Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
LIHC | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
OV | |||||||
OV | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
PCPG | |||
THCA | |||
THYM |
Cancer | P-value | Q-value |
---|---|---|
SARC | ||
MESO | ||
SKCM | ||
PCPG | ||
CESC | ||
UCEC | ||
DLBC | ||
CHOL | ||
UVM | ||
OV |
Protein ID | Domain | Pfam ID | E-value | Domain number | Total number |
---|---|---|---|---|---|
ENSP00000249116 | APOBEC_N | PF08210.11 | 5e-47 | 1 | 1 |
ENSP00000384359 | APOBEC_N | PF08210.11 | 5e-47 | 1 | 1 |
ENSP00000481904 | APOBEC_N | PF08210.11 | 5e-47 | 1 | 1 |
ENSP00000249116 | APOBEC_C | PF05240.14 | 3.9e-30 | 1 | 1 |
ENSP00000384359 | APOBEC_C | PF05240.14 | 3.9e-30 | 1 | 1 |
ENSP00000481904 | APOBEC_C | PF05240.14 | 3.9e-30 | 1 | 1 |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000402255 | APOBEC3A-202 | 1478 | - | ENSP00000384359 | 199 (aa) | - | P31941 |
ENST00000249116 | APOBEC3A-201 | 1444 | - | ENSP00000249116 | 199 (aa) | - | P31941 |
ENST00000495988 | APOBEC3A-204 | 566 | - | - | - (aa) | - | - |
ENST00000618553 | APOBEC3A-205 | 1103 | - | ENSP00000481904 | 199 (aa) | - | P31941 |
ENST00000488758 | APOBEC3A-203 | 344 | - | - | - (aa) | - | - |
Pathway ID | Pathway Name | Source |
---|---|---|
hsa05170 | Human immunodeficiency virus 1 infection | KEGG |
ensgID | Trait | pValue | Pubmed ID |
---|---|---|---|
ENSG00000128383 | Breast Neoplasms | 4E-6 | 27354352 |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000128383 | rs12628403 | 22 | 38962032 | C | Breast cancer | 27354352 | [1.09-1.25] | 1.17 | EFO_0000305 |
ENSG00000128383 | rs12628403 | 22 | 38962032 | ? | Mean corpuscular hemoglobin | 30595370 | EFO_0004527 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000128383 | APOBEC3A | 96 | 56.701 | ENSCJAG00000012500 | - | 96 | 56.701 | Callithrix_jacchus |
ENSG00000128383 | APOBEC3A | 100 | 56.931 | ENSTSYG00000035593 | - | 100 | 56.931 | Carlito_syrichta |
ENSG00000128383 | APOBEC3A | 95 | 67.876 | ENSCCAG00000027450 | - | 96 | 67.876 | Cebus_capucinus |
ENSG00000128383 | APOBEC3A | 100 | 81.683 | ENSCATG00000013527 | - | 100 | 81.683 | Cercocebus_atys |
ENSG00000128383 | APOBEC3A | 95 | 79.365 | ENSCSAG00000006445 | - | 76 | 79.365 | Chlorocebus_sabaeus |
ENSG00000128383 | APOBEC3A | 72 | 76.871 | ENSCSAG00000018401 | - | 70 | 76.871 | Chlorocebus_sabaeus |
ENSG00000128383 | APOBEC3A | 100 | 83.417 | ENSCANG00000030513 | - | 100 | 83.417 | Colobus_angolensis_palliatus |
ENSG00000128383 | APOBEC3A | 96 | 87.047 | ENSGGOG00000006721 | APOBEC3B | 98 | 87.047 | Gorilla_gorilla |
ENSG00000128383 | APOBEC3A | 100 | 80.693 | ENSMFAG00000008980 | APOBEC3A | 100 | 80.693 | Macaca_fascicularis |
ENSG00000128383 | APOBEC3A | 95 | 83.854 | ENSMMUG00000004015 | - | 98 | 83.854 | Macaca_mulatta |
ENSG00000128383 | APOBEC3A | 100 | 81.188 | ENSMMUG00000042504 | APOBEC3A | 100 | 81.188 | Macaca_mulatta |
ENSG00000128383 | APOBEC3A | 95 | 76.596 | ENSMNEG00000043211 | - | 93 | 76.596 | Macaca_nemestrina |
ENSG00000128383 | APOBEC3A | 96 | 80.311 | ENSMLEG00000004809 | - | 98 | 80.311 | Mandrillus_leucophaeus |
ENSG00000128383 | APOBEC3A | 100 | 90.955 | ENSNLEG00000015215 | - | 100 | 90.955 | Nomascus_leucogenys |
ENSG00000128383 | APOBEC3A | 96 | 90.674 | ENSPPAG00000009288 | APOBEC3B | 98 | 90.674 | Pan_paniscus |
ENSG00000128383 | APOBEC3A | 99 | 95.960 | ENSPTRG00000014384 | APOBEC3B | 99 | 95.960 | Pan_troglodytes |
ENSG00000128383 | APOBEC3A | 100 | 79.703 | ENSPANG00000006941 | APOBEC3B | 100 | 79.703 | Papio_anubis |
ENSG00000128383 | APOBEC3A | 96 | 83.420 | ENSPPYG00000011831 | - | 98 | 83.420 | Pongo_abelii |
ENSG00000128383 | APOBEC3A | 77 | 59.615 | ENSPCOG00000017606 | - | 98 | 59.615 | Propithecus_coquereli |
ENSG00000128383 | APOBEC3A | 100 | 82.915 | ENSRBIG00000042829 | - | 100 | 85.027 | Rhinopithecus_bieti |
ENSG00000128383 | APOBEC3A | 100 | 82.915 | ENSRROG00000028773 | APOBEC3G | 100 | 85.027 | Rhinopithecus_roxellana |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0003723 | RNA binding | 21873635. | IBA | Function |
GO:0004126 | cytidine deaminase activity | 21873635. | IBA | Function |
GO:0004126 | cytidine deaminase activity | 16527742.21123384. | IDA | Function |
GO:0004126 | cytidine deaminase activity | 20062055. | IMP | Function |
GO:0005515 | protein binding | 22915799.24557838. | IPI | Function |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0005634 | nucleus | 16527742.21123384.21835787. | IDA | Component |
GO:0005737 | cytoplasm | 21873635. | IBA | Component |
GO:0005737 | cytoplasm | 16527742.21123384.21835787. | IDA | Component |
GO:0008270 | zinc ion binding | - | IEA | Function |
GO:0009972 | cytidine deamination | - | IEA | Process |
GO:0010529 | negative regulation of transposition | 16527742.20062055.21123384. | IDA | Process |
GO:0016554 | cytidine to uridine editing | 21873635. | IBA | Process |
GO:0044356 | clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine | 20062055. | IDA | Process |
GO:0045071 | negative regulation of viral genome replication | 16527742. | IDA | Process |
GO:0045087 | innate immune response | 21123384. | IDA | Process |
GO:0047844 | deoxycytidine deaminase activity | 22457529. | IMP | Function |
GO:0051607 | defense response to virus | 21123384.22457529. | IDA | Process |
GO:0070383 | DNA cytosine deamination | 16527742.21123384. | IDA | Process |
GO:0070383 | DNA cytosine deamination | 20062055. | IMP | Process |
GO:0071466 | cellular response to xenobiotic stimulus | 20062055. | IDA | Process |
GO:0080111 | DNA demethylation | 21873635. | IBA | Process |
GO:0080111 | DNA demethylation | 21496894. | IDA | Process |