EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23027038	The MBD4 Glu346Lys polymorphism is associated with the risk of cervical cancer in a Chinese population.	Int J Gynecol Cancer	2012 Nov	Xiong XD	doi: 10.1097/IGC.0b013e31826e22e4.
19469655	The Glu346Lys polymorphism and frameshift mutations of the Methyl-CpG Binding Domain 4 gene in gastrointestinal cancer.	Neoplasma	2009	Song JH	-
18495292	Tagging single nucleotide polymorphisms in MBD4 are associated with risk of lung cancer in a Chinese population.	Lung Cancer	2008 Dec	Miao R	doi: 10.1016/j.lungcan.2008.03.027
26503472	Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis.	Oncotarget	2015 Dec 15	Tricarico R	doi: 10.18632/oncotarget.5740.
18162445	Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells.	DNA Repair (Amst)	2008 Feb 1	Abdel-Rahman WM	-

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr3	129436912	Silent	novel	K244K	0.24
BLCA	chr3	129437780	Missense_Mutation	novel	R92T	0.27	MBD
BLCA	chr3	129437026	Missense_Mutation	novel	N206K	0.1
BLCA	chr3	129431507	Silent	NA	L579L	0.94
BLCA	chr3	129436531	Silent	novel	L371L	0.37
BLCA	chr3	129431398	3'UTR	novel		0.35
BLCA	chr3	129437276	Missense_Mutation	rs201341528	S123L	0.22	MBD
BLCA	chr3	129437191	Missense_Mutation	novel	I151M	0.28
BRCA	chr3	129439776	Missense_Mutation	NA	V20I	0.22
BRCA	chr3	129439954	5'UTR	novel		0.3
BRCA	chr3	129432531	Missense_Mutation	novel	R546Q	0.09
BRCA	chr3	129436969	Silent	NA	F225F	0.28
BRCA	chr3	129431266	3'UTR	novel		0.42
CESC	chr3	129431439	3'UTR	novel		0.54
CESC	chr3	129436712	Missense_Mutation	NA	K311T	0.53
CESC	chr3	129437847	Missense_Mutation	rs776001887	A70T	0.33
CESC	chr3	129432571	Nonsense_Mutation	NA	E533*	0.38
CESC	chr3	129437847	Missense_Mutation	rs776001887	A70T	0.11
CESC	chr3	129431487	3'UTR	novel		0.31
CESC	chr3	129439863	5'UTR	novel		0.55
CESC	chr3	129433199	Missense_Mutation	novel	S487L	0.3
COAD	chr3	129437905	Missense_Mutation	NA	E50D	0.33
COAD	chr3	129431578	Missense_Mutation	novel	V556M	0.29
COAD	chr3	129437251	Silent	rs753080632	N131N	0.41
COAD	chr3	129437916	Missense_Mutation	rs755035506	G47R	0.09
COAD	chr3	129433140	Missense_Mutation	novel	G507S	0.36
COAD	chr3	129439908	5'UTR	novel		0.21
COAD	chr3	129433125	Missense_Mutation	NA	R512W	0.26
COAD	chr3	129436705	Frame_Shift_Del	novel	*K313Rfs13**	0.05
COAD	chr3	129436899	Missense_Mutation	NA	G249R	0.07
COAD	chr3	129433972	Frame_Shift_Del	novel	*P430Hfs61**	0.1
COAD	chr3	129436705	Frame_Shift_Del	novel	*K313Rfs13**	0.25
COAD	chr3	129432424	Intron	novel		0.12
COAD	chr3	129433102	Missense_Mutation	novel	F519L	0.12
COAD	chr3	129432498	Splice_Region	novel		0.1
COAD	chr3	129437252	Missense_Mutation	rs371283287	N131S	0.63	MBD
COAD	chr3	129436705	Frame_Shift_Del	rs747480541	*E314Kfs4**	0.74
ESCA	chr3	129432419	Intron	novel		0.32
GBM	chr3	129436630	Frame_Shift_Del	novel	*A339Pfs15**	0.22
GBM	chr3	129436998	Frame_Shift_Del	novel	*E216Kfs20**	0.09
GBM	chr3	129432538	Missense_Mutation	novel	S544P	0.07
GBM	chr3	129433944	Frame_Shift_Del	novel	*P440Lfs51**	0.07
GBM	chr3	129437846	Missense_Mutation	novel	A70V	0.47
GBM	chr3	129439777	Silent	novel	T19T	0.14
GBM	chr3	129433115	Missense_Mutation	novel	T515I	0.07
GBM	chr3	129437200	Missense_Mutation	novel	K148N	0.37	MBD
GBM	chr3	129437019	Frame_Shift_Del	novel	*S209Pfs6**	0.09
GBM	chr3	129432427	Intron	novel		0.15
HNSC	chr3	129432464	Intron	novel		0.14
HNSC	chr3	129436983	Missense_Mutation	novel	D221H	0.21
KIRC	chr3	129434074	Missense_Mutation	NA	Y422H	0.21
KIRP	chr3	129437273	Missense_Mutation	novel	L124R	0.74	MBD
KIRP	chr3	129433233	Missense_Mutation	novel	P476T	0.38
LAML	chr3	129431565	Frame_Shift_Ins	novel	*D560Vfs5**	0.13
LAML	chr3	129431568	In_Frame_Del	novel	E559del	0.1
LGG	chr3	129436554	In_Frame_Del	rs758453457	E363del	0.32
LGG	chr3	129439835	5'UTR	rs759821230		0.19
LGG	chr3	129437893	Missense_Mutation	novel	M54I	0.43
LIHC	chr3	129432363	Intron	novel		0.07
LIHC	chr3	129436647	Missense_Mutation	NA	I333L	0.16
LUAD	chr3	129439807	Silent	novel	L9L	0.14
LUAD	chr3	129436892	Missense_Mutation	NA	R251M	0.34
LUAD	chr3	129433143	Missense_Mutation	NA	L506V	0.14
LUSC	chr3	129433880	Missense_Mutation	novel	I461V	0.27
LUSC	chr3	129436543	Silent	novel	R367R	0.18
LUSC	chr3	129439861	5'UTR	novel		0.31
LUSC	chr3	129437018	Missense_Mutation	novel	S209Y	0.24
LUSC	chr3	129436894	Silent	novel	C250C	0.12
LUSC	chr3	129433158	Missense_Mutation	NA	E501Q	0.05
LUSC	chr3	129437155	Silent	novel	L163L	0.12
OV	chr3	129433206	Frame_Shift_Del	novel	*Y485Ifs6**	0.11
OV	chr3	129436738	Silent	NA	V302V	0.25
OV	chr3	129436625	Missense_Mutation	rs372593697	K340R	0.34
READ	chr3	129431455	3'UTR	novel		0.17
READ	chr3	129431549	Missense_Mutation	novel	K565N	0.14
READ	chr3	129436721	Missense_Mutation	novel	S308N	0.32
SKCM	chr3	129437287	Silent	NA	R119R	0.3
SKCM	chr3	129431368	3'UTR	novel		0.39
SKCM	chr3	129433937	Missense_Mutation	rs769817977	R442W	0.48
SKCM	chr3	129433114	Silent	novel	T515T	0.41
SKCM	chr3	129437896	Missense_Mutation	NA	M53I	0.16
SKCM	chr3	129433857	Silent	NA	R468R	0.29
SKCM	chr3	129431397	3'UTR	novel		0.39
SKCM	chr3	129432485	Intron	novel		0.4
STAD	chr3	129434093	Silent	NA	S415S	0.09
STAD	chr3	129436677	Missense_Mutation	NA	F323V	0.39
STAD	chr3	129437294	Missense_Mutation	rs757487617	K117T	0.47	MBD
STAD	chr3	129433943	Missense_Mutation	NA	P440T	0.13
STAD	chr3	129437873	Missense_Mutation	novel	C61Y	0.39
STAD	chr3	129437868	Missense_Mutation	NA	P63S	0.15
STAD	chr3	129436705	Frame_Shift_Del	novel	*K313Rfs13**	0.11
UCEC	chr3	129436847	Missense_Mutation	NA	S266Y	0.29
UCEC	chr3	129433946	Missense_Mutation	novel	T439A	0.27
UCEC	chr3	129436637	Missense_Mutation	novel	F336S	0.11
UCEC	chr3	129436705	Frame_Shift_Del	rs747480541	*E314Kfs4**	0.41
UCEC	chr3	129432374	Intron	novel		0.34
UCEC	chr3	129437828	Missense_Mutation	novel	A76V	0.09
UCEC	chr3	129433917	Silent	novel	V448V	0.41
UCEC	chr3	129431310	3'UTR	novel		0.27
UCEC	chr3	129431461	3'UTR	novel		0.23
UCEC	chr3	129437808	Missense_Mutation	rs370682739	R83C	0.25	MBD
UCEC	chr3	129431449	3'UTR	novel		0.13
UCEC	chr3	129433125	In_Frame_Del	NA	L511del	0.29
UCEC	chr3	129432531	Missense_Mutation	novel	R546Q	0.35
UCEC	chr3	129436914	Missense_Mutation	novel	K244Q	0.4
UCEC	chr3	129431416	3'UTR	novel		0.41
UCEC	chr3	129431338	3'UTR	novel		0.18
UCEC	chr3	129432446	Intron	novel		0.42
UCEC	chr3	129431247	3'UTR	novel		0.3
UCEC	chr3	129431497	3'UTR	novel		0.39
UCEC	chr3	129436851	Nonsense_Mutation	rs374997632	E265*	0.47
UCEC	chr3	129436900	Frame_Shift_Del	NA	*G249Dfs54**	0.46
UCEC	chr3	129439920	5'UTR	novel		0.36
UCEC	chr3	129436512	Missense_Mutation	rs149311534	R378C	0.28
UCEC	chr3	129437276	Nonsense_Mutation	NA	S123*	0.33	MBD
UCEC	chr3	129431409	3'UTR	novel		0.39
UCEC	chr3	129436448	Missense_Mutation	novel	F399C	0.41
UCEC	chr3	129437830	Silent	novel	G75G	0.53
UCEC	chr3	129436585	Frame_Shift_Ins	novel	*L353Ffs4**	0.38
UCEC	chr3	129437051	Missense_Mutation	novel	L198S	0.45
UCEC	chr3	129433888	Missense_Mutation	novel	K458T	0.43
UCEC	chr3	129436885	Missense_Mutation	novel	S253R	0.42
UCEC	chr3	129437301	Nonsense_Mutation	novel	G115*	0.23	MBD
UCEC	chr3	129437013	Missense_Mutation	novel	H211Y	0.36
UCEC	chr3	129436570	Silent	rs139242730	I358I	0.42
UCEC	chr3	129437240	Missense_Mutation	NA	S135Y	0.41	MBD
UCEC	chr3	129439773	Missense_Mutation	NA	T21A	0.39
UCEC	chr3	129437913	Nonsense_Mutation	NA	E48*	0.27
UCEC	chr3	129436761	Missense_Mutation	novel	A295S	0.24
UCEC	chr3	129436867	Silent	novel	Q259Q	0.22
UCEC	chr3	129436976	Missense_Mutation	novel	V223A	0.39
UCEC	chr3	129433871	Missense_Mutation	rs527715494	I464V	0.4
UCEC	chr3	129432428	Intron	novel		0.14
UCEC	chr3	129433116	Frame_Shift_Del	novel	*T515Pfs10**	0.32
UCEC	chr3	129433942	Missense_Mutation	NA	P440H	0.25
UCEC	chr3	129436640	Missense_Mutation	novel	K335R	0.5
UCS	chr3	129436636	Missense_Mutation	novel	F336L	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1778	0.0017784
DLBC	DEL	0.0833	0.18166
GBM	DEL	0.078	0.00094652
KIRC	DEL	0.1723	0.11092
LGG	DEL	0.0585	0.04374
THCA	DEL	0.008	0.221
UCS	DEL	0.1071	0.19877
UVM	DEL	0.5375	0.22482

Survival Analysis

Cancer	P-value	Q-value
THYM	0.035	Kaplan-Meier Survival Analysis
KIRC	0.0073	Kaplan-Meier Survival Analysis
ACC	0.027	Kaplan-Meier Survival Analysis
SKCM	0.00011	Kaplan-Meier Survival Analysis
PRAD	0.011	Kaplan-Meier Survival Analysis
CESC	0.0023	Kaplan-Meier Survival Analysis
KICH	0.011	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
UVM	0.006	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000129071 (Gene tree)
Gene ID: 8930
Gene Symbol: MBD4
Alias: MED1
Full Name: methyl-CpG binding domain 4, DNA glycosylase
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 9,236 bases
Position: chr3:129,430,944-129,440,179
Accession: 6919
RBP type: canonical RBP
Summary: The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000394080	MBD	PF01429.19	2.2e-20	1	1
ENSP00000424873	MBD	PF01429.19	4e-20	1	1
ENSP00000422327	MBD	PF01429.19	4.6e-20	1	1
ENSP00000249910	MBD	PF01429.19	4.7e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23926181	Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct.	Am J Physiol Renal Physiol	2013 Oct 1	Yu Z	doi: 10.1152/ajprenal.00407.2013

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000393278	MBD4-202	1684	-	ENSP00000376959	262 (aa)	-	O95243
ENST00000503197	MBD4-204	2099	-	ENSP00000424873	540 (aa)	-	O95243
ENST00000511009	MBD4-209	530	-	-	- (aa)	-	-
ENST00000515266	MBD4-210	434	-	-	- (aa)	-	-
ENST00000509587	MBD4-207	643	-	-	- (aa)	-	-
ENST00000429544	MBD4-203	2478	-	ENSP00000394080	574 (aa)	-	O95243
ENST00000249910	MBD4-201	2470	-	ENSP00000249910	580 (aa)	-	O95243
ENST00000505883	MBD4-205	613	-	-	- (aa)	-	-
ENST00000509828	MBD4-208	576	-	ENSP00000422690	52 (aa)	-	D6RBI7
ENST00000507208	MBD4-206	2194	XM_024453810	ENSP00000422327	572 (aa)	XP_024309578	O95243

Gene Model

Click here to download ENSG00000129071's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03410	Base excision repair	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000129071	rs2307293	3	129431542	?	Systemic sclerosis (anti-topoisomerase-positive)	29293537			EFO_0008537

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000129071's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000129071	MBD4	65	77.647	ENSAPOG00000021668	mbd4	56	66.507	Acanthochromis_polyacanthus
ENSG00000129071	MBD4	99	77.893	ENSAMEG00000004562	MBD4	99	77.893	Ailuropoda_melanoleuca
ENSG00000129071	MBD4	65	77.647	ENSAOCG00000001157	mbd4	95	42.715	Amphiprion_ocellaris
ENSG00000129071	MBD4	65	77.647	ENSAPEG00000016131	mbd4	95	43.114	Amphiprion_percula
ENSG00000129071	MBD4	93	57.895	ENSAMXG00000017271	mbd4	68	62.443	Astyanax_mexicanus
ENSG00000129071	MBD4	98	93.548	ENSBTAG00000021645	MBD4	100	72.696	Bos_taurus
ENSG00000129071	MBD4	100	97.222	ENSCJAG00000017293	MBD4	100	88.621	Callithrix_jacchus
ENSG00000129071	MBD4	98	79.565	ENSCAFG00000004867	MBD4	99	77.123	Canis_familiaris
ENSG00000129071	MBD4	98	79.565	ENSCAFG00020007082	MBD4	99	77.123	Canis_lupus_dingo
ENSG00000129071	MBD4	98	93.011	ENSCHIG00000009760	MBD4	100	71.130	Capra_hircus
ENSG00000129071	MBD4	100	89.157	ENSCCAG00000029796	MBD4	100	89.157	Cebus_capucinus
ENSG00000129071	MBD4	100	93.565	ENSCATG00000035211	MBD4	100	93.565	Cercocebus_atys
ENSG00000129071	MBD4	97	90.556	ENSCLAG00000008974	MBD4	99	70.578	Chinchilla_lanigera
ENSG00000129071	MBD4	100	93.217	ENSCSAG00000009037	MBD4	100	93.217	Chlorocebus_sabaeus
ENSG00000129071	MBD4	69	86.111	ENSCPBG00000014704	MBD4	89	50.385	Chrysemys_picta_bellii
ENSG00000129071	MBD4	100	93.913	ENSCANG00000007120	MBD4	100	93.913	Colobus_angolensis_palliatus
ENSG00000129071	MBD4	98	94.086	ENSCGRG00001003507	Mbd4	100	67.304	Cricetulus_griseus_chok1gshd
ENSG00000129071	MBD4	98	94.086	ENSCGRG00000010974	Mbd4	100	67.304	Cricetulus_griseus_crigri
ENSG00000129071	MBD4	98	78.448	ENSDNOG00000049619	MBD4	100	76.748	Dasypus_novemcinctus
ENSG00000129071	MBD4	87	64.392	ENSDORG00000000902	-	97	63.808	Dipodomys_ordii
ENSG00000129071	MBD4	88	51.082	ENSEBUG00000010816	mbd4	54	64.118	Eptatretus_burgeri
ENSG00000129071	MBD4	99	79.826	ENSEASG00005014800	MBD4	100	79.826	Equus_asinus_asinus
ENSG00000129071	MBD4	99	80.000	ENSECAG00000022106	MBD4	100	80.000	Equus_caballus
ENSG00000129071	MBD4	89	90.323	ENSEEUG00000011459	MBD4	99	61.525	Erinaceus_europaeus
ENSG00000129071	MBD4	99	79.565	ENSFCAG00000000083	MBD4	99	79.275	Felis_catus
ENSG00000129071	MBD4	68	79.888	ENSFALG00000013663	MBD4	99	45.200	Ficedula_albicollis
ENSG00000129071	MBD4	65	73.529	ENSGMOG00000013830	mbd4	53	68.586	Gadus_morhua
ENSG00000129071	MBD4	67	76.571	ENSGAFG00000016011	mbd4	59	67.453	Gambusia_affinis
ENSG00000129071	MBD4	67	54.595	ENSGACG00000001970	-	80	49.180	Gasterosteus_aculeatus
ENSG00000129071	MBD4	79	77.404	ENSGAGG00000018644	MBD4	89	51.154	Gopherus_agassizii
ENSG00000129071	MBD4	100	98.621	ENSGGOG00000010698	MBD4	100	98.621	Gorilla_gorilla
ENSG00000129071	MBD4	97	92.778	ENSHGLG00000009034	MBD4	99	73.205	Heterocephalus_glaber_female
ENSG00000129071	MBD4	97	92.778	ENSHGLG00100000135	MBD4	99	73.205	Heterocephalus_glaber_male
ENSG00000129071	MBD4	98	96.067	ENSSTOG00000020663	MBD4	100	73.860	Ictidomys_tridecemlineatus
ENSG00000129071	MBD4	65	79.290	ENSKMAG00000015015	mbd4	53	73.545	Kryptolebias_marmoratus
ENSG00000129071	MBD4	65	81.176	ENSLOCG00000013054	MBD4	52	75.936	Lepisosteus_oculatus
ENSG00000129071	MBD4	98	79.565	ENSLAFG00000010609	MBD4	99	75.433	Loxodonta_africana
ENSG00000129071	MBD4	100	93.391	ENSMFAG00000002266	MBD4	100	93.391	Macaca_fascicularis
ENSG00000129071	MBD4	100	92.453	ENSMMUG00000012723	MBD4	100	92.453	Macaca_mulatta
ENSG00000129071	MBD4	99	92.052	ENSMNEG00000029752	MBD4	100	91.993	Macaca_nemestrina
ENSG00000129071	MBD4	100	93.391	ENSMLEG00000024859	MBD4	100	93.391	Mandrillus_leucophaeus
ENSG00000129071	MBD4	100	96.667	ENSMICG00000008022	MBD4	100	82.069	Microcebus_murinus
ENSG00000129071	MBD4	73	48.232	ENSMOCG00000002466	-	97	48.232	Microtus_ochrogaster
ENSG00000129071	MBD4	77	84.804	ENSMODG00000006399	-	99	59.880	Monodelphis_domestica
ENSG00000129071	MBD4	65	80.000	ENSMALG00000021517	mbd4	87	43.496	Monopterus_albus
ENSG00000129071	MBD4	98	95.000	MGP_CAROLIEiJ_G0028760	Mbd4	100	66.609	Mus_caroli
ENSG00000129071	MBD4	98	92.473	ENSMUSG00000030322	Mbd4	100	66.261	Mus_musculus
ENSG00000129071	MBD4	98	93.548	MGP_PahariEiJ_G0022511	-	100	67.361	Mus_pahari
ENSG00000129071	MBD4	98	92.473	MGP_SPRETEiJ_G0029788	Mbd4	100	65.739	Mus_spretus
ENSG00000129071	MBD4	98	96.703	ENSMPUG00000017195	MBD4	99	76.174	Mustela_putorius_furo
ENSG00000129071	MBD4	94	80.000	ENSMLUG00000014766	MBD4	99	80.000	Myotis_lucifugus
ENSG00000129071	MBD4	100	97.241	ENSNLEG00000005337	MBD4	100	97.241	Nomascus_leucogenys
ENSG00000129071	MBD4	50	100.000	ENSMEUG00000015599	-	77	100.000	Notamacropus_eugenii
ENSG00000129071	MBD4	99	93.889	ENSOPRG00000000473	MBD4	99	65.690	Ochotona_princeps
ENSG00000129071	MBD4	65	80.117	ENSONIG00000017212	mbd4	62	70.388	Oreochromis_niloticus
ENSG00000129071	MBD4	79	44.368	ENSOANG00000004589	-	96	44.988	Ornithorhynchus_anatinus
ENSG00000129071	MBD4	99	80.435	ENSOCUG00000013006	MBD4	100	69.125	Oryctolagus_cuniculus
ENSG00000129071	MBD4	88	63.519	ENSORLG00000011049	mbd4	53	78.698	Oryzias_latipes
ENSG00000129071	MBD4	88	63.636	ENSORLG00020020013	mbd4	53	79.290	Oryzias_latipes_hni
ENSG00000129071	MBD4	71	73.016	ENSORLG00015015342	mbd4	55	78.107	Oryzias_latipes_hsok
ENSG00000129071	MBD4	94	60.643	ENSOMEG00000008819	mbd4	52	79.882	Oryzias_melastigma
ENSG00000129071	MBD4	98	82.569	ENSOGAG00000010236	MBD4	100	77.083	Otolemur_garnettii
ENSG00000129071	MBD4	98	93.548	ENSOARG00000014699	MBD4	100	71.478	Ovis_aries
ENSG00000129071	MBD4	100	99.652	ENSPPAG00000036528	MBD4	100	99.652	Pan_paniscus
ENSG00000129071	MBD4	99	97.207	ENSPPRG00000016480	MBD4	99	78.883	Panthera_pardus
ENSG00000129071	MBD4	100	99.483	ENSPTRG00000015377	MBD4	100	99.483	Pan_troglodytes
ENSG00000129071	MBD4	100	93.460	ENSPANG00000015047	MBD4	100	93.460	Papio_anubis
ENSG00000129071	MBD4	79	75.229	ENSPSIG00000007892	MBD4	90	50.375	Pelodiscus_sinensis
ENSG00000129071	MBD4	95	61.942	ENSPEMG00000006226	Mbd4	97	61.524	Peromyscus_maniculatus_bairdii
ENSG00000129071	MBD4	69	92.222	ENSPCIG00000002276	-	100	57.749	Phascolarctos_cinereus
ENSG00000129071	MBD4	75	71.212	ENSPFOG00000014471	mbd4	54	78.363	Poecilia_formosa
ENSG00000129071	MBD4	100	97.391	ENSPPYG00000013417	MBD4	100	97.391	Pongo_abelii
ENSG00000129071	MBD4	89	92.949	ENSPCAG00000012915	MBD4	99	71.429	Procavia_capensis
ENSG00000129071	MBD4	99	79.913	ENSPVAG00000005238	MBD4	99	79.620	Pteropus_vampyrus
ENSG00000129071	MBD4	65	71.345	ENSPNAG00000000509	mbd4	72	56.667	Pygocentrus_nattereri
ENSG00000129071	MBD4	98	81.250	ENSRNOG00000010919	Mbd4	100	66.436	Rattus_norvegicus
ENSG00000129071	MBD4	100	94.261	ENSRBIG00000027722	MBD4	100	94.261	Rhinopithecus_bieti
ENSG00000129071	MBD4	100	94.087	ENSRROG00000029136	MBD4	100	94.087	Rhinopithecus_roxellana
ENSG00000129071	MBD4	99	89.619	ENSSBOG00000016810	MBD4	100	89.100	Saimiri_boliviensis_boliviensis
ENSG00000129071	MBD4	69	91.111	ENSSHAG00000012953	MBD4	94	56.932	Sarcophilus_harrisii
ENSG00000129071	MBD4	67	76.571	ENSSFOG00015016292	mbd4	95	43.145	Scleropages_formosus
ENSG00000129071	MBD4	66	78.736	ENSSMAG00000013958	-	67	44.112	Scophthalmus_maximus
ENSG00000129071	MBD4	85	65.625	ENSSDUG00000001365	mbd4	51	80.000	Seriola_dumerili
ENSG00000129071	MBD4	67	94.318	ENSSARG00000004496	-	80	62.607	Sorex_araneus
ENSG00000129071	MBD4	68	85.475	ENSSPUG00000017344	MBD4	91	49.524	Sphenodon_punctatus
ENSG00000129071	MBD4	98	80.349	ENSSSCG00000033303	MBD4	100	76.389	Sus_scrofa
ENSG00000129071	MBD4	65	75.294	ENSTRUG00000010124	mbd4	53	75.294	Takifugu_rubripes
ENSG00000129071	MBD4	66	67.598	ENSTNIG00000017927	mbd4	55	67.978	Tetraodon_nigroviridis
ENSG00000129071	MBD4	83	85.714	ENSTBEG00000003041	-	77	85.714	Tupaia_belangeri
ENSG00000129071	MBD4	94	79.476	ENSTTRG00000011265	MBD4	98	78.506	Tursiops_truncatus
ENSG00000129071	MBD4	98	73.946	ENSUAMG00000000814	MBD4	99	80.838	Ursus_americanus
ENSG00000129071	MBD4	99	78.957	ENSUMAG00000017542	MBD4	100	78.957	Ursus_maritimus
ENSG00000129071	MBD4	90	59.322	ENSVPAG00000004040	-	70	74.771	Vicugna_pacos
ENSG00000129071	MBD4	98	78.696	ENSVVUG00000014222	MBD4	99	76.644	Vulpes_vulpes
ENSG00000129071	MBD4	71	74.468	ENSXETG00000026622	mbd4	55	71.921	Xenopus_tropicalis
ENSG00000129071	MBD4	65	78.698	ENSXMAG00000021129	mbd4	60	66.981	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000785	chromatin	21873635.	IBA	Component
GO:0003677	DNA binding	21873635.	IBA	Function
GO:0003696	satellite DNA binding	9774669.	TAS	Function
GO:0004520	endodeoxyribonuclease activity	10097147.	TAS	Function
GO:0005515	protein binding	12702765.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006281	DNA repair	10097147.	TAS	Process
GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	14614141.	IDA	Function
GO:0009314	response to radiation	21873635.	IBA	Process
GO:0016607	nuclear speck	-	IDA	Component
GO:0019104	DNA N-glycosylase activity	-	TAS	Function
GO:0032355	response to estradiol	-	IEA	Process
GO:0045008	depyrimidination	-	TAS	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.