EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29395313	Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.	Gynecol Oncol	2018 Apr	Zhang HR	doi: 10.1016/j.ygyno.2018.01.024
25421751	Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC.	Mol Cancer Res	2015 Apr	Ohmura G	doi: 10.1158/1541-7786.MCR-14-0410
26545583	MicroRNA-363 targets myosin 1B to reduce cellular migration in head and neck cancer.	BMC Cancer	2015 Nov 6	Chapman BV	doi: 10.1186/s12885-015-1888-3.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr2	191387463	Intron	novel		0.14
BLCA	chr2	191392188	Missense_Mutation	NA	R688P	0.22
BLCA	chr2	191423837	Splice_Region	rs772361283	E1096E	0.42
BLCA	chr2	191387466	Intron	novel		0.38
BLCA	chr2	191390441	Missense_Mutation	novel	R644T	0.22
BLCA	chr2	191423878	Missense_Mutation	novel	F1110C	0.78
BLCA	chr2	191390493	Splice_Site	rs757926686	X661_splice	0.46
BLCA	chr2	191411117	Nonsense_Mutation	novel	E940*	0.13
BLCA	chr2	191363815	Missense_Mutation	novel	E285K	0.29
BLCA	chr2	191360630	Splice_Site	novel	X188_splice	0.5
BLCA	chr2	191387269	Missense_Mutation	novel	L534V	0.38
BLCA	chr2	191409062	Missense_Mutation	novel	E884K	0.21
BLCA	chr2	191387488	Intron	novel		0.36
BLCA	chr2	191330021	Missense_Mutation	novel	G113E	0.11
BLCA	chr2	191411166	Missense_Mutation	NA	P956L	0.19
BLCA	chr2	191330030	Splice_Site	NA	X116_splice	0.43
BRCA	chr2	191381232	Intron	novel		0.33
BRCA	chr2	191387419	Missense_Mutation	NA	N584D	0.23
BRCA	chr2	191329978	Missense_Mutation	novel	D99N	0.03
BRCA	chr2	191381221	Intron	novel		0.41
BRCA	chr2	191387608	Intron	novel		0.08
BRCA	chr2	191385936	Missense_Mutation	NA	T469K	0.15
BRCA	chr2	191330010	Splice_Site	novel	X110_splice	0.04
BRCA	chr2	191393085	Missense_Mutation	NA	E697K	0.14
BRCA	chr2	191360691	Missense_Mutation	NA	F208C	0.21
BRCA	chr2	191414047	Splice_Site	novel	X958_splice	0.08
BRCA	chr2	191423986	3'UTR	novel		0.32
BRCA	chr2	191387462	Intron	novel		0.1
CESC	chr2	191393212	Missense_Mutation	novel	R739M	0.24
CESC	chr2	191329998	Frame_Shift_Ins	novel	*I106Yfs14**	0.04
CESC	chr2	191329999	Frame_Shift_Ins	novel	*T107Nfs59**	0.04
CESC	chr2	191381564	Missense_Mutation	NA	E430K	0.54
CESC	chr2	191390406	Silent	rs371321877	Y632Y	0.3
CESC	chr2	191402652	Silent	rs770052311	R830R	0.09
CESC	chr2	191362323	Silent	rs761999972	S239S	0.83
CESC	chr2	191276988	Silent	novel	F31F	0.22
CESC	chr2	191402628	Splice_Region	novel		0.37
COAD	chr2	191390310	Frame_Shift_Ins	NA	*A603Sfs37**	0.42
COAD	chr2	191364224	Missense_Mutation	rs762103792	R327Q	0.19
COAD	chr2	191364209	Missense_Mutation	rs749571664	R322Q	0.34
COAD	chr2	191370288	Missense_Mutation	novel	F394S	0.36
COAD	chr2	191385953	Missense_Mutation	novel	F475V	0.17
COAD	chr2	191396472	Missense_Mutation	novel	I757S	0.25
COAD	chr2	191393178	Frame_Shift_Del	NA	*S730Afs4**	0.38
COAD	chr2	191381500	Silent	rs147109563	N408N	0.32
COAD	chr2	191387619	Intron	novel		0.14
COAD	chr2	191416224	Missense_Mutation	rs769052951	N1090S	0.24
COAD	chr2	191364168	Silent	NA	E308E	0.43
COAD	chr2	191392187	Nonsense_Mutation	novel	R688*	0.39
COAD	chr2	191390399	Missense_Mutation	NA	A630V	0.35
COAD	chr2	191411140	Frame_Shift_Ins	NA	*F948Cfs47**	0.41
COAD	chr2	191329949	Missense_Mutation	NA	D89G	0.41
COAD	chr2	191392177	Missense_Mutation	NA	K684N	0.17
COAD	chr2	191408134	Missense_Mutation	novel	K859R	0.1
COAD	chr2	191277003	Silent	novel	K36K	0.4
COAD	chr2	191381248	Intron	novel		0.42
COAD	chr2	191369608	Nonsense_Mutation	NA	R367*	0.39
COAD	chr2	191393178	Frame_Shift_Del	NA	*S730Afs4**	0.42
COAD	chr2	191424327	3'UTR	novel		0.27
COAD	chr2	191341562	Missense_Mutation	novel	E150K	0.05
COAD	chr2	191393089	Missense_Mutation	novel	D698G	0.08
ESCA	chr2	191414552	Silent	novel	N1014N	0.17
ESCA	chr2	191402635	Nonsense_Mutation	rs777573572	R825*	0.09
ESCA	chr2	191416231	Missense_Mutation	novel	E1092D	0.41
GBM	chr2	191423887	Missense_Mutation	novel	G1113E	0.2
GBM	chr2	191276917	Missense_Mutation	novel	T8S	0.31
GBM	chr2	191396462	Missense_Mutation	NA	A754T	0.43
GBM	chr2	191400415	Missense_Mutation	NA	K777E	0.31
GBM	chr2	191383341	Missense_Mutation	NA	N451I	0.43
GBM	chr2	191423966	3'UTR	rs748786968		0.16
GBM	chr2	191411066	Missense_Mutation	NA	C923R	0.36
GBM	chr2	191414077	Missense_Mutation	NA	L968P	0.3
GBM	chr2	191363842	Missense_Mutation	novel	G294S	0.28
GBM	chr2	191383291	Nonsense_Mutation	novel	W434*	0.2
GBM	chr2	191364216	Missense_Mutation	novel	F324L	0.09
GBM	chr2	191390377	Nonsense_Mutation	novel	E623*	0.4
GBM	chr2	191363866	Missense_Mutation	novel	D302N	0.18
GBM	chr2	191362305	Missense_Mutation	novel	N233K	0.04
GBM	chr2	191393089	Missense_Mutation	novel	D698V	0.05
GBM	chr2	191424049	3'UTR	novel		0.15
HNSC	chr2	191385919	Missense_Mutation	novel	E463D	0.33
HNSC	chr2	191386032	Missense_Mutation	rs199738105	N501S	0.07
HNSC	chr2	191364222	Silent	rs532881047	F326F	0.21
HNSC	chr2	191409160	Missense_Mutation	novel	R916S	0.19
HNSC	chr2	191414153	Silent	novel	V993V	0.27
HNSC	chr2	191360696	Nonsense_Mutation	novel	Q210*	0.13
HNSC	chr2	191423982	3'UTR	novel		0.21
HNSC	chr2	191385993	Missense_Mutation	novel	H488R	0.22
KIRC	chr2	191350174	Missense_Mutation	NA	D171Y	0.18
KIRC	chr2	191276967	Silent	NA	E24E	0.14
KIRC	chr2	191424015	3'UTR	novel		0.34
KIRC	chr2	191364197	Nonsense_Mutation	NA	S318*	0.2
KIRP	chr2	191341503	Frame_Shift_Ins	novel	*G132Rfs5**	0.41
KIRP	chr2	191362281	Silent	novel	L225L	0.38
KIRP	chr2	191329963	Missense_Mutation	rs773275389	S94A	0.07
LAML	chr2	191364194	Missense_Mutation	novel	Q317R	0.1
LAML	chr2	191363785	Missense_Mutation	novel	V275M	0.05
LAML	chr2	191385934	Silent	novel	G468G	0.08
LGG	chr2	191350219	Missense_Mutation	novel	S186R	0.27
LGG	chr2	191387223	Splice_Site	novel	X519_splice	0.35
LIHC	chr2	191424001	3'UTR	rs760588702		0.14
LIHC	chr2	191296214	Missense_Mutation	NA	L80R	0.25
LIHC	chr2	191363726	Splice_Site	NA	X256_splice	0.3
LIHC	chr2	191400750	Missense_Mutation	rs765571133	A795V	0.06
LIHC	chr2	191409159	Missense_Mutation	NA	R916T	0.49
LUAD	chr2	191329971	Silent	novel	R96R	0.09
LUAD	chr2	191390389	Missense_Mutation	novel	V627L	0.22
LUAD	chr2	191396449	Silent	NA	Q749Q	0.15
LUAD	chr2	191393112	Missense_Mutation	NA	D706Y	0.19
LUAD	chr2	191414063	Missense_Mutation	NA	F963L	0.16
LUAD	chr2	191409047	Nonsense_Mutation	novel	Q879*	0.15
LUAD	chr2	191387334	Silent	rs768956007	P555P	0.24
LUAD	chr2	191414592	Missense_Mutation	novel	E1028Q	0.09
LUAD	chr2	191296151	Missense_Mutation	novel	R59L	0.52
LUAD	chr2	191423899	Missense_Mutation	NA	N1117T	0.13
LUAD	chr2	191393099	Missense_Mutation	NA	K701N	0.13
LUAD	chr2	191385993	Missense_Mutation	novel	H488R	0.18
LUAD	chr2	191423859	Missense_Mutation	NA	D1104Y	0.3
LUAD	chr2	191360706	Missense_Mutation	NA	S213C	0.46
LUSC	chr2	191383295	Missense_Mutation	NA	H436Y	0.25
LUSC	chr2	191390335	Missense_Mutation	novel	E609K	0.07
LUSC	chr2	191369575	Missense_Mutation	novel	L356F	0.09
LUSC	chr2	191386032	Missense_Mutation	novel	N501T	0.03
LUSC	chr2	191385945	Missense_Mutation	novel	D472G	0.45
LUSC	chr2	191385983	Missense_Mutation	novel	T485A	0.4
LUSC	chr2	191360658	Missense_Mutation	novel	K197I	0.65
LUSC	chr2	191363842	Missense_Mutation	novel	G294C	0.43
LUSC	chr2	191329999	Missense_Mutation	rs763303993	I106V	0.07
LUSC	chr2	191411133	Missense_Mutation	novel	S945I	0.8
LUSC	chr2	191329969	Missense_Mutation	novel	R96G	0.14
LUSC	chr2	191341501	Silent	rs538116520	C129C	0.09
LUSC	chr2	191362272	Silent	rs770519095	K222K	0.37
LUSC	chr2	191381454	Splice_Region	novel		0.17
LUSC	chr2	191381563	Silent	novel	R429R	0.29
LUSC	chr2	191387248	Missense_Mutation	novel	V527F	0.46
OV	chr2	191396494	Missense_Mutation	NA	W764C	0.41
OV	chr2	191387464	Intron	novel		0.65
OV	chr2	191416147	Silent	novel	L1064L	0.07
OV	chr2	191423967	3'UTR	rs11261		0.14
OV	chr2	191363845	Missense_Mutation	NA	L295I	0.36
OV	chr2	191390387	In_Frame_Ins	novel	R626_V627insNKPQGCEYIIV	0.03
OV	chr2	191402701	Missense_Mutation	NA	Y847N	0.43
OV	chr2	191411081	In_Frame_Del	novel	F930_Q933del	0.05
OV	chr2	191416220	Missense_Mutation	novel	L1089V	0.04
PAAD	chr2	191396452	Silent	novel	T750T	0.03
PAAD	chr2	191360646	Missense_Mutation	novel	S193Y	0.05
PAAD	chr2	191369608	Nonsense_Mutation	NA	R367*	0.1
PAAD	chr2	191402694	Missense_Mutation	novel	I844M	0.35
PRAD	chr2	191360662	Silent	novel	Q198Q	0.35
PRAD	chr2	191396486	Missense_Mutation	rs546152958	R762W	0.35
READ	chr2	191408185	Missense_Mutation	novel	R876I	0.11
READ	chr2	191416145	Missense_Mutation	NA	L1064I	0.24
READ	chr2	191424073	3'UTR	novel		0.24
READ	chr2	191296125	Silent	novel	S50S	0.07
READ	chr2	191423961	3'UTR	novel		0.4
READ	chr2	191350186	Missense_Mutation	novel	D175Y	0.37
READ	chr2	191369608	Nonsense_Mutation	NA	R367*	0.13
READ	chr2	191363833	Nonsense_Mutation	novel	R291*	0.47
READ	chr2	191381353	Intron	novel		0.3
READ	chr2	191393172	Missense_Mutation	novel	L726I	0.42
READ	chr2	191400385	Nonsense_Mutation	novel	R767*	0.41
SARC	chr2	191414620	Missense_Mutation	novel	V1037A	0.18
SARC	chr2	191400753	Missense_Mutation	rs758864271	R796Q	0.27
SKCM	chr2	191385881	Splice_Region	novel		0.32
SKCM	chr2	191416147	Silent	novel	L1064L	0.46
SKCM	chr2	191363748	Silent	novel	G262G	0.23
SKCM	chr2	191330019	Silent	NA	A112A	0.22
SKCM	chr2	191393189	Silent	novel	Q731Q	0.62
SKCM	chr2	191360648	Missense_Mutation	rs771551697	R194W	0.04
SKCM	chr2	191424030	3'UTR	novel		0.36
SKCM	chr2	191424102	3'UTR	novel		0.21
SKCM	chr2	191360720	Missense_Mutation	NA	E218K	0.06
SKCM	chr2	191346279	Silent	novel	R165R	0.21
SKCM	chr2	191390318	Missense_Mutation	novel	A603V	0.25
SKCM	chr2	191414529	Frame_Shift_Ins	novel	*L1009Pfs6**	0.14
SKCM	chr2	191409084	Missense_Mutation	NA	S891F	0.38
SKCM	chr2	191387517	Intron	novel		0.69
SKCM	chr2	191383337	Missense_Mutation	NA	E450K	0.54
SKCM	chr2	191416199	Missense_Mutation	novel	L1082F	0.38
SKCM	chr2	191387232	Silent	NA	Y521Y	0.3
SKCM	chr2	191364166	Missense_Mutation	novel	E308K	0.15
SKCM	chr2	191381554	Silent	novel	E426E	0.17
SKCM	chr2	191341548	Missense_Mutation	NA	S145F	0.3
SKCM	chr2	191387292	Silent	NA	A541A	0.32
SKCM	chr2	191276918	Missense_Mutation	NA	T8I	0.54
SKCM	chr2	191329966	Silent	novel	L95L	0.44
SKCM	chr2	191386027	Silent	novel	F499F	0.2
SKCM	chr2	191387316	Silent	NA	L549L	0.08
SKCM	chr2	191408138	Silent	NA	F860F	0.12
SKCM	chr2	191329965	Silent	NA	S94S	0.51
STAD	chr2	191329977	Missense_Mutation	novel	Q98H	0.05
STAD	chr2	191423965	3'UTR	rs374677707		0.24
STAD	chr2	191364183	Silent	rs376505594	T313T	0.1
STAD	chr2	191330014	Nonsense_Mutation	NA	G111*	0.24
STAD	chr2	191276977	Missense_Mutation	NA	E28K	0.08
STAD	chr2	191390339	Missense_Mutation	NA	A610V	0.12
STAD	chr2	191390301	Missense_Mutation	NA	K597N	0.07
STAD	chr2	191387453	Splice_Region	novel		0.19
STAD	chr2	191381534	Missense_Mutation	novel	L420I	0.28
STAD	chr2	191400396	Silent	NA	L770L	0.16
STAD	chr2	191362369	Missense_Mutation	rs139382265	R255W	0.32
STAD	chr2	191387499	Intron	novel		0.21
STAD	chr2	191400397	Missense_Mutation	rs200675888	R771W	0.32
STAD	chr2	191364161	Frame_Shift_Ins	novel	*E308Rfs4**	0.18
STAD	chr2	191393157	Missense_Mutation	rs147751540	R721C	0.16
STAD	chr2	191393178	Frame_Shift_Del	NA	*S730Afs4**	0.12
THCA	chr2	191369613	Silent	NA	I368I	0.05
UCEC	chr2	191296176	Missense_Mutation	novel	E67D	0.04
UCEC	chr2	191381362	Intron	novel		0.3
UCEC	chr2	191369548	Missense_Mutation	novel	Y347D	0.06
UCEC	chr2	191402488	Intron	novel		0.36
UCEC	chr2	191424112	3'UTR	novel		0.35
UCEC	chr2	191386057	Silent	novel	C509C	0.43
UCEC	chr2	191329978	Missense_Mutation	novel	D99Y	0.09
UCEC	chr2	191369609	Missense_Mutation	rs780531601	R367Q	0.36
UCEC	chr2	191411119	Missense_Mutation	NA	E940D	0.39
UCEC	chr2	191364208	Nonsense_Mutation	rs200446624	R322*	0.51
UCEC	chr2	191387535	Intron	novel		0.59
UCEC	chr2	191402481	Intron	novel		0.5
UCEC	chr2	191277007	Missense_Mutation	rs376294235	R38C	0.38
UCEC	chr2	191408164	Missense_Mutation	novel	I869S	0.4
UCEC	chr2	191390471	Missense_Mutation	NA	P654L	0.24
UCEC	chr2	191383278	Splice_Site	NA	X431_splice	0.49
UCEC	chr2	191423894	Frame_Shift_Ins	novel	*N1117Kfs8**	0.45
UCEC	chr2	191360676	Missense_Mutation	NA	R203I	0.26
UCEC	chr2	191296123	Missense_Mutation	NA	S50G	0.35
UCEC	chr2	191363793	Silent	NA	A277A	0.29
UCEC	chr2	191390409	Silent	NA	A633A	0.28
UCEC	chr2	191425000	3'UTR	novel		0.43
UCEC	chr2	191387306	Missense_Mutation	NA	S546N	0.31
UCEC	chr2	191423965	3'UTR	rs374677707		0.38
UCEC	chr2	191276919	Silent	novel	T8T	0.37
UCEC	chr2	191276916	Missense_Mutation	novel	K7N	0.12
UCEC	chr2	191364166	Nonsense_Mutation	novel	E308*	0.33
UCEC	chr2	191296144	Missense_Mutation	novel	P57T	0.43
UCEC	chr2	191393212	Missense_Mutation	novel	R739M	0.26
UCEC	chr2	191369555	Missense_Mutation	NA	R349P	0.31
UCEC	chr2	191362365	Silent	rs780334989	T253T	0.33
UCEC	chr2	191392147	Silent	rs142551317	P674P	0.44
UCEC	chr2	191393142	Missense_Mutation	rs539821767	R716W	0.45
UCEC	chr2	191423922	Nonsense_Mutation	novel	R1125*	0.4
UCEC	chr2	191424745	3'UTR	novel		0.26
UCEC	chr2	191402510	Intron	novel		0.27
UCEC	chr2	191416114	Splice_Site	novel	X1054_splice	0.43
UCEC	chr2	191362356	Missense_Mutation	novel	N250K	0.54
UCEC	chr2	191402707	Missense_Mutation	novel	L849F	0.44
UCEC	chr2	191329966	Missense_Mutation	novel	L95I	0.2
UCEC	chr2	191390392	Missense_Mutation	NA	R628W	0.38
UCEC	chr2	191423965	3'UTR	rs374677707		0.36
UCEC	chr2	191381259	Intron	novel		0.35
UCEC	chr2	191393167	Missense_Mutation	novel	F724S	0.23
UCEC	chr2	191402436	Intron	novel		0.4
UCEC	chr2	191386031	Missense_Mutation	NA	N501D	0.28
UCEC	chr2	191360646	Missense_Mutation	novel	S193Y	0.15
UCEC	chr2	191364202	Silent	novel	L320L	0.28
UCEC	chr2	191409052	Silent	novel	K880K	0.33
UCEC	chr2	191424105	3'UTR	novel		0.15
UCEC	chr2	191396486	Missense_Mutation	rs546152958	R762W	0.46
UCEC	chr2	191425025	3'UTR	novel		0.25
UCEC	chr2	191424150	3'UTR	novel		0.31
UCEC	chr2	191364224	Missense_Mutation	rs762103792	R327Q	0.5
UCEC	chr2	191369608	Nonsense_Mutation	NA	R367*	0.41
UCEC	chr2	191402628	Splice_Region	novel		0.4
UCEC	chr2	191408165	Silent	novel	I869I	0.39
UCEC	chr2	191414521	Missense_Mutation	novel	T1004K	0.08
UCEC	chr2	191329978	Missense_Mutation	novel	D99Y	0.16
UCEC	chr2	191381430	Intron	novel		0.11
UCEC	chr2	191411174	Splice_Site	novel	X958_splice	0.15
UCEC	chr2	191387403	Silent	novel	V578V	0.31
UCEC	chr2	191362368	Silent	novel	V254V	0.08
UCEC	chr2	191362309	Missense_Mutation	novel	L235M	0.1
UCEC	chr2	191423902	Missense_Mutation	novel	G1118E	0.49
UCEC	chr2	191276985	Silent	NA	T30T	0.42
UCEC	chr2	191411098	Silent	novel	Q933Q	0.09
UCEC	chr2	191416142	Frame_Shift_Del	novel	*F1063Sfs5**	0.04
UCEC	chr2	191390386	Nonsense_Mutation	NA	R626*	0.24
UCEC	chr2	191400798	Missense_Mutation	NA	A811V	0.14
UCEC	chr2	191381515	Missense_Mutation	NA	Q413H	0.23
UCEC	chr2	191387242	Nonsense_Mutation	novel	G525*	0.09
UCEC	chr2	191402481	Intron	novel		0.38
UCEC	chr2	191387400	Silent	rs368102371	S577S	0.26
UCEC	chr2	191416199	Missense_Mutation	NA	L1082I	0.27
UCEC	chr2	191341494	Missense_Mutation	novel	A127V	0.35
UCEC	chr2	191393119	Missense_Mutation	novel	A708V	0.25
UCEC	chr2	191350163	Missense_Mutation	novel	G167D	0.38
UCEC	chr2	191387377	Missense_Mutation	novel	A570T	0.44
UCEC	chr2	191424154	3'UTR	novel		0.44
UCS	chr2	191362279	Missense_Mutation	novel	L225V	0.45
UCS	chr2	191360676	Missense_Mutation	NA	R203I	0.28

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	AMP	0.1356	0.012962
PAAD	AMP	0.0652	0.1091
PAAD	DEL	0.0326	0.2014

Survival Analysis

Cancer	P-value	Q-value
THYM	0.032	Kaplan-Meier Survival Analysis
KIRC	0.043	Kaplan-Meier Survival Analysis
SARC	0.0016	Kaplan-Meier Survival Analysis
MESO	0.0001	Kaplan-Meier Survival Analysis
HNSC	0.004	Kaplan-Meier Survival Analysis
SKCM	0.043	Kaplan-Meier Survival Analysis
LUSC	0.0035	Kaplan-Meier Survival Analysis
ESCA	0.026	Kaplan-Meier Survival Analysis
KIRP	0.0013	Kaplan-Meier Survival Analysis
CESC	0.012	Kaplan-Meier Survival Analysis
UCEC	0.0095	Kaplan-Meier Survival Analysis
LIHC	0.02	Kaplan-Meier Survival Analysis
LGG	0.0011	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000128641 (Gene tree)
Gene ID: 4430
Gene Symbol: MYO1B
Alias: myr1
Full Name: myosin IB
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 180,205 bases
Position: chr2:191,245,185-191,425,389
Accession: 7596
RBP type: non-canonical RBP
Summary: (Myosin IB) is a Protein Coding gene. Diseases associated with MYO1B include Glass Syndrome and Amebiasis. Among its related pathways are PAK Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include calmodulin binding and motor activity. An important paralog of this gene is MYO1A.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000451437	MYO1B-209	1310	-	ENSP00000388140	303 (aa)	-	E7EQD9
ENST00000496992	MYO1B-214	561	-	-	- (aa)	-	-
ENST00000420448	MYO1B-206	374	-	ENSP00000387610	83 (aa)	-	C9K0I9
ENST00000471904	MYO1B-211	770	-	-	- (aa)	-	-
ENST00000490069	MYO1B-212	2111	-	-	- (aa)	-	-
ENST00000461714	MYO1B-210	562	-	-	- (aa)	-	-
ENST00000392318	MYO1B-204	5082	XM_005246572	ENSP00000376132	1136 (aa)	XP_005246629	O43795
ENST00000438652	MYO1B-208	542	-	ENSP00000399459	149 (aa)	-	C9JUP5
ENST00000494129	MYO1B-213	1880	-	-	- (aa)	-	-
ENST00000427152	MYO1B-207	791	-	ENSP00000408454	192 (aa)	-	H7C2Y7
ENST00000634375	MYO1B-215	567	-	ENSP00000489544	189 (aa)	-	A0A0U1RRI3
ENST00000304164	MYO1B-201	4933	-	ENSP00000306382	1136 (aa)	-	O43795
ENST00000392316	MYO1B-203	4764	XM_024452914	ENSP00000376130	1107 (aa)	XP_024308682	E9PDF6
ENST00000339514	MYO1B-202	5026	XM_024452915	ENSP00000341903	1078 (aa)	XP_024308683	O43795
ENST00000418908	MYO1B-205	572	-	ENSP00000401324	163 (aa)	-	C9JYW1

Gene Model

Click here to download ENSG00000128641's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000128641	Body Weight	2.54864114150903E-6	17903300
ENSG00000128641	Body Weight	1.68783670470051E-8	17903300
ENSG00000128641	Body Mass Index	4.50706366908064E-6	17903300
ENSG00000128641	gamma-Glutamyltransferase	1E-11	22001757
ENSG00000128641	Energy Intake	9E-6	23251661
ENSG00000128641	Antineoplastic Agents	9E-6	23648065
ENSG00000128641	Fluorouracil	9E-6	23648065

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000128641	rs1823913	2	191253321	A	Obesity-related traits	23251661	[NR] g/d increase	0.03	EFO_0003939
ENSG00000128641	rs13030978	2	191252512	T	Liver enzyme levels (gamma-glutamyl transferase)	22001757	[2.80-4.6] % increase	3.7	EFO_0004532
ENSG00000128641	rs1947457	2	191298970	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000128641's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000146	microfilament motor activity	21666684.	IMP	Function
GO:0000146	microfilament motor activity	-	ISS	Function
GO:0005516	calmodulin binding	-	IEA	Function
GO:0005524	ATP binding	21666684.	IMP	Function
GO:0005524	ATP binding	-	ISS	Function
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	-	ISS	Function
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	-	ISS	Function
GO:0005737	cytoplasm	-	ISS	Component
GO:0005769	early endosome	16219689.	IDA	Component
GO:0005884	actin filament	16219689.	IDA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0005886	plasma membrane	-	ISS	Component
GO:0005903	brush border	-	ISS	Component
GO:0006892	post-Golgi vesicle-mediated transport	21666684.	IMP	Process
GO:0007015	actin filament organization	21666684.	IMP	Process
GO:0010008	endosome membrane	16219689.	IDA	Component
GO:0016459	myosin complex	-	IEA	Component
GO:0030048	actin filament-based movement	-	ISS	Process
GO:0030175	filopodium	-	ISS	Component
GO:0030898	actin-dependent ATPase activity	-	IEA	Function
GO:0032588	trans-Golgi network membrane	21666684.	IDA	Component
GO:0045177	apical part of cell	-	IEA	Component
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0048471	perinuclear region of cytoplasm	21666684.	IDA	Component
GO:0051015	actin filament binding	21666684.	IMP	Function
GO:0051017	actin filament bundle assembly	-	ISS	Process
GO:0070062	extracellular exosome	19056867.19199708.	HDA	Component
GO:0071944	cell periphery	-	ISS	Component

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.