EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19787783	PPFIA1 and CCND1 are frequently coamplified in breast cancer.	Genes Chromosomes Cancer	2010 Jan	Dancau AM	doi: 10.1002/gcc.20713.
26663347	Effects of the scaffold proteins liprin-α1, β1 and β2 on invasion by breast cancer cells.	Biol Cell	2016 Mar	Chiaretti S	doi: 10.1111/boc.201500063
27075696	Liprin-α1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery.	Sci Rep	2016 Apr 14	Pehkonen H	doi: 10.1038/srep24486.
28720060	PPFIA1 is upregulated in liver metastasis of breast cancer and is a potential poor prognostic indicator of metastatic relapse.	Tumour Biol	2017 Jul	Yang J	doi: 10.1177/1010428317713492.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr11	70382131	Silent	novel	R1198R	0.09
BLCA	chr11	70332073	Missense_Mutation	novel	Q397H	0.17
BLCA	chr11	70378189	Splice_Site	novel	X1183_splice	0.26
BLCA	chr11	70372377	Missense_Mutation	novel	D1010H	0.35
BLCA	chr11	70283998	Intron	rs368851728		0.17
BLCA	chr11	70348391	Nonsense_Mutation	NA	E712*	0.28
BLCA	chr11	70355762	Silent	NA	K813K	0.31
BLCA	chr11	70326627	Missense_Mutation	NA	E247Q	0.45
BLCA	chr11	70343878	Missense_Mutation	novel	I639M	0.2
BLCA	chr11	70378271	Intron	novel		0.16
BLCA	chr11	70343765	Missense_Mutation	NA	D602H	0.1
BLCA	chr11	70356247	Nonsense_Mutation	NA	Q859*	0.06
BLCA	chr11	70374880	Intron	novel		0.77
BLCA	chr11	70372340	Missense_Mutation	novel	L997F	0.52
BLCA	chr11	70326613	Missense_Mutation	rs747220973	S242F	0.2
BLCA	chr11	70324428	Silent	novel	L97L	0.12
BLCA	chr11	70330287	Missense_Mutation	novel	E349K	0.43
BRCA	chr11	70326287	Missense_Mutation	novel	N211I	0.25
BRCA	chr11	70375018	Silent	novel	A1080A	0.21
BRCA	chr11	70324954	Silent	NA	V158V	0.21
BRCA	chr11	70332028	Silent	novel	L382L	0.1
BRCA	chr11	70372117	Intron	novel		0.34
BRCA	chr11	70356239	Missense_Mutation	NA	R856H	0.11
BRCA	chr11	70343873	Missense_Mutation	rs767442340	A638T	0.5
BRCA	chr11	70272285	Missense_Mutation	novel	Q38P	0.42
BRCA	chr11	70356185	Missense_Mutation	NA	S838L	0.18
BRCA	chr11	70375111	Intron	novel		0.03
BRCA	chr11	70348328	Missense_Mutation	novel	S691G	0.05
BRCA	chr11	70272308	Missense_Mutation	novel	E46K	0.05
BRCA	chr11	70283962	Intron	novel		0.06
BRCA	chr11	70348208	Nonsense_Mutation	NA	E651*	0.11
BRCA	chr11	70354377	Missense_Mutation	novel	R747T	0.05
BRCA	chr11	70372182	Intron	novel		0.04
BRCA	chr11	70374880	Intron	novel		0.04
BRCA	chr11	70375130	Intron	novel		0.08
BRCA	chr11	70324963	Silent	NA	L161L	0.27
BRCA	chr11	70378309	Intron	novel		0.17
BRCA	chr11	70378166	Missense_Mutation	NA	S1174F	0.13
CESC	chr11	70325497	Splice_Region	novel		0.17
CESC	chr11	70348353	Missense_Mutation	rs149738073	R699H	0.41
CESC	chr11	70383153	3'UTR	novel		0.5
CESC	chr11	70332085	Silent	rs775657756	A401A	0.41
CESC	chr11	70348400	Frame_Shift_Ins	novel	*R715Ifs25**	0.05
CESC	chr11	70337426	Missense_Mutation	novel	K497R	0.24
CESC	chr11	70383319	3'UTR	novel		0.09
CESC	chr11	70324912	Silent	NA	V144V	0.28
CESC	chr11	70376583	Missense_Mutation	NA	D1123N	0.35
CESC	chr11	70326662	Missense_Mutation	novel	I258M	0.23
COAD	chr11	70326267	Missense_Mutation	NA	M204I	0.43
COAD	chr11	70343836	Silent	rs745358718	A625A	0.39
COAD	chr11	70284024	Intron	novel		0.16
COAD	chr11	70272425	Missense_Mutation	NA	A85T	0.38
COAD	chr11	70330315	Missense_Mutation	rs745504916	R358Q	0.22
COAD	chr11	70326753	Missense_Mutation	novel	T289S	0.19
COAD	chr11	70272318	Missense_Mutation	rs750251702	R49H	0.11
COAD	chr11	70356235	Missense_Mutation	novel	N855H	0.22
COAD	chr11	70348223	Missense_Mutation	rs141485507	R656W	0.31
COAD	chr11	70374890	Intron	novel		0.31
COAD	chr11	70355727	Missense_Mutation	novel	G802C	0.08
COAD	chr11	70343699	Missense_Mutation	rs748672100	R580C	0.41
COAD	chr11	70378032	Splice_Region	NA	D1129D	0.36
COAD	chr11	70355664	Frame_Shift_Del	NA	V781*	0.37
COAD	chr11	70375096	Splice_Region	novel		0.11
COAD	chr11	70331969	Frame_Shift_Del	novel	*N364Tfs19**	0.44
COAD	chr11	70272214	Frame_Shift_Del	novel	*P16Lfs24**	0.32
COAD	chr11	70374681	Intron	novel		0.57
COAD	chr11	70375024	Silent	rs373783497	L1082L	0.41
DLBC	chr11	70324949	Missense_Mutation	novel	E157K	0.22
ESCA	chr11	70383108	3'UTR	novel		0.19
ESCA	chr11	70343828	Missense_Mutation	novel	A623T	0.09
ESCA	chr11	70372214	Splice_Site	novel	X956_splice	0.14
ESCA	chr11	70326607	Missense_Mutation	novel	D240A	0.05
GBM	chr11	70324996	Frame_Shift_Ins	novel	*A173Cfs4**	0.23
GBM	chr11	70330315	Missense_Mutation	rs745504916	R358Q	0.23
GBM	chr11	70374780	Intron	novel		0.27
GBM	chr11	70335649	Silent	rs374923538	R461R	0.43
GBM	chr11	70324505	Splice_Site	novel	X122_splice	0.07
GBM	chr11	70337407	Missense_Mutation	novel	E491K	0.37
HNSC	chr11	70325000	Missense_Mutation	novel	L174V	0.04
HNSC	chr11	70330268	Silent	novel	L342L	0.04
HNSC	chr11	70378197	Splice_Site	novel	X1184_splice	0.22
HNSC	chr11	70330242	Missense_Mutation	rs568113048	R334C	0.35
HNSC	chr11	70362345	Missense_Mutation	novel	G908R	0.13
HNSC	chr11	70378263	Intron	novel		0.09
HNSC	chr11	70326703	Missense_Mutation	novel	R272P	0.06
HNSC	chr11	70378161	Silent	rs374468603	S1172S	0.09
HNSC	chr11	70372507	Silent	novel	L1024L	0.14
HNSC	chr11	70284021	Intron	novel		0.3
HNSC	chr11	70324428	Silent	novel	L97L	0.05
KIRC	chr11	70348225	Silent	novel	R656R	0.15
KIRC	chr11	70372498	Silent	NA	I1021I	0.09
KIRC	chr11	70338453	Missense_Mutation	NA	G524D	0.3
KIRC	chr11	70355782	Missense_Mutation	NA	G820E	0.3
KIRC	chr11	70326774	In_Frame_Del	novel	K296_E298del	0.22
KIRP	chr11	70333516	Missense_Mutation	novel	E420A	0.42
KIRP	chr11	70356179	Missense_Mutation	rs778796834	D836V	0.39
LGG	chr11	70362158	Silent	NA	T882T	0.41
LGG	chr11	70324923	Missense_Mutation	rs749928660	A148V	0.34
LGG	chr11	70326279	Silent	novel	E208E	0.32
LIHC	chr11	70348259	Missense_Mutation	novel	S668R	0.43
LIHC	chr11	70355742	Missense_Mutation	novel	I807F	0.14
LUAD	chr11	70324895	Missense_Mutation	NA	L139V	0.29
LUAD	chr11	70374804	Intron	novel		0.31
LUAD	chr11	70272193	Silent	NA	P7P	0.18
LUAD	chr11	70330208	Silent	novel	I322I	0.2
LUAD	chr11	70355717	Silent	novel	P798P	0.44
LUAD	chr11	70348287	Nonsense_Mutation	NA	S677*	0.12
LUAD	chr11	70372479	Frame_Shift_Del	novel	*N1015Kfs15**	0.07
LUAD	chr11	70326748	Missense_Mutation	NA	L287Q	0.13
LUAD	chr11	70326657	Missense_Mutation	NA	E257K	0.28
LUAD	chr11	70374965	Missense_Mutation	NA	I1063L	0.13
LUSC	chr11	70343883	Missense_Mutation	NA	K641I	0.19
LUSC	chr11	70335609	Nonsense_Mutation	novel	S448*	0.05
LUSC	chr11	70354311	Missense_Mutation	novel	S725F	0.04
LUSC	chr11	70283962	Intron	novel		0.29
LUSC	chr11	70339280	Missense_Mutation	novel	A561T	0.69
LUSC	chr11	70324428	Silent	novel	L97L	0.23
LUSC	chr11	70343715	Missense_Mutation	rs151134329	S585I	0.04
LUSC	chr11	70356219	Silent	novel	G849G	0.06
LUSC	chr11	70324963	Silent	rs773179632	L161L	0.05
LUSC	chr11	70378196	Splice_Site	novel	X1184_splice	0.11
LUSC	chr11	70272425	Missense_Mutation	NA	A85T	0.06
LUSC	chr11	70354313	Missense_Mutation	novel	R726G	0.06
LUSC	chr11	70362415	Missense_Mutation	novel	R931M	0.05
LUSC	chr11	70354352	Missense_Mutation	NA	E739K	0.33
LUSC	chr11	70330204	Missense_Mutation	NA	R321I	0.25
LUSC	chr11	70326810	Missense_Mutation	NA	V308I	0.36
LUSC	chr11	70375114	Intron	novel		0.13
LUSC	chr11	70339260	Missense_Mutation	rs370268058	R554H	0.07
LUSC	chr11	70332080	Missense_Mutation	NA	A400P	0.42
LUSC	chr11	70325527	Missense_Mutation	NA	E187Q	0.45
LUSC	chr11	70326788	Missense_Mutation	NA	M300I	0.4
LUSC	chr11	70324923	Missense_Mutation	rs749928660	A148V	0.34
LUSC	chr11	70356226	Missense_Mutation	novel	A852T	0.34
OV	chr11	70374929	Missense_Mutation	novel	W1051G	0.07
OV	chr11	70375053	Frame_Shift_Ins	novel	*L1093Tfs23**	0.06
OV	chr11	70348391	Missense_Mutation	novel	E712K	0.07
OV	chr11	70348257	Missense_Mutation	NA	G667A	0.41
OV	chr11	70325551	Missense_Mutation	novel	E195K	0.08
OV	chr11	70324918	Silent	novel	R146R	0.04
OV	chr11	70375126	Intron	novel		0.35
OV	chr11	70335647	Frame_Shift_Ins	novel	*R461Kfs27**	0.07
OV	chr11	70335674	Nonsense_Mutation	novel	*M470delinsRFTMNL**	0.2
PAAD	chr11	70324446	Silent	novel	Q103Q	0.04
PAAD	chr11	70362117	Missense_Mutation	rs201951162	R869W	0.15
PAAD	chr11	70378155	Missense_Mutation	novel	M1170I	0.17
PRAD	chr11	70375050	Missense_Mutation	NA	S1091I	0.13
READ	chr11	70331974	Missense_Mutation	novel	N364K	0.2
READ	chr11	70272245	Missense_Mutation	novel	G25S	0.32
READ	chr11	70356198	Silent	NA	A842A	0.25
READ	chr11	70378109	Missense_Mutation	novel	G1155A	0.09
READ	chr11	70326601	Missense_Mutation	novel	S238Y	0.36
READ	chr11	70378179	Missense_Mutation	novel	K1178N	0.4
READ	chr11	70372527	Missense_Mutation	rs754825169	R1031Q	0.08
READ	chr11	70272203	Missense_Mutation	rs751196245	E11K	0.17
READ	chr11	70326744	Missense_Mutation	novel	D286Y	0.52
SARC	chr11	70343690	Missense_Mutation	novel	D577Y	0.34
SARC	chr11	70338397	Missense_Mutation	novel	E505D	0.49
SARC	chr11	70378138	Missense_Mutation	rs373954004	R1165W	0.85
SKCM	chr11	70378174	Missense_Mutation	novel	P1177S	0.43
SKCM	chr11	70378175	Missense_Mutation	novel	P1177L	0.42
SKCM	chr11	70348357	Silent	NA	S700S	0.14
SKCM	chr11	70362295	Missense_Mutation	NA	V891A	0.23
SKCM	chr11	70372106	Intron	novel		0.3
SKCM	chr11	70272298	Silent	NA	S42S	0.16
SKCM	chr11	70343817	Missense_Mutation	NA	P619L	0.13
SKCM	chr11	70324909	Silent	NA	V143V	0.44
SKCM	chr11	70339273	Silent	novel	G558G	0.45
SKCM	chr11	70339274	Missense_Mutation	novel	R559W	0.46
SKCM	chr11	70343819	Missense_Mutation	NA	S620G	0.18
SKCM	chr11	70362295	Missense_Mutation	NA	V891A	0.36
SKCM	chr11	70348336	Silent	novel	S693S	0.46
SKCM	chr11	70337371	Missense_Mutation	NA	L479F	0.6
SKCM	chr11	70362363	Silent	NA	L914L	0.34
SKCM	chr11	70348356	Missense_Mutation	NA	S700F	0.6
SKCM	chr11	70348320	Missense_Mutation	rs748263753	S688L	0.46
SKCM	chr11	70332090	Missense_Mutation	NA	S403F	0.46
SKCM	chr11	70376576	Missense_Mutation	novel	M1120I	0.38
SKCM	chr11	70376577	Missense_Mutation	novel	G1121R	0.38
SKCM	chr11	70382100	Missense_Mutation	NA	G1188E	0.15
SKCM	chr11	70362108	Missense_Mutation	NA	E866K	0.28
SKCM	chr11	70332049	Silent	rs771835705	P389P	0.21
SKCM	chr11	70332050	Missense_Mutation	novel	E390K	0.21
SKCM	chr11	70343814	Missense_Mutation	NA	S618L	0.15
SKCM	chr11	70362116	Silent	NA	A868A	0.19
SKCM	chr11	70339273	Silent	NA	G558G	0.27
SKCM	chr11	70338418	Silent	NA	D512D	0.3
SKCM	chr11	70348361	Missense_Mutation	rs779080896	P702S	0.26
SKCM	chr11	70343791	Silent	novel	L610L	0.63
SKCM	chr11	70355774	Silent	rs145603046	G817G	0.52
STAD	chr11	70354374	Missense_Mutation	NA	P746L	0.26
STAD	chr11	70343836	Silent	rs745358718	A625A	0.1
STAD	chr11	70283968	Intron	novel		0.14
STAD	chr11	70375043	Missense_Mutation	rs747502376	D1089N	0.22
STAD	chr11	70337394	Frame_Shift_Del	novel	*K488Sfs3**	0.27
STAD	chr11	70356223	Missense_Mutation	novel	Q851E	0.04
STAD	chr11	70375040	Missense_Mutation	novel	F1088V	0.18
STAD	chr11	70372375	Missense_Mutation	NA	V1009G	0.23
STAD	chr11	70343836	Silent	rs745358718	A625A	0.33
STAD	chr11	70378140	Silent	novel	R1165R	0.43
STAD	chr11	70374831	Intron	novel		0.14
STAD	chr11	70272318	Missense_Mutation	rs750251702	R49H	0.33
STAD	chr11	70354389	Missense_Mutation	novel	L751S	0.51
STAD	chr11	70356248	Frame_Shift_Del	NA	*K861Sfs27**	0.51
TGCT	chr11	70378145	Missense_Mutation	novel	T1167S	0.42
UCEC	chr11	70362481	Missense_Mutation	novel	S953C	0.9
UCEC	chr11	70356248	Frame_Shift_Del	NA	*K861Sfs27**	0.45
UCEC	chr11	70331966	Missense_Mutation	NA	D362Y	0.28
UCEC	chr11	70335672	Missense_Mutation	NA	R469I	0.29
UCEC	chr11	70343836	Silent	rs745358718	A625A	0.11
UCEC	chr11	70375042	Silent	novel	F1088F	0.33
UCEC	chr11	70284047	Intron	novel		0.26
UCEC	chr11	70362158	Silent	NA	T882T	0.23
UCEC	chr11	70378088	Missense_Mutation	novel	D1148G	0.5
UCEC	chr11	70348295	Missense_Mutation	NA	S680P	0.39
UCEC	chr11	70272206	Missense_Mutation	novel	A12S	0.35
UCEC	chr11	70335603	Missense_Mutation	NA	R446H	0.4
UCEC	chr11	70325509	Nonsense_Mutation	novel	R181*	0.29
UCEC	chr11	70378119	Silent	novel	E1158E	0.44
UCEC	chr11	70354379	Missense_Mutation	novel	A748S	0.45
UCEC	chr11	70376557	Missense_Mutation	NA	F1114C	0.17
UCEC	chr11	70374984	Missense_Mutation	novel	A1069V	0.08
UCEC	chr11	70382153	3'UTR	novel		0.12
UCEC	chr11	70272271	Silent	novel	D33D	0.63
UCEC	chr11	70325515	Nonsense_Mutation	novel	R183*	0.63
UCEC	chr11	70326353	Missense_Mutation	rs778116748	T233M	0.53
UCEC	chr11	70343784	Missense_Mutation	NA	D608G	0.23
UCEC	chr11	70374920	Missense_Mutation	rs746898657	V1048M	0.09
UCEC	chr11	70348358	Missense_Mutation	NA	T701A	0.37
UCEC	chr11	70325516	Missense_Mutation	rs758180487	R183Q	0.19
UCEC	chr11	70272234	Missense_Mutation	rs145854073	G21D	0.27
UCEC	chr11	70283998	Intron	rs368851728		0.46
UCEC	chr11	70324938	Missense_Mutation	NA	G153D	0.56
UCEC	chr11	70356248	Frame_Shift_Del	NA	*K861Sfs27**	0.24
UCEC	chr11	70372377	Missense_Mutation	rs752611402	D1010N	0.47
UCEC	chr11	70383398	3'UTR	novel		0.28
UCEC	chr11	70383360	3'UTR	novel		0.31
UCEC	chr11	70378195	Missense_Mutation	novel	G1184S	0.24
UCEC	chr11	70272202	Silent	rs763700052	S10S	0.32
UCEC	chr11	70272425	Missense_Mutation	NA	A85T	0.27
UCEC	chr11	70330281	Missense_Mutation	rs759948657	E347Q	0.1
UCEC	chr11	70324949	Missense_Mutation	novel	E157K	0.29
UCEC	chr11	70325531	Missense_Mutation	novel	R188I	0.1
UCEC	chr11	70326692	Missense_Mutation	novel	Q268H	0.39
UCEC	chr11	70326648	Nonsense_Mutation	NA	E254*	0.23
UCEC	chr11	70330179	Missense_Mutation	novel	A313T	0.36
UCEC	chr11	70383414	3'UTR	novel		0.44
UCEC	chr11	70335587	Missense_Mutation	novel	E441K	0.38
UCEC	chr11	70378030	Missense_Mutation	novel	D1129Y	0.26
UCEC	chr11	70362384	Missense_Mutation	NA	R921C	0.38
UCEC	chr11	70376565	Missense_Mutation	NA	L1117I	0.06
UCEC	chr11	70372357	Missense_Mutation	novel	R1003Q	0.32
UCEC	chr11	70375036	Missense_Mutation	novel	E1086D	0.33
UCEC	chr11	70375165	Intron	novel		0.6
UCEC	chr11	70383184	3'UTR	novel		0.37
UCEC	chr11	70383470	3'UTR	novel		0.5
UCEC	chr11	70355806	Missense_Mutation	novel	G828E	0.31
UCEC	chr11	70375018	Silent	novel	A1080A	0.37
UCEC	chr11	70326607	Missense_Mutation	novel	D240A	0.12
UCEC	chr11	70354385	Missense_Mutation	rs374396970	R750W	0.16
UCEC	chr11	70362328	Missense_Mutation	novel	R902Q	0.2
UCEC	chr11	70372220	Silent	rs775502696	L957L	0.26
UCEC	chr11	70372357	Missense_Mutation	novel	R1003Q	0.15
UCEC	chr11	70372527	Missense_Mutation	rs754825169	R1031Q	0.15
UCEC	chr11	70339173	Missense_Mutation	rs149790526	R525Q	0.31
UCEC	chr11	70362487	Missense_Mutation	rs143895504	T955M	0.4
UCEC	chr11	70384346	3'UTR	novel		0.3
UCEC	chr11	70348244	Nonsense_Mutation	novel	R663*	0.31
UCEC	chr11	70372140	Intron	novel		0.4
UCEC	chr11	70378278	Intron	novel		0.38
UCEC	chr11	70348365	Missense_Mutation	rs748144424	R703Q	0.44
UCEC	chr11	70351015	Intron	novel		0.37
UCEC	chr11	70343743	Silent	rs150317909	F594F	0.5
UCEC	chr11	70324423	Nonsense_Mutation	novel	E96*	0.05
UCEC	chr11	70284020	Intron	novel		0.16
UCEC	chr11	70362318	Missense_Mutation	novel	A899T	0.11
UCEC	chr11	70324433	Missense_Mutation	novel	V99A	0.22
UCEC	chr11	70325000	Missense_Mutation	novel	L174M	0.23
UCEC	chr11	70378138	Missense_Mutation	rs373954004	R1165W	0.36
UCEC	chr11	70339190	Missense_Mutation	novel	V531I	0.4
UCEC	chr11	70337380	Nonsense_Mutation	NA	E482*	0.14
UCEC	chr11	70376557	Missense_Mutation	NA	F1114C	0.45
UCEC	chr11	70365435	Intron	novel		0.37
UCEC	chr11	70272403	Silent	novel	S77S	0.17
UCEC	chr11	70324960	Silent	novel	V160V	0.19
UCEC	chr11	70331992	Silent	novel	R370R	0.22
UCEC	chr11	70356247	Nonsense_Mutation	NA	Q859*	0.35
UCEC	chr11	70362118	Missense_Mutation	rs761275496	R869Q	0.35
UCEC	chr11	70356247	Frame_Shift_Ins	novel	*H862Afs2**	0.15
UCEC	chr11	70343668	Splice_Site	novel	X570_splice	0.09
UCEC	chr11	70272214	Silent	NA	G14G	0.21
UCEC	chr11	70355813	Splice_Site	novel	X830_splice	0.5
UCEC	chr11	70374869	Intron	novel		0.38
UCEC	chr11	70343678	Missense_Mutation	novel	L573I	0.26
UCEC	chr11	70362311	Nonsense_Mutation	novel	W896*	0.28
UCS	chr11	70324407	Silent	rs770312900	F90F	0.4
UCS	chr11	70325510	Missense_Mutation	rs372608196	R181Q	0.31
UVM	chr11	70362369	Missense_Mutation	rs750191381	D916N	0.09

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	AMP	0.122	1.2477e-08
ESCA	AMP	0.5109	0.018342
HNSC	AMP	0.4004	7.9657e-252
LUSC	AMP	0.2974	5.606e-77
TGCT	DEL	0.72	0.21504

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0011	Kaplan-Meier Survival Analysis
HNSC	0.0098	Kaplan-Meier Survival Analysis
PAAD	0.009	Kaplan-Meier Survival Analysis
CESC	0.022	Kaplan-Meier Survival Analysis
READ	0.015	Kaplan-Meier Survival Analysis
KICH	0.0042	Kaplan-Meier Survival Analysis
LIHC	0.009	Kaplan-Meier Survival Analysis
LGG	0.00014	Kaplan-Meier Survival Analysis
OV	0.0047	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000131626 (Gene tree)
Gene ID: 8500
Gene Symbol: PPFIA1
Alias: LIP.1|LIPRIN
Full Name: PTPRF interacting protein alpha 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 114,626 bases
Position: chr11:70,270,687-70,385,312
Accession: 9245
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22820175	The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline.	Biochim Biophys Acta	2012 Oct	Cha DS	doi: 10.1016/j.bbamcr.2012.07.006

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000532793	PPFIA1-223	550	-	-	- (aa)	-	-
ENST00000528853	PPFIA1-212	745	-	ENSP00000434692	98 (aa)	-	H0YDZ8
ENST00000530746	PPFIA1-216	575	-	ENSP00000432722	158 (aa)	-	E9PPF6
ENST00000532024	PPFIA1-220	563	-	ENSP00000432065	99 (aa)	-	E9PID5
ENST00000389547	PPFIA1-202	4133	XM_017018450	ENSP00000374198	1185 (aa)	XP_016873939	Q13136
ENST00000528750	PPFIA1-211	1168	-	ENSP00000434445	389 (aa)	-	H0YDW2
ENST00000648755	PPFIA1-227	6705	-	ENSP00000497908	166 (aa)	-	-
ENST00000530390	PPFIA1-214	879	-	ENSP00000435978	46 (aa)	-	H0YEK0
ENST00000638133	PPFIA1-225	814	-	ENSP00000490647	271 (aa)	-	A0A1B0GVT3
ENST00000530798	PPFIA1-217	710	-	ENSP00000433114	237 (aa)	-	H0YD72
ENST00000526369	PPFIA1-208	564	-	ENSP00000437024	97 (aa)	-	H0YF15
ENST00000530932	PPFIA1-218	536	-	-	- (aa)	-	-
ENST00000530548	PPFIA1-215	3774	-	-	- (aa)	-	-
ENST00000528284	PPFIA1-210	568	-	-	- (aa)	-	-
ENST00000644155	PPFIA1-226	5996	XM_006718716	ENSP00000496327	1224 (aa)	XP_006718779	A0A2R8Y7R9
ENST00000526262	PPFIA1-206	4537	-	ENSP00000435752	387 (aa)	-	H0YEF9
ENST00000532504	PPFIA1-222	5159	-	ENSP00000433619	583 (aa)	-	E9PJZ7
ENST00000253925	PPFIA1-201	5234	XM_011545311	ENSP00000253925	1202 (aa)	XP_011543613	Q13136
ENST00000533894	PPFIA1-224	553	-	ENSP00000432913	33 (aa)	-	H0YD39
ENST00000531657	PPFIA1-219	3036	-	-	- (aa)	-	-
ENST00000526347	PPFIA1-207	862	-	-	- (aa)	-	-
ENST00000532443	PPFIA1-221	587	-	-	- (aa)	-	-
ENST00000527612	PPFIA1-209	598	-	-	- (aa)	-	-
ENST00000525922	PPFIA1-204	358	-	-	- (aa)	-	-
ENST00000526074	PPFIA1-205	573	-	-	- (aa)	-	-
ENST00000525530	PPFIA1-203	514	-	-	- (aa)	-	-
ENST00000530294	PPFIA1-213	977	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000131626's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000131626's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	11931740.12923177.16189514.19060904.25416956.26496610.	IPI	Function
GO:0005737	cytoplasm	7796809.	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005925	focal adhesion	-	IDA	Component
GO:0007160	cell-matrix adhesion	7796809.	TAS	Process
GO:0007165	signal transduction	7796809.	TAS	Process
GO:0007269	neurotransmitter secretion	-	TAS	Process
GO:0014047	glutamate secretion	-	TAS	Process
GO:0048786	presynaptic active zone	15217342.	TAS	Component
GO:0051497	negative regulation of stress fiber assembly	22266902.	IMP	Process
GO:1903077	negative regulation of protein localization to plasma membrane	22266902.	IMP	Process

EuRBPDB

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.