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000126461	rs76387513	19	49658008	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000126461	rs61743199	19	49657834	?	Heel bone mineral density	30595370			EFO_0009270
ENSG00000126461	rs189349094	19	49642643	?	Cardiovascular disease	30595370			EFO_0000319

Protein-Protein Interaction (PPI)

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Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000126461	SCAF1	100	90.909	ENSMUSG00000038406	Scaf1	100	97.674	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0006366	transcription by RNA polymerase II	-	IEA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0019904	protein domain specific binding	-	IEA	Function
GO:0099122	RNA polymerase II C-terminal domain binding	15992770.	IPI	Function

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.