EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23696030	Clinicopathological and prognostic significance of myofibrillogenesis regulator-1 protein expression in pancreatic ductal adenocarcinoma.	Tumour Biol	2013 Oct	Zhao CY	doi: 10.1007/s13277-013-0862-4
25066297	Phosphorylation of myofibrillogenesis regulator-1 activates the MAPK signaling pathway and induces proliferation and migration in human breast cancer MCF7 cells.	FEBS Lett	2014 Aug 25	Gong Y	doi: 10.1016/j.febslet.2014.07.018
23082061	Myofibrillogenesis regulator-1 overexpression is associated with poor prognosis of gastric cancer patients.	World J Gastroenterol	2012 Oct 14	Guo J	doi: 10.3748/wjg.v18.i38.5434.
22780969	[Expression of a novel biomarker, MR-1S, in ovarian carcinoma and its biological significance].	Zhonghua Zhong Liu Za Zhi	2012 Mar	Lu RQ	doi: 10.3760/cma.j.issn.0253-3766.2012.03.004.
27005424	Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.	Hum Mol Genet	2016 Jun 1	Orlando G	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr2	218272857	Intron	novel		0.46
BLCA	chr2	218344957	Silent	NA	L378L	0.25
BLCA	chr2	218272576	Intron	novel		0.49
BLCA	chr2	218272847	Intron	novel		0.19
BLCA	chr2	218271450	Missense_Mutation	novel	S46F	0.7
BLCA	chr2	218343574	Missense_Mutation	novel	L286I	0.29	Lactamase_B
BRCA	chr2	218346607	3'UTR	rs533899847		0.31
BRCA	chr2	218344893	Missense_Mutation	NA	G357A	0.12
BRCA	chr2	218272620	Intron	novel		0.14
BRCA	chr2	218346583	3'UTR	novel		0.15
BRCA	chr2	218272792	Intron	novel		0.36
BRCA	chr2	218272570	Intron	NA		0.25
BRCA	chr2	218272919	Intron	novel		0.36
BRCA	chr2	218340125	Missense_Mutation	novel	D150V	0.1
BRCA	chr2	218344564	Silent	NA	K326K	0.56
CESC	chr2	218270471	5'Flank	rs570619432		0.32
CESC	chr2	218346301	3'UTR	novel		0.25
COAD	chr2	218272852	Intron	novel		0.41
COAD	chr2	218272809	Intron	novel		0.46
COAD	chr2	218272626	Intron	novel		0.08
COAD	chr2	218342140	Silent	novel	G259G	0.13
COAD	chr2	218323315	Intron	NA		0.36
COAD	chr2	218344986	3'UTR	rs760022142		0.53
COAD	chr2	218340767	Silent	NA	L169L	0.27
COAD	chr2	218272748	Intron	NA		0.43
COAD	chr2	218339811	Missense_Mutation	NA	G89W	0.22
COAD	chr2	218343503	Missense_Mutation	rs759669801	R262Q	0.21	Lactamase_B
COAD	chr2	218345124	3'UTR	novel		0.23
COAD	chr2	218340767	Missense_Mutation	NA	L169M	0.28	Lactamase_B
GBM	chr2	218340769	Silent	novel	L169L	0.48
GBM	chr2	218342028	Missense_Mutation	rs777574834	R222Q	0.21	Lactamase_B
HNSC	chr2	218340071	Missense_Mutation	novel	S132N	0.18
HNSC	chr2	218272853	Intron	novel		0.08
HNSC	chr2	218272853	Intron	novel		0.13
HNSC	chr2	218343565	Missense_Mutation	novel	D283N	0.32	Lactamase_B
KIRP	chr2	218340772	Frame_Shift_Ins	novel	*T171Dfs13**	0.39	Lactamase_B
KIRP	chr2	218272855	Intron	novel		0.34
LAML	chr2	218344821	Missense_Mutation	novel	L333Q	0.65
LUAD	chr2	218272678	Intron	novel		0.08
LUAD	chr2	218342092	Silent	novel	Y243Y	0.27
LUAD	chr2	218342026	Missense_Mutation	rs749437540	I221M	0.11	Lactamase_B
LUAD	chr2	218340044	Missense_Mutation	NA	P123R	0.32
LUSC	chr2	218344806	Splice_Site	rs766885440	X329_splice	0.16
LUSC	chr2	218344808	Missense_Mutation	novel	C329G	0.19
LUSC	chr2	218339865	Missense_Mutation	novel	G107S	0.18
LUSC	chr2	218344948	Silent	novel	L375L	0.44
LUSC	chr2	218272631	Intron	novel		0.23
LUSC	chr2	218272666	Intron	novel		0.18
OV	chr2	218343555	Silent	NA	L279L	0.23
OV	chr2	218341540	Missense_Mutation	novel	H177Q	0.24	Lactamase_B
OV	chr2	218344901	Missense_Mutation	novel	P360S	0.22
OV	chr2	218344807	Splice_Site	NA	X329_splice	0.41
PAAD	chr2	218339825	Silent	novel	Y93Y	0.05
SARC	chr2	218346271	3'UTR	novel		0.2
SKCM	chr2	218340061	Missense_Mutation	rs777285859	D129N	0.36
SKCM	chr2	218342108	Missense_Mutation	NA	L249F	0.59	Lactamase_B
SKCM	chr2	218345102	3'UTR	novel		0.38
SKCM	chr2	218340046	Missense_Mutation	NA	I124V	0.15
SKCM	chr2	218340104	Missense_Mutation	NA	A143V	0.35
SKCM	chr2	218272834	Intron	rs1045663		0.64
SKCM	chr2	218270504	5'UTR	novel		0.36
SKCM	chr2	218342131	Silent	NA	F256F	0.29
SKCM	chr2	218339806	Nonsense_Mutation	NA	W87*	0.3
SKCM	chr2	218340055	Missense_Mutation	NA	L127F	0.52
SKCM	chr2	218345019	3'UTR	rs201679687		0.44
SKCM	chr2	218344936	Silent	novel	L371L	0.54
SKCM	chr2	218345012	3'UTR	novel		0.29
SKCM	chr2	218272718	Intron	novel		0.29
SKCM	chr2	218271416	Missense_Mutation	novel	H35Y	0.36
SKCM	chr2	218342131	Silent	NA	F256F	0.55
SKCM	chr2	218340057	Silent	NA	L127L	0.27
STAD	chr2	218344820	Missense_Mutation	NA	L333M	0.16
STAD	chr2	218344908	Missense_Mutation	NA	G362V	0.2
STAD	chr2	218272806	Intron	novel		0.46
STAD	chr2	218344827	Missense_Mutation	NA	E335G	0.27
TGCT	chr2	218344983	3'UTR	rs199958845		0.07
UCEC	chr2	218270442	5'Flank	novel		0.07
UCEC	chr2	218340767	Missense_Mutation	NA	L169M	0.07	Lactamase_B
UCEC	chr2	218271414	Missense_Mutation	rs146016925	S34Y	0.28
UCEC	chr2	218346355	3'UTR	novel		0.18
UCEC	chr2	218343503	Missense_Mutation	rs759669801	R262Q	0.52	Lactamase_B
UCEC	chr2	218271386	Missense_Mutation	NA	L25I	0.49
UCEC	chr2	218346763	3'UTR	novel		0.46
UCEC	chr2	218344485	Missense_Mutation	novel	F300C	0.32
UCEC	chr2	218339872	Missense_Mutation	novel	S109L	0.44
UCEC	chr2	218346588	3'UTR	novel		0.03
UCEC	chr2	218346754	3'UTR	NA		0.24
UCEC	chr2	218344501	Silent	NA	E305E	0.47
UCEC	chr2	218344925	Silent	NA	R368R	0.36
UCEC	chr2	218272784	Intron	novel		0.36
UCEC	chr2	218272866	Intron	novel		0.46
UCEC	chr2	218272616	Intron	rs748457296		0.35
UCEC	chr2	218271381	Missense_Mutation	novel	G23E	0.35
UCEC	chr2	218346196	3'UTR	novel		0.36
UCEC	chr2	218341583	Missense_Mutation	rs758791360	R192W	0.37	Lactamase_B
UCEC	chr2	218341556	Missense_Mutation	novel	D183Y	0.22	Lactamase_B
UCEC	chr2	218343520	Missense_Mutation	novel	A268T	0.33	Lactamase_B
UCEC	chr2	218346341	3'UTR	novel		0.36
UCEC	chr2	218346711	3'UTR	novel		0.48
UCEC	chr2	218346754	3'UTR	NA		0.43
UCEC	chr2	218346283	3'UTR	novel		0.41
UCEC	chr2	218342028	Missense_Mutation	rs777574834	R222Q	0.42	Lactamase_B
UCEC	chr2	218340029	Missense_Mutation	novel	G118E	0.48
UCEC	chr2	218340100	Silent	novel	L142L	0.32
UCEC	chr2	218339854	Missense_Mutation	rs768336954	R103H	0.25
UCEC	chr2	218272653	Intron	rs761460268		0.48
UCEC	chr2	218344819	Silent	novel	T332T	0.42
UCEC	chr2	218272792	Intron	novel		0.21
UCEC	chr2	218340128	Missense_Mutation	novel	P151H	0.33
UCEC	chr2	218346491	3'UTR	novel		0.24
UCEC	chr2	218344825	Silent	novel	G334G	0.52
UCEC	chr2	218272655	Intron	rs767306596		0.29
UCEC	chr2	218341565	Missense_Mutation	rs750121779	R186W	0.48	Lactamase_B
UCEC	chr2	218344569	Missense_Mutation	rs780464180	T328M	0.38

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.0625	0.0017831
HNSC	DEL	0.2165	1.278e-25
KIRC	AMP	0.1136	0.059566
KIRP	DEL	0.0382	5.174e-05
LUSC	DEL	0.2415	1.3904e-19
MESO	DEL	0.1264	0.014499
PAAD	AMP	0.0707	0.1091
PAAD	DEL	0.038	0.2014
READ	AMP	0.2061	0.14328
TGCT	AMP	0.1533	0.088103
THCA	AMP	0.002	0.075436
THCA	DEL	0.024	0.040844

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00011	Kaplan-Meier Survival Analysis
SARC	0.0049	Kaplan-Meier Survival Analysis
MESO	0.0097	Kaplan-Meier Survival Analysis
ACC	0.0049	Kaplan-Meier Survival Analysis
SKCM	0.0048	Kaplan-Meier Survival Analysis
LUSC	0.034	Kaplan-Meier Survival Analysis
BRCA	0.00087	Kaplan-Meier Survival Analysis
KIRP	0.041	Kaplan-Meier Survival Analysis
PCPG	0.013	Kaplan-Meier Survival Analysis
BLCA	0.002	Kaplan-Meier Survival Analysis
UCEC	0.035	Kaplan-Meier Survival Analysis
LIHC	0.011	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000127838 (Gene tree)
Gene ID: 25953
Gene Symbol: PNKD
Alias: DYT8|PDC|DKFZp564N1362|FPD1|MR-1|BRP17|FKSG19|TAHCCP2|KIAA1184|KIPP1184|MGC31943|PKND1|MR-1S
Full Name: PNKD metallo-beta-lactamase domain containing
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 76,402 bases
Position: chr2:218,270,392-218,346,793
Accession: 9153
RBP type: canonical RBP
Summary: This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000414400	Lactamase_B	PF00753.27	1.6e-10	1	1
ENSP00000258362	Lactamase_B	PF00753.27	2.3e-10	1	1
ENSP00000273077	Lactamase_B	PF00753.27	2.8e-10	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000258362	PNKD-202	2991	XM_017003772	ENSP00000258362	361 (aa)	XP_016859261	Q8N490
ENST00000273077	PNKD-203	3021	XM_017003771	ENSP00000273077	385 (aa)	XP_016859260	Q8N490
ENST00000436005	PNKD-204	978	-	ENSP00000414400	325 (aa)	-	Q8N490
ENST00000494954	PNKD-208	248	-	-	- (aa)	-	-
ENST00000469689	PNKD-205	1372	-	-	- (aa)	-	-
ENST00000483797	PNKD-207	209	-	-	- (aa)	-	-
ENST00000472650	PNKD-206	472	-	-	- (aa)	-	-
ENST00000248451	PNKD-201	758	-	ENSP00000248451	142 (aa)	-	Q8N490

Gene Model

Click here to download ENSG00000127838's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000127838	Inflammatory Bowel Diseases	4E-12	23128233
ENSG00000127838	Colitis, Ulcerative	2E-8	26192919
ENSG00000127838	Crohn Disease	4E-9	26192919
ENSG00000127838	Inflammatory Bowel Diseases	2E-7	28067908

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000127838	rs10716631	2	218273447	G	High light scatter reticulocyte percentage of red cells	27863252	[0.024-0.039] unit decrease	0.0314017	EFO_0007986
ENSG00000127838	rs1870125	2	218323178	T	Monocyte count	27863252	[0.023-0.037] unit increase	0.03003961	EFO_0005091
ENSG00000127838	rs4791	2	218274217	T	Reticulocyte count	27863252	[0.023-0.037] unit decrease	0.02978423	EFO_0007986
ENSG00000127838	rs2382817	2	218286495	A	Ulcerative colitis	26192919	[1.05-1.1]	1.0740336	EFO_0000729
ENSG00000127838	rs2382817	2	218286495	A	Crohn's disease	26192919	[1.05-1.1]	1.0738211	EFO_0000384
ENSG00000127838	rs145013566	2	218297999	CA	Myeloid white cell count	27863252	[0.019-0.034] unit increase	0.02626699	EFO_0007988
ENSG00000127838	rs4791	2	218274217	T	Reticulocyte fraction of red cells	27863252	[0.024-0.039] unit decrease	0.03143097	EFO_0007986
ENSG00000127838	rs4674280	2	218276735	G	Red cell distribution width	27863252	[0.019-0.033] unit decrease	0.02622975	EFO_0005192
ENSG00000127838	rs145013566	2	218297999	CA	White blood cell count	27863252	[0.016-0.031] unit increase	0.02352016	EFO_0004308
ENSG00000127838	rs4791	2	218274217	T	High light scatter reticulocyte count	27863252	[0.022-0.036] unit decrease	0.0289765	EFO_0007986
ENSG00000127838	rs992157	2	218290058	A	Colorectal cancer	28960316	[1.08-1.16]	1.12	EFO_0005842
ENSG00000127838	rs2382817	2	218286495	?	Inflammatory bowel disease	28067908			EFO_0003767
ENSG00000127838	rs145013566	2	218297999	CA	Neutrophil count	27863252	[0.018-0.032] unit increase	0.02507077	EFO_0004833
ENSG00000127838	rs10716631	2	218273447	G	Plateletcrit	27863252	[0.016-0.031] unit decrease	0.02356192	EFO_0007985
ENSG00000127838	rs992157	2	218290058	A	Colorectal cancer	29917119	[1.04-1.09]	1.07	EFO_0005842
ENSG00000127838	rs2382817	2	218286495	A	Inflammatory bowel disease	23128233	[1.042-1.104]	1.073	EFO_0003767
ENSG00000127838	rs145013566	2	218297999	CA	Granulocyte count	27863252	[0.017-0.032] unit increase	0.02426803	EFO_0007987
ENSG00000127838	rs145013566	2	218297999	CA	Sum neutrophil eosinophil counts	27863252	[0.017-0.031] unit increase	0.02400607	EFO_0004833\|EFO_0004842
ENSG00000127838	rs145013566	2	218297999	CA	Sum basophil neutrophil counts	27863252	[0.018-0.033] unit increase	0.02523736	EFO_0004833\|EFO_0005090
ENSG00000127838	rs1877712	2	218303709	A	Red cell distribution width	28957414	[0.018-0.033] unit increase	0.0254583	EFO_0005192
ENSG00000127838	rs2382818	2	218291184	?	Heel bone mineral density	30048462	[0.008-0.0163] unit decrease	0.0121303	EFO_0009270
ENSG00000127838	rs1870123	2	218322975	A	Systolic blood pressure	30578418	[0.1-0.21] mmHg decrease	0.1532	EFO_0006335
ENSG00000127838	rs2292553	2	218282080	?	Gallstone disease	30504769	[1.03-1.08]	1.0526316	EFO_0004210
ENSG00000127838	rs897877	2	218328032	?	Waist-hip ratio	30595370			EFO_0004343
ENSG00000127838	rs2382818	2	218291184	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000127838	rs2271543	2	218277768	?	Cardiovascular disease	30595370			EFO_0000319

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000127838's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000127838	PNKD	94	62.745	ENSAPOG00000019072	pnkd	91	61.231	Acanthochromis_polyacanthus
ENSG00000127838	PNKD	100	95.065	ENSAMEG00000003089	PNKD	100	95.065	Ailuropoda_melanoleuca
ENSG00000127838	PNKD	94	62.092	ENSACIG00000015359	pnkd	96	54.570	Amphilophus_citrinellus
ENSG00000127838	PNKD	94	62.418	ENSAOCG00000011458	-	91	60.923	Amphiprion_ocellaris
ENSG00000127838	PNKD	86	59.790	ENSAOCG00000024159	pnkd	89	58.361	Amphiprion_ocellaris
ENSG00000127838	PNKD	94	62.418	ENSAPEG00000011710	pnkd	91	60.923	Amphiprion_percula
ENSG00000127838	PNKD	94	62.092	ENSATEG00000002727	pnkd	92	60.615	Anabas_testudineus
ENSG00000127838	PNKD	94	63.072	ENSACAG00000001617	PNKD	99	56.250	Anolis_carolinensis
ENSG00000127838	PNKD	100	98.961	ENSANAG00000019661	PNKD	100	99.057	Aotus_nancymaae
ENSG00000127838	PNKD	94	63.072	ENSACLG00000021665	pnkd	91	61.846	Astatotilapia_calliptera
ENSG00000127838	PNKD	95	63.344	ENSAMXG00000043305	pnkd	90	62.883	Astyanax_mexicanus
ENSG00000127838	PNKD	100	90.305	ENSBTAG00000003936	PNKD	100	91.136	Bos_taurus
ENSG00000127838	PNKD	100	98.769	ENSCJAG00000010820	PNKD	100	98.769	Callithrix_jacchus
ENSG00000127838	PNKD	100	92.987	ENSCAFG00000014632	PNKD	100	92.987	Canis_familiaris
ENSG00000127838	PNKD	100	91.967	ENSCAFG00020027093	PNKD	100	91.967	Canis_lupus_dingo
ENSG00000127838	PNKD	100	94.026	ENSCHIG00000002862	PNKD	100	94.026	Capra_hircus
ENSG00000127838	PNKD	100	97.143	ENSTSYG00000034863	PNKD	100	97.143	Carlito_syrichta
ENSG00000127838	PNKD	100	95.584	ENSCPOG00000020589	PNKD	100	95.584	Cavia_porcellus
ENSG00000127838	PNKD	100	99.221	ENSCCAG00000036713	PNKD	100	99.221	Cebus_capucinus
ENSG00000127838	PNKD	100	99.740	ENSCATG00000041188	PNKD	100	99.740	Cercocebus_atys
ENSG00000127838	PNKD	100	96.364	ENSCLAG00000012048	PNKD	100	96.364	Chinchilla_lanigera
ENSG00000127838	PNKD	100	99.740	ENSCSAG00000008892	PNKD	100	99.740	Chlorocebus_sabaeus
ENSG00000127838	PNKD	100	99.221	ENSCANG00000032283	PNKD	100	99.221	Colobus_angolensis_palliatus
ENSG00000127838	PNKD	100	96.104	ENSCGRG00001024071	Pnkd	100	96.104	Cricetulus_griseus_chok1gshd
ENSG00000127838	PNKD	100	91.967	ENSCGRG00000005443	Pnkd	97	96.000	Cricetulus_griseus_crigri
ENSG00000127838	PNKD	94	60.131	ENSCSEG00000013958	pnkd	89	59.561	Cynoglossus_semilaevis
ENSG00000127838	PNKD	93	63.787	ENSCVAG00000005723	pnkd	89	62.069	Cyprinodon_variegatus
ENSG00000127838	PNKD	95	61.736	ENSDARG00000071032	pnkd	89	61.875	Danio_rerio
ENSG00000127838	PNKD	100	91.136	ENSDNOG00000046154	PNKD	89	91.136	Dasypus_novemcinctus
ENSG00000127838	PNKD	100	96.124	ENSDORG00000016109	Pnkd	100	96.124	Dipodomys_ordii
ENSG00000127838	PNKD	94	74.839	ENSETEG00000014587	PNKD	100	65.296	Echinops_telfairi
ENSG00000127838	PNKD	93	53.821	ENSEBUG00000013857	pnkd	98	53.668	Eptatretus_burgeri
ENSG00000127838	PNKD	100	91.967	ENSEASG00005012391	PNKD	100	91.967	Equus_asinus_asinus
ENSG00000127838	PNKD	100	94.286	ENSECAG00000013322	PNKD	100	94.286	Equus_caballus
ENSG00000127838	PNKD	97	59.236	ENSELUG00000015007	pnkd	87	59.236	Esox_lucius
ENSG00000127838	PNKD	100	91.690	ENSFCAG00000002373	PNKD	100	92.521	Felis_catus
ENSG00000127838	PNKD	94	62.951	ENSFALG00000004028	PNKD	97	62.385	Ficedula_albicollis
ENSG00000127838	PNKD	100	96.364	ENSFDAG00000012326	PNKD	100	96.364	Fukomys_damarensis
ENSG00000127838	PNKD	94	62.745	ENSFHEG00000010999	pnkd	87	61.538	Fundulus_heteroclitus
ENSG00000127838	PNKD	94	60.784	ENSGMOG00000009565	pnkd	89	60.436	Gadus_morhua
ENSG00000127838	PNKD	94	62.623	ENSGALG00000022166	PNKD	99	62.701	Gallus_gallus
ENSG00000127838	PNKD	94	63.072	ENSGAFG00000013942	pnkd	80	62.382	Gambusia_affinis
ENSG00000127838	PNKD	94	61.765	ENSGACG00000007119	pnkd	91	61.468	Gasterosteus_aculeatus
ENSG00000127838	PNKD	94	62.418	ENSGAGG00000017234	PNKD	100	62.264	Gopherus_agassizii
ENSG00000127838	PNKD	100	100.000	ENSGGOG00000006892	PNKD	100	100.000	Gorilla_gorilla
ENSG00000127838	PNKD	94	63.072	ENSHBUG00000001234	pnkd	91	61.846	Haplochromis_burtoni
ENSG00000127838	PNKD	100	95.584	ENSHGLG00000013971	PNKD	100	95.584	Heterocephalus_glaber_female
ENSG00000127838	PNKD	100	95.584	ENSHGLG00100005225	PNKD	100	95.584	Heterocephalus_glaber_male
ENSG00000127838	PNKD	93	63.123	ENSHCOG00000018894	pnkd	89	61.562	Hippocampus_comes
ENSG00000127838	PNKD	97	62.776	ENSIPUG00000013907	pnkd	99	64.169	Ictalurus_punctatus
ENSG00000127838	PNKD	100	96.883	ENSSTOG00000024593	PNKD	100	96.883	Ictidomys_tridecemlineatus
ENSG00000127838	PNKD	100	94.545	ENSJJAG00000023559	Pnkd	100	95.584	Jaculus_jaculus
ENSG00000127838	PNKD	94	62.092	ENSKMAG00000014879	pnkd	89	61.442	Kryptolebias_marmoratus
ENSG00000127838	PNKD	94	62.418	ENSLBEG00000000985	pnkd	89	62.069	Labrus_bergylta
ENSG00000127838	PNKD	94	62.745	ENSLOCG00000000821	pnkd	89	62.069	Lepisosteus_oculatus
ENSG00000127838	PNKD	94	95.425	ENSLAFG00000007427	PNKD	100	84.670	Loxodonta_africana
ENSG00000127838	PNKD	100	99.740	ENSMFAG00000038281	PNKD	100	99.740	Macaca_fascicularis
ENSG00000127838	PNKD	56	100.000	ENSMMUG00000022819	-	100	100.000	Macaca_mulatta
ENSG00000127838	PNKD	100	99.169	ENSMNEG00000041541	PNKD	100	99.682	Macaca_nemestrina
ENSG00000127838	PNKD	100	99.740	ENSMLEG00000042812	PNKD	100	99.740	Mandrillus_leucophaeus
ENSG00000127838	PNKD	94	62.418	ENSMAMG00000017212	pnkd	89	61.755	Mastacembelus_armatus
ENSG00000127838	PNKD	91	62.712	ENSMZEG00005012514	pnkd	100	62.712	Maylandia_zebra
ENSG00000127838	PNKD	51	58.480	ENSMGAG00000011524	PNKD	100	55.804	Meleagris_gallopavo
ENSG00000127838	PNKD	100	91.413	ENSMAUG00000013099	Pnkd	100	91.967	Mesocricetus_auratus
ENSG00000127838	PNKD	100	96.364	ENSMICG00000042547	PNKD	100	96.364	Microcebus_murinus
ENSG00000127838	PNKD	100	94.301	ENSMOCG00000007956	Pnkd	100	95.855	Microtus_ochrogaster
ENSG00000127838	PNKD	95	62.581	ENSMMOG00000005679	pnkd	90	62.581	Mola_mola
ENSG00000127838	PNKD	95	79.870	ENSMODG00000015497	PNKD	87	80.064	Monodelphis_domestica
ENSG00000127838	PNKD	93	64.452	ENSMALG00000005967	pnkd	78	63.898	Monopterus_albus
ENSG00000127838	PNKD	100	95.844	MGP_CAROLIEiJ_G0014258	Pnkd	100	95.844	Mus_caroli
ENSG00000127838	PNKD	100	96.104	ENSMUSG00000026179	Pnkd	100	96.104	Mus_musculus
ENSG00000127838	PNKD	100	96.104	MGP_PahariEiJ_G0027496	Pnkd	100	96.104	Mus_pahari
ENSG00000127838	PNKD	100	96.104	MGP_SPRETEiJ_G0015064	Pnkd	100	96.104	Mus_spretus
ENSG00000127838	PNKD	100	92.244	ENSMPUG00000016531	PNKD	100	93.352	Mustela_putorius_furo
ENSG00000127838	PNKD	94	94.444	ENSMLUG00000004125	PNKD	100	94.444	Myotis_lucifugus
ENSG00000127838	PNKD	100	96.104	ENSNGAG00000014980	Pnkd	100	96.104	Nannospalax_galili
ENSG00000127838	PNKD	94	63.072	ENSNBRG00000020031	pnkd	96	62.460	Neolamprologus_brichardi
ENSG00000127838	PNKD	98	77.358	ENSMEUG00000011266	PNKD	100	73.247	Notamacropus_eugenii
ENSG00000127838	PNKD	100	93.352	ENSODEG00000009734	PNKD	100	93.906	Octodon_degus
ENSG00000127838	PNKD	94	62.418	ENSONIG00000004389	pnkd	91	61.231	Oreochromis_niloticus
ENSG00000127838	PNKD	94	95.425	ENSOCUG00000023754	PNKD	100	84.670	Oryctolagus_cuniculus
ENSG00000127838	PNKD	93	61.589	ENSORLG00000026276	pnkd	92	59.517	Oryzias_latipes
ENSG00000127838	PNKD	93	61.589	ENSORLG00020008373	pnkd	97	61.589	Oryzias_latipes_hni
ENSG00000127838	PNKD	94	60.784	ENSORLG00015005276	pnkd	92	59.819	Oryzias_latipes_hsok
ENSG00000127838	PNKD	99	57.423	ENSOMEG00000016106	pnkd	89	61.059	Oryzias_melastigma
ENSG00000127838	PNKD	94	97.059	ENSOGAG00000001792	PNKD	100	97.059	Otolemur_garnettii
ENSG00000127838	PNKD	100	94.286	ENSOARG00000019505	PNKD	100	94.286	Ovis_aries
ENSG00000127838	PNKD	100	100.000	ENSPPAG00000034969	PNKD	100	100.000	Pan_paniscus
ENSG00000127838	PNKD	100	91.690	ENSPPRG00000023720	PNKD	100	92.798	Panthera_pardus
ENSG00000127838	PNKD	100	88.571	ENSPTIG00000021040	PNKD	100	88.571	Panthera_tigris_altaica
ENSG00000127838	PNKD	100	99.740	ENSPTRG00000012914	PNKD	100	99.740	Pan_troglodytes
ENSG00000127838	PNKD	100	99.740	ENSPANG00000005752	PNKD	100	99.740	Papio_anubis
ENSG00000127838	PNKD	94	60.784	ENSPKIG00000011208	pnkd	100	60.377	Paramormyrops_kingsleyae
ENSG00000127838	PNKD	94	59.804	ENSPMGG00000005169	pnkd	100	59.804	Periophthalmus_magnuspinnatus
ENSG00000127838	PNKD	100	96.104	ENSPEMG00000010689	Pnkd	100	96.104	Peromyscus_maniculatus_bairdii
ENSG00000127838	PNKD	94	54.723	ENSPMAG00000006947	pnkd	99	54.723	Petromyzon_marinus
ENSG00000127838	PNKD	94	80.392	ENSPCIG00000021457	PNKD	100	75.482	Phascolarctos_cinereus
ENSG00000127838	PNKD	93	63.907	ENSPFOG00000010628	pnkd	89	62.617	Poecilia_formosa
ENSG00000127838	PNKD	65	68.246	ENSPLAG00000020583	pnkd	87	66.087	Poecilia_latipinna
ENSG00000127838	PNKD	93	55.590	ENSPMEG00000006542	pnkd	87	54.839	Poecilia_mexicana
ENSG00000127838	PNKD	93	62.914	ENSPREG00000014434	pnkd	89	61.682	Poecilia_reticulata
ENSG00000127838	PNKD	100	99.481	ENSPPYG00000013167	PNKD	100	99.481	Pongo_abelii
ENSG00000127838	PNKD	100	76.364	ENSPCAG00000003946	PNKD	100	76.364	Procavia_capensis
ENSG00000127838	PNKD	100	97.143	ENSPCOG00000019839	PNKD	100	97.143	Propithecus_coquereli
ENSG00000127838	PNKD	94	63.072	ENSPNYG00000016327	pnkd	100	62.579	Pundamilia_nyererei
ENSG00000127838	PNKD	100	59.669	ENSPNAG00000008655	pnkd	90	63.497	Pygocentrus_nattereri
ENSG00000127838	PNKD	100	95.844	ENSRNOG00000014806	Pnkd	100	95.844	Rattus_norvegicus
ENSG00000127838	PNKD	100	99.740	ENSRBIG00000031614	PNKD	100	99.740	Rhinopithecus_bieti
ENSG00000127838	PNKD	100	99.740	ENSRROG00000045542	PNKD	100	99.740	Rhinopithecus_roxellana
ENSG00000127838	PNKD	100	98.769	ENSSBOG00000036000	PNKD	100	98.769	Saimiri_boliviensis_boliviensis
ENSG00000127838	PNKD	94	80.259	ENSSHAG00000016339	PNKD	100	80.374	Sarcophilus_harrisii
ENSG00000127838	PNKD	94	63.725	ENSSFOG00015013028	pnkd	90	61.905	Scleropages_formosus
ENSG00000127838	PNKD	94	62.745	ENSSMAG00000006812	pnkd	91	61.538	Scophthalmus_maximus
ENSG00000127838	PNKD	94	61.765	ENSSDUG00000012538	pnkd	91	60.615	Seriola_dumerili
ENSG00000127838	PNKD	94	61.765	ENSSLDG00000021431	pnkd	88	60.615	Seriola_lalandi_dorsalis
ENSG00000127838	PNKD	94	52.614	ENSSPUG00000018454	PNKD	98	52.614	Sphenodon_punctatus
ENSG00000127838	PNKD	94	62.418	ENSSPAG00000007083	pnkd	91	60.923	Stegastes_partitus
ENSG00000127838	PNKD	100	95.325	ENSSSCG00000029002	PNKD	100	95.860	Sus_scrofa
ENSG00000127838	PNKD	94	60.458	ENSTRUG00000009399	pnkd	89	60.188	Takifugu_rubripes
ENSG00000127838	PNKD	94	60.784	ENSTNIG00000010992	pnkd	90	60.436	Tetraodon_nigroviridis
ENSG00000127838	PNKD	100	93.506	ENSTTRG00000012895	PNKD	100	93.506	Tursiops_truncatus
ENSG00000127838	PNKD	100	91.690	ENSUAMG00000000289	PNKD	100	91.690	Ursus_americanus
ENSG00000127838	PNKD	100	79.221	ENSUMAG00000019639	PNKD	100	79.221	Ursus_maritimus
ENSG00000127838	PNKD	100	95.238	ENSVVUG00000007348	PNKD	100	95.065	Vulpes_vulpes
ENSG00000127838	PNKD	94	65.033	ENSXETG00000014931	pnkd	99	64.309	Xenopus_tropicalis
ENSG00000127838	PNKD	96	61.783	ENSXCOG00000014370	pnkd	97	61.783	Xiphophorus_couchianus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004416	hydroxyacylglutathione hydrolase activity	-	IEA	Function
GO:0005515	protein binding	25066297.25416956.25910212.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005739	mitochondrion	-	IDA	Component
GO:0016020	membrane	22214848.	IDA	Component
GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	-	IEA	Process
GO:0032225	regulation of synaptic transmission, dopaminergic	-	IEA	Process
GO:0042053	regulation of dopamine metabolic process	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0046929	negative regulation of neurotransmitter secretion	25730884.	IMP	Process
GO:0050884	neuromuscular process controlling posture	-	IEA	Process

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.