EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29052531	PTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its mRNA stability in breast cancer.	J Exp Clin Cancer Res	2017 Oct 19	Zhou XJ	doi: 10.1186/s13046-017-0620-3.
24884756	RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.	BMC Cancer	2014 May 7	Xue JQ	doi: 10.1186/1471-2407-14-322.
22798430	RBM38 is a direct transcriptional target of E2F1 that limits E2F1-induced proliferation.	Mol Cancer Res	2012 Sep	Feldstein O	-
29288351	RNPC1 inhibits non-small cell lung cancer progression via regulating miR-181a/CASC2 axis.	Biotechnol Lett	2018 Mar	Yang L	doi: 10.1007/s10529-017-2504-1
22214381	Radiation sensitivity of esophageal adenocarcinoma: the contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance.	Radiat Res	2012 Mar	Htte GJ	-
28459215	The expression of RNA-binding protein RBM38 decreased in renal cell carcinoma and represses renal cancer cell proliferation, migration, and invasion.	Tumour Biol	2017 May	Huang W	doi: 10.1177/1010428317701635.
26046131	Integrative genomic analyses of the RNA-binding protein, RNPC1, and its potential role in cancer prediction.	Int J Mol Med	2015 Aug	Ding Z	doi: 10.3892/ijmm.2015.2237
28683467	RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer.	Br J Cancer	2017 Aug 22	Wu J	doi: 10.1038/bjc.2017.204
28399911	The role of c-Myc-RBM38 loop in the growth suppression in breast cancer.	J Exp Clin Cancer Res	2017 Apr 11	Li XX	doi: 10.1186/s13046-017-0521-5.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr20	57407594	Silent	novel	V156V	0.35
BRCA	chr20	57392773	Silent	novel	Q119Q	0.24
BRCA	chr20	57391744	Missense_Mutation	NA	E55Q	0.2	RRM_1
BRCA	chr20	57392701	Silent	novel	P95P	0.25
CESC	chr20	57407815	Missense_Mutation	novel	A230V	0.45
COAD	chr20	57407677	Missense_Mutation	rs754322312	P184Q	0.14
COAD	chr20	57407647	Missense_Mutation	rs766487046	P174L	0.3
COAD	chr20	57392752	Silent	rs753581518	G112G	0.33
COAD	chr20	57407711	Silent	rs542773204	S195S	0.47
COAD	chr20	57407604	Missense_Mutation	rs766651552	A160T	0.11
COAD	chr20	57392741	Missense_Mutation	NA	A109T	0.21
DLBC	chr20	57392745	Missense_Mutation	novel	Y110S	0.27
ESCA	chr20	57408964	3'UTR	novel		0.25
GBM	chr20	57393309	Missense_Mutation	NA	P131R	0.14
HNSC	chr20	57407701	Missense_Mutation	novel	Y192C	0.24
HNSC	chr20	57407710	Missense_Mutation	rs765064896	S195L	0.31
KIRP	chr20	57407946	3'UTR	novel		0.42
LGG	chr20	57407706	Missense_Mutation	rs574040093	A194T	0.59
LUAD	chr20	57407648	Silent	novel	P174P	0.44
LUSC	chr20	57407822	Missense_Mutation	novel	Q232H	0.38
LUSC	chr20	57407738	Silent	novel	G204G	0.31
LUSC	chr20	57392681	Missense_Mutation	NA	E89K	0.21	RRM_1
LUSC	chr20	57407576	Missense_Mutation	rs569633738	I150M	0.18
LUSC	chr20	57392763	Missense_Mutation	rs778455042	R116Q	0.11
LUSC	chr20	57393298	Missense_Mutation	novel	Q127H	0.11
LUSC	chr20	57391815	Silent	NA	G78G	0.57
PAAD	chr20	57391727	Nonsense_Mutation	novel	S49*	0.22	RRM_1
READ	chr20	57407576	Silent	rs569633738	I150I	0.29
READ	chr20	57392717	Missense_Mutation	novel	G101S	0.04
SARC	chr20	57408918	3'UTR	novel		0.4
SKCM	chr20	57407785	Missense_Mutation	NA	P220L	0.43
SKCM	chr20	57407613	Missense_Mutation	NA	P163S	0.54
SKCM	chr20	57407732	Silent	rs780859344	F202F	0.3
SKCM	chr20	57407705	Silent	rs572196610	A193A	0.31
SKCM	chr20	57407628	Missense_Mutation	NA	P168S	0.23
STAD	chr20	57407762	Silent	novel	P212P	0.14
STAD	chr20	57407710	Missense_Mutation	rs765064896	S195L	0.15
STAD	chr20	57407641	Missense_Mutation	NA	Y172C	0.25
STAD	chr20	57407754	Missense_Mutation	rs771577545	A210T	0.13
UCEC	chr20	57409031	3'UTR	novel		0.31
UCEC	chr20	57391633	Missense_Mutation	novel	L18M	0.19
UCEC	chr20	57407627	Silent	rs201839752	S167S	0.36
UCEC	chr20	57392677	Silent	novel	A87A	0.28
UCEC	chr20	57409108	3'UTR	novel		0.29
UCEC	chr20	57392690	Missense_Mutation	novel	C92R	0.38	RRM_1
UCEC	chr20	57407833	Missense_Mutation	novel	D236V	0.41
UCEC	chr20	57408974	3'UTR	rs144029523		0.42
UCEC	chr20	57409165	3'UTR	novel		0.58
UCEC	chr20	57408954	3'UTR	novel		0.21
UCEC	chr20	57392713	Silent	novel	I99I	0.41
UCEC	chr20	57408005	3'UTR	novel		0.5
UCEC	chr20	57409167	3'UTR	novel		0.43
UCEC	chr20	57408038	3'UTR	novel		0.23
UCEC	chr20	57408800	3'UTR	novel		0.31
UCEC	chr20	57407720	Silent	rs751373448	T198T	0.38
UCEC	chr20	57409152	3'UTR	novel		0.31
UCEC	chr20	57408918	3'UTR	novel		0.6
UCEC	chr20	57408917	3'UTR	rs148626444		0.31
UCEC	chr20	57408010	3'UTR	novel		0.38

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
PRAD	AMP	0.0569	0.07085
SARC	AMP	0.323	0.033553
SKCM	AMP	0.455	0.058021

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00013	Kaplan-Meier Survival Analysis
STAD	0.032	Kaplan-Meier Survival Analysis
ACC	0.0015	Kaplan-Meier Survival Analysis
LUSC	0.0049	Kaplan-Meier Survival Analysis
ESCA	0.05	Kaplan-Meier Survival Analysis
PAAD	0.027	Kaplan-Meier Survival Analysis
PCPG	0.035	Kaplan-Meier Survival Analysis
CESC	0.00021	Kaplan-Meier Survival Analysis
LAML	0.0068	Kaplan-Meier Survival Analysis
UCEC	0.015	Kaplan-Meier Survival Analysis
LIHC	0.0033	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
THCA	0.01	Kaplan-Meier Survival Analysis
LUAD	0.0059	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000132819 (Gene tree)
Gene ID: 55544
Gene Symbol: RBM38
Alias: HSRNASEB|SEB4D|seb4B|dJ800J21.2|RNPC1
Full Name: RNA binding motif protein 38
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 17,936 bases
Position: chr20:57,391,398-57,409,333
Accession: 15818
RBP type: canonical RBP
Summary: (RNA Binding Motif Protein 38) is a Protein Coding gene. Diseases associated with RBM38 include Lung Cancer. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RBM24.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000407848	RRM_1	PF00076.22	4.8e-18	1	1
ENSP00000348538	RRM_1	PF00076.22	1.4e-17	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25512531	Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors.	Proc Natl Acad Sci U S A	2014 Dec 30	Zhang J	doi: 10.1073/pnas.1415607112
24663081	Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells.	Int J Mol Sci	2014 Mar 6	Ding C	doi: 10.3390/ijms15034060.
28399911	The role of c-Myc-RBM38 loop in the growth suppression in breast cancer.	J Exp Clin Cancer Res	2017 Apr 11	Li XX	doi: 10.1186/s13046-017-0521-5.
29437973	RNA Binding Protein RBM38 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19, Which Facilitates Viral DNA Replication.	J Virol	2018 Mar 28	Ganaie SS	doi: 10.1128/JVI.02050-17
22371495	The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation.	J Biol Chem	2012 Apr 27	Cho SJ	doi: 10.1074/jbc.M111.326827
26512911	Identification of novel proteins binding the AU-rich element of α-prothymosin mRNA through the selection of open reading frames (RIDome).	RNA Biol	2015	Patrucco L	doi: 10.1080/15476286.2015.1107702.
27346399	[Regulatory effect and mechanism of RNA binding motif protein 38 on the expression of progesterone receptor in human breast cancer ZR-75-1 cells].	Zhonghua Zhong Liu Za Zhi	2016 Jun 23	Lou PP	doi: 10.3760/cma.j.issn.0253-3766.2016.06.005.
26740055	The RNA binding proteins RBM38 and DND1 are repressed in AML and have a novel function in APL differentiation.	Leuk Res	2016 Feb	Wampfler J	doi: 10.1016/j.leukres.2015.12.006
28789338	Role of the long non-coding RNA HOTAIR in hepatocellular carcinoma.	Oncol Lett	2017 Aug	Wu L	doi: 10.3892/ol.2017.6312
29052531	PTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its mRNA stability in breast cancer.	J Exp Clin Cancer Res	2017 Oct 19	Zhou XJ	doi: 10.1186/s13046-017-0620-3.
30843048	Therapeutic modulation of RNA-binding protein Rbm38 facilitates re-endothelialization after arterial injury.	Cardiovasc Res	2019 Mar 7	Sonnenschein K	doi: 10.1093/cvr/cvz063
28459215	The expression of RNA-binding protein RBM38 decreased in renal cell carcinoma and represses renal cancer cell proliferation, migration, and invasion.	Tumour Biol	2017 May	Huang W	doi: 10.1177/1010428317701635.
25823026	PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38.	Oncogene	2015 Nov 26	Zhang M	doi: 10.1038/onc.2015.31
30176896	RBM38 plays a tumor-suppressor role via stabilizing the p53-mdm2 loop function in hepatocellular carcinoma.	J Exp Clin Cancer Res	2018 Sep 3	Ye J	doi: 10.1186/s13046-018-0852-x.
22798430	RBM38 is a direct transcriptional target of E2F1 that limits E2F1-induced proliferation.	Mol Cancer Res	2012 Sep	Feldstein O	-
22710720	MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.	Oncogene	2013 Apr 25	Xu E	doi: 10.1038/onc.2012.238
30567739	Serine 195 phosphorylation in the RNA-binding protein Rbm38 increases p63 expression by modulating Rbm38's interaction with the Ago2-miR203 complex.	J Biol Chem	2019 Feb 15	Zhang Y	doi: 10.1074/jbc.RA118.005779
30591552	Disruption of the Rbm38-eIF4E Complex with a Synthetic Peptide Pep8 Increases p53 Expression.	Cancer Res	2019 Feb 15	Lucchesi CA	doi: 10.1158/0008-5472.CAN-18-2209
20064878	RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability.	Nucleic Acids Res	2010 Apr	Cho SJ	doi: 10.1093/nar/gkp1229
19817877	RNA-binding proteins Rbm38 and Rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways.	Genes Cells	2009 Nov	Miyamoto S	doi: 10.1111/j.1365-2443.2009.01347.x
17050675	RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript.	Genes Dev	2006 Nov 1	Shu L	-
22508983	p73 expression is regulated by RNPC1, a target of the p53 family, via mRNA stability.	Mol Cell Biol	2012 Jul	Yan W	doi: 10.1128/MCB.00215-12
22214381	Radiation sensitivity of esophageal adenocarcinoma: the contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance.	Radiat Res	2012 Mar	Hotte GJ	-
21764855	Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas.	Genes Dev	2011 Jul 15	Zhang J	doi: 10.1101/gad.2069311.
20457941	RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability.	Proc Natl Acad Sci U S A	2010 May 25	Zhang J	doi: 10.1073/pnas.0912594107
25622105	Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation.	Oncotarget	2015 Jan 1	Cho SJ	-
25183497	Backbone-independent nucleic acid binding by splicing factor SUP-12 reveals key aspects of molecular recognition.	Nat Commun	2014 Sep 3	Amrane S	doi: 10.1038/ncomms5595.
27899360	Widespread and dynamic translational control of red blood cell development.	Blood	2017 Feb 2	Alvarez-Dominguez JR	doi: 10.1182/blood-2016-09-741835
24884756	RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.	BMC Cancer	2014 May 7	Xue JQ	doi: 10.1186/1471-2407-14-322.
24375645	RNA-binding protein RBM24 regulates p63 expression via mRNA stability.	Mol Cancer Res	2014 Mar	Xu E	doi: 10.1158/1541-7786.MCR-13-0526
24250749	The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation.	PLoS One	2013 Oct 18	Heinicke LA	doi: 10.1371/journal.pone.0078031
24142875	Glycogen synthase kinase 3 promotes p53 mRNA translation via phosphorylation of RNPC1.	Genes Dev	2013 Oct 15	Zhang M	doi: 10.1101/gad.221739.113.
23912475	Regulation of Mdm2 mRNA stability by RNA-binding protein RNPC1.	Oncotarget	2013 Aug	Zhang J	-
23836903	RNPC1, an RNA-binding protein and a p53 target, regulates macrophage inhibitory cytokine-1 (MIC-1) expression through mRNA stability.	J Biol Chem	2013 Aug 16	Yin T	doi: 10.1074/jbc.M113.480186
27040525	Characterization of the duck (Anas platyrhynchos) Rbm24 and Rbm38 genes and their expression profiles in myoblast and skeletal muscle tissues.	Comp Biochem Physiol B Biochem Mol Biol	2016 Aug	Sun W	doi: 10.1016/j.cbpb.2016.03.008
26988821	[RNPC1 induces sensitivity of HER-2-positive breast cancer BT474 cells to trastuzumab through upregulation of HER2].	Zhonghua Zhong Liu Za Zhi	2016 Mar 23	Li CL	doi: 10.3760/cma.j.issn.0253-3766.2016.03.003.
26046131	Integrative genomic analyses of the RNA-binding protein, RNPC1, and its potential role in cancer prediction.	Int J Mol Med	2015 Aug	Ding Z	doi: 10.3892/ijmm.2015.2237
25881544	Estrogen receptor (ER) was regulated by RNPC1 stabilizing mRNA in ER positive breast cancer.	Oncotarget	2015 May 20	Shi L	-
28645112	-	-	-	-	-
28683467	RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer.	Br J Cancer	2017 Aug 22	Wu J	doi: 10.1038/bjc.2017.204
28850611	The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice.	PLoS One	2017 Aug 29	van den Hoogenhof MMG	doi: 10.1371/journal.pone.0184093
29108232	TAp63γ and deltaNp63γ are regulated by RBM38 via mRNA stability and have an opposing function in growth suppression.	Oncotarget	2017 Jun 13	Yan W	doi: 10.18632/oncotarget.18463
29288351	RNPC1 inhibits non-small cell lung cancer progression via regulating miR-181a/CASC2 axis.	Biotechnol Lett	2018 Mar	Yang L	doi: 10.1007/s10529-017-2504-1
29330147	Genetic Ablation of Rbm38 Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN.	Cancer Res	2018 Mar 15	Zhang J	doi: 10.1158/0008-5472.CAN-17-2457
29520104	The Rbm38-p63 feedback loop is critical for tumor suppression and longevity.	Oncogene	2018 May	Jiang Y	doi: 10.1038/s41388-018-0176-5
29733656	RNA Binding Protein RNPC1 Inhibits Breast Cancer Cell Metastasis via Activating STARD13-Correlated ceRNA Network.	Mol Pharm	2018 Jun 4	Zheng L	doi: 10.1021/acs.molpharmaceut.7b01123
30139030	[Relationship between expression of RBM38 and distant metastasis and prognosis of breast cancer].	Zhonghua Zhong Liu Za Zhi	2018 Aug 23	Zhu L	doi: 10.3760/cma.j.issn.0253-3766.2018.08.007.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000440234	RBM38-205	686	XM_005260446	ENSP00000407848	121 (aa)	XP_005260503	Q9H0Z9
ENST00000344785	RBM38-202	2193	-	ENSP00000345248	123 (aa)	-	F6VZ39
ENST00000371219	RBM38-204	760	-	ENSP00000360263	158 (aa)	-	A6NG75
ENST00000342690	RBM38-201	852	-	ENSP00000343718	77 (aa)	-	E9PSF1
ENST00000356208	RBM38-203	2382	XM_011528885	ENSP00000348538	239 (aa)	XP_011527187	Q9H0Z9

Gene Model

Click here to download ENSG00000132819's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000132819	Myocardial Infarction	1.5641950E-004	-
ENSG00000132819	Forced Expiratory Volume	6.6470000E-005	-
ENSG00000132819	Vital Capacity	8.7770000E-005	-
ENSG00000132819	Erythrocyte Indices	3E-8	28017375
ENSG00000132819	Diabetes Mellitus, Type 2	2E-6	23300278
ENSG00000132819	Erythrocyte Count	2E-19	28017375
ENSG00000132819	Hydroxymethylglutaryl CoA Reductases	4E-6	20339536
ENSG00000132819	Erythrocyte Count	2E-7	28017375
ENSG00000132819	Alcohol Drinking	5E-6	23743675
ENSG00000132819	Erythrocyte Count	4E-13	23222517
ENSG00000132819	Erythrocyte Count	1E-8	20139978
ENSG00000132819	Erythrocyte Indices	1E-8	28017375

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000132819	rs11905479	20	57402703	A	High light scatter reticulocyte count	27863252	[0.031-0.048] unit increase	0.03967122	EFO_0007986
ENSG00000132819	rs35817974	20	57398288	A	Reticulocyte count	27863252	[0.024-0.042] unit increase	0.03262435	EFO_0007986
ENSG00000132819	rs35817974	20	57398288	A	Reticulocyte fraction of red cells	27863252	[0.031-0.049] unit increase	0.04032122	EFO_0007986

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000132819's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000132819	RBM38	82	37.113	ENSG00000122566	HNRNPA2B1	72	37.113
ENSG00000132819	RBM38	62	39.474	ENSG00000147274	RBMX	79	41.935
ENSG00000132819	RBM38	78	30.667	ENSG00000152795	HNRNPDL	54	30.667
ENSG00000132819	RBM38	79	42.373	ENSG00000135097	MSI1	80	36.842
ENSG00000132819	RBM38	94	89.655	ENSG00000112183	RBM24	94	90.667
ENSG00000132819	RBM38	70	34.884	ENSG00000161547	SRSF2	68	33.708
ENSG00000132819	RBM38	72	39.773	ENSG00000244395	RBMY1D	75	43.548
ENSG00000132819	RBM38	64	44.118	ENSG00000135486	HNRNPA1	63	44.118
ENSG00000132819	RBM38	54	40.909	ENSG00000151923	TIAL1	50	40.909
ENSG00000132819	RBM38	59	37.097	ENSG00000107105	ELAVL2	71	37.097
ENSG00000132819	RBM38	72	39.773	ENSG00000234414	RBMY1A1	75	43.548
ENSG00000132819	RBM38	62	30.667	ENSG00000119705	SLIRP	93	30.986
ENSG00000132819	RBM38	69	41.667	ENSG00000099622	CIRBP	93	43.243
ENSG00000132819	RBM38	72	39.773	ENSG00000242389	RBMY1E	75	43.548
ENSG00000132819	RBM38	97	34.667	ENSG00000138668	HNRNPD	73	34.667
ENSG00000132819	RBM38	72	39.773	ENSG00000242875	RBMY1B	75	43.548
ENSG00000132819	RBM38	97	30.864	ENSG00000197451	HNRNPAB	57	34.177
ENSG00000132819	RBM38	81	42.373	ENSG00000153944	MSI2	91	39.286
ENSG00000132819	RBM38	97	35.294	ENSG00000071626	DAZAP1	51	36.250
ENSG00000132819	RBM38	63	32.468	ENSG00000104852	SNRNP70	51	37.500
ENSG00000132819	RBM38	55	37.681	ENSG00000149187	CELF1	88	37.681
ENSG00000132819	RBM38	67	38.667	ENSG00000177733	HNRNPA0	51	38.667

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000132819	RBM38	94	82.051	ENSAPOG00000003301	rbm38	91	59.052	Acanthochromis_polyacanthus
ENSG00000132819	RBM38	94	86.441	ENSAPOG00000009939	-	94	67.117	Acanthochromis_polyacanthus
ENSG00000132819	RBM38	94	81.197	ENSACIG00000000010	rbm38	91	57.082	Amphilophus_citrinellus
ENSG00000132819	RBM38	94	88.889	ENSACIG00000012502	-	100	88.889	Amphilophus_citrinellus
ENSG00000132819	RBM38	94	86.441	ENSAOCG00000012559	RBM38	99	63.525	Amphiprion_ocellaris
ENSG00000132819	RBM38	94	82.051	ENSAOCG00000013497	-	91	59.052	Amphiprion_ocellaris
ENSG00000132819	RBM38	94	82.051	ENSAPEG00000013137	rbm38	99	58.943	Amphiprion_percula
ENSG00000132819	RBM38	94	86.441	ENSAPEG00000023581	-	95	65.126	Amphiprion_percula
ENSG00000132819	RBM38	94	81.197	ENSATEG00000016366	rbm38	94	60.714	Anabas_testudineus
ENSG00000132819	RBM38	94	86.441	ENSATEG00000016710	-	92	66.379	Anabas_testudineus
ENSG00000132819	RBM38	94	89.655	ENSACAG00000016238	RBM38	90	77.727	Anolis_carolinensis
ENSG00000132819	RBM38	100	99.174	ENSANAG00000031959	RBM38	100	99.174	Aotus_nancymaae
ENSG00000132819	RBM38	94	87.288	ENSACLG00000019514	-	92	66.810	Astatotilapia_calliptera
ENSG00000132819	RBM38	94	87.288	ENSAMXG00000015601	-	95	67.391	Astyanax_mexicanus
ENSG00000132819	RBM38	89	82.569	ENSAMXG00000038120	rbm38	76	64.324	Astyanax_mexicanus
ENSG00000132819	RBM38	100	97.521	ENSBTAG00000008105	RBM38	100	96.234	Bos_taurus
ENSG00000132819	RBM38	74	85.393	WBGene00006321	sup-12	59	85.393	Caenorhabditis_elegans
ENSG00000132819	RBM38	100	99.174	ENSCJAG00000019139	RBM38	100	99.174	Callithrix_jacchus
ENSG00000132819	RBM38	100	98.347	ENSCAFG00020021943	RBM38	100	95.816	Canis_lupus_dingo
ENSG00000132819	RBM38	100	96.694	ENSCHIG00000002609	RBM38	100	94.561	Capra_hircus
ENSG00000132819	RBM38	100	99.174	ENSCPOG00000012781	RBM38	100	96.234	Cavia_porcellus
ENSG00000132819	RBM38	100	99.174	ENSCCAG00000036872	RBM38	100	99.174	Cebus_capucinus
ENSG00000132819	RBM38	100	99.174	ENSCATG00000032133	RBM38	100	99.174	Cercocebus_atys
ENSG00000132819	RBM38	100	94.937	ENSCLAG00000005906	RBM38	100	96.087	Chinchilla_lanigera
ENSG00000132819	RBM38	100	99.174	ENSCSAG00000015503	RBM38	100	98.745	Chlorocebus_sabaeus
ENSG00000132819	RBM38	94	92.241	ENSCPBG00000024059	RBM38	100	81.651	Chrysemys_picta_bellii
ENSG00000132819	RBM38	86	79.245	ENSCING00000025102	-	51	73.729	Ciona_intestinalis
ENSG00000132819	RBM38	86	79.245	ENSCSAVG00000001132	-	76	56.098	Ciona_savignyi
ENSG00000132819	RBM38	99	81.667	ENSCANG00000030105	-	89	76.891	Colobus_angolensis_palliatus
ENSG00000132819	RBM38	100	95.041	ENSCGRG00001012928	Rbm38	100	92.469	Cricetulus_griseus_chok1gshd
ENSG00000132819	RBM38	94	86.441	ENSCSEG00000004701	-	93	71.818	Cynoglossus_semilaevis
ENSG00000132819	RBM38	93	77.193	ENSCSEG00000020943	rbm38	60	61.957	Cynoglossus_semilaevis
ENSG00000132819	RBM38	90	83.784	ENSCVAG00000015952	rbm38	91	59.657	Cyprinodon_variegatus
ENSG00000132819	RBM38	91	91.071	ENSCVAG00000005472	-	92	66.809	Cyprinodon_variegatus
ENSG00000132819	RBM38	91	89.286	ENSDARG00000058818	rbm38	92	63.677	Danio_rerio
ENSG00000132819	RBM38	94	94.828	ENSDNOG00000032004	RBM38	100	89.815	Dasypus_novemcinctus
ENSG00000132819	RBM38	88	84.112	ENSEBUG00000015164	rbm38	66	84.112	Eptatretus_burgeri
ENSG00000132819	RBM38	100	97.521	ENSECAG00000007700	RBM38	100	94.979	Equus_caballus
ENSG00000132819	RBM38	100	94.215	ENSEEUG00000013489	RBM38	100	94.167	Erinaceus_europaeus
ENSG00000132819	RBM38	94	82.114	ENSELUG00000005849	-	95	66.245	Esox_lucius
ENSG00000132819	RBM38	94	86.325	ENSELUG00000000585	-	87	65.174	Esox_lucius
ENSG00000132819	RBM38	100	97.521	ENSFCAG00000042916	RBM38	100	97.521	Felis_catus
ENSG00000132819	RBM38	94	91.379	ENSFALG00000010805	RBM38	99	80.208	Ficedula_albicollis
ENSG00000132819	RBM38	91	90.179	ENSFHEG00000006160	-	92	71.759	Fundulus_heteroclitus
ENSG00000132819	RBM38	91	83.036	ENSFHEG00000017748	rbm38	91	57.082	Fundulus_heteroclitus
ENSG00000132819	RBM38	94	86.325	ENSGMOG00000016655	-	96	74.725	Gadus_morhua
ENSG00000132819	RBM38	94	91.379	ENSGALG00000026081	RBM38	100	79.817	Gallus_gallus
ENSG00000132819	RBM38	94	81.197	ENSGACG00000015224	rbm38	98	62.736	Gasterosteus_aculeatus
ENSG00000132819	RBM38	94	84.746	ENSGACG00000009873	-	100	67.556	Gasterosteus_aculeatus
ENSG00000132819	RBM38	94	92.241	ENSGAGG00000001187	RBM38	100	82.110	Gopherus_agassizii
ENSG00000132819	RBM38	94	87.288	ENSHBUG00000011778	-	92	70.776	Haplochromis_burtoni
ENSG00000132819	RBM38	94	81.197	ENSHBUG00000012058	rbm38	97	59.091	Haplochromis_burtoni
ENSG00000132819	RBM38	100	97.521	ENSHGLG00000015077	RBM38	100	92.050	Heterocephalus_glaber_female
ENSG00000132819	RBM38	90	77.477	ENSHCOG00000019040	rbm38	70	64.072	Hippocampus_comes
ENSG00000132819	RBM38	91	87.500	ENSHCOG00000005622	-	54	73.438	Hippocampus_comes
ENSG00000132819	RBM38	94	87.288	ENSIPUG00000019349	-	95	65.086	Ictalurus_punctatus
ENSG00000132819	RBM38	96	94.595	ENSJJAG00000016299	-	93	94.595	Jaculus_jaculus
ENSG00000132819	RBM38	83	79.412	ENSKMAG00000012402	rbm38	98	54.661	Kryptolebias_marmoratus
ENSG00000132819	RBM38	94	82.051	ENSLBEG00000018878	rbm38	91	58.369	Labrus_bergylta
ENSG00000132819	RBM38	94	86.441	ENSLBEG00000016163	RBM38	92	70.320	Labrus_bergylta
ENSG00000132819	RBM38	94	88.889	ENSLOCG00000003456	rbm38	95	71.111	Lepisosteus_oculatus
ENSG00000132819	RBM38	100	98.734	ENSMFAG00000043808	RBM38	98	98.723	Macaca_fascicularis
ENSG00000132819	RBM38	100	99.174	ENSMMUG00000031391	RBM38	100	99.174	Macaca_mulatta
ENSG00000132819	RBM38	100	99.174	ENSMNEG00000034683	RBM38	100	99.174	Macaca_nemestrina
ENSG00000132819	RBM38	89	84.404	ENSMLEG00000043261	-	88	84.404	Mandrillus_leucophaeus
ENSG00000132819	RBM38	94	81.197	ENSMAMG00000024135	rbm38	91	59.227	Mastacembelus_armatus
ENSG00000132819	RBM38	94	87.288	ENSMAMG00000020499	RBM38	95	65.823	Mastacembelus_armatus
ENSG00000132819	RBM38	94	81.197	ENSMZEG00005026036	rbm38	91	57.082	Maylandia_zebra
ENSG00000132819	RBM38	94	87.288	ENSMZEG00005000849	-	92	70.776	Maylandia_zebra
ENSG00000132819	RBM38	100	95.041	ENSMAUG00000021211	Rbm38	100	92.887	Mesocricetus_auratus
ENSG00000132819	RBM38	100	96.835	ENSMICG00000038011	RBM38	100	97.685	Microcebus_murinus
ENSG00000132819	RBM38	100	93.388	ENSMOCG00000008715	Rbm38	100	92.469	Microtus_ochrogaster
ENSG00000132819	RBM38	94	86.441	ENSMMOG00000020051	-	99	66.667	Mola_mola
ENSG00000132819	RBM38	100	87.603	ENSMODG00000016458	RBM38	100	79.253	Monodelphis_domestica
ENSG00000132819	RBM38	94	79.310	ENSMALG00000022327	rbm38	93	56.637	Monopterus_albus
ENSG00000132819	RBM38	94	86.441	ENSMALG00000004680	RBM38	70	74.074	Monopterus_albus
ENSG00000132819	RBM38	100	94.215	MGP_CAROLIEiJ_G0024745	Rbm38	100	94.142	Mus_caroli
ENSG00000132819	RBM38	100	95.570	ENSMUSG00000027510	Rbm38	100	94.561	Mus_musculus
ENSG00000132819	RBM38	100	95.041	MGP_PahariEiJ_G0026186	Rbm38	100	93.724	Mus_pahari
ENSG00000132819	RBM38	100	94.215	MGP_SPRETEiJ_G0025665	Rbm38	100	94.142	Mus_spretus
ENSG00000132819	RBM38	94	99.138	ENSMPUG00000006518	RBM38	93	97.861	Mustela_putorius_furo
ENSG00000132819	RBM38	94	96.552	ENSMLUG00000011140	RBM38	100	92.130	Myotis_lucifugus
ENSG00000132819	RBM38	94	93.151	ENSNGAG00000014017	-	64	93.243	Nannospalax_galili
ENSG00000132819	RBM38	94	82.051	ENSNBRG00000022685	rbm38	97	58.921	Neolamprologus_brichardi
ENSG00000132819	RBM38	94	87.288	ENSNBRG00000022545	-	92	66.810	Neolamprologus_brichardi
ENSG00000132819	RBM38	100	80.992	ENSMEUG00000005475	-	100	80.435	Notamacropus_eugenii
ENSG00000132819	RBM38	100	99.174	ENSODEG00000007980	RBM38	100	97.071	Octodon_degus
ENSG00000132819	RBM38	94	87.288	ENSONIG00000020324	-	92	66.667	Oreochromis_niloticus
ENSG00000132819	RBM38	94	81.197	ENSONIG00000017073	rbm38	93	57.328	Oreochromis_niloticus
ENSG00000132819	RBM38	94	90.517	ENSOANG00000009259	RBM38	90	76.271	Ornithorhynchus_anatinus
ENSG00000132819	RBM38	94	79.487	ENSORLG00000012154	rbm38	91	55.128	Oryzias_latipes
ENSG00000132819	RBM38	94	85.593	ENSORLG00000027180	-	92	64.807	Oryzias_latipes
ENSG00000132819	RBM38	94	80.342	ENSORLG00020017871	rbm38	91	55.983	Oryzias_latipes_hni
ENSG00000132819	RBM38	94	85.593	ENSORLG00020020751	-	95	62.500	Oryzias_latipes_hni
ENSG00000132819	RBM38	94	80.342	ENSORLG00015012606	rbm38	97	57.447	Oryzias_latipes_hsok
ENSG00000132819	RBM38	94	85.593	ENSORLG00015017040	-	92	65.665	Oryzias_latipes_hsok
ENSG00000132819	RBM38	94	86.441	ENSOMEG00000023912	-	92	64.069	Oryzias_melastigma
ENSG00000132819	RBM38	94	79.487	ENSOMEG00000006805	rbm38	91	55.556	Oryzias_melastigma
ENSG00000132819	RBM38	100	98.361	ENSOGAG00000029136	RBM38	100	97.917	Otolemur_garnettii
ENSG00000132819	RBM38	64	97.959	ENSPPAG00000040327	-	93	81.579	Pan_paniscus
ENSG00000132819	RBM38	100	97.521	ENSPPRG00000009507	RBM38	100	97.521	Panthera_pardus
ENSG00000132819	RBM38	94	100.000	ENSPTRG00000045845	-	70	97.656	Pan_troglodytes
ENSG00000132819	RBM38	100	100.000	ENSPTRG00000013661	RBM38	100	100.000	Pan_troglodytes
ENSG00000132819	RBM38	100	99.174	ENSPANG00000020919	-	100	99.174	Papio_anubis
ENSG00000132819	RBM38	99	81.529	ENSPANG00000033127	-	100	76.050	Papio_anubis
ENSG00000132819	RBM38	94	88.034	ENSPKIG00000018122	-	100	88.034	Paramormyrops_kingsleyae
ENSG00000132819	RBM38	94	82.787	ENSPKIG00000025417	rbm38	98	63.115	Paramormyrops_kingsleyae
ENSG00000132819	RBM38	94	92.241	ENSPSIG00000011649	RBM38	97	78.017	Pelodiscus_sinensis
ENSG00000132819	RBM38	94	80.342	ENSPMGG00000011343	rbm38	94	57.983	Periophthalmus_magnuspinnatus
ENSG00000132819	RBM38	91	83.333	ENSPMGG00000017094	-	92	64.378	Periophthalmus_magnuspinnatus
ENSG00000132819	RBM38	100	87.603	ENSPCIG00000013648	RBM38	100	79.253	Phascolarctos_cinereus
ENSG00000132819	RBM38	91	83.929	ENSPFOG00000011658	rbm38	91	58.120	Poecilia_formosa
ENSG00000132819	RBM38	91	91.071	ENSPLAG00000002500	-	92	66.525	Poecilia_latipinna
ENSG00000132819	RBM38	91	83.929	ENSPLAG00000005218	rbm38	91	58.120	Poecilia_latipinna
ENSG00000132819	RBM38	91	83.929	ENSPMEG00000015770	rbm38	91	58.120	Poecilia_mexicana
ENSG00000132819	RBM38	91	84.821	ENSPREG00000007398	rbm38	91	58.547	Poecilia_reticulata
ENSG00000132819	RBM38	100	98.361	ENSPCOG00000026201	RBM38	100	98.361	Propithecus_coquereli
ENSG00000132819	RBM38	95	94.521	ENSPVAG00000006457	RBM38	100	67.364	Pteropus_vampyrus
ENSG00000132819	RBM38	94	80.342	ENSPNYG00000021373	rbm38	97	58.750	Pundamilia_nyererei
ENSG00000132819	RBM38	94	89.744	ENSPNYG00000019727	-	100	89.744	Pundamilia_nyererei
ENSG00000132819	RBM38	94	87.288	ENSPNAG00000015123	-	87	89.286	Pygocentrus_nattereri
ENSG00000132819	RBM38	93	88.596	ENSPNAG00000010596	rbm38	88	64.319	Pygocentrus_nattereri
ENSG00000132819	RBM38	100	95.041	ENSRNOG00000006420	Rbm38	100	94.142	Rattus_norvegicus
ENSG00000132819	RBM38	100	89.256	ENSRROG00000036388	-	100	81.590	Rhinopithecus_roxellana
ENSG00000132819	RBM38	100	96.835	ENSSBOG00000031053	RBM38	100	99.065	Saimiri_boliviensis_boliviensis
ENSG00000132819	RBM38	91	89.286	ENSSFOG00015004453	rbm38	92	69.545	Scleropages_formosus
ENSG00000132819	RBM38	94	82.051	ENSSDUG00000022611	rbm38	91	60.086	Seriola_dumerili
ENSG00000132819	RBM38	94	86.441	ENSSDUG00000021082	RBM38	92	66.524	Seriola_dumerili
ENSG00000132819	RBM38	94	82.051	ENSSLDG00000010845	rbm38	90	63.426	Seriola_lalandi_dorsalis
ENSG00000132819	RBM38	94	86.441	ENSSLDG00000011778	RBM38	92	66.524	Seriola_lalandi_dorsalis
ENSG00000132819	RBM38	94	82.051	ENSSPAG00000011113	rbm38	91	58.798	Stegastes_partitus
ENSG00000132819	RBM38	94	85.593	ENSSPAG00000020989	RBM38	91	69.767	Stegastes_partitus
ENSG00000132819	RBM38	100	98.347	ENSSSCG00000007504	RBM38	100	97.071	Sus_scrofa
ENSG00000132819	RBM38	94	86.441	ENSTRUG00000019869	-	92	68.240	Takifugu_rubripes
ENSG00000132819	RBM38	94	81.197	ENSTRUG00000024954	rbm38	91	55.895	Takifugu_rubripes
ENSG00000132819	RBM38	94	87.288	ENSTNIG00000007093	-	97	70.721	Tetraodon_nigroviridis
ENSG00000132819	RBM38	98	89.076	ENSTBEG00000001689	-	64	89.076	Tupaia_belangeri
ENSG00000132819	RBM38	100	98.347	ENSUAMG00000019780	RBM38	100	97.071	Ursus_americanus
ENSG00000132819	RBM38	100	98.347	ENSVVUG00000017246	RBM38	100	95.816	Vulpes_vulpes
ENSG00000132819	RBM38	94	88.793	ENSXETG00000011268	rbm38	100	74.667	Xenopus_tropicalis
ENSG00000132819	RBM38	94	85.124	ENSXCOG00000017324	-	55	85.124	Xiphophorus_couchianus
ENSG00000132819	RBM38	91	83.929	ENSXMAG00000023662	rbm38	91	58.369	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0006397	mRNA processing	21873635.	IBA	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0010830	regulation of myotube differentiation	-	IEA	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0043484	regulation of RNA splicing	19285943.	IDA	Process
GO:0070935	3'-UTR-mediated mRNA stabilization	21873635.	IBA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

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Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.