EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26360781	Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival.	Oncotarget	2015 Oct 13	He LR	doi: 10.18632/oncotarget.5070.
25153161	Presence of CHD1L over-expression is associated with aggressive tumor biology and is a novel prognostic biomarker for patient survival in human breast cancer.	PLoS One	2014 Aug 25	Wu J	doi: 10.1371/journal.pone.0098673
23807680	Expression of CHD1L in bladder cancer and its influence on prognosis and survival.	Tumour Biol	2013 Dec	Tian F	doi: 10.1007/s13277-013-0951-4
24258459	CHD1L is a novel independent prognostic factor for gastric cancer.	Clin Transl Oncol	2014 Aug	Su Z	doi: 10.1007/s12094-013-1136-8
26599012	Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.	PLoS One	2015 Nov 23	Mu QJ	doi: 10.1371/journal.pone.0143030
30024537	Prognostic role of chromodomain helicase DNA binding protein 1-like protein in human solid cancers: A meta-analysis.	Medicine (Baltimore)	2018 Jul	Liu W	doi: 10.1097/MD.0000000000011522.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	147286383	Missense_Mutation	novel	E702K	0.12
BLCA	chr1	147276220	Missense_Mutation	novel	L501P	0.08
BLCA	chr1	147291486	Silent	novel	L775L	0.13
BLCA	chr1	147275449	Missense_Mutation	NA	H456N	0.48
BLCA	chr1	147254966	Missense_Mutation	novel	E113Q	0.3	ResIII
BLCA	chr1	147286430	Silent	novel	L717L	0.2
BRCA	chr1	147294458	Missense_Mutation	NA	W852C	0.2
BRCA	chr1	147286497	Missense_Mutation	rs142193146	V740L	0.46
BRCA	chr1	147285366	Missense_Mutation	rs200997862	R633W	0.24
BRCA	chr1	147252673	Missense_Mutation	rs782045573	R60C	0.23	ResIII
BRCA	chr1	147287685	Nonsense_Mutation	rs190301424	R758*	0.18
BRCA	chr1	147276110	Frame_Shift_Ins	NA	*V466Sfs16**	0.12
BRCA	chr1	147291515	Missense_Mutation	novel	V785D	0.03
BRCA	chr1	147285450	Missense_Mutation	novel	K661E	0.08
BRCA	chr1	147264539	Missense_Mutation	NA	D232H	0.23
BRCA	chr1	147287686	Missense_Mutation	NA	R758P	0.3
BRCA	chr1	147284350	Splice_Site	NA	X569_splice	0.18
BRCA	chr1	147286371	Missense_Mutation	NA	E698Q	0.2
BRCA	chr1	147242706	Translation_Start_Site	novel	M1?	1
BRCA	chr1	147259956	Intron	novel		0.11
CESC	chr1	147284486	Missense_Mutation	rs782711426	R614Q	0.43
CESC	chr1	147280071	Missense_Mutation	novel	E529K	0.26
CESC	chr1	147265931	Splice_Site	novel	X247_splice	0.22
CESC	chr1	147270936	Missense_Mutation	novel	H364Y	0.38
CHOL	chr1	147259627	Intron	novel		0.41
COAD	chr1	147286402	Missense_Mutation	NA	D708A	0.32
COAD	chr1	147254871	Missense_Mutation	NA	T81I	0.54	ResIII
COAD	chr1	147255880	Missense_Mutation	novel	D139H	0.09	ResIII
COAD	chr1	147242817	Silent	novel	Q38Q	0.36
COAD	chr1	147259627	Intron	novel		0.55
COAD	chr1	147252621	Splice_Site	NA	X43_splice	0.11
COAD	chr1	147259627	Intron	novel		0.59
COAD	chr1	147264424	Splice_Region	NA	F193F	0.38
COAD	chr1	147287691	Missense_Mutation	rs782687350	A760T	0.11
COAD	chr1	147254974	Nonsense_Mutation	novel	*R116Ffs2**	0.05	ResIII
COAD	chr1	147267468	Missense_Mutation	NA	N313S	0.12
COAD	chr1	147280193	Splice_Site	rs587622399	X569_splice	0.55
ESCA	chr1	147264552	Missense_Mutation	rs201333837	R236H	0.06
ESCA	chr1	147255863	Missense_Mutation	novel	R133T	0.22	ResIII
ESCA	chr1	147286437	Missense_Mutation	rs200761960	V720I	0.12
GBM	chr1	147287711	Nonsense_Mutation	novel	Y766*	0.03
GBM	chr1	147264452	Missense_Mutation	rs148845749	G203R	0.44
GBM	chr1	147272278	Missense_Mutation	novel	A423T	0.38
GBM	chr1	147286364	Missense_Mutation	novel	E695D	0.17
GBM	chr1	147259825	Intron	novel		0.07
GBM	chr1	147259805	Intron	novel		0.43
GBM	chr1	147265993	Silent	novel	A267A	0.07
GBM	chr1	147286495	Missense_Mutation	novel	C739F	0.2
GBM	chr1	147294472	Missense_Mutation	NA	R857Q	0.05
GBM	chr1	147266002	Silent	novel	L270L	0.05
HNSC	chr1	147284477	Missense_Mutation	rs368838337	R611Q	0.2
HNSC	chr1	147293636	Missense_Mutation	novel	D807A	0.18
HNSC	chr1	147267432	Missense_Mutation	NA	F301C	0.23
HNSC	chr1	147276201	Missense_Mutation	novel	E495Q	0.05
HNSC	chr1	147280189	Missense_Mutation	rs781830629	G568V	0.16
HNSC	chr1	147291481	Splice_Site	novel	X774_splice	0.13
KIRP	chr1	147275460	Silent	NA	G459G	0.33
LAML	chr1	147294492	Missense_Mutation	novel	A864T	0.04
LGG	chr1	147264572	Nonsense_Mutation	NA	E243*	0.3
LGG	chr1	147267488	Missense_Mutation	novel	K320Q	0.11
LIHC	chr1	147276257	Splice_Region	NA	Q513Q	0.34
LIHC	chr1	147285330	Frame_Shift_Ins	novel	*G623Rfs47**	0.12
LIHC	chr1	147259696	Intron	novel		0.65
LIHC	chr1	147276229	Missense_Mutation	NA	Q504L	0.79
LIHC	chr1	147293721	Missense_Mutation	novel	K835N	0.06
LUAD	chr1	147286400	Silent	novel	L707L	0.39
LUAD	chr1	147286401	Missense_Mutation	novel	D708Y	0.38
LUAD	chr1	147287733	Frame_Shift_Ins	novel	*S776Pfs12**	0.15
LUAD	chr1	147266084	Missense_Mutation	novel	L298V	0.13
LUAD	chr1	147286414	Missense_Mutation	novel	P712L	0.39
LUAD	chr1	147287723	Silent	NA	G770G	0.13
LUAD	chr1	147284408	Frame_Shift_Del	novel	*R589Wfs2**	0.24
LUAD	chr1	147284422	Missense_Mutation	NA	E593Q	0.09
LUAD	chr1	147276179	Silent	NA	L487L	0.1
LUAD	chr1	147275468	Missense_Mutation	novel	K462M	0.28
LUSC	chr1	147286295	Splice_Region	novel		0.17
LUSC	chr1	147259857	Missense_Mutation	novel	V172A	0.23
LUSC	chr1	147242702	5'UTR	rs782474002		0.71
LUSC	chr1	147295603	3'UTR	novel		0.17
LUSC	chr1	147280125	Missense_Mutation	novel	D547Y	0.24
LUSC	chr1	147255901	Missense_Mutation	novel	F146I	0.28	ResIII
LUSC	chr1	147267464	Nonsense_Mutation	NA	Q312*	0.19
LUSC	chr1	147285428	Silent	NA	K653K	0.21
LUSC	chr1	147284396	Missense_Mutation	novel	P584L	0.15
LUSC	chr1	147293649	Silent	NA	V811V	0.05
LUSC	chr1	147294423	Missense_Mutation	NA	P841S	0.15
LUSC	chr1	147276184	Missense_Mutation	novel	L489P	0.22
LUSC	chr1	147285329	Silent	novel	L620L	0.14
LUSC	chr1	147275423	Missense_Mutation	novel	N447T	0.04
OV	chr1	147285331	Missense_Mutation	novel	I621T	0.14
OV	chr1	147295430	Splice_Site	rs782291956	X872_splice	0.26
OV	chr1	147280170	Missense_Mutation	NA	S562C	0.12
OV	chr1	147259809	Intron	novel		0.07
PAAD	chr1	147259854	Missense_Mutation	novel	L171R	0.15
PRAD	chr1	147259879	Missense_Mutation	NA	L179F	0.33
PRAD	chr1	147242731	Frame_Shift_Del	novel	*G11Afs31**	0.4
PRAD	chr1	147293646	Silent	NA	N810N	0.15
READ	chr1	147264424	Splice_Region	NA	F193F	0.34
READ	chr1	147294474	Missense_Mutation	novel	L858I	0.4
SARC	chr1	147264481	Missense_Mutation	novel	E212D	0.08
SARC	chr1	147264476	Nonsense_Mutation	novel	Q211*	0.39
SKCM	chr1	147287689	Missense_Mutation	rs782817356	S759F	0.4
SKCM	chr1	147255838	Missense_Mutation	NA	T125A	0.31	ResIII
SKCM	chr1	147272256	Silent	rs138825728	F415F	0.26
SKCM	chr1	147259853	Missense_Mutation	NA	L171F	0.42
SKCM	chr1	147293638	Missense_Mutation	rs782680914	R808C	0.24
SKCM	chr1	147254918	Missense_Mutation	novel	P97S	0.08	ResIII
SKCM	chr1	147254919	Missense_Mutation	novel	P97L	0.08	ResIII
SKCM	chr1	147254905	Missense_Mutation	NA	L92F	0.42	ResIII
SKCM	chr1	147268811	Missense_Mutation	NA	D340Y	0.28
SKCM	chr1	147256550	Missense_Mutation	NA	S161L	0.22	ResIII
SKCM	chr1	147285379	Missense_Mutation	NA	P637L	0.25
SKCM	chr1	147287692	Missense_Mutation	NA	A760V	0.24
SKCM	chr1	147294423	Missense_Mutation	NA	P841S	0.62
SKCM	chr1	147294424	Missense_Mutation	novel	P841L	0.62
SKCM	chr1	147252689	Missense_Mutation	NA	N65I	0.42	ResIII
STAD	chr1	147254967	Missense_Mutation	novel	E113V	0.1	ResIII
STAD	chr1	147295566	3'UTR	novel		0.46
STAD	chr1	147276121	Missense_Mutation	rs587620686	R468Q	0.11
STAD	chr1	147280184	Missense_Mutation	novel	E566D	0.58
STAD	chr1	147286359	Missense_Mutation	novel	P694S	0.35
STAD	chr1	147294510	Missense_Mutation	NA	T870A	0.11
STAD	chr1	147286300	Missense_Mutation	NA	M674T	0.3
STAD	chr1	147280036	Missense_Mutation	NA	I517T	0.4
STAD	chr1	147284477	Missense_Mutation	rs368838337	R611Q	0.08
STAD	chr1	147259627	Intron	novel		0.75
STAD	chr1	147259627	Intron	novel		0.58
STAD	chr1	147276150	Missense_Mutation	NA	I478L	0.16
STAD	chr1	147285336	Missense_Mutation	novel	G623C	0.04
STAD	chr1	147259627	Intron	novel		0.33
STAD	chr1	147284479	Missense_Mutation	NA	S612P	0.24
UCEC	chr1	147276197	Silent	NA	I493I	0.32
UCEC	chr1	147254894	Missense_Mutation	novel	A89S	0.3	ResIII
UCEC	chr1	147266038	Missense_Mutation	novel	M282I	0.28
UCEC	chr1	147286502	Splice_Site	novel	X741_splice	0.2
UCEC	chr1	147294434	Silent	novel	G844G	0.35
UCEC	chr1	147259817	Intron	novel		0.07
UCEC	chr1	147268797	Missense_Mutation	novel	P335H	0.34
UCEC	chr1	147275453	Missense_Mutation	rs781853748	R457H	0.04
UCEC	chr1	147272220	Missense_Mutation	novel	H403Q	0.27
UCEC	chr1	147275440	Missense_Mutation	novel	A453T	0.43
UCEC	chr1	147268820	Missense_Mutation	NA	T343A	0.47
UCEC	chr1	147259641	Intron	novel		0.21
UCEC	chr1	147294455	Silent	rs202083525	N851N	0.24
UCEC	chr1	147285441	Missense_Mutation	NA	I658V	0.41
UCEC	chr1	147264530	Nonsense_Mutation	novel	E229*	0.36
UCEC	chr1	147259707	Intron	novel		0.43
UCEC	chr1	147280190	Splice_Region	novel	G568G	0.12
UCEC	chr1	147295547	3'UTR	novel		0.25
UCEC	chr1	147259627	Intron	novel		0.31
UCEC	chr1	147293699	Missense_Mutation	rs782570086	F828C	0.39
UCEC	chr1	147252637	Missense_Mutation	NA	S48P	0.03	ResIII
UCEC	chr1	147259627	Intron	novel		1
UCEC	chr1	147286497	Missense_Mutation	rs142193146	V740I	0.12
UCEC	chr1	147259879	Silent	novel	L179L	0.22
UCEC	chr1	147275363	Missense_Mutation	novel	G427D	0.47
UCEC	chr1	147254881	Silent	novel	L84L	0.29
UCEC	chr1	147264481	Silent	novel	E212E	0.32
UCEC	chr1	147295578	3'UTR	novel		0.5
UCEC	chr1	147294480	Missense_Mutation	rs139712616	R860W	0.3
UCEC	chr1	147242828	Missense_Mutation	novel	T42I	0.5	ResIII
UCEC	chr1	147272225	Missense_Mutation	novel	A405V	0.25
UCEC	chr1	147286436	Silent	rs782554675	Y719Y	0.08
UCEC	chr1	147275379	Silent	novel	A432A	0.15
UCEC	chr1	147286327	Missense_Mutation	novel	Q683R	0.11
UCEC	chr1	147275416	Missense_Mutation	rs782423515	P445S	0.11
UCEC	chr1	147275424	Missense_Mutation	rs145656868	N447K	0.24
UCEC	chr1	147256555	Silent	NA	L163L	0.41
UCEC	chr1	147294471	Nonsense_Mutation	rs782007432	R857*	0.58
UCEC	chr1	147252703	Nonsense_Mutation	NA	G70*	0.28	ResIII
UCEC	chr1	147268875	Missense_Mutation	novel	S361Y	0.23
UCEC	chr1	147284424	Silent	novel	E593E	0.2
UCEC	chr1	147291496	Missense_Mutation	novel	G779C	0.36
UCEC	chr1	147252680	Missense_Mutation	rs587758592	H62R	0.25	ResIII
UCEC	chr1	147295698	3'UTR	novel		0.5
UCEC	chr1	147264551	Missense_Mutation	rs587768473	R236C	0.36
UCEC	chr1	147275441	Missense_Mutation	novel	A453V	0.38
UCEC	chr1	147276121	Missense_Mutation	rs587620686	R468Q	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	AMP	0.1222	0.11282
CESC	DEL	0.0339	0.01281
COAD	DEL	0.1242	0.00038973
DLBC	DEL	0.0417	0.0017831
ESCA	AMP	0.3424	0.0022446
HNSC	DEL	0.1169	7.836e-19
KIRC	AMP	0.0682	0.059566
LUAD	DEL	0.0678	2.5961e-13
LUSC	AMP	0.3413	1.6618e-06
PAAD	AMP	0.212	0.085665
PCPG	AMP	0.0988	0.00029562
READ	AMP	0.2061	0.025154
SKCM	AMP	0.4441	9.6912e-06
STAD	DEL	0.0544	0.0040659
TGCT	AMP	0.3333	0.088103

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.011	Kaplan-Meier Survival Analysis
MESO	0.007	Kaplan-Meier Survival Analysis
ACC	0.00066	Kaplan-Meier Survival Analysis
HNSC	0.0031	Kaplan-Meier Survival Analysis
KIRP	0.00065	Kaplan-Meier Survival Analysis
KICH	0.026	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
THCA	0.026	Kaplan-Meier Survival Analysis
LUAD	0.016	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000131778 (Gene tree)
Gene ID: 9557
Gene Symbol: CHD1L
Alias: ALC1
Full Name: chromodomain helicase DNA binding protein 1 like
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 53,126 bases
Position: chr1:147,242,641-147,295,766
Accession: 1916
RBP type: canonical RBP
Summary: This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Overexpression of this gene has been linked to several types of cancers. [provided by RefSeq, Feb 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000358262	ResIII	PF04851.15	6.9e-10	1	1
ENSP00000491225	ResIII	PF04851.15	6.7e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
19038236	Gene expression profiles in HPV-immortalized human cervical cells treated with the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	Chem Biol Interact	2009 Feb 12	Prokopczyk B	doi: 10.1016/j.cbi.2008.10.051

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000492728	CHD1L-209	662	-	-	- (aa)	-	-
ENST00000488864	CHD1L-208	2415	-	ENSP00000482764	56 (aa)	-	A0A087WZM7
ENST00000639534	CHD1L-211	1144	-	ENSP00000491225	219 (aa)	-	A0A1W2PP16
ENST00000369258	CHD1L-202	2967	-	ENSP00000358262	897 (aa)	-	Q86WJ1
ENST00000369259	CHD1L-203	2358	-	ENSP00000358263	693 (aa)	-	Q86WJ1
ENST00000431239	CHD1L-204	2907	-	ENSP00000389031	797 (aa)	-	A0A0A0MSH9
ENST00000485113	CHD1L-207	377	-	-	- (aa)	-	-
ENST00000622533	CHD1L-210	2937	-	ENSP00000480553	82 (aa)	-	A0A087WWW4
ENST00000361293	CHD1L-201	2484	XM_024451049	ENSP00000355100	616 (aa)	XP_024306817	A0A0A0MRH8
ENST00000469625	CHD1L-206	423	-	-	- (aa)	-	-
ENST00000467213	CHD1L-205	2782	-	ENSP00000477985	377 (aa)	-	A0A087WTM4

Gene Model

Click here to download ENSG00000131778's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000131778	Muscle, Skeletal	9.7950000E-005	-
ENSG00000131778	Muscle, Skeletal	4.2620000E-005	-
ENSG00000131778	Muscle, Skeletal	8.5100000E-005	-
ENSG00000131778	Waist-Hip Ratio	1.2330000E-005	-
ENSG00000131778	Hemoglobins	5.0800000E-005	-
ENSG00000131778	Hemoglobins	1.7310000E-006	-
ENSG00000131778	Hemoglobins	3.2920000E-005	-
ENSG00000131778	Hemoglobins	1.8830000E-005	-
ENSG00000131778	Hemoglobins	3.2490000E-006	-
ENSG00000131778	Hemoglobins	1.6950000E-006	-
ENSG00000131778	Hemoglobins	2.7600000E-006	-
ENSG00000131778	Hemoglobins	1.5570000E-005	-
ENSG00000131778	Resistin	6.3080000E-005	-
ENSG00000131778	Resistin	1.6270000E-005	-
ENSG00000131778	Resistin	5.0070000E-005	-
ENSG00000131778	DNA, Mitochondrial	6E-6	25240745

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000131778's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000131778	CHD1L	98	65.296	ENSAPOG00000001539	chd1l	97	64.720	Acanthochromis_polyacanthus
ENSG00000131778	CHD1L	100	90.438	ENSAMEG00000017063	CHD1L	100	90.222	Ailuropoda_melanoleuca
ENSG00000131778	CHD1L	96	66.391	ENSACIG00000001164	chd1l	98	65.076	Amphilophus_citrinellus
ENSG00000131778	CHD1L	97	65.890	ENSAOCG00000014510	chd1l	84	64.906	Amphiprion_ocellaris
ENSG00000131778	CHD1L	99	61.726	ENSAPEG00000017450	chd1l	93	62.884	Amphiprion_percula
ENSG00000131778	CHD1L	98	62.603	ENSAPEG00000017573	chd1l	94	62.238	Amphiprion_percula
ENSG00000131778	CHD1L	100	66.396	ENSATEG00000013058	chd1l	93	65.052	Anabas_testudineus
ENSG00000131778	CHD1L	97	75.541	ENSAPLG00000009976	CHD1L	94	75.592	Anas_platyrhynchos
ENSG00000131778	CHD1L	97	70.370	ENSACAG00000017686	CHD1L	97	69.240	Anolis_carolinensis
ENSG00000131778	CHD1L	100	96.434	ENSANAG00000024347	CHD1L	99	95.768	Aotus_nancymaae
ENSG00000131778	CHD1L	99	64.744	ENSACLG00000019304	chd1l	96	64.212	Astatotilapia_calliptera
ENSG00000131778	CHD1L	99	59.350	ENSAMXG00000012367	chd1l	85	60.424	Astyanax_mexicanus
ENSG00000131778	CHD1L	99	91.091	ENSBTAG00000020831	CHD1L	99	91.091	Bos_taurus
ENSG00000131778	CHD1L	100	96.434	ENSCJAG00000002406	CHD1L	99	95.759	Callithrix_jacchus
ENSG00000131778	CHD1L	100	87.347	ENSCAFG00000010944	CHD1L	100	87.236	Canis_familiaris
ENSG00000131778	CHD1L	100	89.263	ENSCAFG00020020121	CHD1L	99	89.298	Canis_lupus_dingo
ENSG00000131778	CHD1L	99	90.716	ENSCHIG00000013871	CHD1L	99	90.858	Capra_hircus
ENSG00000131778	CHD1L	100	94.165	ENSTSYG00000003005	CHD1L	100	94.021	Carlito_syrichta
ENSG00000131778	CHD1L	100	89.103	ENSCPOG00000009000	CHD1L	99	88.740	Cavia_porcellus
ENSG00000131778	CHD1L	100	90.762	ENSCCAG00000036079	CHD1L	99	91.741	Cebus_capucinus
ENSG00000131778	CHD1L	100	98.055	ENSCATG00000031044	CHD1L	100	97.889	Cercocebus_atys
ENSG00000131778	CHD1L	100	89.194	ENSCLAG00000000880	CHD1L	99	90.022	Chinchilla_lanigera
ENSG00000131778	CHD1L	100	98.217	ENSCSAG00000018386	CHD1L	100	98.000	Chlorocebus_sabaeus
ENSG00000131778	CHD1L	97	77.114	ENSCPBG00000002600	CHD1L	97	76.682	Chrysemys_picta_bellii
ENSG00000131778	CHD1L	100	97.893	ENSCANG00000020239	CHD1L	100	96.111	Colobus_angolensis_palliatus
ENSG00000131778	CHD1L	99	87.055	ENSCGRG00001021624	Chd1l	98	87.141	Cricetulus_griseus_chok1gshd
ENSG00000131778	CHD1L	99	87.055	ENSCGRG00000007554	Chd1l	98	88.313	Cricetulus_griseus_crigri
ENSG00000131778	CHD1L	85	57.500	ENSCSEG00000007030	-	92	57.402	Cynoglossus_semilaevis
ENSG00000131778	CHD1L	99	63.269	ENSCVAG00000002595	chd1l	89	62.734	Cyprinodon_variegatus
ENSG00000131778	CHD1L	97	67.000	ENSDARG00000015471	chd1l	84	66.317	Danio_rerio
ENSG00000131778	CHD1L	100	92.058	ENSDNOG00000019504	CHD1L	100	90.667	Dasypus_novemcinctus
ENSG00000131778	CHD1L	100	84.051	ENSDORG00000013555	Chd1l	99	82.686	Dipodomys_ordii
ENSG00000131778	CHD1L	91	83.452	ENSETEG00000008445	CHD1L	89	85.045	Echinops_telfairi
ENSG00000131778	CHD1L	89	48.503	ENSEBUG00000005791	chd1l	75	76.596	Eptatretus_burgeri
ENSG00000131778	CHD1L	99	91.489	ENSEASG00005007364	CHD1L	99	92.611	Equus_asinus_asinus
ENSG00000131778	CHD1L	99	91.489	ENSECAG00000008915	CHD1L	99	92.611	Equus_caballus
ENSG00000131778	CHD1L	97	53.934	ENSELUG00000016844	chd1l	83	54.850	Esox_lucius
ENSG00000131778	CHD1L	99	90.653	ENSFCAG00000007777	CHD1L	99	90.653	Felis_catus
ENSG00000131778	CHD1L	99	73.779	ENSFALG00000006087	CHD1L	97	72.810	Ficedula_albicollis
ENSG00000131778	CHD1L	97	91.528	ENSFDAG00000012431	CHD1L	98	91.459	Fukomys_damarensis
ENSG00000131778	CHD1L	99	63.607	ENSFHEG00000012420	chd1l	85	64.385	Fundulus_heteroclitus
ENSG00000131778	CHD1L	85	63.863	ENSGMOG00000005076	CHD1L	100	65.896	Gadus_morhua
ENSG00000131778	CHD1L	99	73.333	ENSGALG00000015038	CHD1L	97	72.696	Gallus_gallus
ENSG00000131778	CHD1L	98	65.422	ENSGAFG00000018198	chd1l	97	62.485	Gambusia_affinis
ENSG00000131778	CHD1L	85	63.240	ENSGACG00000014042	chd1l	100	66.221	Gasterosteus_aculeatus
ENSG00000131778	CHD1L	97	76.733	ENSGAGG00000014432	CHD1L	97	76.995	Gopherus_agassizii
ENSG00000131778	CHD1L	100	98.865	ENSGGOG00000001067	CHD1L	100	98.218	Gorilla_gorilla
ENSG00000131778	CHD1L	99	64.401	ENSHBUG00000007464	chd1l	96	64.452	Haplochromis_burtoni
ENSG00000131778	CHD1L	100	88.065	ENSHGLG00000008933	CHD1L	99	88.130	Heterocephalus_glaber_female
ENSG00000131778	CHD1L	100	85.623	ENSHGLG00100007155	CHD1L	100	86.845	Heterocephalus_glaber_male
ENSG00000131778	CHD1L	96	63.866	ENSHCOG00000012787	chd1l	92	62.919	Hippocampus_comes
ENSG00000131778	CHD1L	100	61.551	ENSIPUG00000022617	chd1l	84	60.395	Ictalurus_punctatus
ENSG00000131778	CHD1L	100	87.781	ENSSTOG00000007032	CHD1L	99	81.341	Ictidomys_tridecemlineatus
ENSG00000131778	CHD1L	99	64.448	ENSKMAG00000014358	chd1l	86	63.949	Kryptolebias_marmoratus
ENSG00000131778	CHD1L	99	64.239	ENSLBEG00000023845	chd1l	96	63.758	Labrus_bergylta
ENSG00000131778	CHD1L	97	68.078	ENSLACG00000006262	CHD1L	85	67.206	Latimeria_chalumnae
ENSG00000131778	CHD1L	96	72.454	ENSLOCG00000010574	chd1l	85	72.145	Lepisosteus_oculatus
ENSG00000131778	CHD1L	99	90.000	ENSLAFG00000018136	CHD1L	99	90.952	Loxodonta_africana
ENSG00000131778	CHD1L	100	97.893	ENSMFAG00000043562	CHD1L	100	97.821	Macaca_fascicularis
ENSG00000131778	CHD1L	100	97.893	ENSMMUG00000009024	CHD1L	100	97.667	Macaca_mulatta
ENSG00000131778	CHD1L	100	98.055	ENSMNEG00000039905	CHD1L	100	97.778	Macaca_nemestrina
ENSG00000131778	CHD1L	100	98.379	ENSMLEG00000030900	CHD1L	100	98.111	Mandrillus_leucophaeus
ENSG00000131778	CHD1L	97	64.204	ENSMAMG00000012822	chd1l	97	61.944	Mastacembelus_armatus
ENSG00000131778	CHD1L	99	64.725	ENSMZEG00005020830	chd1l	86	64.644	Maylandia_zebra
ENSG00000131778	CHD1L	99	72.268	ENSMGAG00000014304	CHD1L	98	73.191	Meleagris_gallopavo
ENSG00000131778	CHD1L	96	84.573	ENSMAUG00000004712	-	97	86.842	Mesocricetus_auratus
ENSG00000131778	CHD1L	100	93.193	ENSMICG00000002497	CHD1L	100	91.889	Microcebus_murinus
ENSG00000131778	CHD1L	100	87.380	ENSMOCG00000006305	Chd1l	99	86.667	Microtus_ochrogaster
ENSG00000131778	CHD1L	97	64.667	ENSMMOG00000005964	chd1l	89	61.287	Mola_mola
ENSG00000131778	CHD1L	100	83.306	ENSMODG00000018717	CHD1L	98	82.171	Monodelphis_domestica
ENSG00000131778	CHD1L	99	64.078	ENSMALG00000014675	chd1l	84	63.902	Monopterus_albus
ENSG00000131778	CHD1L	100	87.581	MGP_CAROLIEiJ_G0025401	Chd1l	99	86.242	Mus_caroli
ENSG00000131778	CHD1L	100	86.284	ENSMUSG00000028089	Chd1l	99	86.176	Mus_musculus
ENSG00000131778	CHD1L	100	87.864	MGP_PahariEiJ_G0026845	Chd1l	98	88.175	Mus_pahari
ENSG00000131778	CHD1L	100	88.207	MGP_SPRETEiJ_G0026347	Chd1l	99	87.177	Mus_spretus
ENSG00000131778	CHD1L	100	89.141	ENSMPUG00000000615	CHD1L	99	89.605	Mustela_putorius_furo
ENSG00000131778	CHD1L	100	90.193	ENSMLUG00000007573	CHD1L	99	88.203	Myotis_lucifugus
ENSG00000131778	CHD1L	100	83.866	ENSNGAG00000000908	Chd1l	99	84.686	Nannospalax_galili
ENSG00000131778	CHD1L	96	62.583	ENSNBRG00000006021	chd1l	93	62.544	Neolamprologus_brichardi
ENSG00000131778	CHD1L	100	97.778	ENSNLEG00000000179	CHD1L	100	97.778	Nomascus_leucogenys
ENSG00000131778	CHD1L	98	77.377	ENSOPRG00000006973	CHD1L	99	78.225	Ochotona_princeps
ENSG00000131778	CHD1L	100	83.917	ENSODEG00000002494	CHD1L	99	85.556	Octodon_degus
ENSG00000131778	CHD1L	99	64.563	ENSONIG00000003183	chd1l	87	64.761	Oreochromis_niloticus
ENSG00000131778	CHD1L	91	72.977	ENSOANG00000003068	CHD1L	93	74.093	Ornithorhynchus_anatinus
ENSG00000131778	CHD1L	99	85.950	ENSOCUG00000009336	CHD1L	99	85.950	Oryctolagus_cuniculus
ENSG00000131778	CHD1L	99	62.581	ENSORLG00000003673	chd1l	94	62.702	Oryzias_latipes
ENSG00000131778	CHD1L	98	63.339	ENSORLG00020005123	chd1l	95	64.012	Oryzias_latipes_hni
ENSG00000131778	CHD1L	100	62.379	ENSORLG00015001680	chd1l	96	62.911	Oryzias_latipes_hsok
ENSG00000131778	CHD1L	88	59.680	ENSOMEG00000006109	chd1l	81	61.553	Oryzias_melastigma
ENSG00000131778	CHD1L	100	91.100	ENSOGAG00000008775	CHD1L	100	90.122	Otolemur_garnettii
ENSG00000131778	CHD1L	99	90.835	ENSOARG00000020547	CHD1L	98	92.162	Ovis_aries
ENSG00000131778	CHD1L	100	99.026	ENSPPAG00000039193	CHD1L	100	99.273	Pan_paniscus
ENSG00000131778	CHD1L	99	90.541	ENSPPRG00000010258	CHD1L	99	90.541	Panthera_pardus
ENSG00000131778	CHD1L	100	99.220	ENSPTRG00000001220	CHD1L	100	99.220	Pan_troglodytes
ENSG00000131778	CHD1L	100	98.217	ENSPANG00000009170	CHD1L	100	97.556	Papio_anubis
ENSG00000131778	CHD1L	98	65.455	ENSPKIG00000022166	chd1l	94	64.153	Paramormyrops_kingsleyae
ENSG00000131778	CHD1L	97	76.872	ENSPSIG00000012595	CHD1L	95	77.140	Pelodiscus_sinensis
ENSG00000131778	CHD1L	89	61.194	ENSPMGG00000015884	-	94	60.704	Periophthalmus_magnuspinnatus
ENSG00000131778	CHD1L	98	86.062	ENSPEMG00000013528	Chd1l	99	84.922	Peromyscus_maniculatus_bairdii
ENSG00000131778	CHD1L	100	82.658	ENSPCIG00000030409	CHD1L	100	82.446	Phascolarctos_cinereus
ENSG00000131778	CHD1L	99	64.943	ENSPFOG00000015948	chd1l	84	65.023	Poecilia_formosa
ENSG00000131778	CHD1L	99	64.782	ENSPLAG00000015145	chd1l	96	63.741	Poecilia_latipinna
ENSG00000131778	CHD1L	99	64.848	ENSPMEG00000008720	chd1l	89	64.678	Poecilia_mexicana
ENSG00000131778	CHD1L	97	65.074	ENSPREG00000017885	chd1l	96	63.054	Poecilia_reticulata
ENSG00000131778	CHD1L	99	98.701	ENSPPYG00000000946	CHD1L	99	98.109	Pongo_abelii
ENSG00000131778	CHD1L	96	84.298	ENSPCAG00000005959	CHD1L	99	78.129	Procavia_capensis
ENSG00000131778	CHD1L	99	79.407	ENSPVAG00000006084	CHD1L	99	81.310	Pteropus_vampyrus
ENSG00000131778	CHD1L	100	64.229	ENSPNYG00000013001	chd1l	95	64.569	Pundamilia_nyererei
ENSG00000131778	CHD1L	97	66.223	ENSPNAG00000011881	chd1l	83	65.304	Pygocentrus_nattereri
ENSG00000131778	CHD1L	100	87.580	ENSRNOG00000017669	Chd1l	99	86.696	Rattus_norvegicus
ENSG00000131778	CHD1L	100	98.217	ENSRBIG00000041272	CHD1L	100	96.333	Rhinopithecus_bieti
ENSG00000131778	CHD1L	96	97.815	ENSRROG00000041354	CHD1L	99	95.900	Rhinopithecus_roxellana
ENSG00000131778	CHD1L	100	77.508	ENSSHAG00000017395	CHD1L	97	77.778	Sarcophilus_harrisii
ENSG00000131778	CHD1L	97	67.828	ENSSFOG00015003649	chd1l	96	65.684	Scleropages_formosus
ENSG00000131778	CHD1L	99	61.111	ENSSMAG00000019377	chd1l	98	59.865	Scophthalmus_maximus
ENSG00000131778	CHD1L	98	64.909	ENSSDUG00000019831	chd1l	94	64.167	Seriola_dumerili
ENSG00000131778	CHD1L	98	64.927	ENSSLDG00000012714	chd1l	95	63.732	Seriola_lalandi_dorsalis
ENSG00000131778	CHD1L	100	73.183	ENSSPUG00000016865	CHD1L	98	73.708	Sphenodon_punctatus
ENSG00000131778	CHD1L	97	65.116	ENSSPAG00000017653	chd1l	90	64.830	Stegastes_partitus
ENSG00000131778	CHD1L	100	87.540	ENSSSCG00000006701	CHD1L	98	90.040	Sus_scrofa
ENSG00000131778	CHD1L	97	75.707	ENSTGUG00000013392	-	98	74.941	Taeniopygia_guttata
ENSG00000131778	CHD1L	89	60.417	ENSTRUG00000011753	-	84	60.417	Takifugu_rubripes
ENSG00000131778	CHD1L	94	53.883	ENSTRUG00000020456	-	80	54.680	Takifugu_rubripes
ENSG00000131778	CHD1L	96	60.133	ENSTNIG00000004902	chd1l	99	59.368	Tetraodon_nigroviridis
ENSG00000131778	CHD1L	100	86.710	ENSTTRG00000011711	CHD1L	100	88.421	Tursiops_truncatus
ENSG00000131778	CHD1L	100	89.333	ENSUAMG00000021991	CHD1L	99	90.045	Ursus_americanus
ENSG00000131778	CHD1L	100	89.037	ENSUMAG00000009733	CHD1L	99	89.706	Ursus_maritimus
ENSG00000131778	CHD1L	100	90.113	ENSVVUG00000007316	CHD1L	96	89.444	Vulpes_vulpes
ENSG00000131778	CHD1L	99	63.124	ENSXCOG00000008336	chd1l	85	62.818	Xiphophorus_couchianus
ENSG00000131778	CHD1L	99	65.696	ENSXMAG00000015898	chd1l	96	60.545	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	19661379.	IDA	Function
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	-	TAS	Process
GO:0004003	ATP-dependent DNA helicase activity	19661379.	TAS	Function
GO:0005515	protein binding	19661379.23891004.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	19661379.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0006281	DNA repair	19661379.	TAS	Process
GO:0006293	nucleotide-excision repair, preincision complex stabilization	-	TAS	Process
GO:0006294	nucleotide-excision repair, preincision complex assembly	-	TAS	Process
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	-	TAS	Process
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	-	TAS	Process
GO:0006338	chromatin remodeling	19661379.	IDA	Process
GO:0006974	cellular response to DNA damage stimulus	19661379.	IDA	Process
GO:0016887	ATPase activity	19661379.	IMP	Function
GO:0033683	nucleotide-excision repair, DNA incision	-	TAS	Process
GO:0070911	global genome nucleotide-excision repair	-	TAS	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.